Laser detection and treatment all-in-one machine and laser output control method

Abstract

The embodiment of the invention discloses a laser detection and treatment all-in-one machine and a laser output control method. According to one specific embodiment, the laser detection and treatment all-in-one machine comprises Raman detection information acquisition equipment, semiconductor laser output treatment equipment and touch screen processing equipment, the Raman detection information acquisition equipment comprises Raman exciting light output equipment, an exciting light transmission optical fiber, a collimating mirror, a Raman pump light narrow-band pass filter, a replaceable focusing mirror, a reflecting mirror, a Raman signal light transmission optical fiber, a first replaceable double-color piece, a second replaceable double-color piece, a third replaceable double-color piece and a first charge-coupled device camera; the system comprises a first charge-coupled device camera, a second charge-coupled device camera, a third charge-coupled device camera, an upper computer connecting line and an analog-to-digital converter. The Raman detection information acquisition equipment is used for acquiring Raman spectrum data of the to-be-detected object; the touch screen processing device is configured to perform tissue anomaly detection and laser output steps. According to the embodiment, the laser treatment effect is improved, and the operation treatment time is shortened.

Description

Technical Field

[0001] The embodiments of the present disclosure relate to the field of laser technology, and in particular to a laser detection and treatment all-in-one machine and a laser output control method. Background Art

[0002] With the aging of society and changes in lifestyle, the incidence of human tissue lesions or cancers (such as skin tumors and oral cancer) is gradually increasing worldwide. Laser output devices are used to treat various types of tissue lesions and cancers (such as skin tumors and oral cancer), which has driven the growth of market demand. At present, the existing laser output devices used for laser treatment are usually traditional laser output devices.

[0003] However, the above-mentioned traditional laser output devices often have the following technical problems:

[0004] The function of traditional laser output devices is to destroy or remove diseased and cancerous human tissues, and they do not have the function of detecting abnormalities in human tissues (e.g., disease detection, cancer detection). When using traditional laser output devices to remove abnormal tissues, laser output devices without detection functions are limited to the emission of lasers and cannot perform real-time or immediate detection of target tissues, which increases damage to normal tissues and results in poor laser treatment effects. In order to accurately and completely remove abnormal tissues, it is necessary to perform multiple abnormality detections on abnormal tissues. When performing abnormality detection on tissues with the help of other detection equipment (e.g., X-ray tomography (CT) equipment), it takes more time to prepare equipment and position patients. The detection operation steps are numerous, which increases the time of surgical treatment.

[0005] The above information disclosed in this Background section is only for enhancement of understanding of the background of the inventive concept and therefore it may contain information that does not form the prior art that is already known to a person of ordinary skill in the art. Summary of the invention

[0006] The content of this disclosure is used to introduce concepts in a brief form, which will be described in detail in the detailed implementation section below. The content of this disclosure is not intended to identify the key features or essential features of the technical solution claimed for protection, nor is it intended to limit the scope of the technical solution claimed for protection.

[0007] Some embodiments of the present disclosure propose a laser detection and treatment all-in-one machine and a laser output control method to solve one or more of the technical problems mentioned in the above background technology section.

[0008] In a first aspect, some embodiments of the present disclosure provide a laser detection and treatment integrated machine, including: a Raman detection information acquisition device, a semiconductor laser output treatment device, and a touch screen processing device; the above-mentioned Raman detection information acquisition device includes a Raman excitation light output device, an excitation light transmission optical fiber, a collimating mirror, a Raman pump light narrow bandpass filter, a replaceable focusing mirror, a reflecting mirror, a Raman signal light transmission optical fiber, a first replaceable two-color filter, a second replaceable two-color filter, a third replaceable two-color filter, a first charge-coupled device camera, a second charge-coupled device camera, a third charge-coupled device camera, a host computer connection, and an analog-to-digital converter; the above-mentioned Raman excitation light output device is connected to the above-mentioned excitation light transmission optical fiber via a coaxial radio frequency connector; the above-mentioned A Raman detection information acquisition device is used to acquire Raman spectrum data of an object to be detected, and transmit the acquired Raman spectrum data to the above-mentioned touch screen processing device, wherein the above-mentioned Raman spectrum data includes various Raman spectrum sub-data, and the above-mentioned various Raman spectrum sub-data include first Raman spectrum data, second Raman spectrum data and third Raman spectrum data; the above-mentioned touch screen processing device is configured to perform the following tissue abnormality detection and laser output steps: receiving the Raman spectrum data transmitted by the above-mentioned Raman detection information acquisition device; based on the above-mentioned Raman spectrum data, performing tissue abnormality detection on the above-mentioned object to be detected, so as to control the above-mentioned semiconductor laser output treatment device to output a laser corresponding to the Raman spectrum data to the area where the above-mentioned object to be detected is located.

[0009] Optionally, the Raman pump light narrow bandpass filter is replaced via a pluggable slot.

[0010] Optionally, the replaceable focusing lens is replaced by a pluggable replacement method or a threaded replacement method.

[0011] Optionally, the excitation light output by the Raman excitation light output device reaches the collimator through the excitation light transmission optical fiber, and then the excitation light is collimated by the collimator, and then the collimated excitation light reaches the object to be measured through a replaceable focusing mirror, wherein the replaceable focusing mirror focuses the collimated excitation light to the area where the object to be measured is located; the object to be measured emits Raman scattered light under the action of the excitation light; the replaceable focusing mirror focuses the Raman scattered light to the Raman pump light narrow bandpass filter, and enters the Raman signal light transmission optical fiber after being reflected by the Raman pump light narrow bandpass filter and the reflector, and then reaches the first replaceable dichroic filter through the Raman signal light transmission optical fiber, and the first replaceable dichroic filter separates the Raman scattered light in the first preset wavelength range from the Raman scattered light and reflects it to the first charge coupled device camera. , obtaining a first analog electrical signal corresponding to the Raman scattered light in the above-mentioned first preset wavelength range; the Raman scattered light in the first preset wavelength range is separated from the Raman scattered light by the above-mentioned first replaceable dichroic filter, and the Raman scattered light in the second preset wavelength range contained in the Raman scattered light is separated and reflected to the above-mentioned second charge-coupled device camera through the above-mentioned second replaceable dichroic filter to obtain a second analog electrical signal corresponding to the Raman scattered light in the above-mentioned second preset wavelength range; the Raman scattered light in the first preset wavelength range and the Raman scattered light in the second preset wavelength range are separated from the Raman scattered light by the first replaceable dichroic filter and the above-mentioned second replaceable dichroic filter, and the Raman scattered light in the third preset wavelength range is reflected to the above-mentioned third charge-coupled device camera through the above-mentioned third replaceable dichroic filter to obtain a third analog electrical signal corresponding to the Raman scattered light in the above-mentioned third preset wavelength range.

[0012] Optionally, the first analog electrical signal, the second analog electrical signal and the third analog electrical signal are transmitted to the analog-to-digital converter via the host computer connection; the analog-to-digital converter is used to convert the first analog electrical signal into first Raman spectrum data; the analog-to-digital converter is used to convert the second analog electrical signal into second Raman spectrum data; the analog-to-digital converter is used to convert the third analog electrical signal into third Raman spectrum data.

[0013] Optionally, the touch screen processing device is further configured to perform tissue abnormality detection on the above-mentioned object to be tested based on the above-mentioned Raman spectrum data through the following steps, so as to control the above-mentioned semiconductor laser output treatment device to output laser corresponding to the Raman spectrum data to the area where the above-mentioned object to be tested is located, including: obtaining incident wavelength information of the excitation light corresponding to the above-mentioned Raman spectrum data; performing the following Raman detection processing on each Raman spectrum sub-data in each Raman spectrum sub-data included in the above-mentioned Raman spectrum data: generating a Raman spectrum data point information set corresponding to the above-mentioned Raman spectrum sub-data based on the above-mentioned incident wavelength information and the above-mentioned Raman spectrum sub-data; generating a Raman spectrum graph corresponding to the above-mentioned Raman spectrum sub-data based on the above-mentioned Raman spectrum data point information set; performing spectrum graph analysis processing on the above-mentioned Raman spectrum graph to obtain Raman tissue detection information corresponding to the object to be tested; and converting the obtained Raman spectrum sub-data into Raman tissue detection information. The Raman tissue detection information is displayed on a preset detection page; in response to detecting that at least one of the above-mentioned Raman tissue detection information represents a detection abnormality, a laser output control, a start time input box and an end time input box are displayed on the above-mentioned detection page; in response to detecting an input operation acting on the above-mentioned start time input box, the input information corresponding to the above-mentioned output start time input box is determined as the start time information; in response to detecting an input operation acting on the above-mentioned end time input box, the input corresponding to the above-mentioned end time input box is determined as the end time information; in response to detecting a selection operation acting on the above-mentioned laser output control, the above-mentioned semiconductor laser output treatment device is controlled to output a laser corresponding to the above-mentioned at least one Raman tissue detection information representing the abnormality to the area where the above-mentioned object to be tested is located during the time period corresponding to the above-mentioned start time information and the above-mentioned end time information.

[0014] In the second aspect, some embodiments of the present disclosure provide a laser output control method applied to a touch screen processing device included in the above-mentioned laser detection and treatment integrated machine, including: receiving Raman spectrum data transmitted by the above-mentioned Raman detection information acquisition device; based on the above-mentioned Raman spectrum data, performing tissue abnormality detection on the above-mentioned object to be tested, so as to control the above-mentioned semiconductor laser output treatment device to output a laser corresponding to the Raman spectrum data to the area where the above-mentioned object to be tested is located.

[0015] The above-mentioned various embodiments of the present disclosure have the following beneficial effects: through the laser detection and treatment all-in-one machine of some embodiments of the present disclosure, the laser treatment effect is improved and the surgical treatment time is reduced. Specifically, the reason for the poor laser treatment effect and the long surgical treatment time is that the function of the traditional laser output device is to destroy or remove the diseased and cancerous human tissue, and does not have the function of abnormal detection of human tissue (for example, lesion detection, cancer detection). When using the traditional laser output device to remove abnormal tissue, the laser output device without the detection function is limited to the emission of laser, and cannot perform real-time or immediate detection of the target tissue, which increases the damage to normal tissue and the laser treatment effect is poor. In order to accurately and completely remove the abnormal tissue, it is necessary to perform multiple abnormal detections on the abnormal tissue. When performing abnormal detection of tissue with the help of other detection equipment (for example, X-ray tomography (CT) equipment), more time is needed to prepare the equipment and position the patient. The detection operation steps are numerous, which increases the surgical treatment time. Based on this, some embodiments of the laser detection and treatment integrated machine disclosed in the present invention include: Raman detection information acquisition equipment, semiconductor laser output treatment equipment, and touch screen processing equipment; the above-mentioned Raman detection information acquisition equipment includes Raman excitation light output equipment, excitation light transmission optical fiber, collimating mirror, Raman pump light narrow bandpass filter, replaceable focusing mirror, reflecting mirror, Raman signal light transmission optical fiber, first replaceable two-color film, second replaceable two-color film, third replaceable two-color film, first charge coupled device camera, second charge coupled device camera, third charge coupled device camera, host computer connection, analog-to-digital converter; the above-mentioned Raman excitation light output equipment is connected to the above-mentioned excitation light transmission optical fiber through a coaxial radio frequency connector; thus, the Raman spectrum data of the object to be tested can be collected in real time through the Raman detection information acquisition equipment. The Raman detection information acquisition device is used to collect Raman spectrum data of the object to be tested, and transmit the collected Raman spectrum data to the touch screen processing device, wherein the Raman spectrum data includes various Raman spectrum sub-data, and the various Raman spectrum sub-data include first Raman spectrum data, second Raman spectrum data and third Raman spectrum data; the touch screen processing device is configured to perform the following tissue abnormality detection and laser output steps: receiving the Raman spectrum data transmitted by the Raman detection information acquisition device; based on the Raman spectrum data, performing tissue abnormality detection on the object to be tested, so as to control the semiconductor laser output treatment device to output laser corresponding to the Raman spectrum data to the area where the object to be tested is located. Thus, the Raman spectrum data can be analyzed in real time by the touch screen processing device included in the laser detection and treatment all-in-one machine, so as to control the semiconductor laser output treatment device to output laser. The laser detection and treatment all-in-one machine can collect the Raman spectrum data of the object to be tested (such as human tissue) in real time through the Raman detection information acquisition device to perform tissue abnormality detection.It is also possible to perform tissue abnormality detection through a touch screen processing device based on the real-time collection of Raman detection information, so as to control the above-mentioned semiconductor laser output treatment device to output laser corresponding to the Raman spectrum data, thereby reducing damage to normal tissue and improving the laser treatment effect. At the same time, it does not require more time to prepare equipment and position patients, simplifies the detection operation steps, and shortens the surgical treatment time. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] The above and other features, advantages and aspects of the embodiments of the present disclosure will become more apparent with reference to the following detailed description in conjunction with the accompanying drawings. Throughout the accompanying drawings, the same or similar reference numerals represent the same or similar elements. It should be understood that the drawings are schematic and that components and elements are not necessarily drawn to scale.

[0017] Figure 1 is a schematic diagram of the structure of some embodiments of the Raman detection information acquisition device according to the present disclosure;

[0018] Figure 2 is a schematic structural diagram of some embodiments of the semiconductor laser output treatment device according to the present disclosure;

[0019] Figure 3 is a flow chart of some embodiments of the laser output control method suitable for implementing the present disclosure;

[0020] Figure 4 It is a schematic diagram of the structure of some embodiments of the integrated laser detection and treatment machine according to the present disclosure;

[0021] Figure 5 This is a physical picture of the internal test product of the laser detection and treatment all-in-one machine disclosed in the present invention. DETAILED DESCRIPTION

[0022] Embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Although certain embodiments of the present disclosure are shown in the accompanying drawings, it should be understood that the present disclosure can be implemented in various forms and should not be construed as being limited to the embodiments set forth herein. On the contrary, these embodiments are provided to provide a more thorough and complete understanding of the present disclosure. It should be understood that the drawings and embodiments of the present disclosure are only for exemplary purposes and are not intended to limit the scope of protection of the present disclosure.

[0023] It should also be noted that, for ease of description, only the parts related to the invention are shown in the drawings. In the absence of conflict, the embodiments and features in the embodiments of the present disclosure can be combined with each other.

[0024] It should be noted that the concepts such as "first" and "second" mentioned in the present disclosure are only used to distinguish different devices, modules or units, and are not used to limit the order or interdependence of the functions performed by these devices, modules or units.

[0025] It should be noted that the modifications of "one" and "plurality" mentioned in the present disclosure are illustrative rather than restrictive, and those skilled in the art should understand that unless otherwise clearly indicated in the context, it should be understood as "one or more".

[0026] The names of the messages or information exchanged between multiple devices in the embodiments of the present disclosure are only used for illustrative purposes and are not used to limit the scope of these messages or information.

[0027] The present disclosure will be described in detail below with reference to the accompanying drawings and in conjunction with embodiments.

[0028] First, see Figure 1 and Figure 4 , Figure 4 The schematic diagrams of the structures of some embodiments of the integrated laser detection and treatment machine disclosed in the present invention are shown. The integrated laser detection and treatment machine comprises a Raman detection information acquisition device 401 , a semiconductor laser output treatment device 403 , and a touch screen processing device 402 . Figure 1 The schematic diagram of the structure of some embodiments of the Raman detection information acquisition device 401 of the present disclosure is shown. The above-mentioned Raman detection information acquisition device 401 includes: the above-mentioned Raman detection information acquisition device 401 includes a Raman excitation light output device 101, an excitation light transmission optical fiber 102, a collimator 103, a Raman pump light narrow bandpass filter 104, a replaceable focusing mirror 105, a reflector 107, a Raman signal light transmission optical fiber 108, a first replaceable dichroic plate 109, a second replaceable dichroic plate 110, a third replaceable dichroic plate 111, a first charge coupled device camera 1121, a second charge coupled device camera 1122, a third charge coupled device camera 1123, a host computer connection 112, and an analog-to-digital converter. The above-mentioned Raman excitation light output device 101 is connected to the above-mentioned excitation light transmission optical fiber 102 through a coaxial radio frequency connector.

[0029] Among them, the above-mentioned Raman excitation light output device 101 can be a device for outputting Raman excitation light. The above-mentioned Raman excitation light can be light that excites the object to be measured (for example, human tissue) to generate a Raman scattering signal. For example, the above-mentioned Raman excitation light output device 101 can be a Raman laser. The above-mentioned excitation light transmission optical fiber 102 can be an optical fiber (for example, a hand tool optical fiber) for transmitting Raman excitation light. The above-mentioned Raman pump light narrow bandpass filter 104 can be a reflective filter for transmitting Raman excitation light and reflecting Raman scattered light. The above-mentioned replaceable focusing mirror 105 can be a replaceable focusing mirror that focuses the Raman excitation light onto the object to be measured 106. The above-mentioned Raman signal light transmission optical fiber 108 can be an optical fiber for transmitting Raman scattered light. The above-mentioned first replaceable dichroic filter 109 can be a dichroic filter that divides the light that meets the first preset wavelength band in the Raman scattered light into the first charge coupled device camera 1121. The second replaceable dichroic filter 110 may be a dichroic filter that divides the light that meets the second preset wavelength band in the Raman scattered light to the second CCD camera 1122. The third replaceable dichroic filter 111 may be a dichroic filter that divides the light that meets the third preset wavelength band in the Raman scattered light to the third CCD camera 1123. The first CCD camera 1121, the second CCD camera 1122, and the third CCD camera 1123 are all CCD cameras. For example, the first CCD camera 1121 may be an ultraviolet CCD camera. The second CCD camera 1122 may be a visible light CCD camera. The third CCD camera 1123 may be a near infrared CCD camera.

[0030] The Raman detection information acquisition device 401 is used to collect Raman spectrum data of the object to be tested 106, and transmit the collected Raman spectrum data to the touch screen processing device 402. The Raman spectrum data includes various Raman spectrum sub-data, and the various Raman spectrum sub-data include first Raman spectrum data, second Raman spectrum data and third Raman spectrum data. The touch screen processing device 402 is configured to perform the following tissue abnormality detection and laser output steps: receiving the Raman spectrum data transmitted by the Raman detection information acquisition device 401. Based on the Raman spectrum data, the tissue abnormality detection is performed on the object to be tested 106, so as to control the semiconductor laser output treatment device 403 to output the laser corresponding to the Raman spectrum data to the area 228 where the object to be tested 106 is located. The touch screen processing device 402 can control the above-mentioned Raman detection information acquisition device 401 through a timing task to collect Raman spectrum data in real time before or after the above-mentioned semiconductor laser output treatment device 403 outputs laser, so as to control the above-mentioned semiconductor laser output treatment device 403 to output or re-output the laser corresponding to the Raman spectrum data to the area 228 where the above-mentioned object to be measured 106 is located.

[0031] The Raman detection information acquisition device 401 can be connected to the touch screen processing device 402 (such as a computing device of the touch screen) via a USB cable or other high-speed data transmission cable (such as an Ethernet cable). The touch screen processing device 402 can communicate via a serial communication interface (such as RS-232, RS-485, etc.), an Ethernet interface or other high-speed communication interface to control the semiconductor laser output treatment device 403 to output a laser corresponding to the Raman spectrum data to the area 228 where the object to be tested 106 is located.

[0032] Optionally, the Raman pump light narrow bandpass filter 104 is replaced via a pluggable slot.

[0033] Optionally, the replaceable focusing lens 105 is replaced by a pluggable replacement method or a threaded replacement method.

[0034] Optionally, the excitation light output by the Raman excitation light output device 101 reaches the collimator 103 through the excitation light transmission optical fiber 102, and then the excitation light is collimated by the collimator 103, and then the collimated excitation light reaches the object to be measured 106 through the replaceable focusing lens 105. The replaceable focusing lens 105 focuses the collimated excitation light to the area 228 where the object to be measured 106 is located. The object to be measured 106 emits Raman scattered light under the action of the excitation light. The replaceable focusing mirror 105 focuses the Raman scattered light onto the Raman pump light narrow bandpass filter 104, and enters the Raman signal light transmission optical fiber 108 after being reflected by the Raman pump light narrow bandpass filter 104 and the reflector 107, and then reaches the first replaceable dichroic filter 109 through the Raman signal light transmission optical fiber 108. The first replaceable dichroic filter 109 separates the Raman scattered light in the first preset wavelength range from the Raman scattered light and reflects the Raman scattered light to the first charge coupled device camera 1121, thereby obtaining a first analog electrical signal corresponding to the Raman scattered light in the first preset wavelength range. After the Raman scattered light of the first preset wavelength range in the Raman scattered light is separated by the first replaceable dichroic filter 109, the Raman scattered light of the second preset wavelength range contained in the Raman scattered light is separated by the second replaceable dichroic filter 110 and reflected to the second charge coupled device camera 1122, thereby obtaining a second analog electrical signal corresponding to the Raman scattered light of the second preset wavelength range. After the Raman scattered light of the first preset wavelength range and the Raman scattered light of the second preset wavelength range in the Raman scattered light are separated by the first replaceable dichroic filter 109 and the second replaceable dichroic filter 110, the Raman scattered light of the third preset wavelength range is reflected to the third charge coupled device camera 1123 by the third replaceable dichroic filter 111, thereby obtaining a third analog electrical signal corresponding to the Raman scattered light of the third preset wavelength range.

[0035] Optionally, the first analog electrical signal, the second analog electrical signal and the third analog electrical signal are transmitted to the analog-to-digital converter via the host computer connection. The analog-to-digital converter is used to convert the first analog electrical signal into first Raman spectrum data. The analog-to-digital converter is used to convert the second analog electrical signal into second Raman spectrum data. The analog-to-digital converter is used to convert the third analog electrical signal into third Raman spectrum data.

[0036] In the process of adopting technical solutions to solve the problems mentioned in the background technology, the following problems are often accompanied:

[0037] Usually, the laser output by existing semiconductor laser output treatment equipment is mostly a single laser. When treating abnormal tissues (for example, lesions or cancer), due to the differences in the absorption characteristics of lasers by different tissues, the wavelength of a single laser is usually fixed, and the scope of application of laser treatment is small. At the same time, the same tissue may face multiple lesions, and a single laser may not be able to accurately treat diseased tissues with multiple lesions at the same time, resulting in poor laser treatment effects of semiconductor laser output treatment equipment.

[0038] In the face of the above technical problems, the inventor decided to adopt the following solutions:

[0039] Further references Figure 2 , Figure 2Schematic diagrams of the structures of some embodiments of the semiconductor laser output treatment device 403 of the present disclosure are shown. The semiconductor laser output treatment device 403 includes a first laser diode 201, a second laser diode 202, a third laser diode 203, a fourth laser diode 204, a fifth laser diode 205, a sixth laser diode 206, a seventh laser diode 207, a first volume Bragg grating 208, a second volume Bragg grating 209, a third volume Bragg grating 210, a first slow axis collimator 211, a second slow axis collimator 201, a third slow axis collimator 213, a fourth slow axis collimator 214, a fifth slow axis collimator 215, a sixth slow axis collimator 216, a seventh slow axis collimator 217, a reflecting mirror 218, a first dichroic plate 219, a second dichroic plate 220, a third dichroic plate 221, a fourth dichroic plate 222, a fifth dichroic plate 223, a sixth dichroic plate 224, an aspheric focusing mirror 225, a laser output window 226, and a coupler dustproof window 227. Each of the first laser diode 201, the second laser diode 202, the third laser diode 203, the fourth laser diode 204, the fifth laser diode 205, the sixth laser diode 206, and the seventh laser diode 207 can be a laser diode for generating a preset wavelength or a preset wavelength range. Each of the first volume Bragg grating 208, the second volume Bragg grating 209, and the third volume Bragg grating 210 can be used to stabilize the laser output wavelength and narrow the line width. Each of the first volume Bragg grating 208, the second volume Bragg grating 209, the third volume Bragg grating 210, the first slow axis collimator 211, the second slow axis collimator 201, the third slow axis collimator 213, the fourth slow axis collimator 214, the fifth slow axis collimator 215, the sixth slow axis collimator 216, and the seventh slow axis collimator 217 may be a slow axis collimator located at a preset position of a corresponding laser diode among the first laser diode 201, the second laser diode 202, the third laser diode 203, the fourth laser diode 204, the fifth laser diode 205, the sixth laser diode 206, and the seventh laser diode 207. For example, the first laser diode 201 corresponds to the first slow axis collimator 211.

[0040] The first laser diode 201 emits a first preset wavelength laser beam which passes through the first slow axis collimator 211, is reflected by the reflector 218, passes through the first dichroic plate 219, the second dichroic plate 220, the third dichroic plate 221, the fourth dichroic plate 222, the fifth dichroic plate 223, and the sixth dichroic plate 224 to reach the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the first laser beam to the laser output window 226, and then outputs the first laser beam to the laser treatment area 228 through the coupler dustproof window 227, wherein the laser treatment area 228 may be Figure 1The area where the object to be measured 106 is located. The second preset wavelength laser emitted by the second laser diode passes through the second slow axis collimator, is reflected by the first two-color film, passes through the second two-color film, the third two-color film, the fourth two-color film 222, the fifth two-color film, and the sixth two-color film 224 to reach the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the second laser to the laser output window 226, and then outputs it to the laser treatment area 228 through the coupler dustproof window 227. The third preset wavelength laser emitted by the third laser diode passes through the first volume Bragg grating and the third slow axis collimator, is reflected by the second two-color film, passes through the third two-color film, the fourth two-color film 222, the fifth two-color film, and the sixth two-color film to reach the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the third laser to the laser output window 226, and then outputs it to the laser treatment area 228 through the coupler dustproof window 227. The laser light of the fourth preset wavelength emitted by the fourth laser diode passes through the second volume Bragg grating and the fourth slow axis collimator, and is reflected by the third dichroic plate, and passes through the fourth dichroic plate 222, the fifth dichroic plate, and the sixth dichroic plate to reach the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the third laser light to the laser output window 226, and then outputs the laser light to the laser treatment area 228 through the coupler dustproof window 227. The laser light of the fifth preset wavelength emitted by the fifth laser diode passes through the third volume Bragg grating and the fifth slow axis collimator, and is reflected by the fourth dichroic plate 222, and passes through the fifth dichroic plate and the sixth dichroic plate to reach the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the fifth laser light to the laser output window 226, and then outputs the laser light to the laser treatment area 228 through the coupler dustproof window 227. The sixth preset wavelength laser emitted by the sixth laser diode passes through the sixth slow axis collimator, is reflected by the fifth dichroic film, passes through the sixth dichroic film and reaches the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the fifth laser to the laser output window 226, and then outputs it to the laser treatment area 228 through the coupler dustproof window 227. The seventh preset wavelength laser emitted by the seventh laser diode passes through the seventh slow axis collimator, is reflected by the sixth dichroic film and reaches the aspheric focusing mirror 225. The aspheric focusing mirror 225 focuses the seventh laser to the laser output window 226, and then outputs it to the laser treatment area 228 through the coupler dustproof window 227.

[0041] The above-mentioned multi-laser diode configuration structure of the semiconductor laser output treatment device 403 and the related contents of the optical path design between the various optical elements included therein, as an inventive point of the embodiment of the present disclosure, solve the technical problem of "the application scope of the laser treatment of the semiconductor laser output treatment device is small and the laser treatment effect is poor". The factors that lead to the small application scope and poor laser treatment effect of the laser treatment of the semiconductor laser output treatment device are often as follows: the laser output by the existing semiconductor laser output treatment device is usually a single laser. When treating abnormal tissues (for example, lesions or cancer), due to the differences in the absorption characteristics of lasers by different tissues, the wavelength of a single laser is usually fixed, and the application scope of laser treatment is small. At the same time, the same tissue may face multiple lesions, and a single laser may not be able to accurately treat lesion tissues with multiple lesions at the same time, resulting in poor laser treatment effect of the semiconductor laser output treatment device. If the above factors are solved, the application scope of the laser treatment of the semiconductor laser output treatment device can be broadened and the laser treatment effect can be improved. In order to achieve this effect, the present disclosure adopts the multi-laser diode configuration structure of the semiconductor laser output treatment device and the optical path design between the various optical elements included therein. Specifically, the semiconductor laser output treatment device disclosed in the present invention can be built-in with multiple laser diodes in parallel during production. Here, the first laser diode, the second laser diode, the third laser diode, the fourth laser diode, the fifth laser diode, the sixth laser diode, and the seventh laser diode are built-in in the semiconductor laser output treatment device. Thus, multi-band lasers can be generated to solve the problem that different tissues have different absorption characteristics of lasers, and the scope of application of laser treatment is broadened. At the same time, different laser diodes in the above-mentioned laser diodes can be designed to emit lasers of different wavelengths, and by combining multiple laser diodes, on the basis of the optical path design between the various optical elements (for example, Bragg gratings, slow axis collimators, reflectors, dichroic plates, aspheric focusing mirrors) included in the semiconductor laser output treatment device, the simultaneous output of multi-wavelength lasers to the area where the diseased tissues with multiple lesions are located is realized, and the combination of multiple wavelengths of lasers is used to accurately treat the tissues with multiple lesions, thereby improving the laser treatment effect of the semiconductor laser output treatment device.

[0042] Optionally, in some embodiments, the touch screen processing device may be further configured to perform tissue abnormality detection on the object to be tested based on the Raman spectrum data through the following steps, so as to control the semiconductor laser output treatment device to output laser light corresponding to the Raman spectrum data to the area where the object to be tested is located:

[0043] The first step is to obtain the incident wavelength information of the excitation light corresponding to the above Raman spectrum data. In practice, the above touch screen processing device can obtain the incident wavelength information of the excitation light corresponding to the above Raman spectrum data from a preset storage file (such as a preset Word file). The above incident wavelength information can characterize the wavelength of the Raman excitation light. For example, the above incident wavelength information can be "532nm".

[0044] In the second step, the following Raman detection processing is performed on each Raman spectrum sub-data included in the above Raman spectrum data:

[0045] The first sub-step is to generate a set of Raman spectrum data point information corresponding to the Raman spectrum sub-data based on the incident wavelength information and the Raman spectrum sub-data. The Raman spectrum sub-data may include information of various Raman scattered light data points. Each Raman scattered light data point information in the various Raman scattered light data point information includes the wavelength and intensity of the scattered light. For example, the Raman spectrum sub-data may be "(wavelength: 600nm, intensity: 100), (wavelength 700nm, intensity: 120), (wavelength: 800nm, intensity: 150)". In practice, for each Raman scattered light data point information in the various Raman scattered light data point information included in the Raman spectrum sub-data, the touch screen processing device may determine the ratio of the preset value to the wavelength corresponding to the incident wavelength information as the first value. Then the touch screen processing device may determine the ratio of the preset value to the wavelength included in the Raman scattered light data point information as the second value. Afterwards, the touch screen processing device may determine the difference between the first value and the second value as the Raman scattered light offset. Next, the touch screen processing device may determine the Raman scattered light offset and the intensity included in the Raman scattered light data point information as Raman spectrum data point information. Finally, the touch screen processing device may determine the generated individual Raman spectrum data point information as a Raman spectrum data point information set corresponding to the Raman spectrum sub-data.

[0046] The second sub-step is to generate a Raman spectrum graph corresponding to the Raman spectrum sub-data based on the Raman spectrum data point information set. In practice, the touch screen processing device can call a drawing tool (e.g., Matplotlib (Python library)) to generate a curve graph corresponding to the Raman spectrum data point information set as the Raman spectrum graph.

[0047] The third sub-step is to perform spectrum analysis processing on the above Raman spectrum to obtain Raman tissue detection information corresponding to the object to be tested. In practice, the above touch screen processing device can obtain each analytical similarity by comparing the similarity between the above Raman spectrum and each pre-stored spectrum in the pre-constructed spectrum database. Among them, the pre-constructed spectrum database can be a database for storing spectrum and abnormal information corresponding to the spectrum. Each analytical similarity in the above analytical similarities can be represented by cosine similarity. Afterwards, in response to determining that there is at least one analytical similarity greater than a preset value among the above analytical similarities, the above touch screen processing device can determine the analytical similarity with the largest value among the above analytical similarities as the target analytical similarity. Afterwards, the above touch screen processing device can determine the abnormal information corresponding to the target analytical similarity as Raman tissue detection information. The above Raman tissue detection information can be text information, for example, the above Raman tissue detection information can be "detection abnormality, the frequency and intensity of the amide I band and amide III band of the protein are changed compared with normal tissue". In response to determining that none of the above-mentioned resolution similarities has at least one resolution similarity greater than a preset value, the above-mentioned touch screen processing device may determine the text information indicating that the detection is normal as the Raman tissue detection information.

[0048] The third step is to display the obtained Raman tissue detection information on a preset detection page. The preset detection page may be a page for displaying Raman tissue detection information and controlling the semiconductor laser output treatment device to output laser.

[0049] In the fourth step, in response to detecting that at least one of the above Raman tissue detection information represents a detection abnormality, a laser output control, a start time input box, and an end time input box are displayed on the above detection page. The above laser output control may be a page interactive element for controlling the output of laser by a semiconductor laser output treatment device. The above start time input box may be a page interactive element for inputting the start time of laser output. The above end time input box may be a page interactive element for inputting the end time of laser output.

[0050] In a fifth step, in response to detecting an input operation acting on the start time input box, the input information corresponding to the output start time input box is determined as the start time information.

[0051] In step 6, in response to detecting an input operation acting on the end time input box, the input corresponding to the end time input box is determined as the end time information.

[0052] The seventh step, in response to detecting a selection operation acting on the above-mentioned laser output control, controls the above-mentioned semiconductor laser output treatment device to output a laser corresponding to at least one Raman tissue detection information characterizing the abnormality to the area where the above-mentioned object to be tested is located during a time period corresponding to the above-mentioned start time information and the above-mentioned end time information.

[0053] Reference below Figure 3 , Figure 3 The laser output control method applied to the laser detection and treatment integrated machine according to the present disclosure is shown. The laser output control method comprises the following steps:

[0054] Step 301: receiving Raman spectrum data transmitted by a Raman detection information collection device.

[0055] In some embodiments, the execution subject of the laser output control method (eg, a touch screen processing device) may receive Raman spectrum data transmitted by the above-mentioned Raman detection information acquisition device.

[0056] Step 302: Based on the Raman spectrum data, tissue abnormality detection is performed on the object to be tested, so as to control the semiconductor laser output treatment device to output laser light corresponding to the Raman spectrum data to the area where the object to be tested is located.

[0057] In some embodiments, the execution subject may perform tissue abnormality detection on the object to be tested based on the Raman spectrum data to control the semiconductor laser output treatment device to output laser light corresponding to the Raman spectrum data to the area where the object to be tested is located.

[0058] The above-mentioned various embodiments of the present disclosure have the following beneficial effects: through the laser detection and treatment all-in-one machine of some embodiments of the present disclosure, the laser treatment effect is improved and the surgical treatment time is reduced. Specifically, the reason for the poor laser treatment effect and the long surgical treatment time is that the function of the traditional laser output device is to destroy or remove the diseased and cancerous human tissue, and does not have the function of abnormal detection of human tissue (for example, lesion detection, cancer detection). When using the traditional laser output device to remove abnormal tissue, the laser output device without the detection function is limited to the emission of laser, and cannot perform real-time or immediate detection of the target tissue, which increases the damage to normal tissue and the laser treatment effect is poor. In order to accurately and completely remove the abnormal tissue, it is necessary to perform multiple abnormal detections on the abnormal tissue. When performing abnormal detection of tissue with the help of other detection equipment (for example, X-ray tomography (CT) equipment), more time is needed to prepare the equipment and position the patient. The detection operation steps are numerous, which increases the surgical treatment time. Based on this, some embodiments of the laser detection and treatment integrated machine disclosed in the present invention include: Raman detection information acquisition equipment, semiconductor laser output treatment equipment, and touch screen processing equipment; the above-mentioned Raman detection information acquisition equipment includes Raman excitation light output equipment, excitation light transmission optical fiber, collimating mirror, Raman pump light narrow bandpass filter, replaceable focusing mirror, reflecting mirror, Raman signal light transmission optical fiber, first replaceable two-color film, second replaceable two-color film, third replaceable two-color film, first charge coupled device camera, second charge coupled device camera, third charge coupled device camera, host computer connection, analog-to-digital converter; the above-mentioned Raman excitation light output equipment is connected to the above-mentioned excitation light transmission optical fiber through a coaxial radio frequency connector; thus, the Raman spectrum data of the object to be tested can be collected in real time through the Raman detection information acquisition equipment. The Raman detection information acquisition device is used to collect Raman spectrum data of the object to be tested, and transmit the collected Raman spectrum data to the touch screen processing device, wherein the Raman spectrum data includes various Raman spectrum sub-data, and the various Raman spectrum sub-data include first Raman spectrum data, second Raman spectrum data and third Raman spectrum data; the touch screen processing device is configured to perform the following tissue abnormality detection and laser output steps: receiving the Raman spectrum data transmitted by the Raman detection information acquisition device; based on the Raman spectrum data, performing tissue abnormality detection on the object to be tested, so as to control the semiconductor laser output treatment device to output the laser corresponding to the Raman spectrum data to the area where the object to be tested is located. Thus, the Raman spectrum data can be analyzed in real time by the touch screen processing device included in the laser detection and treatment all-in-one machine, so as to control the semiconductor laser output treatment device to output the treatment laser. The laser detection and treatment all-in-one machine can collect the Raman spectrum data of the object to be tested (such as human tissue) in real time through the Raman detection information acquisition device to perform tissue abnormality detection.It is also possible to perform tissue abnormality detection through a touch screen processing device based on the real-time collection of Raman detection information, so as to control the above-mentioned semiconductor laser output treatment device to output laser corresponding to the Raman spectrum data, thereby reducing damage to normal tissue and improving the laser treatment effect. At the same time, it does not require more time to prepare equipment and position patients, simplifies the detection operation steps, and shortens the surgical treatment time.

[0059] The above descriptions are only some preferred embodiments of the present disclosure and an explanation of the technical principles used. Those skilled in the art should understand that the scope of the invention involved in the embodiments of the present disclosure is not limited to the technical solutions formed by a specific combination of technical features, but should also cover other technical solutions formed by any combination of technical features or their equivalent features without departing from the inventive concept. For example, a technical solution formed by replacing the features with (but not limited to) the technical features with similar functions disclosed in the embodiments of the present disclosure.

Claims

1. A laser detection and treatment integrated machine, characterized in that: include: Raman detection information acquisition equipment, semiconductor laser output treatment equipment, touch screen processing equipment; The Raman detection information acquisition device includes a Raman excitation light output device, an excitation light transmission optical fiber, a collimator, a Raman pump light narrow bandpass filter, a replaceable focusing mirror, a reflector, a Raman signal light transmission optical fiber, a first replaceable two-color filter, a second replaceable two-color filter, a third replaceable two-color filter, a first charge-coupled device camera, a second charge-coupled device camera, a third charge-coupled device camera, a host computer connection, and an analog-to-digital converter; The Raman excitation light output device is connected to the excitation light transmission optical fiber via a coaxial radio frequency connector; The Raman detection information acquisition device is used to acquire Raman spectrum data of the object to be detected, and transmit the acquired Raman spectrum data to the touch screen processing device, wherein the Raman spectrum data includes various Raman spectrum sub-data, and the various Raman spectrum sub-data include first Raman spectrum data, second Raman spectrum data and third Raman spectrum data; The touch screen processing device is configured to perform the following tissue abnormality detection and laser output steps: Receiving Raman spectrum data transmitted by the Raman detection information acquisition device; Based on the Raman spectrum data, tissue abnormality detection is performed on the object to be tested, so as to control the semiconductor laser output treatment device to output laser light corresponding to the Raman spectrum data to the area where the object to be tested is located.

2. The integrated laser detection and treatment device according to claim 1, characterized in that: include: The Raman pump light narrow bandpass filter is replaced through a pluggable slot.

3. The integrated laser detection and treatment machine according to claim 1, characterized in that: include: The replaceable focusing lens is replaced by a pluggable replacement method or a threaded replacement method.

4. The integrated laser detection and treatment device according to claim 1, characterized in that: include: The excitation light output by the Raman excitation light output device reaches the collimator through the excitation light transmission optical fiber, and then the excitation light is collimated by the collimator, and then the collimated excitation light reaches the object to be measured through the replaceable focusing mirror, wherein the replaceable focusing mirror focuses the collimated excitation light to the area where the object to be measured is located; The object to be measured emits Raman scattered light under the action of the excitation light; The replaceable focusing mirror focuses the Raman scattered light onto the Raman pump light narrow band pass filter, and the Raman scattered light enters the Raman signal light transmission optical fiber after being reflected by the Raman pump light narrow band pass filter and the reflector, and then reaches the first replaceable dichroic filter through the Raman signal light transmission optical fiber, and the first replaceable dichroic filter separates the Raman scattered light in a first preset wavelength range from the Raman scattered light and reflects the Raman scattered light to the first charge coupled device camera, thereby obtaining a first analog electrical signal corresponding to the Raman scattered light in the first preset wavelength range; The Raman scattered light after the Raman scattered light in the first preset wavelength range is separated by the first replaceable dichroic filter is reflected to the second charge coupled device camera by separating the Raman scattered light in the second preset wavelength range contained in the Raman scattered light through the second replaceable dichroic filter, thereby obtaining a second analog electrical signal corresponding to the Raman scattered light in the second preset wavelength range; The Raman scattered light after the Raman scattered light in the first preset wavelength range and the Raman scattered light in the second preset wavelength range are separated by the first replaceable dichroic filter and the second replaceable dichroic filter is reflected by the third replaceable dichroic filter to the third charge-coupled device camera to obtain a third analog electrical signal corresponding to the Raman scattered light in the third preset wavelength range.

5. The integrated laser detection and treatment machine according to claim 4, characterized in that: include: The first analog electrical signal, the second analog electrical signal and the third analog electrical signal are transmitted to the analog-to-digital converter via the host computer connection; The analog-to-digital converter is used to convert the first analog electrical signal into first Raman spectrum data; The analog-to-digital converter is used to convert the second analog electrical signal into second Raman spectrum data; The analog-to-digital converter is used to convert the third analog electrical signal into third Raman spectrum data.

6. The integrated laser detection and treatment machine according to claim 1, wherein: The touch screen processing device is further configured to perform tissue abnormality detection on the object to be tested based on the Raman spectrum data through the following steps to control the semiconductor laser output treatment device to output laser corresponding to the Raman spectrum data to the area where the object to be tested is located, including: Acquiring incident wavelength information of the excitation light corresponding to the Raman spectrum data; The following Raman detection processing is performed on each Raman spectrum sub-data in each Raman spectrum sub-data included in the Raman spectrum data: Based on the incident wavelength information and the Raman spectrum sub-data, generating a Raman spectrum data point information set corresponding to the Raman spectrum sub-data; generating a Raman spectrum graph corresponding to the Raman spectrum sub-data based on the Raman spectrum data point information set; Performing spectrum analysis processing on the Raman spectrum to obtain Raman tissue detection information corresponding to the object to be tested; Display the obtained Raman tissue detection information on a preset detection page; In response to detecting that at least one of the Raman tissue detection information indicates a detection abnormality, displaying a laser output control, a start time input box, and an end time input box on the detection page; In response to detecting an input operation acting on the start time input box, determining the input information corresponding to the output start time input box as the start time information; In response to detecting an input operation acting on the end time input box, determining the input corresponding to the end time input box as end time information; In response to detecting a selection operation acting on the laser output control, the semiconductor laser output treatment device is controlled to output a laser corresponding to at least one Raman tissue detection information characterizing the abnormality to the area where the object to be tested is located during a time period corresponding to the start time information and the end time information.

7. A laser output control method, applied to the touch screen processing device included in the laser detection and treatment integrated machine according to any one of claims 1 to 6, the method comprising: Receiving Raman spectrum data transmitted by the Raman detection information acquisition device; Based on the Raman spectrum data, tissue abnormality detection is performed on the object to be tested, so as to control the semiconductor laser output treatment device to output laser light corresponding to the Raman spectrum data to the area where the object to be tested is located.

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