A hydrogen peroxide sterilization method

Abstract

The application discloses a hydrogen peroxide sterilization method, comprising the steps of: calculating the actual flow of a delivery pump according to the actual consumption of hydrogen peroxide obtained by weighing in a container per unit time; obtaining the actual slope K1 of a speed-flow curve of the delivery pump according to the ratio of the actual speed of the delivery pump to the actual flow; obtaining a target flow according to the ratio of a set target consumption of hydrogen peroxide to a set target time; obtaining the target consumption currently lacking according to the difference between the set target consumption of hydrogen peroxide and the actual consumption; obtaining a deviation flow according to the ratio of the target consumption currently lacking to the remaining target time; obtaining a corrected flow by summing the target flow and the deviation flow; obtaining a corrected speed of the delivery pump according to the ratio of the corrected flow to the actual slope K1; and obtaining a corrected slope K2 of the speed-flow curve of the delivery pump according to the ratio of the flow obtained according to the corrected speed to the corrected speed. The hydrogen peroxide sterilization method can be repeatedly performed and can improve the accuracy and stability of injection.

Description

Technical Field

[0001] This invention relates to the field of food and pharmaceutical packaging machinery and equipment technology, specifically to a hydrogen peroxide sterilization method. Background Technology

[0002] Existing VHP biological purification solutions for isolators, such as the sterilization system, sterilization method, and isolator described in application number 201910645927.3, include a sterilization system for isolators comprising a supply pipe, a container for holding sterilizing substances, a transfer pump, a weighing component, and an evaporation component located within the isolator cavity. One end of the supply pipe extends into the container, and the other end extends into the evaporation component. The transfer pump is located on the supply pipe and is used to transport the sterilizing substances in the container to the evaporation component at a preset speed to vaporize the sterilizing substances. The weighing component is used to weigh the container in real time to determine whether the sterilizing substances have reached the predetermined consumption amount. A concentration detector is provided within the cavity to detect the concentration of the sterilizing substances. A sterilization method for isolators includes four stages: a dehumidification stage, a lifting stage, a maintenance stage, and a residue removal stage. After biological purification, the process enters the isolator production stage, providing a Class A sterile environment for pharmaceutical production. Dehumidification stage: Compressed air is injected into the cavity to replace and dehumidify the air inside the cavity; Lifting stage: The delivery pump delivers the sterilizing material in the container to the evaporation component for vaporization at a preset speed, while the weighing component weighs the container in real time to determine whether the sterilizing material has reached the predetermined consumption amount; and the concentration detection device detects the concentration of the sterilizing material in the cavity to determine whether the sterilizing material in the cavity is within the preset threshold; Maintenance stage: The speed of the delivery pump is reduced, the air in the cavity is circulated, and the maintenance is maintained for a preset time; Residual removal stage: The rotation of the delivery pump is stopped, and the air in the cavity is replaced and dehumidified.

[0003] Existing sterilization systems for isolators have a slow overall sterilization speed because one end of the supply pipe extends into the container and the other end extends into the evaporation assembly. The delivery pump is located on the supply pipe. During the dehumidification stage, the delivery pump runs stationary, and it only starts to deliver hydrogen peroxide to the supply pipe during the lifting stage.

[0004] The effectiveness of VHP disinfection is influenced by a combination of factors, including hydrogen peroxide solution concentration, vaporization state, hydrogen peroxide solution dosage, target ambient temperature, and the material's operating temperature. The dosage of hydrogen peroxide is a relatively reliable and controllable parameter during the sterilization process. Existing sterilization methods for isolators have the following problems in the entire process:

[0005] The "boost phase" and "maintenance phase" use a constant delivery pump speed and a constant injection time to achieve the same theoretical VHP consumption each time. However, as the delivery pump compresses, the cross-section of the supply pipe (hose) becomes elliptical. The flow rate in the elliptical pipe decreases rapidly at the beginning and gradually slows down later. This causes the flow rate of hydrogen peroxide consumption to change at the same delivery pump speed and time, resulting in poor accuracy and stability of the hydrogen peroxide injection rate within a fixed time.

[0006] The amount of hydrogen peroxide injected during the "boost phase" and "maintenance phase" has a crucial impact on the sterilization effect and is a key factor in achieving the log6 kill effect for microorganisms. Furthermore, because compressed air continuously replaces air during the boost and maintenance phases, injecting hydrogen peroxide at the same rate and for the same duration is crucial for stable VHP (Vacuum-Heat) results. Significant changes in the hydrogen peroxide solution injection rate will greatly affect the vaporization effect. Summary of the Invention

[0007] The technical problem to be solved by the present invention is to overcome the shortcomings of the prior art and provide a hydrogen peroxide sterilization method that is repeatable, low in cost, and can improve the accuracy and stability of hydrogen peroxide injection into sterilization equipment.

[0008] To solve the above-mentioned technical problems, the present invention adopts the following technical solution:

[0009] A hydrogen peroxide sterilization method employs a hydrogen peroxide sterilization system. The system includes a container for holding hydrogen peroxide, a transfer pump, and sterilization equipment. The transfer pump delivers the hydrogen peroxide from the container to the sterilization equipment. The method includes step a: correcting the speed-flow rate curve of the transfer pump.

[0010] The actual flow rate of the delivery pump is calculated based on the actual amount of hydrogen peroxide consumed per unit time by weighing the container.

[0011] The actual slope K1 of the pump speed-flow rate curve is obtained by the ratio of the actual speed of the pump to the actual flow rate.

[0012] The target flow rate is obtained by the ratio of the target hydrogen peroxide consumption to the target time.

[0013] The current missing target consumption amount is obtained by calculating the difference between the set target consumption amount and the actual consumption amount of hydrogen peroxide.

[0014] The deviation flow rate is obtained based on the ratio of the missing target consumption to the remaining target time;

[0015] The corrected flow rate is obtained by summing the target flow rate and the deviation flow rate.

[0016] The corrected speed of the delivery pump is obtained from the ratio of the corrected flow rate to the actual slope K1.

[0017] The corrected slope K2 of the corrected speed-flow curve of the delivery pump is obtained by the ratio of the flow rate obtained from the corrected speed to the corrected speed.

[0018] The delivery pump operates according to the speed-flow curve with a slope of K2.

[0019] As a further improvement to the above technical solution:

[0020] The hydrogen peroxide sterilization system also includes a supply pipeline and a weighing device. The sterilization equipment includes an isolator and an evaporation device located inside the isolator. One end of the supply pipeline is connected to a container, and the other end extends through the outer wall of the isolator to the evaporation device. The delivery pump is located on the supply pipeline, the container is located on the weighing device, the supply pipeline is equipped with a flow detection mechanism, and the end of the supply pipeline extending to the evaporation device is equipped with a blowing mechanism.

[0021] The process includes step S1, the dehumidification stage: the blowing mechanism is turned on, the delivery pump uses the first speed to deliver hydrogen peroxide liquid from the container to the evaporation device, and when the flow detection mechanism detects the flow rate, the delivery pump stops running; step a is performed with the first speed as the actual speed of the delivery pump.

[0022] It also includes step S2, the lifting stage: the delivery pump delivers the hydrogen peroxide in the container to the evaporator for vaporization according to the corrected speed of the dehumidification stage; the previous modified speed is used as the actual speed of the delivery pump and the correction slope K2 of the previous modified speed-flow curve is used as the actual slope K1, and step a is repeated until the weighing device weighs the container to determine that the hydrogen peroxide consumption meets the standard.

[0023] It also includes step S3, maintenance stage: the delivery pump delivers the hydrogen peroxide in the container to the evaporation device for vaporization at the last corrected speed of the lifting stage; the previous modified speed is used as the actual speed of the delivery pump and the correction slope K2 of the previous corrected speed-flow curve is used as the actual slope K1, and step a is repeated until the weighing device weighs the container to determine that the total consumption of hydrogen peroxide meets the standard.

[0024] It also includes step S4, the residue removal stage: the delivery pump reverses to recover the hydrogen peroxide in the supply pipeline into the container, until the weighing device detects no change in weight and stops.

[0025] The flow detection mechanism is located above the isolator and near the point where the supply pipe passes through the isolator, and the container is lower than the evaporator.

[0026] The blowing mechanism includes an air blower, an air pipe, and an air valve. The air blower is aligned with one end of the supply pipe that extends into the evaporation device. One end of the air pipe is connected to the air blower, and the other end is used to connect to the air supply component. The air valve is located on the air pipe.

[0027] The flow detection mechanism includes a clamp-on flow sensor that is clamped onto the supply pipe.

[0028] Compared with the prior art, the advantages of the present invention are as follows:

[0029] The hydrogen peroxide sterilization method of the present invention includes correcting the speed-flow rate curve of the delivery pump. During operation, the speed-flow rate curve of the delivery pump can be corrected after a set target time, so that the delivery pump operates according to a speed-flow rate curve with a slope of K2 (correction slope). Firstly, compared with constant delivery pump speed and other existing methods, the accuracy and stability of hydrogen peroxide injection rate within a fixed time period are improved. Secondly, adjusting the speed of the delivery pump by correcting the speed-flow rate curve does not require increasing equipment costs, resulting in low cost. Thirdly, the speed-flow rate curve of the delivery pump can be corrected at the required stage, and the speed-flow rate curve of the delivery pump can be repeatedly corrected at each stage, further improving the accuracy and stability of hydrogen peroxide injection in the sterilization equipment. Attached Figure Description

[0030] Figure 1 This is a flowchart of the hydrogen peroxide sterilization method of the present invention.

[0031] Figure 2 This is a schematic diagram of the hydrogen peroxide sterilization system of the hydrogen peroxide sterilization method of the present invention.

[0032] Figure 3 This is a speed-flow rate curve of the delivery pump in the hydrogen peroxide sterilization method of the present invention.

[0033] Figure 4 This is a flowchart of another embodiment of the hydrogen peroxide sterilization method of the present invention.

[0034] The labels in the diagram represent:

[0035] 1. Supply pipeline; 2. Container; 3. Transfer pump; 4. Weighing device; 5. Isolator; 6. Evaporation device; 7. Flow detection mechanism; 8. Blowing mechanism; 81. Air blower; 82. Air pipe; 83. Air valve. Detailed Implementation

[0036] The present invention will be further described in detail below with reference to the accompanying drawings and specific embodiments.

[0037] In the description of this invention, it should be understood that the terms "length", "width", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this invention.

[0038] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly specified.

[0039] In this invention, unless otherwise explicitly specified and limited, the terms "assembly," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0040] Example 1:

[0041] Figure 1 This invention illustrates an embodiment of the hydrogen peroxide sterilization method, wherein the hydrogen peroxide sterilization method of this embodiment employs, as follows: Figure 2 The hydrogen peroxide sterilization system shown includes a container 2 for holding hydrogen peroxide, a transfer pump 3, and sterilization equipment. The transfer pump 3 is used to transfer the hydrogen peroxide from the container 2 to the sterilization equipment. The hydrogen peroxide sterilization method includes step a: correcting the speed-flow rate curve of the transfer pump 3.

[0042] The actual flow rate of the delivery pump 3 is calculated based on the actual amount of hydrogen peroxide consumed per unit time by weighing the contents of container 2.

[0043] The actual slope K1 of the speed-flow curve of the delivery pump 3 is obtained by the ratio of the actual speed and the actual flow rate of the delivery pump 3.

[0044] The target flow rate is obtained by the ratio of the target hydrogen peroxide consumption to the target time.

[0045] The current missing target consumption amount is obtained by calculating the difference between the set target consumption amount and the actual consumption amount of hydrogen peroxide.

[0046] The deviation flow rate is obtained based on the ratio of the missing target consumption to the remaining target time;

[0047] The corrected flow rate is obtained by summing the target flow rate and the deviation flow rate.

[0048] The corrected speed of the delivery pump 3 is obtained based on the ratio of the corrected flow rate to the actual slope K1.

[0049] The corrected slope K2 of the corrected speed-flow curve of the delivery pump 3 is obtained by the ratio of the flow rate obtained from the corrected speed to the corrected speed.

[0050] The delivery pump 3 operates according to the speed-flow curve with a slope of K2.

[0051] This hydrogen peroxide sterilization method includes correcting the speed-flow rate curve of the delivery pump 3. During operation, the speed-flow rate curve of the delivery pump 3 can be corrected after a set target time, so that the delivery pump 3 operates according to a speed-flow rate curve with a slope of K2 (correction slope). Firstly, compared with constant speed of delivery pump 3 and other existing methods, the accuracy and stability of hydrogen peroxide injection rate within a fixed time period are improved. Secondly, adjusting the speed of delivery pump 3 by correcting its speed-flow rate curve does not increase equipment costs, resulting in low cost. Thirdly, the speed-flow rate curve of delivery pump 3 can be corrected at the required stage, and the correction can be repeated at each stage, further improving the accuracy and stability of hydrogen peroxide injection in the sterilization equipment.

[0052] Furthermore, in this embodiment, as Figure 2 As shown, the hydrogen peroxide sterilization system also includes a supply pipeline 1 and a weighing device 4. The sterilization equipment includes an isolator 5 and an evaporator 6 located within the isolator 5. One end of the supply pipeline 1 is connected to the container 2, and the other end extends through the outer wall of the isolator 5 to the evaporator 6. A delivery pump 3 is installed on the supply pipeline 1, and the container 2 is installed on the weighing device 4. A flow detection mechanism 7 is installed on the supply pipeline 1, and a blowing mechanism 8 is installed at the end of the supply pipeline 1 extending to the evaporator 6. Specifically, the flow detection mechanism 7 is located at the end of the supply pipeline 1 near the evaporator 6. During the sterilization process where the delivery pump 3 delivers hydrogen peroxide, the blowing mechanism 8 is activated, which facilitates the vaporization of the hydrogen peroxide and improves the sterilization effect.

[0053] Furthermore, in this embodiment, step S1, dehumidification stage, is included: the blowing mechanism 8 is turned on, the delivery pump 3 adopts the first speed to deliver hydrogen peroxide liquid from the container 2 to the evaporation device 6, and when the flow detection mechanism 7 detects the flow, the delivery pump 3 stops running; step a is performed with the first speed as the actual speed of the delivery pump 3.

[0054] During the dehumidification stage, when the flow detection mechanism 7 detects the flow rate, it stops the operation of the delivery pump 3, allowing the supply pipeline 1 to be filled with hydrogen peroxide liquid in advance. This reduces the time required to fill the supply pipeline 1 with hydrogen peroxide liquid in subsequent stages, thereby improving work efficiency.

[0055] Furthermore, this embodiment also includes step S2, the lifting stage: the delivery pump 3 delivers the hydrogen peroxide in container 2 to the evaporator 6 for vaporization at the corrected speed of the dehumidification stage; the previous modified speed is used as the actual speed of the delivery pump 3, and the correction slope K2 of the previous corrected speed-flow curve is used as the actual slope K1. Step a is repeated until the weighing device 4 weighs container 2 to determine that the hydrogen peroxide consumption meets the standard. In the lifting stage, step a is repeated to improve the accuracy and stability of hydrogen peroxide injection into the sterilization equipment during the lifting stage.

[0056] Furthermore, this embodiment also includes step S3, a maintenance phase: the delivery pump 3 delivers the hydrogen peroxide in container 2 to the evaporator 6 for vaporization at the final corrected speed of the lifting phase; the previously modified speed is used as the actual speed of the delivery pump 3, and the modified slope K2 of the previous correction curve is used as the actual slope K1, and step a is repeated until the weighing device 4 weighs container 2 to determine that the total consumption of hydrogen peroxide meets the standard. In the maintenance phase, step a is repeated to improve the accuracy and stability of hydrogen peroxide injection into the sterilization equipment during the maintenance phase.

[0057] Furthermore, this embodiment also includes step S4, the residue removal stage: the transfer pump 3 reverses to recover the hydrogen peroxide in the supply pipeline 1 into the container 2, until the weighing device 4 detects no change in weight and stops. In the residue removal stage, the reverse rotation of the transfer pump 3 recovers the liquid hydrogen peroxide in the supply pipeline 1, reducing the residual liquid in the supply pipeline 1 and avoiding errors in the next sterilization operation.

[0058] Furthermore, in this embodiment, the flow detection mechanism 7 is located above the isolator 5 and near the point where the supply pipe 1 passes through the isolator 5, and the container 2 is lower than the evaporator 6. The location of the flow detection mechanism 7 above the isolator 5 and near the point where the supply pipe 1 passes through the isolator 5 facilitates, during the dehumidification stage, filling the supply pipe 1 with hydrogen peroxide liquid when the flow detection mechanism 7 detects a flow rate. The lower position of the container 2 compared to the evaporator 6 facilitates the complete drainage of the hydrogen peroxide liquid from the supply pipe 1 during the residual discharge stage.

[0059] Furthermore, in this embodiment, the blowing mechanism 8 includes an air blowing head 81, an air pipe 82, and an air valve 83. The air blowing head 81 is aligned with one end of the supply pipe 1 extending into the evaporation device 6. One end of the air pipe 82 is connected to the air blowing head 81, and the other end is used to connect to the air supply assembly. The air valve 83 is located on the air pipe 82. During the process of the delivery pump 3 starting to deliver hydrogen peroxide liquid, the air valve 83 opens, and the air supply assembly supplies air to the air blowing head 81 through the air pipe 82. The air blowing head 81 blows away the hydrogen peroxide liquid flowing out of the liquid outlet of the supply pipe 1.

[0060] Furthermore, in this embodiment, the flow detection mechanism 7 includes a clamp-on flow sensor clipped onto the supply pipe 1. The clamp-on flow sensor can both detect the flow rate of the supply pipe 1 and act as a valve for the supply pipe 1.

[0061] Furthermore, in this embodiment, the delivery pump 3 can be a peristaltic pump, a plunger pump, or the like, whose speed-flow curve is as follows: Figure 3 The pump body shows a linear relationship.

[0062] Example 2:

[0063] Figure 4 Another embodiment of the hydrogen peroxide sterilization method of the present invention is shown. This embodiment uses the hydrogen peroxide sterilization system of Embodiment 1, and includes step a: correcting the speed-flow rate curve of the delivery pump 3.

[0064] The actual flow rate of the delivery pump 3 is calculated based on the actual amount of hydrogen peroxide consumed per unit time by weighing the contents of container 2.

[0065] The actual slope K1 of the speed-flow curve of the delivery pump 3 is obtained by the ratio of the actual speed and the actual flow rate of the delivery pump 3.

[0066] The target flow rate is obtained by the ratio of the target hydrogen peroxide consumption to the target time.

[0067] The current missing target consumption amount is obtained by calculating the difference between the set target consumption amount and the actual consumption amount of hydrogen peroxide.

[0068] The deviation flow rate is obtained based on the ratio of the missing target consumption to the remaining target time;

[0069] The corrected flow rate is obtained by summing the target flow rate and the deviation flow rate.

[0070] The corrected speed of the delivery pump 3 is obtained based on the ratio of the corrected flow rate to the actual slope K1.

[0071] The corrected slope K2 of the corrected speed-flow curve of the delivery pump 3 is obtained by the ratio of the flow rate obtained from the corrected speed to the corrected speed.

[0072] The delivery pump 3 operates according to the speed-flow curve with a slope of K2.

[0073] The speed-flow curve of the transfer pump 3 shows a linear relationship between speed and flow rate that is very close to a straight line. In this case, the actual injection rate value can often correspond to the actual transmission flow rate. By correcting the speed-flow curve, the speed-flow curve can be reused.

[0074] The control of the hydrogen peroxide injection system throughout the VHP phase is as follows:

[0075] "Dehumidification stage":

[0076] In the first step, during the "dehumidification stage", the hydrogen peroxide liquid is transported from the container 2 to the evaporation device 6 by the transfer pump 3 at the first speed. When the flow detection mechanism 7 detects that the liquid in the supply pipeline 1 is stable, the transfer pump 3 is stopped.

[0077] The second step is to calculate the hydrogen peroxide injection time and consumption through the weighing device 4 below container 2 based on the first rotation speed of the dehumidification stage, and correct the rotation speed-flow curve of the delivery pump 3 to improve the accuracy of the hydrogen peroxide injection rate in the "lifting stage".

[0078] "Advancing Phase":

[0079] The third step is to obtain the target consumption and target time set in the "lifting stage" to get the target flow rate, and then obtain the second speed through the speed-flow curve of the delivery pump 3 after correction.

[0080] Fourth step: Every 5 minutes of cumulative operation of the transfer pump 3, calculate the current missing target consumption (deviation consumption); based on the 5-minute consumption and speed, correct the speed-flow curve of the transfer pump 3;

[0081] The fifth step is to obtain the corrected speed (corrected speed) based on the target flow rate and the speed-flow rate curve of the corrected delivery pump 3; then, the current missing target consumption is evenly distributed to the speed that should be replenished in the remaining time, and accumulated to the corrected speed to obtain the third speed. The fourth and fifth steps are repeated.

[0082] Step six: When the "enhancement phase" is over, the "maintenance phase" begins.

[0083] "Maintenance Phase"

[0084] Step 7: Obtain the target consumption and target time for the "maintenance phase" and obtain the fourth speed through the corrected "speed-flow curve of delivery pump 3";

[0085] Step 8: Every 5 minutes of cumulative operation of delivery pump 3, calculate the current missing target consumption.

[0086] Step 9: Based on the consumption and speed over 5 minutes, adjust the speed-flow curve of delivery pump 3;

[0087] Step 10: Based on the target flow rate and the corrected speed-flow rate curve of the delivery pump 3, obtain the corrected speed (corrected speed); then distribute the current missing target consumption evenly to the speed that should be replenished in the remaining time, and add it to the corrected speed to obtain the fifth speed. Steps 8 to 10 are repeated.

[0088] Step 11: When the "maintenance phase" is over, proceed to the "residue removal phase".

[0089] "Residue Removal Stage":

[0090] Step 12: The delivery pump 3 reverses to return the liquid from the supply pipe 1 to the container 2, and stops when the weighing device 4 detects no change in weight.

[0091] Step 13: The injection and distribution system is now complete, and the speed-flow curve of the delivery pump 3 is corrected. When the delivery pump 3 runs again, the speed will be calculated based on the set flow rate and the latest speed-flow curve of the delivery pump 3.

[0092] The speed-flow curve correction and usage method of transfer pump 3 are described below:

[0093] The speed-flow rate curve correction method for delivery pump 3 is as follows:

[0094] 1. Actual flow rate g / Min = Actual consumption g / Actual time Min

[0095] 2. The actual slope K1 of the speed-flow curve of the transfer pump 3 (actual consumption per revolution per minute g / min*rpm) = actual flow rate g / Min / actual speed rpm; (g / min*rpm represents the slope of the linear function of the "speed-flow curve of the transfer pump 3").

[0096] The method for correcting the rotational speed is as follows:

[0097] 1. Target flow rate g / min = Set target consumption g / Set target time min;

[0098] 2. Deviation flow rate g / min = Current missing target consumption g / Remaining target time min;

[0099] 3. Corrected flow rate g / min = Target flow rate g / min + Deviation flow rate g / min;

[0100] 4. Corrected speed rpm = Corrected flow rate g / min / Actual slope K1 of the speed-flow curve of the delivery pump 3.

[0101] While the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the invention. Any person skilled in the art can make many possible variations and modifications to the technical solutions of the present invention, or modify them into equivalent embodiments, without departing from the scope of the present invention. Therefore, any simple modifications, equivalent changes, and modifications made to the above embodiments based on the technical essence of the present invention, without departing from the scope of the present invention, should fall within the protection scope of the present invention.

Claims

1. A hydrogen peroxide sterilization method characterized by, The hydrogen peroxide sterilization system is used for sterilization, which comprises a container (2) for containing hydrogen peroxide, a delivery pump (3) for delivering hydrogen peroxide in the container (2) to a sterilization device, and a weighing device (4), and the hydrogen peroxide sterilization method comprises the following steps: a. correcting the speed-flow curve of the delivery pump (3); The actual flow of the delivery pump (3) is calculated according to the actual consumption of hydrogen peroxide in the container (2) per unit time; The actual slope K1 of the speed-flow curve of the delivery pump (3) is obtained according to the ratio of the actual speed to the actual flow of the delivery pump (3); The target flow is obtained according to the ratio of the set target consumption of hydrogen peroxide to the set target time; The current lack of target consumption is obtained according to the difference between the set target consumption and the actual consumption of hydrogen peroxide; The deviation flow is obtained according to the ratio of the lack of target consumption to the remaining target time; The correction flow is obtained by summing the target flow and the deviation flow; The correction speed of the delivery pump (3) is obtained according to the ratio of the correction flow to the actual slope K1; The correction slope K2 of the speed-flow curve of the delivery pump (3) is obtained according to the ratio of the flow obtained according to the correction speed to the correction speed; The delivery pump (3) operates according to the speed-flow curve with a slope of K2; The actual speed of the delivery pump (3) is the previous modified speed, and the actual slope K1 is the previous correction slope K2 of the speed-flow curve, and the step a is repeated until the weighing device (4) weighs the container (2) and determines that the consumption of hydrogen peroxide meets the standard.

2. The hydrogen peroxide sterilization method according to claim 1, characterized in that: The hydrogen peroxide sterilization system further comprises a supply pipeline (1), the sterilization device comprises an isolator (5) and an evaporation device (6) located in the isolator (5), one end of the supply pipeline (1) is connected with the container (2), the other end of the supply pipeline (1) extends to the evaporation device (6) through the outer wall of the isolator (5), the delivery pump (3) is arranged on the supply pipeline (1), the container (2) is arranged on the weighing device (4), a flow detection mechanism (7) is arranged on the supply pipeline (1), and the one end of the supply pipeline (1) extending to the evaporation device (6) is provided with a blowing mechanism (8).

3. The hydrogen peroxide sterilization method according to claim 2, characterized by, The steps S1 and S2 are further included, wherein the blowing mechanism (8) is opened, the delivery pump (3) adopts a first speed to deliver hydrogen peroxide liquid from the container (2) to the evaporation device (6), and when the flow detection mechanism (7) detects the flow, the operation of the delivery pump (3) is stopped; the first speed is taken as the actual speed of the delivery pump (3), and the step a is performed.

4. The hydrogen peroxide sterilization method according to claim 3, characterized by, The step S2 further includes a lifting stage: the delivery pump (3) delivers hydrogen peroxide in the container (2) to the evaporation device (6) for gasification according to the modified speed in the dehumidification stage.

5. The hydrogen peroxide sterilization method according to claim 4, characterized in that, The method further comprises a step S3, a maintaining stage: the delivery pump (3) delivers the hydrogen peroxide in the container (2) to the evaporation device (6) for gasification at the last modified rotating speed of the lifting stage; the previous modified rotating speed is taken as the actual rotating speed of the delivery pump (3) and the modified slope K2 of the previous modified rotating speed-flow curve is taken as the actual slope K1, and the step a is repeated until the weighing device (4) weighs the container (2) and judges that the total consumption of the hydrogen peroxide reaches the standard.

6. The hydrogen peroxide sterilization method according to claim 5, characterized in that, The method further comprises a step S4, a residual discharging stage: the delivery pump (3) is reversed to recover the hydrogen peroxide in the supply pipeline (1) to the container (2), and stops when the weighing device (4) weighs and detects that the weight is unchanged.

7. The hydrogen peroxide sterilization method of claim 2, wherein: The flow detection mechanism (7) is located above the isolator (5) and close to the position where the supply pipeline (1) passes through the isolator (5), and the container (2) is lower than the evaporation device (6).

8. The hydrogen peroxide sterilization method of claim 2, wherein: The blowing mechanism (8) comprises a gas blowing head (81), a gas pipe (82) and a gas valve (83), the gas blowing head (81) is arranged in alignment with the end of the supply pipeline (1) extending to the evaporation device (6), one end of the gas pipe (82) is connected with the gas blowing head (81) and the other end is used for connecting with a gas supply assembly, and the gas valve (83) is arranged on the gas pipe (82).

9. The hydrogen peroxide sterilization process according to any one of claims 2 to 8, characterized in that: The flow detection mechanism (7) comprises a clamp type flow sensor clamped on the supply pipeline (1).

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