Q-switched thulium laser thrombus ablation device

Abstract

The invention provides a Q-switched thulium laser thrombus ablation device. Comprising a Q-switched thulium laser generation assembly used for generating Q-switched thulium laser; the thrombus ablation catheter comprises a catheter body, an optical fiber and an optical fiber driving assembly. The optical fiber is arranged in the catheter main body and is used for acquiring Q-switched thulium laser and emitting the Q-switched thulium laser towards thrombus in a blood vessel; the optical fiber driving assembly comprises a transmission part and an optical fiber driving unit, the transmission part is arranged between the catheter body and the optical fiber, and the transmission part is in transmission connection with the optical fiber; and one end of the transmission part extends to the outside of the catheter main body and is in transmission connection with the optical fiber driving unit.

Description

Technical Field

[0001] The invention belongs to the field of medical surgical laser equipment, and in particular relates to a Q-switched thulium laser thrombus ablation device. Background Art

[0002] Thrombosis is the main cause and complication of cardiovascular disease, which can lead to myocardial infarction, acute ischemic stroke or venous thromboembolism. When tissues such as fibrin, red blood cells, platelets and white blood cells are deposited and coagulated in blood vessels, thrombi will form, disrupting blood flow. Thrombi in different parts of the human body, at different formation speeds and in different areas have structural differences, but they all cause damage to the body. At present, the incidence of thrombosis is extremely high. Rapid, effective and safe thrombus ablation technology is a favorable means to maintain human health and reduce social burdens.

[0003] Laser thrombolysis is closely related to laser wavelength, pulse width and power. Pulsed laser has the advantages of high intensity, high precision, low damage to surrounding tissues and few postoperative complications. Therefore, it is widely used in clinical medicine. Different biological tissues have the characteristics of absorbing lasers of different specific wavelengths. The mechanism of action of laser thrombolysis is mainly divided into photochemical effect, photothermal effect and photomechanical effect. The action mechanism of laser thrombolysis is to apply laser of a specific wavelength to thrombus, destroy the molecular bonds of biological tissue or directly ablate tissue through thermal action to achieve the purpose of thrombolysis. Laser that can be effectively absorbed by biological tissue will make it easier to achieve accurate, effective and safe thrombolysis.

[0004] The therapeutic effect of existing thrombus ablation devices is not ideal, and how to provide a thrombus ablation device based on laser thrombolysis has become a top priority. Summary of the invention

[0005] The present invention provides a Q-switched thulium laser thrombus ablation device, which can ensure a good thrombus ablation effect while ensuring that the laser causes less damage to the human body. It includes: A Q-switched thulium laser generating component, used for generating a Q-switched thulium laser; A thrombus ablation catheter, comprising a catheter body, an optical fiber, and an optical fiber drive assembly; The optical fiber is arranged in the catheter body, and is used to obtain the Q-switched thulium laser and emit the Q-switched thulium laser toward the thrombus in the blood vessel; The optical fiber drive assembly includes a transmission member and an optical fiber drive unit. The transmission member is arranged between the catheter body and the optical fiber, and the transmission member is transmission-connected to the optical fiber. One end of the transmission member extends to the outside of the catheter body and is transmission-connected to the optical fiber drive unit.

[0006] Optionally, the pulse width of the Q-switched thulium laser is 30-1000ns.

[0007] Optionally, the repetition rate of the Q-switched thulium laser is 200 Hz to 200 kHz.

[0008] Optionally, the average power of the Q-switched thulium laser is 0-30W.

[0009] Optionally, the diameter of the movable optical fiber is 50-600 μm.

[0010] Optionally, the thulium laser generating device adopts a master oscillator power amplification structure, comprising: A seed light generating component and a laser amplifying component connected in sequence via thulium-doped optical fibers; The seed light generating component is used to generate the seed light of the thulium laser, and includes: A first grating and a second grating, an acousto-optic modulation device, a first laser and a first pump light stripping unit sequentially arranged between the first grating and the second grating, and a first laser isolation unit arranged behind the second grating, wherein the first laser isolation unit is used to control unidirectional transmission of seed light; The laser amplification component is used to amplify the seed light to form a thulium laser that meets the requirements, including: a plurality of second lasers coupled to the thulium-doped optical fiber, a second pump light stripping unit and a second laser isolation unit, wherein the second laser isolation unit is used to control the unidirectional transmission of the thulium laser.

[0011] Optionally, the optical fiber driving unit comprises a driving motor, the transmission member is a transmission tube, the inner surface of the transmission tube has a plurality of protrusions, the surface of the protrusions is covered with a coating, and the coating comprises a rubber coating.

[0012] Optionally, the Q-switched thulium laser thrombus ablation device further comprises: An infusion component comprises an infusion unit and an infusion pipeline, wherein the infusion pipeline is the gap between the protrusions.

[0013] Optionally, the Q-switched thulium laser treatment device has a first working mode and a second working mode; In the first working mode, a cavity is provided between the optical fiber and the end of the catheter body close to the thrombus, and the cavity is connected to the infusion pipeline; In the second working mode, the optical fiber is flush with an end of the catheter body that is close to the thrombus.

[0014] Optionally, the Q-switched thulium laser thrombus ablation device further comprises: The expansion component comprises an expansion member driving unit and an expansion member, wherein the expansion member is arranged outside the catheter body, and the expansion member driving unit is used for driving the expansion member to expand or contract.

[0015] The beneficial effects brought by the technical solution provided by the present invention are: The present invention provides a Q-switched thulium laser thrombus ablation device, comprising a Q-switched thulium laser generating component and a thrombus ablation catheter, wherein the thrombus ablation catheter comprises a catheter body, an optical fiber and an optical fiber driving component. The Q-switched thulium laser generating component is used to generate a Q-switched thulium laser, and the thrombus ablation catheter is used to deliver the Q-switched thulium laser to the thrombus in the patient's blood vessel. The optical fiber is arranged in the catheter body, and the optical fiber can be moved to the thrombus by controlling the movement of the thrombus ablation catheter. The optical fiber driving component is used to further accurately control the position of the optical fiber in the catheter body, thereby accurately controlling the distance between the optical fiber and the thrombus. In the present invention, a nanosecond optical fiber thulium laser (Q-switched thulium laser) with a high peak power is formed and output to the in vivo lumen environment for surgical treatment. The high peak power of the Q-switched thulium laser can better achieve thermal ablation and thermal explosion effects, and the narrow pulse width of the Q-switched thulium laser can effectively prolong the thermal relaxation time of the tissue, thereby avoiding the temperature around the treatment point from rising to the extent of damaging normal tissue. By using Q-switched thulium laser for thrombus ablation, the thrombus ablation effect can be ensured and the laser can be prevented from causing damage to the human body. The distance between the optical fiber and the thrombus lesion can be controlled by the optical fiber drive component. The dominant position of the photomechanical effect or photoacoustic effect in the thrombus ablation process can be adjusted by changing the distance to meet the needs of different vascular environments. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the technical solutions in the present invention or the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 A schematic diagram of the structure of a Q-switched thulium laser thrombus ablation device provided by the present invention; Figure 2 A schematic diagram of the structure of a Q-switched thulium laser generating assembly provided by the present invention; Figure 3 A schematic diagram of the structure of a thrombus ablation catheter provided by the present invention; Figure 4 This is a schematic diagram of the structure of another thrombus ablation catheter provided in this embodiment.

[0018] The reference numerals are as follows: 1: Q-switched thulium laser generating assembly; 11: seed light generating assembly; 111: first grating; 112: acousto-optic modulation device; 113: first laser; 114: first beam combiner; 115: first pump light stripping unit; 116: second grating; 117: first laser isolation unit; 12: laser amplifying assembly; 121: second laser; 122: second beam combiner; 123: second pump light stripping unit; 124: second laser isolation unit; 13: thulium-doped fiber; 2: thrombus ablation catheter; 21: catheter body; 22: optical fiber; 23: optical fiber drive assembly; 231: transmission member; 2311: transmission tube; 2312: protrusion; 232: optical fiber drive unit; 3: Infusion assembly; 31: Infusion unit; 32: Infusion line; 4: expansion assembly; 41: expansion drive unit; 42: expansion; 43: delivery pipeline. DETAILED DESCRIPTION

[0019] In order to make the purpose, technical solution and advantages of the present invention clearer, the technical solution of the present invention will be clearly and completely described below in conjunction with the drawings in the present invention. Obviously, the described embodiments are part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0020] Before formally introducing the technical solution of this application, the main inventive concept of this application is briefly introduced: First, about thulium laser.

[0021] Existing thulium lasers are usually used to crush stones in the medical field, while the present application uses thulium lasers for thrombus ablation. The basic principle is as follows: the wavelength of thulium lasers is at the strong absorption peak of water, and can be completely absorbed by water within a very short distance in water, which can better vaporize and cut tissues and has higher cutting accuracy. When the thulium laser is close to water-rich tissues, precise ablation can be achieved without further transmission and diffusion; when the thulium laser is far away from the target tissue in a liquid environment, liquid media such as water absorb the laser energy to form cavitation, generating strong shock waves and high-speed microjets. This photomechanical effect can also effectively remove plaques such as thrombi, and the effect of clearing plaques is more significant. However, since the thulium laser energy is completely absorbed by water at a very short distance, it is easy to cause excessive local temperature rise, resulting in unnecessary thermal damage.

[0022] Second, perform Q-switching on the thulium laser.

[0023] The extremely high instantaneous power of the Q-switched pulsed thulium laser can produce a micro-explosion effect on biological tissues, combining the advantages of the photothermal effect and the photomechanical effect, concentrating the impact force and the heat-affected zone in the target area, greatly reducing the damage to the surrounding tissues caused by the shock wave and heat diffusion. In addition, the beam quality and collimation characteristics of the Q-switched thulium laser are good, and it has a high energy density and low loss, making it an ideal choice for laser medical treatment. In this application, the ultra-short pulse width and ultra-high peak power output of the thulium laser are achieved through the self-developed Q-switched optical path. During the implementation process, the same output energy can be concentrated in a shorter time, so that the thermal relaxation time per unit time will be more sufficient. Combined with pulse shaping technology, the additional thermal effect of the thulium laser is greatly reduced. (That is, first, ultra-short pulse width and ultra-high peak power output are achieved through Q-switching; second, high peak power and short pulse width are beneficial to reduce long-term heat accumulation, making up for the inherent disadvantages of traditional thulium lasers in thrombus ablation.) Based on the above principle, the present application forms a Q-switched thulium laser treatment system for thrombus ablation, which ensures the ablation effect on thrombus while preventing the thulium laser from causing damage to the human body. For the specific technical solution, please refer to the following embodiment.

[0024] Figure 1 This is a schematic diagram of the structure of a Q-switched thulium laser thrombus ablation device provided by the present invention. Figure 1 ,include: A Q-switched thulium laser generating component 1, used for generating a Q-switched thulium laser; Figure 3 This is a schematic diagram of the structure of a thrombus ablation catheter provided by the present invention. Figure 1 and Figure 3 , a thrombus ablation catheter 2, comprising a catheter body 21, an optical fiber 22 and an optical fiber driving assembly 23; The optical fiber 22 is disposed in the catheter body 21 and is used to obtain the Q-switched thulium laser and emit the Q-switched thulium laser toward the thrombus in the blood vessel; The optical fiber driving assembly 23 includes a transmission member 231 and an optical fiber driving unit 232. The transmission member 231 is arranged between the catheter body 21 and the optical fiber 22, and the transmission member 231 is transmission-connected to the optical fiber 22; one end of the transmission member 231 extends to the outside of the catheter body 21 and is transmission-connected to the optical fiber driving unit 232.

[0025] The present invention provides a Q-switched thulium laser thrombus ablation device, comprising a Q-switched thulium laser generating component and a thrombus ablation catheter, wherein the thrombus ablation catheter comprises a catheter body, an optical fiber and an optical fiber driving component. The Q-switched thulium laser generating component is used to generate a Q-switched thulium laser, and the thrombus ablation catheter is used to deliver the Q-switched thulium laser to the thrombus in the patient's blood vessel. The optical fiber is arranged in the catheter body, and the optical fiber can be moved to the thrombus by controlling the movement of the thrombus ablation catheter. The optical fiber driving component is used to further accurately control the position of the optical fiber in the catheter body, thereby accurately controlling the distance between the optical fiber and the thrombus. In the present invention, a nanosecond optical fiber thulium laser (Q-switched thulium laser) with a high peak power is formed and output to the in vivo lumen environment for surgical treatment. The high peak power of the Q-switched thulium laser can better achieve thermal ablation and thermal explosion effects, and the narrow pulse width of the Q-switched thulium laser can effectively prolong the thermal relaxation time of the tissue, thereby avoiding the temperature around the treatment point from rising to the extent of damaging normal tissue. By using Q-switched thulium laser for thrombus ablation, the thrombus ablation effect can be ensured and the laser can be prevented from causing damage to the human body. The distance between the optical fiber and the thrombus lesion can be controlled by the optical fiber drive component. The dominant position of the photomechanical effect or photoacoustic effect in the thrombus ablation process can be adjusted by changing the distance to meet the needs of different vascular environments.

[0026] In this embodiment, the Q-switched thulium laser generating component 1 can use acousto-optic Q-switching or any other Q-switching technology to perform Q-switching operation on the thulium laser.

[0027] Figure 2 This is a schematic diagram of the structure of a Q-switched thulium laser generating assembly provided by the present invention. Figure 2 , including: the thulium laser generating device 1 adopts a main oscillation power amplification structure, including: A seed light generating component 11 and a laser amplifying component 12 connected in sequence via a thulium-doped optical fiber 13; The seed light generating component 11 is used to generate the seed light of the thulium laser, and includes: A first grating 111 and a second grating 116, an acousto-optic modulation device 112, a first laser 113 and a first pump light stripping unit 115 arranged in sequence between the first grating 111 and the second grating 116, and a first laser isolation unit 117 arranged behind the second grating, wherein the first laser isolation unit is used to control the unidirectional transmission of the seed light; The laser amplification component 12 is used to amplify the seed light to form a thulium laser that meets the requirements, including: a plurality of second lasers 121 coupled to the thulium-doped optical fiber, a second pump light stripping unit 123 and a second laser isolation unit 124, wherein the second laser isolation unit 123 is used to control the unidirectional 21 transmission of the thulium laser.

[0028] In this embodiment, the first laser 113 is coupled to the thulium-doped optical fiber 13 through the first beam combiner 114 , and the second laser 121 is coupled to the thulium-doped optical fiber 13 through the second beam combiner 122 .

[0029] In this embodiment, the first laser 113 and the second laser 121 are pump sources, including semiconductor lasers.

[0030] In this embodiment, a pulse signal generator may be used to provide an input signal to the acousto-optic modulation device 112 .

[0031] In this embodiment, the thulium-doped optical fiber 13 is a double-clad thulium-doped optical fiber.

[0032] In this embodiment, the first pump light stripping unit 115 and the second pump light stripping unit 123 include cladding light strippers.

[0033] In this embodiment, the first laser isolation unit 117 and the second laser isolation unit 124 are isolators.

[0034] In this embodiment, the seed source of the acousto-optic Q-switching mainly consists of a first grating (i.e., a high-reflection grating), an acousto-optic modulation device, a first laser (i.e., a semiconductor laser), a first beam combiner, a double-clad thulium-doped optical fiber, a cladding light stripper, and a second grating (i.e., a low-reflection grating). An acousto-optic modulator with pigtail output at both ends is inserted into the cavity as an active Q-switching device. A pulse signal generator provides a driving signal for the acousto-optic modulator, which can conveniently adjust the parameters such as the frequency and duty cycle of the laser. The pump source is a 30 W semiconductor laser (103). The pump light is coupled into a double-clad thulium-doped optical fiber with a core diameter of 10 μm and a cladding diameter of 130 μm through a (1+1)*1 beam combiner. A pair of high- and low-reflection gratings with a central wavelength of 1940 nm form a resonant cavity to oscillate and select the laser's emission wavelength. The cladding light stripper is used to strip the remaining pump light. After being emitted from the low-reflection device, the laser passes through the first laser isolation unit (also known as the isolator) to prevent the return light from causing adverse effects on the optical path and ensure the unidirectional propagation of the light beam.

[0035] The amplifier stage (i.e., the laser amplification component) uses two 35 W 793 nm semiconductor lasers, which are coupled into a double-clad thulium-doped fiber with a core diameter of 25 μm and a cladding diameter of 250 μm through a (2+1)*1 beam combiner to gain-amplify the seed light. The remaining pump light is then stripped off through the second laser stripping unit (i.e., the cladding light stripper). Finally, the timing-adjustable nanosecond pulse thulium laser is output through the second laser isolation unit (i.e., the isolator). The central wavelength of the output light is 1940 nm.

[0036] In this embodiment, the pulse width of the Q-switched thulium laser is in the nanosecond range of 30 to 1000 ns.

[0037] Exemplarily, the pulse width of the Q-switched thulium laser may be 500ns.

[0038] In this embodiment, a Q-switched thulium laser with a pulse width of nanoseconds is used. The duration of a single laser pulse is one order of magnitude less than the laser-induced bubble annihilation time (the latter is in microseconds), which can ensure that the laser will not penetrate the liquid layer and damage human tissue when operating at a certain distance.

[0039] In this embodiment, the peak power of the Q-switched thulium laser is 0-20 kW, and the average power of the Q-switched thulium laser is 0-30 W.

[0040] Exemplarily, the peak power of the Q-switched thulium laser is 50 kW, and the average power of the Q-switched thulium laser is 20 W.

[0041] In this embodiment, the increase in peak power is beneficial to the explosive ablation of hard thrombus. The average power is within 30 watts, which meets the tissue ablation requirements and avoids the temperature rise caused by high average power, which causes additional thermal damage.

[0042] In this embodiment, the repetition rate of the Q-switched thulium laser is 200 Hz to 200 kHz.

[0043] Exemplarily, the repetition rate of the Q-switched thulium laser is 100 kHz.

[0044] In this embodiment, the repetition rate is adjustable over a wide range. A low repetition rate is beneficial to the ablation of soft thrombi, while a high repetition rate is beneficial to the ablation of hard thrombi. At the same time, it has a larger pulse width shaping space and can achieve complex time domain distribution of pulse width, such as pulse trains, Moses pulses, etc.

[0045] In this embodiment, the peak power, pulse width and repetition rate distribution that can be tunable over a wide range are combined to achieve complex spatiotemporal distribution of pulse width, such as pulse trains, Moses pulses, etc. Both are combinations of multiple pulses. Ordinary pulse lasers are one pulse after another, while each pulse of a pulse train and a Moses pulse is composed of multiple small pulses. The peak power of each small pulse does not need to be the same, and the number of small pulses can be set as needed, which has a large editing space. This mode has a wide range of uses and can flexibly allocate energy. For example, when ablating biological tissue, micro-drilling, cutting, and surface treatment can be performed. Distributing energy through multiple pulses can ensure the uniformity and controllability of material removal, and can be used to cope with more complex application scenarios.

[0046] Figure 4 This is a schematic diagram of the structure of another thrombus ablation catheter provided in this embodiment. Figure 4 , Figure 4 For Figure 3Cross-sectional view along the dashed line AA`.

[0047] See also Figure 3 and Figure 4 In this embodiment, the optical fiber driving unit 232 includes a driving motor, the transmission member 231 includes a transmission tube 2311, the inner surface of the transmission tube 231 has a plurality of protrusions 2312, and the surface of the protrusions 2312 is covered with a coating, and the coating includes a rubber coating.

[0048] In this embodiment, the transmission tube 231 and the catheter body 21 can be smoothed to reduce friction. Of course, multiple steel balls can be arranged between the transmission tube 231 and the catheter body 21 to reduce the friction between the transmission tube 231 and the catheter body 21.

[0049] In this embodiment, the protrusion 2312 is a thread.

[0050] In this embodiment, a plurality of protrusions are provided, and coatings are provided on the surfaces of the protrusions. The protrusions are connected to the optical fibers through the rubber coatings, and the optical fibers are driven to rotate through the friction between the rubber material and the surfaces of the optical fibers.

[0051] See also Figure 1 and Figure 4 In this embodiment, the Q-switched thulium laser thrombus ablation device further includes: The infusion component 3 includes an infusion unit 31 and an infusion pipeline 32 . The infusion pipeline 32 is the space between the protrusions 2312 .

[0052] In this embodiment, the infusion component 3 is used to deliver physiological saline or thrombolytic solution.

[0053] In this embodiment, the thrombolytic liquid is transferred by utilizing the gaps between the protrusions, and the gaps are evenly spaced and distributed, which is beneficial to the stability of liquid delivery.

[0054] In this embodiment, the infusion unit includes an infusion pump, through which the delivery amount of the liquid medicine can be accurately controlled.

[0055] In this embodiment, the Q-switched thulium laser treatment device has a first working mode and a second working mode; In the first working mode, a cavity is provided between the optical fiber 22 and the end of the catheter body 21 close to the thrombus, and the cavity is connected to the infusion line 32; In the second working mode, the optical fiber 22 is flush with the end of the catheter body 21 close to the thrombus.

[0056] In this embodiment, the position of the optical fiber is precisely controlled by the optical fiber drive assembly, and the distance from the thrombus lesion is controlled, and the dominant position of the photomechanical effect and the photoacoustic effect is adjusted by the change of the distance. When the photomechanical mode is the dominant mode (the photothermal mode also exists at this time, and the photothermal mode is the secondary mode), the optical fiber is adjusted to the inside of the catheter, with a cavity away from the end of the catheter, and physiological saline or thrombolytic agents are placed in the catheter. The laser-induced microjet acts on the embolic tissue, and the constraint of the catheter cavity can also enhance the water jet velocity, so that more energy is concentrated on the wavefront, and finally the thrombus is broken up; when the photothermal mode is the dominant mode, the optical fiber is flush with the end of the catheter, directly acting on the embolic position, and precise thermal ablation is achieved. For thinner blood vessel areas, the optical fiber can be extended outside the catheter alone to be close to the target tissue.

[0057] See also Figure 3 In this embodiment, the Q-switched thulium laser thrombus ablation device further includes: The expansion assembly 4 includes an expansion member driving unit 41 and an expansion member 42 . The expansion member 42 is disposed outside the catheter body 21 . The expansion member driving unit 41 is used to drive the expansion member 42 to expand or contract.

[0058] In this embodiment, the expansion member driving unit 41 may be a liquid infusion device or a gas infusion device, which is not limited in the present disclosure.

[0059] In this embodiment, the expansion member 42 is an expansion balloon.

[0060] In this embodiment, a delivery pipeline 43 is further provided between the expansion member driving unit 41 and the expansion member 42 .

[0061] In this embodiment, an expansion component is provided, and for mild embolism, the blood vessel can be expanded directly without activating the laser to eliminate the blockage. When the laser is activated, the balloon can expand the diameter of the blood vessel, increase the safe working space of the device, and avoid the problem of thermal stenosis of the blood vessel wall during the temperature rise of the laser.

[0062] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or make equivalent replacements for some of the technical features therein. However, these modifications or replacements do not deviate the essence of the corresponding technical solutions from the spirit and scope of the technical solutions of the embodiments of the present invention.

Claims

1. A Q-switched thulium laser thrombus ablation device, characterized in that: include: A Q-switched thulium laser generating component, used for generating a Q-switched thulium laser; A thrombus ablation catheter, comprising a catheter body, an optical fiber, and an optical fiber drive assembly; The optical fiber is arranged in the catheter body, and is used to obtain the Q-switched thulium laser and emit the Q-switched thulium laser toward the thrombus in the blood vessel; The optical fiber drive assembly includes a transmission member and an optical fiber drive unit. The transmission member is arranged between the catheter body and the optical fiber, and the transmission member is transmission-connected to the optical fiber. One end of the transmission member extends to the outside of the catheter body and is transmission-connected to the optical fiber drive unit.

2. The Q-switched thulium laser thrombus ablation device according to claim 1, characterized in that: The pulse width of the Q-switched thulium laser is 30-1000ns.

3. The Q-switched thulium laser thrombus ablation device according to claim 1, characterized in that: The repetition rate of the Q-switched thulium laser is 200 Hz to 200 kHz.

4. The Q-switched thulium laser thrombus ablation device according to claim 1, characterized in that: The average power of the Q-switched thulium laser is 0-30W.

5. The Q-switched thulium laser thrombus ablation device according to claim 1, characterized in that: The diameter of the movable optical fiber is 50-600 μm.

6. The Q-switched thulium laser thrombus ablation device according to any one of claims 1 to 5, characterized in that: The thulium laser generating device adopts a main oscillation power amplification structure, comprising: A seed light generating component and a laser amplifying component connected in sequence via thulium-doped optical fibers; The seed light generating component is used to generate the seed light of the thulium laser, and includes: A first grating and a second grating, an acousto-optic modulation device, a first laser and a first pump light stripping unit sequentially arranged between the first grating and the second grating, and a first laser isolation unit arranged behind the second grating, wherein the first laser isolation unit is used to control unidirectional transmission of seed light; The laser amplification component is used to amplify the seed light to form a thulium laser that meets the requirements, including: a plurality of second lasers coupled to the thulium-doped optical fiber, a second pump light stripping unit and a second laser isolation unit, wherein the second laser isolation unit is used to control the unidirectional transmission of the thulium laser.

7. The Q-switched thulium laser thrombus ablation device according to any one of claims 1 to 5, characterized in that: The optical fiber driving unit comprises a driving motor, the transmission member is a transmission tube, the inner surface of the transmission tube has a plurality of protrusions, the surface of the protrusions is covered with a coating, and the coating comprises a rubber coating.

8. The Q-switched thulium laser thrombus ablation device according to claim 7, characterized in that: The Q-switched thulium laser thrombus ablation device also includes: An infusion component comprises an infusion unit and an infusion pipeline, wherein the infusion pipeline is the gap between the protrusions.

9. The Q-switched thulium laser thrombus ablation device according to claim 8, characterized in that: The Q-switched thulium laser treatment device has a first working mode and a second working mode; In the first working mode, a cavity is provided between the optical fiber and the end of the catheter body close to the thrombus, and the cavity is connected to the infusion pipeline; In the second working mode, the optical fiber is flush with an end of the catheter body that is close to the thrombus.

10. The Q-switched thulium laser thrombus ablation device according to any one of claims 1 to 5, characterized in that: The Q-switched thulium laser thrombus ablation device further comprises: The expansion component comprises an expansion member driving unit and an expansion member, wherein the expansion member is arranged outside the catheter body, and the expansion member driving unit is used for driving the expansion member to expand or contract.

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