Rare ginsenoside nourishing paste and preparation method thereof

Abstract

The invention relates to a rare ginsenoside nourishing paste with the effects of tonifying and securing vital essence, protecting viscera and resisting aging and reviving and a preparation method thereof. The preparation method comprises the following steps: s101, crushing red ginseng, cornu cervi pantotrichum, radix rehmanniae preparata, herba cistanche, fructus lycii, fructus schizandrae and herba dendrobii by using a low-temperature freezing ultrafine grinder respectively to obtain medicinal powder, and mixing the medicinal powder to obtain mixed powder; s102, semen cuscutae, radix achyranthis bidentatae, radix astragali, radix aconiti carmichaeli preparata, radix asparagi, cortex cinnamomi, radix rehmanniae, cortex eucommiae, fructus psoraleae, halite, flos caryophylli, fructus amomi and radix glycyrrhizae are cut into fragments, the fragments are decocted with water and filtered, residues are removed, and liquid medicine is obtained. And s103, adding the superfine mixed powder obtained in the step s101, tortoise-plastron glue and red date powder into the liquid medicine obtained in the step s102, decocting, concentrating into paste, adding rare ginsenoside powder and honey, stirring, and carrying out hot canning. According to the invention, bold innovation is carried out by referring to a'tortoise age set 'prescription, the prescription is elaborately formulated, and particularly, the unique anti-aging functional factor'rare ginsenoside' is added and the strong seepage force of the nourishing paste is utilized, so that the effects of conditioning primordial qi, tonifying and securing essence, protecting viscera and resisting aging and reviving are achieved. Meanwhile, a modern low-temperature freezing and crushing technology is utilized to scientifically optimize a preparation process of the oral thick paste so as to increase the bioavailability of the medicine, and the red dates and the honey are utilized to moisten the mouth feel, so that the use compliance of eaters is greatly improved. And the method has very positive significance for practicing the idea of'preventive treatment of diseases' in the traditional Chinese medicine.

Description

Technical Field

[0001] The invention relates to the field of traditional Chinese medicine ointment, a rare ginsenoside tonic ointment and a preparation method thereof Background Art

[0002] Traditional Chinese medicine has unique advantages in prolonging life, resisting aging, and strengthening the body, showing the infinite wisdom of nature. The accumulated methods of medicine, food, acupuncture, physical therapy, and (external) exercises over thousands of years are vast and extremely rich, and many classic methods are unique.

[0003] As a traditional Chinese medicine with a history of more than 3,000 years, based on the principle of "diet therapy is the same as food therapy, and medicine and food are used together", it has been found in long-term life and medical practice that medicinal diet plays an extremely important role in promoting human health and longevity and preventing and treating diseases; and a unique medicinal diet treatment and health care theory has been formed.

[0004] As the main content of Chinese medicinal diet, paste prescriptions and nourishing pastes are the best choice for prolonging life and preventing and treating chronic diseases because of their four major advantages, including powerful therapeutic effects, deep conditioning, easy digestion, and sweet taste.

[0005] In traditional Chinese medicine, ginseng is the best traditional tonic in my country and the most widely used anti-aging Chinese medicine because of its effects of "replenishing vital energy, tonifying the spleen and lungs, promoting the production of body fluids and quenching thirst, calming the mind and improving intelligence". Modern pharmacological research has found that saponins in ginseng are the main functional factors involved in anti-aging, disease prevention and treatment. Through our research, we found that some of the rare ginsenosides have a significant effect on maintaining the vitality of longevity proteins, resisting telomere shortening, and maintaining metabolic stability.

[0006] "Guilingji" is derived from the royal health care secret book, and has been highly recommended by the Chinese medicine and health care community for 500 years. For hundreds of years, clinical trials have verified that "Guilingji" has real effects in strengthening the body and brain, adjusting nerves, promoting metabolism, and enhancing body vitality. Through inheritance and innovation, this recipe will play an extremely important role in "reinforcing essence, protecting internal organs, and resisting aging and returning to youth". Summary of the invention

[0007] The present invention provides a rare ginsenoside tonic paste and a preparation method thereof, comprising the following steps: S101, freeze-drying seven kinds of medicinal materials including red ginseng, pilose antler, prepared rehmannia root, cistanche deserticola, wolfberry fruit, schisandra chinensis, and dendrobium, and then grinding them by an ultrafine grinder to obtain mixed ultrafine powder (for example, the ultrafine powder has mesh sizes of 600, 900, 1200, 1500, 1800, 2100, 2400, and 2700); S102, forging Cuscuta, Achyranthes bidentata, Astragalus, Aconite, Asparagus cochinchinensis, Cinnamon bark, Radix Rehmanniae, Eucommia bark, Psoralea corylifolia, Green salt, Clove, Amomum villosum, Licorice into pieces and putting them into a cooking pot, adding water, heating to a high temperature (e.g., 95° C., 100° C., 105° C.), decocting (e.g., 6 h, 8 h, 10 h, 12 h), filtering, removing residues to obtain a medicinal solution; S103. Add the ultrafine powder, tortoise shell glue and red date powder obtained in S101 to the medicinal solution obtained in S102, boil and concentrate to make a paste. Finally, add rare ginsenosides (a mixture of aglycone protopanaxadiol and aglycone protopanaxadiol) and honey, stir, pass quality inspection and fill.

[0008] In parts by weight, the ingredients include 1-10 parts of red ginseng, 1-10 parts of pilose antler, 1-10 parts of cooked rehmannia, 1-10 parts of cistanche deserticola, 1-5 parts of dodder seeds, 1-5 parts of wolfberry fruits, 1-10 parts of cyperus rotundus, 1-5 parts of schisandra chinensis, 2-10 parts of dendrobium, 1-10 parts of astragalus, 1-10 parts of roasted aconite, 1-5 parts of asparagus, 1-5 parts of cinnamon, 1-10 parts of raw rehmannia, 1-5 parts of eucommia, 1-5 parts of psoralea corylifolia, 1-5 parts of green salt, 1-3 parts of cloves, 1-5 parts of amomum villosum, 1-3 parts of jujube, 1-3 parts of licorice, 1-5 parts of tortoise shell glue, 20-30 parts of red date powder, 5-15 parts of honey, and 1-2 parts of rare ginsenosides (a mixture of aglycone protopanaxadiol and aglycone protopanaxadiol).

[0009] In some optional embodiments of the present disclosure, in parts by weight, 10 parts of red ginseng, 3 parts of pilose antler, 6 parts of cooked rehmannia, 9 parts of cistanche, 3 parts of dodder seed, 3 parts of wolfberry, 6 parts of Chinese cyperus, 3 parts of schisandra, 10 parts of dendrobium, 6 parts of astragalus, 3 parts of roasted aconite, 3 parts of asparagus, 3 parts of cinnamon, 6 parts of raw rehmannia, 2 parts of eucommia, 3 parts of psoralea, 4 parts of green salt, 2 parts of cloves, 4 parts of amomum, 2 parts of jujube, 3 parts of licorice, 2 parts of tortoise shell glue, 20 parts of red date powder, 10 parts of honey, 1 part of rare ginsenoside (aglycone protopanaxadiol and aglycone protopanaxadiol are mixed in a ratio of 5:5) In some optional embodiments of the present disclosure, the amount of pure water used in step S103 is as follows: 10-16 times the total weight (e.g. 11 times, 12 times, 13 times, 14 times, 15 times, etc.).

[0010] In summary, the present disclosure has the following innovative effects: The present invention uses low-temperature freezing and crushing technology to grind the drug into ultrafine powder, which greatly improves the bioavailability of the drug and enhances its efficacy. In particular, by adding rare ginsenosides, relying on the strong penetration of the tonic paste to form a new drug composition, the "anti-aging and rejuvenation" effect of rare ginsenosides can be fully exerted. At the same time, the tonic paste uses red date powder and natural honey as flavoring agents to adjust the taste, greatly increasing the compliance of taking. Compared with other product dosage forms, the advantages are very obvious: Implementation

[0011] Prescription (weight ratio): 10 parts of red ginseng, 3 parts of velvet antler, 6 parts of cooked rehmannia, 9 parts of cistanche deserticola, 3 parts of dodder seed, 3 parts of wolfberry, 6 parts of cyperus rotundus, 3 parts of schisandra chinensis, 10 parts of dendrobium, 6 parts of astragalus, 3 parts of roasted aconite, 3 parts of asparagus, 3 parts of cinnamon, 8 parts of raw rehmannia, 2 parts of eucommia, 3 parts of psoralea corylifolia, 4 parts of green salt, 2 parts of cloves, 4 parts of amomum, 2 parts of jujube, 3 parts of liquorice, 2 parts of tortoise shell glue, 20 parts of red date powder, 10 parts of honey, 1 part of rare ginsenoside (aglycone protopanaxadiol and aglycone protopanaxadiol mixed in a ratio of 5:5) Preparation process: Step 1. 10 parts of red ginseng, 6 parts of pilose antler, 6 parts of cooked rehmannia, 9 parts of Cistanche deserticola, 3 parts of wolfberry, 3 parts of Schisandra chinensis, and 10 parts of Dendrobium are placed in a frozen low-temperature grinder and crushed, passed through a 600-mesh sieve, and then several superfine powders are mixed to obtain drug A; Step 2. Put 3 parts of Cuscuta, 6 parts of Achyranthes bidentata, 6 parts of Astragalus, 5 parts of Aconite, 3 parts of Asparagus cochinchinensis, 3 parts of Cinnamon bark, 8 parts of Rehmannia glutinosa, 2 parts of Eucommia bark, 3 parts of Psoralea corylifolia, 4 parts of Green Salt, 2 parts of Cloves, 4 parts of Amomum villosum, and 3 parts of Licorice into a decoction pot and wash them with pure water first, then add 15 times the total amount of the above medicinal materials with pure water, heat to 100 ° C, heat and decoct for 8 hours, filter and remove the residue to obtain liquid B; Step 3. First add liquid medicine B into the refining copper pot, add medicine A, 20 parts of red dates (powder), and 2 parts of tortoise shell glue in sequence while heating up, start the blender, raise the temperature and keep it below 75°C. When the liquid medicine becomes a paste, add 10 parts of honey and 1 part of rare ginsenoside, stop heating, stir for another 15 minutes, take samples for quality inspection, and if qualified, fill it to obtain the finished product.

Claims

1. A rare ginsenoside tonic paste and a preparation method thereof, comprising the following steps: s101. Freeze-dry red ginseng, pilose antler, prepared rehmannia root, cistanche deserticola, wolfberry, schisandra chinensis, and dendrobium officinale, and then grind them into a superfine grinder to obtain a mixed powder of medicinal materials. s102 Cut Cuscuta, Achyranthes bidentata, Astragalus, Aconite, Asparagus cochinchinensis, Cinnamon bark, Radix Rehmanniae, Eucommia bark, Psoralea corylifolia, Green salt, Clove, Amomum villosum, and Licorice into pieces, decoct in water, filter, and remove the residue to obtain a medicinal liquid. s103. Add the ultrafine powder, tortoise shell glue and red date powder obtained in s101 to the liquid medicine obtained in s102, boil and concentrate into paste, add rare ginsenoside powder and honey, stir and can. In parts by weight, the following ingredients include 2-10 parts of red ginseng, 1-10 parts of pilose antler, 1-10 parts of cooked rehmannia, 1-10 parts of cistanche deserticola, 1-5 parts of dodder seeds, 1-5 parts of wolfberry, 1-10 parts of cyperus rotundus, 1-5 parts of schisandra chinensis, 2-10 parts of dendrobium, 1-10 parts of astragalus, 1-10 parts of roasted aconite, 1-5 parts of asparagus, 1-5 parts of cinnamon, 1-10 parts of raw rehmannia, 1-5 parts of eucommia, 1-5 parts of psoralea corylifolia, 1-5 parts of green salt, 1-3 parts of cloves, 1-5 parts of amomum villosum, 1-3 parts of jujube, 1-3 parts of licorice, 1-5 parts of tortoise shell glue, 5-10 parts of red date powder, 5-15 parts of honey, and 1-2 parts of rare ginsenosides.

2. The preparation method according to claim 1, characterized in that: In step s101, the ultrafine powder is between 300 and 3000 meshes.

3. According to the requirements, the rare ginsenoside is a combination of the following two ginsenosides: Aglycone PPD (aPPD), aglycone PPT (aPPT), among which, The weight ratio of the aglycone protopanaxadiol to the aglycone protopanaxantriol is (1∽15):

5.

4. The preparation method according to claim 1, in said s102, the conditions for decocting with water include: the amount of water added is 10-16 times the total amount of medicinal materials, the temperature is 95-105°C, and the time is 6-12 hours.

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