Integrated particle preparation device combining ball-milling crushing and fluidized bed drying

Abstract

The invention belongs to the technical field of medicine granulation, particularly relates to an integrated particle preparation device combining ball-milling crushing and fluidized bed drying, and provides the following scheme aiming at the problems that raw materials are polluted by external bacteria and viruses and dust can block a dust removal bag in the existing transportation process: the integrated particle preparation device comprises a frame body, the device comprises a frame body, a crushing cylinder is rotatably arranged at the top of the frame body, a plurality of steel balls are arranged in the crushing cylinder, the crushing cylinder is matched with the steel balls to crush raw materials, a drying cylinder is arranged on one side of the frame body, and an air inlet cylinder is fixed to the bottom of the drying cylinder. In addition, during drying and granulation, the dust removal cloth bag can be driven to shake through operation of the smashing cylinder, dust attached to the interior of the dust removal cloth bag is removed, waste of the raw materials is avoided, the dust removal cloth bag can continue to conduct exhausting and filtering operation, and smooth operation of drying and granulation is guaranteed.

Description

Technical Field

[0001] The invention relates to the field of pharmaceutical granulation, and in particular to an integrated granule preparation device combining ball milling and fluidized bed drying. Background Art

[0002] The particle preparation device has a wide range of application prospects in the chemical, pharmaceutical, food and other industries. When preparing particles, the raw materials need to be crushed and then dried and granulated.

[0003] The prior art still has the following disadvantages when granulating: 1. During granulation, the raw materials need to be crushed and then transported to the drying equipment for drying and granulation. However, during the transportation process, the raw materials are inevitably exposed to the outside world, causing bacteria and viruses from the outside world to contaminate the raw materials, resulting in quality problems in the later granulation products; 2. During the drying and granulation process, the dust carried in the dried air needs to be filtered through a dust bag to avoid pollution of the outside air. However, after the dust bag has been used for a long time, the dust will clog the dust bag, resulting in the internal gas being unable to be discharged to the outside smoothly, thereby affecting the preparation of the particles.

[0004] In view of the above problems, the present invention document proposes an integrated particle preparation device combining ball milling and fluidized bed drying. Summary of the invention

[0005] The purpose of the present invention is to solve the shortcomings of raw materials being contaminated by external bacteria and viruses during transportation and dust clogging dust removal bags, and to propose an integrated particle preparation device combining ball milling and fluidized bed drying.

[0006] In order to achieve the above object, the present invention adopts the following technical solutions: An integrated particle preparation device combining ball milling and fluidized bed drying, comprising a frame, a pulverizing cylinder is rotatably provided on the top of the frame, and a plurality of steel balls are provided in the pulverizing cylinder, and the pulverizing cylinder and the steel balls cooperate to pulverize the raw materials, a drying cylinder is provided on one side of the frame, an air inlet cylinder is fixed at the bottom of the drying cylinder, and the drying cylinder and the air inlet cylinder are connected through a plurality of air injection holes, and are used to inject dry hot air into the drying cylinder to dry the raw materials; It also includes two fixed cylinders, the bottom ends of the two fixed cylinders are fixed to the top of the drying cylinder and are connected to the drying cylinder, and are used to discharge the hot air with moisture in the drying cylinder. The two fixed cylinders are provided with dust bags for filtering dust in the hot air. The crushing structure is arranged on the top of the frame and is used to drive the crushing cylinder to rotate to complete the crushing of the raw materials; The material conveying structure is arranged between the crushing cylinder and the drying cylinder, and is used to convey the crushed raw materials in the crushing cylinder to the drying cylinder; The drying and granulating structure is arranged in the drying cylinder and the air inlet cylinder and is used to dry and granulate the raw materials; The shaking structure is arranged between the fixed cylinder and the drying cylinder, and is used for alternately shaking the two dust removal bags to discharge the dust on them back into the drying cylinder, and the crushing structure can provide driving force for the shaking structure.

[0007] In a possible design, the crushing structure includes a support seat fixed on the top of the frame, and a first rotating shaft and a second rotating shaft are respectively fixed at both ends of the crushing barrel, one end of the first rotating shaft rotates and penetrates the support seat, so as to make the rotation of the crushing barrel more stable, a gear ring is fixed on the end of the crushing barrel close to the first rotating shaft, a second motor is fixed on the top of the frame, the output shaft of the second motor rotates and penetrates the support seat and is fixed with a first gear, and the first gear is meshed with the gear ring, a feed pipe is fixedly connected to one side of the top of the crushing barrel, and a discharge pipe is fixedly connected to one side of the bottom of the crushing barrel, and a screen plate is fixed in the discharge pipe for screening the crushed raw materials; solid raw materials are injected into the crushing barrel through the feed pipe, and the second motor drives the crushing barrel to rotate through the cooperation of the first gear and the gear ring, and the crushing barrel drives the raw materials and steel balls inside it to rotate, and the raw materials are crushed by the impact force of the steel balls falling from a high place, and the raw materials in the crushing barrel can be discharged to the outside through the discharge pipe, and the screen plate can screen the raw materials.

[0008] The cam is an angular channel that is adapted to move the load sheathing of the roll-tops toward the loadsheet, the cam being arranged on a line with the center of the roll-tops being adapted to move the loadsheet against the loadsheet when the roll-tops are in contact with the loadsheet. The chute is provided with a Z-shaped rod which is slidably connected in the first slide and the second slide, one end of the Z-shaped rod extends into the feed hopper and is fixedly connected to the return plate, one end of the Z-shaped rod extends into the drying cylinder and is fixedly connected to the closing plate, and the closing plate is used to close the feed hopper, and an electric push rod is fixed on one side of the drying cylinder, and the output shaft of the electric push rod is fixedly connected to the Z-shaped rod, which is used to synchronously drive the return plate and the closing plate to move up, and the return plate moves up and cooperates with the discharge pipe to avoid the raw materials from contacting external bacteria during discharge; the electric push rod drives the return plate and the closing plate to move up synchronously through the Z-shaped rod, and the closing plate releases the sealing of the feed hopper, and the return plate moves up and fits the bottom of the crushing cylinder to connect the crushing cylinder with the feed hopper, and when the return plate moves up, the rotating plate is driven to rotate through the cooperation of the rack and the second gear to release the sealing of the discharge pipe, and the raw materials crushed in the crushing cylinder enter the feed hopper through the screening of the sieve plate and are injected into the drying cylinder, so as to avoid the raw materials from contacting external bacteria during discharge, thereby ensuring the quality of the medicine after drying and granulation in the later stage.

[0009] In a possible design, the drying granulation structure includes a stirring shaft rotating on the inner wall of the bottom of the drying cylinder, a partition is fixed in the drying cylinder, a plurality of fine holes are provided in the partition, and the hot air in the air inlet cylinder flows upward, and the top end of the stirring shaft rotates to penetrate the partition, a plurality of stirring blades are fixed on the outer wall of the stirring shaft, and a plurality of stirring blades are provided on one side to make the raw materials move upward along the inclined surface when stirring the raw materials, a liquid storage ring is fixed in the drying cylinder, a plurality of atomizing nozzles are fixed in the liquid storage ring, and an injection pipe connected to the liquid storage ring is fixed on one side of the drying cylinder, and the end of the injection pipe away from the liquid storage ring is connected to the liquid raw material storage tank outside. The two parts are connected and used to inject liquid raw materials into the drying cylinder; hot air is injected into the drying cylinder through the air injection hole, and the raw materials in the drying cylinder are blown upward and boiled, and the boiling of the raw materials in the drying cylinder can increase the contact area between the raw materials and the hot air, so that the raw materials are fully dried, and the motor drives the stirring shaft and the stirring blades to rotate, and the inclined surface of the stirring blades can scrape the raw materials upward, so that the raw materials can move upward under the action of the dry air, and in addition, the liquid raw materials are injected into the liquid storage ring through the injection pipe, and the liquid raw materials are atomized and sprayed into the raw materials in the drying cylinder through the atomizing nozzle, so that the liquid raw materials are mixed with the powdered raw materials to form particles, and when the liquid raw materials wrap the powdered raw materials, the hot air can dry the particles.

[0010] In a possible design, the shaking structure includes two fixing rings, the two fixing rings are respectively fixed in the two fixing cylinders, the bottom ends of the two dust bags are respectively fixedly connected to the tops of the two fixing rings, a first top plate is fixed to the tops of the two dust bags, a lifting plate is sealingly and slidably connected in the two fixing cylinders, the bottoms of the two lifting plates are respectively fixedly connected to the tops of the two first top plates for driving the dust bags to shake, a second top plate is provided on the tops of the two fixing cylinders, a plurality of fixing rods are slidably penetrated in the two second top plates, and a plurality of fixing rods located in the same second top plate are fixed to the tops of the corresponding fixing cylinders, a plurality of first springs are fixed between the bottom of the second top plate and the top of the fixing cylinder, and the first springs are sleeved on the outside of the fixing rods The two L-shaped exhaust pipes are fixedly passed through the wall, and the bottom ends of the two L-shaped exhaust pipes are fixedly passed through the corresponding lifting plates, and the lifting plates are driven to move back and forth up and down through the cooperation of the second top plate and the L-shaped exhaust pipe; the hot air carrying moisture is discharged to the outside through the fixed cylinder and the L-shaped exhaust pipe, and the dust bag can filter the dust raw materials in the hot air to avoid the dust discharge to the outside causing air pollution and waste of raw materials. After the dust bag has filtered the air for a certain period of time, the rotating disk drives the corresponding connecting rod and the second top plate to reciprocate and rise and fall through the cooperation of the pin shaft and the lifting frame, and then the dust bag is driven to shake through the cooperation of the second top plate, the L-shaped exhaust pipe and the lifting plate, so as to shake off the dust attached to the dust bag, so that it can enter the drying cylinder again for granulation, thereby avoiding waste of raw materials.

[0011] The cam is connected with the second end of the second rotating shaft to move ... A second spring is fixed on the side of the iron blocks that are away from each other, and the two second springs are respectively fixed in the corresponding sliding grooves; when the dust bag has filtered the air for a certain period of time, the corresponding electromagnet is energized and the other electromagnet is de-energized. The magnetic attraction of the electromagnet on the iron block is greater than the pulling force of the second spring. At this time, the electromagnet sucks the corresponding iron block out of the sliding groove, and then the iron block previously located under the lifting frame shrinks to the sliding groove under the action of the second spring after losing the magnetic attraction of the other electromagnet. In the process of the crushing cylinder driving the rotating disk to rotate through the second rotating shaft, the rotating disk drives the corresponding connecting rod and the second top plate to reciprocate and rise and fall through the cooperation of the pin shaft and the lifting frame, and then the dust bag is driven to shake through the cooperation of the second top plate, the L-shaped exhaust pipe and the lifting plate, so as to shake off the dust attached to the dust bag, so that it can enter the drying cylinder again for granulation, thereby avoiding waste of raw materials.

[0012] In one possible design, the bottom of the air intake cylinder is fixedly connected to an air intake pipe, which is connected to an external dry hot air source through a hose. One side of the drying cylinder is fixedly connected to a discharge pipe, and the top of the discharge pipe is fixedly passed through a partition. The outer walls of the discharge pipe and the air intake pipe are both provided with solenoid valves.

[0013] In a possible design, the magnetic attraction between the iron stopper and the electromagnet is greater than the pulling force of the second spring, which is used to pull the iron stopper out of the sliding slot and move it to the bottom of the lifting frame.

[0014] In a possible design, the torsion force of the torsion spring is greater than the gravity of the rotating plate, so as to reset the rotating plate and rotate it to close the discharge pipe when the rack is disengaged from the second gear.

[0015] In a possible design, the inner walls of the two sides of the crushing barrel that are away from each other are rotatably connected to the third rotating shaft, and the outer walls of the two third rotating shafts are fixed with multiple connecting frames, and one end of the two corresponding connecting frames on the two third rotating shafts is fixed with the same scraper for stirring the steel balls and raw materials in the crushing barrel, and one end of the third rotating shaft close to the support seat rotates and passes through the first rotating shaft, and a first motor is fixed to one side of the support seat through a frame, and the output shaft of the first motor is fixedly connected to one end of the third rotating shaft; the scraper is driven to rotate by the cooperation of the third rotating shaft and the connecting frame, and the scraper scrapes the raw materials and steel balls in the crushing barrel, which can not only stir the raw materials in the crushing barrel but also enable the steel balls to crush the raw materials again when the crushing barrel is stationary. In addition, the scraper can accelerate the discharge of the raw materials from the discharge pipe when stirring.

[0016] Beneficial effect: In the present invention, two rotating plates for closing the discharge pipe are provided at the bottom of the discharge pipe, the two rotating plates are respectively fixedly connected to the two rotating rods, the outer walls of the two rotating rods are fixedly sleeved with a second gear, a return plate is slidably connected in the feed hopper, the inner walls on both sides of the return plate away from each other are fixed with racks, and the two ends of the Z-shaped rod are respectively fixedly connected to the return plate and the closing plate; the return plate and the closing plate move up synchronously, and when the return plate moves up, the rotating plate is driven to rotate by the cooperation of the rack and the second gear to release the sealing of the discharge pipe, and the raw materials in the crushing cylinder are injected into the drying cylinder through the feed hopper, so as to avoid the raw materials from contacting external bacteria during discharge, thereby ensuring the quality of the medicine after drying and granulation in the later stage; In the present invention, a lifting plate is sealingly and slidably connected in the fixed cylinder, the bottom of the lifting plate is fixedly connected to the top of the first top plate, the top of the fixed cylinder is slidably provided with a second top plate through a fixed rod, an L-shaped exhaust pipe is fixedly passed through the second top plate, and the bottom end of the L-shaped exhaust pipe is fixedly passed through the lifting plate; the dust bag can filter the dust raw materials in the hot air to avoid air pollution and waste of raw materials, and the rotating disk drives the corresponding connecting rod and the second top plate to reciprocate and lift through the cooperation of the pin shaft and the lifting frame, and then the dust bag is driven to shake through the cooperation of the second top plate, the L-shaped exhaust pipe and the lifting plate, so as to shake off the dust attached to the dust bag, so that it can enter the drying cylinder again for granulation to avoid waste of raw materials; In the present invention, a pin shaft is slidably fitted in the lifting frame, one end of the pin shaft is fixed to a side of the rotating disk deviating from the center of the circle, and electromagnets are fixed on both sides of the bottom of the lifting frame. The sides of the two connecting rods close to each other are respectively slidably fitted with the two ends of the lifting frame, and the sides of the two connecting rods close to each other are slidably connected with iron blocks through sliding grooves; the corresponding electromagnets are powered on and off, which can control the corresponding iron blocks to move out of the sliding grooves, and then cooperate with the lifting frame to drive the two connecting rods to rise and fall alternately, thereby controlling the two dust bags to shake alternately, shaking off the dust attached to the dust bags, so that they can enter the drying cylinder again for granulation, thereby avoiding waste of raw materials.

[0017] In the present invention, after the raw materials are crushed, they are automatically transported to the drying cylinder, and the raw materials are prevented from being contaminated by external bacteria during the transportation process. In addition, during drying and granulation, the dust removal bag can be driven to shake through the operation of the crushing cylinder to remove the dust attached to the dust removal bag, which not only avoids the waste of raw materials, but also enables the dust removal bag to continue to perform exhaust and filtering operations, thereby ensuring the smooth operation of drying and granulation. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 A schematic diagram of the three-dimensional structure of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 2 A schematic diagram of a three-dimensional exploded cross-sectional structure of a feed pipe, a first motor and a return plate of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 3 A schematic three-dimensional cross-sectional structure diagram of a feed hopper and a discharge pipe of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 4 A schematic diagram of a three-dimensional exploded cross-sectional structure of a return plate, a rotating rod and a rotating plate of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 5 A schematic three-dimensional cross-sectional structure diagram of a drying cylinder and an air inlet cylinder of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 6 A schematic diagram of a three-dimensional exploded structure of a fixed cylinder, a connecting rod and a lifting frame of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 7 A schematic diagram of a three-dimensional cross-sectional structure of a second top plate and a fixed cylinder of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Figure 8 A schematic diagram of a three-dimensional explosion structure of a lifting plate, a dust removal bag and a fixing ring of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Fig. 9 A schematic diagram of a three-dimensional explosion structure of a connecting rod, a lifting frame and an iron block of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 1 of the present invention; Fig.10 A schematic diagram of a three-dimensional cross-sectional structure of a grinding cylinder and a support seat of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 2 of the present invention; Fig.11 This is a schematic diagram of the three-dimensional structure of a scraper and a third rotating shaft of an integrated particle preparation device combining ball milling and fluidized bed drying provided in Example 2 of the present invention.

[0019] In the figure: 1, frame; 2, crushing cylinder; 3, drying cylinder; 4, first motor; 5, feed pipe; 6, discharge pipe; 7, sieve plate; 8, support seat; 9, first rotating shaft; 10, second rotating shaft; 11, gear ring; 12, second motor; 13, first gear; 14, feed hopper; 15, first chute; 16, second chute; 17, return plate; 18, closing plate; 19, Z-shaped rod; 20, electric push rod; 21, rack; 22, base; 23, rotating rod; 24, rotating plate; 25, torsion spring; 26, second gear; 27, air inlet cylinder; 28, air injection hole; 29, air inlet pipe; 3 0. Partition; 31. Stirring shaft; 32. Stirring blade; 33. Discharge pipe; 34. Liquid storage ring; 35. Atomizing nozzle; 36. Injection pipe; 37. Fixed cylinder; 38. Fixed ring; 39. Dust bag; 40. First top plate; 41. Lifting plate; 42. Second top plate; 43. L-shaped exhaust pipe; 44. Fixed rod; 45. First spring; 46. Rotating disk; 47. Pin; 48. Lifting frame; 49. Sliding rod; 50. Connecting rod; 51. Sliding groove; 52. Iron stopper; 53. Second spring; 54. Electromagnet; 55. Third rotating shaft; 56. Connecting frame; 57. Scraper. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be described clearly and completely below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments.

[0021] Example 1: Reference Figure 1 and Figure 2The granule preparation device relates to the field of pharmaceutical granulation. The device comprises a frame 1. A crushing cylinder 2 is rotatably arranged on the top of the frame 1. A plurality of steel balls are arranged in the crushing cylinder 2. The steel balls cooperate with the crushing cylinder 2 to crush the raw materials. A drying cylinder 3 is arranged on one side of the frame 1 to dry the crushed raw materials.

[0022] Reference Figure 1 and Figure 5 At the bottom of the drying cylinder 3, an air inlet cylinder 27 is fixed, and the air inlet cylinder 27 is connected to the drying cylinder 3 through a plurality of air injection holes 28. In this way, dry hot air can be injected into the drying cylinder 3 through the air inlet cylinder 27 to dry the raw materials.

[0023] Reference Figure 1 and Figure 7 In order to discharge the hot air with moisture in the drying cylinder 3, two fixed cylinders 37 are provided, the bottom ends of which are fixed to the top of the drying cylinder 3 and are connected to the drying cylinder 3. A dust bag 39 is provided in each fixed cylinder 37 to filter the dust in the discharged hot air to prevent the dust from polluting the environment.

[0024] Reference Figure 1 and Figure 2 In order to achieve the crushing of raw materials, a crushing structure is provided. The structure includes a support seat 8 fixed on the top of the frame 1, and a first rotating shaft 9 and a second rotating shaft 10 are respectively fixed at both ends of the crushing barrel 2. One end of the first rotating shaft 9 rotates through the support seat 8, so that the crushing barrel 2 rotates more stably. A gear ring 11 is fixed to the end of the crushing barrel 2 close to the first rotating shaft 9. A second motor 12 is also fixed on the top of the frame 1, and its output shaft rotates through the support seat 8 and is fixed with a first gear 13, which is meshed with the gear ring 11. In this way, the second motor 12 can drive the crushing barrel 2 to rotate through the cooperation of the first gear 13 and the gear ring 11, thereby completing the crushing of the raw materials. A feed pipe 5 is fixedly connected to one side of the top of the crushing barrel 2 for injecting raw materials into the crushing barrel 2. A discharge pipe 6 is fixedly connected to one side of the bottom of the crushing barrel 2, and a sieve plate 7 is fixed in the discharge pipe 6 for screening the crushed raw materials to ensure that only particles that meet the requirements can enter the next process.

[0025] Reference Figure 1-Figure 5In order to transfer the crushed raw materials into the drying cylinder 3, a feeding structure is provided. The structure includes a feed hopper 14 fixed on one side of the drying cylinder 3, the feed hopper 14 is connected to the drying cylinder 3, and is located below the discharge pipe 6. Two bases 22 are fixed on both sides of the discharge pipe 6, and the same rotating rod 23 is rotatably penetrated in the two bases 22 on the same side. Two rotating plates 24 are provided at the bottom of the discharge pipe 6 for closing the discharge pipe 6. The two rotating plates 24 are fixedly connected to the two rotating rods 23 respectively. The outer walls of the two rotating rods 23 are each sleeved with two torsion springs 25, one end of the torsion spring 25 is fixedly connected to the base 22, and the other end is fixedly connected to the rotating plate 24, which is used to keep the rotating plate 24 in a closed state to the discharge pipe 6. The outer walls of the two rotating rods 23 are also fixedly sleeved with a second gear 26. A return plate 17 is slidably connected in the feed hopper 14, and racks 21 are fixed to the inner walls on both sides of the return plate 17, and the racks 21 are meshed with the second gear 26. When the return plate 17 moves upward, the cooperation between the rack 21 and the second gear 26 can drive the rotating plate 24 to rotate, thereby releasing the blockage of the discharge pipe 6. In addition, a first chute 15 and a second chute 16 are respectively provided on the side where the feed hopper 14 and the drying cylinder 3 are close to each other, and the same Z-shaped rod 19 is slidably connected in the first chute 15 and the second chute 16. One end of the Z-shaped rod 19 extends into the feed hopper 14 and is fixedly connected to the return plate 17, and the other end extends into the drying cylinder 3 and is fixedly connected to the closing plate 18. The closing plate 18 is used to close the opening of the feed hopper 14. An electric push rod 20 is fixed on one side of the drying cylinder 3, and its output shaft is fixedly connected to the Z-shaped rod 19.

[0026] When the electric push rod 20 is working, it can drive the Z-shaped rod 19, the return plate 17 and the closing plate 18 to move upward synchronously. In this way, the closing plate 18 can release the seal of the feed hopper 14, and the return plate 17 can move up to fit the bottom of the crushing cylinder 2, connecting the crushing cylinder 2 with the feed hopper 14. At the same time, when the return plate 17 moves up, it can also drive the rotating plate 24 to rotate, releasing the seal of the discharge pipe 6. In this way, the raw materials crushed in the crushing cylinder 2 can enter the feed hopper 14 through the screening of the sieve plate 7, and finally be injected into the drying cylinder 3.

[0027] Reference Figure 4 , the torsion force of the torsion spring 25 is set to be greater than the weight of the rotating plate 24. This means that after the rack 21 is disengaged from the second gear 26, the torsion force of the torsion spring 25 will be sufficient to reset the rotating plate 24 and thus close the discharge pipe 6. This design ensures that the discharge pipe 6 will remain closed when there is no external force, preventing accidental leakage of particles.

[0028] Reference Figure 5A drying and granulating structure is also provided in the drying cylinder 3 and the air inlet cylinder 27 for drying and granulating the raw materials. The drying and granulating structure includes a stirring shaft 31 rotatably mounted on the inner wall at the bottom of the drying cylinder 3, and the stirring shaft 31 can be driven to rotate by a motor. A partition 30 is fixed in the drying cylinder 3, and a plurality of fine holes are provided on the partition 30, which allow hot air to flow upward from the air inlet cylinder 27. The top end of the stirring shaft 31 rotates through the partition 30, and a plurality of stirring blades 32 are fixed on the outer wall of the stirring shaft 31, and a slope is provided on one side of the stirring blades 32 so that the raw materials can move upward along the slope when stirring the raw materials. In addition, a liquid storage ring 34 is also fixed in the drying cylinder 3, and a plurality of atomizing nozzles 35 are installed in the liquid storage ring 34. An injection pipe 36 is fixedly passed through one side of the drying cylinder 3 . The injection pipe 36 is connected to the liquid storage ring 34 . One end of the injection pipe 36 away from the liquid storage ring 34 is connected to the external liquid raw material bin for injecting liquid raw material into the drying cylinder 3 .

[0029] When hot air is injected into the drying cylinder 3 through the air injection hole 28, the raw materials in the drying cylinder 3 will be blown upward and made to boil, thereby increasing the contact area between the raw materials and the hot air, so that the raw materials can be fully dried. At the same time, the motor drives the stirring shaft 31 and the stirring blade 32 to rotate, and the inclined surface of the stirring blade 32 scrapes the raw materials upward, so that the raw materials move upward under the action of the dry air. In addition, the liquid raw material is injected into the liquid storage ring 34 through the injection pipe 36, and is sprayed into the raw materials in the drying cylinder 3 by the atomizing nozzle 35, so that the liquid raw material is mixed with the powdered raw material to form particles, and when the liquid raw material wraps the powdered raw material, the hot air can dry the particles.

[0030] Reference Figure 5 , an air inlet pipe 29 is fixedly connected to the bottom of the air inlet cylinder 27. The air inlet pipe 29 is connected to an external dry hot air source through a hose to ensure that the hot air can smoothly enter the air inlet cylinder 27. On one side of the drying cylinder 3, a discharge pipe 33 is fixedly connected, and the top of the discharge pipe 33 is fixedly penetrated through the partition 30. Such a design allows the particles that have been dried to be discharged smoothly from the discharge pipe 33. At the same time, in order to ensure accurate control of the flow of gas and particles, solenoid valves are installed on the outer walls of the discharge pipe 33 and the air inlet pipe 29. By controlling the opening and closing of these solenoid valves, the flow of gas and particles can be accurately controlled.

[0031] Reference Figure 1 , Figure 7 and Figure 8In order to alternately shake the two dust bags 39 and discharge the dust on them back into the drying cylinder 3, a shaking structure is provided. This structure can use the second motor 12 in the crushing structure as a driving force. The shaking structure is included in a fixed cylinder 37 where two fixed rings 38 are respectively fixedly installed, and the bottom ends of the two dust bags 39 are respectively fixedly connected to the tops of the two fixed rings 38. The tops of the two dust bags 39 are fixed with a first top plate 40, and the two fixed cylinders 37 are sealed and slidably connected with a lifting plate 41. The bottoms of the two lifting plates 41 are respectively fixedly connected to the tops of the two first top plates 40, so that the dust bags 39 can be driven to shake. The tops of the two fixed cylinders 37 are provided with a second top plate 42, and a plurality of fixed rods 44 are slidably penetrated in the second top plate 42, and these fixed rods 44 are fixed to the tops of the corresponding fixed cylinders 37. A plurality of first springs 45 are fixed between the bottom of the second top plate 42 and the top of the fixed cylinder 37, and the first springs 45 are sleeved on the outer wall of the fixed rod 44. An L-shaped exhaust pipe 43 is fixedly passed through each of the two second top plates 42, and the bottom end of the L-shaped exhaust pipe 43 is fixedly passed through the corresponding lifting plate 41. When the hot air carrying moisture is discharged to the outside through the fixed cylinder 37 and the L-shaped exhaust pipe 43, the dust removal bag 39 will filter the dust raw materials in the hot air to prevent the dust from being discharged to the outside, causing air pollution and waste of raw materials.

[0032] Reference Figure 2 , Figure 6 , Figure 7 and Fig. 9 , further, the shaking structure also includes a rotating disk 46 located between the two fixed cylinders 37, and the rotating disk 46 is fixedly connected to the end of the second rotating shaft 10 away from the crushing cylinder 2. The top of the drying cylinder 3 is sealed and slidably penetrated by a sliding rod 49, and a lifting frame 48 is fixed to the top of the sliding rod 49. A pin 47 is slidably matched in the lifting frame 48, and one end of the pin 47 is fixed to the side of the rotating disk 46 that deviates from the center of the circle. Electromagnets 54 are fixed on both sides of the bottom of the lifting frame 48, and connecting rods 50 are fixed on the sides where the two second top plates 42 are close to each other, and the connecting rods 50 are slidably matched with the lifting frame 48. A sliding groove 51 is provided on the connecting rod 50, and an iron block 52 is slidably connected in the sliding groove 51, and a magnetic attraction can be generated between the iron block 52 and the electromagnet 54. The iron block 52 cooperates with the lifting frame 48, so that the lifting frame 48 can drive the connecting rod 50 and the second top plate 42 to move downward. A second spring 53 is fixed to a side of the iron stopper 52 away from the sliding slot 51 , and the second spring 53 is fixed in the sliding slot 51 .

[0033] After the dust bag 39 has filtered the air for a certain period of time, the corresponding electromagnet 54 is powered on to generate magnetism, attracting the iron block 52, while the other electromagnet 54 is powered off and loses its magnetism. At this time, the magnetic attraction of the energized electromagnet 54 on the iron block 52 is greater than the pulling force of the second spring 53, and the corresponding iron block 52 is sucked out of the sliding groove 51. After losing the magnetic attraction of the other electromagnet 54, the iron block 52 previously located under the lifting frame 48 shrinks into the sliding groove 51 under the action of the second spring 53. In the process of the crushing barrel 2 driving the rotating disk 46 to rotate through the second rotating shaft 10, the rotating disk 46 drives the corresponding connecting rod 50 and the second top plate 42 to reciprocate and rise and fall through the cooperation of the pin shaft 47 and the lifting frame 48. Then, through the cooperation of the second top plate 42, the L-shaped exhaust pipe 43 and the lifting plate 41, the dust bag 39 is driven to shake, and the dust attached to the dust bag 39 is shaken off, so that it can enter the drying cylinder 3 again for granulation, avoiding the waste of raw materials.

[0034] Reference Fig. 9 , the magnetic attraction between the iron stopper 52 and the electromagnet 54 is set to be greater than the pulling force of the second spring 53. This means that when the electromagnet 54 is activated, it can overcome the pulling force of the second spring 53, pull the iron stopper 52 out of the sliding slot 51, and move it to the bottom of the lifting frame 48. Such a design allows the position of the iron stopper 52 to be controlled by activating the electromagnet 54 when necessary, thereby achieving a specific function.

[0035] In summary, this integrated particle preparation device that combines ball milling and fluidized bed drying realizes the integrated operation of raw material crushing, drying and particle preparation through ingenious design, and has the function of shaking the dust removal bag to clean the attached dust, thereby improving the utilization rate of raw materials, preparation efficiency and product quality.

[0036] Example 2: Reference Fig.10 and Fig.11 , improved on the basis of Example 1: On the inner walls of both sides of the crushing barrel 2, a third rotating shaft 55 is rotatably connected. A plurality of connecting frames 56 are fixed on the outer wall of each third rotating shaft 55, and one end of the two corresponding connecting frames 56 on the two third rotating shafts 55 is fixedly connected with a scraper 57. Such a design makes it possible for the scraper 57 to rotate when the third rotating shaft 55 rotates, thereby stirring the steel balls and raw materials in the crushing barrel 2. One end of the third rotating shaft 55 close to the support seat 8 rotates and passes through the first rotating shaft 9, and a first motor 4 is fixed to one side of the support seat 8 through the frame. The output shaft of the first motor 4 is fixedly connected to one end of the third rotating shaft 55.

[0037] When the first motor 4 is started, it drives the third rotating shaft 55 to rotate, and then drives the scraper 57 to rotate through the connecting frame 56. The rotation of the scraper 57 can not only stir the raw materials and steel balls in the crushing cylinder 2, but also accelerate the discharge of the raw materials from the discharge pipe 6. In addition, when the crushing cylinder 2 is stationary, the scraper 57 can still further crush the raw materials through the rolling of the steel balls.

[0038] A method for using an integrated particle preparation device combining ball milling and fluidized bed drying comprises the following steps: S1. Solid raw materials are injected into the crushing drum 2 through the feed pipe 5. The second motor 12 drives the crushing drum 2 to rotate through the cooperation of the first gear 13 and the gear ring 11. The crushing drum 2 drives the raw materials and steel balls inside it to rotate, and the raw materials are crushed by the impact force of the steel balls falling from a high place; S2. After the raw material is crushed, the discharge pipe 6 is just located above the return plate 17. The electric push rod 20 drives the return plate 17 and the closing plate 18 to move up synchronously through the Z-shaped rod 19. The closing plate 18 releases the seal on the feed hopper 14. The return plate 17 moves up and fits with the bottom of the crushing cylinder 2, connecting the crushing cylinder 2 with the feed hopper 14. When the return plate 17 moves up, the rack 21 and the second gear 26 drive the rotating plate 24 to rotate, and the seal on the discharge pipe 6 is released. The crushed raw material in the crushing cylinder 2 enters the feed hopper 14 through the screening of the sieve plate 7 and is injected into the drying cylinder 3, so as to avoid the raw material from contacting external bacteria during discharge, thereby ensuring the quality of the medicine after drying and granulation in the later stage. S3. In addition, the scraper 57 is driven to rotate by the cooperation of the third rotating shaft 55 and the connecting frame 56. The scraper 57 scrapes the raw materials and the steel balls in the crushing tube 2, which can not only stir the raw materials in the crushing tube 2 but also make the crushing tube 2 stop and allow the steel balls to crush the raw materials again. In addition, the scraper 57 can accelerate the discharge of the raw materials from the discharge pipe 6 when stirring; S4. After the raw material enters the drying cylinder 3, the closing plate 18 recloses the feed hopper 14, and then dry hot air is injected into the air inlet cylinder 27 through the air inlet pipe 29, and the hot air is injected into the drying cylinder 3 through the air injection hole 28, so that the raw material in the drying cylinder 3 is blown upward and boiled, and the boiling of the raw material in the drying cylinder 3 can increase the contact area between the raw material and the hot air, so that the raw material is fully dried, and the motor drives the stirring shaft 31 and the stirring blade 32 to rotate, and the inclined surface of the stirring blade 32 can scrape the raw material upward, so that the raw material can move upward under the action of the dry air, and in addition, the liquid raw material is injected into the liquid storage ring 34 through the injection pipe 36, and the liquid raw material is atomized and sprayed into the raw material in the drying cylinder 3 through the atomizing nozzle 35, so that the liquid raw material and the powdered raw material are mixed to form particles, and when the liquid raw material wraps the powdered raw material, the hot air can dry the particles; S5. When the hot air enters the drying cylinder 3 for drying, the hot air carries moisture and is discharged to the outside through the fixed cylinder 37 and the L-shaped exhaust pipe 43, and the dust bag 39 can filter the dust raw materials in the hot air to avoid the dust being discharged to the outside to cause air pollution and waste of raw materials. After the dust bag 39 has filtered the air for a certain period of time, the corresponding electromagnet 54 is energized, and the other electromagnet 54 is de-energized. The magnetic attraction of the electromagnet 54 on the iron block 52 is greater than the pulling force of the second spring 53. At this time, the electromagnet 54 sucks the corresponding iron block 52 out of the sliding groove 51, and then the lifting frame 51 is lifted. After losing the magnetic attraction of the other electromagnet 54, the iron stopper 52 below 48 shrinks to the sliding groove 51 under the action of the second spring 53. When the pulverizing cylinder 2 drives the rotating disk 46 to rotate through the second rotating shaft 10, the rotating disk 46 drives the corresponding connecting rod 50 and the second top plate 42 to reciprocate and rise and fall through the cooperation of the pin shaft 47 and the lifting frame 48, and then drives the dust bag 39 to shake through the cooperation of the second top plate 42, the L-shaped exhaust pipe 43 and the lifting plate 41, so as to shake off the dust attached to the dust bag 39, so that it can enter the drying cylinder 3 again for granulation, thereby avoiding the waste of raw materials.

[0039] However, as is well known to those skilled in the art, the working principles and wiring methods of the first motor 4, the second motor 12, the electromagnet 54 and the electric push rod 20 are commonplace, and are conventional means or common knowledge, and will not be elaborated here. Those skilled in the art may make any optional selections according to their needs or convenience.

[0040] The above description is only a preferred specific implementation manner of the present invention, but the protection scope of the present invention is not limited thereto. Any technician familiar with the technical field can make equivalent replacements or changes according to the technical scheme and inventive concept of the present invention within the technical scope disclosed by the present invention, which should be covered by the protection scope of the present invention.

Claims

1. An integrated particle preparation device combining ball milling and fluidized bed drying, characterized in that: It comprises a frame (1), a pulverizing cylinder (2) is rotatably provided on the top of the frame (1), a plurality of steel balls are provided in the pulverizing cylinder (2), the pulverizing cylinder (2) and the steel balls cooperate to pulverize the raw materials, a drying cylinder (3) is provided on one side of the frame (1), an air inlet cylinder (27) is fixed at the bottom of the drying cylinder (3), and the drying cylinder (3) and the air inlet cylinder (27) are connected via a plurality of air injection holes (28); It also includes two fixed cylinders (37), the bottom ends of the two fixed cylinders (37) are fixed to the top of the drying cylinder (3) and are connected to the drying cylinder (3), and the two fixed cylinders (37) are provided with dust removal bags (39); A crushing structure is arranged on the top of the frame (1) and is used to drive the crushing cylinder (2) to rotate to complete the crushing of the raw materials; A material conveying structure, arranged between the crushing cylinder (2) and the drying cylinder (3), and used for conveying the crushed raw materials in the crushing cylinder (2) to the drying cylinder (3); A drying and granulating structure, arranged in the drying cylinder (3) and the air inlet cylinder (27), for drying and granulating the raw materials; The shaking structure is arranged between the fixed cylinder (37) and the drying cylinder (3) and is used to alternately shake the two dust removal bags (39), and the crushing structure can provide driving force for the shaking structure.

2. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 1, characterized in that: The pulverizing structure comprises a support seat (8) fixed on the top of the frame (1); a first rotating shaft (9) and a second rotating shaft (10) are respectively fixed at both ends of the pulverizing cylinder (2); one end of the first rotating shaft (9) rotates and penetrates the support seat (8) to make the rotation of the pulverizing cylinder (2) more stable; a gear ring (11) is fixed at one end of the pulverizing cylinder (2) close to the first rotating shaft (9); a second motor (12) is fixed at the top of the frame (1); an output shaft of the second motor (12) rotates and penetrates the support seat (8) and is fixed with a first gear (13), and the first gear (13) is meshed with the gear ring (11); a feed pipe (5) is fixedly connected to one side of the top of the pulverizing cylinder (2); a discharge pipe (6) is fixedly connected to one side of the bottom of the pulverizing cylinder (2); a sieve plate (7) is fixed in the discharge pipe (6) to screen the pulverized raw materials.

3. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 2, characterized in that: The feeding structure comprises a feed hopper (14) fixed on one side of the drying cylinder (3), and the feed hopper (14) is connected to the drying cylinder (3), the feed hopper (14) is located below the discharge pipe (6), two bases (22) are fixed on both sides of the discharge pipe (6), and a same rotating rod (23) is rotatably penetrated in the two bases (22) located on the same side, and two rotating plates (24) for closing the discharge pipe (6) are provided at the bottom of the discharge pipe (6), and the two rotating plates (24) are respectively connected to the two The two rotating rods (23) are fixedly connected, and the outer walls of the two rotating rods (23) are each sleeved with two torsion springs (25). The ends of the two torsion springs (25) close to each other are respectively fixedly connected to the corresponding bases (22), and the other ends of the two torsion springs (25) are each fixedly connected to the rotating plate (24). The outer walls of the two rotating rods (23) are each fixedly sleeved with a second gear (26). A return plate (17) matching with the discharge pipe (6) is slidably connected in the feed hopper (14). The return plate (17) is A rack (21) is fixed to the inner walls on both sides away from each other, and the rack (21) is meshed with a second gear (26) for driving the rotating plate (24) to rotate and release the seal of the discharge pipe (6). A first chute (15) and a second chute (16) are respectively provided on the side where the feed hopper (14) and the drying cylinder (3) are close to each other. The first chute (15) and the second chute (16) are slidably connected with the same Z-shaped rod (19). One end of the Z-shaped rod (19) extends into the feed hopper (14) and is connected to the return chute (16). The plate (17) is fixedly connected, one end of the Z-shaped rod (19) extends into the drying cylinder (3) and is fixedly connected to the closing plate (18), and the closing plate (18) is used to close the feed hopper (14), and an electric push rod (20) is fixed to one side of the drying cylinder (3), and the output shaft of the electric push rod (20) is fixedly connected to the Z-shaped rod (19) and is used to synchronously drive the return plate (17) and the closing plate (18) to move upward, and the return plate (17) moves upward and cooperates with the discharge pipe (6) to prevent the raw materials from contacting external bacteria during discharge.

4. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 3, characterized in that: The drying granulation structure comprises a stirring shaft (31) rotating on the inner wall of the bottom of a drying cylinder (3); a partition (30) is fixed in the drying cylinder (3); a plurality of fine holes are provided in the partition (30) for allowing the hot air in the air inlet cylinder (27) to flow upward, and the top end of the stirring shaft (31) rotates to penetrate the partition (30); a plurality of stirring blades (32) are fixed on the outer wall of the stirring shaft (31); one side of each of the plurality of stirring blades (32) is provided with an inclined surface for causing the raw material to move upward along the inclined surface when stirring the raw material; a liquid storage ring (34) is fixed in the drying cylinder (3); a plurality of atomizing nozzles (35) are fixed in the liquid storage ring (34); an injection pipe (36) connected to the liquid storage ring (34) is fixed and penetrated on one side of the drying cylinder (3); an end of the injection pipe (36) away from the liquid storage ring (34) is connected to an external liquid raw material bin for injecting liquid raw material into the drying cylinder (3).

5. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 4, characterized in that: The shaking structure comprises two fixing rings (38), the two fixing rings (38) are respectively fixed in two fixing cylinders (37), the bottom ends of the two dust removal bags (39) are respectively fixedly connected to the tops of the two fixing rings (38), the tops of the two dust removal bags (39) are both fixedly connected with a first top plate (40), the two fixing cylinders (37) are both sealed and slidably connected with a lifting plate (41), the bottoms of the two lifting plates (41) are respectively fixedly connected to the tops of the two first top plates (40) for driving the dust removal bags (39) to shake, the tops of the two fixing cylinders (37) are each provided with a second top plate (42), the two second top plates (42) ) are slidably penetrated by a plurality of fixing rods (44), and the plurality of fixing rods (44) located in the same second top plate (42) are fixed to the top of the corresponding fixing tube (37), a plurality of first springs (45) are fixed between the bottom of the second top plate (42) and the top of the fixing tube (37), and the first springs (45) are sleeved on the outer wall of the fixing rods (44), and an L-shaped exhaust pipe (43) is fixedly penetrated by the two second top plates (42), and the bottom ends of the two L-shaped exhaust pipes (43) are respectively fixedly penetrated by the corresponding lifting plates (41), and the lifting plates (41) are driven to reciprocate up and down by the cooperation between the second top plate (42) and the L-shaped exhaust pipe (43).

6. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 5, characterized in that: The shaking structure also includes a rotating disk (46) located between the two fixed cylinders (37), the rotating disk (46) being fixedly connected to one end of the second rotating shaft (10) away from the crushing cylinder (2), a sliding rod (49) slidingly penetrates the top of the drying cylinder (3), a lifting frame (48) is fixed to the top of the sliding rod (49), a pin shaft (47) is slidably fitted in the lifting frame (48), one end of the pin shaft (47) is fixed to a side of the rotating disk (46) that deviates from the center of the circle, electromagnets (54) are fixed to both sides of the bottom of the lifting frame (48), connecting rods (50) are fixed to the sides of the two second top plates (42) that are close to each other, and the two The sides of the connecting rods (50) that are close to each other are respectively slidably matched with the two ends of the lifting frame (48). The sides of the two connecting rods (50) that are close to each other are each provided with a sliding groove (51). The two sliding grooves (51) are both slidably connected with iron blocks (52), and magnetic attraction is generated between the iron blocks (52) and the electromagnet (54). The iron blocks (52) cooperate with the lifting frame (48) to enable the lifting frame (48) to drive the connecting rods (50) and the second top plate (42) to move downward. The sides of the two iron blocks (52) that are away from each other are each fixed with a second spring (53), and the two second springs (53) are respectively fixed in the corresponding sliding grooves (51).

7. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 6, characterized in that: The bottom of the air intake cylinder (27) is fixedly connected to an air intake pipe (29), and the air intake pipe (29) is connected to an external drying hot air source through a hose. A discharge pipe (33) is fixedly connected to one side of the drying cylinder (3), and the top end of the discharge pipe (33) is fixedly passed through the partition (30). The outer walls of the discharge pipe (33) and the air intake pipe (29) are both provided with solenoid valves.

8. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 7, characterized in that: The magnetic attraction force between the iron stopper (52) and the electromagnet (54) is greater than the pulling force of the second spring (53).

9. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 8, characterized in that: The torsion force of the torsion spring (25) is greater than the weight of the rotating plate (24), and is used to reset the rotating plate (24) and rotate to close the discharge pipe (6) when the rack (21) is disengaged from the second gear (26).

10. The integrated particle preparation device combining ball milling and fluidized bed drying according to claim 9, characterized in that: The inner walls of the two sides of the crushing cylinder (2) that are away from each other are both rotatably connected to the third rotating shaft (55), and the outer walls of the two third rotating shafts (55) are both fixed with a plurality of connecting frames (56), and one end of the two corresponding connecting frames (56) located on the two third rotating shafts (55) is fixed with a same scraper (57) for stirring the steel balls and raw materials in the crushing cylinder (2), and one end of the third rotating shaft (55) close to the support seat (8) is rotatably passed through the first rotating shaft (9), and a first motor (4) is fixed to one side of the support seat (8) through a frame, and an output shaft of the first motor (4) is fixedly connected to one end of the third rotating shaft (55).

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