Biological sample automatic detection equipment and detection method

Abstract

The invention discloses biological sample automatic detection equipment and a detection method, and relates to the technical field of biological detection. The biological sample automatic detection equipment comprises a rack, a control module, and a consumable supply module, a sample supply module, a detection module and a consumable transfer module which are arranged on the rack, the consumable supply module is used for placing consumable bodies and transferring the consumable bodies to the processing station; the sample supply module is used for placing a sample tube and adding a sample in the sample tube into the consumable body of the processing station; the detection module is used for detecting the consumable body added with the sample; the consumable transfer module is used for transferring the consumable body added with the sample to the detection module, and the control module is used for coordinating work. The biological sample automatic detection equipment disclosed by the invention avoids the risk of pollution in the sample adding process, adopts automatic operation to reduce the labor intensity of workers, and improves the detection efficiency.

Description

Technical Field

[0001] The present application relates to the field of biological detection technology, and in particular, to an automatic detection device and a detection method for biological samples. Background Art

[0002] In vitro diagnosis is an important part of modern testing medicine. The clinical application of in vitro diagnosis runs through the entire process of disease prevention, preliminary diagnosis, selection of treatment plans and evaluation of efficacy. Molecular diagnosis (such as nucleic acid testing) is the technical basis of precision medicine and precision testing, and is also the fastest growing sub-industry in in vitro diagnosis. Among them, for example, the use of nucleic acid testing equipment to extract and detect nucleic acids from samples is an important task of molecular diagnosis.

[0003] Nucleic acid testing equipment generally uses PCR (Polymerase Chain Reaction) technology. When using PCR technology for nucleic acid testing, samples need to be extracted, transferred, mixed, and other pre-test treatments. Current nucleic acid testing equipment usually performs nucleic acid amplification and testing on a single consumable that is pre-installed with a sample. However, the operation of placing the sample in each corresponding consumable is usually manually added by the operator. Since the consumables are open structures and multiple consumables are placed closely together during the adding process, there is a greater risk of contamination in the process of manually adding samples. After adding the sample, the consumable is transferred to the nucleic acid testing equipment for testing, which greatly reduces work efficiency and increases labor intensity. Summary of the invention

[0004] The purpose of this application is to provide a biological sample automatic detection device and detection method to solve the deficiencies in the prior art.

[0005] To achieve the above objectives, in a first aspect, the present application provides a biological sample automatic detection device, comprising:

[0006] A frame, wherein a first feeding station, a second feeding station, a processing station and a detection station are provided on the frame, wherein the first feeding station, the processing station and the second feeding station are arranged in a first horizontal direction (X), and the detection station is arranged in a second horizontal direction (Y);

[0007] A consumables supply module, arranged at the first feeding station, for placing the consumables body and supplying the consumables body to the processing station, wherein the processing station is provided with a first positioning portion for positioning the consumables body;

[0008] A sample supply module, disposed at the second feeding station, for placing a sample tube and for adding the sample in the sample tube to the consumable body of the processing station;

[0009] A detection module, disposed at the detection station, for detecting the consumable body with the sample added thereto;

[0010] a consumable transfer module, disposed on the frame and between the detection station and the processing station, for transferring the consumable body with the sample added thereto to the detection module; and

[0011] The control module is used to control the collaborative work among the sample supply module, the consumable supply module, the detection module and the consumable transfer module.

[0012] As a further improvement of the above technical solution:

[0013] In combination with the first aspect, in a possible implementation manner, the consumable supply module includes:

[0014] A consumables carrier module, disposed on the frame and located at the first feeding station, for placing the consumables body to be used; and

[0015] The first robot is arranged on the frame and is used for grabbing the consumable body and transferring it to the processing station.

[0016] In combination with the first aspect, in a possible implementation manner, the consumable carrier module includes:

[0017] A first push-pull assembly is disposed on the frame; and

[0018] A consumable material positioning jig is arranged on the first push-pull assembly, and a second positioning portion for positioning the consumable material body is provided on the consumable material positioning jig, wherein the first push-pull assembly can drive the consumable material positioning jig to enter and exit the first feeding station.

[0019] In combination with the first aspect, in a possible implementation manner, the sample supply module includes:

[0020] A sample carrier module, disposed on the rack and used for placing a sample tube containing a sample;

[0021] A sample clamping module, disposed on the rack, for clamping the transferred sample tube;

[0022] A gun tip carrier module, disposed on the frame and used for placing a liquid extraction gun tip; and

[0023] The second manipulator is arranged on the frame, and the second manipulator can move between the second feeding station and the processing station. The second manipulator includes a first gripper module and a second gripper module, wherein the first gripper module is used to grab the sample tube to transfer and screw the tube cap of the sample tube, and the second gripper module is used to absorb the sample in the sample tube by using the corresponding liquid collection gun head and add it to the consumable body.

[0024] In combination with the first aspect, in a possible implementation, the sample carrier module includes:

[0025] A sample base, disposed on the frame, wherein at least one slide groove is disposed on the surface of the sample base, and a baffle is disposed at one end of the sample base; and

[0026] At least one sample carrier bar, each of which is used to carry at least one sample tube, and the sample carrier bar is slidably matched with the corresponding slide groove;

[0027] Wherein, the baffle plate is provided with a detector electrically connected to the control module corresponding to each of the slide grooves, and the sample carrier bar is provided with a trigger component. When the sample carrier bar slides along the corresponding slide groove and abuts against the baffle plate, the trigger component triggers the detector, and the detector sends out an in-position signal.

[0028] In combination with the first aspect, in a possible embodiment, the sample carrier module also includes a magnetic attraction component, and a first magnetic attraction component is provided at one end of the sample carrier bar facing the baffle, and the magnetic attraction component is arranged on the baffle corresponding to each of the slide grooves, and the magnetic attraction component is used to attract each other with the first magnetic attraction component.

[0029] In combination with the first aspect, in a possible implementation, the magnetic attraction component includes a second magnetic attraction component and / or an electromagnetic attraction component, wherein at least one of the second magnetic attraction component and the first magnetic attraction component is a permanent magnet component.

[0030] In combination with the first aspect, in a possible implementation, the sample carrier module, the sample clamping module and the gun tip carrier module are distributed in sequence along the first horizontal direction (X).

[0031] In combination with the first aspect, in a possible embodiment, the sample supply module also includes a sample recovery rack module, which is arranged in the rack and between the sample carrier module and the sample clamping module, and the sample recovery rack module is used to collect the sample tube after the sample absorption is completed.

[0032] In combination with the first aspect, in a possible implementation manner, the gun tip carrier module includes:

[0033] A second push-pull assembly is disposed on the frame; and

[0034] The gun tip positioning frame is arranged on the second push-pull assembly, and the gun tip positioning frame is provided with a third positioning portion for positioning the liquid taking gun tip, wherein the second push-pull assembly can drive the gun tip positioning frame to enter and exit the second feeding station.

[0035] In combination with the first aspect, in a possible implementation, the consumable transfer module includes a first drive module, a second drive module, a third drive module, a movable arm and a third clamping claw module, the first drive module is arranged on the frame, the second drive module is arranged on the first drive module, the third drive module is arranged on the second drive module, one end of the movable arm frame is connected to the third drive module, and the other end is provided with the third clamping claw module;

[0036] Among them, the first driving module can drive the second driving module to move along the first horizontal direction, the second driving module can drive the third driving module to move along the vertical direction, and the third driving module can drive the movable arm and drive the third clamping module to rotate around the axis located in the vertical direction. Under the cooperation of the first driving module, the second driving module and the third driving module, the third clamping module can grab the consumable body for transfer.

[0037] In combination with the first aspect, in a possible implementation, the biological sample automatic detection equipment also includes an ultrasonic vibration module, which is arranged at the processing station and electrically connected to the control module, and the ultrasonic vibration module can selectively perform ultrasonic vibration on the consumable body with the sample added.

[0038] In combination with the first aspect, in a possible implementation, the ultrasonic vibration module includes an ultrasonic processing module and an avoidance driving module, the avoidance driving module is arranged on the frame, and the ultrasonic processing module is arranged on the avoidance driving module;

[0039] When the consumable transfer module transfers the consumable body, the avoidance driving module drives the ultrasonic processing module to move out of the processing station along the second horizontal direction.

[0040] To achieve the above-mentioned purpose, in a second aspect, the present application further provides a biological sample automatic detection method, which applies the biological sample automatic detection device provided in the above-mentioned first aspect, and the biological sample automatic detection method comprises:

[0041] Placing the sample tube containing the sample in the sample supply module, and pre-placing the consumable body to be used on the consumable supply module;

[0042] Transferring at least one of the consumable bodies to the processing station for standby use through the consumable supply module;

[0043] Adding the sample in the sample tube into the corresponding consumable body through the sample supply module;

[0044] The consumable body with the sample added thereto is transferred to the detection module for detection by the consumable transfer module, and the consumable body after detection is transferred to a designated area for disposal by the consumable transfer module.

[0045] Compared with the prior art, the present invention has the following beneficial effects:

[0046] The present application provides an automatic biological sample detection device and detection method, wherein the biological sample automatic detection device, when performing detection, first places the sample tube containing the sample in the sample supply module, and pre-places the consumable body to be used on the consumable supply module, and then starts the detection. During the detection process, at least one consumable body is transferred to the processing station for standby through the consumable supply module; the sample in the sample tube is added to the corresponding consumable body through the sample supply module; the consumable body with the added sample is transferred to the detection module through the consumable transfer module for detection, and the consumable body that has completed the detection can also be transferred to the designated area for disposal through the consumable transfer module. Therefore, the biological sample automatic detection device provided by the present application does not require manual participation in the subsequent detection process, and the supply of samples, the supply of consumable bodies and the addition of samples are all automatically performed at different stations, which greatly avoids the risk of contamination during the sample addition process, and the use of automated operations reduces manual labor intensity and improves detection efficiency.

[0047] Other features and advantages of the present application will be described in detail in the subsequent detailed description. BRIEF DESCRIPTION OF THE DRAWINGS

[0048] The accompanying drawings are used to provide a further understanding of the present application and constitute a part of the specification. Together with the following specific embodiments, they are used to explain the present application. It should be understood that the following drawings only show certain embodiments of the present application and should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work. In the drawings:

[0049] Figure 1 A front view of an automatic biological sample detection device provided in an embodiment of the present application is shown;

[0050] Figure 2 Shows Figure 1 A schematic diagram of a partial structure of a rack in the biological sample automatic detection device shown;

[0051] Figure 3 Shows Figure 1 A schematic diagram of the three-dimensional structure of the biological sample automatic detection device shown;

[0052] Figure 4 Shows Figure 3 A schematic diagram of the three-dimensional structure of a consumable transfer module in the biological sample automatic detection device shown;

[0053] Figure 5 Shows Figure 3 A partially exploded schematic diagram showing a first manipulator of a consumable supply module and a second manipulator of a sample supply module in an automatic biological sample detection device installed on a stand;

[0054] Figure 6 An exploded schematic diagram of a consumable carrier module in a consumable supply module provided in an embodiment of the present application is shown;

[0055] Figure 7 An exploded schematic diagram of a sample carrier module in a sample supply module provided in an embodiment of the present application is shown;

[0056] Figure 8 A schematic diagram of an exploded view of a sample clamping module in a sample supply module provided in an embodiment of the present application is shown;

[0057] Fig. 9 A schematic diagram of the three-dimensional structure of a gun tip carrier module in a sample supply module provided in an embodiment of the present application is shown;

[0058] Fig.10 A partial structural schematic diagram of an ultrasonic vibration module in an automatic biological sample detection device provided in an embodiment of the present application is shown.

[0059] Description of reference numerals:

[0060] 10. Consumables body; 20. Sample tube; 30. Liquid collection gun tip;

[0061] 100, rack; 101, first feeding station; 102, second feeding station; 103, processing station; 104, testing station; 105, ground space; 110, work surface; 120, avoidance space; 130, material rack; 140, stand;

[0062] 200, consumable material transfer module; 210, first drive module; 220, second drive module; 230, third drive module; 240, movable arm; 250, third clamping claw module;

[0063] 300, consumables supply module; 310, consumables carrier module; 311, first push-pull assembly; 3110, push-pull base; 3111, push-pull movable seat; 3112, first slide rail slider mechanism; 3113, push-pull handle; 312, consumables positioning fixture; 3120, second positioning part; 320, first manipulator; 321, fourth drive module; 322, fifth drive module; 323, sixth drive module; 324, fourth clamping claw module; 325, first dust cover;

[0064] 400, sample supply module; 410, sample carrier module; 411, sample base; 4110, slide; 4111, baffle; 412, sample carrier bar; 413, detector; 414, magnetic suction component; 4140, second magnetic suction component; 4141, electromagnetic suction component; 415, first magnetic suction component; 416, sensor; 420, sample clamping module; 421, sample clamping seat; 4210, clamping positioning hole; 422, sample clamping component; 422 0, clamping head; 4221, clamping chamber; 430, gun head carrier module; 431, second push-pull assembly; 432, gun head positioning frame; 440, second manipulator; 441, seventh drive module; 442, eighth drive module; 443, ninth drive module; 444, second clamping claw module; 445, first clamping claw module; 446, second dust cover; 447, ranging sensor; 448, barcode scanner; 450, sample recovery rack module; 451, recovery rack;

[0065] 500, detection module; 510, extraction and amplification module;

[0066] 600, ultrasonic vibration module; 610, ultrasonic processing module; 6101, accommodating space; 611, ultrasonic mounting seat; 612, ultrasonic device; 613, lifting mechanism; 614, consumables clamping mechanism; 6140, clamping drive assembly; 6141, clamping arm; 615, positioning guide seat; 6150, positioning groove; 620, avoidance drive module; 621, base; 622, avoidance drive mechanism; 623, slide seat; 624, third slide rail slider mechanism. DETAILED DESCRIPTION

[0067] The specific implementation of the embodiment of the present application is described in detail below in conjunction with the accompanying drawings. It should be understood that the specific implementation described here is only used to illustrate and explain the embodiment of the present application, and is not used to limit the embodiment of the present application.

[0068] It should be noted that, in the absence of conflict, the embodiments and features in the embodiments of the present application may be combined with each other.

[0069] In the embodiments of the present application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "radial", "circumferential" and the like indicate orientations or positional relationships based on the orientations or positional relationships shown in the accompanying drawings, and are only for the convenience of describing the present application and simplifying the description, and do not indicate or imply that the referred device or element must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be understood as a limitation on the present application.

[0070] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of the features. In the description of this application, the meaning of "plurality" is two or more, unless otherwise clearly and specifically defined.

[0071] In this application, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0072] The present application will be described in detail below with reference to the accompanying drawings and in conjunction with exemplary embodiments.

[0073] Example

[0074] See also Figure 1 , Figure 2 and Figure 3 , this embodiment provides a biological sample automatic detection device, specifically relates to a nucleic acid automatic detection device.

[0075] In this embodiment, the biological sample automatic detection device includes a frame 100, a consumable supply module 300, a sample supply module 400, a detection module 500, a consumable transfer module 200 and a control module (not shown). The consumable supply module 300, the sample supply module 400, the detection module 500, and the consumable transfer module 200 are all arranged on the frame 100 and electrically connected to the control module. The control module can respectively control the consumable supply module 300, the sample supply module 400, the detection module 500, and the consumable transfer module 200 to work together, thereby completing the fully automated detection of the sample by coordinating the actions of the consumable supply module 300, the sample supply module 400, the detection module 500, and the consumable transfer module 200.

[0076] In this embodiment, the rack 100 has a work surface 110, and there is a certain ground space 105 below the work surface 110, which can be used to arrange the electrical components in the control module or to place the waste recycling bin. Further, the length direction of the work surface 110 is defined as the first horizontal direction X, the width direction of the work surface 110 is defined as the second horizontal direction Y, and the vertical direction Z is parallel to the normal of the work surface 110. Therefore, the first horizontal direction X, the second horizontal direction Y and the vertical direction Z are perpendicular to each other.

[0077] Furthermore, a clearance space 120 is provided in the middle of the work surface 110, and the clearance space 120 extends along the first horizontal direction X and divides the work surface 110 into two areas. One area is provided with a first feeding station 101, a second feeding station 102 and a processing station 103, and the other area is provided with a detection station 104. The first feeding station 101, the processing station 103 and the second feeding station 102 are arranged in the first horizontal direction X, and the detection station 104 is arranged in the second horizontal direction Y.

[0078] The consumable material supply module 300 is disposed on the frame 100 and arranged at the first feeding station 101. The consumable material supply module 300 is used to place the consumable material body 10 and transfer the consumable material body 10 to the processing station 103 (see Fig.10 ), the processing station 103 is provided with a first positioning portion for positioning the consumable body 10. The consumable body 10 is usually disposable and must be discarded to a designated area for centralized processing after the inspection is completed.

[0079] The sample supply module 400 is disposed on the rack 100 and arranged at the second feeding station 102. The sample supply module 400 is used to place the sample tube 20 (see Figure 7 ) and is used to add the sample in the sample tube 20 to the consumable body 10 of the processing station 103.

[0080] The detection module 500 is disposed at the detection station 104 , and the detection module 500 is used to detect the consumable body 10 with the sample added thereto.

[0081] The consumable transfer module 200 is disposed on the frame 100 and between the detection station 104 and the processing station 103. The consumable transfer module 200 is used to transfer the consumable body 10 with the sample added to the detection module 500. The avoidance space 120 can provide a moving space for the consumable transfer module 200 to prevent the consumable transfer module 200 from interfering with other modules or the frame 100 during the process of transferring the consumable body 10.

[0082] The control module can coordinate the work among the sample supply module 400, the consumable supply module 300, the detection module 500 and the consumable transfer module 200 through an internal program to realize the automatic work of the sample supply module 400, the consumable supply module 300, the detection module 500 and the consumable transfer module 200. The control module can be selected as a PLC controller or an industrial computer.

[0083] In order to more clearly describe the technical solution of this embodiment, the detailed structure of each of the above modules is described below, as follows:

[0084] See also Figure 1 and Figure 3 The above-mentioned detection module 500 includes a plurality of extraction and amplification modules 510 arranged on the rack 100, and the plurality of extraction and amplification modules 510 are distributed along the first horizontal direction X, or the plurality of extraction and amplification modules 510 are arranged in multiple layers on the rack 100 along the vertical direction Z, and a preset number of extraction and amplification modules 510 are arranged in each layer along the first horizontal direction X.

[0085] In this embodiment, if Figure 3 As shown, a two-layer material rack 130 is arranged on the work surface 110 of the rack 100, and each layer of the material rack 130 is provided with eight extraction and amplification modules 510. Therefore, in this embodiment, sixteen consumable bodies 10 can be tested simultaneously. It should be understood that the above is only an example and is not intended to limit the scope of protection of the present application. In some embodiments, a three-layer, four-layer or other layer structure material rack 130 can be arranged, and each layer can be provided with one, two, three, four, ten or other number of extraction and amplification modules 510.

[0086] Please also read Figure 4The consumable transfer module 200 includes a first driving module 210, a second driving module 220, a third driving module 230, a movable arm 240 and a third clamping module 250. The first driving module 210 is arranged on the frame 100, the second driving module 220 is arranged on the first driving module 210, the third driving module 230 is arranged on the second driving module 220, one end of the movable arm 240 is connected to the third driving module 230, and the other end is provided with the third clamping module 250.

[0087] Among them, the first driving module 210 can drive the second driving module 220 to move along the first horizontal direction X, the second driving module 220 can drive the third driving module 230 to move along the vertical direction Z, and the third driving module 230 can drive the movable arm 240 and drive the third clamping module 250 to rotate around the axis located in the vertical direction Z. Optionally, the third clamping module 250 is a pneumatic clamp. Therefore, under the action coordination of the first driving module 210, the second driving module 220 and the third driving module 230, the third clamping module 250 can grab the consumable body 10 for transfer. And in this embodiment, the stroke of the second driving module 220 driving the third driving module 230 to move along the vertical direction Z is adapted to the number of layers of the rack 130. In this embodiment, the third driving module 230 is arranged to drive the movable arm 240 and drive the third clamping module 250 to rotate around the axis located in the vertical direction Z so that the third clamping module 250 can flexibly transfer the consumable body 10 between the processing station 103 and the detection station 104 on both sides of the avoidance space 120.

[0088] Optionally, the first drive module 210 and the third drive module 230 can use a cylinder, an oil cylinder, an electric cylinder, an electric push rod, a linear motor or a motor screw as a power source. Optionally, the second drive module 220 can use a motor, a rotary oil cylinder or a rotary cylinder as a power source. It should be understood that the above is only an example and is not intended to limit the scope of protection of this application.

[0089] See also Figure 1 , Figure 3 , Figure 5 and Figure 6 The consumable supply module 300 includes a consumable carrier module 310 and a first manipulator 320. The consumable carrier module 310 is disposed on the frame 100 and located at the first feeding station 101. The consumable carrier module 310 is used to place a plurality of consumable bodies 10 to be used. The first manipulator 320 is disposed on the frame 100. The first manipulator 320 is used to grab the consumable body 10 and transfer it to the processing station 103. The first positioning portion located at the processing station 103 can position the transferred consumable body 10.

[0090] In this embodiment, the first manipulator 320 is arranged on the stand 140 of the frame 100, and the first manipulator 320 is located above the first feeding station 101 as a whole. The first manipulator 320 includes a fourth drive module 321, a fifth drive module 322, a sixth drive module 323 and a fourth gripper module 324. The fourth drive module 321 is arranged on the stand 140, the fifth drive module 322 is arranged on the fourth drive module 321, the sixth drive module 323 is arranged on the fifth drive module 322, and the fourth gripper module 324 is arranged on the sixth drive module 323.

[0091] Among them, the fourth driving module 321 can drive the fifth driving module 322 to move along the first horizontal direction X, the fifth driving module 322 can drive the sixth driving module 323 to move along the second horizontal direction Y, and the sixth driving module 323 can drive the fourth clamping module 324 to move along the vertical direction Z. Optionally, the fourth clamping module 324 is a pneumatic clamping module. Therefore, under the cooperation of the fourth driving module 321, the fifth driving module 322, and the sixth driving module 323, the first manipulator 320 has the freedom to move along the first horizontal direction X, the second horizontal direction Y, and the vertical direction Z, thereby ensuring that the fourth clamping module 324 in the first manipulator 320 can smoothly grasp the consumable body 10 for transfer and accurately place the consumable body 10 on the first positioning portion.

[0092] Optionally, the fourth drive module 321, the fifth drive module 322, and the sixth drive module 323 can all use a cylinder, an oil cylinder, an electric cylinder, an electric push rod, a linear motor, or a motor screw as a power source. It should be understood that the above is only an example and is not intended to limit the scope of protection of this application.

[0093] In some embodiments, the fourth driving module 321 is slidably disposed on the stand 140 , and the fourth driving module 321 drives the fifth driving module 322 to move along the first horizontal direction X using a motor and a synchronous belt transmission mechanism.

[0094] See also Figure 1 , Figure 3 and Figure 6 Further, in this embodiment, a plurality of consumable carrier modules 310 may be provided, and the plurality of consumable carrier modules 310 are sequentially distributed along the first horizontal direction X, and a plurality of consumable bodies 10 may be placed on each consumable carrier module 310, thereby reducing the frequency of loading and improving the operation efficiency. In order to more clearly describe the technical solution of the present application, one of the plurality of consumable carrier modules 310 is described below.

[0095] Specifically, the consumable carrier module 310 includes a first push-pull assembly 311 and a consumable positioning fixture 312. The first push-pull assembly 311 is disposed on the frame 100; the consumable positioning fixture 312 is disposed on the first push-pull assembly 311, and the consumable positioning fixture 312 is provided with a plurality of second positioning parts 3120 for positioning the consumable body 10, wherein the first push-pull assembly 311 can drive the consumable positioning fixture 312 to enter and exit the first feeding station 101.

[0096] The first push-pull assembly 311 includes a push-pull base 3110, a push-pull movable base 3111 and a first slide rail slider mechanism 3112. The push-pull base 3110 is connected to the rack 100, for example, fixedly connected or detachably connected, wherein the fixed connection method can be selected as a welding connection, and the detachable connection method can be selected as a screw connection or a clamping connection. The push-pull movable base 3111 is slidably arranged on the push-pull base 3110 through the first slide rail slider mechanism 3112, and a push-pull handle 3113 is provided at one end of the push-pull movable base 3111 along the second horizontal direction Y.

[0097] The consumables positioning fixture 312 is detachably arranged on the push-pull movable seat 3111, and the detachable manner includes snap connection or screw connection to facilitate the replacement of different types of consumables positioning fixtures 312. Of course, in some embodiments, the consumables positioning fixture 312 can also be fixedly arranged on the push-pull movable seat 3111.

[0098] See also Figure 3 , Figure 7 , Figure 8 and Fig. 9 The sample supply module 400 includes a sample carrier module 410, a sample clamping module 420, a gun tip carrier module 430, and a second manipulator 440. The sample carrier module 410, the sample clamping module 420, and the gun tip carrier module 430 are all arranged on the rack 100 and located at the second feeding station 102, wherein the sample carrier module 410, the sample clamping module 420, and the gun tip carrier module 430 are sequentially distributed along the first horizontal direction X. The sample carrier module 410 is used to place a plurality of sample tubes 20 containing samples; the sample clamping module 420 is used to clamp the transferred sample tubes 20; the gun tip carrier module 430 is used to place the liquid extraction gun tip 30 (see Fig. 9 ), when in use, each liquid collection gun head 30 supplies a sample tube 20 to prevent cross contamination.

[0099] Please also read Figure 5, the second manipulator 440 is arranged on the above-mentioned stand 140, that is, the first manipulator 320 and the second manipulator 440 are arranged on the common stand 140. Therefore, the second manipulator 440 is located above the second feeding station 102, so that the second manipulator 440 is convenient to move between the second feeding station 102 and the processing station 103. By reasonably arranging the first manipulator 320 and the second manipulator 440, the space in the vertical direction Z is reasonably utilized, the compactness of the equipment structure is improved, and the installation space is saved.

[0100] The second manipulator 440 includes a seventh driving module 441, an eighth driving module 442 and a ninth driving module 443, wherein the structures and design schemes of the seventh driving module 441, the eighth driving module 442 and the ninth driving module 443 can refer to the fourth driving module 321, the fifth driving module 322 and the sixth driving module 323 in the first manipulator 320 mentioned above, and will not be described in detail here.

[0101] Further, the second manipulator 440 also includes a first gripper module 445 and a second gripper module 444 disposed on the ninth driving module 443, wherein the first gripper module 445 can grab the sample tube 20 to transfer and screw the tube cover of the sample tube 20 under the cooperation of the seventh driving module 441, the eighth driving module 442 and the ninth driving module 443, and the second gripper module 444 can absorb the sample in the sample tube 20 by taking the corresponding liquid collection gun head 30 to add it to the consumable body 10 under the cooperation of the seventh driving module 441, the eighth driving module 442 and the ninth driving module 443. Among them, the first gripper module 445 includes a screwing assembly and a pneumatic gripper disposed at the output end of the screwing assembly, and the screwing assembly can drive the pneumatic gripper to rotate to screw the tube cover of the sample tube 20. Optionally, the screwing assembly is a motor, and the second gripper module 444 can be selected as a liquid collection gun.

[0102] Furthermore, a distance measuring sensor 447 and a barcode scanner 448 are also provided on the ninth driving module 443 of the second manipulator 440, wherein the distance measuring sensor 447 is used to identify sample tubes 20 at different heights on the sample carrier module 410; and the barcode scanner 448 is used to scan the information barcode on the sample tube 20.

[0103] Further, such as Figure 5 As shown, in this embodiment, a first dust cover 325 is provided on the first manipulator 320 , and a second dust cover 446 is provided on the second manipulator 440 .

[0104] See also Figure 7The sample carrier module 410 includes a sample base 411 and at least one sample carrier bar 412. In this embodiment, four sample carrier bars 412 are provided. The sample base 411 is provided on the rack 100. Four slide grooves 4110 are provided on the surface of the sample base 411. Each slide groove 4110 corresponds to a sample carrier bar 412. A baffle 4111 is provided at one end of the sample base 411. Each sample carrier bar 412 is used to carry at least one sample tube 20. The sample carrier bar 412 is slidably matched with the corresponding slide groove 4110.

[0105] The baffle plate 4111 is provided with a sensor 416 electrically connected to the control module corresponding to each slide groove 4110, and a trigger (not shown) is provided on the end surface of the sample carrier bar 412 close to the baffle plate 4111. When the sample carrier bar 412 slides along the corresponding slide groove 4110 and abuts against the baffle plate 4111, the trigger triggers the detector 413, and the detector 413 is used to send an arrival signal. Optionally, the detector 413 is a photoelectric sensor, an infrared sensor or a Hall sensor.

[0106] Furthermore, the sample carrier module 410 further includes a magnetic attraction component 414, and a first magnetic attraction component 415 is provided at one end of the sample carrier strip 412 facing the baffle plate 4111, and a magnetic attraction component 414 is arranged on the baffle plate 4111 corresponding to each slide slot 4110, and the magnetic attraction component 414 is used to attract the first magnetic attraction component 415. Thus, the sample carrier strip 412 is stably placed on the sample base 411 through the magnetic attraction, so that a certain resistance can be provided when the sample carrier strip 412 is taken out to prevent the sample carrier strip 412 from being accidentally touched.

[0107] In this embodiment, the magnetic attraction assembly 414 includes a second magnetic attraction member 4140 and an electromagnetic attraction member 4141, wherein at least one of the second magnetic attraction member 4140 and the first magnetic attraction member 415 is a permanent magnet. Through the magnetic force cooperation between the first magnetic attraction member 415 and the second magnetic attraction member 4140, a certain adsorption force is provided when installing the sample carrier bar 412, so that the end of the sample carrier bar 412 is quickly attached to the baffle 4111, thereby generating a collision effect, which can be transmitted to the operator through the reaction force, so that the operator can judge whether the sample carrier bar 412 is installed in place. At the same time, the magnetic force cooperation between the first magnetic attraction member 415 and the second magnetic attraction member 4140 can also prevent the installed sample carrier bar 412 from sliding freely in the slide groove 4110, and can also provide resistance for removing the sample carrier bar 412 to prevent accidental collision. The electromagnetic adsorption member 4141 is electrically connected to the control module. When the control module obtains the in-position signal sent by the detector 413, it controls the electromagnetic adsorption member 4141 to be powered according to the in-position signal, so that the electromagnetic adsorption member 4141 generates a greater magnetic force to adsorb the sample carrier bar 412, further improving the stability of the sample carrier bar 412 after installation to prevent accidental contact. Of course, in some embodiments, only one of the second magnetic adsorption member 4140 and the electromagnetic adsorption member 4141 is provided.

[0108] In some embodiments, a sensor 416 electrically connected to the control module is further provided at one end of each chute 4110 away from the baffle 4111, and a sensor (not shown) is provided on the sample carrier bar 412. When the sample carrier bar 412 slides into the chute 4110 from the end, the sensor 416 will synchronously detect the sensor, and the sensor 416 is used to send a signal indicating that the sample carrier bar 412 has entered. Optionally, the sensor 416 is a photoelectric sensor, an infrared sensor, or a Hall sensor.

[0109] Furthermore, the sample carrier module 410 also includes a scanning terminal (not shown) disposed on one side of the sample base 411, the scanning terminal is located at one end of the sample base 411 away from the baffle 4111, and the scanning end of the scanning terminal is arranged toward the sample carrier bar 412. Each sample tube 20 is affixed with an information barcode for scanning and reading by the scanning terminal. A notch is provided on the side of the sample carrier bar 412 close to the scanning terminal corresponding to the positioning hole of each sample tube 20, and the notch can reveal the information barcode on the sample tube 20. Therefore, when the sample carrier bar 412 with the sample tube 20 is placed is pushed toward the baffle 4111 along the corresponding slide 4110, each sample tube 20 on the sample carrier bar 412 will be scanned by the scanning terminal in turn. Therefore, when the sensor 416 detects the sensing element, the control module obtains the signal of the sample carrier bar 412 entering from the sensor 416, and synchronously starts the scanning terminal to start scanning according to the signal. When the control module obtains the arrival signal sent by the corresponding detector 413, the control module controls the scanning terminal to stop scanning the code according to the arrival signal.

[0110] See also Figure 8 The sample clamping module 420 includes a sample clamping seat 421 and a sample clamping assembly 422. A receiving space is formed inside the clamping seat, and the sample clamping assembly 422 is arranged on the clamping seat and located in the receiving space. The sample clamping assembly 422 has two clamping heads 4220, and a clamping cavity 4221 for receiving the sample tube 20 is formed between the two clamping heads 4220. A clamping positioning hole 4210 is provided on the clamping seat, and the clamping positioning hole 4210 corresponds to the clamping cavity 4221.

[0111] Furthermore, the two opposite sides of the two clamps are provided with arc-shaped notches adapted to the outer wall of the sample tube 20, and the arc-shaped notches are provided with anti-slip structures. Optionally, the sample clamping assembly 422 can be a pneumatic clamp. The anti-slip structure is a rubber pad or anti-slip pattern.

[0112] See also Fig. 9 The gun head carrier module 430 includes a second push-pull assembly 431 and a gun head positioning frame 432, wherein the second push-pull assembly 431 is disposed on the frame 100; the gun head positioning frame 432 is disposed on the second push-pull assembly 431, and a plurality of third positioning parts for positioning the liquid taking gun head 30 are provided on the gun head positioning frame 432, wherein the second push-pull assembly 431 can drive the gun head positioning frame 432 to enter and exit the second feeding station 102. The structure of the second push-pull assembly 431 is consistent with that of the first push-pull assembly 311, and will not be described in detail in this embodiment.

[0113] See also Figure 3 In this embodiment, the sample supply module 400 also includes a sample recovery rack module 450, and the sample recovery rack module 450 has a recovery rack body 451. The recovery rack body 451 is detachably disposed on the rack 100 and is between the sample carrier module 410 and the sample clamping module 420. The recovery rack body 451 is used to collect the sample tube 20 after the sample is transferred to the consumable body 10.

[0114] In some embodiments, the sample recovery rack module 450 further includes a third push-pull assembly (not shown), and a plurality of fourth positioning portions are provided on the recovery rack body 451, and the fourth positioning portions are positioning holes. The third push-pull assembly can drive the recovery rack body 451 to enter and exit the second feeding station 102. The structure of the third push-pull assembly is consistent with that of the first push-pull assembly 311, and will not be described in detail here.

[0115] See also Figure 3 and Fig.10The biological sample automatic detection device further includes an ultrasonic vibration module 600, which is disposed at the processing station 103 and electrically connected to the control module. The ultrasonic vibration module 600 can selectively perform ultrasonic vibration on the consumable body 10 with the sample added thereto, that is, the ultrasonic vibration module 600 can be selected to be used according to the needs of sample detection.

[0116] The ultrasonic vibration module 600 includes an ultrasonic processing module 610 and an avoidance driving module 620. The avoidance driving module 620 is arranged on the work surface 110 of the frame 100, and the ultrasonic processing module 610 is arranged on the avoidance driving module 620. When the consumable transfer module 200 transfers the consumable body 10, the avoidance driving module 620 drives the ultrasonic processing module 610 to move out of the processing station 103 along the second horizontal direction Y. At this time, the entire ultrasonic processing module 610 is located in the avoidance space 120, so that the consumable transfer module 200 can grab the consumable body 10 on the ultrasonic processing module 610, prevent the consumable transfer module 200 from interfering with the first manipulator 320 and the second manipulator 440 on the stand 140, and play an avoidance role. When the consumable body 10 on the ultrasonic processing module 610 is taken away, the avoidance driving module 620 drives the ultrasonic processing module 610 to reset back to the processing station 103.

[0117] Specifically, the avoidance driving module 620 includes a base 621, a avoidance driving mechanism 622, a slide 623 and a third slide rail slider mechanism 624. The base 621 is arranged on the work surface 110 and is located at the processing station 103. The slide 623 is slidably arranged on the base 621 through the third slide rail slider mechanism 624, and the ultrasonic processing module 610 is arranged on the slide 623. The avoidance driving mechanism 622 is arranged on the base 621 and connected to the slide 623, and the avoidance driving mechanism 622 is used to drive the slide 623 to drive the ultrasonic processing module 610 to slide along the second horizontal direction Y.

[0118] Optionally, the avoidance drive mechanism 622 can be selected to be a pneumatic cylinder, an oil cylinder, an electric cylinder, an electric push rod, a linear motor or a motor screw.

[0119] The ultrasonic processing module 610 includes an ultrasonic mounting seat 611, an ultrasonic device 612, a lifting mechanism 613, a consumables clamping mechanism 614 and a positioning guide seat 615. The ultrasonic mounting seat 611 is arranged on the frame 100 and located at the processing station 103, and the positioning guide seat 615 is arranged on the ultrasonic mounting seat 611. A positioning groove 6150 is arranged on the positioning guide seat 615. A plurality of positioning guide blocks are arranged around the positioning groove 6150, and a side of the positioning guide block close to the positioning groove 6150 is a wedge-shaped surface. Among them, the plurality of positioning guide blocks and the positioning groove 6150 together form the first positioning portion.

[0120] Furthermore, an accommodating space 6101 is formed between the positioning guide seat 615 and the ultrasonic mounting seat 611, wherein the ultrasonic device 612 and the lifting mechanism 613 are both arranged in the accommodating space 6101, and the lifting mechanism 613 is connected to the ultrasonic device 612. The lifting mechanism 613 can drive the ultrasonic device 612 to rise and fall along the vertical direction Z so that the ultrasonic head of the ultrasonic device 612 can contact the bottom of the consumable body 10 placed on the first positioning portion, thereby performing ultrasonic vibration on the consumable body 10.

[0121] Optionally, the lifting mechanism 613 can be selected as a cylinder, an oil cylinder, an electric cylinder, an electric push rod, a linear motor or a motor screw. In this embodiment, the lifting mechanism 613 selects a through-type screw motor to save installation space and make the structure more compact.

[0122] The consumables clamping mechanism 614 includes a clamping drive assembly 6410 and two clamping arms 6141 arranged opposite to each other. The clamping drive assembly 6410 is arranged on the ultrasonic mounting seat 611. The two clamping arms 6141 are both arranged on the ultrasonic mounting seat 611 through a second slide rail and slider mechanism (not shown) and are both transmission-connected to the clamping drive assembly 6410. The clamping ends of the two clamping arms 6141 extend above the positioning guide seat 615, and the clamping ends are provided with clamping notches adapted to the outer circumference of the consumable body 10. The clamping drive assembly 6410 is used to drive the two clamping arms 6141 to move closer to or farther from each other, so as to clamp or release the consumable body 10.

[0123] Furthermore, the clamping drive assembly 6410 includes a clamping drive motor, a transmission gear and a transmission rack. Each clamping arm 6141 is provided with a transmission rack. The transmission racks on the two clamping arms 6141 are distributed along the radial direction of the transmission gear and mesh with the transmission gear. The motor shaft of the clamping drive motor is connected to the transmission gear, so that the transmission gear is driven to rotate forward and reversely by the clamping drive motor, and then the transmission gear is meshed with the two transmission racks to drive the two clamping arms 6141 to move closer to or away from each other.

[0124] See also Figures 1 to 10 This embodiment also provides a biological sample automatic detection method, which uses the biological sample automatic detection device provided above. The biological sample automatic detection method includes the following steps:

[0125] S100: placing a sample tube 20 containing a sample in the sample supply module 400, and pre-placing a consumable body 10 to be used on the consumable supply module 300;

[0126] S200: transferring at least one consumable body 10 to the processing station 103 for standby use through the consumable supply module 300;

[0127] S300: adding the sample in the sample tube 20 to the corresponding consumable body 10 through the sample supply module 400;

[0128] S400: The consumable body 10 with the sample added is transferred to the detection module 500 for detection by the consumable transfer module 200, and the consumable body 10 after detection is transferred to a designated area for disposal by the consumable transfer module 200. Specifically, a waste recycling box can be set under or on the side of the work surface 110 to collect the consumables after detection.

[0129] Compared with the prior art, the biological sample automatic detection device provided in this embodiment does not require manual participation in the subsequent detection process, and the supply of samples, the supply of the consumable body 10, and the addition of samples are all automatically performed at different stations, which greatly avoids the risk of contamination during the sample addition process. At the same time, the use of automated operation reduces manual labor intensity and improves detection efficiency.

[0130] It should also be noted that the biological sample automatic detection device provided in this embodiment is also provided with a hood with an open door structure (not shown) outside the frame 100, and the hood is provided to ensure a relatively closed environment during the detection process.

[0131] The above describes in detail the optional implementation methods of the embodiments of the present application in combination with the accompanying drawings. However, the embodiments of the present application are not limited to the specific details in the above implementation methods. Within the technical concept of the embodiments of the present application, various simple modifications can be made to the technical scheme of the embodiments of the present application, and these simple modifications all belong to the protection scope of the embodiments of the present application.

[0132] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the embodiments of the present application will not further describe various possible combinations.

[0133] In addition, the various implementation methods of the embodiments of the present application may be arbitrarily combined, and as long as they do not violate the ideas of the embodiments of the present application, they should also be regarded as the contents disclosed in the embodiments of the present application.

Claims

1. A biological sample automatic detection device, characterized in that: include: A frame (100), wherein a first feeding station (101), a second feeding station (102), a processing station (103) and a detection station (104) are provided on the frame (100), wherein the first feeding station (101), the processing station (103) and the second feeding station (102) are arranged in a first horizontal direction (X), and the detection station (104) is arranged in a second horizontal direction (Y); A consumable supply module (300) is arranged at the first feeding station (101), and is used to place the consumable body (10) and supply the consumable body (10) to the processing station (103); the processing station (103) is provided with a first positioning portion for positioning the consumable body (10); A sample supply module (400), arranged at the second feeding station (102), for placing a sample tube (20) and for adding the sample in the sample tube (20) to the consumable body (10) of the processing station (103); A detection module (500), arranged at the detection station (104), for detecting the consumable body (10) to which the sample is added; a consumable transfer module (200), arranged on the frame (100) and between the detection station (104) and the processing station (103), and used for transferring the consumable body (10) with the sample added thereto to the detection module (500); and A control module is used to control the coordinated work between the sample supply module (400), the consumable supply module (300), the detection module (500) and the consumable transfer module (200).

2. The biological sample automatic detection device according to claim 1, characterized in that: The consumables supply module (300) comprises: a consumable material carrier module (310), arranged on the frame (100) and located at the first feeding station (101), and used for placing the consumable material body (10) to be used; and The first robot (320) is arranged on the frame (100) and is used to grab the consumable body (10) and transfer it to the processing station (103).

3. The biological sample automatic detection device according to claim 2, characterized in that: The consumables carrier module (310) comprises: A first push-pull assembly (311) is disposed on the frame (100); and A consumable material positioning jig (312) is arranged on the first push-pull component (311), and the consumable material positioning jig (312) is provided with a second positioning portion (3120) for positioning the consumable material body (10), wherein the first push-pull component (311) can drive the consumable material positioning jig (312) to enter and exit the first feeding station (101).

4. The biological sample automatic detection device according to claim 1, characterized in that: The sample supply module (400) comprises: A sample carrier module (410), disposed on the rack (100), for placing a sample tube (20) containing a sample; A sample clamping module (420), disposed on the rack (100), and used for clamping the transferred sample tube (20); A gun tip carrier module (430), disposed on the frame (100) and used for placing a liquid extraction gun tip (30); and The second manipulator (440) is arranged on the frame (100), and the second manipulator (440) can move between the second feeding station (102) and the processing station (103). The second manipulator (440) includes a first gripper module (445) and a second gripper module (444), wherein the first gripper module (445) is used to grasp the sample tube (20) to transfer and screw the tube cover of the sample tube (20), and the second gripper module (444) is used to absorb the sample in the sample tube (20) by taking the corresponding liquid collection gun head (30) and add it to the consumable body (10).

5. The biological sample automatic detection device according to claim 4, characterized in that: The sample carrier module (410) comprises: A sample base (411) is disposed on the rack (100), the surface of the sample base (411) is provided with at least one slide groove (4110), and one end of the sample base (411) is provided with a baffle (4111); and At least one sample carrier bar (412), each of the sample carrier bars (412) is used to carry at least one sample tube (20), and the sample carrier bars (412) are slidably matched with the corresponding slide groove (4110); Wherein, the baffle (4111) is provided with a detector (413) electrically connected to the control module corresponding to each of the slide grooves (4110), and the sample carrier bar (412) is provided with a trigger member. When the sample carrier bar (412) slides along the corresponding slide groove (4110) and abuts against the baffle (4111), the trigger member triggers the detector (413), and the detector (413) sends out an in-place signal.

6. The biological sample automatic detection device according to claim 5, characterized in that: The sample carrier module (410) further includes a magnetic attraction component (414), and a first magnetic attraction component (415) is provided at one end of the sample carrier bar (412) facing the baffle (4111), and the baffle (4111) is provided with the magnetic attraction component (414) corresponding to each of the slide grooves (4110), and the magnetic attraction component (414) is used to attract each other with the first magnetic attraction component (415).

7. The biological sample automatic detection device according to claim 6, characterized in that: The magnetic attraction component (414) comprises a second magnetic attraction component (4140) and / or an electromagnetic attraction component (4141), wherein at least one of the second magnetic attraction component (4140) and the first magnetic attraction component (415) is a permanent magnet component.

8. The biological sample automatic detection device according to claim 4, characterized in that: The sample carrier module (410), the sample clamping module (420) and the gun tip carrier module (430) are distributed in sequence along the first horizontal direction (X).

9. The biological sample automatic detection device according to claim 4, characterized in that: The sample supply module (400) further comprises a sample recovery rack module (450), wherein the sample recovery rack module (450) is disposed on the rack (100) and between the sample carrier module (410) and the sample clamping module (420), and the sample recovery rack module (450) is used to collect the sample tube (20) after sample aspiration.

10. The biological sample automatic detection device according to claim 4, characterized in that: The gun tip carrier module (430) comprises: A second push-pull assembly (431) is disposed on the frame (100); and A gun tip positioning frame (432) is arranged on the second push-pull assembly (431), and a third positioning portion for positioning the liquid extraction gun tip (30) is provided on the gun tip positioning frame (432), wherein the second push-pull assembly (431) can drive the gun tip positioning frame (432) to enter and exit the second feeding station (102).

11. The biological sample automatic detection device according to claim 1, characterized in that: The consumable material transfer module (200) comprises a first driving module (210), a second driving module (220), a third driving module (230), a movable arm (240) and a third clamping claw module (250); the first driving module (210) is arranged on the frame (100); the second driving module (220) is arranged on the first driving module (210); the third driving module (230) is arranged on the second driving module (220); one end of the movable arm (240) is connected to the third driving module (230); and the other end is provided with the third clamping claw module (250); The first driving module (210) can drive the second driving module (220) to move along the first horizontal direction (X), the second driving module (220) can drive the third driving module (230) to move along the vertical direction (Z), the third driving module (230) can drive the movable arm (240) and drive the third clamping module (250) to rotate around an axis located in the vertical direction (Z), and the first driving module (210), the second driving module (220) and the third driving module (230) cooperate to enable the third clamping module (250) to grab the consumable body (10) for transfer.

12. The biological sample automatic detection device according to claim 1, characterized in that: The biological sample automatic detection device further comprises an ultrasonic vibration module (600), which is arranged at the processing station (103) and electrically connected to the control module, and the ultrasonic vibration module (600) can selectively perform ultrasonic vibration on the consumable body (10) to which the sample is added.

13. The biological sample automatic detection device according to claim 12, characterized in that: The ultrasonic vibration module (600) comprises an ultrasonic processing module (610) and an avoidance driving module (620), wherein the avoidance driving module (620) is arranged on the frame (100), and the ultrasonic processing module (610) is arranged on the avoidance driving module (620); When the consumable transfer module (200) transfers the consumable body (10), the avoidance drive module (620) drives the ultrasonic processing module (610) to move out of the processing station (103) along the second horizontal direction (Y).

14. A biological sample automatic detection method, characterized in that: The biological sample automatic detection device according to any one of claims 1 to 13 is applied, and the biological sample automatic detection method comprises: Placing the sample tube (20) containing the sample in the sample supply module (400), and pre-placing the consumable body (10) to be used on the consumable supply module (300); Transferring at least one of the consumable bodies (10) to the processing station (103) for standby use through the consumable supply module (300); Adding the sample in the sample tube (20) into the corresponding consumable body (10) through the sample supply module (400); The consumable body (10) with the sample added is transferred to the detection module (500) for detection through the consumable transfer module (200), and the consumable body (10) after detection is transferred to a designated area for disposal through the consumable transfer module (200).

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