Application of diethylene glycol phenyl ether and composition thereof

Abstract

The invention belongs to the technical field of cosmetics, and particularly relates to application of diethylene glycol phenyl ether and a composition thereof, diethylene glycol phenyl ether has the following advantages of no peculiar smell, good stability, good water solubility and good compatibility, and is a novel safe environment-friendly organic solvent. The diethylene glycol monophenyl ether composition comprises the following components: diethylene glycol monophenyl ether and an antibacterial moisturizing substance, wherein the mass ratio of the diethylene glycol phenyl ether to the antibacterial moisturizing substance is as follows: 45-65 parts of the diethylene glycol phenyl ether and the balance of the antibacterial moisturizing substance; the diethylene glycol monophenyl ether composition is obtained by mixing diethylene glycol monophenyl ether and an antibacterial moisturizing substance, the diethylene glycol monophenyl ether composition is applied to cosmetics and wet tissues for human bodies, and the cosmetics comprise emulsion type facial cleanser, moisturizing smoothing toner, whitening and freckle removing essence, body cream, facial cleanser, facial cleanser and shampoo. The MIC value of diethylene glycol phenyl ether is mostly lower than that of phenoxyethanol, the antibacterial effect of diethylene glycol phenyl ether is better than that of phenoxyethanol, and diethylene glycol phenyl ether is matched with p-hydroxyacetophenone, 1, 2-hexanediol, raspberry ketone and ethylhexylglycerin for use, so that the stability is good, the microbial activity can be inhibited, and the synergistic interaction effect is achieved.

Description

Technical Field

[0001] The invention relates to the technical field of cosmetics, in particular to application of diethylene glycol phenyl ether and a composition thereof. Background Art

[0002] Cosmetics: Preparations (except soap) applied to the human body to beautify, preserve, or alter one's appearance (e.g., for performance), or to cleanse, dye, polish, correct, or protect the skin, hair, nails, eyes, or teeth.

[0003] Cosmetics are classified by their effects: cleansing type; skin care type; basic type; beauty type; therapeutic type.

[0004] However, current cosmetic raw materials have the following defects: poor antibacterial effect, presence of odor, poor water solubility, poor compatibility, and instability. Summary of the invention

[0005] The object of the present invention is to provide an application of diethylene glycol phenyl ether and a composition thereof, so as to solve the problems of poor antibacterial and sterilization effect, presence of odor, poor water solubility, poor compatibility and instability proposed in the above-mentioned background technology.

[0006] To achieve the above object, the present invention provides the following technical solution: an application of diethylene glycol phenyl ether and a composition thereof, characterized in that the diethylene glycol phenyl ether composition comprises the following components:

[0007] Diethylene glycol phenyl ether, antibacterial moisturizing agent;

[0008] Among them, the weight proportion of diethylene glycol phenyl ether and antibacterial moisturizing agent is: 45-65 parts of diethylene glycol phenyl ether, and the rest is antibacterial moisturizing agent;

[0009] The diethylene glycol phenyl ether and the antibacterial moisturizing material are mixed to obtain a diethylene glycol phenyl ether composition. The diethylene glycol phenyl ether composition is applied to cosmetics and human wet wipes. The cosmetics include emulsion-type facial cleansers, moisturizing toners, whitening and anti-freckle essences, body creams, facial cleansing lotions, facial cleansing milks and shampoos.

[0010] Preferably, the antibacterial moisturizing substance includes p-hydroxyacetophenone and 1.2-hexanediol, and the weight ratios of diethylene glycol phenyl ether, p-hydroxyacetophenone and 1.2-hexanediol are: 50 parts of diethylene glycol phenyl ether, 30 parts of p-hydroxyacetophenone and 20 parts of 1.2-hexanediol.

[0011] Preferably, the antibacterial moisturizing substance includes raspberry ketone and ethylhexylglycerin, and the mass ratios of diethylene glycol phenyl ether, raspberry ketone and ethylhexylglycerin are respectively: 65 parts of diethylene glycol phenyl ether, 20 parts of raspberry ketone and 15 parts of ethylhexylglycerin.

[0012] Preferably, the antibacterial moisturizing substance includes p-hydroxyacetophenone and raspberry ketone, and the weight ratios of the diethylene glycol phenyl ether, p-hydroxyacetophenone and raspberry ketone are: 55 parts of diethylene glycol phenyl ether, 20 parts of p-hydroxyacetophenone and 25 parts of raspberry ketone.

[0013] Preferably, the antibacterial moisturizing substance includes p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin, and the mass proportions of diethylene glycol phenyl ether, p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin are respectively: 55 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 15 parts of 1.2-hexanediol, and 5 parts of ethylhexylglycerin.

[0014] Preferably, the antibacterial moisturizing substance includes p-hydroxyacetophenone, raspberry ketone, and 1.2-hexanediol, and the mass ratios of diethylene glycol phenyl ether, p-hydroxyacetophenone, raspberry ketone, and 1.2-hexanediol are: 45 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 20 parts of raspberry ketone, and 10 parts of 1.2-hexanediol.

[0015] Preferably, when the diethylene glycol phenyl ether composition is used, the diethylene glycol phenyl ether composition accounts for 0.1%-0.8% of the total mass of the cosmetic.

[0016] Compared with the prior art, the present invention has the following beneficial effects:

[0017] The MIC values ​​of diethylene glycol phenyl ether are mostly lower than those of phenoxyethanol, and its antibacterial effect is better than that of phenoxyethanol. Moreover, it has good stability when used in combination with p-hydroxyacetophenone, 1.2-hexanediol, raspberry ketone, and ethylhexylglycerin.

[0018] In addition, the use of diethylene glycol phenyl ether makes cosmetics have the following advantages: no odor, good water solubility and good solubility. DETAILED DESCRIPTION

[0019] The technical solutions in the embodiments of the present invention are described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0020] The present invention provides a technical solution: an application of diethylene glycol phenyl ether and a composition thereof, characterized in that the diethylene glycol phenyl ether composition comprises the following components:

[0021] Diethylene glycol phenyl ether, antibacterial moisturizing agent;

[0022] Among them, the weight proportion of diethylene glycol phenyl ether and antibacterial moisturizing agent is: 45-65 parts of diethylene glycol phenyl ether, and the rest is antibacterial moisturizing agent;

[0023] The diethylene glycol phenyl ether and the antibacterial moisturizing material are mixed to obtain a diethylene glycol phenyl ether composition. The diethylene glycol phenyl ether composition is applied to cosmetics and human wet wipes. The cosmetics include emulsion-type facial cleansers, moisturizing toners, whitening and anti-freckle essences, body creams, facial cleansing lotions, facial cleansing milks and shampoos.

[0024] The raw materials for preparing diethylene glycol phenyl ether include: phenol, alkaline catalyst, ethylene oxide, and diethylene glycol phenyl ether is prepared based on the reaction between phenol, alkaline catalyst and ethylene oxide.

[0025] Diethylene glycol phenyl ether has no odor. Odorless ingredients can prevent users from feeling unpleasant odors when using it, thereby improving the user experience and satisfaction. No odor also generally means being gentler on the skin, reducing the risk of skin discomfort or irritation. For brands, no odor means reducing the use of chemical ingredients, especially ingredients such as flavors and pigments that may be harmful to the skin, which makes consumers think that the product is safer. When the diethylene glycol phenyl ether composition is used, the diethylene glycol phenyl ether composition accounts for 0.1%-0.8% of the total mass of the cosmetic.

[0026] The antibacterial moisturizers are in five combinations, as follows:

[0027] The first type: the antibacterial moisturizing material includes p-hydroxyacetophenone and 1.2-hexanediol, and the weight ratios of diethylene glycol phenyl ether, p-hydroxyacetophenone and 1.2-hexanediol are respectively: 50 parts of diethylene glycol phenyl ether, 30 parts of p-hydroxyacetophenone and 20 parts of 1.2-hexanediol.

[0028] The second type: the antibacterial moisturizing substance includes raspberry ketone and ethylhexylglycerin, and the mass proportions of diethylene glycol phenyl ether, raspberry ketone and ethylhexylglycerin are: 65 parts of diethylene glycol phenyl ether, 20 parts of raspberry ketone and 15 parts of ethylhexylglycerin.

[0029] The third type: the antibacterial moisturizing substance includes p-hydroxyacetophenone and raspberry ketone, and the mass proportions of the diethylene glycol phenyl ether, p-hydroxyacetophenone and raspberry ketone are 55 parts of diethylene glycol phenyl ether, 20 parts of p-hydroxyacetophenone and 25 parts of raspberry ketone respectively.

[0030] The fourth type: the antibacterial moisturizing agent includes p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin. The mass proportions of diethylene glycol phenyl ether, p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin are: 55 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 15 parts of 1.2-hexanediol, and 5 parts of ethylhexylglycerin.

[0031] The fifth type: the antibacterial moisturizing material includes p-hydroxyacetophenone, 1.2-hexanediol, and raspberry ketone. The mass proportions of diethylene glycol phenyl ether, p-hydroxyacetophenone, raspberry ketone, and 1.2-hexanediol are: 45 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 20 parts of raspberry ketone, and 10 parts of 1.2-hexanediol.

[0032] In actual use, the effect is as follows:

[0033] The MIC values ​​of diethylene glycol phenyl ether are mostly lower than those of phenoxyethanol, and its antibacterial effect is better than that of phenoxyethanol. Moreover, it has good stability when used with other raw materials (there are stability tests). Currently, there are 5 formulas that have passed stability and applied to 9 products (rinse and resident types), with significant antibacterial effects (there are antiseptic challenge test data). The following examples show the antiseptic challenge test data of 5 formulas in various products, where the bacterial inoculation amount is 10 6 The inoculum size of the fungus was 10 5 .

[0034]

[0035]

[0036]

[0037] Diethylene glycol phenyl ether material also has the following advantages:

[0038] 1. No odor

[0039] Most cosmetic raw materials currently used have more or less smell, and odorless cosmetic raw materials are becoming increasingly important in daily chemical products. Odorless ingredients can prevent users from feeling unpleasant odors when using them, thereby improving user experience and satisfaction. Odorless also usually means being gentler on the skin and reducing the risk of skin discomfort or irritation. For brands, odorless means reducing the use of chemical ingredients, especially ingredients that may be harmful to the skin, such as fragrances and pigments, which makes consumers think that the products are safer.

[0040] 2. Good water solubility

[0041] The solubility of diethylene glycol phenyl ether in water is 35g / L according to the ECHA official website, while the solubility of phenoxyethanol in water is 25g / L. The solubility of diethylene glycol phenyl ether in water is greater than that of most alcohols with antiseptic and synergistic effects in the daily chemical industry (caprylyl glycol, 1,2-decanediol and ethylhexylglycerin, etc.).

[0042] 3. Good solubility

[0043] Diethylene glycol phenyl ether is a non-ionic ingredient. It is soluble in almost all ingredients of daily chemical raw materials and has very good stability. There are solubility test reports (p-hydroxyacetophenone, raspberry ketone, caprylhydroxamic acid, o-cymene-5-ol, chlorphenesin, and flavors are dissolved in water, glycerin, and diethylene glycol phenyl ether respectively. The conclusion is that compared with water and glycerin, diethylene glycol phenyl ether has stronger solubility.

[0044]

[0045] 4. Good safety

[0046] ①EWG score is 1, which is a safe green grade

[0047] ② Patch test experiment: 0.8% of the subjects had no adverse reactions and there were test reports

[0048] ③Toxicological safety test: There are acute oral or acute dermal toxicity tests, skin and eye irritation / corrosion tests, skin allergy tests, skin phototoxicity tests, skin photoallergy tests, mutagenicity tests, subchronic oral or subchronic dermal toxicity tests, and there are test reports. The test results show that diethylene glycol phenyl ether is safe as a cosmetic raw material under the recommended usage method and concentration.

[0049] Take the diethylene glycol phenyl ether composition for body cream as an example:

[0050] The following are the ingredients of body cream:

[0051]

[0052]

[0053] Process:

[0054] Disperse carbomer and xanthan gum with cold water, mix phase A, heat and dissolve to 80-85 degrees, keep warm for 20 minutes, stir evenly, then add diethylene glycol phenyl ether composition, the diethylene glycol phenyl ether composition accounts for 0.1%-0.8% of the total mass of the body cream.

[0055] Mix phase B and heat to 80-85 degrees, stirring until completely dissolved.

[0056] Add phase B to phase A, homogenize for 2 minutes, degas, stir and cool.

[0057] Cool down to 50 degrees and add phase C, stirring well.

[0058] Add D phase at 45 degrees, and the material can be discharged when it passes the inspection at 38 degrees.

[0059] The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention. For those skilled in the art, it is obvious that the present invention is not limited to the details of the above exemplary embodiments, and the present invention can be implemented in other specific forms without departing from the spirit or basic characteristics of the present invention; therefore, no matter from which point of view, the embodiments should be regarded as exemplary and non-restrictive. The scope of the present invention is limited by the attached claims rather than the above description, and it is intended to include all changes within the meaning and scope of the equivalent elements of the claims in the present invention.

[0060] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An application of diethylene glycol phenyl ether and a composition thereof, characterized in that: The diethylene glycol phenyl ether composition comprises the following components: Diethylene glycol phenyl ether, antibacterial moisturizing agent; Among them, the weight proportion of diethylene glycol phenyl ether and antibacterial moisturizing agent is: 45-65 parts of diethylene glycol phenyl ether, and the rest is antibacterial moisturizing agent; The diethylene glycol phenyl ether and the antibacterial moisturizing material are mixed to obtain a diethylene glycol phenyl ether composition. The diethylene glycol phenyl ether composition is applied to cosmetics and human wet wipes. The cosmetics include emulsion-type facial cleansers, moisturizing toners, whitening and anti-freckle essences, body creams, facial cleansing lotions, facial cleansing milks and shampoos.

2. The application of diethylene glycol phenyl ether according to claim 1 has no peculiar smell, good water solubility, good compatibility and good antibacterial effect, and is widely used in cosmetics as a matrix raw material.

3. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: The antibacterial moisturizing material comprises p-hydroxyacetophenone and 1.2-hexanediol, and the weight ratios of the diethylene glycol phenyl ether, p-hydroxyacetophenone and 1.2-hexanediol are as follows: 50 parts of diethylene glycol phenyl ether, 30 parts of p-hydroxyacetophenone and 20 parts of 1.2-hexanediol.

4. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: The antibacterial moisturizing substance includes raspberry ketone and ethylhexylglycerin. The mass proportions of diethylene glycol phenyl ether, raspberry ketone and ethylhexylglycerin are respectively: 65 parts of diethylene glycol phenyl ether, 20 parts of raspberry ketone and 15 parts of ethylhexylglycerin.

5. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: The antibacterial moisturizing substance comprises p-hydroxyacetophenone and raspberry ketone, wherein the weight ratios of diethylene glycol phenyl ether, p-hydroxyacetophenone and raspberry ketone are respectively: 55 parts of diethylene glycol phenyl ether, 20 parts of p-hydroxyacetophenone and 25 parts of raspberry ketone.

6. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: The antibacterial moisturizing substance includes p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin. The mass proportions of diethylene glycol phenyl ether, p-hydroxyacetophenone, 1.2-hexanediol, and ethylhexylglycerin are: 55 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 15 parts of 1.2-hexanediol, and 5 parts of ethylhexylglycerin.

7. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: The antibacterial moisturizing material includes p-hydroxyacetophenone, raspberry ketone, and 1.2-hexanediol. The mass proportions of diethylene glycol phenyl ether, p-hydroxyacetophenone, raspberry ketone, and 1.2-hexanediol are: 45 parts of diethylene glycol phenyl ether, 25 parts of p-hydroxyacetophenone, 20 parts of raspberry ketone, and 10 parts of 1.2-hexanediol.

8. The use of a diethylene glycol phenyl ether composition according to claim 1, characterized in that: When the diethylene glycol phenyl ether composition is used, the diethylene glycol phenyl ether composition accounts for 0.1%-0.8% of the total mass of the cosmetics.

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