Preparation method of hydrogel with tissue repair and anti-oxidation functions

Abstract

The invention discloses a preparation method of hydrogel with tissue repair and antioxidation functions, and the preparation method specifically comprises the following steps: a material preparation step: taking 10-50 parts by weight of gelatin powder, 5-10 parts by weight of alcohol, 20-100 parts by weight of a plant extract and 2-5 parts by weight of an antioxidant for later use; a mixing step: adding alcohol into the gelatin powder, and dissolving the gelatin powder to form a gelatin solution; and a gelation step: heating the plant extract, firstly adding the antioxidant into the plant extract, then slowly dropwise adding the gelatin solution into the plant extract to form a colloid mixture, and meanwhile, stirring to fully and uniformly mix the colloid mixture so as to avoid a caking phenomenon. When the hydrogel is prepared, the antioxidant and the plant extracting solution are added, so that the prepared hydrogel not only can play a role in moisturizing and moistening in cosmetics, but also can realize the functions of repairing damaged skin tissues and resisting skin oxidation.

Description

Technical Field

[0001] The invention relates to the technical field of hydrogel preparation, and in particular to a method for preparing a hydrogel with tissue repair and anti-oxidation functions. Background Art

[0002] Hydrogel is a commonly used additive in cosmetics. The hydrogel in cosmetics mainly has the functions of moisturizing, deep cleansing and nourishing the skin. It can form a protective film on the skin surface to help the skin lock in moisture, thereby improving uncomfortable symptoms such as dry skin and peeling.

[0003] Chinese patent application number 202310430277.7, a hydrogel for wound repair, a preparation method and application thereof, the hydrogel for wound repair forms a hydrogel with shape adaptability, self-healing and strong adhesion through multiple reversible bonds between polyvinyl alcohol, borax, oligomeric proanthocyanidins and trivalent iron ions, and can be quickly removed as needed.

[0004] The hydrogels currently used in cosmetics can only moisturize and relieve dryness, but cannot achieve tissue repair and anti-oxidation functions, resulting in a relatively single function of the hydrogel. Therefore, it is urgent to design a preparation method for hydrogels with tissue repair and anti-oxidation functions to solve the above problems. Summary of the invention

[0005] The purpose of the present invention is to provide a method for preparing a hydrogel with tissue repair and anti-oxidation functions to solve the above-mentioned deficiencies in the prior art.

[0006] In order to achieve the above object, the present invention provides the following technical solutions:

[0007] A method for preparing a hydrogel with tissue repair and anti-oxidation functions, wherein all raw materials are calculated by weight, specifically comprising the following steps:

[0008] Preparation steps: take 10-50 parts of gelatin powder, 5-10 parts of alcohol, 20-100 parts of plant extract and 2-5 parts of antioxidant for later use;

[0009] Mixing steps: add alcohol to gelatin powder to dissolve the gelatin powder to form a gelatin solution;

[0010] Gelation step: heating the plant extract, first adding the antioxidant into the plant extract, then slowly dropping the gelatin solution into the plant extract to form a colloidal mixture, stirring at the same time to fully mix it and avoid agglomeration;

[0011] Cooling step: cooling the colloidal mixture to room temperature, and pelletizing after the colloidal mixture solidifies;

[0012] Drying step: The granulated colloidal mixture is decompressed in a vacuum dryer to evaporate the water and remove it from the gel, thereby obtaining hydrogel particles.

[0013] Furthermore, in the material preparation step, the plant extract is prepared by the following steps:

[0014] S1: Take 10-50 portions of the Chinese medicinal material composition, chop them into small pieces, and then soak them in clean water for 0.5 h;

[0015] S2: putting the soaked Chinese medicinal material composition into a heating pot, adding 50-300 parts of clean water, heating and boiling for 1-3 hours, then pouring out the medicinal liquid A in the heating pot, and putting the remaining solid into a pressure vessel with a heating function, then adding 10-50 parts of clean water and 2-5 parts of mint again, and heating under high pressure for 0.5-1 hour to obtain medicinal liquid B;

[0016] S3: Mixing the medicinal solution A and the medicinal solution B, and concentrating them using a vacuum concentrator to obtain a Chinese herbal medicine extract, and then storing the obtained Chinese herbal medicine extract at a low temperature.

[0017] Furthermore, in the mixing step, when alcohol is added to the gelatin powder, the gelatin is stirred while the alcohol is added, and the stirring is performed alternately in a clockwise and counterclockwise direction.

[0018] Furthermore, in the gelling step, the plant extract is heated to 70° C.-80° C. and stirred at a speed of 60 r / min-80 r / min.

[0019] Furthermore, in the cooling step, a cold air fan is used for cooling, the air outlet speed of the cold air fan is 2m / s-10m / s, and the air outlet temperature of the cold air fan is 10℃-15℃.

[0020] Furthermore, in the drying step, the vacuum degree of the hydrogel particles during drying is -0.095 MPa, and the temperature during drying is 30-60°C.

[0021] Furthermore, in S1, the Chinese medicinal material composition is composed of salvia miltiorrhiza, liquorice and rehmannia glutinosa, and the weight ratio of salvia miltiorrhiza, liquorice and rehmannia glutinosa is 3:2:1.

[0022] Furthermore, in S2, the heating temperature of the pressure vessel is 110°C-120°C, and the pressure thereof is 50kPa-70kPa.

[0023] Furthermore, in the material preparation step, the antioxidant is one or a combination of two or more of vitamin E, coenzyme Q10 and malic acid.

[0024] In the above technical scheme, the present invention provides a method for preparing a hydrogel with tissue repair and antioxidant functions, and the beneficial effects are as follows: the present invention adds antioxidants and plant extracts when preparing the hydrogel, so that the prepared hydrogel can not only have a moisturizing effect in cosmetics, but also can achieve the repair of damaged skin tissue and skin antioxidant functions; the plant extract uses Salvia miltiorrhiza as a raw material, so that the hydrogel contains tanshinone, salvia miltiorrhiza phenol, danshensu, etc., and has the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, and antibacterial and anti-inflammatory effects; the plant extract uses licorice as a raw material, so that the hydrogel can promote wound healing, and can also relieve the pain of skin cracks and inhibit skin inflammation; the plant extract uses Rehmannia glutinosa as a raw material, so that the hydrogel has moisturizing, whitening, antioxidant, oil control and soothing effects. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments recorded in the present invention. For ordinary technicians in this field, other drawings can also be obtained based on these drawings.

[0026] Figure 1 The present invention provides a structural schematic diagram of a method for preparing a hydrogel having tissue repair and anti-oxidation functions according to an embodiment of the present invention. DETAILED DESCRIPTION

[0027] In order to enable those skilled in the art to better understand the technical solution of the present invention, Figure 1 The present invention is further described in detail.

[0028] Example 1

[0029] All raw materials are calculated by weight, and specifically include the following steps:

[0030] Preparation steps: take 10 parts of gelatin powder, 5 parts of alcohol, 40 parts of plant extract and 5 parts of antioxidant for later use, the antioxidant is a combination of vitamin E, coenzyme Q10 and malic acid, and the weight ratio of vitamin E, coenzyme Q10 and malic acid is 1:2:1, malic acid can accelerate the shedding of collagen cells, soften the stratum corneum of the skin, increase the collagen content of the skin, and effectively improve the phenomenon of dry skin; vitamin E has a strong antioxidant effect, can fight lipid peroxidation, and protect the skin from damage by free radicals; coenzyme Q10 can reduce the degradation of collagen fibers and prevent skin sagging and wrinkles;

[0031] Mixing steps: add alcohol to gelatin powder to dissolve the gelatin powder to form a gelatin solution. When adding alcohol to the gelatin powder, stir the gelatin while adding alcohol. Stir alternately clockwise and counterclockwise during stirring, such as stirring five circles clockwise first and then five circles counterclockwise, so that the mixing is more efficient.

[0032] Gelation step: heat the plant extract, first add the antioxidant into the plant extract, then slowly drip the gelatin solution into the plant extract to form a colloidal mixture, and stir it to mix it thoroughly and evenly to avoid agglomeration. Heat the plant extract to 80°C and stir at a speed of 60r / min.

[0033] Cooling step: Cool the colloid mixture to room temperature, and pelletize it after the colloid mixture solidifies. Use a cold air blower to cool it. The air outlet speed of the cold air blower is 10m / s, and the air outlet temperature of the cold air blower is 10°C, so that the cooling efficiency is higher.

[0034] Drying step: the granulated colloidal mixture is decompressed in a vacuum dryer to evaporate the water and remove it from the gel, thereby obtaining hydrogel particles. The vacuum degree of the hydrogel particles during drying is -0.095 MPa, and the drying temperature is 30-60°C.

[0035] Furthermore, in the material preparation step, the plant extract is prepared by the following steps:

[0036] S1: Take 10 portions of the Chinese herbal medicine composition, chop them, and then soak them in clean water for 0.5 hours. The Chinese herbal medicine composition is composed of salvia miltiorrhiza, liquorice and rehmannia root, and the weight ratio of salvia miltiorrhiza, liquorice and rehmannia root is 3:2:1. Salvia miltiorrhiza contains tanshinone, tanshinol, danshensu, etc., which have the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, and antibacterial and anti-inflammatory; liquorice can promote wound healing, and at the same time can also relieve the pain of skin cracking and inhibit skin inflammation; polysaccharides and flavonoids in rehmannia root can form a protective film on the skin surface, lock in moisture, prevent moisture loss, maintain the water and oil balance of the skin, and make the skin soft and moisturized. In addition, rehmannia root extract is rich in various nutrients, such as polysaccharides and amino acids, which can provide a long-lasting moisturizing effect, improve dry skin, make it softer and moisturized, and achieve a moisturizing effect; rehmannia root is rich in glycoside compounds, which can inhibit the production of melanin, fade spots, brighten the skin tone, and make the skin brighter and more translucent. Its active ingredients help to even out skin tone, reduce spots and dullness, make skin brighter and more even, and achieve a whitening effect; the flavonoids and polyphenols in Rehmannia have strong antioxidant properties, which can scavenge free radicals, reduce oxidative damage, and prevent skin aging. These ingredients can also promote the synthesis of collagen and elastin, increase skin elasticity, reduce the appearance of wrinkles and fine lines, make the skin firmer and younger, and achieve an antioxidant effect; Rehmannia extract promotes the growth of fibrin, indicating that it can enhance skin metabolism and change the composition of sebum. Its ability to absorb moisture in low-humidity environments makes it widely used in anti-oil, softening and moisturizing cosmetics. In addition, Rehmannia extract also has certain anti-swelling and soothing effects, which can reduce skin inflammatory reactions, relieve sensitivity and swelling, soothe the skin, improve skin condition, and achieve oil control and soothing effects;

[0037] S2: Put the soaked Chinese medicinal material composition into a heating pot, and add 50-300 parts of clean water to heat and boil for 1 hour, then pour out the medicinal liquid A in the heating pot, and put the remaining solid into a pressure vessel with a heating function, and then add 10 parts of clean water and 5 parts of mint again to heat under high pressure for 0.5 hours to obtain medicinal liquid B. The heating temperature of the pressure vessel is 110° C. and the pressure is 50 kPa. Mint can relieve skin discomfort, antibacterial and anti-inflammatory, and can also relieve skin inflammation and sensitivity, inhibit bacteria on the skin surface, and extract the effective ingredients in mint by pressure heating. On the one hand, it can prevent the mint extract from volatilizing, and on the other hand, it can extract the effective ingredients in mint to the maximum extent;

[0038] S3: Mixing the medicinal solution A and the medicinal solution B, and concentrating them using a vacuum concentrator to obtain a Chinese herbal medicine extract, and then storing the obtained Chinese herbal medicine extract at a low temperature.

[0039] Example 2

[0040] All raw materials are calculated by weight, and specifically include the following steps:

[0041] Preparation steps: take 10 parts of gelatin powder, 5 parts of alcohol, 40 parts of plant extract and 5 parts of antioxidant for later use, the antioxidant is a combination of vitamin E, coenzyme Q10 and malic acid, and the weight ratio of vitamin E, coenzyme Q10 and malic acid is 1:2:1, malic acid can accelerate the shedding of collagen cells, soften the stratum corneum of the skin, increase the collagen content of the skin, and effectively improve the phenomenon of dry skin; vitamin E has a strong antioxidant effect, can fight lipid peroxidation, and protect the skin from damage by free radicals; coenzyme Q10 can reduce the degradation of collagen fibers and prevent skin sagging and wrinkles;

[0042] Mixing steps: add alcohol to gelatin powder to dissolve the gelatin powder to form a gelatin solution. When adding alcohol to the gelatin powder, stir the gelatin while adding alcohol. Stir alternately clockwise and counterclockwise during stirring, such as stirring five circles clockwise first and then five circles counterclockwise, so that the mixing is more efficient.

[0043] Gelation step: heat the plant extract, first add the antioxidant into the plant extract, then slowly drip the gelatin solution into the plant extract to form a colloidal mixture, and stir it to mix it thoroughly and evenly to avoid agglomeration. Heat the plant extract to 80°C and stir at a speed of 60r / min.

[0044] Cooling step: Cool the colloid mixture to room temperature, and pelletize it after the colloid mixture solidifies. Use a cold air blower to cool it. The air outlet speed of the cold air blower is 10m / s, and the air outlet temperature of the cold air blower is 10°C, so that the cooling efficiency is higher.

[0045] Drying step: the granulated colloidal mixture is decompressed in a vacuum dryer to evaporate the water and remove it from the gel, thereby obtaining hydrogel particles. The vacuum degree of the hydrogel particles during drying is -0.095 MPa, and the drying temperature is 30-60°C.

[0046] Furthermore, in the material preparation step, the plant extract is prepared by the following steps:

[0047] S1: Take 30 parts of the Chinese herbal medicine composition, chop them, and then soak them in clean water for 0.5 hours. The Chinese herbal medicine composition is composed of salvia miltiorrhiza, liquorice and rehmannia root, and the weight ratio of salvia miltiorrhiza, liquorice and rehmannia root is 3:2:1. Salvia miltiorrhiza contains tanshinone, tanshinol, danshensu, etc., which have the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, and antibacterial and anti-inflammatory; liquorice can promote wound healing, and at the same time can also relieve the pain of skin cracking and inhibit skin inflammation; polysaccharides and flavonoids in rehmannia root can form a protective film on the skin surface, lock in moisture, prevent moisture loss, maintain the water and oil balance of the skin, and make the skin soft and moisturized. In addition, rehmannia root extract is rich in various nutrients, such as polysaccharides and amino acids, which can provide a long-lasting moisturizing effect, improve dry skin, make it softer and moisturized, and achieve a moisturizing effect; rehmannia root is rich in glycoside compounds, which can inhibit the production of melanin, fade spots, brighten the skin tone, and make the skin brighter and more translucent. Its active ingredients help to even out skin tone, reduce spots and dullness, make skin brighter and more even, and achieve a whitening effect; the flavonoids and polyphenols in Rehmannia have strong antioxidant properties, which can scavenge free radicals, reduce oxidative damage, and prevent skin aging. These ingredients can also promote the synthesis of collagen and elastin, increase skin elasticity, reduce the appearance of wrinkles and fine lines, make the skin firmer and younger, and achieve an antioxidant effect; Rehmannia extract promotes the growth of fibrin, indicating that it can enhance skin metabolism and change the composition of sebum. Its ability to absorb moisture in low-humidity environments makes it widely used in anti-oil, softening and moisturizing cosmetics. In addition, Rehmannia extract also has certain anti-swelling and soothing effects, which can reduce skin inflammatory reactions, relieve sensitivity and swelling, soothe the skin, improve skin condition, and achieve oil control and soothing effects;

[0048] S2: Put the soaked Chinese medicinal material composition into a heating pot, and add 50-300 parts of clean water to heat and boil for 1 hour, then pour out the medicinal liquid A in the heating pot, and put the remaining solid into a pressure vessel with a heating function, and then add 10 parts of clean water and 5 parts of mint again to heat under high pressure for 0.5 hours to obtain medicinal liquid B. The heating temperature of the pressure vessel is 110° C. and the pressure is 50 kPa. Mint can relieve skin discomfort, antibacterial and anti-inflammatory, and can also relieve skin inflammation and sensitivity, inhibit bacteria on the skin surface, and extract the effective ingredients in mint by pressure heating. On the one hand, it can prevent the mint extract from volatilizing, and on the other hand, it can extract the effective ingredients in mint to the maximum extent;

[0049] S3: Mixing the medicinal solution A and the medicinal solution B, and concentrating them using a vacuum concentrator to obtain a Chinese herbal medicine extract, and then storing the obtained Chinese herbal medicine extract at a low temperature.

[0050] Example 3

[0051] All raw materials are calculated by weight, and specifically include the following steps:

[0052] Preparation steps: take 10 parts of gelatin powder, 5 parts of alcohol, 40 parts of plant extract and 5 parts of antioxidant for later use, the antioxidant is a combination of vitamin E, coenzyme Q10 and malic acid, and the weight ratio of vitamin E, coenzyme Q10 and malic acid is 1:2:1, malic acid can accelerate the shedding of collagen cells, soften the stratum corneum of the skin, increase the collagen content of the skin, and effectively improve the phenomenon of dry skin; vitamin E has a strong antioxidant effect, can fight lipid peroxidation, and protect the skin from damage by free radicals; coenzyme Q10 can reduce the degradation of collagen fibers and prevent skin sagging and wrinkles;

[0053] Mixing steps: add alcohol to gelatin powder to dissolve the gelatin powder to form a gelatin solution. When adding alcohol to the gelatin powder, stir the gelatin while adding alcohol. Stir alternately clockwise and counterclockwise during stirring, such as stirring five circles clockwise first and then five circles counterclockwise, so that the mixing is more efficient.

[0054] Gelation step: heat the plant extract, first add the antioxidant into the plant extract, then slowly drip the gelatin solution into the plant extract to form a colloidal mixture, and stir it to mix it thoroughly and evenly to avoid agglomeration. Heat the plant extract to 80°C and stir at a speed of 60r / min.

[0055] Cooling step: Cool the colloid mixture to room temperature, and pelletize it after the colloid mixture solidifies. Use a cold air blower to cool it. The air outlet speed of the cold air blower is 10m / s, and the air outlet temperature of the cold air blower is 10°C, so that the cooling efficiency is higher.

[0056] Drying step: the granulated colloidal mixture is decompressed in a vacuum dryer to evaporate the water and remove it from the gel, thereby obtaining hydrogel particles. The vacuum degree of the hydrogel particles during drying is -0.095 MPa, and the drying temperature is 30-60°C.

[0057] Furthermore, in the material preparation step, the plant extract is prepared by the following steps:

[0058] S1: Take 50 parts of the Chinese herbal medicine composition, chop them, and then soak them in clean water for 0.5 hours. The Chinese herbal medicine composition is composed of salvia miltiorrhiza, liquorice and rehmannia root, and the weight ratio of salvia miltiorrhiza, liquorice and rehmannia root is 3:2:1. Salvia miltiorrhiza contains tanshinone, tanshinol, danshensu, etc., which have the effects of promoting blood circulation and removing blood stasis, clearing away heat and detoxifying, and antibacterial and anti-inflammatory; liquorice can promote wound healing, and at the same time can also relieve the pain of skin cracking and inhibit skin inflammation; polysaccharides and flavonoids in rehmannia root can form a protective film on the skin surface, lock in moisture, prevent moisture loss, maintain the water and oil balance of the skin, and make the skin soft and moisturized. In addition, rehmannia root extract is rich in various nutrients, such as polysaccharides and amino acids, which can provide a long-lasting moisturizing effect, improve dry skin, make it softer and moisturized, and achieve a moisturizing effect; rehmannia root is rich in glycoside compounds, which can inhibit the production of melanin, fade spots, brighten the skin tone, and make the skin brighter and more translucent. Its active ingredients help to even out skin tone, reduce spots and dullness, make skin brighter and more even, and achieve a whitening effect; the flavonoids and polyphenols in Rehmannia have strong antioxidant properties, which can scavenge free radicals, reduce oxidative damage, and prevent skin aging. These ingredients can also promote the synthesis of collagen and elastin, increase skin elasticity, reduce the appearance of wrinkles and fine lines, make the skin firmer and younger, and achieve an antioxidant effect; Rehmannia extract promotes the growth of fibrin, indicating that it can enhance skin metabolism and change the composition of sebum. Its ability to absorb moisture in low-humidity environments makes it widely used in anti-oil, softening and moisturizing cosmetics. In addition, Rehmannia extract also has certain anti-swelling and soothing effects, which can reduce skin inflammatory reactions, relieve sensitivity and swelling, soothe the skin, improve skin condition, and achieve oil control and soothing effects;

[0059] S2: Put the soaked Chinese medicinal material composition into a heating pot, and add 50-300 parts of clean water to heat and boil for 1 hour, then pour out the medicinal liquid A in the heating pot, and put the remaining solid into a pressure vessel with a heating function, and then add 10 parts of clean water and 5 parts of mint again to heat under high pressure for 0.5 hours to obtain medicinal liquid B. The heating temperature of the pressure vessel is 110° C. and the pressure is 50 kPa. Mint can relieve skin discomfort, antibacterial and anti-inflammatory, and can also relieve skin inflammation and sensitivity, inhibit bacteria on the skin surface, and extract the effective ingredients in mint by pressure heating. On the one hand, it can prevent the mint extract from volatilizing, and on the other hand, it can extract the effective ingredients in mint to the maximum extent;

[0060] S3: Mixing the medicinal solution A and the medicinal solution B, and concentrating them using a vacuum concentrator to obtain a Chinese herbal medicine extract, and then storing the obtained Chinese herbal medicine extract at a low temperature.

[0061] In the above-mentioned Example 1, Example 2 and Example 3, except for the number of portions of the Chinese medicine composition added, the other parameters are the same. Four groups of female experimenters were selected for the experiment, each group had 20 people, the age of the experimenters was between 30-38 years old, and the experimenters had tissue damage and aging problems on their faces. Three of the groups used the hydrogels obtained in Example 1, Example 2 and Example 3 to apply on their faces, and the remaining group used ordinary hydrogel to apply on their faces, both once in the morning and once in the evening every day. The experimental results obtained after 20 days of experiment are shown in the following table:

[0062]

[0063] From the comparison of the number of people who were satisfied with the private part flora reconstruction effect in the above table, it can be seen that the hydrogel finally obtained by Example 3 has the best effect.

[0064] The above description is only by way of illustration of certain exemplary embodiments of the present invention. It is undoubted that those skilled in the art can modify the described embodiments in various ways without departing from the spirit and scope of the present invention. Therefore, the above drawings and descriptions are illustrative in nature and should not be construed as limiting the scope of protection of the claims of the present invention.

Claims

1. A method for preparing a hydrogel with tissue repair and antioxidant functions, characterized in that: All raw materials are calculated by weight, and specifically include the following steps: Preparation steps: take 10-50 parts of gelatin powder, 5-10 parts of alcohol, 20-100 parts of plant extract and 2-5 parts of antioxidant for later use; Mixing steps: add alcohol to gelatin powder to dissolve the gelatin powder to form a gelatin solution; Gelation step: heating the plant extract, first adding the antioxidant into the plant extract, then slowly dropping the gelatin solution into the plant extract to form a colloidal mixture, stirring at the same time to fully mix it and avoid agglomeration; Cooling step: cooling the colloidal mixture to room temperature, and pelletizing after the colloidal mixture solidifies; Drying step: The granulated colloidal mixture is decompressed in a vacuum dryer to evaporate the water and remove it from the gel, thereby obtaining hydrogel particles.

2. The method for preparing a hydrogel with tissue repair and antioxidant functions according to claim 1, characterized in that: In the material preparation step, the plant extract is prepared by the following steps: S1: Take 10-50 portions of the Chinese medicinal material composition, chop them into small pieces, and then soak them in clean water for 0.5 h; S2: putting the soaked Chinese medicinal material composition into a heating pot, adding 50-300 parts of clean water, heating and boiling for 1-3 hours, then pouring out the medicinal liquid A in the heating pot, and putting the remaining solid into a pressure vessel with a heating function, then adding 10-50 parts of clean water and 2-5 parts of mint again, and heating under high pressure for 0.5-1 hour to obtain medicinal liquid B; S3: Mixing the medicinal solution A and the medicinal solution B, and concentrating them using a vacuum concentrator to obtain a Chinese herbal medicine extract, and then storing the obtained Chinese herbal medicine extract at a low temperature.

3. The method for preparing a hydrogel with tissue repair and antioxidant functions according to claim 1, characterized in that: In the mixing step, when alcohol is added to the gelatin powder, the gelatin is stirred while adding the alcohol, and the stirring is performed alternately in a clockwise and counterclockwise direction.

4. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 1, characterized in that: In the gelling step, the plant extract is heated to 70° C.-80° C. and stirred at a speed of 60 r / min-80 r / min.

5. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 1, characterized in that: In the cooling step, a cold air fan is used for cooling, the air outlet speed of the cold air fan is 2m / s-10m / s, and the air outlet temperature of the cold air fan is 10℃-15℃.

6. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 1, characterized in that: In the drying step, the vacuum degree of the hydrogel particles during drying is -0.095 MPa, and the temperature during drying is 30-60°C.

7. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 2, characterized in that: In S1, the Chinese medicinal material composition is composed of salvia miltiorrhiza, liquorice and rehmannia root, and the weight ratio of salvia miltiorrhiza, liquorice and rehmannia root is 3:2:

1.

8. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 2, characterized in that: In the step S2, the heating temperature of the pressure vessel is 110°C-120°C, and the pressure thereof is 50 kPa-70 kPa.

9. The method for preparing a hydrogel with tissue repair and anti-oxidation functions according to claim 1, characterized in that: In the material preparation step, the antioxidant is one or a combination of two or more of vitamin E, coenzyme Q10 and malic acid.

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