Production method of scutellaria baicalensis capsule
By adopting multiple decoction and precipitation treatments in the production of Scutellaria Baicalensis capsules, avoiding the use of ethanol extraction, and using the method of pulverizing in two steps, the problem of excessive process flow and excessive crushing time in the existing technology is solved, and efficient production and equipment life are achieved.
Patent Information
- Application Number
- CN202311259589.2
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-09-27
- Publication Date
- 2025-03-28
AI Technical Summary
The existing Scutellaria baicalensis need to be extracted with ethanol during the production process, resulting in too long process flow and affecting production efficiency. At the same time, the pulverization time of Scutellaria baicalensis is too long, affecting the service life of the equipment.
By using multiple decoction and precipitation treatments in the production of Scutellaria Baicalensis capsules, avoiding the use of ethanol extraction and simplifying the process flow; at the same time, a coarse crusher and a grinder are used to crush in two steps to reduce the working time of the grinder.
The production process of Scutellaria Baicalensis capsules has been simplified, production efficiency has been improved, equipment service life has been extended, and drug efficacy has been ensured.
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Figure CN119700856A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the technical field of capsule pharmaceutical manufacturing, and in particular to a method for producing a scutellaria baicalensis capsule. Background Art
[0002] Scutellaria baicalensis is a commonly used Chinese medicine. In the long development history of Chinese medicine, Scutellaria baicalensis has been prepared as a medicine and used to treat diseases for thousands of years. It is an important medicine in traditional Chinese herbal medicine. Scutellaria baicalensis is usually used as a medicine with its roots. It has the effects of clearing heat and dampness, purging fire and detoxifying, stopping bleeding, and calming the fetus. It is often used to treat colds, coughs, sore throats, diarrhea, dysentery and other diseases.
[0003] Since Scutellaria baicalensis is bitter and cold in nature, it can easily cause gastrointestinal irritation to patients who take it, leading to reactions such as nausea, vomiting, and diarrhea. In order to reduce the risk of Astragalus baicalensis irritation to patients' stomachs, some pharmaceutical factories choose to make Scutellaria baicalensis capsules by capsule loading. Usually, Chinese medicines such as Scutellaria baicalensis need to be extracted with ethanol in the process of making drug solutions, and it also takes time to remove the ethanol from the drug solution, which can easily lead to a long process flow and affect production efficiency. Summary of the invention
[0004] In order to simplify the process flow of Scutellaria baicalensis capsules and ensure the production efficiency of Scutellaria baicalensis capsules, the present application provides a production method of Scutellaria baicalensis capsules.
[0005] A method for producing a scutellaria baicalensis capsule, characterized in that it comprises the following steps:
[0006] S1: Select raw materials of Scutellaria baicalensis, wash them, weigh them and cut them into segments; prepare saturated alum solution in advance for standby use;
[0007] S2: adding water to the cut scutellaria raw material, heating it and decocting it several times, storing the liquid obtained after each decoction in the same place, filtering the liquid once before each storage, discarding the residue left after the last decoction, and letting the filtered liquid stand until the scutellaria raw material debris is completely precipitated;
[0008] S3: taking the upper layer of the Chinese medicine solution in step S2 and filtering it to remove the debris of the raw material of Scutellaria baicalensis, adding a saturated aqueous solution of alum to the obtained liquid and stirring it, and standing it for several hours after precipitation is complete, and then pouring off the clear liquid;
[0009] S4: adding some water to the precipitate obtained in step S3, stirring sufficiently, waiting for the precipitate to settle, and pouring off the upper liquid to retain the remaining precipitate;
[0010] S5: Repeat step S4 several times. When the poured liquid is taken for testing and no sulfate reaction is detected in the poured liquid, stop repeating step S4, retain the remaining precipitate, and hold the remaining precipitate in a container;
[0011] S6: placing the remaining precipitate in S5 in a tray and piling it up to a thickness of several centimeters, placing the tray and the precipitate in a vacuum drying device, drying the precipitate to become a dried Scutellaria baicalensis paste, and crushing and grinding the dried Scutellaria baicalensis paste several times to make a dried paste powder;
[0012] S7: Prepare starch slurry in advance, take a certain amount of dry paste powder and a certain amount of starch and dry mix them, add a certain amount of starch slurry while stirring after the dry mixing is uniform, and mix them thoroughly at the same time to obtain a soft material;
[0013] S8: sieving and drying the soft material into fine powder, filling the fine powder into capsule shells through a capsule filling machine, and then combining them into complete Scutellaria baicalensis capsules, and storing each Scutellaria baicalensis capsule for later use;
[0014] S9: polishing the capsule shells and preparing the materials, and packaging the Scutellaria baicalensis capsules in blister packing, bagging and box packaging.
[0015] Preferably, in S2, the number of times the Scutellaria baicalensis raw material is decocted and heated by the extraction tank is set to twice, the amount of water used in the first decoction is several times the weight of the Scutellaria baicalensis raw material, the amount of water used in the second decoction is several times the weight of the Scutellaria baicalensis raw material, and the amount of water used in the first decoction is more than that in the second decoction.
[0016] Preferably, during the process of decocting the Scutellaria baicalensis raw material in the extraction tank, the steam pressure in the extraction tank is set to be maintained between 0.1 and 0.2 MPa.
[0017] Preferably, in S5, the precipitate is loaded into an alcohol precipitation tank or a stirring tank and water is added, and S4 is repeated 2 to 3 times, and the volume of water added to the alcohol precipitation tank or the stirring tank each time is 3 to 5 times the volume of the precipitate.
[0018] Preferably, in S6, the thickness of the dried scutellaria baicalensis paste when placed on the tray is 2 to 3 cm, and the drying environment temperature of the dried scutellaria baicalensis paste is not higher than 60°C.
[0019] Preferably, the drying of the dried Scutellaria baicalensis paste is stopped when the moisture content of the dried Scutellaria baicalensis paste is 3% to 5%.
[0020] Preferably, in S6, the dried scutellaria baicalensis paste is coarsely crushed by a coarse crusher and then pulverized by a pulverizer.
[0021] Preferably, in S7, the dry mixing ratio of the dry paste powder and the starch mixture is in the range of 1:0.451 to 1:0.526, and the mixture of the dry paste powder and the starch is stirred by a mixer until the color is uniform; some starch is dissolved in cold water and then slowly added into boiling water, the proportion of starch in the starch slurry is 5%, and the pre-prepared starch slurry is added into the mixer, and the ratio of the dry paste powder starch mixture to the starch slurry is in the range of 1:0.1595 to 1:0.1311, 5%, and the mixer is stirred until the color is uniform.
[0022] Preferably, in S8, the soft material is processed by a granulator to obtain wet fine powder, which is then dried by a fluidized bed dryer. When the drying temperature in the fluidized bed dryer reaches 55-60°C, the equipment is shut down, and the moisture content of the fine powder after final drying is no higher than 5%.
[0023] Preferably, the fine powder is granulated to a size no larger than 30 mesh.
[0024] In summary, this application has at least the following beneficial technical effects:
[0025] 1. In the process of crushing, decocting, drying, crushing and finally making into capsule fine powder, there is no need to dissolve the effective substances through ethanol, which reduces the use of ethanol in the raw materials and does not need to remove ethanol. Therefore, the production steps of Scutellaria baicalensis capsules are simplified in the process flow, which is beneficial to ensure production efficiency.
[0026] 2. Directly crushing the dried Scutellaria baicalensis paste may cause the grinder to work for too long, thus affecting the service life of the equipment and prolonging the time of powder. The dried Scutellaria baicalensis paste is crushed in two steps by the coarse crusher and the grinder for coarse crushing and crushing, thereby reducing the working time of the grinder, which is beneficial to ensure the service life of the equipment and prolong the time of powder.
[0027] 3. The drying temperature of the fine powder should be terminated when it reaches 55-60℃ to reduce the effect of long drying time on the stability of the effective substances in the fine powder, which is beneficial to ensure the efficacy. BRIEF DESCRIPTION OF THE DRAWINGS
[0028] Figure 1 It is a process flow chart of the production method of Scutellaria baicalensis Capsules in the embodiment.
[0029] Figure 2 It is a schematic diagram of the installation structure of the extraction workshop.
[0030] Figure 3 It is a schematic diagram of the installation structure of the solid workshop.
[0031] Description of reference numerals:
[0032] 1. Extraction workshop; 11. Picking table; 12. Medicine cutting machine; 13. Circulating water cleaning machine; 14. Extraction tank; 141. Medicine delivery pipe; 15. Liquid storage tank; 16. Alcohol precipitation tank; 17. Mixing tank; 18. Coarse crusher; 19. Pulverizer; 10. Vacuum drying equipment; 2. Solid workshop; 21. Sandwich pot; 22. Trough mixer; 23. Swinging granulator; 24. Boiling dryer; 25. Two-dimensional motion mixer; 26. Capsule filling machine; 27. Capsule polishing machine; 28. Blister packaging machine; 3. Outsourcing workshop; 4. Class D clean area. DETAILED DESCRIPTION
[0033] The technical scheme in the embodiment of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiment of the present invention. Obviously, the described embodiment is only a part of the embodiment of the present invention, not all of the embodiments. Based on the embodiment of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0034] The following combination Figure 1-Figure 3 This application is described in further detail.
[0035] A production method of Scutellaria baicalensis capsule, referring to Figures 1 to 3 , including the following steps:
[0036] S1: The operator prepares 3340g of Scutellaria baicalensis and some starch according to the standard formula, and also prepares some alum. After the preparation is completed, the operator sorts the Scutellaria baicalensis raw materials at the picking operation table in the factory, removes some parts that are severely damaged, corrupt, and contain mud and sand, and weighs the Scutellaria baicalensis raw materials according to production requirements;
[0037] The operator puts the prepared raw material of Scutellaria baicalensis into the medicine cutting machine 12 for cutting. After the operator cuts the raw material of Scutellaria baicalensis into segments, the raw material of Scutellaria baicalensis is transferred to the circulating water cleaning machine 13 for rapid washing, so as to clean the impurities on the surface of the raw material segments of Scutellaria baicalensis and drain most of the water attached to the surface. The water used in the washing process is clean drinking water, and the raw material segments of Scutellaria baicalensis cannot fall to the ground during the washing process;
[0038] Take a container and dissolve alum in water in a ratio of 1:11.77. Cover the container and let it stand for 24 hours. Then take the clear liquid of the upper saturated alum solution and put it into another container for use.
[0039] S2: The raw material segment of Scutellaria baicalensis is transferred to the extraction tank 14, and water is added and heated for decoction twice. The first time, 10 times the weight of the raw material segment of Scutellaria baicalensis is added for decoction for 2 hours. After the time is reached, the extraction tank 14 is turned off and the medicinal liquid is taken out, and a 200-mesh screen is used for filtering. The filtrate is placed in the liquid storage tank 15. In this embodiment, the liquid storage tank 15 can be vertical or horizontal;
[0040] The raw material segments of Scutellaria baicalensis used in the first decoction are put back into the extraction tank 14, and 8 times of water as the raw material segments of Scutellaria baicalensis in the extraction tank 14 are added for decoction. After 2 hours of decoction, the extraction tank 14 is turned off to take out the medicinal liquid, and a 200-mesh sieve is used for filtration. The liquid part after filtration is incorporated into the medicinal liquid obtained by the first decoction, and the filtered raw material segments of Scutellaria baicalensis are obtained; the steam pressure of the two decoctions in the extraction tank 14 is 0.15Mpa; after the medicinal liquid in the storage tank 15 is static for 4 hours, the debris of the raw material of Scutellaria baicalensis is completely precipitated.
[0041] S3: Take the upper layer of the precipitated liquid in the liquid storage tank 15 in S2 and put it into the alcohol precipitation tank 16 or the stirring tank 17. While the internal liquid is being stirred in the alcohol precipitation tank 16 or the stirring tank 17, slowly add the saturated alum solution in S1 to the liquid. After the precipitation is complete, let it stand for 12 hours. At this time, the operator pours off the upper liquid.
[0042] S4: adding clean drinking water 3 to 5 times the weight of the precipitate to the precipitate in the alcohol precipitation tank 16 or the stirring tank 17 in step S3, stirring, waiting for the precipitate to re-precipitate completely, and pouring off the upper liquid.
[0043] S5: Step S4 is repeated 2 to 3 times until no sulfate reaction is detected in the decanted liquid, at which time a clean stainless steel container is used to contain the remaining precipitate.
[0044] S6: placing the precipitate in S5 in a tray, piling it up to a thickness of 2 to 3 cm, and placing the tray containing the precipitate in a vacuum drying device 10. The drying environment temperature of the precipitate in the vacuum drying device is not higher than 60°C, and the steam pressure is about 0.1 MPa. When the moisture content of the precipitate is 3 to 5%, the vacuum drying device 10 stops working, thereby obtaining the dried Scutellaria baicalensis paste; using a coarse crusher 18 and a toothed disc grinder 19 to coarsely crush the Scutellaria baicalensis paste and then finely grind it into dry paste powder, the dry paste powder is 80 mesh fine powder, and the dry paste powder is contained in a clean container for standby use.
[0045] S7: Put starch in a clean container, add an equal weight of cold purified water and stir to dissolve, then slowly add boiling purified water while stirring to make the starch account for 5%, thereby completing the preparation of 5% starch slurry, and stir until it is translucent and semi-solid to obtain a soft material, and let it cool for later use;
[0046] A certain amount of dry paste powder and a certain amount of starch are placed in a trough mixer 22 for dry mixing, the dry mixing ratio of the dry paste powder and the starch mixture is in the range of 1:0.451 to 1:0.526, after the two powders are dry mixed evenly, starch slurry is added while stirring, the ratio of the powder mixture to the starch slurry is in the range of 1:6.27 to 1:7.63, thereby obtaining a soft material;
[0047] S8: The soft material in S7 is placed in a swing granulator 23 and passed through a 30-mesh sieve to form wet fine powder. The wet fine powder is placed in a boiling dryer 24 for drying. As the moisture in the fine powder evaporates, the bed temperature gradually increases. When the temperature gauge on the boiling dryer 24 reads 55-60° C., the swing granulator 23 can be shut down and the fine powder can be released. At this time, the moisture content of the fine powder is controlled to be less than 5%, and the operator uses a clean container for storage;
[0048] The dried fine powder is granulated through an oscillating granulator 23 equipped with a 30-mesh screen, and then the same batch of fine powder is mixed in a mixer for 25 minutes, and the mixed fine powder is loaded into a clean container for standby use.
[0049] The mixed fine powder is transported to the hard capsule filling machine for preparation, and the diameter 0 hollow capsule is filled into the mold, which is installed on the filling machine after cleaning, disinfection and wiping. After the capsule filling machine 26 is debugged, the filling is carried out, and the capsule weight is tested at intervals of 20 minutes to ensure that the amount of fine powder in the capsule is between 0.3185 and 0.3815 g;
[0050] After the filled capsules are sieved to remove fine powder, the Huangqin capsules are placed in a pharmaceutical polishing machine and polished until the capsules are complete and smooth in appearance. After polishing and dust removal, the clean capsules are placed in a clean transfer barrel and covered for storage;
[0051] S9: After the capsules are sieved to remove the fine powder, they are placed in a polishing machine to complete the polishing of the capsule shells; each Scutellaria baicalensis capsule is successively inner-packaged by a blister packaging machine 28, and the operator then puts the blister packages with capsules in each cavity into an outer packaging box according to production requirements.
[0052] In an actual production plant, the method of the present application requires three groups of workshops to be implemented, including an extraction workshop 1, a solid workshop 2 and an outsourcing workshop 3. The extraction workshop 1 includes a picking table 11, a medicine cutting machine 12, a circulating water cleaning machine 13, a number of extraction tanks 14, a number of liquid storage tanks 15, a number of alcohol precipitation tanks 16, a number of mixing tanks 17, a coarse crusher 18, a pulverizer 19 and a vacuum drying equipment 10.
[0053] The extraction workshop 1 is configured as a three-story space, wherein a picking platform 11, a medicine cutting machine 12 and a circulating water cleaning machine 13 are all installed on the top floor. The operator removes some severely damaged, corrupted, muddy and sandy parts of the Scutellaria baicalensis raw material that do not meet the production requirements on the picking platform 11, and then transports the Scutellaria baicalensis to the medicine cutting machine 12, cuts the Scutellaria baicalensis raw material into sections by the medicine cutting machine 12, and then loads the Scutellaria baicalensis raw material sections into the circulating water cleaning machine 13 for washing and flushing, so as to clean the periphery of the Scutellaria baicalensis raw material sections.
[0054] The extraction tank 14 is in the middle space of the extraction workshop 1. Several medicine delivery pipes 141 are installed on the ground next to the circulating water cleaning machine 13. The top of each medicine delivery pipe 141 is trumpet-shaped. Each medicine delivery pipe 141 is passed through the highest floor of the extraction workshop 1, and the lower end is installed at the feed port of each extraction tank 14 (only one group of medicine delivery pipes 141 and extraction tank 14 are shown in the figure). The operator installs the Scutellaria baicalensis raw material segment into each extraction tank 14 through each medicine delivery pipe 141, so that the extraction tank 14 can decoct the Scutellaria baicalensis raw material segment twice.
[0055] Each extraction tank 14, each liquid storage tank 15, each alcohol precipitation tank 16, and each stirring tank 17 are installed on the lower layer of the extraction workshop 1 (only part of the equipment is shown in the figure). After the decoction in the extraction tank 14 is completed, the medicinal liquid is transferred to the liquid storage tank 15 through a pipeline. In this embodiment, the liquid storage tank 15 can be a vertical liquid storage tank 15 or a horizontal liquid storage tank 15. The actual situation depends on the production requirements. The operator controls the equipment to extract the upper layer of liquid in the liquid storage tank 15 into the alcohol precipitation tank 16 and the stirring tank 17. While stirring the liquid, a pre-prepared saturated alum solution is added to cause precipitation in the alcohol precipitation tank 16 and the stirring tank 17. When the precipitation is complete, a saturated alum solution is added to the precipitate and allowed to stand; water is added to the precipitate in the alcohol precipitation tank 16 and the stirring tank 17, and the liquid is discharged after stirring. This is repeated many times until no sulfate reaction occurs when the liquid is sampled, and the excess alum solution is washed away.
[0056] An independent Class D clean area 4 is set up in the middle space of the extraction workshop 1, and a coarse crusher 18, a pulverizer 19 and a vacuum drying equipment 10 are installed in the Class D clean area 4. The alcohol precipitation tank 16 and the stirring tank 17 obtain the remaining precipitate and transport it to the vacuum drying equipment 10 for drying, and then crush and pulverize it through the coarse crusher 18 and the pulverizer 19, and finally transport it to the solid workshop 2.
[0057] The solid workshop 2 is arranged on the same floor, and the solid workshop 2 includes a sandwich pot 21, a trough mixer 22, a swing granulator 23, a boiling dryer 24, a two-dimensional motion mixer 25, a capsule filling machine 26, a capsule polishing machine 27 and a blister packaging machine 28.
[0058] After the starch slurry is prepared in the sandwich pot 21, it is placed in a clean container for standby use. The operator first places the dry paste powder crushed by the pulverizer 19 and part of the starch in the trough mixer for even mixing. While the trough mixer is working, the starch slurry is added for secondary mixing to obtain a soft material, and then the soft material is transported to the swing granulator 23 and sieved into fine powder of no more than 30 mesh size. At this time, the soft fine powder has a relatively high humidity. The operator transfers the fine powder to the boiling dryer 24 for drying to obtain fine powder with lower humidity.
[0059] The fine powder produced in the same batch is mixed by a two-dimensional motion mixer 25, and then transported to a capsule filling machine 26 after mixing, where the fine powder is filled into a capsule shell and the capsule shell is closed for discharge. The discharged capsules are polished by a capsule polishing machine 27 after removing the surface powder, thereby meeting the production standards of the capsules; the capsules are transported to a blister packaging machine 28 for inner packaging to complete the blister packaging, i.e., inner packaging; in the solid workshop 2, except for the sandwich pot 21, the remaining equipment and processes need to be carried out in a Class D clean area 4. For cost savings, the remaining equipment in the solid workshop 2 except for the sandwich pot 21 can be installed in the same room as the coarse crusher 18, grinder 19 and vacuum drying equipment 10 of the extraction workshop 1, or can be installed in an independent area, and only needs to meet the requirements of the Class D clean area 4, so no specific limitation is made in the embodiment.
[0060] The blister packages containing capsules are transported to the outer packaging workshop, sorted according to specifications, and distributed to the packaging workers. After confirming that the integrity of the blister packages, relevant logos, barcodes, specifications and other items are correct, they are bagged, sealed, and the required information is printed on the bags. The bags are then placed in the boxes to complete the process.
[0061] In the description of the present invention, it should be noted that the directions or positional relationships indicated by the terms "inside", "front", "back", "left", "right", etc. are based on the directions or positional relationships shown in the accompanying drawings, or are the directions or positional relationships in which the inventive product is usually placed when in use. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific direction, be constructed and operated in a specific direction, and therefore cannot be understood as a limitation on the present invention.
[0062] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "disposed" and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal communication of two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
Claims
1. A method for producing a scutellaria capsule, characterized in that , including the following steps, S1: Select raw materials of Scutellaria baicalensis according to the standard formula, wash, weigh and cut into segments; prepare saturated alum solution in advance for standby use; S2: adding water to the cut scutellaria raw material, heating it and decocting it several times, storing the liquid obtained after each decoction in the same place, filtering the liquid once before each storage, discarding the residue left after the last decoction, and letting the filtered liquid stand until the scutellaria raw material debris is completely precipitated; S3: taking the upper layer of the Chinese medicine solution in step S2 and filtering it to remove the debris of the raw material of Scutellaria baicalensis, adding a saturated aqueous solution of alum to the obtained liquid and stirring it, and standing it for several hours after precipitation is complete, and then pouring off the clear liquid; S4: adding some water to the precipitate obtained in step S3, stirring sufficiently, waiting for the precipitate to settle, and pouring off the upper liquid to retain the remaining precipitate; S5: Repeat step S4 several times. When the poured liquid is taken for testing and no sulfate reaction is detected in the poured liquid, stop repeating step S4, retain the remaining precipitate, and hold the remaining precipitate in a container; S6: placing the remaining precipitate in S5 in a tray and piling it up to a thickness of several centimeters, placing the tray and the precipitate in a vacuum drying device (10), drying the precipitate to become a dried scutellaria baicalensis paste, and crushing and grinding the dried scutellaria baicalensis paste several times to make a dried paste powder; S7: Prepare starch slurry in advance, take a certain amount of dry paste powder and a certain amount of starch and dry mix them, add a certain amount of starch slurry while stirring after the dry mixing is uniform, and mix them thoroughly at the same time to obtain a soft material; S8: sieving and drying the soft material into fine powder, filling the fine powder into capsule shells through a capsule filling machine (26) to form complete Scutellaria baicalensis capsules, and storing each Scutellaria baicalensis capsule for later use; S9: polishing the capsule shells and preparing the materials, and packaging the Scutellaria baicalensis capsules in blister packing, bagging and box packaging.
2. The method for producing a scutellaria baicalensis capsule according to claim 1, characterized in that: In S2, the number of times the raw material of Scutellaria baicalensis is decocted and heated by the extraction tank (14) is set to be two times, the amount of water used for the first decoction is several times the weight of the raw material of Scutellaria baicalensis, the amount of water used for the second decoction is several times the weight of the raw material of Scutellaria baicalensis, and the amount of water used for the first decoction is more than the amount of water used for the second decoction.
3. The method for producing a scutellaria baicalensis capsule according to claim 2, characterized in that: During the process of decocting the scutellaria baicalensis raw material in the extraction tank (14), the steam pressure in the extraction tank (14) is set to be maintained between 0.1 and 0.2 MPa.
4. The method for producing a scutellaria baicalensis capsule according to claim 1, characterized in that: In S5, the precipitate is loaded into an alcohol precipitation tank (16) or a stirring tank (17) and water is added. S4 is repeated 2 to 3 times, and the volume of water added to the alcohol precipitation tank (16) or the stirring tank (17) each time is 3 to 5 times the volume of the precipitate.
5. The method for producing a scutellaria baicalensis capsule according to claim 1, characterized in that: In S6, the thickness of the dried scutellaria baicalensis paste when placed on a tray is 2 to 3 cm, and the drying environment temperature of the dried scutellaria baicalensis paste is no higher than 60°C.
6. The method for producing a scutellaria baicalensis capsule according to claim 5, characterized in that: The drying of the dried Scutellaria baicalensis paste is stopped when the moisture content of the dried Scutellaria baicalensis paste is 3% to 5%.
7. The method for producing a scutellaria baicalensis capsule according to claim 1, characterized in that: In S6, the dried scutellaria baicalensis extract is coarsely crushed by a coarse crusher (18) and then pulverized by a pulverizer (19).
8. The method for producing a scutellaria baicalensis capsule according to claim 7, characterized in that: In S7, the dry mixing ratio of the dry paste powder and the starch mixture is in the range of 1:0.451 to 1:0.526, and the mixture of the dry paste powder and the starch is stirred by a mixer until the color is uniform; some starch is dissolved in cold water, and then boiling water is slowly added, the starch ratio in the starch slurry is 5%, and the pre-made starch slurry is added to the mixer, and the ratio of the dry paste powder starch mixture to the starch slurry is in the range of 1:0.1595 to 1:0.1311, and the mixer is stirred until the color is uniform.
9. The method for producing a scutellaria baicalensis capsule according to claim 1, characterized in that: In S8, the soft material is processed by a pellet machine to obtain wet fine powder, which is then dried by a fluidizing dryer. When the drying temperature in the fluidizing dryer reaches 55-60°C, the equipment is shut down. The moisture content of the fine powder after final drying is no more than 5%.
10. The method for producing a scutellaria baicalensis capsule according to claim 9, characterized in that: The fine powder is granulated to a size not larger than 30 mesh.