Non-surgical method for quickly flattening sunken scars

Abstract

The invention discloses a non-surgical method for quickly flattening a depressed scar, and belongs to the technical field of scar repair, the method comprises the following steps: sequentially smearing composite vitamin powder and repair gel on the surface of the depressed scar of the skin, after the smearing is completed, pulling the depressed scar towards the outer side, the peripheral skin of the concave scar is squeezed towards the concave scar, pulling and squeezing are repeated for 3-5 times, after completion, the concave scar is smeared with mixed gel, after smearing is completed, the concave scar is massaged and continuously massaged, after completion, the concave scar is irradiated under an infrared physiotherapy lamp for 10-30 min, the pulling and squeezing steps are repeated in the irradiation process, and after completion, the concave scar is removed. According to the invention, the prepared compound vitamin powder, the repairing gel and the mixed gel are used for repairing the concave scars, and the compound vitamin powder, the repairing gel and the mixed gel have a synergistic effect.

Description

Technical Field

[0001] The invention belongs to the technical field of scar repair, and in particular relates to a method for rapidly flattening a depressed scar without surgery. Background Art

[0002] Wounds of degree two or above caused by scalds, burns, crush injuries, electric shocks, surgery and other causes are prone to leave scars after treatment. The proliferation of remaining scars often leads to deformities. Scar contracture deformities caused by deep burns on the hands often cause hand dysfunction, bringing inconvenience to the patient's life and work.

[0003] Patent No. CN201910767852.6 discloses a medical scar repair silicone gel dressing and preparation method, which is composed of the following raw materials in weight percentage: 5% to 30% polydimethylsiloxane, 3% to 20% emulsifier, 0.5% to 5% gel matrix, 1% to 15% scar lightening factor, 0.01% to 0.5% deodorant, 0.05% to 5% antibacterial agent, 5% to 10% antipruritic agent, 0.0001% to 0.1% anticontractile drug, 0.05% to 10% penetration enhancer, buffer system and purified water balance. The invention encapsulates anticontractile drugs composed of plant extracts, corticosteroid hormones, heparin sodium, papaverine hydrochloride and other smooth muscle relaxants in the gel, and absorbs the smooth muscle relaxants into the body through transdermal absorption, thereby inhibiting the excessive contraction of myofibroblasts, reducing the intensity of scar contracture, and achieving the purpose of preventing scar contracture.

[0004] When implementing the technical solution of this invention patent, there are at least the following defects: 1. It is impossible to effectively repair depressed scars; 2. The means of repair are relatively simple. Summary of the invention

[0005] The purpose of the present invention is to provide a non-surgical method for rapidly flattening depressed scars.

[0006] The purpose of the present invention can be achieved through the following technical solutions: A non-surgical method for rapidly flattening depressed scars comprises the following steps: Apply the multivitamin powder and repair gel on the surface of the depressed scar on the skin in turn. After applying, pull the depressed scar outwards, and then squeeze the skin around the depressed scar towards the depressed scar. Repeat the pulling and squeezing 3 to 5 times. After completion, apply the mixed gel to the depressed scar. After application, massage the depressed scar for 4 to 5 minutes. After completion, place the depressed scar under an infrared therapy lamp for 10 to 30 minutes. Repeat the pulling and squeezing steps during the irradiation process. After completion, the depressed scar repair process is completed.

[0007] Furthermore, the dosage ratio of the complex vitamin powder to the repair gel is 1 g: 2-3 mL.

[0008] Furthermore, the usage ratio of the repair gel and the mixed gel is 1 mL:1-4 mL.

[0009] Furthermore, the wavelength of the infrared therapy lamp is 700nm to 1400nm.

[0010] Furthermore, the multivitamin powder is prepared by the following steps: Vitamin B1, vitamin B2 and folic acid are mixed in a mass ratio of 2:2:1, and then ground through a 200-mesh sieve to obtain a complex vitamin powder.

[0011] Furthermore, the repair gel is prepared by the following steps: Carbomer 980 is added to purified water and swelled overnight to obtain a swollen carbomer solution. The swollen carbomer solution is then heated to 65-70°C. After the heating is completed, it is stirred at a constant temperature of 200 r / min for 50-60 min, and then homogenized at a speed of 2000 r / min for 4-5 min. After completion, a carbomer system is formed. Polysorbate 80 is added to the carbomer system, and then it is stirred at a constant temperature of 200 r / min for 10-20 min. Silicone is added thereto, and it is stirred at a constant temperature of 200 r / min for 10-20 min. Then, it is homogenized at a speed of 2000 r / min for 4-5 min. After the system is naturally cooled to room temperature, vitamin E, vitamin A, recombinant type III humanized collagen and recombinant bovine basic fibroblast growth factor gel are added thereto with stirring. After the addition is completed, it is stirred at a constant temperature of 200 r / min for 10-20 min to form a repair gel.

[0012] Furthermore, the dosage ratio of the purified water, carbomer 980, polysorbate 80, silicone, vitamin E, vitamin A, recombinant type III humanized collagen and recombinant bovine basic fibroblast growth factor gel is 100 mL: 1.2-2.0 g: 0.4-0.5 g: 5.5-7.5 g: 6.8-8.5 g: 8.2-11.5 g: 7.4-7.5 g: 12-20 g.

[0013] Furthermore, the mixed gel is prepared by the following steps: Epidermal growth factor gel, acidic fibroblast growth factor gel, basic fibroblast growth factor gel and platelet-derived growth factor gel were mixed in a mass ratio of 1:1:1:1 to obtain a mixed gel, and the mixed gel was placed in a constant temperature environment of 40-50° C. for use.

[0014] Beneficial effects of the present invention: The present invention provides a non-surgical method for rapidly flattening a depressed scar. Specifically, the present invention uses the compound vitamin powder, repair gel and mixed gel configured by the present invention to repair the depressed scar. The compound vitamin powder, repair gel and mixed gel have a synergistic effect, as follows: (1) Basis of complementary ingredients and synergistic effects: Multivitamin powder mainly contains vitamin B1, vitamin B2 and folic acid. These vitamins play a key role in cell metabolism, proliferation and anti-oxidation. The repair gel contains carbomer 980, polysorbate 80, silicone and a variety of ingredients that promote skin repair, such as vitamin E, vitamin A, recombinant humanized type III collagen and recombinant bovine basic fibroblast growth factor gel. Its main function is to provide a repair environment and direct tissue repair substances. The mixed gel is composed of epidermal growth factor gel (EGF), acidic fibroblast growth factor gel (AFGF), basic fibroblast growth factor gel (BFGF) and platelet-derived growth factor gel (PDGF), focusing on stimulating cell proliferation and angiogenesis, and promoting tissue regeneration in depressed scars. These three substances complement each other, laying the foundation for the synergistic repair of depressed scars.

[0015] (2) Synergistic effect of cell metabolism and proliferation: Synergy between multivitamin powder and repair gel: Vitamin B1 and vitamin B2 in multivitamin powder participate in the energy metabolism of cells, providing energy support for the recombinant humanized type III collagen and recombinant bovine basic fibroblast growth factor gel in the repair gel to function. Specifically, vitamin B1 participates in sugar metabolism and provides ATP for cell activities, while recombinant humanized type III collagen requires energy to drive related intracellular reactions during synthesis and deposition. At the same time, folic acid in multivitamin powder participates in cell DNA synthesis, promotes cell division and proliferation, and cooperates with fibroblast growth factor in the repair gel to accelerate the renewal of cells in scars and jointly promote tissue regeneration in depressed scars.

[0016] The repair gel and the mixed gel work together: The recombinant bovine basic fibroblast growth factor gel in the repair gel works together with the AFGF and BFGF in the mixed gel to stimulate the proliferation and migration of fibroblasts. Fibroblasts play a key role in the production of collagen and elastic fibers. While the repair gel provides a direct fibroblast growth stimulating component, the growth factor in the mixed gel further enhances this stimulation, allowing fibroblasts to more actively synthesize extracellular matrix in the depressed scars and fill the depressed areas. At the same time, the EGF in the mixed gel stimulates the proliferation and differentiation of epidermal cells, and works together with vitamin A and other ingredients in the repair gel to accelerate the formation of new epidermis and make the skin surface of the depressed scars smoother.

[0017] (3) Synergistic effect of restoring environment creation: The gel system formed by Carbomer 980 in the repair gel provides a stable carrier environment for various growth factors in the mixed gel. PDGF in the mixed gel induces angiogenesis, while polysorbate 80 in the repair gel can help these growth factors diffuse better in the local skin, allowing angiogenesis factors to play a more effective role and provide sufficient nutrition and oxygen for the repair of depressed scars.

[0018] (4) Synergistic effect in promoting absorption: During use, first apply the multivitamin powder and repair gel to the depressed scar and perform auxiliary massage, which can promote the absorption of the multivitamin powder and repair gel. The mixed gel is applied in a warm state, which can increase blood circulation in the depressed scar and further promote the absorption of the ingredients in the multivitamin powder and repair gel. At the same time, the mixed gel itself can also be better absorbed, so that the effective ingredients in the three substances can more fully exert their synergistic effect in the repair of depressed scars, accelerating the process of flattening depressed scars. DETAILED DESCRIPTION

[0019] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention. Example 1

[0020] A non-surgical method for rapidly flattening depressed scars comprises the following steps: (1) Raw material preparation: Multivitamin powder: Mix vitamin B1, vitamin B2 and folic acid in a mass ratio of 2:2:1, and then grind through a 200-mesh sieve to obtain multivitamin powder.

[0021] The above-mentioned compound vitamin powder contains vitamin B1, vitamin B2 and folic acid, wherein vitamin B1 helps to maintain normal sugar metabolism and nerve and heart function, and can provide energy support for cell metabolism during skin tissue repair; vitamin B2 participates in biological oxidation and energy generation in the body, and plays an important role in maintaining the integrity of the skin and mucous membranes, it can promote skin metabolism, accelerate the renewal of damaged skin cells, folic acid is an important raw material for cell synthesis of DNA, can promote cell division and proliferation, and plays a key role in skin tissue regeneration, especially for the new cell of depressed scars. The present invention mixes and grinds these vitamins into fine powder, and after passing through a 200-mesh sieve, it is easier for the skin to absorb, so as to better play their synergistic role in repairing depressed scars.

[0022] Repair gel: Carbomer 980 (Lubrizol Management (Shanghai) Co., Ltd.) was added to purified water, and the solution was swollen overnight to obtain a swollen carbomer solution. The swollen carbomer solution was then heated to 65°C. After the heating was completed, the solution was stirred at a constant temperature of 200 r / min for 50 min, and then homogenized at a speed of 2000 r / min for 4 min. After completion, a carbomer system was formed. Polysorbate 80 (Nanjing Will Pharmaceutical Group Co., Ltd.) was added to the carbomer system, and then the solution was stirred at a constant temperature of 200 r / min for 10 min. Silicone (Dow Corning) was added thereto, and the solution was stirred at a constant temperature of 200 r / min for 10 min, and then homogenized at a speed of 2000 r / min. After the system was homogenized at a high speed for 4 minutes and naturally cooled to room temperature, vitamin E, vitamin A, recombinant humanized collagen type III (Jiangsu Jiangshan Juyuan Biotechnology Co., Ltd.) and recombinant bovine basic fibroblast growth factor gel (Beifuxin) were added thereto with stirring. After the addition was completed, the system was stirred at a constant temperature of 200 r / min for 10 minutes to form a repair gel, wherein the amount ratio of purified water, carbomer 980, polysorbate 80, silicone, vitamin E, vitamin A, recombinant humanized collagen type III and recombinant bovine basic fibroblast growth factor gel was 100 mL: 1.2 g: 0.4 g: 5.5 g: 6.8 g: 8.2 g: 7.4 g: 12 g.

[0023] In the above repair gel, Carbomer 980 is first added to purified water to swell overnight, and then heated, stirred and homogenized. Carbomer 980 is a commonly used gel matrix. The gel system formed after swelling has good viscosity and plasticity. Heating to 65°C and stirring and homogenizing can make Carbomer 980 better dispersed in the system to form a uniform Carbomer system, providing a stable carrier for the subsequent addition of ingredients, which helps to maintain the uniform texture and stability of the repair gel.

[0024] Then, add polysorbate 80 to the carbomer system and stir. Polysorbate 80 is a non-ionic surfactant that can reduce the surface tension of the system, making it easier for the repair gel to spread on the skin surface. It can also improve the dispersibility of other ingredients in the gel, which helps to evenly distribute the active ingredients in the gel, thereby ensuring that when applied to depressed scars, each repair component can fully contact the scar tissue.

[0025] Next, add silicone and stir. Silicone plays many important roles in the repair gel. Silicone can form a protective film on the skin surface, reduce the evaporation of skin moisture, and maintain a moist environment on the skin at the scar. A moist environment is conducive to promoting cell migration and proliferation, accelerating scar repair. At the same time, this protective film can also prevent the invasion of harmful substances such as external bacteria, reduce the risk of infection, and create good conditions for the repair of depressed scars.

[0026] Finally, adding vitamin E and vitamin A to the repair gel can further enhance its antioxidant and skin cell repair effects. Recombinant humanized type III collagen is an important component of skin collagen. It can directly supplement the missing collagen in the scar, fill the depression, and make the structure of the scar tissue more complete. Recombinant bovine basic fibroblast growth factor gel can stimulate the proliferation and migration of fibroblasts. Fibroblasts are key cells for producing collagen and elastic fibers. Their activity can promote the regeneration and remodeling of scar tissue and enhance the repair effect of depressed scars.

[0027] Mixed gel: Mix epidermal growth factor gel (EGF), acidic fibroblast growth factor gel (AFGF), basic fibroblast growth factor gel (BFGF) and platelet-derived growth factor gel (PDGF) in a mass ratio of 1:1:1:1 to obtain a mixed gel, and then place the mixed gel in a constant temperature environment of 40-50°C for standby use.

[0028] The mixed gel is mixed with epidermal growth factor gel (EGF), acidic fibroblast growth factor gel (AFGF), basic fibroblast growth factor gel (BFGF) and platelet-derived growth factor gel (PDGF) in a mass ratio of 1:1:1:1. EGF can stimulate the proliferation and differentiation of epidermal cells, accelerate the formation of new epidermis, and fill the defects in depressed scars. AFGF and BFGF can promote the growth and activity of fibroblasts, increase the synthesis of collagen and other extracellular matrices, and help repair depressed tissues. PDGF can induce angiogenesis, provide sufficient nutrition and oxygen for scar repair, and also promote cell proliferation and migration. The mixed gel is placed in a constant temperature environment of 40 to 50°C for use. When applied, the warm gel can increase blood circulation in the depressed scar. This is because the increase in temperature will cause local blood vessels to dilate and blood flow to accelerate, making the effective ingredients in the mixed gel easier to absorb, thereby effectively repairing the depressed scar.

[0029] (2) Repair of depressed scars: Apply compound vitamin powder and repair gel in sequence on the surface of the depressed scar on the skin (hereinafter referred to as the depressed area), wherein the dosage ratio of compound vitamin powder and repair gel is 1g:2mL. After application, pull the depressed area outward, and then squeeze the skin around the depressed area toward the depressed area, repeat the pulling-squeezing 3 times. After completion, apply mixed gel to the depressed area, the dosage ratio of repair gel and mixed gel is 1mL:1mL. After application, massage the depressed area to promote the absorption of repair gel and mixed gel, and continue massaging for 4 minutes. After completion, irradiate the depressed area under an infrared therapy lamp (wavelength 700nm~1400nm) for 10 minutes, repeat the pulling-squeezing steps during the irradiation process, and after completion, complete the depressed scar repair process.

[0030] In the above repair process, applying compound vitamin powder and repair gel to the sunken scar and assisting with massage can promote the absorption of vitamin E, vitamin A and other ingredients in compound vitamin powder and repair gel. Massage can stimulate blood circulation in the skin, make skin cells more active, and enhance the skin's uptake of these nutrients and repair factors. At the same time, after applying the gel, using an infrared therapy lamp to irradiate the application area can penetrate the human dermis and further promote blood circulation. Improved blood circulation can deliver more nutrients and oxygen to the scar repair site, while taking away metabolic waste, promoting the healing of soft tissue injuries, and greatly increasing the absorption of gel and vitamins, thereby effectively promoting skin growth and repairing the stratum corneum, and ultimately improving the overall effect of repairing sunken scars. Example 2

[0031] A non-surgical method for rapidly flattening depressed scars comprises the following steps: (1) Raw material preparation: Multivitamin powder: Mix vitamin B1, vitamin B2 and folic acid in a mass ratio of 2:2:1, and then grind through a 200-mesh sieve to obtain multivitamin powder.

[0032] Repair gel: Carbomer 980 (Lubrizol Management (Shanghai) Co., Ltd.) was added to purified water, and swelled overnight to obtain a swollen carbomer solution, and then the swollen carbomer solution was heated to 70°C. After the heating was completed, it was stirred at a constant temperature of 200 r / min for 60 min, and then homogenized at a speed of 2000 r / min for 5 min. After completion, a carbomer system was formed, and polysorbate 80 (Nanjing Will Pharmaceutical Group Co., Ltd.) was added to the carbomer system, and then stirred at a constant temperature of 200 r / min for 20 min, and then silicone (Dow Corning) was added thereto, and stirred at a constant temperature of 200 r / min for 20 min, and then homogenized at 2000 r / min. The system was homogenized at a speed of 500 r / min for 5 minutes. After the system was naturally cooled to room temperature, vitamin E, vitamin A, recombinant humanized collagen type III (Jiangsu Jiangshan Juyuan Biotechnology Co., Ltd.) and recombinant bovine basic fibroblast growth factor gel (Beifuxin) were added thereto with stirring. After the addition was completed, the system was stirred at a constant temperature at a speed of 200 r / min for 20 minutes to form a repair gel, wherein the amount ratio of purified water, carbomer 980, polysorbate 80, silicone, vitamin E, vitamin A, recombinant humanized collagen type III and recombinant bovine basic fibroblast growth factor gel was 100 mL: 1.8 g: 0.4 g: 7 g: 8 g: 10.3 g: 7.5 g: 15 g.

[0033] Mixed gel: Mix epidermal growth factor gel (EGF), acidic fibroblast growth factor gel (AFGF), basic fibroblast growth factor gel (BFGF) and platelet-derived growth factor gel (PDGF) in a mass ratio of 1:1:1:1 to obtain a mixed gel, and then place the mixed gel in a constant temperature environment of 45°C for use.

[0034] (2) Repair of depressed scars: Apply compound vitamin powder and repair gel in sequence on the surface of the depressed scar on the skin (hereinafter referred to as the depressed area), wherein the dosage ratio of compound vitamin powder and repair gel is 1g:3mL. After application, pull the depressed area outward, and then squeeze the skin around the depressed area toward the depressed area, repeat the pulling-squeezing 5 times. After completion, apply mixed gel to the depressed area, the dosage ratio of repair gel and mixed gel is 1mL:2mL. After application, massage the depressed area to promote the absorption of repair gel and mixed gel, and continue massaging for 5 minutes. After completion, irradiate the depressed area under an infrared therapy lamp (wavelength 700nm~1400nm) for 30 minutes, repeat the pulling-squeezing steps during the irradiation process, and after completion, complete the depressed scar repair process. Example 3

[0035] A non-surgical method for rapidly flattening depressed scars comprises the following steps: (1) Raw material preparation: Multivitamin powder: Mix vitamin B1, vitamin B2 and folic acid in a mass ratio of 2:2:1, and then grind through a 200-mesh sieve to obtain multivitamin powder.

[0036] Repair gel: Carbomer 980 (Lubrizol Management (Shanghai) Co., Ltd.) was added to purified water, and the solution was swollen overnight to obtain a swollen carbomer solution. The swollen carbomer solution was then heated to 70°C. After the heating was completed, the solution was stirred at a constant temperature of 200 r / min for 60 min, and then homogenized at a speed of 2000 r / min for 5 min. After completion, a carbomer system was formed. Polysorbate 80 (Nanjing Will Pharmaceutical Group Co., Ltd.) was added to the carbomer system, and then the solution was stirred at a constant temperature of 200 r / min for 20 min. Silicone (Dow Corning) was added thereto, and the solution was stirred at a constant temperature of 200 r / min for 20 min, and then the solution was homogenized at a speed of 2000 r / min. The mixture was homogenized at high speed for 5 minutes. After the system was naturally cooled to room temperature, vitamin E, vitamin A, recombinant humanized type III collagen (Jiangsu Jiangshan Juyuan Biotechnology Co., Ltd.) and recombinant bovine basic fibroblast growth factor gel (Beifuxin) were added thereto with stirring. After the addition was completed, the mixture was stirred at a constant temperature at a speed of 200 r / min for 20 minutes to form a repair gel, wherein the amount ratio of purified water, carbomer 980, polysorbate 80, silicone, vitamin E, vitamin A, recombinant humanized type III collagen and recombinant bovine basic fibroblast growth factor gel was 100 mL: 2.0 g: 0.5 g: 7.5 g: 8.5 g: 11.5 g: 7.5 g: 20 g.

[0037] Mixed gel: Mix epidermal growth factor gel (EGF), acidic fibroblast growth factor gel (AFGF), basic fibroblast growth factor gel (BFGF) and platelet-derived growth factor gel (PDGF) in a mass ratio of 1:1:1:1 to obtain a mixed gel, and then place the mixed gel in a constant temperature environment of 50°C for standby use.

[0038] (2) Repair of depressed scars: Apply compound vitamin powder and repair gel in sequence on the surface of the depressed scar on the skin (hereinafter referred to as the depressed area), wherein the dosage ratio of compound vitamin powder and repair gel is 1g:3mL. After application, pull the depressed area outward, and then squeeze the skin around the depressed area toward the depressed area, repeat the pulling-squeezing 5 times. After completion, apply mixed gel to the depressed area, the dosage ratio of repair gel and mixed gel is 1mL:4mL. After application, massage the depressed area to promote the absorption of repair gel and mixed gel, and continue massaging for 5 minutes. After completion, irradiate the depressed area under an infrared therapy lamp (wavelength 700nm~1400nm) for 30 minutes, repeat the pulling-squeezing steps during the irradiation process, and after completion, complete the depressed scar repair process.

[0039] It should be noted that, in this article, terms such as "include", "comprises" or any other variations thereof are intended to cover non-exclusive inclusion, so that a process, method, article or equipment that includes a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or equipment.

[0040] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A non-surgical method for rapidly flattening depressed scars, characterized in that: The following steps are involved: Apply the multivitamin powder and repair gel on the surface of the depressed scar on the skin in turn. After applying, pull the depressed scar outwards, and then squeeze the skin around the depressed scar towards the depressed scar. Repeat the pulling and squeezing 3 to 5 times. After completion, apply the mixed gel to the depressed scar. After application, massage the depressed scar for 4 to 5 minutes. After completion, place the depressed scar under an infrared therapy lamp for 10 to 30 minutes. Repeat the pulling and squeezing steps during the irradiation process. After completion, the depressed scar repair process is completed.

2. A non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The dosage ratio of the compound vitamin powder to the repair gel is 1g:2-3mL.

3. The non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The usage ratio of the repair gel and the mixed gel is 1 mL:1-4 mL.

4. The non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The wavelength of the infrared therapy lamp is 700nm-1400nm.

5. The non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The multivitamin powder is prepared by the following steps: Vitamin B1, vitamin B2 and folic acid are mixed in a mass ratio of 2:2:1, and then ground through a 200-mesh sieve to obtain a complex vitamin powder.

6. The non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The repair gel is prepared by the following steps: Carbomer 980 is added to purified water and swelled overnight to obtain a swollen carbomer solution. The swollen carbomer solution is then heated to 65-70°C. After the heating is completed, it is stirred at a constant temperature of 200 r / min for 50-60 min, and then homogenized at a speed of 2000 r / min for 4-5 min. After completion, a carbomer system is formed. Polysorbate 80 is added to the carbomer system, and then it is stirred at a constant temperature of 200 r / min for 10-20 min. Silicone is added thereto, and it is stirred at a constant temperature of 200 r / min for 10-20 min. Then, it is homogenized at a speed of 2000 r / min for 4-5 min. After the system is naturally cooled to room temperature, vitamin E, vitamin A, recombinant type III humanized collagen and recombinant bovine basic fibroblast growth factor gel are added thereto with stirring. After the addition is completed, it is stirred at a constant temperature of 200 r / min for 10-20 min to form a repair gel.

7. The non-surgical method for rapidly flattening depressed scars according to claim 6, characterized in that: The dosage ratio of the purified water, carbomer 980, polysorbate 80, silicone, vitamin E, vitamin A, recombinant type III humanized collagen and recombinant bovine basic fibroblast growth factor gel is 100 mL: 1.2-2.0 g: 0.4-0.5 g: 5.5-7.5 g: 6.8-8.5 g: 8.2-11.5 g: 7.4-7.5 g: 12-20 g.

8. The non-surgical method for rapidly flattening depressed scars according to claim 1, characterized in that: The mixed gel is prepared by the following steps: Epidermal growth factor gel, acidic fibroblast growth factor gel, basic fibroblast growth factor gel and platelet-derived growth factor gel were mixed in a mass ratio of 1:1:1:1 to obtain a mixed gel, and the mixed gel was placed in a constant temperature environment of 40-50° C. for use.