Sample detection apparatus and control method thereof
When the control module of the sample detection device receives the sample detection instruction, the synchronous control detection module exits the dormant state and starts the sample detection operation. At the same time, the injection module immediately wakes up and performs the injection operation, solving the problem of low detection efficiency in the prior art and realizing a more efficient sample detection process.
Patent Information
- Application Number
- CN202311290220.8
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2023-09-28
- Publication Date
- 2025-03-28
AI Technical Summary
After exiting from the dormant state, the existing sample detection device needs to wait until all components fully resume the running state before performing sample detection, resulting in low detection efficiency.
A sample detection device is designed, including a sample injection module, a detection module and a control module. When the control module receives the sample detection instruction, the synchronous control detection module exits the sleep state and starts the sample detection job. At the same time, the injection module immediately wakes up and performs the injection action.
By starting part of the injecting module when the detection module exits the sleep state but has not yet fully exited, the situation where all components are fully exited before detection is avoided, and the efficiency of sample detection is improved.
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Figure CN119716099A_ABST
Abstract
Description
Technical Field
[0001] The present application relates to the field of detection technology, and in particular to a sample detection device and a control method thereof. Background Art
[0002] In the prior art, when a sample detection device is not needed, the sample detection device is usually put into a dormant state to reduce various consumption of the sample detection device and reduce waste.
[0003] When a sample detection device is required to perform a sample detection, it is usually necessary to wait for the sample detection device to exit from a dormant state before performing operations related to the sample detection operation, resulting in a problem of low sample detection efficiency. Summary of the invention
[0004] The main technical problem solved by this application is how to improve the efficiency of sample detection.
[0005] In order to solve the above technical problems, the first technical solution adopted in the present application is: a sample detection device, comprising: an injection module; a detection module, the detection module is used to detect the sample; a control module, which is respectively connected to the injection module and the detection module, and the control module is used to: in response to the detection module being in a sleep state and receiving a sample detection instruction, synchronously control the detection module to execute an exit sleep action and control the injection module to execute an injection action; after the exit sleep action is completed, control the detection module to perform sample detection.
[0006] Among them, the injection module includes: a conveying component; a first aspiration needle, which is only used for sucking liquid; the control module is also used to: in response to the detection module entering a dormant state, control the first aspiration needle to suck diluent to enable the detection module to enter a dormant state.
[0007] Among them, the detection module also includes a second pipette needle, which is used to inhale and spit out liquid; in response to the detection module entering a sleep state, the first pipette needle is controlled to inhale the diluent, so that the detection module enters a sleep state, including: in response to the detection module entering a sleep state, the second pipette needle is controlled to inhale the diluent and spit it into the reaction cup; the conveying component is controlled to convey the reaction cup to the sampling position; the first pipette needle is controlled to inhale the diluent in the reaction cup, so that the detection module enters a sleep state.
[0008] Among them, controlling the first pipette needle to absorb the diluent in the reaction cup to enable the detection module to enter a dormant state includes: controlling the first pipette needle to absorb part of the diluent in the reaction cup, and controlling the needle tip of the first pipette needle to be immersed in the remaining diluent in the reaction cup to enable the detection module to enter a dormant state.
[0009] Among them, the number of first pipette needles is more than two, and the more than two first pipette needles include a magnetic separation pipette needle and / or a waste liquid needle; the first pipette needle is controlled to absorb part of the diluent in the reaction cup, and the needle head of the first pipette needle is controlled to be immersed in the remaining diluent in the reaction cup, so that the detection module enters a dormant state, including: controlling each first pipette needle to absorb part of the diluent in the corresponding reaction cup, and controlling the needle head of each first pipette needle to be immersed in the remaining diluent in the corresponding reaction cup, so that the detection module enters a dormant state.
[0010] Among them, the sampling module includes: a conveying component, which is used for sample conveying; a sampling component, which is used for sample collection after completing the liquid flushing operation of its liquid circuit; a detection module is used for sample detection after completing the liquid flushing operation of its liquid circuit; in response to the detection module being in a dormant state and receiving a sample detection instruction, the detection module is synchronously controlled to execute an exit from dormancy action and the sampling module is controlled to execute an injection action, including: in response to the detection module being in a dormant state and receiving a sample detection instruction, the sampling component and the detection module are controlled to perform a liquid flushing operation of their liquid circuits; before the liquid flushing operation is completed, the conveying component is controlled to transport the sample to the corresponding sampling position; after the liquid flushing operation of the sampling component is completed, the sampling component is controlled to collect the sample at the sampling position; after the exit from dormancy action is completed, the detection module is controlled to perform sample detection, including: after the liquid flushing operation of the detection module is completed, the detection module is controlled to detect the collected sample.
[0011] Among them, the sampling module includes: a conveying component, which is used for sample conveying; a sampling component, which is used for sample collection; synchronously controlling the detection module to execute the exit from sleep action and controlling the sampling module to execute the sampling action, including: controlling the detection module to execute the exit from sleep action, and simultaneously controlling the conveying component to transport the sample tube or the sample rack carrying the sample tube to the sample suction position; after the exit from sleep action is completed, controlling the detection module to perform sample detection, including: after the exit from sleep action is completed, controlling the sampling component to collect samples from the sample tube at the sample suction position, and transporting the collected samples to the detection module, and controlling the detection module to perform sample detection on the samples; or, the sampling The component includes a liquid-pipetting needle, which is used to collect samples; the detection module is synchronously controlled to execute an exit-sleep action and the injection module is controlled to execute an injection action, including: controlling the detection module to execute an exit-sleep action, and simultaneously controlling the conveying component to convey the sample tube or the sample rack carrying the sample tube to the sample suction position; controlling the liquid-pipetting needle in the injection component to collect samples from the sample tube at the sample suction position, so as to suck the samples into the liquid-pipetting needle in the injection component for standby use; after the exit-sleep action is completed, controlling the detection module to perform sample detection, including: after the exit-sleep action is completed, controlling the liquid-pipetting needle in the injection component to convey the collected samples to the detection module, and controlling the detection module to perform sample detection on the samples.
[0012] Among them, the pipette needle includes: a first pipette needle, which is only used for sucking liquid; a second pipette needle, which is used for sucking and discharging liquid; synchronously controlling the detection module to execute the exit sleep action and controlling the injection module to execute the injection action, including: in response to the detection module being in a sleep state for a time period greater than a preset time threshold, then: controlling the detection module to execute the exit sleep action, and at the same time controlling the conveying component to convey the sample tube or the sample rack carrying the sample tube to the sample suction position; controlling the first pipette needle and the second pipette needle to suck diluent for cleaning; in response to the detection module being in a sleep state for a time period not greater than a preset time threshold, then: controlling the detection module to execute the exit sleep action, and at the same time controlling the conveying component to convey the sample tube or the sample rack carrying the sample tube to the sample suction position; controlling the pipette needle in the injection component to the sample suction position The sample tube at the sampling position is used for sample collection so as to absorb the sample into the pipette needle in the sampling assembly for standby use; after the exiting sleep action is completed, the detection module is controlled to perform sample detection, including: in response to the time length that the detection module is in the sleep state being greater than the preset time length threshold, then: after the exiting sleep action is completed and the first pipette needle and the second pipette needle are cleaned, the first pipette needle and / or the second pipette needle are controlled to collect samples from the sample tube at the sampling position, and the collected samples are transported to the detection module, and the detection module is controlled to perform sample detection on the samples; in response to the time length that the detection module is in the sleep state being not greater than the preset time length threshold, then: after the exiting sleep action is completed, the first pipette needle and / or the second pipette needle are controlled to transport the collected samples to the detection module, and the detection module is controlled to perform sample detection on the samples.
[0013] Among them, the control module is also used for: in response to not receiving any instruction within the first preset time after the detection module is turned on or after detection, outputting a prompt message; in response to the feedback information being an affirmative instruction input by the user, or the feedback information being no response from the user, controlling the detection module to enter a sleep state; in response to the feedback information being a negative instruction input by the user, re-outputting the prompt message at an interval of a second preset time, and in response to the output number of the prompt message being greater than a preset number threshold, controlling the detection module to enter a sleep state.
[0014] In order to solve the above technical problems, the second technical solution adopted in the present application is: a control method for a sample detection device, the sample detection device includes an injection module, a detection module and a control module, the detection module is used to detect the sample; the control method includes: in response to the detection module being in a sleep state and receiving a sample detection instruction, synchronously controlling the detection module to execute an exit sleep action and controlling the injection module to execute an injection action; after the exit sleep action is completed, controlling the detection module to perform sample detection.
[0015] The beneficial effect of the present application is that, different from the prior art, in the technical solution of the present application, when the sample detection device is in a sleep state, if a sample detection instruction input by the user is received, the detection module of the sample detection device is controlled to execute an exit-sleep action. Since the injection module can be awakened immediately and operate normally after receiving the sample detection instruction, the injection module can be controlled to start part of the sample detection operation before the detection module is exiting the sleep state but has not completely exited the sleep state, thereby avoiding the situation where the sample detection can only be performed after the detection module completely exits the sleep state, thereby improving the efficiency of sample detection. BRIEF DESCRIPTION OF THE DRAWINGS
[0016] In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the following briefly introduces the drawings required for use in the description of the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work.
[0017] Figure 1 It is a structural schematic diagram of an embodiment of the sample detection device of the present application;
[0018] Figure 2 It is a structural schematic diagram of an embodiment of the sample injection module of the present application.
[0019] Reference numerals: sample detection device 10 , detection module 11 , control module 12 , injection module 13 , transport component 131 , sampling component 132 , first aspiration needle 1321 , second aspiration needle 1322 . DETAILED DESCRIPTION
[0020] The present application is further described in detail below in conjunction with the accompanying drawings and examples. It is particularly noted that the following examples are only used to illustrate the present application, but are not intended to limit the scope of the present application. Similarly, the following examples are only some embodiments of the present application rather than all embodiments, and all other embodiments obtained by ordinary technicians in the field without making creative work are within the scope of protection of the present application.
[0021] Reference to "embodiments" herein means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described herein may be combined with other embodiments.
[0022] In the description of this application, it is necessary to explain that, unless otherwise clearly specified and limited, the terms "install", "set", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or connected through an intermediate medium. For ordinary technicians in this field, the above-mentioned specific meanings belonging to this application can be connected according to specific circumstances.
[0023] This application proposes a sample detection device, see Figure 1 , Figure 1 is a schematic diagram of the structure of an embodiment of the sample detection device of the present application. Figure 1 As shown, the sample detection device 10 includes a detection module 11 , a control module 12 and a sample injection module 13 .
[0024] The sample injection module 13 is used to transport and collect samples.
[0025] The detection module 11 is used to detect the sample.
[0026] Among them, the injection module 13 can specifically include components for transporting samples and components for collecting samples in the sample detection device 10, and the detection module 11 can specifically include components for detecting samples in the sample detection device 10 and multiple pipelines for connecting the various components, as well as other components or pipelines that can be used in the sample detection operation, which are not limited here.
[0027] After the sample detection device 10 is turned on, if the detection module 11 is in an idle state, the detection module 11 is usually controlled to execute a sleep action to enter a sleep state, so as to avoid the detection module 11 being in a running state for a long time, requiring too much related reagents to be supplemented or consuming too much power, thereby reducing resource waste.
[0028] Among all the components of the sample detection device 10, some components need a certain amount of time to recover from a dormant state to an operating state, such as components that need to flush liquid circuits to recover operation, such as the detection module 11, and some components can recover from a dormant state to an operating state immediately, such as components that transport test tubes containing samples, such as the injection module 13.
[0029] The control module 12 is connected to the injection module 13 and the detection module 11 respectively.
[0030] The control module 12 is used to: in response to the detection module 11 being in a dormant state and receiving a sample detection instruction, synchronously control the detection module 11 to execute an exit from dormancy action and control the injection module 13 to execute an injection action. After the exit from dormancy action is completed, the detection module 11 is controlled to perform sample detection.
[0031] Among them, a corresponding sample detection button may be provided on the sample detection device 10, and a corresponding sample detection instruction may be generated when the user presses the sample detection button. This is only an example, and the sample detection instruction may also be generated or transmitted by other methods, which is not limited here.
[0032] In addition, when the sample detection device 10 is in the sleep state, the user can obtain various types of data, such as viewing instrument test results, printing reports, creating new task orders and other routine operations, without exiting the sleep state of the sample detection device 10.
[0033] When the detection module 11 is in the dormant state, if a sample detection instruction input by the user is received, the detection module 11 can be controlled to start executing the exit-dormant action, that is, to start the process of recovering from the dormant state to the running state, and the injection module 13 can be controlled to start the sample injection action before the exit-dormant action is completed. For example, the sample can be first transported to the corresponding sampling position, or the sample and the reagent can be first mixed, or the sample can be first temperature-controlled, etc., which are not limited here. Subsequently, after the exit-dormant action is completed, the detection module 11 is controlled to perform sample detection.
[0034] Based on the above method, the speed of performing sample detection in response to sample detection instructions when each module in the sample detection device 10 is in a sleep state can be improved, without the need to perform sample detection after all components of the sample detection device 10 exit the sleep state, thereby improving the efficiency of sample detection.
[0035] Different from the prior art, in the technical solution of the present application, when the sample detection device is in a sleep state, if a sample detection instruction input by the user is received, the detection module of the sample detection device is controlled to execute an exit from sleep mode. Since the injection module can be awakened immediately and operate normally after receiving the sample detection instruction, the injection module can be controlled to start part of the sample detection operation before the detection module is exiting the sleep state but has not completely exited the sleep state, thereby avoiding the situation where the sample detection can only be performed after the detection module completely exits the sleep state, thereby improving the efficiency of sample detection.
[0036] In practice, the sample detection device usually can only perform operations related to sample detection after it is fully started, that is, after the sample detection device exits sleep, such as triggering the start detection button, executing the injection action, and providing the corresponding setting list. Since the sample detection device takes a long time to exit sleep, the user often needs to continue to pay attention to the instrument status in order to start the detection in time when the instrument exits sleep, which greatly consumes the user's time and provides a poor user experience; if the instrument status cannot be continuously paid attention to, the detection cannot be started in time, resulting in low sample detection efficiency.
[0037] In the technical solution of the present application, when the control detection module starts to execute the exit sleep action, a corresponding setting list can be provided to the user, and the above-mentioned injection action and sample detection operations can be performed based on the setting list subsequently. Based on the above method, the time the user waits for the setting list provided by the sample detection device to appear can be reduced, thereby improving the user experience.
[0038] In one embodiment, see Figure 2 , Figure 2 Schematic diagram of the structure of an embodiment of the sample injection module of the present application. Figure 2 As shown, the injection module 13 includes a conveying component 131 and a sampling component 132 .
[0039] The sampling component 132 includes a first liquid aspiration needle 1321, and the first liquid aspiration needle 1321 is only used for aspirating liquid.
[0040] The control module 12 is also used for:
[0041] In response to the detection module 11 about to enter the sleep state, the first liquid aspiration needle 1321 is controlled to aspirate the diluent, so that the detection module 11 enters the sleep state.
[0042] Specifically, Figure 2 As shown, the first aspiration needle 1321 can specifically be aspiration needle used only for aspirating liquid, and can be aspiration needle whose internal structure only supports aspiration but not exhalation, such as a magnetic separation aspiration needle, or a waste liquid needle, or other types of aspiration needles that can only aspirate liquid.
[0043] When the first aspiration needle 1321 is in operation, it needs to be filled with a corresponding liquid, which is generally a diluent, but can also be other liquids in special cases. The liquid is used to be pushed by a corresponding power device to drive the corresponding reagent or sample to move in the liquid path through the liquid.
[0044] Therefore, by controlling the first aspiration needle 1321 to absorb the diluent when the detection module 11 is controlled to enter the sleep state, the first aspiration needle 1321 can be filled with all or part of the liquid space when it needs to exit the sleep mode later. Even if it is still necessary to replenish the liquid to ensure that it recovers to the operating state, the time for replenishing the liquid can be reduced as much as possible, thereby improving the timeliness of the detection module 11 recovering from the sleep state to the operating state to start the corresponding sample detection operation, thereby improving the efficiency of sample detection.
[0045] In addition, the detection module 11 can specifically be a flow chamber or other types of components with sample detection functions, which are not limited here. The control module 12 can also be used to: in response to the detection module 11 entering a dormant state, control the detection module 11 to inhale the diluent, so that the detection module 11 enters a dormant state. When the detection module 11 is in the operating state, it also needs to be filled with corresponding liquid. Therefore, based on the same reasons as the first aspiration needle 1321 mentioned above, based on the above method, the efficiency of sample detection can also be improved.
[0046] Optionally, the sampling component 132 further includes a second liquid aspiration needle 1322, which is used for aspirating and discharging liquid.
[0047] In response to the detection module 11 being about to enter the dormant state, the first liquid aspiration needle 1321 is controlled to aspirate the diluent, so that the detection module 11 enters the dormant state, including:
[0048] In response to the detection module 11 entering the dormant state, the second liquid aspirating needle 1322 is controlled to aspirate the diluent and spit it into the reaction cup.
[0049] The transport component 131 is controlled to transport the reaction cup to the sampling position.
[0050] The first liquid aspiration needle 1321 is controlled to aspirate the diluent in the reaction cup, so that the detection module 11 enters a dormant state.
[0051] Specifically, the second aspiration needle 1322 can be a sampling needle or other types of aspiration needles that can perform aspiration and exhalation, which is not limited here.
[0052] The diluent can be firstly sucked from the corresponding diluent storage component through the second aspiration needle 1322, and then the diluent can be spit into the reaction cup. At this time, the second aspiration needle 1322 can also be controlled to inject an appropriate amount of water or other liquid into the diluent to dilute the diluent to a suitable concentration.
[0053] The reaction cup containing the diluent can be moved to the sampling position corresponding to the first liquid-sucking needle 1321, and the first liquid-sucking needle 1321 is controlled to suck the diluent in the reaction cup, so that the detection module 11 enters the dormant state.
[0054] Based on the above method, in a reaction cup commonly used only in sample testing, the diluent can be transported to the sampling position corresponding to the first aspiration needle 1321 for aspiration, so that the first aspiration needle 1321 is filled with liquid when in a dormant state, thereby improving the efficiency of subsequent sample testing and avoiding the addition of other components to store the diluent, thereby reducing costs.
[0055] Further, controlling the first liquid aspiration needle 1321 to aspirate the diluent in the reaction cup so that the detection module 11 enters a dormant state includes:
[0056] The first aspiration needle 1321 is controlled to aspirate part of the diluent in the reaction cup, and the needle head of the first aspiration needle 1321 is controlled to be immersed in the remaining diluent in the reaction cup, so that the detection module 11 enters the dormant state.
[0057] Specifically, since the first liquid suction needle 1321 can only be used to suck liquid, if the outer part of the needle hole is stained with contaminants, it cannot remove the contaminants by spitting out liquid by itself, which easily causes the hole to be blocked, making the first liquid suction needle 1321 unable to operate normally. In the prior art, when the detection module 11 is restored to the operating state after a long period of dormancy, the possibility of such a hole blocking phenomenon is very high.
[0058] By only controlling the first pipette needle 1321 to absorb part of the diluent in the reaction cup, a part of the diluent can still be reserved in the reaction cup. At this time, the needle hole of the first pipette needle 1321 can also be controlled to be immersed in the remaining diluent in the reaction cup, and this state is maintained to put the detection module 11 into a dormant state. Based on the above method, contaminants other than the first pipette needle 1321 can be reduced, and the possibility of blocking the needle hole of the first pipette needle 1321 from the outside when the detection module 11 is in a dormant state can be reduced, thereby improving the reliability of the sample detection device 10.
[0059] Furthermore, the number of the first aspiration needles 1321 is more than two, and the more than two first aspiration needles 1321 include magnetic separation aspiration needles and / or waste liquid needles.
[0060] Controlling the first aspiration needle 1321 to aspirate part of the diluent in the reaction cup, and controlling the needle head of the first aspiration needle 1321 to be immersed in the remaining diluent in the reaction cup, so that the detection module 11 enters a dormant state, includes:
[0061] Each first aspiration needle 1321 is controlled to absorb part of the diluent in the corresponding reaction cup, and the needle head of each first aspiration needle 1321 is controlled to be immersed in the remaining diluent in the corresponding reaction cup, so that the detection module 11 enters the dormant state.
[0062] Specifically, the number of the first aspiration needles 1321 can be two, three, ten or other numbers, which are not limited here. For example, it can be a combination of two magnetic separation aspiration needles and one waste liquid needle. The transport component 131 can transport the reaction cup containing the diluent to the magnetic separation disk for the magnetic separation aspiration needle and the waste liquid needle to aspirate.
[0063] Each first aspiration needle 1321 is respectively configured with a corresponding reaction cup, and one reaction cup is used for one first aspiration needle 1321 to aspirate diluent and soak the needle port, so that each first aspiration needle 1321 can aspirate diluent and soak the needle port in its corresponding dormant position, and can also reduce the possibility of mutual contamination between samples, reagents or waste liquids aspirated by different aspiration needles, thereby further improving the reliability of the sample detection device.
[0064] In one embodiment, if Figure 2 As shown, the injection module 13 includes a conveying component 131 and a sampling component 132 .
[0065] The transport component 131 is used for sample transport.
[0066] The sampling assembly 132 is used to collect samples after completing the liquid flushing operation of its liquid circuit.
[0067] The detection module 11 is used to perform sample detection after completing the liquid flushing operation of its liquid circuit.
[0068] In response to the detection module 11 being in a dormant state and receiving a sample detection instruction, the detection module 11 is synchronously controlled to execute an exit-dormant action and the injection module 13 is controlled to execute an injection action. After the exit-dormant action is completed, the detection module 11 is controlled to perform sample detection, including:
[0069] In response to the detection module 11 being in a dormant state and receiving a sample detection instruction, the sampling component 132 and the detection module 11 are controlled to perform a liquid flushing operation of their liquid circuits. Before the liquid flushing operation is completed, the delivery component 131 is controlled to deliver the sample to the corresponding sampling position. After the liquid flushing operation of the sampling component 132 is completed, the sampling component 132 is controlled to collect the sample at the sampling position.
[0070] After the exit from sleep mode is completed, the control detection module 11 performs sample detection, including:
[0071] After the liquid flushing operation of the detection module 11 is completed, the detection module 11 is controlled to detect the collected samples.
[0072] Specifically, as described in the above embodiments, the detection module 11 needs to be filled with corresponding liquid in order to exit the sleep state and enter the running state for normal operation. The liquid flushing operation can be performed on the relevant liquid circuits of the corresponding components to achieve the liquid flushing inside the components.
[0073] Since the conveying component 131 is usually a purely mechanical structure and is used to transport test tubes or test tube racks containing samples, when the detection module 11 exits the sleep state, the conveying component 131 can be controlled to perform its sample conveying operation. After all components in the detection module 11 exit the sleep state, the sampling component 132 can be controlled to perform the corresponding collection operation, and then the detection module 11 can be controlled to perform the corresponding detection operation.
[0074] Based on the above method, the efficiency of sample detection can be improved as much as possible.
[0075] Optionally, the liquid flushing operation includes a liquid filling operation, or the liquid flushing operation includes a cleaning operation and a liquid filling operation.
[0076] The cleaning operation is used to flush the corresponding liquid circuit with liquid to achieve cleaning.
[0077] The filling operation is used to fill the corresponding pipeline with liquid to achieve liquid filling.
[0078] Specifically, if the sleep time is less than the preset sleep time threshold, the liquid flushing operation may include only the liquid filling operation, and if the sleep time is not less than the preset sleep time threshold, the liquid flushing operation may include the cleaning operation and the liquid filling operation.
[0079] In one example, the sample detection device 10 may be Figure 2 As shown, the first pipette needle 1321 and the second pipette needle 1322 described in the previous embodiment are also included. If the detection module 11 is to be controlled to exit the sleep state, the first pipette needle 1321 can be controlled to suck the remaining liquid in the corresponding reaction cup, and even the reaction cup can be supplemented with diluent more than twice, so that the first pipette needle 1321 can suck the diluent more than twice to flush its internal pipeline. The second pipette needle 1322 and the detection module 11 can also be controlled to suck the diluent more than once to flush their internal pipelines. At this point, the above-mentioned cleaning operation is completed.
[0080] After the cleaning operation is completed, the filling operation can be carried out.
[0081] The filling operation is to continue to control the corresponding components to absorb the diluent to fill their pipelines and prepare for sample testing.
[0082] Based on the above method, the preparation efficiency of sample detection can be improved when the sleep time is short, and the reliability of sample detection can be improved when the sleep time is long.
[0083] In one embodiment, the control module 12 is further configured to:
[0084] In response to the detection module 11 being in the sleep state and receiving the maintenance instruction, the detection module 11 is controlled to execute an exit-sleep action, and after the exit-sleep action is completed, the detection module 11 is controlled to perform a maintenance operation corresponding to the maintenance instruction.
[0085] Specifically, when the detection module 11 needs to be maintained, due to the wide variety of maintenance operations, it may be necessary to perform the inspection when the corresponding component to be maintained is in operation. Therefore, it is necessary to let the detection module 11 completely exit the sleep state before performing the maintenance operation corresponding to the maintenance instruction to ensure the smooth progress of the maintenance operation. Therefore, based on the above method, the reliability of the sample detection device 10 can be improved.
[0086] In one embodiment, the control module 12 is further configured to:
[0087] In response to not receiving any instruction within a first preset time after the detection module 11 is turned on or after detection, a prompt message is output, and based on the user's feedback information on the prompt message, the detection module 11 is put into sleep mode.
[0088] Specifically, the prompt information can be a pop-up message displayed by the sample detection device 10 on its display module. When the detection module 11 has not received any instructions and has not performed any operation within the first preset time period, it can be determined that the detection module 11 is in an idle state, so the prompt information can be output to ask the user whether to let the sample detection device 10 enter the sleep state immediately.
[0089] The sample detection device 10 can be controlled to sleep based on the user's instructions, thereby improving the flexibility of the sample detection device.
[0090] Optionally, based on the user's feedback information on the prompt information, the sleep control of the detection module 11 includes:
[0091] In response to the feedback information being a positive instruction input by the user, or the feedback information being no response from the user, the detection module 11 is controlled to enter a dormant state.
[0092] In response to the feedback information being a negative instruction input by the user, the prompt information is re-output at an interval of a second preset time length, and in response to the output times of the prompt information being greater than a preset times threshold, the control detection module 11 executes a sleep entry action to put it into a sleep state.
[0093] Specifically, the preset number threshold may be two times, three times, ten times or other times, which is not limited here.
[0094] After outputting the prompt information, if the user inputs an affirmative instruction or no instruction, the detection module 11 can be immediately controlled to enter a sleep state. If the user inputs a negative instruction, the prompt information will be output in sequence after a second preset time interval. However, if the number of times the prompt information is output exceeds the preset number threshold, the detection module 11 will be directly controlled to enter a sleep state, thereby forcing the module to sleep.
[0095] Based on the above manner, the possibility of wasting resources of the detection module 11 can be further reduced, thereby reducing the use cost of the sample detection device 10 .
[0096] In one embodiment, the sample injection module 13 includes: a conveying component 131, which is used for sample conveying; and a sampling component 132, which is used for sample collection.
[0097] The synchronous control detection module 11 executes the exit from sleep mode action and the control injection module 13 executes the injection action, including:
[0098] The detection module 11 is controlled to execute the exit from sleep mode, and at the same time, the conveying assembly 131 is controlled to convey the sample tube or the sample rack carrying the sample tube to the sample suction position.
[0099] After the exit from sleep mode is completed, the control detection module 11 performs sample detection, including:
[0100] After the exiting sleep action is completed, the sampling component is controlled to collect samples from the sample tube at the sample suction position, and the collected samples are transported to the detection module 11, and the detection module 11 is controlled to perform sample detection on the samples.
[0101] or,
[0102] The sampling assembly includes a pipette needle, which is used to collect samples.
[0103] The synchronous control detection module 11 executes the exit from sleep mode action and the control injection module 13 executes the injection action, including:
[0104] The detection module 11 is controlled to execute the exit from sleep mode, and at the same time, the transport component 131 is controlled to transport the sample tube or the sample rack carrying the sample tube to the sample suction position.
[0105] The aspiration needle in the sampling component is controlled to collect samples from the sample tube at the sampling position, so as to aspirate the sample into the aspiration needle in the sampling component for standby use.
[0106] After the exit from sleep mode is completed, the control detection module 11 performs sample detection, including:
[0107] After the exiting sleep action is completed, the aspiration needle in the sampling assembly is controlled to transport the collected sample to the detection module 11, and the detection module 11 is controlled to perform sample detection on the sample.
[0108] Specifically, in the first example, when the detection module 11 is in a dormant state and the control module 12 receives a sample detection instruction, the sample injection module 13 can be controlled to start transporting the sample tube or the sample rack carrying the sample tube to the sample suction position while the detection module 11 is controlled to start exiting the dormant state. Since the time required for the sample injection module 13 to exit the dormant state is extremely short, even close to 0, the sample detection device 10 can start executing operations related to sample detection before the detection module 11 has completely exited the dormant state, thereby improving the overall efficiency of sample detection. Subsequently, when the detection module 11 completely exits the dormant state, the sample injection module 13 is controlled to collect samples and the detection module 11 is controlled to perform sample detection.
[0109] In the second example, when the detection module 11 is in a dormant state and the control module 12 receives a sample detection instruction, the sample injection module 13 can be controlled to start transporting the sample tube or the sample rack carrying the sample tube to the sample suction position while the detection module 11 is controlled to start exiting the dormant state, and the sample injection module 13 can be controlled to collect the sample at the sample suction position. Since the time required for the sample injection module 13 to exit the dormant state is extremely short, even close to 0, the sample detection device 10 can start to perform operations related to sample detection before the detection module 11 has completely exited the dormant state, thereby improving the overall efficiency of sample detection. Subsequently, the detection module 11 is controlled to perform sample detection when the detection module 11 completely exits the dormant state.
[0110] Based on the above method, the sample can be transported before the detection module 11 exits the sleep state, thereby increasing the waiting time for the sample detection by the detection module 11 after the subsequent exit from the sleep state is completed, thereby improving the efficiency of the sample detection.
[0111] Optionally, the liquid aspiration needle includes a first liquid aspiration needle 1321 and a second liquid aspiration needle 1322, the first liquid aspiration needle 1321 is only used for liquid aspiration, and the second liquid aspiration needle 1322 can be used for liquid aspiration and discharge.
[0112] The synchronous control detection module 11 executes the exit from sleep mode action and the control injection module 13 executes the injection action, including:
[0113] In response to the detection module 11 being in the dormant state for a time period greater than a preset time threshold, the detection module 11 is controlled to exit the dormant state, and the transport component 131 is controlled to transport the sample tube or the sample rack carrying the sample tube to the sample aspiration position. The first aspiration needle 1321 and the second aspiration needle 1322 are controlled to aspirate the diluent for cleaning.
[0114] In response to the detection module 11 being in the dormant state for a time period not exceeding the preset time period threshold, the detection module 11 is controlled to exit the dormant state, and the conveying component 131 is controlled to convey the sample tube or the sample rack carrying the sample tube to the sample aspiration position. The aspiration needle in the sampling component is controlled to collect samples from the sample tube at the sample aspiration position, so as to aspirate the sample into the aspiration needle in the sampling component for standby use.
[0115] After the exit from sleep mode is completed, the control detection module 11 performs sample detection, including:
[0116] In response to the time length during which the detection module 11 is in the sleep state being greater than a preset time length threshold, then: after the exit from sleep mode is completed and the first aspiration needle 1321 and the second aspiration needle 1322 are cleaned, the first aspiration needle 1321 and / or the second aspiration needle 1322 are controlled to collect samples from the sample tube at the sample aspiration position, and the collected samples are transported to the detection module 11, and the detection module 11 is controlled to perform sample detection on the samples.
[0117] In response to the fact that the duration of the detection module 11 being in the sleep state is not greater than the preset duration threshold, then: after the exit from sleep mode is completed, the first aspiration needle 1321 and / or the second aspiration needle 1322 are controlled to transport the collected sample to the detection module 11, and the detection module 11 is controlled to perform sample detection on the sample.
[0118] Specifically, if the detection module 11 is in the sleep state for a period longer than a preset time threshold, after controlling the conveying component 131 to convey the sample tube or the sample rack carrying the sample tube to the sample suction position, the first aspiration needle 1321 and the second aspiration needle 1322 are controlled to aspirate the diluent to clean the inside thereof, and then the detection module 11 is controlled to perform sample detection after the detection module 11 exits the sleep state, thereby reducing the possibility of internal accumulation of pollutants affecting the sample detection results due to excessive sleep time.
[0119] If the duration that the detection module 11 is in the dormant state is not greater than the preset duration threshold, it is not necessary to perform the above-mentioned cleaning after controlling the conveying component 131 to convey the sample tube or the sample rack carrying the sample tube to the sample aspiration position. Instead, the sample can be aspirated into the aspiration needle for standby use. Subsequently, after the detection module 11 exits the dormant state, the detection module 11 is controlled to perform sample detection. Since the dormant time is short, the amount of contaminants in the aspiration needle is extremely small or approximately equal to 0, so the efficiency of sample detection can be maximized while ensuring the reliability of the test results.
[0120] Based on the above method, it is possible to determine whether the detection module 11 has been in sleep mode for too long based on whether the duration of the last sleep state is greater than a preset duration threshold, and perform different actions based on different determination results to improve the reliability and / or efficiency of sample detection in corresponding situations.
[0121] The present application also proposes a control method for a sample detection device, which is applied to the sample detection device 10 described in any of the above embodiments. The sample detection device 10 includes a detection module 11 and a control module 12. The detection module 11 is used to detect the sample.
[0122] Control methods include:
[0123] In response to the detection module 11 being in the sleep state and receiving the sample detection instruction, the detection module 11 is controlled to exit the sleep state, and before the detection module 11 exits the sleep state, the detection module 11 is controlled to perform sample detection.
[0124] Specifically, the control method may also include other steps that can be implemented by the aforementioned control module 12, which are not limited here.
[0125] The sample detection device may also be a sample analyzer or other devices, which are not limited here.
[0126] Different from the prior art, in the technical solution of the present application, when the sample detection device is in a sleep state, if a sample detection instruction input by the user is received, the detection module of the sample detection device is controlled to execute an exit from sleep mode. Since the injection module can be awakened immediately and operate normally after receiving the sample detection instruction, the injection module can be controlled to start part of the sample detection operation before the detection module is exiting the sleep state but has not completely exited the sleep state, thereby avoiding the situation where the sample detection can only be performed after the detection module completely exits the sleep state, thereby improving the efficiency of sample detection.
[0127] In the description of the present application, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example", or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, without contradicting each other.
[0128] In addition, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include at least one of the features. In the description of this application, the meaning of "plurality" is at least two, such as two, three, etc., unless otherwise clearly and specifically defined.
[0129] Any process or method description in a flowchart or otherwise described herein may be understood to represent a module, segment or portion of code that includes one or more executable instructions for implementing the steps of a specific logical function or process, and the scope of the preferred embodiments of the present application includes alternative implementations in which functions may not be performed in the order shown or discussed, including performing functions in a substantially simultaneous manner or in the reverse order depending on the functions involved, which should be understood by technicians in the technical field to which the embodiments of the present application belong.
[0130] The logic and / or steps represented in the flowchart or otherwise described herein, for example, can be considered as an ordered list of executable instructions for implementing the logical functions, and can be embodied in any computer-readable medium for use by an instruction execution system, device or apparatus (which can be a personal computer, server, network device or other system that can fetch instructions from the instruction execution system, device or apparatus and execute the instructions), or in combination with these instruction execution systems, devices or apparatuses. For the purpose of this specification, "computer-readable medium" can be any device that can contain, store, communicate, propagate or transmit a program for use by an instruction execution system, device or apparatus or in combination with these instruction execution systems, devices or apparatuses. More specific examples of computer-readable media (a non-exhaustive list) include the following: an electrical connection with one or more wires (electronic device), a portable computer disk box (magnetic device), a random access memory (RAM), a read-only memory (ROM), an erasable and programmable read-only memory (EPROM or flash memory), a fiber optic device, and a portable compact disk read-only memory (CDROM). In addition, the computer-readable medium may even be paper or other suitable medium on which the program is printed, since the program may be obtained electronically, for example, by optically scanning the paper or other medium and then editing, interpreting or processing in other suitable ways if necessary, and then stored in a computer memory.
[0131] The above description is only an implementation method of the present application, and does not limit the patent scope of the present application. Any equivalent structure or equivalent process transformation made using the contents of the present application specification and drawings, or directly or indirectly used in other related technical fields, are also included in the patent protection scope of the present application.
Claims
1. A sample detection device, characterized in that: include: Injection module; A detection module, wherein the detection module is used to detect the sample; A control module is connected to the injection module and the detection module respectively, and the control module is used to: In response to the detection module being in a dormant state and receiving a sample detection instruction, synchronously controlling the detection module to execute an exit from dormancy action and controlling the injection module to execute an injection action; After the exiting sleep action is completed, the detection module is controlled to perform sample detection.
2. The sample detection device according to claim 1, characterized in that: The injection module comprises: Conveying components; The first aspiration needle is only used for aspiration of liquid; The control module is also used for: In response to the detection module being about to enter a dormant state, the first aspiration needle is controlled to aspirate diluent, so that the detection module enters a dormant state.
3. The sample detection device according to claim 2, characterized in that: The injection module further comprises a second liquid aspiration needle, which is used for aspirating and discharging liquid; In response to the detection module being about to enter a dormant state, controlling the first aspiration needle to aspirate diluent to enable the detection module to enter a dormant state includes: In response to the detection module entering a dormant state, the second liquid aspirating needle is controlled to aspirate the diluent and spit it into the reaction cup; Controlling the conveying component to convey the reaction cup to a sampling position; The first liquid aspiration needle is controlled to aspirate the diluent in the reaction cup, so that the detection module enters a dormant state.
4. The sample detection device according to claim 3, characterized in that: The controlling the first aspiration needle to aspirate the diluent in the reaction cup to enable the detection module to enter a dormant state includes: The first pipetting needle is controlled to absorb part of the diluent in the reaction cup, and the needle head of the first pipetting needle is controlled to be immersed in the remaining diluent in the reaction cup, so that the detection module enters a dormant state.
5. The sample detection device according to claim 4, characterized in that: The number of the first liquid aspiration needles is more than two, and the more than two first liquid aspiration needles include magnetic separation liquid aspiration needles and / or waste liquid needles; The controlling the first pipetting needle to absorb part of the diluent in the reaction cup and controlling the needle tip of the first pipetting needle to immerse in the remaining diluent in the reaction cup, so that the detection module enters a dormant state, includes: Each of the first aspiration needles is controlled to absorb part of the diluent in the corresponding reaction cup, and the needle head of each of the first aspiration needles is controlled to be immersed in the remaining diluent in the corresponding reaction cup, so that the detection module enters a dormant state.
6. The sample detection device according to any one of claims 1 to 5, characterized in that: The injection module comprises: A conveying component, wherein the conveying component is used for sample conveying; A sampling assembly, the sampling assembly is used to collect samples after completing the liquid flushing operation of its liquid circuit; The detection module is used to perform sample detection after completing the liquid flushing operation of its liquid circuit; In response to the detection module being in a dormant state and receiving a sample detection instruction, synchronously controlling the detection module to execute an exit from dormancy action and controlling the injection module to execute an injection action, including: In response to the detection module being in a dormant state and receiving a sample detection instruction, the sampling component and the detection module are controlled to perform a liquid flushing operation on their liquid circuits; before the liquid flushing operation is completed, the delivery component is controlled to deliver the sample to the corresponding sampling position; after the liquid flushing operation of the sampling component is completed, the sampling component is controlled to collect the sample from the sampling position; After the exiting sleep action is completed, controlling the detection module to perform sample detection includes: After the liquid flushing operation of the detection module is completed, the detection module is controlled to detect the collected samples.
7. The sample detection device according to any one of claims 1 to 5, characterized in that: The sample injection module comprises: a conveying component, which is used for sample conveying; a sampling component, which is used for sample collection; The synchronously controlling the detection module to execute the exit from sleep mode and the controlling the injection module to execute the injection mode comprises: Controlling the detection module to execute an exit from sleep mode, and simultaneously controlling the transport component to transport the sample tube or the sample rack carrying the sample tube to the sample suction position; After the exiting sleep action is completed, controlling the detection module to perform sample detection includes: After the exit from sleep mode is completed, the sampling assembly is controlled to collect samples from the sample tube at the sample suction position, and the collected samples are transported to the detection module, and the detection module is controlled to perform sample detection on the samples; or, The sampling assembly comprises a liquid aspiration needle, and the liquid aspiration needle is used to collect samples; The synchronously controlling the detection module to execute the exit from sleep mode and the controlling the injection module to execute the injection mode comprises: Controlling the detection module to execute an exit from sleep mode, and simultaneously controlling the transport component to transport the sample tube or the sample rack carrying the sample tube to the sample suction position; Controlling the aspiration needle in the sampling assembly to collect samples from the sample tube at the sampling position, so as to aspirate the sample into the aspiration needle in the sampling assembly for standby use; After the exiting sleep action is completed, controlling the detection module to perform sample detection includes: After the exiting sleep action is completed, the aspiration needle in the sampling assembly is controlled to transport the collected sample to the detection module, and the detection module is controlled to perform sample detection on the sample.
8. The sample detection device according to claim 7, characterized in that: The liquid aspiration needle comprises: a first liquid aspiration needle, which is only used for aspiration of liquid; and a second liquid aspiration needle, which is used for aspiration and discharge of liquid; The synchronously controlling the detection module to execute the exit from sleep mode and the controlling the injection module to execute the injection mode comprises: In response to the detection module being in the dormant state for a time period greater than a preset time threshold, the detection module is controlled to exit the dormant state, and the transport component is controlled to transport the sample tube or the sample rack carrying the sample tube to the sample aspiration position; the first aspiration needle and the second aspiration needle are controlled to aspirate diluent for cleaning; In response to the detection module being in the dormant state for a time period not exceeding a preset time period threshold, the detection module is controlled to exit the dormant state, and the transport component is controlled to transport the sample tube or the sample rack carrying the sample tube to the sample aspiration position; the aspiration needle in the injection component is controlled to collect the sample from the sample tube at the sample aspiration position, so as to aspirate the sample into the aspiration needle in the injection component for standby use; After the exiting sleep action is completed, controlling the detection module to perform sample detection includes: In response to the time length of the detection module being in the dormant state being greater than a preset time length threshold, then: after the exit from dormancy action is completed and the first aspiration needle and the second aspiration needle are cleaned, the first aspiration needle and / or the second aspiration needle are controlled to collect samples from the sample tube at the sample aspiration position, and the collected samples are transported to the detection module, and the detection module is controlled to perform sample detection on the samples; In response to the time length that the detection module is in the sleep state is not greater than a preset time length threshold, then: after the exit from sleep mode is completed, the first aspiration needle and / or the second aspiration needle are controlled to transport the collected sample to the detection module, and the detection module is controlled to perform sample detection on the sample.
9. The sample detection device according to any one of claims 1 to 5, characterized in that: The control module is also used for: In response to not receiving any instruction within a first preset time after the detection module is turned on or after detection, outputting a prompt message; In response to the feedback information being a positive instruction input by the user, or the feedback information being no response from the user, controlling the detection module to enter a dormant state; In response to the feedback information being a negative instruction input by the user, the prompt information is re-output at an interval of a second preset time length, and in response to the output number of times of the prompt information being greater than a preset number threshold, the detection module is controlled to enter a dormant state.
10. A control method for a sample detection device, characterized in that: The sample detection device comprises a sample injection module, a detection module and a control module, wherein the detection module is used to detect the sample; The control method comprises: In response to the detection module being in a dormant state and receiving a sample detection instruction, synchronously controlling the detection module to execute an exit from dormancy action and controlling the injection module to execute an injection action; After the exiting sleep action is completed, the detection module is controlled to perform sample detection.