Tumor marker detection kit

Abstract

The invention discloses a tumor marker detection kit, and relates to the field of tumor molecular pathology, the tumor marker detection kit is characterized in that a protective cover is mounted above a mounting box, the protective cover is rotatably mounted on the back surface of the mounting box, a handle is mounted above the protective cover, and the protective cover is rotatably mounted above the protective cover; a rotating gear is mounted in the mounting box, and a meshing sliding mechanism for sliding the reagent fixing frame is mounted on the side surface of the rotating gear. According to the tumor marker detection kit, when a reagent tube needs to be placed or taken, a sliding gear rod is pulled along a mounting box, a rotating gear is driven by sliding of the sliding gear rod to rotate circumferentially, and the rotating gear rotates to drive a transmission gear rod in contact with the other end to move upwards; and the reagent fixing frame and the transmission gear rod are fixedly mounted, so that the reagent fixing frame is driven to move upwards at the same time, and the reagent tube placed in the reagent fixing frame can be taken more simply and conveniently.

Description

Technical Field

[0001] The present invention relates to the technical field of tumor molecular pathology, in particular to a tumor marker detection kit. Background Art

[0002] Tumor markers, also known as tumor markers, refer to substances that characteristically exist in malignant tumor cells, or are abnormally produced by malignant tumor cells, or are produced by the host's response to tumor stimulation, and can reflect the occurrence and development of tumors, and monitor the tumor's response to treatment. Tumor markers exist in the tissues, body fluids and excretions of tumor patients and can be detected by immunological, biological and chemical methods. Tumor marker detection kits are boxes that hold chemical reagents needed to detect tumors.

[0003] Since tumor detection requires a large number of reagents of various types and quantities, and in order to ensure the stability of the reagent kit, the reagents in existing reagent kits are often arranged in multiple rows, which makes it inconvenient to find the reagents when using them. At the same time, due to the dense arrangement and small gaps between the reagent tubes, it is inconvenient to take them out.

[0004] In order to overcome the above defects, the prior art (application number: CN214453014U, Chinese patent with application date of 2021-02-24) discloses a tumor marker detection kit, including a box, an installation space is provided inside the box, a cross partition is installed in the installation space, the top surface of the cross partition is respectively provided with a placement hole and a pressure rod hole, and the bottom of the cross partition is provided with a rectangular hole. The device drives the tilting rod to perform lever work by pressing the pressing rod downward to press the other end upward, and then drives the top rod to move upward, so that the top of the top rod contacts the bottom end of the reagent tube, and lifts the reagent tube upward, so that the reagent tubes in the same row are raised higher than other reagent tubes as a whole, thereby solving the problem that the labels attached to the surface of the reagent tubes in the rear row are blocked by the reagent tubes in the front row and are inconvenient to observe. The device finally drives the reagent tubes to rise by pressing the pressing rod, so that the reagent tubes in the same row are raised as a whole, so that they are not affected by the dense arrangement of the reagent tubes, so that the operator can more easily take out the reagent tubes in the middle.

[0005] Although the existing design can solve the above problems, it is not effective in fixing the shaking caused by placing it in a fixed position, and it is not convenient when taking or placing the reagent box. Most designs require directly reaching into the reagent box for taking and placing operations, which may easily cause spillage or solvent mixing, and the overall bearing capacity of the reagent box needs to be improved. If the fixing strength is not enough, the movement safety will be reduced in the face of human or external impact. Summary of the invention

[0006] The purpose of the present invention is to provide a tumor marker detection kit to solve the problem proposed in the above-mentioned background technology that the fixing effect is not good due to shaking after being placed in a fixed position, and it is not convenient when it is necessary to take or place the kit. Most designs require directly reaching into the inside of the kit to take and place the kit, which is easy to spill or cause solvent mixing, and the overall bearing capacity of the kit needs to be improved. If the fixing strength is not strong enough, the movement safety will be reduced when facing human or external impact.

[0007] To achieve the above-mentioned purpose, the present invention provides the following technical solution: a tumor marker detection kit, comprising a protective cover installed on the top of the installation box, and the protective cover is rotatably installed on the back of the installation box, a handle is installed on the top of the protective cover, and the protective cover is rotatably installed on the top of the protective cover, a rotating gear is installed inside the installation box, and a meshing sliding mechanism for sliding a reagent fixing frame is installed on the side of the rotating gear, the meshing sliding mechanism includes a sliding gear rod, and the sliding gear rod is slidably installed on the side of the installation box, the rotating gear and the sliding gear rod are in contact with each other, and the other end of the rotating gear is in contact with the transmission gear rod, a reagent fixing frame is installed on the side of the transmission gear rod, and a fixed sliding rod is installed on the left side of the reagent fixing frame; A semicircular abutment rod is installed on the lower surface of the protective cover, and an elastic transmission mechanism for fixing the sliding fixing plate is installed on the rotation track of the semicircular abutment rod.

[0008] Furthermore, the elastic transmission mechanism includes a semicircular sliding rod, and the upper surface of the mounting box is installed with an inner mounting groove, the interior of the inner mounting groove is installed with a semicircular sliding rod, the outer surface of the semicircular sliding rod is installed with a second spring, and the outer surface of the semicircular sliding rod is installed with an engaging interference frame.

[0009] Furthermore, the side of the interlocking interference frame contacts the end of the second spring, and the semicircular sliding rod is designed to be semicircular, a sliding fixing plate is installed at the end of the semicircular sliding rod, and the semicircular sliding rod and the second spring as well as the interlocking interference frame and the sliding fixing plate are installed in two groups symmetrically about the center point of the installation box.

[0010] Furthermore, a reagent fixing rack is installed inside the installation box, and a sliding resistance rack is installed on the back of the reagent fixing rack, an interlocking rod is installed inside the sliding resistance rack, and a first spring is installed on the outer surface of the interlocking rod, and a nesting rack is installed on the lower surface of the protective cover, and the nesting rack and the interlocking rod are nested.

[0011] Furthermore, a limit frame is installed on the outer surface of the fixed sliding rod, and the limit frame is fixedly installed on the inner surface of the installation box, a lifting frame is installed inside the installation box, and a reagent fixing frame is installed above the lifting frame, a first deceleration magnet is installed inside the installation box, and a second deceleration magnet is installed on the lower surface of the protective cover.

[0012] Furthermore, the outer surface of the rotating gear contacts the side of the sliding gear rod to form a meshing structure, and the reagent fixing frame and the transmission gear rod are integrally designed, and the outer surface of the rotating gear contacts the side of the transmission gear rod to form a meshing structure.

[0013] Furthermore, the rotating gear is fixedly installed on the side surface of the transmission gear rod and the side surface of the reagent fixing frame to form a transmission structure, and the handle is rotatably installed above the protective cover.

[0014] Furthermore, the inner surface of the limit frame contacts the outer surface of the fixed sliding rod to form a sliding structure, and two groups of lifting frames are installed symmetrically about the center point of the installation box, and the movement direction of the first deceleration magnet corresponds to the position of the second deceleration magnet to play a buffering role.

[0015] Furthermore, the semicircular sliding rod is integrally designed with the sliding fixing plate, and the end of the second spring contacts the side of the engaging abutment frame to form an elastic structure, and the upper surface of the reagent fixing frame contacts the lower surface of the sliding fixing plate to form a sliding structure.

[0016] Furthermore, the nesting frame is nested and installed inside the embedding rod, and the protective cover and the nesting frame are designed as an integral unit, and the inner surface of the sliding contact frame contacts the end of the first spring to form an elastic structure.

[0017] Compared with the prior art, the beneficial effects of the present invention are as follows: when the tumor marker detection kit needs to place or take out a reagent tube, the sliding gear rod is pulled along the installation box, and the sliding of the sliding gear rod drives the rotating gear to rotate in a circle, and the rotation of the rotating gear drives the transmission gear rod in contact with the other end to move upward, and since the reagent fixing frame is fixedly installed with the transmission gear rod, the reagent fixing frame is driven to move upward at the same time, and the reagent tube placed inside the reagent fixing frame can also be taken out more easily; Furthermore, when the reagent fixing frame moves upward, the engaging rod also lifts the nesting frame fixed at the lower end of the protective cover upward. Since the installation box and the protective cover are rotatably installed, the protective cover is opened in a circle. The process of the engaging rod lifting upward compresses the first spring of the external nesting. In order to better cope with the gravity pressure of the protective cover, such a design enhances the overall service life of the reagent kit and better protects the internal reagent tubes. Such a design makes the opening of the protective cover more convenient and the use of the overall reagent kit faster. Moreover, the handle on the protective cover can be used for auxiliary movement while opening, so as to better complete the opening of the reagent kit. Furthermore, when the protective cover is closed, the one-piece semicircular interference rod also rotates downward in a circular motion, and after entering the installation inner groove, the semicircular sliding rod is pushed forward along the inside of the interlocking interference frame, and the semicircular sliding rod drives the sliding fixing plate fixed at the front end to slide at the same time, and the sliding fixing plate contacts the upper end of the reagent fixing frame, fixing the reagent fixing frame between the sliding fixing plate and the lifting frame. Such a design enables better bearing capacity in the event of shaking or human impact, and the internal reagent tube will not swing or the reagent will not fuse due to looseness. BRIEF DESCRIPTION OF THE DRAWINGS

[0018] Figure 1 This is a schematic diagram of the three-dimensional structure of the sliding gear rod of the present invention; Figure 2 This is a schematic diagram of the three-dimensional structure of the fixed sliding rod of the present invention; Figure 3 It is a schematic diagram of the three-dimensional structure of the semicircular interference rod of the present invention; Figure 4 It is a schematic diagram of the three-dimensional structure of the nested frame of the present invention; Figure 5 This is a schematic diagram of the three-dimensional structure of the reagent fixing frame of the present invention; Figure 6 It is a schematic diagram of the three-dimensional structure of the lifting frame of the present invention; Figure 7 It is a schematic diagram of the three-dimensional structure of the sliding contact frame of the present invention; Figure 8 It is a schematic diagram of the three-dimensional structure of the first spring of the present invention; Fig. 9 It is a schematic diagram of the three-dimensional structure of the reagent tube of the present invention.

[0019] In the figure: 1. Installation box; 2. Protection cover; 3. Rotating gear; 4. Sliding gear rod; 5. Handle; 6. Semicircular interference rod; 7. Nesting frame; 8. Limiting frame; 9. Fixed sliding rod; 10. Reagent fixing frame; 11. Reagent tube; 12. Installation inner groove; 13. Mosaic rod; 14. Lifting frame; 15. Sliding interference frame; 16. First spring; 17. Semicircular sliding rod; 18. Second spring; 19. Mosaic interference frame; 20. Sliding fixed plate; 21. Transmission gear rod; 22. First deceleration magnet; 23. Second deceleration magnet. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Example 1: Please refer to Figure 1-6 The present invention provides the following technical solution: a tumor marker detection kit, comprising an installation box 1, a protective cover 2 and a second deceleration magnet 23.

[0022] A protective cover 2 is installed above the installation box 1, and the protective cover 2 is rotatably installed on the back of the installation box 1. A handle 5 is installed above the protective cover 2, and the protective cover 2 is rotatably installed above the protective cover 2. A rotating gear 3 is installed inside the installation box 1, and a meshing sliding mechanism for sliding the reagent fixing frame 10 is installed on the side of the rotating gear 3. The meshing sliding mechanism includes a sliding gear rod 4, and the sliding gear rod 4 is slidably installed on the side of the installation box 1. The rotating gear 3 and the sliding gear rod 4 are in contact with each other, and the other end of the rotating gear 3 is in contact with the transmission gear rod 21. The reagent fixing frame 10 is installed on the side of the transmission gear rod 21, and the left side of the reagent fixing frame 10 is installed with a fixed sliding rod 9; A semicircular abutment rod 6 is installed on the lower surface of the protection cover 2 , and an elastic transmission mechanism for fixing the sliding fixing plate 20 is installed on the rotation track of the semicircular abutment rod 6 .

[0023] like Figure 1 , Figure 2 , Figure 4 , Figure 5 , Figure 8The technical solution shown in the figure, in order to solve the problem that the test tube is not convenient to take and is easy to spill, discloses: the outer surface of the fixed sliding rod 9 is installed with a limit frame 8, and the limit frame 8 is fixedly installed on the inner surface of the installation box 1, the installation box 1 is installed with a lifting frame 14, and the reagent fixing frame 10 is installed above the lifting frame 14, the installation box 1 is installed with a first deceleration magnet 22, and the lower surface of the protective cover 2 is installed with a second deceleration magnet 23, the outer surface of the rotating gear 3 is in contact with the side of the sliding gear rod 4 to form a meshing structure, and the reagent fixing frame 10 is connected with the transmission frame 14. The gear rod 21 is an integrated design, and the outer surface of the rotating gear 3 contacts the side of the transmission gear rod 21 to form an engaging structure. The rotating gear 3 is fixedly installed on the side of the reagent fixing rack 10 through the side surface of the transmission gear rod 21 to form a transmission structure, and the handle 5 is rotatably installed above the protective cover 2. The inner surface of the limit rack 8 contacts the outer surface of the fixed sliding rod 9 to form a sliding structure, and the lifting rack 14 is symmetrically installed in two groups about the center point of the installation box 1, and the movement direction of the first deceleration magnet 22 corresponds to the position of the second deceleration magnet 23 to play a buffering role.

[0024] When it is necessary to take out the reagent tube 11, the sliding gear rod 4 is pulled downward along the right side of the installation box 1. The downward sliding of the sliding gear rod 4 drives the rotating gear 3 installed inside the installation box 1 on the left side to rotate in a circle. While the rotating gear 3 rotates along the inside of the installation box 1, the transmission gear rod 21 contacted by the other end surface of the rotating gear 3 generates a meshing motion again. The transmission gear rod 21 moves upward due to the meshing motion. Since the reagent fixing frame 10 and the transmission gear rod 21 are fixedly connected, the reagent fixing frame 10 moves synchronously with the movement of the transmission gear rod 21. The upward movement of the reagent fixing frame 10 causes the fixed sliding rod 9 fixed on the left side to move upward along the inside of the limiting frame 8 at the same time. The sliding ensures the stability of the movement. The movement of the reagent fixing rack 10 causes the bottom surface of the reagent fixing rack 10 to break away from the contact with the lifting rack 14. As the reagent fixing rack 10 moves upward, the sliding resistance rack 15 fixed on the back of the reagent fixing rack 10 moves upward at the same time, and the interlocking rod 13 nested inside the sliding resistance rack 15 drives the nesting rack 7 nested inside to perform transmission movement. Since the nesting rack 7 is fixedly installed on the lower surface of the protective cover 2, the protective cover 2 is driven to rotate and open along the top of the installation box 1. During the transmission process, the first spring 16 nested on the outer surface of the interlocking rod 13 is squeezed under the constraint of the inside of the sliding resistance rack 15 due to the gravity of the protective cover 2 to achieve a buffering effect.

[0025] like Figure 3 , Figure 7 , Figure 8 , Fig. 9The technical solution shown, in order to solve the problem of insufficient protection design for test tubes when the detection kit is shaken or the like, discloses: the elastic transmission mechanism includes a semicircular sliding rod 17, and the upper surface of the installation box 1 is installed with an installation inner groove 12, the interior of the installation inner groove 12 is installed with a semicircular sliding rod 17, the outer surface of the semicircular sliding rod 17 is installed with a second spring 18, and the outer surface of the semicircular sliding rod 17 is installed with an interlocking abutment frame 19, the side surface of the interlocking abutment frame 19 is in contact with the end of the second spring 18, and the semicircular sliding rod 17 is semicircular in design, and a sliding fixing plate 20 is installed at the end of the semicircular sliding rod 17, and the semicircular sliding rod 17 and the second spring 18 as well as the interlocking abutment frame 19 and the sliding fixing plate 20 are installed in two groups symmetrically about the center point of the installation box 1, and the installation box 1 A reagent fixing rack 10 is installed inside, and a sliding resistance rack 15 is installed on the back of the reagent fixing rack 10, a fitting rod 13 is installed inside the sliding resistance rack 15, and a first spring 16 is installed on the outer surface of the fitting rod 13, a nesting rack 7 is installed on the lower surface of the protective cover 2, and the nesting rack 7 and the fitting rod 13 are nested, the semicircular sliding rod 17 and the sliding fixing plate 20 are designed as an integral whole, and the fitting end of the second spring 18 contacts the side of the fitting resistance rack 19 to form an elastic structure, and the upper surface of the reagent fixing rack 10 contacts the lower surface of the sliding fixing plate 20 to form a sliding structure, the nesting rack 7 is nested inside the fitting rod 13, and the protective cover 2 and the nesting rack 7 are designed as an integral whole, and the inner surface of the sliding resistance rack 15 contacts the end of the first spring 16 to form an elastic structure.

[0026] After completing the work of taking out the reagent tube 11, use the reverse direction to rotate the rotating gear 3 again or use the handle 5 to assist in closing the protective cover 2. While the protective cover 2 is rotating and closing along the upper end of the installation box 1, the semicircular resistance rod 6 fixedly installed on the lower surface of the protective cover 2 also moves at the same time. When the lower surface of the protective cover 2 is about to completely overlap with the upper end opening of the installation box 1, the second deceleration magnet 23 fixedly installed on the lower surface of the protective cover 2 corresponds to the position of the first deceleration magnet 22 fixed inside the installation box 1, and they generate mutual repulsion when they are about to contact, making the closing process of the protective cover 2 more stable, and the protective cover 2 will not fall on the upper end of the installation box 1 due to hand slippage, causing the entire test kit to shake. At the same time, it also ensures that the reagent tube 11 inside the installation box 1 is safer and will not be affected. As the protective cover 2 completely overlaps with the upper end of the installation box 1, the semicircular resistance rod 6 fixed at the lower end of the protective cover 2 gradually enters the upper surface of the installation box 1 The surface is inside the installation inner groove 12 opened at the corresponding position, and the semicircular resistance rod 6 continues to move downward. During the movement, the semicircular resistance rod 6 contacts the semicircular sliding rod 17. Since the front ends of the semicircular sliding rod 17 and the semicircular resistance rod 6 are all semicircular in design, the semicircular resistance rod 6 pushes the semicircular sliding rod 17 forward along the embedded resistance frame 19 installed outside the semicircular sliding rod 17. When the semicircular sliding rod 17 slides along the embedded resistance frame 19, the second spring 18 embedded outside the semicircular sliding rod 17 is squeezed inward by the semicircular sliding rod 17 due to the limit constraint of the embedded resistance frame 19. The forward sliding of the semicircular sliding rod 17 drives the sliding fixing plate 20 with an integrated design at the front end to move synchronously, and the sliding fixing plate 20 slides against the upper end of the reagent fixing frame 10, fixing the reagent fixing frame 10 between the lifting frame 14 and the sliding fixing plate 20, thereby ensuring the installation stability of the reagent tube 11.

[0027] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "connected" and "connection" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0028] Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments, or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A tumor marker detection kit, comprising an installation box (1), a protective cover (2) and a negative pole magnet (23); Features: A protective cover (2) is installed above the installation box (1), and the protective cover (2) is rotatably installed on the back of the installation box (1). A handle (5) is installed above the protective cover (2), and the protective cover (2) is rotatably installed above the protective cover (2). A rotating gear (3) is installed inside the installation box (1), and a meshing sliding mechanism for sliding a reagent fixing frame (10) is installed on the side of the rotating gear (3). The meshing sliding mechanism includes a sliding gear rod (4), and the sliding gear rod (4) is slidably installed on the side of the installation box (1). The rotating gear (3) and the sliding gear rod (4) are in contact with each other, and the other end of the rotating gear (3) is in contact with a transmission gear rod (21). A reagent fixing frame (10) is installed on the side of the transmission gear rod (21), and a fixed sliding rod (9) is installed on the left side of the reagent fixing frame (10); A semicircular abutment rod (6) is installed on the lower surface of the protective cover (2), and an elastic transmission mechanism for fixing the sliding fixing plate (20) is installed on the rotation track of the semicircular abutment rod (6).

2. The tumor marker detection kit according to claim 1, characterized in that: The elastic transmission mechanism comprises a semicircular sliding rod (17), and an installation inner groove (12) is installed on the upper surface of the installation box (1), the semicircular sliding rod (17) is installed inside the installation inner groove (12), a second spring (18) is installed on the outer surface of the semicircular sliding rod (17), and an engaging abutment frame (19) is installed on the outer surface of the semicircular sliding rod (17).

3. The tumor marker detection kit according to claim 2, characterized in that: The side surface of the interlocking abutment frame (19) contacts the end of the second spring (18), and the semicircular sliding rod (17) is of semicircular design. A sliding fixing plate (20) is installed at the end of the semicircular sliding rod (17). The semicircular sliding rod (17) and the second spring (18) as well as the interlocking abutment frame (19) and the sliding fixing plate (20) are installed in two groups symmetrically about the center point of the installation box (1).

4. The tumor marker detection kit according to claim 3, characterized in that: A reagent fixing frame (10) is installed inside the installation box (1), and a sliding abutment frame (15) is installed on the back of the reagent fixing frame (10). A fitting rod (13) is installed inside the sliding abutment frame (15), and a first spring (16) is installed on the outer surface of the fitting rod (13). A nesting frame (7) is installed on the lower surface of the protective cover (2), and the nesting frame (7) and the fitting rod (13) are nested.

5. The tumor marker detection kit according to claim 1, characterized in that: A limiting frame (8) is installed on the outer surface of the fixed sliding rod (9), and the limiting frame (8) is fixedly installed on the inner surface of the installation box (1). A lifting frame (14) is installed inside the installation box (1), and a reagent fixing frame (10) is installed above the lifting frame (14). A first deceleration magnet (22) is installed inside the installation box (1), and a second deceleration magnet (23) is installed on the lower surface of the protective cover (2).

6. The tumor marker detection kit according to claim 1, characterized in that: The outer surface of the rotating gear (3) contacts the side of the sliding gear rod (4) to form a meshing structure, and the reagent fixing frame (10) and the transmission gear rod (21) are integrally designed, and the outer surface of the rotating gear (3) contacts the side of the transmission gear rod (21) to form a meshing structure.

7. The tumor marker detection kit according to claim 1, characterized in that: The rotating gear (3) is fixedly mounted on the side surface of the transmission gear rod (21) and the side surface of the reagent fixing frame (10) to form a transmission structure, and the handle (5) is rotatably mounted above the protective cover (2).

8. The tumor marker detection kit according to claim 5, characterized in that: The inner surface of the limit frame (8) contacts the outer surface of the fixed sliding rod (9) to form a sliding structure, and two groups of lifting frames (14) are installed symmetrically about the center point of the installation box (1), and the movement direction of the first deceleration magnet (22) and the position of the second deceleration magnet (23) correspond to each other to play a buffering role.

9. The tumor marker detection kit according to claim 3, characterized in that: The semicircular sliding rod (17) and the sliding fixing plate (20) are of an integral design, and the end of the second spring (18) contacts the side surface of the engaging abutment frame (19) to form an elastic structure, and the upper surface of the reagent fixing frame (10) contacts the lower surface of the sliding fixing plate (20) to form a sliding structure.

10. The tumor marker detection kit according to claim 4, characterized in that: The nesting frame (7) is nested and installed inside the embedding rod (13), and the protective cover (2) and the nesting frame (7) are designed as an integral unit, and the inner surface of the sliding contact frame (15) contacts the end of the first spring (16) to form an elastic structure.

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