A device and method for adding raw materials of levofloxacin hydrochloride at a fixed time and in a fixed quantity

By designing a timed and quantitative addition equipment for preparation of levofloxacin hydrochloride, the problems of cumbersome and high cost in the prior art are solved, and efficient, automated timed and quantitative addition of raw materials are achieved, thus reducing labor and maintenance costs.

CN119750241APending Publication Date: 2025-04-04HENAN KANGDA PHARMA
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Patent Information

Application Number
CN202411956916.4
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2024-12-29
Publication Date
2025-04-04

AI Technical Summary

Technical Problem

In the existing levofloxacin hydrochloride synthesis process, the steps of the raw material addition device are cumbersome when quantitative addition are performed, which increases the workload and labor costs of staff, and it is impossible to quickly adjust the proportion of levofloxaccarboxylic acid and N-methylpiperazine. The timing device of electronic structure increases the equipment cost and maintenance costs.

Method used

A timed and quantitative addition equipment for preparation of levofloxacin hydrochloride is designed, including conveying components, support components, storage frames, cutouts, linkage closure components and reset quantitative components. Through the synergistic effect of these components, the timing and quantitative addition of raw materials and automatic unloading are achieved.

Benefits of technology

The raw material addition process is simplified, the operating steps and labor costs of staff are reduced, and the raw material allocation is achieved quickly, the equipment and maintenance costs are reduced, and the production efficiency and product quality are improved.

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Abstract

The present invention relates to the technical field of chemical equipment, specifically to a timed quantitative addition device and method for preparing levofloxacin hydrochloride raw materials, comprising a conveying component, both ends of the upper surface of the conveying component are fixedly connected with a supporting component, the tops of the two supporting components are fixedly connected with a material storage frame, the bottoms of the two material storage frames are fixedly connected with a feeding port, and the two sides of the feeding port are opened as a through-port structure. The timed quantitative addition device and method for preparing levofloxacin hydrochloride raw materials help the raw materials to be automatically unloaded through the tilting component in the supporting component, and the linkage closing component sliding in the feeding port automatically closes the raw materials after reaching a certain weight, and through the timing device, after the previous raw material is unloaded, the timing component is controlled by the anti-rotation sleeve rod to rotate in a linkage manner, and the next raw material is driven to be unloaded after the timing time is reached, so as to ensure the catalytic effect of the raw materials.
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Description

Technical Field

[0001] The invention relates to the technical field of chemical equipment, in particular to equipment and a method for adding raw materials for preparing levofloxacin hydrochloride at a fixed time and fixed quantity. Background Art

[0002] Levofloxacin hydrochloride is the levorotatory form of ofloxacin, and its antibacterial activity is about twice that of ofloxacin. Its main mechanism of action is to inhibit the activity of bacterial DNA gyrase (bacterial topoisomerase II) and hinder bacterial DNA replication.

[0003] The levofloxacin hydrochloride synthesis process in the prior art comprises the following steps: condensing levofloxacin with N-methylpiperazine under the action of a catalyst to generate levofloxacin, then evaporating the solvent, crystallizing in a crystallization solvent and drying to obtain a levofloxacin dry product, and finally salifying levofloxacin with hydrochloric acid and crystallizing multiple times with ethanol to obtain levofloxacin hydrochloride. In the synthesis process, corresponding materials need to be added in sequence. When the quality of the subsequent finished product needs to be guaranteed, the first step of synthesizing levofloxacin is very important. When the existing raw material adding device is quantitatively added, the raw material needs to be first loaded into a weighing frame and then weighed and poured. The steps are complicated and the workload of the staff is increased. The labor cost is high. In the process of continuously adding raw materials, it is impossible to quickly adjust according to the ratio of levofloxacin and N-methylpiperazine. The timing device of the electronic structure increases the equipment cost. Professional equipment personnel are also required to perform regular maintenance to avoid errors, which further increases the labor cost and the maintenance cost is also high.

[0004] In view of this, we propose a device and method for timely and quantitative addition of raw materials for the preparation of levofloxacin hydrochloride. Summary of the invention

[0005] The object of the present invention is to provide a timed and quantitative addition device and method for preparing raw materials of levofloxacin hydrochloride, so as to solve the problem that the existing raw material adding device proposed in the above background technology needs to be loaded into a weighing frame and then weighed and poured when performing quantitative addition, which has complicated steps and increases the workload of staff, and has high labor costs. In the process of continuously adding raw materials, it is impossible to make rapid adjustments according to the ratio of levofloxacin carboxylic acid and N-methylpiperazine, and the timing device of the electronic structure increases the equipment cost, and professional equipment personnel are required to perform regular maintenance to avoid errors, which further increases the labor cost and the maintenance cost is also high. To achieve the above-mentioned purpose, the present invention provides the following technical scheme: a timed and quantitative addition device for preparing levofloxacin hydrochloride raw materials, comprising a conveying component, both ends of the upper surface of the conveying component are fixedly connected to a supporting component, the tops of the two supporting components are fixedly connected to a material storage frame, the bottoms of the two material storage frames are fixedly connected to a feed opening, and the two sides of the feed opening are opened as a through-opening structure, and the two sides of the through-opening of the feed opening are set as an extended slideway structure, and the slideways on both sides of the feed opening are slidably connected with a linkage closing component, and the upper and lower ends of the linkage closing component are respectively slidably connected to the top of the supporting component and the storage frame. The bottom of the material frame, and the top of one end of the first linkage closing component close to the second material storage frame is fixedly connected with a rotation-stopping sleeve rod, the four corners of the lower surface of the discharge port are fixedly connected with a tilting component, the interior of the supporting component is clamped with a reset quantitative component, the opposite sides of the two material storage frames are fixedly connected with a connecting component, the two ends of the connecting component are respectively penetrated and connected with a timing component and a material discharge component, the interior of the connecting component is fixedly connected with a reciprocating ejector rod assembly, and the reciprocating ejector rod assembly is located between the timing component and the material discharge component, and the reciprocating ejector rod assembly is meshedly connected with a reciprocating gear assembly on the side of the reciprocating ejector rod assembly facing the timing component; The reset quantitative assembly includes four limit slide bars, the side surfaces of the four limit slide bars are slidably connected in the card slot fixed block, and the four limit slide bars are grouped into two, and the opposite ends of the two limit slide bars in each group are fixedly connected with a rectangular block, one of the rectangular blocks is fixedly connected to the outward side with two telescopic card blocks, and the two ends of the upper surfaces of the two rectangular blocks are fixedly connected with a slide groove vertical plate, and the opposite side of each group of two slide groove vertical plates is penetrated and connected with an upper shaft rod, and the lower parts of the side surfaces of the two ends of the upper shaft rod are connected to the bottom slide bar through the folding shaft plate transmission, and the four folding shaft plates are grouped into two, and the lower surface of one end of the bottom slide bar inside the opposite side of the two slide groove vertical plates is fixedly connected with an upper pull spring, and the upper pull spring The lower surface of the spring is fixedly connected to the upper surface of the rectangular block, and one end of one group of folding axis plates facing away from each other is fixedly connected to a hook rod, and the outward ends of the two hook rods are fixedly connected to an outer push rod, and the two ends of the upper axis rods located on the opposite side of the slide groove vertical plate are sleeved with the outer push rod, and the side surfaces located on the opposite side of the two outer push rods are sleeved with T pressure rods and rotating gears in sequence, and the opposite side of each group of slide groove vertical plates is fixedly connected to a half-connecting plate, and the upper surface of the half-connecting plate is set as a slideway structure, and the two half-connecting plates are slidably connected to the slideways on the upper surfaces of the half-connecting plates. The opposite ends of the two traction tooth plates are axially connected to a flip top plate, and the other ends of the two flip top plates are rotatably connected to the shaft seats at the two ends of the lower surface of the upper pressure plate; The timing assembly includes a first double-rod tooth, the side surface of the first double-rod tooth is connected through the connecting plate, the first double-rod tooth extends to the connecting plate and is sleeved on the outward side surface thereof, the side surface of the sleeve is meshedly connected with a special-shaped gear, a secondary shaft is connected through the axis of the special-shaped gear, and the side surface of the secondary shaft is clamped in the arc groove at the top end of the anti-rotation sleeve, the secondary shaft passes through one end of the connecting plate and is sleeved with a needle rod, the side surface of the secondary shaft is sleeved with a special-shaped gear and a firing wheel, and the firing wheel faces the special-shaped tooth A protruding column is fixedly connected to one side of the wheel, and the side surface of the protruding column passes through the special-shaped gear and the connecting plate, the side surface of the secondary shaft rod passes through the ratchet gear, the side surface of the top end of the first double-rod teeth is meshedly connected with the second double-toothed rod, the side surface of the second double-toothed rod is meshedly connected with the third double-toothed rod, and the first double-rod teeth, the second double-toothed rod and the third double-toothed rod are all configured as a long gear and a wide gear structure, the side surface of the third double-toothed rod is meshedly connected with a single-toothed rotating rod, and the single-toothed rotating rod is fixedly connected with an escapement tooth at one end thereof facing the shifting tooth plate The escapement gear has an escapement lever movably connected to the upper side surface, a middle fixed lever is connected through the middle of the escapement lever, an upper fixed lever is connected through the top of the escapement lever, a balance wheel and a hairspring are sleeved on the side surface of the other end of the upper fixed lever, the side surface of the ratchet gear is meshedly connected to a single-rotation gear rod, the other end of the single-rotation gear rod is fixedly connected in a connecting plate, a tension wheel is sleeved on the side surface of the single-rotation gear rod, a stretching belt is fixedly connected to the side surface of the tension wheel, and a side of the middle part of the stretching belt facing inward is movably connected to the An auxiliary rotating wheel is connected, one end of the auxiliary rotating wheel is fixedly connected to the inner side of the connecting plate, the other end of the stretching belt is fixedly connected to a triangular rod, the bottom of the triangular rod is fixedly connected to a return spring, the side surface of the return spring is fixedly connected to the opposite side of the two connecting plates, the lower surface of the other end of the triangular rod is fixedly connected to a double-sided toothed plate, the other ends of the secondary shaft rod and the third double-toothed rod are penetrated and connected with a spring piece, the side surface of the spring piece is built with a guard frame, and the side surface of the guard frame is fixedly connected to the outward side of the connecting plate.

[0006] Preferably, the conveying assembly includes a base, the two ends of the upper surface of the base are fixedly connected to the lower surfaces of the two supporting assemblies, a door frame is fixedly connected to the middle of the upper surface of the base, fixed blocks are equidistantly distributed on both sides of the door frame, a plurality of fixed blocks are fixedly connected to the opposite sides of a central connecting block, a plurality of double-sided rotating wheel rods are penetrated and connected inside the central connecting block, the side surfaces of the plurality of double-sided rotating wheel rods are meshingly connected with a conveying toothed belt, one end of the base is fixedly connected to a discharge port, and a conveying motor is rotatably connected to the axis of the double-sided rotating wheel rods at the other end of the base, and the side surfaces of the conveying motor are fixedly connected to the same side of the base.

[0007] Preferably, the supporting assembly includes two lifting pallets, the lower surfaces of the two lifting pallets are fixedly connected to the upper surface of the base, and the interiors of the two lifting pallets are set as two multi-stage tooth hole structures, both ends of the two lifting pallets are fixedly connected with vertical rods, the opposite sides of the four vertical rods are fixedly connected with a slot block, and the four vertical rods are grouped into two, one of the lifting pallets is fixedly connected to two straight sliding rods on the outward side, and the two straight sliding rods are located on both sides of the multi-stage tooth hole structure of the lifting pallet, each group of vertical rods is fixedly connected to a side sliding rod on the opposite side, and the upper surfaces of the two side sliding rods are set as a slide structure, one end of the opposite side of the two groups of vertical rods is fixedly connected to a T rod, and the upper surfaces of the T rod are set as three slide structures.

[0008] Preferably, the linkage closing assembly includes two special-shaped sliders, the upper surfaces of the two special-shaped sliders are slidably connected to the inside of the feeding port, the middle parts of the upper surfaces of the two special-shaped sliders are fixedly connected to a baffle plate, the lower surfaces of the two opposite sides of the baffle plates are fixedly connected to an extended dial plate, the opposite sides of the two special-shaped sliders are fixedly connected to a first stop plate, the opposite ends of the two first stop plates are penetrated and connected to a first sliding rod, and the side surfaces of the two first sliding rods are slidably connected to the inside of the extended slideway structure of the feeding port, the side surface of the first sliding rod is rotatably connected to the first traction rod, and the first traction rod The other end is sleeved with a second sliding bar, and the lower surfaces of the two second sliding bars are slidably connected in the slideway of the side sliding bar, the side surface of the second sliding bar is penetrated and connected with a double-rod shift axis, and the lower surfaces of the two double-rod shift axes are slidably connected in the slideway on the upper surface of the T-bar cross bar, a third sliding bar is slidably connected in the slideway on the upper surface of the T-bar, and the side surfaces of the third sliding bar are respectively penetrated and connected with the other ends of the two double-rod shift axes, the side surface of the third sliding bar is penetrated and connected with a triangular straight bar, both ends of the triangular straight bar are penetrated and connected with limiting pull rods, and the lower surfaces of the two limiting pull rods are slidably connected in the slideways on the upper surfaces of the two straight sliding bars.

[0009] Preferably, the tilting assembly includes four rounded corner rods, the upper surfaces of the four rounded corner rods are fixedly connected to the four corners of the lower surface of the discharge port, and the four rounded corner rods are grouped into two, and the side surfaces of the two groups of rounded corner rods are respectively sleeved with an upper concave baffle and a lower concave plate, and at the same time, a positioning baffle is fixedly sleeved on the side surface of one group of rounded corner rods in the direction of the lower concave plate, the upper surfaces of both ends of the upper concave baffle are fixedly connected with return springs, the lower surfaces of both ends of the lower concave plate are connected with lower collars through return spring transmission, and the interiors of the two lower collars are connected to the side surfaces of the rounded corner rods, the upper surfaces of the upper concave baffle and the lower concave plate are movably connected with special-shaped flaps, the upper surfaces of the special-shaped flaps are fixedly connected with a hopper, and the lower surface of the special-shaped flaps The cam is fixedly connected to the lifting platform, and the cam is fixedly connected to the lifting platform by the spring, and the cam is connected to the lifting platform by the spring.

[0010] Preferably, the connecting component includes two connecting plates and two connecting rods, both sides of the two connecting plates and the connecting rods are fixedly connected to the opposite sides of the two storage frames, and the side surface of the connecting plate is set as an arc-shaped through-opening structure, and the opposite sides of the two connecting rods are fixedly connected with a cross-linking cross rod.

[0011] Preferably, the reciprocating gear assembly includes two series rods, and one end of the two series rods close to the double-sided toothed plates is penetrated and connected with the front half gears, and the opposite sides of the two front half gears are meshed and connected to the two sides of the double-sided toothed plates, and the rack positions of the two front half gears are in the same direction, and the other ends of the two series rods are penetrated and connected with the rear half gears, and the positions of the two rear half gears are staggered, the middle parts of the side surfaces of the two series rods are penetrated and connected with reciprocating middle teeth, and the middle parts of the opposite sides of the two reciprocating middle teeth are meshed and connected with linkage teeth, and the upper parts of the opposite sides of the two rear half gears are meshed and connected with upper connecting teeth, and the upper connecting teeth are fixedly connected with a reciprocating straight rod at the axis center of the side of the upper connecting teeth away from the double-sided toothed plates, and the other end of the reciprocating straight rod is penetrated and connected with a driving gear.

[0012] Preferably, the reciprocating push rod assembly includes a reciprocating slide, two ends of the reciprocating slide are respectively fixedly connected to one side of two connecting plates, the side surface of the reciprocating slide slideway is slidably connected with an upper sliding gear rod, the upper sliding gear rod is fixedly connected with a reciprocating toothed belt on the side facing the reciprocating gear assembly, and the reciprocating toothed belt is internally meshed with a driving gear, the rack on the top of the upper sliding gear rod is meshed with a push rod gear, the push rod gear is axially connected to a reciprocating rotating rod at the axis center on the side of the push rod gear away from the reciprocating gear assembly, one end of the reciprocating rotating rod is rotatably connected to a push wheel, and the side surface of the shaft rod between the push rod gear and the reciprocating rotating rod is connected to the opposite side of the two connecting plates through a sleeve rod.

[0013] Preferably, the discharge assembly includes an internal pressure spring, one end of the internal pressure spring is fixedly connected to the inner side of the connecting plate, one end of the internal pressure spring is fixedly connected to an extrusion rod, and the end of the extrusion rod facing the internal pressure spring is set to a trapezoidal structure, the other end of the extrusion rod is fixedly connected to a buckle plate, the inner side of the other end of the buckle plate is fixedly connected to a T-shaped pressure plate, a lower ladder baffle is built on the side of the extrusion rod facing the internal pressure spring, the top of the lower ladder baffle is fixedly connected to a discharge top plate, and the other end of the discharge top plate facing the lower ladder baffle is set to a semi-arc convex plate structure, the upper surface of the discharge top plate is fixedly connected to a baffle telescopic rod, and the side opposite to the discharge top plate and the baffle telescopic rod is fixedly connected to a baffle spring.

[0014] A method for using a device for adding raw materials to levofloxacin hydrochloride at a fixed time and in a fixed quantity, comprising the following steps: S1. First, add levofloxacin and N-methylpiperazine to two material storage frames respectively, then rotate the gear plate on the tooth side surface of the first double rod, adjust the pointing time of the gear plate according to the addition ratio and the time when levofloxacin reacts with the catalyst first, so as to control the time of N-methylpiperazine feeding, and stop the timing assembly from rotating and triggering by clamping the stop sleeve rod to the secondary shaft rod, and then twist the telescopic blocks in the two lifting cards according to the proportion weight to adjust the height of the reset quantitative assembly, and then twist the telescopic blocks again to fix them, start the conveying motor to rotate the connected double-sided rotating wheel rods, and synchronously drive the remaining double-sided rotating wheel rods to rotate through the conveying toothed belt; S2, then push the two triangular straight rods connected to each other inward, so that the third slide bar moves inward at one vertical end of the T-bar, and in the process of the third slide bar moving, the double-rod shifting axes on both sides are driven to slide at one horizontal end of the side slide bar in turn, and at the same time, the two second slide bars synchronously slide in the slideways at one end of the two side slide bars, and the first traction rods on the side surfaces of the two second slide bars synchronously pull the first abutment plates at both ends of the baffle plate to expand outward, and the two first slide bars slide in the slideways at both ends of the outlet of the interlayer of the discharge port to ensure that the first abutment plates can slide in a directional manner, and as the special-shaped sliders in the two baffle plates move in the interlayer of the discharge port to leak out of the discharge port, the levofloxacin begins to fall into the hopper; S3. As more raw materials fall, the weight of the hopper increases, and the special-shaped flap presses down the concave plate and the upper concave baffle until the lower surface of the special-shaped flap is pressed on the outer push rod. Then, during the rotation of the outer push rod, the upper shaft rod on the same side is driven to rotate, and the rotation of the upper shaft rod causes the T pressure rod and the rotating gear on the side surface to rotate. The rotating two upper shaft rods cause the hook rod and the outer push rod in the same direction to be pushed outward, and the outer push rod pushed outward will simultaneously pull the bottom slide bar below to slide on the vertical plate of the slide slot. At this time, the rotating rotating gear allows the traction tooth plate below to pass The meshing teeth are used to pull open the flip top plate, so that it is pushed upward, which makes the special-shaped flap disengage from the groove of the upper concave baffle plate, so that the special-shaped flap is tilted. At the same time, the T-pressure rod presses the lower pressure plate down at the same time according to the angle problem, so that the hopper is tilted. In the process of the hopper falling, the outer push rod pushed outward by the force makes the two pull outward, so that the baffle plate can be automatically closed to prevent further material discharge. On the other hand, the flipped hopper pours the raw materials into the upper surface of the conveyor belt to the slope of the discharge port, so that the raw materials and the catalyst are mixed in advance; S4. During the closing process, after the first abutment plate moving inward drives the anti-rotation sleeve rod to separate from the side surface of the secondary shaft rod, the twisted shifting tooth plate, under the action of the torque of the mainspring, drives the special-shaped gear and the ratchet gear to rotate under the rotation of the gear on the inner side of the first double-bar tooth located on the inner side of the connecting plate. Due to the one-way rack structure on the inner side of the ratchet gear, the outer surface of the ratchet gear will not rotate, and the other gear on the first double-bar tooth drives the second double-tooth rod, the third double-tooth rod, the single-tooth rotating rod and the escapement gear to rotate. At this time, when the rotating escapement gear is first driven by the escapement rod to rotate the balance wheel, the swinging hairspring will subsequently reciprocate and rotate the upper fixed rod, thereby shifting the escapement rod and the escapement gear back and forth to control the resistance. When the toothed disc rotates to the pointer position, the rotating first double-rod teeth drive the special-shaped gear to rotate, and the rotating special-shaped gear causes the needle bar to drive the convex column and the firing wheel to rotate, thereby causing the ratchet gear to rotate in the opposite direction and causing the side surface of the ratchet gear to rotate the single-rotation gear rod, and the rotating single-rotation gear rod causes the tension wheel to rotate, thereby pulling the stretching belt and the triangular rod to lift up, and after lifting up, the front half gear rotates, and the rotating front half gear causes the reciprocating middle gear and the rear half gear to rotate synchronously, and the linkage gear ensures that the reciprocating middle gear and the rear half gear on the other side rotate synchronously, and the rotating two rear half gears cause the upper linkage gear and the reciprocating straight rod to rotate, and finally the driving gear rotates; S5. As the tooth marks on the side surface of the active gear mesh with the reciprocating toothed belt, the upper sliding gear rod on one side of the reciprocating toothed belt is pulled to slide on the slideway on the upper surface of the reciprocating slide seat. The sliding upper sliding gear rod causes the top rod gear to rotate, thereby lifting the reciprocating rotating rod and the top wheel upward. During the lifting process, the top wheel lifts up the discharge top plate and the lower ladder baffle plate. The internal pressure spring is forced to pull the extrusion rod and the buckle plate, so that the T-shaped pressure plate is pressed down, and the linkage drives the baffle plate to expand, allowing N-methylpiperazine to start unloading. After reaching the corresponding weight, the unloading steps are repeated according to the levofloxacin unloading steps, and the unloading steps are reset under the pull of the corresponding spring.

[0015] Compared with the prior art, the present invention has the following beneficial effects: In the present invention, the discharge port is closed and opened by the slideway in the supporting component in cooperation with the linkage closing component when the front end distance control device is pulled. At the same time, during the raw material discharge process, the two lifting plates at the bottom of the supporting component cooperate with the tilting component to achieve a quantitative tilting effect and automatically unload during the tilting process.

[0016] In the present invention, the hopper can be lifted up and tilted to discharge materials by resetting the quantitative component. On the other hand, after the raw materials reach a certain weight, the outer push rod pushed open can link with the closing component to automatically close the discharge port to achieve the quantitative effect.

[0017] In the present invention, the material tilting assembly in the supporting assembly is used to help the raw materials to be automatically unloaded, and the linkage closing assembly sliding in the discharge port is used to automatically close the raw materials after they reach a certain weight. In addition, through the timing device, after the previous raw material is unloaded, the timing assembly is controlled by the anti-rotation sleeve to rotate in a linkage manner, and the next raw material is driven to be unloaded after the timing time is reached, so as to ensure the catalytic effect of the raw materials.

[0018] In the present invention, by resetting the quantitative component and the timing component, the material can be discharged at a certain time interval, wherein the reset quantitative component can move up and down according to the weight ratio of each raw material, so as to unload the material according to the weight adjustment, and only after the current raw material is unloaded and the timing component is operated, the next step of unloading will be carried out. The device is semi-automatic, which saves manpower and can be adjusted at any time according to different requirements. The adjustment method is convenient and simple to operate, and the overall equipment has low power requirements. While the device is energy-saving, it can also add subsequent storage frames and related structures to achieve the addition of more raw materials. It has wide versatility and strong adaptability. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 It is a schematic diagram of the three-dimensional left-view structure of the present invention; Figure 2 It is a schematic diagram of the three-dimensional right-view structure of the present invention; Figure 3 It is a schematic diagram of the material storage frame and the supporting assembly of the present invention; Figure 4 It is a schematic diagram of the feed opening, the supporting assembly and the material tilting assembly of the present invention; Figure 5 It is a schematic diagram of the linkage closing assembly of the present invention; Figure 6 It is a schematic diagram of the feed port and the supporting assembly of the present invention; Figure 7 It is a schematic diagram of the material dumping assembly of the present invention; Figure 8 It is an enlarged structural schematic diagram of the material dumping assembly of the present invention; Fig. 9 This is a schematic diagram of the structure of the reset quantitative component of the present invention; Fig.10 It is a schematic diagram of the structure of the conveying assembly of the present invention; Fig.11 It is a schematic diagram of the structure of the timing component and the discharge component of the present invention; Fig.12 It is a schematic structural diagram of the timing assembly, the reciprocating ejector assembly and the discharge assembly of the present invention; Fig.13 It is a schematic diagram of the structure of the reciprocating ejector assembly and the material discharge assembly of the present invention; Fig.14 It is a schematic diagram of the structure of the timing assembly and the reciprocating push rod assembly of the present invention; Fig.15 It is a schematic diagram of the enlarged structure of the timing component of the present invention; Fig.16 It is an enlarged structural schematic diagram of the reciprocating gear assembly of the present invention.

[0020] In the figure: 1. conveying assembly; 101. base; 102. discharge port; 103. fixed block; 104. door frame; 105. middle block; 106. double-side rotating wheel rod; 107. conveying motor; 108. conveying toothed belt; 2. supporting assembly; 201. lifting card plate; 202. vertical rod; 203. card slot fixed block; 204. straight slide rod; 205. side slide rod; 206. T rod; 3. storage frame; 4. discharge port; 5. linkage closing assembly; 501. special-shaped slider; 502. material blocking plate; 503. extended dial plate; 504. first stop plate; 505. first slide rod; 506. first traction rod; 507. second slide rod; 508. double rod shifting axis; 509. third slide rod; 5010. triangular straight rod; 6. anti-rotation 7. Material tilting assembly; 701. Rounded rod; 702. Positioning baffle; 703. Downward concave plate; 704. Lower collar; 705. Upper concave baffle; 706. Reset spring; 707. Vertical top plate; 708. Special-shaped flap; 709. Hopper; 7010. Net bag plate; 7011. Short spring pull rod; 7012. Tilt slide rod; 7013. Rocking rod; 7014. Tilt telescopic rod; 7015. Tilt spring; 7016. Lower pressure plate; 7017. Frame; 8. Reset quantitative assembly; 801. Limit slide rod; 802. Rectangle block; 803. Telescopic card block; 804. Slide groove vertical plate; 805. Upper shaft rod; 806. Folding shaft plate; 807. Bottom slide rod; 808. Upper pull spring; 809. Hook rod ;8010, outer push rod;8011, T pressure rod;8012, rotating gear;8013, half-connected plate;8014, traction tooth plate;8015, flip top plate;9, connecting component;901, connecting plate;902, connecting rod;903, cross-linking cross rod;10, timing component;1001, tooth plate;1002, first double rod teeth;1003, second double tooth rod;1004, third double tooth rod;1005, single tooth rotating rod;1006, escapement gear;1007, escapement rod;1008, upper fixed rod;1009, middle fixed rod;1010, balance wheel;1011, hairspring;1012, special-shaped gear;1013, firing wheel;1014, secondary shaft rod;1015, ratchet gear;1016, single rotating gear rod ; 1017, tension wheel; 1018, stretching belt; 1019, triangular rod; 1020, return spring; 1021, auxiliary wheel; 1022, double-sided tooth plate; 1023, spring piece; 1024, frame; 1025, needle rod; 1026, boss; 11, reciprocating gear assembly; 1101, series rod; 1102, rear half gear; 1103, reciprocating middle gear; 1104, front half gear; 1105, linkage gear; 1106, upper linkage gear; 1107, reciprocating straight rod; 1108, driving gear; 12, reciprocating push rod assembly; 1201, reciprocating slide seat; 1202, upper slide gear rod; 1203, reciprocating toothed belt; 1204, push rod gear; 1205, reciprocating rotating rod; 1206, top wheel;13. Material discharge assembly; 1301. Internal pressure spring; 1302. Extrusion rod; 1303. Buckle plate; 1304. T-type pressure plate; 1305. Lower ladder baffle; 1306. Material discharge top plate; 1307. Baffle telescopic rod; 1308. Baffle spring. ; DETAILED DESCRIPTION

[0021] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technical staff in this field without creative work are within the scope of protection of the present invention.

[0022] See also Figures 1 to 16 The present invention provides a technical solution: a timed and quantitative addition device for preparing levofloxacin hydrochloride raw materials, comprising a conveying component 1, both ends of the upper surface of the conveying component 1 are fixedly connected with a supporting component 2, the tops of the two supporting components 2 are fixedly connected with a material storage frame 3, the bottoms of the two material storage frames 3 are fixedly connected with a feed opening 4, and the two sides of the feed opening 4 are opened as a through-opening structure, and the two sides of the through-opening of the feed opening 4 are set as an extended slideway structure, and the slideways on both sides of the feed opening 4 are slidably connected with a linkage closing component 5, and the upper and lower ends of the linkage closing component 5 are respectively slidably connected to the top of the supporting component 2 and the bottom of the material storage frame 3, and the first A linkage closing component 5 is fixedly connected with a rotation-stopping sleeve rod 6 at the top of one end close to the second material storage frame 3, and a tilting component 7 is fixedly connected to the four corners of the lower surface of the material discharge port 4. A reset quantitative component 8 is clamped inside the supporting component 2, and a connecting component 9 is fixedly connected to the opposite side of the two material storage frames 3. The two ends of the connecting component 9 are respectively penetrated and connected with a timing component 10 and a material discharge component 13. A reciprocating push rod component 12 is fixedly connected inside the connecting component 9, and the reciprocating push rod component 12 is located between the timing component 10 and the material discharge component 13. The reciprocating push rod component 12 is meshedly connected with a reciprocating gear component 11 on the side facing the timing component 10; The reset quantitative component 8 includes four limit slide bars 801, and the side surfaces of the four limit slide bars 801 are slidably connected to the card slot fixed block 203, and the four limit slide bars 801 are grouped into two, and the opposite ends of the two limit slide bars 801 in each group are fixedly connected to a rectangular block 802, one of the rectangular blocks 802 is fixedly connected to two telescopic card blocks 803 on the outward side, and the two ends of the upper surfaces of the two rectangular blocks 802 are fixedly connected to a slide groove vertical plate 804, and the upper shaft rod 805 is penetrated and connected to the opposite side of each group of two slide groove vertical plates 804, and the lower parts of the side surfaces of both ends of the upper shaft rod 805 are transmission-connected to the bottom slide bar 807 through the folding shaft plate 806, and the four folding shaft plates 806 are grouped into two, and the lower surface of one end of the bottom slide bar 807 inside the opposite side of the two slide groove vertical plates 804 is fixedly connected to the upper pull spring 808, and the lower surface of the upper pull spring 808 is fixed The two ends of the two upper shaft rods 805 located on the opposite side of the slide groove vertical plate 804 are sleeved with the outer push rod 8010, and the side surfaces located on the opposite side of the two outer push rods 8010 are sleeved with T-pressure rods 8011 and rotating gears 8012 in sequence, and the opposite side of each group of slide groove vertical plates 804 is fixedly connected with a half-connecting plate 8013, and the upper surface of the half-connecting plate 8013 is set as a slideway structure, and the upper surface slideways of the two half-connecting plates 8013 are slidably connected with traction tooth plates 8014, and the opposite ends of the two traction tooth plates 8014 are axially connected with the flip top plate 8015, and the other ends of the two flip top plates 8015 are rotatably connected with the shaft seats at the two ends of the lower surface of the upper pressure plate 8016; The timing assembly 10 includes a first double-rod tooth 1002, the side surface of which is connected to the connecting plate 901, and the first double-rod tooth 1002 extends to the connecting plate 901, and the side surface facing outward is sleeved with a gear shifting plate 1001, and the side surface of the gear shifting plate 1001 is meshingly connected with a special-shaped gear 1012, and the axis of the special-shaped gear 1012 is penetrated by a secondary shaft rod 1014, and the side surface of the secondary shaft rod 1014 is clamped in the arc groove at the top of the anti-rotation sleeve rod 6, and the secondary shaft rod 1014 penetrates one end of the connecting plate 901 and is sleeved with a needle rod 1025, and the side surface of the secondary shaft rod 1014 is sleeved with a special-shaped gear 1012 and a firing wheel 1013, and the firing wheel 1013 faces the special-shaped tooth. A protruding column 1026 is fixedly connected to one side of the wheel 1012, and the side surface of the protruding column 1026 passes through the special-shaped gear 1012 and the connecting plate 901, and the side surface of the secondary shaft 1014 passes through the ratchet gear 1015. The side surface of the top of the first double-toothed rod 1002 is meshedly connected to the second double-toothed rod 1003, and the side surface of the second double-toothed rod 1003 is meshedly connected to the third double-toothed rod 1004, and the first double-toothed rod 1002, the second double-toothed rod 1003 and the third double-toothed rod 1004 are all configured as a long gear and a wide gear structure, and the side surface of the third double-toothed rod 1004 is meshedly connected to the single-toothed rotating rod 1005, and the single-toothed rotating rod 1005 is fixedly connected to one end thereof facing the shifting tooth plate 1001. The escapement gear 1006 has an escapement rod 1007 movably connected to the upper side surface of the escapement gear 1006, a middle fixed rod 1009 is connected through the middle of the escapement rod 1007, an upper fixed rod 1008 is connected through the top of the escapement rod 1007, a balance wheel 1010 and a hairspring 1011 are sleeved on the side surface of the other end of the upper fixed rod 1008, a ratchet gear 1015 is meshedly connected to a single-turn gear rod 1016, the other end of the single-turn gear rod 1016 is fixedly connected in the connecting plate 901, a tension wheel 1017 is sleeved on the side surface of the single-turn gear rod 1016, a tension wheel 1017 is fixedly connected to the side surface of the tension wheel 1017, and a tension belt 1018 is fixedly connected to the side surface of the tension wheel 1017, and a side of the middle part of the tension belt 1018 facing inward is movably connected. An auxiliary rotating wheel 1021 is dynamically connected, one end of the auxiliary rotating wheel 1021 is fixedly connected to the inner side of the connecting plate 901, the other end of the stretching belt 1018 is fixedly connected to a triangular rod 1019, the bottom of the triangular rod 1019 is fixedly connected to a return spring 1020, the side surface of the return spring 1020 is fixedly connected to the opposite side of the two connecting plates 901, the lower surface of the other end of the triangular rod 1019 is fixedly connected to a double-sided toothed plate 1022, the other ends of the secondary shaft rod 1014 and the third double-toothed rod 1004 are penetrated and connected with a spring piece 1023, the side surface of the spring piece 1023 is built with a protective frame 1024, and the side surface of the protective frame 1024 is fixedly connected to the outward side of the connecting plate 901.

[0023] The conveying component 1 includes a base 101, the two ends of the upper surface of the base 101 are fixedly connected to the lower surfaces of the two supporting components 2, a door frame 104 is fixedly connected to the middle of the upper surface of the base 101, and fixed blocks 103 are equidistantly distributed on both sides of the door frame 104, and a central connecting block 105 is fixedly connected to the opposite side of the multiple fixed blocks 103, and a plurality of double-sided rotating wheel rods 106 are connected through the inside of the central connecting block 105, and the side surfaces of the multiple double-sided rotating wheel rods 106 are meshed with conveying toothed belts 108. One end of the base 101 is fixedly connected to the discharge port 102, and the other end of the base 101 is rotatably connected to the axis of the double-sided rotating wheel rods 106. The side surfaces of the conveying motor 107 are fixedly connected to the same side of the base 101.

[0024] The supporting assembly 2 includes two lifting cards 201, the lower surfaces of the two lifting cards 201 are fixedly connected to the upper surface of the base 101, and the interiors of the two lifting cards 201 are set as two multi-stage tooth hole structures, both ends of the two lifting cards 201 are fixedly connected with vertical rods 202, the opposite sides of the four vertical rods 202 are fixedly connected with a slot block 203, and the four vertical rods 202 are grouped into two, one side of one lifting card 201 facing outward is fixedly connected with two straight sliding rods 204, and the two straight sliding rods 204 are located on both sides of the multi-stage tooth hole structure of the lifting card 201, each group of vertical rods 202 is fixedly connected with a side sliding rod 205 on the opposite side, and the upper surfaces of the two side sliding rods 205 are set as a slide structure, one end of the opposite side of the two groups of vertical rods 202 is fixedly connected with a T rod 206, and the upper surfaces of the T rod 206 are set as three slide structures.

[0025] The linkage closing component 5 includes two special-shaped sliders 501, the upper surfaces of the two special-shaped sliders 501 are slidably connected to the inside of the discharge port 4, the middle parts of the upper surfaces of the two special-shaped sliders 501 are fixedly connected with a baffle plate 502, the lower surfaces of the opposite sides of the two baffle plates 502 are fixedly connected with an extended dial plate 503, the opposite sides of the two special-shaped sliders 501 are fixedly connected with a first abutment plate 504, the opposite ends of the two first abutment plates 504 are penetrated and connected with a first slide bar 505, and the side surfaces of the two first slide bars 505 are slidably connected to the inside of the extended slideway structure of the discharge port 4, the side surface of the first slide bar 505 is rotatably connected with a first traction rod 506, and the other end of the first traction rod 506 is sleeved with a second slide bar 5 07, and the lower surfaces of the two second sliding bars 507 are both slidably connected in the slideway of the side sliding bar 205, the side surface of the second sliding bar 507 is penetrated and connected with a double-rod shift shaft 508, and the lower surfaces of the two double-rod shift shafts 508 are slidably connected in the slideway on the upper surface of the T-bar 206 cross bar, and a third sliding bar 509 is slidably connected in the slideway on the upper surface of the T-bar 206, and the side surfaces of the third sliding bar 509 are respectively penetrated and connected with the other ends of the two double-rod shift shafts 508, the side surface of the third sliding bar 509 is penetrated and connected with a triangular straight bar 5010, both ends of the triangular straight bar 5010 are penetrated and connected with a limiting pull rod 5011, and the lower surfaces of the two limiting pull rods 5011 are slidably connected in the slideway on the upper surfaces of the two straight sliding bars 204.

[0026] The tilting assembly 7 includes four rounded corner rods 701, the upper surfaces of the four rounded corner rods 701 are fixedly connected to the four corners of the lower surface of the discharge port 4, and the four rounded corner rods 701 are grouped in pairs, and the side surfaces of the two groups of rounded corner rods 701 are respectively sleeved with an upper concave baffle 705 and a downward concave plate 703, and at the same time, a positioning baffle 702 is fixedly sleeved on the side surface of one group of rounded corner rods 701 in the direction of the downward concave plate 703, and the upper surfaces of both ends of the upper concave baffle 705 are fixedly connected with a reset The lower surfaces of both ends of the downward concave plate 703 are connected to the lower rings 704 through the return spring 706, and the inner parts of the two lower rings 704 are connected to the side surfaces of the rounded rods 701, the upper concave baffle 705 and the upper surfaces of the downward concave plate 703 are movably connected to the special-shaped flap 708, the upper surface of the special-shaped flap 708 is fixedly connected to the hopper 709, and the lower surface of the special-shaped flap 708 is fixedly connected to the net bag plate 7010, and the special-shaped flap 708 is fixedly connected to the net bag plate 7010. A lower pressure plate 7016 is fixedly connected between the two sides of the special-shaped flap 708 and the net bag plate 7010, and two inclined telescopic rods 7014 are fixedly connected to the two ends of the other two sides of the special-shaped flap 708, and the side surfaces of the four inclined telescopic rods 7014 are sleeved with inclined springs 7015, the four inclined telescopic rods 7014 are grouped into two, and the opposite end of each group of two inclined telescopic rods 7014 is fixedly connected to a rocking rod 7013, and one end of the bottom of the rocking rod 7013 and the two ends of the other two sides of the special-shaped flap 708 are set as a rotating shaft rod structure, one end of the top of the rocking rod 7013 is slidably connected to the vertical top plate 707 through an inclined sliding rod 7012, and the upper surface of the middle part of the inclined sliding rod 7012 is transmission-connected to the lower surface of the protrusion of the vertical top plate 707 through a short spring pull rod 7011, and the bottom of the rounded rod 701 is fixedly connected to a frame 7017, and the lower surface of the frame 7017 is fixedly connected to the two ends of the upper surface of the base 101.

[0027] The connecting component 9 includes two connecting plates 901 and two connecting rods 902. Both sides of the two connecting plates 901 and the connecting rods 902 are fixedly connected to the opposite sides of the two storage frames 3, and the side surface of the connecting plate 901 is set as an arc-shaped through-opening structure. The opposite side of the two connecting rods 902 is fixedly connected with a cross-linking cross rod 903.

[0028] The reciprocating gear assembly 11 includes two serial rods 1101, and one end of the two serial rods 1101 close to the double-sided toothed plates 1022 is penetrated and connected with a front half gear 1104, and the opposite sides of the two front half gears 1104 are meshed and connected to the two sides of the double-sided toothed plates 1022, and the rack positions of the two front half gears 1104 are in the same direction, and the other ends of the two serial rods 1101 are penetrated and connected with a rear half gear 1102, and the positions of the two rear half gears 1102 are in the same direction. Wrong, the middle parts of the side surfaces of the two serial rods 1101 are penetrated by reciprocating middle teeth 1103, and the middle parts of the opposite sides of the two reciprocating middle teeth 1103 are meshed with linkage teeth 1105, and the upper parts of the opposite sides of the two rear half gears 1102 are meshed with upper connecting teeth 1106, and the upper connecting teeth 1106 are fixedly connected with a reciprocating straight rod 1107 at the axis away from the double-sided tooth plates 1022, and the other end of the reciprocating straight rod 1107 is penetrated by a driving gear 1108.

[0029] The reciprocating push rod assembly 12 includes a reciprocating slide 1201, two ends of the reciprocating slide 1201 are respectively fixedly connected to the opposite sides of the two connecting plates 901, the side surface of the slideway of the reciprocating slide 1201 is slidably connected with an upper sliding gear rod 1202, the upper sliding gear rod 1202 is fixedly connected with a reciprocating toothed belt 1203 on the side facing the reciprocating gear assembly 11, and the reciprocating toothed belt 1203 is internally meshed with a driving gear 1108, the rack at the top of the upper sliding gear rod 1202 is meshed with a push rod gear 1204, the push rod gear 1204 is axially connected to a reciprocating rotating rod 1205 at the axis center of the side away from the reciprocating gear assembly 11, one end of the reciprocating rotating rod 1205 is rotatably connected to a top wheel 1206, and the side surface of the shaft between the push rod gear 1204 and the reciprocating rotating rod 1205 is connected to the opposite side of the two connecting plates 901 through a sleeve rod.

[0030] The discharge assembly 13 includes an inner pressure spring 1301, one end of the inner pressure spring 1301 is fixedly connected to the inner side of the connecting plate 901, one end of the inner pressure spring 1301 is fixedly connected to an extrusion rod 1302, and the extrusion rod 1302 is set to a trapezoidal structure toward one end of the inner pressure spring 1301, the other end of the extrusion rod 1302 is fixedly connected to a buckle plate 1303, and the inner side of the other end of the buckle plate 1303 is fixedly connected to a T-shaped pressure plate 1304, and the extrusion rod 130 A lower ladder baffle 1305 is built on one side facing the inner pressure spring 1301, a material discharge top plate 1306 is fixedly connected to the top of the lower ladder baffle 1305, and the other end of the material discharge top plate 1306 facing the lower ladder baffle 1305 is set as a semi-arc convex plate structure, a baffle telescopic rod 1307 is fixedly connected to the upper surface of the material discharge top plate 1306, and a baffle spring 1308 is fixedly connected to the side opposite to the material discharge top plate 1306 and the baffle telescopic rod 1307.

[0031] A method for using a device for adding raw materials to levofloxacin hydrochloride at a fixed time and in a fixed quantity, comprising the following steps: S1. First, add levofloxacin and N-methylpiperazine to the two material storage frames 3 respectively, then rotate the toothed disc 1001 on the side surface of the first double-rod tooth 1002, adjust the pointing time of the toothed disc 1001 according to the addition ratio and the time for the levofloxacin to react with the catalyst first, so as to control the time of N-methylpiperazine unloading, and the timing component 10 stops rotating and triggers by the clamping of the stop sleeve 6 to the secondary shaft 1014, and then twist the telescopic blocks 803 in the two lifting cards 201 according to the proportional weight to adjust the height of the reset quantitative component 8, and then twist the telescopic blocks 803 again to fix them, and start the conveying motor 107 to rotate the connected double-sided rotating wheel rods 106, and synchronously drive the remaining double-sided rotating wheel rods 106 to rotate through the conveying toothed belt 108; S2, then push the two 5011 inward to drive the interlinked triangular straight rods 5010, so that the third slide bar 509 moves inward at one vertical end of the T rod 206, and in the process of the third slide bar 509 moving, the double-rod shifting shaft 508 on both sides is driven to slide at one horizontal end of the side slide bar 205 in turn, at the same time, the two second slide bars 507 slide synchronously in the slideways at one end of the two side slide bars 205, and the first traction rods 506 on the side surfaces of the two second slide bars 507 synchronously pull the first abutment plates 504 at both ends of the baffle plate 502 to expand outward, and the two first slide bars 505 slide in the slideways at both ends of the interlayer outlet of the discharge port 4 to ensure that the first abutment plates 504 can slide in a directional manner, as the special-shaped sliders 501 in the two baffle plates 502 move in the interlayer of the discharge port 4 to leak out of the discharge port, at this time, the levofluorocarboxylic acid begins to fall into the hopper 709; S3. As more raw materials fall, the weight of the hopper 709 increases, and the concave plate 703 and the upper concave baffle 705 are pressed down by the special-shaped flap 708 until the lower surface of the special-shaped flap 708 is pressed on the outer push rod 8010. Then, during the rotation of the outer push rod 8010, the upper shaft rod 805 on the same side is driven to rotate, and the rotation of the upper shaft rod 805 causes the T pressure rod 8011 and the rotating gear 8012 on the side surface to rotate. The two rotating upper shaft rods 805 cause the hook rod 809 and the outer push rod 8010 in the same direction to be pushed outward, and the outer push rod 8010 pushed outward will simultaneously pull the bottom slide bar 807 below to slide on the slide groove vertical plate 804. At this time, the rotating rotating gear 8012 allows the traction tooth plate below to 8014 pulls open the flip top plate 8015 through the meshing teeth, so that 8016 is pushed up, and the lifted 8016 makes the special-shaped flap 708 disengage from the groove of the upper concave baffle 705, so that the special-shaped flap 708 is tilted up, and at the same time, the T-pressure rod 8011 presses the lower pressure plate 7016 down at the same time due to the angle problem, so that the hopper 709 tilts, and in the process of the hopper 709 falling, the outer push rod 8010 pushed outward by the force makes the two 5011 pull outward, so that the baffle plate 502 can be automatically closed to prevent further material discharge, and on the other hand, the flipped hopper 709 pours the raw materials into the upper surface of the conveyor belt 108 to the slope of the discharge port 102, so that the raw materials and the catalyst are mixed in advance; S4, during the closing process, after the first abutment plate 504 moving inward drives the anti-rotation sleeve rod 6 to disengage from the side surface of the secondary shaft rod 1014, the twisted shifting tooth plate 1001, under the torsion of the mainspring piece 1023, drives the special-shaped gear 1012 and the ratchet gear 1015 to rotate under the rotation of the gear on the inner side of the first double-rod tooth 1002 located on the inner side of the connecting plate 901. Due to the one-way rack structure on the inner side of the ratchet gear 1015, the outer surface of the ratchet gear 1015 will not rotate. , and the other gear of the first double-toothed bar 1002 drives the second double-toothed bar 1003, the third double-toothed bar 1004, the single-toothed rotating bar 1005 and the escapement gear 1006 to rotate. At this time, when the escapement gear 1006 is initially driven by the escapement rod 1007 to rotate the balance wheel 1010, the swinging hairspring 1011 subsequently reciprocates and rotates the upper fixed rod 1008 to move the escapement rod 1007 and the escapement gear 1006 back and forth, and the resistance is controlled, and the gear plate is waited for. After 1001 rotates to the pointer position, the rotating first double-rod tooth 1002 drives the special-shaped gear 1012 to rotate, and the rotating special-shaped gear 1012 causes the needle rod 1025 to move the protruding column 1026 and the firing wheel 1013 to rotate, thereby causing the ratchet gear 1015 to rotate in the opposite direction and causing the side surface of the ratchet gear 1015 to rotate the single-rotation gear rod 1016, and the rotating single-rotation gear rod 1016 causes the tension wheel 1017 to rotate, thereby pulling the tension belt 1018 and the triangular rod 1019 are lifted up, and the front half gear 1104 is rotated after being lifted up. The rotating front half gear 1104 makes the reciprocating middle gear 1103 and the rear half gear 1102 rotate synchronously, and the linkage gear 1105 ensures that the reciprocating middle gear 1103 and the rear half gear 1102 on the other side rotate synchronously. The rotating two rear half gears 1102 make the upper linkage gear 1106 and the reciprocating straight rod 1107 rotate, and finally the driving gear 1108 rotates; S5. As the tooth marks on the side surface of the active gear 1108 mesh with the reciprocating toothed belt 1203, the upper sliding gear rod 1202 on one side of the reciprocating toothed belt 1203 is pulled to slide on the slideway on the upper surface of the reciprocating slide seat 1201. The sliding upper sliding gear rod 1202 causes the top rod gear 1204 to rotate, thereby lifting the reciprocating rotating rod 1205 and the top wheel 1206 upward. During the lifting process, the top wheel 1206 lifts up the discharge top plate 1306 and the lower ladder baffle 1305, and the internal pressure spring 1301 is forced to pull the extrusion rod 1302 and the buckle plate 1303, so that the T-shaped pressure plate 1304 is pressed down 5011, which in turn drives the baffle plate 502 to unfold, allowing N-methylpiperazine to start unloading. After reaching the corresponding weight, the levofloxacin unloading steps are followed, and the discharge steps are repeated, and reset under the pull of the corresponding spring.

[0032] The above shows and describes the basic principles, main features and advantages of the present invention. Technical personnel in this industry should understand that the present invention is not limited to the above embodiments. The above embodiments and descriptions are only preferred examples of the present invention and are not used to limit the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, which fall within the scope of the present invention to be protected. The scope of protection of the present invention is defined by the attached claims and their equivalents.

Claims

1. A timed and quantitative addition device for preparing levofloxacin hydrochloride raw materials, comprising a conveying component (1), both ends of the upper surface of the conveying component (1) are fixedly connected to a supporting component (2), the tops of the two supporting components (2) are fixedly connected to a material storage frame (3), the bottoms of the two material storage frames (3) are fixedly connected to a feeding port (4), and the two sides of the feeding port (4) are provided with a through-port structure, and the two sides of the through-port of the feeding port (4) are provided with an extended slideway structure, and the slideways on both sides of the feeding port (4) are slidably connected to a linkage closing component (5), and the upper and lower ends of the linkage closing component (5) are respectively slidably connected to the top of the supporting component (2) and the bottom of the material storage frame (3), and the first linkage closing component (5) is close to the first linkage closing component (5). A stop sleeve rod (6) is fixedly connected to the top of one end of the second material storage frame (3); a tilting assembly (7) is fixedly connected to the four corners of the lower surface of the discharge port (4); a reset quantitative assembly (8) is clamped inside the support assembly (2); a connecting assembly (9) is fixedly connected to the opposite sides of the two material storage frames (3); the two ends of the connecting assembly (9) are respectively penetrated and connected with a timing assembly (10) and a discharge assembly (13); a reciprocating push rod assembly (12) is fixedly connected inside the connecting assembly (9); the reciprocating push rod assembly (12) is located between the timing assembly (10) and the discharge assembly (13); and a reciprocating gear assembly (11) is meshedly connected inside the side of the reciprocating push rod assembly (12) facing the timing assembly (10); The reset quantitative assembly (8) comprises four limit slide bars (801), the side surfaces of the four limit slide bars (801) are all slidably connected in the card slot fixed block (203), and the four limit slide bars (801) are grouped in two, and the opposite ends of the two limit slide bars (801) in each group are fixedly connected to rectangular blocks (802), one of the rectangular blocks (802) is fixedly connected to the outward side with two telescopic card blocks (803), and the two ends of the upper surfaces of the two rectangular blocks (802) are fixedly connected to the two telescopic card blocks (803). A slide groove vertical plate (804) is connected, and an upper shaft rod (805) is connected through the opposite side of each group of two slide groove vertical plates (804). The lower sides of the side surfaces of both ends of the upper shaft rod (805) are both connected to the bottom slide rod (807) through the folding shaft plate (806), and the four folding shaft plates (806) form a group of two. The lower surface of one end of the bottom slide rod (807) inside the opposite side of the two slide groove vertical plates (804) is fixedly connected to the upper pull spring (808), and the lower surface of the upper pull spring (808) The upper surface of the rectangular block (802) is fixedly connected to the upper surface of the rectangular block (802), and one end of one set of folding shaft plates (806) facing away from each other is fixedly connected to a hook rod (809), and the outward ends of the two hook rods (809) are fixedly connected to an outer push rod (8010), and the two ends of the two upper shaft rods (805) located on the opposite side of the slide groove vertical plate (804) are sleeved with the outer push rod (8010), and the side surfaces located on the opposite side of the two outer push rods (8010) are sleeved with a T-type pressure rod (8011) and a rotating gear (8010) in sequence. 012), a half-connecting plate (8013) is fixedly connected to the opposite side of each group of the slide groove vertical plates (804), and the upper surface of the half-connecting plate (8013) is set as a slideway structure, and the two half-connecting plates (8013) are slidably connected to the slideways on the upper surfaces of the two half-connecting plates (8013), and the opposite ends of the two traction tooth plates (8014) are axially connected to the flip top plates (8015), and the other ends of the two flip top plates (8015) are rotatably connected to the shaft seats at the two ends of the lower surface of the upper pressure plate (8016); The timing assembly (10) comprises a first double-rod tooth (1002), the side surface of the first double-rod tooth (1002) is connected to the connecting plate (901), the first double-rod tooth (1002) extends to the connecting plate (901) and is sleeved with a toothed disc (1001) on its outward side surface, the side surface of the toothed disc (1001) is meshingly connected with a special-shaped gear (1012), the axis of the special-shaped gear (1012) is connected to a secondary shaft (1014), and the side surface of the secondary shaft (1014) is clamped in an arc groove at the top end of the anti-rotation sleeve (6), one end of the secondary shaft (1014) that passes through the connecting plate (901) is sleeved with a needle rod (1025), and the side surface of the secondary shaft (1014) is sleeved with a needle rod (1025). A special-shaped gear (1012) and a firing wheel (1013) are provided, and a protruding column (1026) is fixedly connected to the firing wheel (1013) on one side facing the special-shaped gear (1012), and the side surface of the protruding column (1026) penetrates the special-shaped gear (1012) and the connecting plate (901), and a ratchet gear (1015) is penetrated and connected to the side surface of the secondary shaft (1014), and the side surface of the top end of the first double-toothed rod (1002) is meshedly connected to the second double-toothed rod (1003), and the side surface of the second double-toothed rod (1003) is meshedly connected to the third double-toothed rod (1004), and the first double-toothed rod (1002), the second double-toothed rod (1003) and the third double-toothed rod (1004) are all configured as a long gear and a wide gear structure. The side surface of the third double-toothed rod (1004) is meshedly connected with a single-toothed rotating rod (1005); one end of the single-toothed rotating rod (1005) facing the shifting tooth plate (1001) is fixedly connected with an escapement gear (1006); an escapement rod (1007) is movably connected above the side surface of the escapement gear (1006); a middle fixed rod (1009) is penetrated through the middle of the escapement rod (1007); an upper fixed rod (1008) is penetrated through the top of the escapement rod (1007); a balance wheel (1010) and a hairspring (1011) are sleeved on the side surface of the other end of the upper fixed rod (1008); a side surface of the ratchet gear (1015) is meshedly connected with a single-toothed rod (1016); and the single-toothed rod (101 6) is fixedly connected to the connecting plate (901), the side surface of the single-rotating gear rod (1016) is sleeved with a tension wheel (1017), the side surface of the tension wheel (1017) is fixedly connected to a stretching belt (1018), the middle side of the stretching belt (1018) facing inward is movably connected to an auxiliary wheel (1021), one end of the auxiliary wheel (1021) is fixedly connected to the inner side of the connecting plate (901), the other end of the stretching belt (1018) is fixedly connected to a triangular rod (1019), the bottom of the triangular rod (1019) is fixedly connected to a return spring (1020), the side surface of the return spring (1020) is fixedly connected to the opposite side of the two connecting plates (901),The lower surface of the other end of the triangular rod (1019) is fixedly connected to a double-sided toothed plate (1022), the other ends of the secondary shaft rod (1014) and the third double-toothed rod (1004) are penetrated and connected to a spring piece (1023), the side surface of the spring piece (1023) is built with a protective frame (1024), and the side surface of the protective frame (1024) is fixedly connected to the outward side of the connecting plate (901).

2. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 1, characterized in that: The conveying assembly (1) comprises a base (101), the two ends of the upper surface of the base (101) are fixedly connected to the lower surfaces of the two supporting assemblies (2), a door frame (104) is fixedly connected to the middle of the upper surface of the base (101), fixed blocks (103) are evenly distributed on both sides of the door frame (104), a central connecting block (105) is fixedly connected to the opposite side of the plurality of fixed blocks (103), a plurality of double-sided rotating wheel rods (106) are connected through the interior of the central connecting block (105), and the side surfaces of the plurality of double-sided rotating wheel rods (106) are meshedly connected to a conveying toothed belt (108), one end of the base (101) is fixedly connected to a discharge port (102), and a conveying motor (107) is rotatably connected to the axis of the double-sided rotating wheel rods (106) at the other end of the base (101), and the side surface of the conveying motor (107) is fixedly connected to the same side of the base (101).

3. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 2, characterized in that: The supporting assembly (2) comprises two lifting cards (201), the lower surfaces of the two lifting cards (201) are fixedly connected to the upper surface of the base (101), and the interiors of the two lifting cards (201) are configured as two multi-stage tooth hole structures, both ends of the two lifting cards (201) are fixedly connected to vertical rods (202), the opposite sides of the four vertical rods (202) are fixedly connected to a card slot fixed block (203), and the four vertical rods (202) are grouped in two, one of which is The lifting card plate (201) is fixedly connected to one side facing outward with two straight sliding rods (204), and the two straight sliding rods (204) are located on both sides of the multi-stage tooth hole structure of the lifting card plate (201); the opposite side of each group of vertical rods (202) is fixedly connected to a side sliding rod (205), and the upper surfaces of the two side sliding rods (205) are set as a slideway structure; one end of the opposite side of the two groups of vertical rods (202) is fixedly connected to a T rod (206), and the upper surfaces of the T rod (206) are set as three slideway structures.

4. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 3, characterized in that: The linkage closing component (5) comprises two special-shaped sliders (501), the upper surfaces of the two special-shaped sliders (501) are slidably connected to the inside of the material discharge port (4), the middle parts of the upper surfaces of the two special-shaped sliders (501) are fixedly connected to a material blocking plate (502), the lower surfaces of the two opposite sides of the two material blocking plates (502) are fixedly connected to an extended dial plate (503), the opposite sides of the two special-shaped sliders (501) are fixedly connected to a first abutment plate (504), the opposite ends of the two first abutment plates (504) are penetrated and connected to a first sliding rod (505), and the side surfaces of the two first sliding rods (505) are slidably connected to the inside of the extended slideway structure of the material discharge port (4), the side surface of the first sliding rod (505) is rotatably connected to a first traction rod (506), and the other end of the first traction rod (506) is sleeved with a first The second sliding rod (507) is provided with a plurality of sliding rods (507), and the lower surfaces of the two second sliding rods (507) are both slidably connected in the slideway of the side sliding rod (205); the side surface of the second sliding rod (507) is penetrated and connected with a double-rod shift shaft (508), and the lower surfaces of the two double-rod shift shafts (508) are slidably connected in the slideway on the upper surface of the T-bar (206); a third sliding rod (509) is slidably connected in the slideway on the upper surface of the T-bar (206), and the side surfaces of the third sliding rod (509) are respectively penetrated and connected with the other ends of the two double-rod shift shafts (508); the side surface of the third sliding rod (509) is penetrated and connected with a triangular straight rod (5010), and both ends of the triangular straight rod (5010) are penetrated and connected with a limiting pull rod (5011), and the lower surfaces of the two limiting pull rods (5011) are slidably connected in the slideway on the upper surfaces of the two straight sliding rods (204).

5. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 4, characterized in that: The tilting assembly (7) comprises four rounded corner rods (701), the upper surfaces of the four rounded corner rods (701) are fixedly connected to the four corners of the lower surface of the discharge port (4), and the four rounded corner rods (701) are grouped in pairs, and the side surfaces of the two groups of rounded corner rods (701) are respectively sleeved with an upper concave baffle (705) and a downward concave plate (703), and at the same time, the side surface of the group of rounded corner rods (701) in the direction of the downward concave plate (703) is fixedly sleeved with a positioning baffle (702), and the upper surfaces of both ends of the upper concave baffle (705) are fixedly connected with The lower surfaces of both ends of the downward concave plate (703) are connected to lower collars (704) through the return springs (706), and the interiors of the two lower collars (704) are connected to the side surfaces of the rounded rods (701). The upper concave baffle (705) and the upper surfaces of the downward concave plate (703) are movably connected to special-shaped flaps (708), the upper surfaces of the special-shaped flaps (708) are fixedly connected to a hopper (709), and the lower surfaces of the special-shaped flaps (708) are fixedly connected to a net bag plate (709). 010), and a lower pressure plate (7016) is fixedly connected between the two sides of the special-shaped flap (708) and the net bag plate (7010), two inclined telescopic rods (7014) are fixedly connected to the two ends of the other two sides of the special-shaped flap (708), and the side surfaces of the four inclined telescopic rods (7014) are sleeved with inclined springs (7015), the four inclined telescopic rods (7014) are grouped into two, and the opposite ends of each group of two inclined telescopic rods (7014) are fixedly connected to a rocking rod (7013), and the bottom of the rocking rod (7013) is fixedly connected to the bottom of the rocking rod (7013). One end of the part and the two ends of the other two sides of the special-shaped flap (708) are set as a rotating shaft rod structure, one end of the top of the rocking rod (7013) is slidably connected to the vertical top plate (707) through an inclined sliding rod (7012), and the upper surface of the middle part of the inclined sliding rod (7012) is transmission-connected to the lower surface of the protrusion of the vertical top plate (707) through a short spring pull rod (7011), and the bottom of the rounded rod (701) is fixedly connected to a frame (7017), and the lower surface of the frame (7017) is fixedly connected to the two ends of the upper surface of the base (101).

6. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 5, characterized in that: The connecting component (9) comprises two connecting plates (901) and two connecting rods (902), both sides of the two connecting plates (901) and the connecting rods (902) are fixedly connected to opposite sides of two material storage frames (3), and the side surface of the connecting plate (901) is configured as an arc-shaped through-hole structure, and opposite sides of the two connecting rods (902) are fixedly connected with a cross-linking cross rod (903).

7. A timed and quantitative addition device for preparing raw materials for levofloxacin hydrochloride according to claim 6, characterized in that: The reciprocating gear assembly (11) comprises two serial rods (1101), one end of the two serial rods (1101) close to the double-sided toothed plates (1022) is penetrated and connected with a front half gear (1104), and the opposite sides of the two front half gears (1104) are meshed and connected to the two sides of the double-sided toothed plates (1022), and the rack positions of the two front half gears (1104) are in the same direction, and the other ends of the two serial rods (1101) are penetrated and connected with a rear half gear (1102), and the positions of the two rear half gears (1102) are staggered. The middle parts of the side surfaces of the two serial rods (1101) are penetrated by reciprocating middle teeth (1103), and the middle parts of the two reciprocating middle teeth (1103) on the opposite side are meshedly connected with linkage teeth (1105), and the upper parts of the two rear half gears (1102) on the opposite side are meshedly connected with upper linkage teeth (1106), and the upper linkage teeth (1106) are fixedly connected with a reciprocating straight rod (1107) at the axis away from the double-sided toothed plates (1022), and the other end of the reciprocating straight rod (1107) is penetrated by a driving gear (1108).

8. A timed and quantitative adding device for preparing raw materials of levofloxacin hydrochloride according to claim 7, characterized in that: The reciprocating push rod assembly (12) comprises a reciprocating slide (1201), the two ends of the reciprocating slide (1201) are respectively fixedly connected to opposite sides of two connecting plates (901), the side surface of the slideway of the reciprocating slide (1201) is slidably connected to an upper sliding gear rod (1202), the side of the upper sliding gear rod (1202) facing the reciprocating gear assembly (11) is fixedly connected to a reciprocating toothed belt (1203), and the inside of the reciprocating toothed belt (1203) is meshedly connected to the driving gear (110 8), the rack at the top of the upper sliding gear rod (1202) is meshedly connected with a push rod gear (1204), the push rod gear (1204) is axially connected to a reciprocating rotating rod (1205) at the axis center of the side away from the reciprocating gear assembly (11), one end of the reciprocating rotating rod (1205) is rotatably connected to a top wheel (1206), and the side surface of the shaft between the push rod gear (1204) and the reciprocating rotating rod (1205) is connected to the opposite side of the two connecting plates (901) through a sleeve rod.

9. A timed and quantitative adding device for preparing raw materials of levofloxacin hydrochloride according to claim 8, characterized in that: The discharge assembly (13) comprises an internal pressure spring (1301), one end of the internal pressure spring (1301) is fixedly connected to the inner side of the connecting plate (901), one end of the internal pressure spring (1301) is fixedly connected to an extrusion rod (1302), and the end of the extrusion rod (1302) facing the internal pressure spring (1301) is set as a trapezoidal structure, the other end of the extrusion rod (1302) is fixedly connected to a buckle plate (1303), and the inner side of the other end of the buckle plate (1303) is fixedly connected to a T-shaped pressure plate (1304), and the extrusion rod (1302) is fixedly connected to the inner side of the connecting plate (901). A lower ladder baffle (1305) is built on the side of the rod (1302) facing the inner pressure spring (1301), and a discharge top plate (1306) is fixedly connected to the top of the lower ladder baffle (1305), and the other end of the discharge top plate (1306) facing the lower ladder baffle (1305) is set as a semi-arc convex plate structure, and a baffle telescopic rod (1307) is fixedly connected to the upper surface of the discharge top plate (1306), and a baffle spring (1308) is fixedly connected to the opposite side of the discharge top plate (1306) and the baffle telescopic rod (1307).

10. A method for using a device for adding raw materials for preparing levofloxacin hydrochloride at a fixed time and fixed quantity according to claim 9, comprising the following steps: S1. First, levofloxacin and N-methylpiperazine are added to two material storage frames (3) respectively, and then the toothed disc (1001) on the side surface of the first double-rod tooth (1002) is rotated to adjust the pointing time of the toothed disc (1001) according to the addition ratio and the time for the levofloxacin to react with the catalyst first, so as to control the time for N-methylpiperazine to be discharged. The timing component (10) is triggered by the engagement of the secondary shaft (1014) with the stop sleeve (6). Then, the telescopic blocks (803) in the two lifting cards (201) are twisted according to the proportional weight to adjust the height of the reset quantitative component (8). Then, after the telescopic blocks (803) are twisted again to fix them, the conveying motor (107) is started to rotate the connected double-sided rotating wheel rods (106), and the remaining double-sided rotating wheel rods (106) are synchronously driven to rotate through the conveying toothed belt (108); S2, then push the two (5011) inward to drive the interlinked triangular straight rods (5010), so that the third slide bar (509) moves inward at one vertical end of the T rod (206), and in the process of the movement of the third slide bar (509), the double-rod shifting axis (508) on both sides are driven to slide at one horizontal end of the side slide bar (205), and at the same time, the two second slide bars (507) slide synchronously in the slideways at one end of the two side slide bars (205), and the two second slide bars (50 7) The first traction rod (506) on the side surface synchronously pulls the first abutment plates (504) at both ends of the baffle plate (502) to expand outward, and the two first slide bars (505) slide in the slideways at both ends of the interlayer outlet of the discharge port (4) to ensure that the first abutment plates (504) can slide in a directional manner. As the special-shaped slide blocks (501) in the two baffle plates (502) move in the interlayer of the discharge port (4) and leak out of the discharge port, the levofloxacin begins to fall into the hopper (709); S3. As more raw materials fall, the weight of the hopper (709) increases, and the concave plate (703) and the upper concave baffle (705) are pressed downward by the special-shaped flap (708) until the lower surface of the special-shaped flap (708) is pressed on the outer push rod (8010). Then, during the rotation of the outer push rod (8010), the upper shaft rod (805) on the same side is driven to rotate, and the rotation of the upper shaft rod (805) causes the T pressure rod (8011) and the rotating gear (8012) on the side surface to rotate. The rotating two upper shaft rods (805) cause the hook rod (809) and the outer push rod (8010) in the same direction to be pushed outward. The outer push rod (8010) pushed outward will simultaneously pull the bottom slide rod (807) below to slide on the slide groove vertical plate (804). At this time, the rotating rotating gear (8012) causes the traction gear below to rotate. The plate (8014) pulls open the flip top plate (8015) through the meshing teeth, so that (8016) is pushed upward, and the lifted (8016) causes the special-shaped flap (708) to be separated from the groove of the upper concave baffle (705), so that the special-shaped flap (708) is tilted upward. At the same time, the T-type pressure rod (8011) presses the lower pressure plate (7016) downward at the same time according to the angle problem, so that the hopper (709) is tilted. In the process of the hopper (709) falling, the outer push rod (8010) pushed outward by the force causes the two (5011) to be pulled outward, so that the baffle plate (502) can be automatically closed to prevent further material discharge. On the other hand, the flipped hopper (709) pours the raw materials into the upper surface of the conveyor toothed belt (108) to the slope of the discharge port (102), so that the raw materials and the catalyst are mixed in advance; S4. During the closing process, after the first abutment plate (504) moves inward and drives the anti-rotation sleeve rod (6) to separate from the side surface of the secondary shaft rod (1014), the rotating toothed disc (1001) is subjected to the torsion of the mainspring (1023), and the gear located on the inner side of the connecting plate (901) of the first double-rod teeth (1002) rotates, driving the special-shaped gear (1012) and the ratchet gear (1015) to rotate. Due to the one-way rack structure on the inner side of the ratchet gear (1015), the outer surface of the ratchet gear (1015) does not rotate, and The other gear of the first double-toothed bar (1002) drives the second double-toothed bar (1003), the third double-toothed bar (1004), the single-toothed rotating bar (1005) and the escapement gear (1006) to rotate. At this time, when the escapement gear (1006) is initially driven by the escapement bar (1007) to drive the balance wheel (1010) to rotate, the swinging hairspring (1011) subsequently reciprocates the upper fixed bar (1008) to move the escapement bar (1007) and the escapement gear (1006) back and forth. When the resistance is controlled, the gear plate (1006) is rotated. After the first double-rod gear (1002) rotates to the pointer position, the rotating first double-rod gear (1002) drives the special-shaped gear (1012) to rotate, and the rotating special-shaped gear (1012) causes the needle rod (1025) to move the protruding column (1026) and the firing wheel (1013) to rotate, thereby causing the ratchet gear (1015) to rotate in the opposite direction and causing the side surface of the ratchet gear (1015) to rotate the single-rotation gear rod (1016), and the rotating single-rotation gear rod (1016) causes the tension wheel (1017) to rotate, thereby pulling the tension belt ( 1018) and the triangular rod (1019) are lifted up, and the front half gear (1104) is rotated after being lifted up. The rotating front half gear (1104) makes the reciprocating middle gear (1103) and the rear half gear (1102) rotate synchronously, and the linkage gear (1105) ensures that the reciprocating middle gear (1103) and the rear half gear (1102) on the other side rotate synchronously. The rotating two rear half gears (1102) make the upper linkage gear (1106) and the reciprocating straight rod (1107) rotate, and finally the driving gear (1108) rotates; S5. As the tooth marks on the side surface of the driving gear (1108) mesh with the reciprocating toothed belt (1203), the upper sliding gear rod (1202) on one side of the reciprocating toothed belt (1203) slides on the slideway on the upper surface of the reciprocating slide seat (1201). The sliding upper sliding gear rod (1202) causes the top rod gear (1204) to rotate, thereby causing the reciprocating rotating rod (1205) and the top wheel (1206) to be lifted upward. During the lifting process, the top wheel (120 6) The discharge top plate (1306) and the lower ladder baffle plate (1305) are lifted up, and the internal pressure spring (1301) is forced to pull the extrusion rod (1302) and the buckle plate (1303), so that the T-shaped pressure plate (1304) is pressed down (5011), and the baffle plate (502) is driven to expand, so that N-methylpiperazine begins to be discharged. After reaching a corresponding weight, the discharge steps are repeated according to the levofloxacin unloading steps, and the discharge steps are reset under the pull of the corresponding spring.