A sample injection device for fully automatic chemiluminescence immunoassay analyzer

Abstract

The present invention discloses a sampling device for a fully automatic chemiluminescence immunoassay analyzer, comprising a sampling device body, wherein a buffer storage device is installed at the upper end of the sampling device body, and the buffer storage unit is added on the existing sampling unit by utilizing the height space of the instrument, so as to achieve real-time updating of test progress and temporary storage of tests that need to be automatically retested. After the sample rack is loaded into the sampling unit, a code scanning device scans and identifies the sample, and then the buffer unit loads the sample rack into the cache rack, at which time an estimated test completion time can be given, and the following processing can be performed according to whether automatic retesting is required. For test items that need automatic retesting, the sample rack needs to be transferred to the cache unit after sampling, and after the test results come out, it is guided to see whether retesting is required. If retesting is required, sampling is performed again, and then the sample rack enters an unloading area. For items that do not need automatic retesting, the sample rack directly enters the unloading area after sampling.

Description

Technical Field

[0001] The invention belongs to the technical field related to a sample injection device for a fully automatic chemiluminescence immunoassay analyzer, and in particular relates to a sample injection device for a fully automatic chemiluminescence immunoassay analyzer. Background Art

[0002] The sampling device of the fully automatic chemiluminescence immunoassay analyzer usually consists of a sample delivery system, a sample processing unit and an injection port. The device can automatically receive, process and transfer samples to ensure the accuracy and consistency of the samples during the analysis process. It can automatically identify the sample barcode, accurately locate the sample tube, and transfer the sample to the reaction module of the analyzer. The device supports a variety of sample types and has the characteristics of fast loading, automated operation and anti-pollution design, ensuring the accuracy of sample processing and the continuity of the experimental process, greatly improving laboratory testing efficiency.

[0003] The existing mainstream fully automatic chemiluminescence immunoassay stand-alone machines all need to meet the need to add samples at any time. Ideally, after the sample is added, the system will obtain the test requirements, calculate the required resources and allocate resources in a timely manner. The resources described here include reagent consumables, substrates and diluents. The system further needs to estimate the test completion time so that users can understand the test progress. In fact, the existing stand-alone injection is not comprehensive in meeting the above requirements. The fixed injection system represented by AE-180 can meet the requirements of real-time update of test progress after loading, but it cannot circulate the injection. Models represented by AE-240 and Antu A2000 cannot give real-time test progress at all and cannot perform automatic retesting. Summary of the invention

[0004] The purpose of the present invention is to provide a sample injection device for a fully automatic chemiluminescence immunoassay instrument, so as to solve the problem that the existing mainstream fully automatic chemiluminescence immunoassay stand-alone instruments mentioned in the above background technology need to meet the need to add samples at any time. Ideally, after the sample is added, the system will obtain the test requirements, calculate the required resources and allocate the resources in time. The resources described here include reagent consumables, substrates and diluents. Further, the system needs to estimate the test completion time so that the user can understand the test progress. In fact, the existing stand-alone sample injection is not comprehensive in meeting the above requirements. The fixed sample injection system represented by AE-180 can meet the requirement of real-time update of the test progress after loading, but it cannot cyclically inject samples. The models represented by AE-240 and Antu A2000 cannot give real-time test progress at all and cannot perform automatic retesting.

[0005] To achieve the above-mentioned object, the present invention provides the following technical solutions: a sample injection device for a fully automatic chemiluminescence immunoassay analyzer, comprising a sample injection device body, a buffer storage device is installed at the upper end of the sample injection device body, a Y-axis motion mechanism is installed at the upper end of the buffer storage device at the left and right sides, a sample cache storage bracket that can move forward and backward is installed at the upper end of the Y-axis motion mechanism, the sample cache storage bracket is driven to move by a motor A at the lower end, and a sample rack A is arranged at the upper end of the sample cache storage bracket; An X-axis motion mechanism is provided at the front end position of the buffer storage device, and a support frame is installed at the front end position of the buffer storage device through the X-axis motion mechanism. The support frame is driven to move by a motor C at the rear end position, and a Z-axis motion mechanism is installed at the upper front end position of the support frame. A sample rack gripper that can move up and down is installed at the front end position of the support frame through the Z-axis motion mechanism, and a motor B is installed at the upper end position of the sample rack gripper.

[0006] Preferably, a sampling mechanism is installed at the rear end of the sampling device body, a sample needle is installed at the front end of the sampling mechanism, and a barcode gun for scanning codes is provided at the rear end of the sampling device body.

[0007] Preferably, the sampling device body is connected to an external circuit for signal connection via a connection port at the front end.

[0008] Preferably, a motor D is installed at an upper position of the rear end of the sampling mechanism, and the motor D drives the output shaft at the upper end to rotate. The rotation of the output shaft causes the belt sleeved at the outer wall to rotate, and the other side of the belt is sleeved with a gear turntable. Since the gear turntable is connected to the sampling mechanism, the gear turntable drives the sampling mechanism to rotate.

[0009] Preferably, the rotation of the sampling mechanism drives the sample needle to rotate, so that the sample needle is adjusted to the upper position of the sample tube. A motor E is provided at the lower position of the rear end of the sampling mechanism. The motor E drives the chain at the front end position to rotate, and the movement of the chain causes the sampling mechanism to move up and down.

[0010] Preferably, the sampling mechanism can be moved downwards under the drive of the chain, so that the sample needle enters the inner position of the sample tube.

[0011] Preferably, the sample rack A is installed at the upper end of the sample cache storage bracket, and the support frame is driven by the motor C to move along the X-axis motion mechanism.

[0012] Preferably, the support frame moves the sample rack gripper to a position above the sample rack A, and the motor B drives the sample rack gripper to move downward, so that the sample rack gripper can grab the sample rack A.

[0013] Preferably, the upper right side of the main body of the sample injection device is an unloading area, and the barcode gun scans the barcode in the sample rack A.

[0014] Compared with the prior art, the present invention provides a sample injection device for a fully automatic chemiluminescence immunoassay analyzer, which has the following beneficial effects: A buffer storage unit is added on top of the existing sampling unit, utilizing the space at the height of the instrument, so as to achieve real-time updating of the test progress and temporary storage of tests that require automatic retesting. After the sample rack is loaded into the sampling unit, the code scanning device scans and identifies the sample, and then the buffer unit loads the sample rack into the cache rack. At this time, an estimated test completion time can be given. After the sample is sampled, the following processing can be performed based on whether automatic retesting is required. For test items that require automatic retesting, the sample rack needs to be transferred to the cache unit after sampling. After the test results come out, see if retesting is required. If retesting is required, sample again, and then the sample rack enters the unloading area. For items that do not require automatic retesting, they directly enter the unloading area after sampling. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] Figure 1 The present invention is a schematic structural diagram of a sample injection device for a fully automatic chemiluminescence immunoassay analyzer.

[0016] Figure 2 The present invention is a schematic diagram of the three-dimensional structure of a sample injection device for a fully automatic chemiluminescence immunoassay analyzer.

[0017] Figure 3 The present invention is a schematic diagram of the split structure of a sample injection device for a fully automatic chemiluminescence immunoassay analyzer.

[0018] Figure 4 The present invention is a schematic diagram of a top view of the structure of a sample injection device for a fully automatic chemiluminescence immunoassay analyzer.

[0019] In the figure: 1. Sample injection device body; 2. Buffer storage device; 3. Sample rack A; 4. Barcode gun; 5. Unloading area; 6. Sampling mechanism; 7. Sample needle; 8. Sample rack gripper; 9. X-axis motion mechanism; 10. Y-axis motion mechanism; 11. Z-axis motion mechanism; 12. Sample cache storage bracket; 13. Motor A; 14. Motor B; 15. Motor C; 16. Support frame; 17. Connection port; 18. Motor D; 19. Output shaft; 20. Belt; 21. Motor E; 22. Chain; 23. Gear turntable. DETAILED DESCRIPTION

[0020] The technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0021] In the description of the present invention, it should be noted that the terms "upper", "lower", "inner", "outer", "front end", "rear end", "two ends", "one end", "the other end" and the like indicate positions or positional relationships based on the positions or positional relationships shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first" and "second" are used for descriptive purposes only and cannot be understood as indicating or implying relative importance.

[0022] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "provided with", "connected", etc. should be understood in a broad sense. For example, "connected" can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be an indirect connection through an intermediate medium, or it can be the internal connection of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances. The invention provides Figure 1-4 The sample injection device for a fully automatic chemiluminescence immunoassay analyzer shown in the figure comprises a sample injection device body 1, a buffer storage device 2 is installed at the upper end position of the sample injection device body 1, a Y-axis motion mechanism 10 is installed at the upper end of the buffer storage device 2 at the left and right sides, a sample cache storage bracket 12 that can move forward and backward is installed at the upper end position of the Y-axis motion mechanism 10, the sample cache storage bracket 12 is driven to move by a motor A13 at the lower end position, a sample rack A3 is arranged at the upper end position of the sample cache storage bracket 12, an X-axis motion mechanism 9 is arranged at the front end position of the buffer storage device 2, a support frame 16 is installed at the front end position of the buffer storage device 2 through the X-axis motion mechanism 9, the support frame 16 is driven to move by a motor C15 at the rear end position, a Z-axis motion mechanism 11 is installed at the upper position of the front end of the support frame 16, a sample rack gripper 8 that can move up and down is installed at the front end position of the support frame 16 through the Z-axis motion mechanism 11, and a motor B14 is installed at the upper end position of the sample rack gripper 8.

[0023] The sample rack gripper 8 grabs the sample rack A3, and the barcode gun 4 scans the code to obtain sample information, including sample type, test items, etc. After the barcode gun 4 completes scanning, the sample rack A3 is placed at the upper end position of the sample cache storage bracket 12. The sample cache storage bracket 12 is driven by the motor A13 to move along the Y-axis motion mechanism 10 to move the sample rack A to the sampling area of ​​the sample needle 7. The motor D18 drives the sampling mechanism 6 to rotate and rotates the sample needle 7 to the upper position of the sample tube. At this time, the motor E21 starts the drive chain 22 to move, so that the sample needle 7 moves down into the sample tube for sampling. After sampling, the sample rack gripper 8 grabs the sample rack A3 and places it in the unloading area 5.

[0024] like Figure 1 and Figure 2 As shown, a sampling mechanism 6 is installed at the rear end position of the sampling device body 1, a sample needle 7 is installed at the front end position of the sampling mechanism 6, a barcode gun 4 for scanning codes is arranged at the rear end position of the sampling device body 1, and the sampling device body 1 is connected to the external circuit for signal through the connection port 17 at the front end position, and a motor D18 is installed at the upper position of the rear end of the sampling mechanism 6, and the motor D18 drives the output shaft 19 at the upper end position to rotate, and the rotation of the output shaft 19 causes the belt 20 sleeved at the outer wall position to rotate, and the other side of the belt 20 is sleeved with the gear turntable 23. Since the gear turntable 23 is connected to the sampling mechanism 6, the gear turntable 23 drives the sampling mechanism 6 to rotate, and the rotation of the sampling mechanism 6 drives the sample needle 7 to rotate, so that the sample needle 7 is adjusted to the upper position of the sample test tube, and a motor E21 is arranged at the lower position of the rear end of the sampling mechanism 6, and the motor E21 drives the chain 22 at the front end position to rotate, and the movement of the chain 22 causes the sampling mechanism 6 to move up and down.

[0025] A buffer storage unit is added on top of the existing sampling unit using the space at the instrument height, so as to achieve real-time updating of the test progress and temporary storage of tests that require automatic retesting. After the sample rack is loaded into the sampling unit, the code scanning device scans and identifies the sample, and then the buffer unit loads the sample rack into the cache rack. At this time, an estimated test completion time can be given. After the sample is sampled, the following processing can be performed based on whether automatic retesting is required. For test items that require automatic retesting, the sample rack needs to be transferred to the cache unit after sampling. After the test results come out, check whether retesting is required. If retesting is required, sample again, and then the sample rack enters the unloading area 5. For items that do not require automatic retesting, they directly enter the unloading area 5 after sampling.

[0026] like Figure 3 and Figure 4As shown, the sampling mechanism 6 can move downward under the drive of the chain 22, so that the sample needle 7 enters the internal position of the sample tube, and the sample rack A3 is installed at the upper end position of the sample cache storage bracket 12. The support frame 16 moves along the X-axis motion mechanism 9 under the drive of the motor C15. The support frame 16 moves the sample rack gripper 8 to the upper position of the sample rack A3. The motor B14 drives the sample rack gripper 8 to move downward, so that the sample rack gripper 8 can grab the sample rack A3. The upper right position of the sampling device body 1 is the unloading area 5, and the barcode gun 4 scans the barcode in the sample rack A3.

[0027] The buffer unit includes a sample cache storage bracket 12 that moves forward and backward along the Y axis, an X-axis motion mechanism 9, a Z-axis motion mechanism 11, and a sample rack gripper 8. The initial position is the rightmost side of the X axis, the highest point of the Z axis, and the manipulator is open. The sample rack grabbing position is the leftmost side of the X axis and the lowest point of the Z axis. The pre-cache storage position is the nearest end of the Y axis, and the buffer storage position is the farthest end of the Y axis. After the sample rack is scanned, if it is necessary to enter the buffer storage area, the X axis, Z axis and manipulator coordinate movement to grab the sample rack pre-cache storage position from the grabbing position, and the sample cache storage bracket 12 that moves forward and backward along the Y axis moves out, and the manipulator puts the sample rack into the slot of the bracket. After the work is completed, the X axis, Z axis and manipulator return to the initial position, and the Y axis returns to the cache storage position.

[0028] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer, characterized in that: The sample injection device comprises a main body (1), a buffer storage device (2) is installed at the upper end of the main body (1), a Y-axis motion mechanism (10) is installed at the upper end of the buffer storage device (2) at the left and right sides, a sample cache storage bracket (12) that can move forward and backward is installed at the upper end of the Y-axis motion mechanism (10), the sample cache storage bracket (12) is driven to move by a motor A (13) at the lower end, and a sample rack A (3) is arranged at the upper end of the sample cache storage bracket (12); An X-axis motion mechanism (9) is provided at the front end of the buffer storage device (2); a support frame (16) is installed at the front end of the buffer storage device (2) via the X-axis motion mechanism (9); the support frame (16) is driven to move by a motor C (15) at the rear end; a Z-axis motion mechanism (11) is installed at the upper front end of the support frame (16); a sample rack gripper (8) that can move up and down is installed at the front end of the support frame (16) via the Z-axis motion mechanism (11); a motor B (14) is installed at the upper end of the sample rack gripper (8).

2. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that: A sampling mechanism (6) is installed at the rear end of the sampling device body (1), a sample needle (7) is installed at the front end of the sampling mechanism (6), and a barcode gun (4) for scanning codes is provided at the rear end of the sampling device body (1).

3. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The sampling device body (1) is connected to an external circuit for signal connection via a connection port (17) at the front end.

4. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 2, characterized in that: A motor D (18) is installed at an upper position of the rear end of the sampling mechanism (6). The motor D (18) drives an output shaft (19) at an upper position to rotate. The rotation of the output shaft (19) causes a belt (20) sleeved at an outer wall position to rotate. The other side of the belt (20) is sleeved with a gear turntable (23). Since the gear turntable (23) is connected to the sampling mechanism (6), the gear turntable (23) drives the sampling mechanism (6) to rotate.

5. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 4, characterized in that: The rotation of the sampling mechanism (6) drives the sample needle (7) to rotate, so that the sample needle (7) is adjusted to a position above the sample tube. A motor E (21) is provided at a position below the rear end of the sampling mechanism (6). The motor E (21) drives the chain (22) at the front end to rotate. The movement of the chain (22) causes the sampling mechanism (6) to move up and down.

6. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 5, characterized in that: The sampling mechanism (6) can move downwards under the drive of the chain (22), so that the sample needle (7) enters the inner position of the sample test tube.

7. The sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The sample rack A (3) is installed at the upper end of the sample cache storage bracket (12), and the support frame (16) moves along the X-axis motion mechanism (9) under the drive of the motor C (15).

8. A sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 7, characterized in that: The support frame (16) moves the sample rack gripper (8) to a position above the sample rack A (3), and the motor B (14) drives the sample rack gripper (8) to move downward, so that the sample rack gripper (8) can grab the sample rack A (3).

9. The sample injection device for a fully automatic chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The upper right side of the sample injection device body (1) is an unloading area (5), and the barcode gun (4) scans the barcode in the sample rack A (3).

Images