Conditioning spray for controlling oil hair and preparation method thereof

Abstract

The invention relates to the field of hair cosmetic preparations, in particular to an oil-control hair conditioning spray and a preparation method thereof. The conditioning spray for controlling the oily hair is prepared from an HD I / trihydroxymethyl hexyl lactone cross-linked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, butanediol, polymethylsilsesquioxane and water. Meanwhile, a ginseng root extract and a fructus forsythiae extract are also added. The spray prepared by the invention can effectively nourish and moisten hair, has a better oil control effect, enables the hair to be fluffy and natural without whitening, is low in irritation and high in safety, and has an excellent scalp soothing effect.

Description

Technical Field

[0001] The invention relates to the field of hair cosmetic preparations, and in particular to an oil-controlling hair conditioning spray and a preparation method thereof. Background Art

[0002] Hair spray is a spray product for hair care. Its main function is to provide additional nutrition for hair and help repair hair damage, thereby effectively improving the health of hair. Common functions of hair spray include: 1. Prevent hair breakage and split ends: Hair nutrition and repair spray contains rich nutrients that can penetrate into the hair and repair the damaged parts of the hair, thereby preventing hair breakage and split ends. After using it for a period of time, the hair will become stronger and less prone to breakage and split ends; 2. Repair hair damage: The nutrients in the hair nutrition and repair spray can penetrate into the hair, replenish the nutrients needed by the hair, effectively repair the damaged areas of the hair, and make the hair healthier; 3. Increase hair gloss: The ingredients in the hair nutrition and repair spray can effectively increase the gloss of the hair, making the hair look more beautiful; 4. Increase hair softness: The ingredients in the hair nutrition and repair spray can effectively increase the softness of the hair and make the hair feel more comfortable.

[0003] However, after using hair spray for a few hours, chemical raw materials and environmental stimulation will increase the oil content in the scalp and hair, resulting in defects such as oily hair, hair collapse, and skin itching. Therefore, it is necessary to provide a hair spray that can provide basic hair nutrition effects while also providing the effects of inhibiting oily hair and hair collapse. This is a technical content that needs to be studied and a technical problem that needs to be solved. Summary of the invention

[0004] The present invention aims at the above technical problems and proposes a technical solution of the present invention. The technical solution of the present invention includes an oil-control hair conditioning spray and a preparation method thereof.

[0005] The invention provides a conditioning spray for oil-control hair, comprising: HDI / trimethylol hexyl lactone cross-linked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethyl pyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, butylene glycol, polymethyl silsesquioxane and water. Among them, HDI / trimethylol hexyl lactone cross-linked polymer, corn starch, distearyl dimethyl ammonium chloride and cyclodextrin can give the spray a film-forming type, produce shaping and fluffy hair effects, and also have the effect of absorbing oil; distearyl dimethyl ammonium chloride also has an antistatic effect, making the hair smooth. Tetrahydromethyl pyrimidine carboxylic acid has moisturizing, repairing, anti-aging and antioxidant effects. PCA zinc has the effects of oil control, moisturizing, antibacterial and anti-inflammatory, and also has excellent effects of promoting hair growth, enhancing hair health and gloss. Panthenol has moisturizing, anti-inflammatory and skin barrier repairing effects. Lauroyl lysine, as a softener and moisturizer, can effectively care for the scalp and hair. Caffeine can enhance the skin's ability to repair and improve dull skin. Butylene glycol has excellent moisturizing and scalp nourishing effects. Polymethylsilsesquioxane can effectively moisturize hair, making it smooth and not split.

[0006] Furthermore, the oil-control hair conditioning spray comprises, measured by mass percentage, 0.01-6% HDI / trimethylol hexyllactone cross-linked polymer, 0.01-3% corn starch, 0.005-1.0% distearyl dimethyl ammonium chloride, 0.00001-1.5% tetrahydromethylpyrimidine carboxylic acid, 0.0001-0.5% PCA zinc, 0.005-2.5% panthenol, 0.001-4% lauroyl lysine, 0.00001-1.5% caffeine, 0.00001-2% cyclodextrin, 0.001-10% butylene glycol, 1-3% polymethyl silsesquioxane and the balance water.

[0007] Furthermore, in order to effectively enhance the oil control and oil-suppressing effect of the spray and enhance the effect of the spray in nourishing hair, ginseng root extract and forsythia extract are added.

[0008] Furthermore, the invention further comprises 0.00001-3% of ginseng root extract and 0.00001-2.5% of forsythia suspensa extract.

[0009] Furthermore, the oil-control hair conditioning spray comprises, measured by mass percentage, 0.01-3% HDI / trimethylol hexyl lactone cross-linked polymer, 0.01-3% corn starch, 0.005-1.0% distearyl dimethyl ammonium chloride, 0.00001-0.5% tetrahydromethylpyrimidine carboxylic acid, 0.0001-0.5% PCA zinc, 0.005-1.0% panthenol, 0.001-3.0% lauroyl lysine, 0.00001-0.5% caffeine, 0.00001-0.5% cyclodextrin, 0.001-3.0% butylene glycol, 1-3% polymethyl silsesquioxane, 0.00001-0.5% ginseng root extract, 0.00001-0.5% forsythia extract and the balance water.

[0010] Furthermore, the oil-control hair conditioning spray comprises, measured by mass percentage, 3-6% HDI / trimethylol hexyllactone cross-linked polymer, 1-3% corn starch, 0.1-0.6% distearyl dimethyl ammonium chloride, 0.1-1.5% tetrahydromethylpyrimidine carboxylic acid, 0.01-0.3% PCA zinc, 0.5-2.5% panthenol, 1-4% lauroyl lysine, 0.5-1.5% caffeine, 0.5-2% cyclodextrin, 5-10% butylene glycol, 1-3% polymethyl silsesquioxane and the balance water.

[0011] Furthermore, 0.5-3% of ginseng root extract and 0.4-2.5% of forsythia suspensa extract are selected in the spray.

[0012] Furthermore, in order to optimize the spray oil control to inhibit oily hair and enhance the spray nourishing hair effect, the mass ratio of ginseng root extract to forsythia extract is 1:0.6-0.9.

[0013] Furthermore, the oil-control hair conditioning spray comprises, measured by mass percentage, 3-6% HDI / trimethylol hexyllactone cross-linked polymer, 1-3% corn starch, 0.1-0.6% distearyl dimethyl ammonium chloride, 0.1-1.5% tetrahydromethylpyrimidine carboxylic acid, 0.01-0.3% PCA zinc, 0.5-2.5% panthenol, 1-4% lauroyl lysine, 0.5-1.5% caffeine, 0.5-2% cyclodextrin, 5-10% butylene glycol, 1-3% polymethylsilsesquioxane, 0.5-3% ginseng root extract, 0.4-2.5% forsythia extract and the balance water.

[0014] Furthermore, the preparation method of ginseng root extract comprises the following steps:

[0015] Step 1: Take dried ginseng roots, crush them to obtain a product, add 8-30 times the mass of the product in water, boil and cool to obtain a cooling material;

[0016] Step 2: Add 800-1200U / mL of nattokinase and 800-1200U / mL of snail protease to the cooling material, raise the temperature to 35-55°C, stir and hydrolyze for 2-4.5 hours, inactivate the enzyme, cool and obtain the enzymolysis material;

[0017] Step 3: adding anhydrous ethanol to the enzymatic hydrolysis material to adjust the ethanol concentration to 20-35%, heating to 45-60° C. and stirring for 3-7 hours, filtering, and drying to obtain the ginseng root extract.

[0018] Furthermore, the preparation method of the Forsythia suspensa extract comprises the following steps:

[0019] S1: Take dried Forsythia suspensa leaves, crush them to obtain powder, add 10-35 times the weight of water, boil them and keep them at 60-80°C with stirring for 2-5 hours, cool them, and obtain liquid 1;

[0020] S2: Add 0.5-3.5% carbon source, 0.04-0.1% nitrogen source and fermentation bacteria to liquid 1, and ferment at 25-35°C with stirring for 150-400 hours to obtain liquid 2; the inoculation amount of the fermentation bacteria is (2.5-9)×10 9 cfu / g liquid 1, fermentation bacteria are composed of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 with a viable count of 1:1.5-2.5;

[0021] S3: sterilizing the liquid 2, filtering, and drying to obtain the Forsythia suspensa extract.

[0022] The present invention also provides a method for preparing the oil-control hair conditioning spray, which comprises the steps of mixing, sterilizing and packaging the raw materials.

[0023] The present invention also provides an oil-control hair conditioning spray product, comprising the oil-control hair conditioning spray and a spray bottle, wherein the spray bottle is loaded with the oil-control hair conditioning spray.

[0024] Beneficial effects of the present invention:

[0025] The HDI / trimethylol hexyl lactone cross-linked polymer, corn starch, distearyl dimethyl ammonium chloride and cyclodextrin in the raw materials of the present invention can give the spray a film-forming type, produce shaping and fluffy hair effects, and also have the effect of absorbing oil. Among them, distearyl dimethyl ammonium chloride also has an antistatic effect, making the hair soft. Tetrahydromethylpyrimidine carboxylic acid has moisturizing, repairing, anti-aging, antioxidant and oil control effects. PCA zinc has oil control, moisturizing, antibacterial and anti-inflammatory effects, and also has excellent effects of promoting hair growth, enhancing hair health and gloss. Panthenol has moisturizing, anti-inflammatory, skin barrier repair and oil control effects. Lauroyl lysine, as a softener and moisturizer, can effectively care for the scalp and hair. Caffeine can enhance the skin's repair ability and improve dull skin. Butylene glycol has excellent moisturizing and scalp moisturizing effects. Polymethyl silsesquioxane can effectively moisturize the hair, making the hair soft and not split. Added ginseng root extract and forsythia extract, it effectively enhances the spray's oil control, inhibits oily hair and enhances the spray's nourishing effect on hair.

[0026] The spray prepared by the present invention can effectively nourish and moisturize hair, has a good oil control effect, and makes the hair fluffy and natural without whitening. The spray prepared by the present invention has low irritation and high safety.

[0027] The spray prepared by the present invention has excellent effects of soothing the skin and inhibiting scalp itching and inflammation. At the same time, it can effectively inhibit 5α-reductase, effectively control the oiliness of the scalp and hair, inhibit the oily head phenomenon, and further avoid the collapse and dull whitening of hair.

[0028] The present invention adopts ginseng root extract and forsythia extract as spray raw materials, which can effectively improve the oil control and soothing effects of the spray.

[0029] The ginseng root extract and the forsythia extract used in the present invention form a compound relationship in the preparation system of the present invention, and the two synergistically enhance the oil control and soothing effects of the spray, and the ratio of the two is within the range of 1:0.6-0.9, and the obtained spray has a better effect.

[0030] The enzymatic hydrolysis process used in the present invention has an important influence on the effect of ginseng root extract, and the spray prepared by using nattokinase and snail protease for combined enzymatic hydrolysis of ginseng root extract has better effect than the spray prepared by enzymatic hydrolysis of only one of them.

[0031] The present invention adopts fermentation bacteria, Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849, to significantly improve the soothing and oil-control effects of Forsythia suspensa extract; the combined fermentation of the two can improve the soothing and oil-control effects of the spray more than other bacteria. The combined fermentation of the two has a better effect than fermentation with one of the bacteria, and the ratio of the bacteria is within the range of 1:1.5-2.5, and the prepared spray has a better effect.

[0032] The spray of the present invention has excellent effect and simple preparation process and has good application prospect. DETAILED DESCRIPTION

[0033] The present invention will be described below in conjunction with specific embodiments, and various effects of the present invention will be more clearly presented. It should be understood by those skilled in the art that these specific embodiments are used to illustrate the present invention, rather than to limit the present invention.

[0034] Aspergillus niger SHMCC D82829: Latin name: Aspergillus niger, purchased from Shanghai Baocang Microbiology Co., Ltd. Bacillus licheniformis SHMCC D24849: Latin name: Bacillus lichen iformi s, purchased from Shanghai Baocang Microbiology Co., Ltd. Bacillus subtilis ATCC 21332: Latin name: Bacillus subtilis (Ehrenberg) Cohn, purchased from Yanglaiyao Biotechnology Co., Ltd. - Standard Product Information Network. HDI / trimethylol hexyl lactone cross-linked polymer: Hubei Xinyuhong Biomedical Technology Co., Ltd. Corn starch: Guangzhou Xiaojia Chemical Technology Co., Ltd. Cyclodextrin: β-cyclodextrin, Wuhan Kemik Biomedical Technology Co., Ltd. Butanediol: 1,3-butanediol, Xi'an Tianzheng Pharmaceutical Excipients Co., Ltd. Panthenol: D-panthenol, Wuhan Kemik Biomedical Technology Co., Ltd. Polymethylsilsesquioxane: Guangzhou Batai New Material Technology Co., Ltd.

[0035] 1. Preparation of spray

[0036] 1. Spray 1:

[0037] Measured in percentage by mass, the raw materials include: 4.2% HDI / trimethylol hexyllactone crosslinked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane, 2.0% ginseng root extract and 1.7% forsythia extract and the balance water; the mass ratio of ginseng root extract to forsythia extract is 1:0.85.

[0038] Among them, ginseng root extract:

[0039] Step 1: Take dried ginseng roots, crush them to less than 50 meshes to obtain a product, add water 17.5 times the mass of the product, boil and cool to room temperature to obtain a cooling material;

[0040] Step 2: Add 1000U / mL nattokinase and 1000U / mL snail protease to the cooling material, heat to 47.5°C, stir at 60rpm for 3.5 hours, inactivate the enzyme, cool to room temperature, and obtain an enzymolysis material;

[0041] Step 3: adding anhydrous ethanol to the enzymatic hydrolyzate to adjust the ethanol concentration to 27.5%, heating to 50°C, stirring at 70rpm for 5.5 hours, filtering with a 0.22 micron pore size filter membrane, and freeze-drying the filtrate at -45°C to a water content of 1.65wt%, to obtain the ginseng root extract.

[0042] Preparation method of Forsythia suspensa extract:

[0043] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0044] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria consisted of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 in a ratio of 1:2;

[0045] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0046] The preparation method of the above-mentioned spray comprises: adding water and butylene glycol into a container, heating to 65°C, adding HDI / trimethylol hexyl lactone crosslinked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, polymethylsilsesquioxane, stirring at 100 rpm for 0.6 hour, cooling to 35°C, adding ginseng root extract and forsythia extract, keeping the speed unchanged and continuing to stir for 0.4 hour, then sterilizing and packaging to obtain the spray.

[0047] 2. Spray 2:

[0048] Measured in percentage by mass, the raw materials include: 4.0% HDI / trimethylol hexyllactone cross-linked polymer, 1.7% corn starch, 0.45% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 3% lauroyl lysine, 0.75% caffeine, 1.15% cyclodextrin, 9% butylene glycol, 2.5% polymethyl silsesquioxane, 2.4% ginseng root extract and 1.3% forsythia extract and the remainder water; the mass ratio of ginseng root extract to forsythia extract is 1:0.61.

[0049] Among them, ginseng root extract:

[0050] Step 1: Take dried ginseng roots, crush them to less than 50 meshes to obtain a product, add 20 times the mass of the product in water, boil and cool to room temperature to obtain a cooling material;

[0051] Step 2: Add 1200U / mL nattokinase and 800U / mL snail protease to the cooling material, heat to 48°C, stir at 60rpm for 3.8 hours, inactivate the enzyme, cool to room temperature, and obtain an enzymolysis material;

[0052] Step 3: adding anhydrous ethanol to the enzymatic hydrolyzate to adjust the ethanol concentration to 32%, heating to 52° C., stirring at 70 rpm for 6 hours, filtering with a 0.22 μm pore size filter membrane, and freeze-drying the filtrate at -45° C. to a water content of 1.62 wt %, to obtain the ginseng root extract.

[0053] Preparation method of Forsythia suspensa extract:

[0054] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 25 times the weight of water of the powder, boil it and keep it at 77°C, stir it at 65 rpm for 4.5 hours, and cool it to room temperature to obtain liquid 1;

[0055] S2: Add 3.2% carbon source, 0.08% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 280 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 7.05×10 9 cfu / g liquid 1, fermentation bacteria consisted of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 with a live cell count of 1:1.5;

[0056] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.87 wt%, to obtain the Forsythia suspensa extract.

[0057] The preparation method of the above-mentioned spray comprises: adding water and butylene glycol into a container, heating to 60°C, adding HDI / trimethylol hexyl lactone crosslinked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, polymethyl silsesquioxane, stirring at 100 rpm for 0.7 hour, cooling to 32°C, adding ginseng root extract and forsythia extract, keeping the speed unchanged and continuing to stir for 0.5 hour, then sterilizing and packaging to obtain the spray.

[0058] 3. Spray 3:

[0059] The raw materials include, measured by mass percentage, 4.2% HDI / trimethylol hexyl lactone cross-linked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane and the balance water;

[0060] The preparation method of the above-mentioned spray comprises: adding water and butylene glycol into a container, heating to 65° C., adding HDI / trimethylol hexyl lactone crosslinked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, polymethyl silsesquioxane, stirring at 100 rpm for 0.6 hour, cooling to 35° C., stirring for 0.4 hour while keeping the speed unchanged, and then sterilizing and packaging to obtain the spray.

[0061] 4. Spray 4:

[0062] Measured by mass percentage, the raw materials include: 4.2% HDI / trimethylol hexyl lactone crosslinked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane, 3.7% ginseng root extract and the balance water.

[0063] Among them, ginseng root extract:

[0064] Step 1: Take dried ginseng roots, crush them to less than 50 meshes to obtain a product, add water 17.5 times the mass of the product, boil and cool to room temperature to obtain a cooling material;

[0065] Step 2: Add 1000U / mL nattokinase and 1000U / mL snail protease to the cooling material, heat to 47.5°C, stir at 60rpm for 3.5 hours, inactivate the enzyme, cool to room temperature, and obtain an enzymolysis material;

[0066] Step 3: adding anhydrous ethanol to the enzymatic hydrolyzate to adjust the ethanol concentration to 27.5%, heating to 50°C, stirring at 70rpm for 5.5 hours, filtering with a 0.22 micron pore size filter membrane, and freeze-drying the filtrate at -45°C to a water content of 1.65wt%, to obtain the ginseng root extract.

[0067] The preparation method of the above-mentioned spray comprises: adding water and butylene glycol into a container, heating to 65°C, adding HDI / trimethylol hexyl lactone crosslinked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, polymethyl silsesquioxane, stirring at 100 rpm for 0.6 hour, cooling to 35°C, adding ginseng root extract, maintaining the speed unchanged and continuing to stir for 0.4 hour, then sterilizing and packaging to obtain the spray.

[0068] 5. Spray 5:

[0069] Measured in percentage by mass, the raw materials include: 4.2% HDI / trimethylol hexyl lactone cross-linked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane, 3.7% Forsythia suspensa extract and the balance water.

[0070] Preparation method of Forsythia suspensa extract:

[0071] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0072] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria consisted of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 in a ratio of 1:2;

[0073] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0074] The preparation method of the above-mentioned spray comprises: adding water and butylene glycol into a container, heating to 65°C, adding HDI / trimethylol hexyl lactone crosslinked polymer, corn starch, distearyl dimethyl ammonium chloride, tetrahydromethylpyrimidine carboxylic acid, PCA zinc, panthenol, lauroyl lysine, caffeine, cyclodextrin, polymethyl silsesquioxane, stirring at 100 rpm for 0.6 hour, cooling to 35°C, adding Forsythia suspensa extract, maintaining the speed unchanged and continuing to stir for 0.4 hour, then sterilizing and packaging to obtain the spray.

[0075] 6. Spray 6:

[0076] According to the mass percentage, the raw materials include: 4.2% HDI / trimethylol hexyl lactone cross-linked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane, 3% ginseng root extract and 0.7% forsythia extract and the balance water; the mass ratio of ginseng root extract to forsythia extract is 1:0.23. The rest is the same as that of spray 1.

[0077] 7. Spray 7:

[0078] According to the mass percentage, the raw materials include: 4.2% HDI / trimethylol hexyl lactone cross-linked polymer, 1.5% corn starch, 0.5% distearyl dimethyl ammonium chloride, 0.4% tetrahydromethylpyrimidine carboxylic acid, 0.1% PCA zinc, 2% panthenol, 2.8% lauroyl lysine, 0.8% caffeine, 1.2% cyclodextrin, 8.7% butylene glycol, 2.6% polymethyl silsesquioxane, 1.2% ginseng root extract and 2.5% forsythia extract and the balance water; the mass ratio of ginseng root extract to forsythia extract is 1:2.1. The rest is the same as that of spray 1.

[0079] 8. Spray 8:

[0080] The difference from spray 1 is only the process of ginseng root extract. The specific process is:

[0081] Step 1: Take dried ginseng roots, crush them to less than 50 meshes to obtain a product, add water 17.5 times the mass of the product, boil and cool to room temperature to obtain a cooling material;

[0082] Step 2: Add 2000U / mL nattokinase to the cooling material, raise the temperature to 47.5°C, stir at 60rpm for 3.5 hours, inactivate the enzyme, cool to room temperature, and obtain an enzymolysis material;

[0083] Step 3: adding anhydrous ethanol to the enzymatic hydrolyzate to adjust the ethanol concentration to 27.5%, heating to 50°C, stirring at 70rpm for 5.5 hours, filtering with a 0.22 micron pore size filter membrane, and freeze-drying the filtrate at -45°C to a water content of 1.65wt%, to obtain the ginseng root extract.

[0084] 9. Spray 9:

[0085] The difference from spray 1 is only the process of ginseng root extract. The specific process is:

[0086] Step 1: Take dried ginseng roots, crush them to less than 50 meshes to obtain a product, add water 17.5 times the mass of the product, boil and cool to room temperature to obtain a cooling material;

[0087] Step 2: add 2000U / mL snail protease to the cooling material, heat to 47.5°C, stir at 60rpm for 3.5 hours, inactivate the enzyme, cool to room temperature, and obtain the enzymolysis material;

[0088] Step 3: adding anhydrous ethanol to the enzymatic hydrolyzate to adjust the ethanol concentration to 27.5%, heating to 50°C, stirring at 70rpm for 5.5 hours, filtering with a 0.22 micron pore size filter membrane, and freeze-drying the filtrate at -45°C to a water content of 1.65wt%, to obtain the ginseng root extract.

[0089] 10. Spray 10:

[0090] The difference between this spray and spray 1 is only the process of making the forsythia extract. The specific process is:

[0091] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0092] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria is Aspergillus niger SHMCC D82829;

[0093] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0094] 11. Spray 11:

[0095] The difference between this spray and spray 1 is only the process of making the forsythia extract. The specific process is:

[0096] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0097] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria is Bacillus licheniformis SHMCC D24849;

[0098] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0099] 12. Spray 12:

[0100] The difference between this spray and spray 1 is only the process of making the forsythia extract. The specific process is:

[0101] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0102] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria consisted of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 with a live cell count of 1:0.5;

[0103] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0104] 13. Spray 13:

[0105] The difference between this spray and spray 1 is only the process of making the forsythia extract. The specific process is:

[0106] S1: Take dried Forsythia suspensa leaves, crush them to less than 50 meshes to obtain powder, add 20 times the weight of water of the powder, boil it and keep it at 75°C, stir it at 65 rpm for 4.2 hours, and cool it to room temperature to obtain liquid 1;

[0107] S2: Add 2.8% carbon source, 0.085% nitrogen source and fermentation bacteria to feed liquid 1, and perform aerobic fermentation at 30°C and 50 rpm for 320 hours to obtain feed liquid 2; the inoculation amount of fermentation bacteria is 6.90×10 9 cfu / g liquid 1, fermentation bacteria is Bacillus subtilis ATCC 21332;

[0108] S3: the feed solution 2 is sterilized, filtered through a 0.22 μm pore size filter membrane, and the filtrate is freeze-dried at -40°C to a water content of 1.92 wt%, to obtain the Forsythia suspensa extract.

[0109] 2. Application test of spray

[0110] The sprays 1-13 prepared above were subjected to performance tests.

[0111] 1. Patch test

[0112] The above-mentioned sprays 1-2 and 4-13 were prepared with PBS buffer (pH=7) to obtain 100 mg / mL samples. Volunteers with healthy skin aged 20-50 were selected and randomly divided into 13 groups, with 4 males and 4 females in each group. 0.05 mL of sample was taken into a spot tester and taped to the inside of the volunteer's arm to evenly apply the sample. Skin reactions were observed after 48 hours and evaluated according to the grades in Table 1. The test showed that the number of volunteers with negative skin reactions (grade 0) in the spray 1-2 and 4-13 groups was 8; it can be seen that the spray prepared by the present invention has low irritation and high safety.

[0113] Table 1: Skin reaction criteria

[0114]

[0115]

[0116] 2. Relief test

[0117] The TNF-α inhibition rate is used to indicate the strength of the spray's skin-soothing effect. The experimental principle is to select lipopolysaccharide LPS (bacterial endotoxin) to stimulate RAW264.7 macrophages, establish a cell inflammation model, then add different drugs to treat the cells, and compare the release levels of inflammatory factors in different cell groups; the specific experimental steps are as follows: inoculate RAW264.7 macrophages to a 12-well plate, incubate in an incubator at 37°C and 5% CO2 for 24 hours, add the above sprays to a mass concentration of 0.5%, add LPS to an LPS concentration of 1μg / mL 2 hours later, and stimulate for 24 hours as the experimental group; set up a model group without adding sprays, but adding LPS to an LPS concentration of 1μg / mL, and stimulating for 24 hours; set up a control group without adding LPS, but adding the above spray to a mass concentration of 0.5% for 26 hours. Then the supernatant was collected and centrifuged, and the ELISA kit was used to analyze the release level of the pro-inflammatory inflammatory factor TNF-α of RAW264.7, and the TNF-α inhibition rate of each experimental group was calculated. The calculation formula was: TNF-α inhibition rate = 100% × [(inflammatory factor concentration in the model group - inflammatory factor concentration in the experimental group) / (inflammatory factor concentration in the model group - inflammatory factor concentration in the control group)]. The test results are shown in Table 2.

[0118] Table 2: Relief Test

[0119]

[0120]

[0121] 3. Oil control effect test

[0122] The 5α-reductase inhibition rate is used to indicate the strength of the spray's oil control effect. The specific test method is: take the prostate of Kunming SD male rats, homogenize with water at a mass ratio of 1:5, centrifuge at 3000g for 10min, take the supernatant, and centrifuge at 10000g for 45min. The supernatant is the enzyme solution for testing. Experimental group: take 0.5g of the above spray, 0.7mL of enzyme solution and 0.1mL of 0.5mg / mL testosterone solution to react for 2.5 hours; blank group: use 0.7mL of enzyme solution and 0.1mL of 0.5mg / mL testosterone solution to react for 2.5 hours; after the reaction, measure the absorbance at 340nm and calculate the 5α-reductase inhibition rate. The calculation formula is: 5α-reductase inhibition rate = 100% × (blank group testosterone concentration change value - experimental group testosterone concentration change value) / blank group testosterone concentration change value. The test results are shown in Table 3.

[0123] Table 3: Oil control test

[0124]

[0125]

[0126] According to the tests in Table 2-3, the spray prepared by the present invention has excellent effects of soothing the skin and inhibiting scalp itching and inflammation. At the same time, it can effectively inhibit 5α-reductase, effectively control the oiliness of the scalp and hair, inhibit the oily head phenomenon, and further avoid the collapse and dull whitening of hair.

[0127] According to the test of sprays 1 and 3 in the table, the present invention uses ginseng root extract and forsythia extract as spray raw materials, which can effectively improve the oil control and soothing effects of the spray.

[0128] According to the test of sprays 4-7 in the table, it can be seen that ginseng root extract and forsythia extract form a compound relationship in the preparation system of the present invention, and the two synergistically enhance the oil control and soothing effects of the spray, and the ratio of the two is in the range of 1:0.6-0.9, and the obtained spray has a better effect.

[0129] According to the tests of sprays 1, 8-9 in the table, enzymatic hydrolysis has an important influence on the effect of ginseng root extract, and the spray prepared by combining enzymatic hydrolysis of nattokinase and snail protease has better effect than the one prepared by enzymatic hydrolysis alone.

[0130] According to the test of sprays 1, 10-12 in the table, fermentation with Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 can significantly improve the soothing and oil-control effects of Forsythia suspensa extract; the combined fermentation of the two can improve the soothing and oil-control effects of the spray more than other bacteria. The combined fermentation of the two has a better effect than fermentation with one of the bacteria, and the spray prepared in the range of 1:1.5-2.5 has a better effect.

[0131] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.

Claims

1. A conditioning spray for oil-control hair, characterized in that: include: HDI / Trimethylol Hexyllactone Crosspolymer, Corn Starch, Distearyldimonium Chloride, Tetrahydropyrimidine, Zinc PCA, Panthenol, Lauroyl Lysine, Caffeine, Cyclodextrin, Butylene Glycol, Polymethylsilsesquioxane, and Water.

2. The oil-control hair conditioning spray according to claim 1, characterized in that: The invention comprises, measured by mass percentage, 0.01-6% HDI / trimethylol hexyl lactone crosslinked polymer, 0.01-3% corn starch, 0.005-1.0% distearyl dimethyl ammonium chloride, 0.00001-1.5% tetrahydromethylpyrimidine carboxylic acid, 0.0001-0.5% PCA zinc, 0.005-2.5% panthenol, 0.001-4% lauroyl lysine, 0.00001-1.5% caffeine, 0.00001-2% cyclodextrin, 0.001-10% butylene glycol, 1-3% polymethyl silsesquioxane and the balance water.

3. The oil-control hair conditioning spray according to claim 1 or 2, characterized in that: According to the content in mass percentage, the invention also comprises 0.00001-3% of ginseng root extract and 0.00001-2.5% of forsythia suspensa extract.

4. The oil-control hair conditioning spray according to claim 3, characterized in that: The mass ratio of the ginseng root extract to the forsythia suspensa extract is 1:0.6-0.

9.

5. A method for preparing the oil-control hair conditioning spray according to any one of claims 1 to 4, characterized in that: It includes the steps of mixing, sterilizing and packaging the raw materials.

6. A hair conditioning spray product for oil control, characterized in that: The invention comprises the oil-control hair conditioning spray according to any one of claims 1 to 4 and a spray bottle, wherein the spray bottle is loaded with the oil-control hair conditioning spray.

7. The oil-control hair conditioning spray according to claim 4, the preparation method according to claim 5, or the oil-control hair conditioning spray product according to claim 6, characterized in that: The preparation method of ginseng root extract comprises the following steps: Step 1: Take dried ginseng roots, crush them to obtain a product, add 8-30 times the mass of the product in water, boil and cool to obtain a cooling material; Step 2: Add 800-1200U / mL of nattokinase and 800-1200U / mL of snail protease to the cooling material, raise the temperature to 35-55°C, stir and hydrolyze for 2-4.5 hours, inactivate the enzyme, cool and obtain the enzymolysis material; Step 3: adding anhydrous ethanol to the enzymatic hydrolysis material to adjust the ethanol concentration to 20-35%, heating to 45-60° C. and stirring for 3-7 hours, filtering, and drying to obtain the ginseng root extract.

8. The oil-control hair conditioning spray according to claim 4, the preparation method according to claim 5, or the oil-control hair conditioning spray product according to claim 6, characterized in that: The preparation method of the Forsythia suspensa extract comprises the following steps: S1: Take dried Forsythia suspensa leaves, crush them to obtain powder, add 10-35 times the weight of water, boil them and keep them at 60-80°C with stirring for 2-5 hours, cool them, and obtain liquid 1; S2: Add 0.5-3.5% carbon source, 0.04-0.1% nitrogen source and fermentation bacteria to liquid 1, and ferment at 25-35°C with stirring for 150-400 hours to obtain liquid 2; the inoculation amount of the fermentation bacteria is (2.5-9)×10 9 cfu / g liquid 1, fermentation bacteria are composed of Aspergillus niger SHMCC D82829 and Bacillus licheniformis SHMCC D24849 with a viable count of 1:1.5-2.5; S3: sterilizing the liquid 2, filtering, and drying to obtain the Forsythia suspensa extract.

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