Traditional Chinese medicine formula for treating vitiligo and preparation method

Abstract

The invention relates to the technical field of traditional Chinese medicine and pharmacy, and particularly discloses a traditional Chinese medicine formula for treating vitiligo and a preparation method. The medicinal liquor is prepared from the following raw materials in parts by weight: 10 to 25 parts of rhizoma seu radix notopterygii, 5 to 15 parts of rhizoma atractylodis macrocephalae, 5 to 15 parts of garter snake, 5 to 25 parts of rhizoma gastrodiae, 5 to 15 parts of semen cuscutae, 5 to 15 parts of radix bupleuri, 5 to 15 parts of radix ligustici sinensis, 5 to 15 parts of plum blossom, 5 to 15 parts of tribulus terrestris, 5 to 15 parts of tetrapanax papyriferus, 5 to 15 parts of lignum dalbergiae odoriferae, 5 to 15 parts of native copper, 10 to 25 parts of fructus psoraleae and 50 parts of pure grain liquor. The medicinal liquor infused with pure grain liquor has the efficacy of boosting by heating power, promoting blood circulation to remove blood stasis, improving microcirculation, improving blood and oxygen supply of a vitiligo affected part, promoting tyrosine synthesis, inhibiting melanin damage and preventing vitiligo from continuing to expand, and activates and repairs residual melanin cells by tonifying qi and activating blood, soothing liver and regulating qi and promoting melanin cell growth.

Description

Technical Field

[0001] The invention belongs to the technical field of traditional Chinese medicine, and particularly relates to a traditional Chinese medicine formula for treating vitiligo and a preparation method thereof. Background Art

[0002] Vitiligo is a common depigmented skin disease. With its long course, easy recurrence, and poor appearance, it has brought great troubles to the physical and mental health of patients. Traditionally, vitiligo has been treated with various methods, including drug therapy, phototherapy, and surgical treatment, but each method has limitations to varying degrees. As a treasure of the Chinese nation, traditional Chinese medicine has a long history and unique advantages in the treatment of vitiligo. In recent years, with the continuous deepening of the modernization of traditional Chinese medicine, more and more traditional Chinese medicine prescriptions have been discovered and applied to the treatment of vitiligo. These prescriptions are mostly based on tonifying the liver and kidneys, strengthening the spleen and stomach, dispelling wind and dampness, soothing the liver and regulating qi, and promoting blood circulation and removing blood stasis. They aim to achieve the purpose of treating vitiligo by regulating the internal environment of the human body.

[0003] However, although the existing traditional Chinese medicine treatment of vitiligo has achieved certain therapeutic effects, there are still traditional Chinese medicine prescriptions that often focus on the treatment of a certain aspect of the pathogenesis when treating vitiligo, while ignoring the complexity of the pathogenesis of vitiligo. The onset of vitiligo involves multiple aspects such as genetics, immunity, nerves, and endocrine. The treatment of a single pathogenesis is often difficult to achieve satisfactory results. In addition, the preparation process of the existing traditional Chinese medicine prescription is relatively simple, and water decoction or soaking method is mostly used to extract the effective ingredients in the medicinal materials. This preparation method is not only inefficient, but also difficult to ensure the full extraction of all effective ingredients in the medicinal materials. At the same time, the existing traditional Chinese medicine prescriptions also have certain inconveniences when used, such as multiple medication times, skin discomfort after application, etc., which affect the patient's medication experience and treatment effect, so staff need to improve it. Summary of the invention

[0004] The object of the present invention is to provide a Chinese medicine formula for treating vitiligo and a preparation method thereof, so as to solve the problems raised in the above-mentioned background technology.

[0005] To achieve the above object, the present invention provides the following technical solutions:

[0006] A traditional Chinese medicine formula for treating vitiligo comprises the following raw materials in parts by weight: 10 to 25 parts of Notopterygium wilfordii, 5 to 15 parts of Atractylodes macrocephala, 5 to 15 parts of Snakehead aconite, 5 to 15 parts of Gastrodia elata, 5 to 25 parts of Cuscuta chinensis, 5 to 15 parts of Bupleurum chinense, 5 to 15 parts of Ligusticum chuanxiong, 5 to 15 parts of Plum blossom, 5 to 15 parts of Tribulus terrestris, 5 to 15 parts of Tongcao, 5 to 15 parts of Dalbergia odorifera, 5 to 15 parts of Natural copper, 10 to 25 parts of Psoralea corylifolia and 50 parts of pure grain wine.

[0007] A method for preparing a traditional Chinese medicine prescription for treating vitiligo comprises the following steps:

[0008] Dry and crush the proportioned Notopterygium wilfordii, Atractylodes macrocephala, Snakehead aconite, Gastrodia elata, Cuscuta chinensis, Bupleurum chinense, Ligusticum chuanxiong, Prunus mume, Tribulus terrestris, Smilax glabra, Dalbergia odorifera and Psoralea corylifolia;

[0009] Put the crushed medicine powder into a pure cotton bag, and crush the natural copper into another small bag;

[0010] Soak the cloth bag containing the powder and the small bag containing the natural copper in 50 parts of pure grain wine;

[0011] After being soaked at room temperature for 180 days, an external medicinal wine for treating vitiligo is obtained.

[0012] Preferably, the concentration of the pure grain wine used to make the medicinal wine is 60°.

[0013] Preferably, the prepared medicinal wine is applied to the vitiligo affected area three times a day. The medicinal wine can be heated before application, and local hot compress treatment can be performed after application. One month is a treatment cycle, and generally six cycles can relieve or cure the disease.

[0014] Preferably, the medicinal wine is contraindicated for use by pregnant women, people with broken skin and people who are allergic to alcohol.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] (1) The medicinal liquor made from pure grain wine has a heat-boosting effect, which can invigorate blood circulation, improve microcirculation, increase blood and oxygen supply to vitiligo affected areas, promote tyrosine synthesis, inhibit melanin damage, and prevent vitiligo from continuing to spread.

[0017] (2) It promotes melanocyte growth and activates and repairs residual melanocytes by invigorating qi and activating blood circulation, soothing the liver and regulating qi.

[0018] (3) Through the penetration of thermal effect of drugs into the skin and mucous membranes, it can nourish the kidney and spleen, replenish the marrow and essence, relieve depression and calm the mind, play an overall regulatory role in balancing the nervous system, adjust the immune function, and prevent the recurrence of vitiligo after recovery. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1 The present invention is a flow chart of the method. DETAILED DESCRIPTION

[0020] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0021] Embodiment 1:

[0022] See also Figure 1 As shown, a traditional Chinese medicine formula for treating vitiligo is made up of the following raw materials in parts by weight: Notopterygium wilfordii: 10 to 25 parts, Atractylodes macrocephala: 5 to 15 parts, Snakehead aconite: 5 to 15 parts, Gastrodia elata: 5 to 25 parts, Cuscuta chinensis: 5 to 15 parts, Bupleurum chinense: 5 to 15 parts, Ligusticum chuanxiong: 5 to 15 parts, Plum blossom: 5 to 15 parts, Tribulus terrestris: 5 to 15 parts, Smilax glabra: 5 to 15 parts, Dalbergia odorifera: 5 to 15 parts, Natural copper: 5 to 15 parts, Psoralea corylifolia: 10 to 25 parts and 50 parts of pure grain wine.

[0023] The best composition is: 15 parts of Notopterygium wilfordii, 5 parts of Atractylodes macrocephala, 5 parts of Snakehead aconite, 10 parts of Gastrodia elata, 5 parts of Cuscuta australis, 5 parts of Bupleurum chinense, 10 parts of Ligusticum chuanxiong, 10 parts of Plum blossom, 5 parts of Tribulus terrestris, 5 parts of Tongcao, 5 parts of Dalbergia odorifera, 5 parts of Natural Copper, and 15 parts of Psoralea corylifolia.

[0024] A method for preparing a traditional Chinese medicine formula for treating vitiligo, comprising the following steps:

[0025] Dry and crush the proportion of Notopterygium wilfordii, Atractylodes macrocephala, Snakehead aconite, Gastrodia elata, Cuscuta chinensis, Bupleurum chinense, Ligusticum chuanxiong, Prunus mume, Tribulus terrestris, Smilax glabra, Dalbergia odorifera and Psoralea corylifolia;

[0026] Put the crushed medicine powder into a pure cotton bag, and crush the natural copper into another small bag;

[0027] Soak the cloth bag containing the powder and the small bag containing the natural copper in 50 parts of pure grain wine;

[0028] After being soaked at room temperature for 180 days, an external medicinal wine for treating vitiligo is obtained.

[0029] The concentration of pure grain wine used to make medicinal wine is 60°.

[0030] The prepared medicinal wine is applied to the vitiligo affected area three times a day. The medicinal wine can be heated before application, and local hot compress treatment can be performed after application. One month is a treatment cycle, and generally six cycles can provide relief or cure.

[0031] Medicinal liquor is contraindicated for use by pregnant women, people with broken skin, and those who are allergic to alcohol.

[0032] The drug principles of its formula are mostly from the aspects of nourishing the liver and kidney, strengthening the spleen and stomach, dispelling wind and dampness, soothing the liver and regulating qi, and promoting blood circulation and removing blood stasis. Dispelling wind should promote blood circulation, and blood circulation will eliminate wind. In the formula, Qianghuo, Sanleng, and Jiangxiang relieve the cold, dispel wind and overcome dampness, and promote blood circulation and remove blood stasis as the main medicine. In the formula, Cuscuta can promote melanocyte adhesion, Tribulus can induce melanocyte migration, nourish the liver and kidney, and the appearance is black when the kidney qi is sufficient. Psoralea can induce melanocyte adhesion and migration, can increase the skin's sensitivity to ultraviolet rays, increase the activity of tyrosinase in the epidermis, stimulate melanocytes to restore function, and regenerate melanin, which are all ministerial medicines. The spleen is the source of qi and blood biochemistry. Atractylodes can strengthen the spleen, which can make the qi and blood source sufficient and the skin prosperous, and is an adjuvant. Poria has the effects of promoting water and dampness, and strengthening the spleen, and is a guiding medicine. The combination of these medicines, with the help of the medicinal wine, can soothe the liver and regulate qi, promote blood circulation and remove blood stasis, dispel wind and evil, and nourish the liver and kidneys. It can be applied topically or smeared, so it can treat all types of vitiligo.

[0033] Implementation and application example 1, Yao Xgang, male, 66 years old, worked in the fields more than ten years ago, and his hands were bitten by insects and itchy. After scratching, scabs formed. After the scabs fell off, white patches appeared and then spread to the five fingers. He was diagnosed with vitiligo during treatment in the hospital. Although he was treated, the disease progressed and then developed to the ten toes of both feet. He applied this formula externally, combined with Ren and Du meridian acupoint plastering, and was cured after 9 months of treatment.

[0034] Implementation and application example 2: Zhang Xzhi, male, 75 years old, working as a teacher. Five years ago, he had itchy and scratched skin on his abdomen. White spots began to appear after the scabs fell off. Over a period of half a year, multiple white spots appeared on his abdomen without any pain or itching. He went to dermatology departments of several hospitals for treatment, but the disease could not be controlled. After applying this formula for half a year, the white spots on his abdomen no longer developed, and most of the spots have returned to their normal skin color.

[0035] Implementation and application example 3: Jin Xrong, female, 41 years old, developed vitiligo on the little finger of her right hand when she was 35 years old. Although she had been treated for several years, the effect was not obvious. After applying this formula locally, she was cured after one year.

[0036] After years of practice, it has been proved that the external vitiligo medicinal wine with this formula is an effective medicine for treating vitiligo.

[0037] This embodiment provides a specific and preferred raw material ratio, which is obtained after multiple experiments and has a better therapeutic effect.

[0038] Embodiment 2:

[0039] See also Figure 1As shown, a traditional Chinese medicine formula for treating vitiligo is made up of the following raw materials in parts by weight: Notopterygium wilfordii: 10 to 25 parts, Atractylodes macrocephala: 5 to 15 parts, Snakehead aconite: 5 to 15 parts, Gastrodia elata: 5 to 25 parts, Cuscuta chinensis: 5 to 15 parts, Bupleurum chinense: 5 to 15 parts, Ligusticum chuanxiong: 5 to 15 parts, Plum blossom: 5 to 15 parts, Tribulus terrestris: 5 to 15 parts, Smilax glabra: 5 to 15 parts, Dalbergia odorifera: 5 to 15 parts, Natural copper: 5 to 15 parts, Psoralea corylifolia: 10 to 25 parts and 50 parts of pure grain wine.

[0040] The best composition is: 15 parts of Notopterygium wilfordii, 5 parts of Atractylodes macrocephala, 5 parts of Snakehead aconite, 10 parts of Gastrodia elata, 5 parts of Cuscuta australis, 5 parts of Bupleurum chinense, 10 parts of Ligusticum chuanxiong, 10 parts of Plum blossom, 5 parts of Tribulus terrestris, 5 parts of Tongcao, 5 parts of Dalbergia odorifera, 5 parts of Natural Copper, and 15 parts of Psoralea corylifolia.

[0041] A method for preparing a traditional Chinese medicine prescription for treating vitiligo comprises the following steps:

[0042] Preparation of medicinal materials: Accurately weigh each medicinal material according to the ratio in Example 1, and perform preliminary cleaning to remove impurities on the surface of the medicinal materials.

[0043] Crushing and drying: Use appropriate crushing equipment to crush the medicinal materials into suitable sizes, and then dry them. The drying temperature should be controlled within a certain range to avoid the destruction of the active ingredients in the medicinal materials.

[0044] Bagging: Put the crushed powder into a pure cotton bag, and pay attention to evenly distribute the medicinal materials to avoid local accumulation. Natural copper has a hard texture, so it needs to be crushed separately and placed in another small bag to better release its active ingredients.

[0045] Soaking: Soak the cloth bag containing the medicine powder and the small bag containing natural copper in a 60° pure grain wine tank. Stir regularly during the soaking process to ensure that the medicine powder is in full contact with the wine.

[0046] Brewing time: Brew at room temperature for 180 days. During this period, pay attention to changes in the color and smell of the wine to prevent the medicinal wine from turning into a paste-like medicine.

[0047] Instructions for use: The prepared medicinal wine is applied to the affected area of ​​vitiligo three times a day. The medicinal wine can be heated appropriately before application to increase its permeability. After application, local hot compress treatment can be performed to promote the efficacy of the medicine. One month is a treatment cycle, and generally six cycles can relieve or cure the disease. At the same time, medicinal wine is contraindicated for pregnant women, people with skin ulcers, and those who are allergic to alcohol.

[0048] Embodiment three:

[0049] See also Figure 1 As shown, a preparation method of a traditional Chinese medicine formula for treating vitiligo is as follows:

[0050] First, the herbs such as Qianghuo, Baizhu, Wushe, Tianma, Cuscuta, Bupleurum, Ligusticum, Plum, Tribulus, Tongcao, Dalbergia, Natural Copper and Psoralea corylifolia are crushed and dried. The dried herbs are put into pure cotton bags to ensure that the herbs can fully release their active ingredients during the soaking process. At the same time, the natural copper is crushed separately and placed in another small bag. This is because the hardness of natural copper exceeds that of other herbs and it is easy to damage the knives of the crushing machine, so it needs to be handled separately.

[0051] Next, soak the cloth bag containing the medicinal powder and the small bag containing natural copper in a 60° pure grain wine tank. 60° pure grain wine was chosen as the soaking solvent because its moderate alcohol concentration helps to extract the active ingredients in the medicinal materials and maintain good stability.

[0052] After being brewed at room temperature for 180 days, the medicinal ingredients in the wine will be fully dissolved in the wine, forming an external wine with the effect of treating vitiligo. This wine can be applied to the affected area of ​​vitiligo three times a day. The wine can be heated before application to promote absorption, and local hot compress can be applied after application to enhance the efficacy. One month is a treatment cycle, and generally six cycles can relieve or cure the disease. However, it should be noted that pregnant women, people with skin ulcers, and people who are allergic to alcohol are prohibited from using this wine.

[0053] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A Chinese medicine formula for treating vitiligo, characterized in that: The invention comprises the following raw materials in parts by weight: 10 to 25 parts of Notopterygium wilfordii, 5 to 15 parts of Atractylodes macrocephala, 5 to 15 parts of Snakehead aconite, 5 to 15 parts of Gastrodia elata, 5 to 25 parts of Cuscuta australis, 5 to 15 parts of Bupleurum chinense, 5 to 15 parts of Ligusticum chuanxiong, 5 to 15 parts of Prunus mume, 5 to 15 parts of Tribulus terrestris, 5 to 15 parts of Tongcao, 5 to 15 parts of Dalbergia odorifera, 5 to 15 parts of natural copper, 10 to 25 parts of Psoralea corylifolia and 50 parts of pure grain wine.

2. A method for preparing a Chinese medicine formula for treating vitiligo, applicable to a Chinese medicine formula for treating vitiligo according to claim 1, characterized in that: The following steps are involved: Dry and crush the proportion of Notopterygium wilfordii, Atractylodes macrocephala, Snakehead aconite, Gastrodia elata, Cuscuta chinensis, Bupleurum chinense, Ligusticum chuanxiong, Prunus mume, Tribulus terrestris, Smilax glabra, Dalbergia odorifera and Psoralea corylifolia; Put the crushed medicine powder into a pure cotton bag, and crush the natural copper into another small bag; Soak the cloth bag containing the powder and the small bag containing the natural copper in 50 parts of pure grain wine; After being soaked at room temperature for 180 days, an external medicinal wine for treating vitiligo is obtained.

3. A method for preparing a Chinese medicine prescription for treating vitiligo according to claim 2, characterized in that: The concentration of the pure grain wine used to make the medicinal wine is 60°.

4. A method for preparing a Chinese medicine prescription for treating vitiligo according to claim 2, characterized in that: The prepared medicinal wine is used to apply to the vitiligo affected area three times a day. The medicinal wine can be heated before application, and local hot compress treatment can be performed after application. One month is a treatment cycle, and generally six cycles can relieve or cure the disease.

5. A method for preparing a Chinese medicine prescription for treating vitiligo according to claim 2, characterized in that: The above-mentioned medicinal wine is contraindicated for use by pregnant women, people with broken skin and those who are allergic to alcohol.

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