Assembled combined body component metabolism detection reagent card

Abstract

The invention discloses an assembled combined body component metabolism detection reagent card which comprises a reagent card base mechanism (A) and a plurality of solid-phase hole pieces (B), and the solid-phase hole pieces are fixedly arranged on the upper surface of the reagent card base mechanism in parallel at intervals through distance pieces. The detection reagent single cards are respectively used for bearing same or multiple different body component metabolism detection reagents; the solid-phase hole piece is in a concave hole shape and comprises a reagent solid-phase part (B1) and a solid-phase hole piece positioning handle (B2), and the reagent solid-phase part is arranged at the bottom of an inner hole, not communicated with the outside of the bottom, of the solid-phase hole piece and used for making a dry chemical reagent solid-phase at the bottom of the inner hole; the solid-phase hole piece positioning handle is arranged on one side edge of the solid-phase hole piece, extends outwards and is used for clamping and positioning the solid-phase hole piece through the base fixing groove when the reagent card is assembled; the reagent solid phase part comprises a solid phase hole (B11) and a reagent solid phase surface (B12); the reagent solid phase is on the reagent solid phase surface; the reagent card base mechanism comprises an assembly hole (A1) and a base fixing groove (A2).

Description

Technical Field

[0001] The invention relates to the technical field of dry chemical equipment, and in particular to an assembleable combined body composition metabolism detection reagent card. Background Art

[0002] Dry chemical analysis technology and detection methods are an important type of detection method in clinical testing. Dry chemical analysis technology is relative to wet chemical technology. It refers to adding liquid test samples directly to commercial dry reagent strips produced specifically for different projects, using the moisture of the sample to be tested as a solvent to cause a specific chemical reaction, thereby conducting chemical analysis. It is a type of analysis method based on enzyme method, also known as dry reagent chemistry or solid phase chemistry. Because dry chemical analysis technology and detection methods have the advantages of high accuracy, fast speed, and simple operation, they are widely used in various clinical project detection. Dry chemical reagents need to use a reagent device (hereinafter referred to as reagent card) as a carrier to solidify the reagent on the reagent card for easy use and transportation. At the same time, the reagent card also serves as a reaction carrier for dry chemical detection and plays an important role in dry chemical detection.

[0003] With the development of more and more dry chemical clinical projects, the application of multi-project joint detection is also increasing. Now the joint detection reagent cards on the market are generally designed as a fixed structure to meet the use requirements of specific projects. One reagent card can only be used for one joint detection project. For multiple joint detection projects, multiple different reagent cards are required, resulting in a large variety of dry chemical reagent cards, which are difficult to standardize, resulting in high reagent card costs and not conducive to the realization of instrument automated detection. Summary of the invention

[0004] The purpose of the present invention is to overcome the defects of the prior art and provide an assembleable combined body composition metabolism detection reagent card, which is applied to the body composition metabolism joint inspection project, can realize the free combination of reagent cards according to the number of indicators of the joint inspection project, and realize the standardization of the external dimensions of the reagent cards, so as to achieve the purpose of reducing costs and facilitating instrument automation.

[0005] The first aspect of the present invention is to provide an assembleable combined body composition metabolism detection reagent card, comprising: a reagent card base mechanism (A) and a plurality of solid-phase wells (B), wherein the plurality of solid-phase wells (B) are fixedly arranged in parallel and at intervals on the upper surface of the reagent card base mechanism (A) through spacers, and are respectively used to carry single detection reagent cards including the same or multiple different body composition metabolism detection reagents; the upper surfaces of the plurality of solid-phase wells (B) are flush with the upper surface of the reagent card base mechanism (A).

[0006] Preferably, the plurality of solid phase well elements (B) are evenly arranged at equal intervals on the upper surface of the reagent card base mechanism (A).

[0007] Preferably, the multiple solid phase hole elements (B) are evenly arranged on the upper surface of the reagent card base mechanism (A) in the form of fans or equally spaced rings, or are arranged on the upper surface of the reagent card base mechanism (A) in the form of equally spaced rectangles, semicircles, single circles or multiple circles.

[0008] Preferably, the plurality of solid phase hole components (B) are arranged on one side of the upper surface of the reagent card base mechanism (A) rather than in the center; or are arranged in the center of the upper surface of the reagent card base mechanism (A), and other components are arranged on both sides of the upper surface; or are arranged in two semicircular distributions on both sides of the upper surface of the reagent card base mechanism (A), and other components are arranged in the center of the reagent card base mechanism (A).

[0009] Preferably, the reagent card base mechanism (A) and the solid phase hole component (B) are made of plastic, ceramic, glass or inert high molecular polymer; the front side of the reagent card is defined from top to bottom. If the detection is performed from the front side of the reagent card, the reagent card base mechanism (A) and the solid phase hole component (B) are transparent or opaque materials; if the detection is performed from the back side of the reagent card, the reagent card base mechanism (A) and the solid phase hole component (B) are transparent materials.

[0010] Preferably, the solid phase hole component (B) is a concave hole, including a reagent solid phase portion (B1) and a solid phase hole component positioning handle (B2), wherein the reagent solid phase portion (B1) is arranged at the bottom of the inner hole of the solid phase hole component (B), the bottom of the inner hole is not in communication with the outside of the bottom, and the reagent solid phase portion (B1) is used to solidify the dry chemical reagent at the bottom of the inner hole; the solid phase hole component positioning handle (B2) is arranged on one side of the solid phase hole component (B) and extends outward, and is used to position the solid phase hole component (B) by engaging with the base fixing groove arranged at the corresponding position when the reagent card is assembled.

[0011] Preferably, the reagent solid phase part (B1) comprises a solid phase hole (B11) and a reagent solid phase surface (B12); the reagent solid phase is on the reagent solid phase surface (B12), and the solid phase hole (B11) is used to hold a liquid sample during reaction.

[0012] Preferably, the shape of the solid phase hole (B11) is circular, rectangular, square, elliptical or other irregular shapes.

[0013] Preferably, the reagent card base mechanism (A) comprises an assembly hole (A1) and a base fixing groove (A2); after the solid phase hole component (B) is placed into the assembly hole (A1), the solid phase hole component positioning handle (B2) is snapped into the base fixing groove (A2), thereby installing and positioning the solid phase hole component (B).

[0014] Preferably, the shape of the reagent card base mechanism (A) is circular, rectangular or square.

[0015] The second aspect of the present invention is to provide the application of the assembled combined body composition metabolism detection reagent card of the first aspect in non-dry chemical body composition metabolism joint detection projects and dry chemical body composition metabolism joint detection projects.

[0016] Beneficial effects of the assembled combined body composition metabolism detection reagent card of the present invention and its application:

[0017] (1) The combined assembly design reduces the types of reagent cards for dry chemical joint inspection items, realizes production standardization, and is conducive to promoting the automation of dry chemical instrument joint inspection;

[0018] (2) The modular design can be increased or decreased according to the needs of the dry chemical joint inspection items. It has a simple structure, is easy to assemble, has good flexibility, reduces material waste, and is conducive to reducing manufacturing costs. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] In order to more clearly illustrate the specific embodiments of the present invention or the technical solutions in the related technologies, the drawings required for use in the specific embodiments or the related technical descriptions will be briefly introduced below. Obviously, the drawings described below are some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0020] Figure 1 A schematic diagram of the structure of a combined reagent card provided according to an embodiment of the present invention;

[0021] Figure 2 A schematic diagram of a solid phase hole structure provided according to an embodiment of the present invention;

[0022] Figure 3 A cross-sectional view of the solid phase structure of a reagent provided according to an embodiment of the present invention;

[0023] Figure 4 A schematic diagram of a base structure provided according to an embodiment of the present invention;

[0024] Figure 5 A schematic diagram of an exploded structure of a combined reagent card assembly according to an embodiment of the present invention;

[0025] Figure 6 A schematic diagram of an exemplary structure of a three-item joint test assembly reagent card provided according to an embodiment of the present invention;

[0026] Figure 7 A schematic diagram of an exemplary structure of a five-item joint test assembly reagent card provided according to an embodiment of the present invention;

[0027] Figure 8A schematic diagram of a modified design structure of a single-circle ten-hole assembly reagent card according to an embodiment of the present invention;

[0028] Fig. 9 Schematic diagram of the structure of a double-circle twelve-hole reagent card provided according to an embodiment of the present invention. DETAILED DESCRIPTION

[0029] The technical solution of the present invention will be described clearly and completely below in conjunction with the accompanying drawings. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0030] In the description of the present invention, it should be noted that the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the drawings, and are only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as limiting the present invention. In addition, the terms "first", "second", and "third" are used for descriptive purposes only, and cannot be understood as indicating or implying relative importance.

[0031] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0032] Embodiment 1

[0033] like Figure 1 As shown, this embodiment provides an assembleable combined body composition metabolism detection reagent card, comprising: a base (A) and a plurality of solid-phase wells (B), wherein the plurality of solid-phase wells (B) are fixedly arranged on the upper surface of the base (A) in parallel and at intervals through spacers, and are respectively used to carry single detection reagent cards comprising the same or multiple different body composition metabolism detection reagents; the upper surfaces of the plurality of solid-phase wells (B) are flush with the upper surface of the base (A).

[0034] As a preferred embodiment, the plurality of solid phase hole elements (B) are uniformly arranged on the upper surface of the base (A) at equal intervals.

[0035] In the present embodiment, a plurality of solid-phase wells (B) are fan-shaped and evenly arranged on the upper surface of the base (A) in the form of equally spaced rings and arranged on one side of the upper surface rather than in the middle, so as to facilitate the arrangement of other components in the portion where the solid-phase wells are not arranged. A total of 6 solid-phase wells are arranged, respectively marked with numbers 1-6, to improve the compactness of the entire assembled combined body composition metabolism detection reagent card, and facilitate miniaturized production. Of course, those skilled in the art should know that it is also possible to arrange it in the form of equally spaced rectangles or semicircles, or to arrange it in the middle of the upper surface, and arrange other components on both sides of the upper surface. At the same time, it is also possible to arrange two semicircles on both sides of the upper surface, and arrange other components in the middle, all within the scope of protection of the present invention.

[0036] As a preferred embodiment, the base A and the solid phase hole piece B are made of plastic, ceramic, glass or inert polymer. This embodiment uses transparent acrylic, and the bottom light transmittance of the solid phase hole piece B is required to be above 95%. According to the actual needs of the detection equipment and the detection reagent project, the combination reagent card can be tested from the front or back. For detection from the front, the reagent card can be made of opaque materials, such as Figure 1 As shown in the figure, the front side of the reagent card is defined as the top to the bottom, and the back side is the reverse side. If the reagent card material must be transparent when testing from the back side, and there is no transparency requirement for testing from the front side, the reagent card material selection can be flexibly selected from plastic, ceramic, glass or inert polymer according to the specific reagent items and equipment testing requirements.

[0037] See the schematic diagram of the solid phase hole structure for details. Figure 2 .

[0038] As a preferred embodiment, the solid phase hole component B is a concave hole, including a reagent solid phase portion B1 and a solid phase hole component positioning handle B2, wherein the reagent solid phase portion B1 is arranged at the bottom of the inner hole of the solid phase hole component B, and the bottom of the inner hole is not in communication with the outside of the bottom, and the reagent solid phase portion B1 is used to solidify the dry chemical reagent at the bottom of the inner hole, such as Figure 2 The solid phase well component positioning handle B2 is arranged on one side of the solid phase well component B and extends outwards, and is used for positioning the solid phase well component B by engaging with the base fixing groove arranged at the corresponding position when the reagent card is assembled.

[0039] For example, see Figure 3In the cross-sectional view, the reagent solid phase portion B1 includes a solid phase hole (B11) and a reagent solid phase surface (B12); the reagent solid phase is on the reagent solid phase surface (B12), and the solid phase hole (B11) is used to hold the liquid sample during the reaction. The shape of the solid phase hole (B11) is a circular example. Those skilled in the art should know that the actual implementation is not limited to a circle, and can also be a rectangle, square, ellipse or other irregular shapes, all within the scope of protection of the present invention.

[0040] See also Figure 4 The schematic diagram of the reagent card base mechanism A shown in the figure, the reagent card base mechanism A is an example of a rectangle, and the reagent card base mechanism A includes an assembly hole A1 and a base fixing groove A2, which are the main functional features of the base. The solid phase hole component B is placed in the assembly hole A1 according to the direction shown in the figure, and the solid phase hole component positioning handle B2 is inserted into the base fixing groove A2 to achieve the installation and positioning of the solid phase hole component B. There are 6 assembly holes designed on the example base, and they are numbered 1-6 in a counterclockwise direction for hole position distinction, such as Figure 5 As shown, in actual use, the reagent card is assembled as needed according to the number of indicators of the joint inspection items. There is no requirement for the order of assembly holes, which can be flexibly determined according to usage requirements.

[0041] The combined reagent card can be freely combined, arranged and assembled according to the number of indicators of the joint inspection items, so as to realize the universal standardization of reagent card devices for different joint inspection items, reduce the types of reagent cards, and further reduce the types of molds, thus greatly reducing the processing cost.

[0042] This reagent card example uses a 6-index combination, but the number of combination wells in this scheme is not limited to 6, and can be increased or reduced according to the number of joint test indicators;

[0043] The preferred embodiments of the reagent card base mechanism A and the solid phase well member B are rectangular and fan-shaped structures. The present invention is not limited to this shape and can be modified and designed into other shapes for combination according to actual needs. For example:

[0044] like Figure 6 Shown is a schematic diagram of an example structure of a three-item joint test assembly reagent card, which has three holes (three holes are vacant), a fan-shaped solid phase hole component and a rectangular reagent card base mechanism A.

[0045] like Figure 7 Shown is a schematic diagram of an example structure of a five-item joint test assembly reagent card, which has five holes (one hole is vacant), a fan-shaped solid phase hole component and a rectangular reagent card base mechanism A.

[0046] like Figure 8 Shown is a schematic diagram of a modified design structure of a single-circle ten-hole assembled reagent card, which has ten holes in a single-circle layout design, a circular structure solid phase hole part and a circular reagent card base mechanism A.

[0047] like Fig. 9 Shown is a schematic diagram of a double-circle twelve-well reagent card structure, which has twelve wells with a double-circle layout design, a circular structure solid phase well piece and a circular reagent card base mechanism A.

[0048] Embodiment 2

[0049] This embodiment provides the application of the assembled combined body composition metabolism detection reagent card of the first embodiment in non-dry chemical body composition metabolism joint detection projects and dry chemical body composition metabolism joint detection projects.

[0050] Through the description of the above implementation methods, those skilled in the art can clearly understand that the above embodiments can be implemented by software, or by means of software plus necessary general hardware platforms. Based on such understanding, the technical solutions of the above embodiments can be embodied in the form of software products, which can be stored in a non-volatile storage medium (which can be an AD-ROM, a USB flash drive, a mobile hard disk, etc.), including several instructions for enabling a computer device (which can be a personal computer, a server, or a network device, etc.) to execute the methods described in the various embodiments of the present invention.

[0051] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. An assembleable body composition metabolism detection reagent card, characterized in that: include: A reagent card base mechanism (A) and a plurality of solid-phase well components (B), wherein the plurality of solid-phase well components (B) are fixedly arranged in parallel and at intervals on the upper surface of the reagent card base mechanism (A) through spacers, and are respectively used to carry single detection reagent cards including the same or multiple different body component metabolism detection reagents; the upper surfaces of the plurality of solid-phase well components (B) are flush with the upper surface of the reagent card base mechanism (A).

2. The assembleable body composition metabolism detection reagent card according to claim 1, characterized in that: The plurality of solid phase wells (B) are evenly arranged at equal intervals on the upper surface of the reagent card base mechanism (A).

3. The assembleable body composition metabolism detection reagent card according to claim 2, characterized in that: The multiple solid phase hole elements (B) are evenly arranged on the upper surface of the reagent card base mechanism (A) in the form of fans or equally spaced rings, or in the form of equally spaced rectangles, semicircles, single circles or multiple circles.

4. The assembleable body composition metabolism detection reagent card according to claim 3, characterized in that: The multiple solid phase hole components (B) are arranged on one side of the upper surface of the reagent card base mechanism (A) instead of in the middle; or are arranged in the middle of the upper surface of the reagent card base mechanism (A), and other components are arranged on both sides of the upper surface; or are arranged in two semicircular distributions on both sides of the upper surface of the reagent card base mechanism (A), and other components are arranged in the middle of the reagent card base mechanism (A).

5. The assembleable body composition metabolism detection reagent card according to claim 4, characterized in that: The reagent card base mechanism (A) and the solid phase hole component (B) are made of plastic, ceramic, glass or inert high molecular polymer; the front side of the reagent card is defined from top to bottom. If the test is performed from the front side of the reagent card, the reagent card base mechanism (A) and the solid phase hole component (B) are made of transparent or opaque materials; if the test is performed from the back side of the reagent card, the reagent card base mechanism (A) and the solid phase hole component (B) are made of transparent materials.

6. The assembleable body composition metabolism detection reagent card according to claim 5, characterized in that: The solid phase hole component (B) is in the shape of a concave hole, and includes a reagent solid phase portion (B1) and a solid phase hole component positioning handle (B2), wherein the reagent solid phase portion (B1) is arranged at the bottom of the inner hole of the solid phase hole component (B), and the bottom of the inner hole is not in communication with the outside of the bottom, and the reagent solid phase portion (B1) is used to solidify the dry chemical reagent at the bottom of the inner hole; the solid phase hole component positioning handle (B2) is arranged on one side of the solid phase hole component (B) and extends outward, and is used to position the solid phase hole component (B) by engaging with the base fixing groove arranged at the corresponding position when the reagent card is assembled.

7. The assembleable body composition metabolism detection reagent card according to claim 6, characterized in that: The reagent solid phase part (B1) comprises a solid phase hole (B11) and a reagent solid phase surface (B12); the reagent solid phase is on the reagent solid phase surface (B12), and the solid phase hole (B11) is used to hold a liquid sample during reaction.

8. The assembleable body composition metabolism detection reagent card according to claim 7, characterized in that: The shape of the solid phase hole (B11) is circular, rectangular, square, elliptical or other irregular shapes.

9. The assembleable body composition metabolism detection reagent card according to claim 8, characterized in that: The reagent card base mechanism (A) comprises an assembly hole (A1) and a base fixing groove (A2); after the solid phase hole component (B) is placed in the assembly hole (A1), the solid phase hole component positioning handle (B2) is inserted into the base fixing groove (A2), thereby installing and positioning the solid phase hole component (B).

10. The assembleable body composition metabolism detection reagent card according to claim 9, characterized in that: The shape of the reagent card base mechanism (A) is circular, rectangular or square.

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