Mass spectrometer sampling device, control method, storage medium and electronic equipment

Abstract

The invention discloses a mass spectrometer sampling device, a control method, a storage medium and electronic equipment. The mass spectrometer sampling device comprises a loading table; the material carrying table is provided with a supporting piece and an adjusting assembly. The adjusting assembly comprises a plurality of connecting pieces, any connecting piece is in sliding connection with the supporting piece and moves in the arrangement direction of the supporting piece, and the connecting pieces are sequentially and rotationally connected; a pipetting mechanism is arranged below the connecting piece far away from one side of the supporting piece, and is matched with the sampling needle; a needle taking clamping block is further arranged on the material carrying table, the liquid transferring mechanism drives the sampling needle to move to the needle taking clamping block, and the sampling needle is separated from the liquid transferring mechanism; the sample introduction coordinate is flexible, the pipetting mechanism can be dragged to position the sample introduction position and set the current sample introduction position, repeated debugging through coordinate input is not needed, the layout can be moved according to needs, the compact experiment space is not occupied, and the applicability is better.

Description

Technical Field

[0001] The present invention relates to the field of mass spectrometry sampling detection, and in particular to a mass spectrometer sampling device, a control method, a storage medium and an electronic device. Background Art

[0002] There are currently two types of mass spectrometry automatic injection systems in the existing technology. One is the liquid phase built-in injection system, which must be used in conjunction with a liquid-mass spectrometer or a closed ion source mass spectrometer, which greatly limits its application in other types of mass spectrometers. For example, open mass spectrometer ion sources and new mass spectrometer ion sources cannot use this injection system. This means that in research or analysis work, if these special types of mass spectrometer ion sources are involved, it is necessary to find other injection methods, which increases the complexity and cost of experimental settings.

[0003] The other type is an external XYZ-axis injection system. The system is limited in its movement in the XYZ-axis direction, which means that it lacks flexibility in acquiring samples. It may not be able to accurately reach samples in some special locations, or when samples in multiple different locations need to be injected quickly and continuously, the task cannot be completed efficiently due to the limited range of movement, affecting the efficiency of the experiment. The number of sample plate positions is limited, so the number of samples that can be placed for analysis at one time is small, and the sample plates need to be replaced frequently, increasing the workload and time cost of manual operation. At the same time, it occupies a large space and has strict requirements on the installation site and laboratory space. Summary of the invention

[0004] The purpose of the present invention is to solve the shortcomings of the prior art and to propose a mass spectrometer sampling device, a control method, a storage medium and an electronic device.

[0005] In order to achieve the above object, the present invention adopts the following technical solution: a mass spectrometer sampling device, comprising:

[0006] Loading table;

[0007] The loading table is provided with a support member and an adjustment component;

[0008] The adjustment assembly includes a plurality of connecting members, any of which is slidably connected to the support member and moves along the setting direction of the support member, and a plurality of the connecting members are rotatably connected in sequence;

[0009] A liquid transfer mechanism is provided below the connecting member on one side away from the supporting member, and the liquid transfer mechanism cooperates with the sampling needle;

[0010] The loading table is also provided with a needle retrieval block, and the pipetting mechanism drives the sampling needle to move to the needle retrieval block to separate the sampling needle from the pipetting mechanism.

[0011] As a further description of the above technical solution: a groove is provided on the loading table, a needle holder, a first sample plate holder and a second sample plate holder are placed inside the groove, a cover plate is provided on the first sample plate holder, and a holder pressure ring is provided on one side of the groove.

[0012] As a further description of the above technical solution: a plurality of sampling needles are placed inside the needle holder, and the pipetting mechanism is moved to the sampling needles through the adjusting assembly and moves downward to cooperate with the sampling needles.

[0013] As a further description of the above technical solution: a slide groove is set on the support member, one end of the connecting member is installed on the slide groove and moves along the setting direction of the slide groove, the other side of the connecting member is connected to another connecting member through a rotating shaft, and the rotating shaft is driven to rotate by a motor.

[0014] As a further description of the above technical solution: a recovery box is also arranged on the loading table, and the recovery box is arranged below the needle removal block.

[0015] Also included is a control method, which is applicable to the sample injection device according to any one of the above technical solutions, including:

[0016] S1: Obtain the position information of the origin, the pipetting mechanism, the needle holder, the first sample plate holder, the second sample plate holder and the injection, and perform collision detection.

[0017] S2: Determine whether there is a sampling needle at the pipetting mechanism. If yes, return to the origin to remove the sampling needle. If no, control the pipetting mechanism to move to the needle holder.

[0018] S3: Control the support and the adjustment component to move, drive the pipetting mechanism to press down and install the sampling needle, move to the first sample holder or the second sample holder to take samples, and after completion, move up and out of the sampling needle to hover;

[0019] S4: Control the pipetting mechanism to move to the injection position, discharge the liquid, and move out of the injection position after standing still, and return to step S2.

[0020] As a further description of the above technical solution: the collision detection includes:

[0021] S11: setting the origin position, dragging the pipetting mechanism to the needle support, the first sample plate support, the second sample plate support and the injection position, and saving the position information;

[0022] S12: Control the sample injection process to test run and detect whether a collision occurs. If yes, control the pipetting mechanism to save at the current position point, add position compensation information, and perform position calibration. If no, control the pipetting mechanism to return to the origin position.

[0023] As a further description of the above technical solution: returning to the origin to remove the sampling needle includes: controlling the pipetting mechanism to move to the origin, the origin is below the needle removal block, and after reaching the origin, controlling the pipetting mechanism to move upward to remove the sampling needle.

[0024] It also includes a computer-readable storage medium storing a computer program for running the control method, wherein the computer program enables a computer to execute the control method as described in any one of the above technical solutions.

[0025] Also included is an electronic device, comprising:

[0026] one or more processors; memory; and

[0027] One or more programs, wherein the one or more programs are stored in the memory and are configured to be executed by the one or more processors, and the programs include a control method for executing any one of the above technical solutions.

[0028] The above technical solution has the following advantages or beneficial effects:

[0029] 1. The injection coordinates are flexible. The pipetting mechanism can be dragged to locate the injection position and set the current injection position. There is no need to repeatedly debug through coordinate input. The layout can be moved as needed, which does not occupy the compact experimental space and has better applicability.

[0030] 2. The sample plate can be set up flexibly and can hold a large number of samples. Samples stored in different containers can be tested by simply replacing the sample plate holder. Large batches of samples can also be processed at one time, with a maximum of 384 pieces * 2 groups. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 A front view of the mass spectrometer injection device provided by the present invention;

[0032] Figure 2 A top view of the mass spectrometer injection device proposed by the present invention;

[0033] Figure 3 The three-dimensional mass spectrometer injection device proposed by the present invention Figure 1 ;

[0034] Figure 4 The three-dimensional mass spectrometer injection device proposed by the present invention Figure 2 ;

[0035] Figure 5 The three-dimensional mass spectrometer injection device proposed by the present invention Figure 3 ;

[0036] Figure 6 The process of the control method proposed by the present invention is Figure 1 ;

[0037] Figure 7 The process of the control method proposed by the present invention is Figure 2 .

[0038] Legend:

[0039] 1. Loading table; 2. Support member; 201. Slide; 3. Adjustment assembly; 301. Connector; 302. Rotating shaft; 4. Transfer mechanism; 5. Sampling needle; 6. Needle removal block; 7. Needle holder; 8. First sample plate holder; 9. Second sample plate holder; 10. Cover plate; 11. Holder pressure ring; 12. Recycling box. DETAILED DESCRIPTION

[0040] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0041] Reference Figure 1-Figure 5 An embodiment of the present invention provides: a mass spectrometer sampling device, comprising: a loading table 1; a support 2 and an adjustment component 3 are arranged on the loading table 1; the adjustment component 3 includes a plurality of connecting members 301, any connecting member 301 is slidably connected to the support 2, and moves along the setting direction of the support 2, and the plurality of connecting members 301 are rotatably connected in sequence; a pipetting mechanism 4 is arranged below the connecting member 301 on the side away from the support 2, and the pipetting mechanism 4 cooperates with the sampling needle 5; a needle removal block 6 is also arranged on the loading table 1, and the pipetting mechanism 4 drives the sampling needle 5 to move to the needle removal block 6 to separate the sampling needle 5 from the pipetting mechanism 4.

[0042] In this embodiment, a vertically mounted support member 2 is provided on the loading table 1, an adjusting component 3 is installed on the support member 2, a pipetting mechanism 4 is provided below one end of the adjusting component 3, the lower end of the pipetting mechanism 4 is connected to the sampling needle 5, the pipetting mechanism 4 and the sampling needle 5 are transitionally matched, so that the lower end of the pipetting mechanism 4 is inserted into the inner side of one end of the sampling needle 5 for installation, when performing sampling pipetting operation, the adjusting component 3 moves along the vertical direction of the support member 2 to adjust the height, and several connecting members 301 of the adjusting component 3 rotate through the rotating shaft to extend the adjusting component 3 outward, driving the pipetting mechanism 4 to move to the first sample plate bracket 8, the second sample plate bracket 9 or the injection position to perform pipetting operation, and the sampling needle after pipetting is moved to the needle retrieval block 6 by the adjusting component 3, the pipetting mechanism 4 cooperates with the notch on one side of the needle retrieval block 6, and the sampling needle 5 is located below the needle retrieval block 6, and the adjusting component 3 is moved upward to make the pipetting mechanism 4 detach from the inner side of the sampling needle 5 to complete the needle retrieval operation.

[0043] The injection coordinates are flexible, and the pipetting mechanism can be dragged to locate the injection position and set the current injection position. There is no need to repeatedly debug through coordinate input. The layout can be moved as needed, does not occupy a compact experimental space, and has better applicability.

[0044] Reference Figure 2 , where the blue area is the operating platform for placing the control computer and samples, and the green area is the effective activity area of ​​the adjustment component 3.

[0045] The sample plate can be set up flexibly and can hold a large number of samples. Samples stored in different containers can be tested by simply replacing the sample plate holder. Large batches of samples can also be processed at one time, with a maximum of 384 pieces * 2 groups.

[0046] A groove is provided on the loading table 1, and a needle holder 7, a first sample plate holder 8 and a second sample plate holder 9 are placed inside the groove. A cover plate 10 is provided on the first sample plate holder 8, and a holder pressing ring 11 is provided on one side of the groove. A plurality of sampling needles 5 are placed inside the needle holder 7, and the pipetting mechanism 4 moves to the sampling needle 5 through the adjusting component 3, and moves downward to cooperate with the sampling needle 5.

[0047] In this embodiment, the bracket pressure ring 11 includes a pressure plate and a rotating shaft, and the pressure plate rotating shaft is integrally connected so that the pressure plate can be rotated to the top of the groove on the loading table 1, and the lower ends of the needle holder 7, the first sample plate holder 8 and the second sample plate holder 9 are arranged on the inner side of the groove, and the pressure plate limits the lower ends of the needle holder 7, the first sample plate holder 8 and the second sample plate holder 9. There are multiple bracket pressure rings 11, so that the needle holder 7, the first sample plate holder 8 and the second sample plate holder 9 in the groove can be placed more stably. The first sample plate holder 8 and the second sample plate holder 9 can be selected in different sizes according to actual needs, and can be adapted to a variety of sample containers to meet sampling requirements.

[0048] There are two needle holders 7, which can hold needles of different types. Each needle holder 7 is provided with 96 working positions, and different sampling needles 5 can be installed on the pipetting mechanism 4 as needed. The first sample holder 8 is an EP tube (sample bottle) placement holder, and the second sample plate holder 9 is a well plate placement holder, both of which are provided with 96 sample positions. When sampling, the liquid in the sample position can be pipetted in sequence according to the set order and moved to the injection position of the mass spectrometer.

[0049] A slide groove 201 is provided on the support member 2, one end of the connecting member 301 is installed on the slide groove 201 and moves along the setting direction of the slide groove 201, and the other side of the connecting member 301 is connected to another connecting member 301 through a rotating shaft 302, and the rotating shaft 302 is driven to rotate by a motor.

[0050] In this embodiment, a worm gear structure driven by a motor is provided on the inner side of the support member 2, which is connected to one side of the adjustment component 3 through a slide groove 201 to control the height position of the adjustment component 3 in the vertical direction. The adjustment component 3 includes three connecting members 301 connected in sequence, and two adjacent connecting members 301 are connected by a rotating shaft 302. A motor is provided on the inner side of the connecting member 301, and the rotating shaft 302 is connected to the gear. A driving gear is provided at the output end of the motor to drive the rotating shaft 302 to rotate. The motor in this application is a stepping motor, which can accurately control the number of rotations and angles of the motor, and can adjust the height position of the component 3 and the moving position of the pipetting mechanism 4.

[0051] A recovery box 12 is also provided on the loading table 1 , and the recovery box 12 is arranged below the needle removal block 6 .

[0052] In this embodiment, the sampling needle 5 on the inner side of the needle holder 7 is a disposable sampling needle. After sampling and pipetting the liquid in the first sample plate holder 8 and the second sample plate holder 9, the sampling needle is removed and collected in the recovery box 12. The recovery box 12 is arranged below the needle retrieval block 6. The sampling needle 5 that falls through the needle retrieval block 6 falls into the inner side of the recovery box 12.

[0053] Reference Figure 6 , also includes an embodiment of a control method, the control method is applicable to the sample injection device of any one of the above technical solutions, including:

[0054] S1: Obtain the position information of the origin, the pipetting mechanism, the needle holder, the first sample plate holder, the second sample plate holder and the injection, and perform collision detection.

[0055] S2: Determine whether there is a sampling needle at the pipetting mechanism. If yes, return to the origin to remove the sampling needle. If no, control the pipetting mechanism to move to the needle holder.

[0056] S3: Control the support and the adjustment component to move, drive the pipetting mechanism to press down and install the sampling needle, move to the first sample holder or the second sample holder to take samples, and after completion, move up and out of the sampling needle to hover;

[0057] S4: Control the pipetting mechanism to move to the injection position, discharge the liquid, and move out of the injection position after standing still, and return to step S2.

[0058] In this embodiment, the loading table 1 is placed on a movable lifting table, and the physical three-point positioning marked on the lifting table matches the physical three-point positioning of the mass spectrometer table to prevent displacement deviation during each movement. The machine is powered on and initialized for self-test. After the self-test is completed, the software interface is entered, including:

[0059] Main interface: The main interface for users to operate injection. Users can import the method to be injected and start the injection operation in this interface.

[0060] Method interface: Users can create the required injection method in this interface, and name and save the method to provide method import and use for injection operations. It is divided into three parts: method editing area, method import and save area, and injection position setting area.

[0061] Method editing area: You can edit each important parameter of a single or multiple injection processes in the method, and you can copy, delete, add, move up, and move down a single injection process.

[0062] Method import and save area: import existing methods, modify and save methods, and save as new methods.

[0063] Injection position setting area: Set the injection position; the injection positions corresponding to all methods (generally the ion source position) are the same in principle. In the injection position setting area, the injection position can be adjusted, set, calibrated and reset.

[0064] When a single injection is used to import sequence injection content, only the first data of the sequence injection method will be read, and the default number of repetitions is 1.

[0065] When there is only one record, the system exports it as a single injection method by default. If there are multiple records, the system exports them as a sequential injection method.

[0066] Record interface: Save a series of records after the user's injection operation. The user can quickly find the completed historical injection records in this interface, and can export them as Excel files, export data in multiple dimensions, and sort from the most recent data to the furthest.

[0067] Coordinate interface: mainly used to calibrate and reset the origin coordinates of the device when the device is moved or at the user's subjective demand. It is used to calibrate the origin coordinates of the entire device of the support 2. It provides calibration to take into account the possible origin offset of the device after the device is moved. There is no need to install the sampling needle 5 to calibrate the origin coordinates.

[0068] The position information of the origin, the pipetting mechanism, the needle support, the first sample plate support, the second sample plate support and the injection is obtained through the software interface.

[0069] Before installing the sampling needle 5, first identify whether the last action is to remove the sampling needle, and determine whether there is a sampling needle at the pipetting mechanism. If yes, drive the pipetting mechanism 4 and the sampling needle 5 to move to the needle removal block 6. If not, enter the operation of installing the sampling needle 5. Move to the position of the sampling needle 5, pick up the sampling needle 5 from the position after the last installation of the sampling needle 5, or pick up the sampling needle 5 from the specified position. The sampling needle 5 has 96 positions, 8*12 (vertical row*horizontal row). The picking order is to pick up the second vertical row after the first vertical row is taken. Only one sampling needle is picked up at a time. Starting from the first picking position, the subsequent order defaults to full sampling needles on this plate position, and there is no vacancy (no skip).

[0070] The pipetting mechanism 4 and the sampling needle 5 move to the set sample position, descend to the suction height, suck a fixed volume of liquid, stand for t1 seconds, and rise to the set height h (when the height is h, there will be no interference when carrying the gun head to do xy movement). After the sample is sucked, move to the set injection position. Drain the liquid in the sampling needle 5, stand for t2 seconds, and move out of the injection position.

[0071] Reference Figure 7 , collision detection includes:

[0072] S11: setting the origin position, dragging the pipetting mechanism to the needle support, the first sample plate support, the second sample plate support and the injection position, and saving the position information;

[0073] S12: Control the sample injection process to test run and detect whether a collision occurs. If yes, control the pipetting mechanism to save at the current position point, add position compensation information, and perform position calibration. If no, control the pipetting mechanism to return to the origin position.

[0074] In this embodiment, in the method interface, the injection position area performs an ion source injection position adjustment. It is recommended to use a combination of dragging and mouse clicking when adjusting. When dragging the pipetting mechanism 4, leave a margin and do not reach the limit point of the moving distance of the adjustment component 3. Adjust to a suitable position and save the current position information.

[0075] Returning to the origin to remove the sampling needle includes: controlling the pipetting mechanism to move to the origin, the origin is below the needle removal block, and after reaching the origin, controlling the pipetting mechanism to move upward to remove the sampling needle.

[0076] In another embodiment, a computer-readable storage medium is further included, which stores a computer program for running the control method, wherein the computer program causes a computer to execute the following steps:

[0077] S1: Obtain the position information of the origin, the pipetting mechanism, the needle holder, the first sample plate holder, the second sample plate holder and the injection, and perform collision detection.

[0078] S2: Determine whether there is a sampling needle at the pipetting mechanism. If yes, return to the origin to remove the sampling needle. If no, control the pipetting mechanism to move to the needle holder.

[0079] S3: Control the support and the adjustment component to move, drive the pipetting mechanism to press down and install the sampling needle, move to the first sample holder or the second sample holder to take samples, and after completion, move up and out of the sampling needle to hover;

[0080] S4: Control the pipetting mechanism to move to the injection position, discharge the liquid, and move out of the injection position after standing still, and return to step S2.

[0081] Among them, the computer-readable storage medium can be a computer storage medium or a communication medium. The communication medium includes any medium that facilitates the transmission of a computer program from one place to another. The computer storage medium can be any available medium that can be accessed by a general-purpose or special-purpose computer. For example, a computer-readable storage medium is coupled to a processor so that the processor can read information from the computer-readable storage medium and write information to the computer-readable storage medium. Of course, the computer-readable storage medium can also be a component of the processor. The processor and the computer-readable storage medium can be located in an application-specific integrated circuit (ASIC). In addition, the ASIC can be located in a user device. Of course, the processor and the computer-readable storage medium can also exist in a communication device as discrete components.

[0082] Specifically, the computer-readable storage medium can be implemented by any type of volatile or non-volatile storage device or a combination thereof, such as static random access memory (SRAM), electrically erasable programmable read-only memory (EEPROM), erasable programmable read-only memory (EPROM), programmable read-only memory (PROM), read-only memory (ROM), magnetic memory, flash memory, magnetic disk or optical disk. The storage medium can be any available medium that can be accessed by a general or special-purpose computer.

[0083] In another embodiment, an electronic device is also included, including:

[0084] one or more processors; memory; and

[0085] One or more programs, wherein the one or more programs are stored in the memory and configured to be executed by one or more processors, the programs comprising steps for performing the following steps:

[0086] S1: Obtain the position information of the origin, the pipetting mechanism, the needle holder, the first sample plate holder, the second sample plate holder and the injection, and perform collision detection.

[0087] S2: Determine whether there is a sampling needle at the pipetting mechanism. If yes, return to the origin to remove the sampling needle. If no, control the pipetting mechanism to move to the needle holder.

[0088] S3: Control the support and the adjustment component to move, drive the pipetting mechanism to press down and install the sampling needle, move to the first sample holder or the second sample holder to take samples, and after completion, move up and out of the sampling needle to hover;

[0089] S4: Control the pipetting mechanism to move to the injection position, discharge the liquid, and move out of the injection position after standing still, and return to step S2.

[0090] Memory is used to store computer programs. The memory may include high-speed random access memory (RAM) and may also include non-volatile memory (NVM), such as at least one disk memory, and may also be a USB flash drive, a mobile hard disk, a read-only memory, a disk or an optical disk.

[0091] The processor is used to execute the computer program stored in the memory to implement the control method in the above embodiment. The processor can be a central processing unit (CPU), or other general-purpose processors, digital signal processors (DSP), application-specific integrated circuits (ASIC), etc. The general-purpose processor can be a microprocessor or the processor can also be any conventional processor, etc. The steps of the method disclosed in the invention can be directly embodied as being executed by a hardware processor, or can be executed by a combination of hardware and software modules in the processor.

[0092] Optionally, the memory can be independent or integrated with the processor.

[0093] When the memory is a device independent of the processor, the electronic device may further include a bus. The bus is used to connect the memory and the processor. The bus may be an Industry Standard Architecture (ISA) bus, a Peripheral Component Interconnect (PCI) bus, or an Extended Industry Standard Architecture (EISA) bus. The bus may be divided into an address bus, a data bus, a control bus, and the like.

[0094] It should be noted that, through the description of the above embodiments, those skilled in the art can clearly understand that each embodiment can be implemented by means of software plus a necessary general hardware platform. Based on such an understanding, the above technical solution is essentially or the part that contributes to the prior art can be embodied in the form of a software product, which can be stored in a computer-readable storage medium, such as ROM / RAM, a disk, an optical disk, etc., including several instructions to enable a computer device (which can be a personal computer, a server, or a network device, etc.) to execute the methods described in each embodiment or some parts of the embodiment. In this article, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply that there is any such actual relationship or order between these entities or operations. Moreover, the term "include", "comprise" or any other variant thereof is intended to cover non-exclusive inclusion, so that the process, method, article or device including a series of elements includes not only those elements, but also includes other elements that are not explicitly listed, or also includes elements inherent to such process, method, article or device. Without more constraints, an element defined by the phrase "comprising a..." does not exclude the existence of other identical elements in the process, method, article or apparatus comprising the element.

[0095] Finally, it should be noted that the above is only a preferred embodiment of the present invention and is not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, it is still possible for those skilled in the art to modify the technical solutions described in the aforementioned embodiments or to make equivalent substitutions for some of the technical features therein. Any modifications, equivalent substitutions, improvements, etc. made within the spirit and principles of the present invention should be included in the protection scope of the present invention.

Claims

1. A mass spectrometer sample injection device, characterized in that: include: Loading table (1); The loading table (1) is provided with a support member (2) and an adjustment component (3); The adjustment assembly (3) comprises a plurality of connecting members (301), any one of the connecting members (301) is slidably connected to the support member (2), moves along the setting direction of the support member (2), and a plurality of the connecting members (301) are rotatably connected in sequence; A liquid transfer mechanism (4) is provided below the connecting member (301) on a side away from the supporting member (2), and the liquid transfer mechanism (4) cooperates with the sampling needle (5); The loading table (1) is also provided with a needle retrieval block (6), and the liquid transfer mechanism (4) drives the sampling needle (5) to move to the needle retrieval block (6) to separate the sampling needle (5) from the liquid transfer mechanism (4).

2. The sample injection device according to claim 1, characterized in that: The loading table (1) is provided with a groove, a needle holder (7), a first sample plate holder (8) and a second sample plate holder (9) are placed inside the groove, a cover plate (10) is provided on the first sample plate holder (8), and a holder pressure ring (11) is provided on one side of the groove.

3. The sample injection device according to claim 2, characterized in that: A plurality of sampling needles (5) are placed inside the needle holder (7), and the liquid transfer mechanism (4) moves to the sampling needles (5) through the adjustment component (3) and moves downward to cooperate with the sampling needles (5).

4. The sample injection device according to claim 1, characterized in that: The support member (2) is provided with a slide groove (201), one end of the connecting member (301) is installed on the slide groove (201) and moves along the setting direction of the slide groove (201), and the other side of the connecting member (301) is connected to another connecting member (301) through a rotating shaft (302), and the rotating shaft (302) is driven to rotate by a motor.

5. The sample injection device according to claim 1, characterized in that: The loading table (1) is also provided with a recovery box (12), and the recovery box (12) is arranged below the needle removal block (6).

6. A control method, characterized in that: The control method is applicable to the sample injection device according to any one of claims 1 to 5, comprising: S1: Obtain the position information of the origin, the pipetting mechanism, the needle holder, the first sample plate holder, the second sample plate holder and the injection, and perform collision detection. S2: Determine whether there is a sampling needle at the pipetting mechanism. If yes, return to the origin to remove the sampling needle. If no, control the pipetting mechanism to move to the needle holder. S3: Control the support and the adjustment component to move, drive the pipetting mechanism to press down and install the sampling needle, move to the first sample holder or the second sample holder to take samples, and after completion, move up and out of the sampling needle to hover; S4: Control the pipetting mechanism to move to the injection position, discharge the liquid, and move out of the injection position after standing still, and return to step S2.

7. The control method according to claim 6, characterized in that: The collision detection includes: S11: setting the origin position, dragging the pipetting mechanism to the needle support, the first sample plate support, the second sample plate support and the injection position, and saving the position information; S12: Control the sample injection process to test run and detect whether a collision occurs. If yes, control the pipetting mechanism to save at the current position point, add position compensation information, and perform position calibration. If no, control the pipetting mechanism to return to the origin position.

8. The control method according to claim 6, characterized in that: The returning to the origin to remove the sampling needle comprises: controlling the liquid transfer mechanism to move to the origin, the origin being below the needle removal block, and after reaching the origin, controlling the liquid transfer mechanism to move upward to remove the sampling needle.

9. A computer-readable storage medium, characterized in that: It stores a computer program for running the control method, wherein the computer program enables a computer to execute the control method according to any one of claims 6 to 8.

10. An electronic device, characterized in that: include: one or more processors; Memory; as well as One or more programs, wherein the one or more programs are stored in the memory and are configured to be executed by the one or more processors, the programs including instructions for executing the control method according to any one of claims 6 to 8.

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