Ginsenoside-containing extract protein line composition, application and shampoo

By using ginseng extract protein line composition in shampoo, the problem of easy degradation and uneven dispersion of ginseng saponins is solved, and the stability and texture of shampoo are improved, and the smoothness, shine and oil-control effects of hair are enhanced.

CN119837778APending Publication Date: 2025-04-18FLEXIBLE BIOTECHNOLOGY (GUANGZHOU) CO LTD
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Patent Information

Application Number
CN202510021096.8
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-07
Publication Date
2025-04-18

AI Technical Summary

Technical Problem

Ginseng saponin is easy to degrade in shampoo, affecting stability and uniform dispersion, resulting in poor product texture and effect, and at the same time, it affects protein components, reducing activity or changing texture.

Method used

The ginseng extract protein line composition is used, including agar, pearl powder, synthetic fluorogen mica, sodium alginate, jojoba seed extract, hydroxypropyl cellulose, sodium hyaluronate, sodium benzoate, phenoxyethanol, keratin, hydrolyzed keratin, and oxidized keratin. By adjusting the particle size of the pearl powder, the molecular weight of hydroxypropyl cellulose and the preparation method of hydrolyzed keratin, the stability and sense of use of the composition are improved.

Benefits of technology

It improves the stability and texture of the shampoo, makes the product not easy to layer and feel smooth, enhances the smooth and shiny effect of the hair, and provides the effects of oil control, anti-hair loss and promoting hair roots.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to the technical field of daily chemicals, in particular to a panaxoside-containing extract protein thread composition, application and shampoo. The composition comprises agar, pearl powder, synthetic fluorophlogopite, sodium alginate, a simmondsia chinensis seed extract, hydroxy propyl cellulose, sodium hyaluronate, sodium benzoate, phenoxyethanol, keratin, hydrolyzed keratin, oxidized keratin and ginsenoside. Keratin, hydrolyzed keratin and oxidized keratin provide protein supplement, repair damaged hair cuticles and enhance the toughness of hair. Ginsenoside improves scalp microcirculation and promotes hair root nutrition supply. The sodium hyaluronate, the simmondsia chinensis seed extract and the sodium alginate are used for increasing the moisture content of hair and scalp and relieving dryness.
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Description

Technical Field

[0001] The invention relates to the technical field of daily chemicals, in particular to an extract protein thread composition containing ginsenoside, application and shampoo. Background Art

[0002] Ginsenosides are active ingredients extracted from ginseng (Panax ginseng). They belong to a class of steroid saponins and are one of the main pharmacological components of ginseng. Ginsenosides have multiple biological activities and are often used as active ingredients in traditional medicines, health foods and cosmetics.

[0003] Ginsenosides are mainly divided into two categories based on their chemical structure: Protopanaxadiol: usually including Rg1, Re, R1, Rb1, etc. Protopanaxatriol: mainly including Rg3, Rh2, Rb2, etc. The difference between these two types of ginsenosides lies in their glycosylation method and the type of saponin sugar.

[0004] Ginsenosides are used in shampoos, mainly to promote hair growth, resist hair loss, and nourish the scalp. They help maintain healthy hair by enhancing blood circulation and antioxidant capacity of the scalp. Ginsenosides are easily degraded under light, high temperature or oxidative conditions, affecting the stability of their active ingredients. Long-term storage may lead to the loss of active ingredients. At the same time, ginsenosides are water-soluble substances, but their solubility in water is low, especially high molecular weight saponins. Due to its complex molecular structure, it may be difficult to evenly disperse in shampoo, affecting the texture and effect of the product. At the same time, ginsenosides and protein ingredients may affect each other, reducing activity or changing the texture of shampoo.

[0005] To this end, the present invention provides a hair composition, application, and shampoo. Summary of the invention

[0006] In order to solve the above technical problems, the present invention provides a ginseng extract protein thread composition, which comprises:

[0007] Agar, pearl powder, synthetic fluorphlogopite, sodium alginate, jojoba (SIMMON DSIA CHINENSIS) seed extract, hydroxypropyl cellulose, sodium hyaluronate, sodium benzoate, phenoxyethanol, keratin, hydrolyzed keratin, oxidized keratin, ginsenosides.

[0008] As an embodiment of the present invention, the pearl powder has a particle size of <5 μm and a mixture of pearl powder of 5 to 15 μm, and the mixing ratio is 4:1.

[0009] As an embodiment of the present invention, the molecular weight of the hydroxypropyl cellulose is 10,000 to 50,000 Da and / or 50,000 to 150,000 Da.

[0010] As an embodiment of the present invention, the hydrolyzed keratin is obtained by fermentation and hydrolysis of bacterial species.

[0011] As an embodiment of the present invention, the bacterial species are Bacillus and lactic acid bacteria.

[0012] As an embodiment of the present invention, the composition comprises, by mass ratio:

[0013] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0014] The invention provides the hair composition, which is applied in the field of hair daily chemicals.

[0015] The invention provides a shampoo comprising the hair composition.

[0016] As an embodiment of the present invention, the preparation raw materials include: 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and up to 100 parts of water.

[0017] By adopting the above technical solution, the present invention has the following beneficial effects:

[0018] Keratin, hydrolyzed keratin, oxidized keratin: provide protein supplement, repair damaged hair scales, and enhance hair strength.

[0019] Ginsenoside improves scalp microcirculation and promotes nutrient supply to hair roots.

[0020] Sodium Hyaluronate, Jojoba Seed Extract, Sodium Alginate: Increase moisture content in hair and scalp, relieve dryness.

[0021] Pearl powder, synthetic fluorphlogopite: provide visual brightening effect, making hair smoother and shinier.

[0022] Jojoba seed extract has an oil-control effect and balances the oil secretion of the scalp.

[0023] Agar, sodium alginate and hydroxypropyl cellulose work together to improve the texture of the shampoo, making the product less likely to separate and smoother to the touch.

[0024] Synthetic fluorphlogopite and pearl powder bring pearly luster and smooth texture, enhancing the visual and tactile experience of the shampoo.

[0025] The main ingredients are natural extracts (such as jojoba seeds and ginsenosides), combined with safe preservatives (sodium benzoate and phenoxyethanol), making it suitable for sensitive scalps. DETAILED DESCRIPTION

[0026] The technical solution of the present invention will be described clearly and completely below. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of them. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0027] The present invention provides a hair composition, which comprises, by weight ratio:

[0028] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0029] The pearl powder is a mixture of pearl powder with a particle size less than 5 μm and pearl powder with a particle size of 5 to 15 μm, and the mixing mass ratio is 4:1.

[0030] The hydroxypropyl cellulose is a mixture of cellulose with a molecular weight of 10,000 to 50,000 Da and cellulose with a molecular weight of 50,000 to 150,000 Da, and the mixing mass ratio is 2:3.

[0031] The preparation method of the hydrolyzed protein is as follows: commercially available keratin and culture medium are mixed at a mass ratio of 1:10, 8% of the bacteria are inoculated after the mixture is evenly mixed, and then aeration fermentation is carried out at 37° C. for 36 hours. After the fermentation is completed, solid impurities in the fermentation liquid are filtered to obtain a filtrate; the hydrolyzed keratin can be obtained.

[0032] Among them, the bacterial strains include Bacillus and lactic acid bacteria, and the inoculation ratio is 3:1; the components of the culture medium include: glucose: 20g / L, yeast extract: 5g / L, ammonium sulfate: 2g / L, sodium dihydrogen phosphate: 2g / L, magnesium sulfate: 0.5g / L, calcium sulfate: 0.5g / L, cystine: 0.05g / L, water: to 1L.

[0033] The present invention also provides a shampoo comprising the hair composition.

[0034] As an embodiment of the present invention, the raw materials for preparation thereof include:

[0035] 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and water to 100 parts.

[0036] Granular ingredients such as pearl powder may cause suspension stability problems, leading to precipitation or stratification. The present invention effectively solves related stability problems by adjusting the particle size relationship ratio of pearl powder; the flaky structure of synthetic fluorphlogopite can adhere to the hair, fill the unevenness between the hair scales, and make the hair feel smoother. At the same time, the flaky structure of synthetic fluorphlogopite can also solve the suspension problem; matching the agar in the formula, the gel network helps to encapsulate the active ingredients (such as ginsenosides) in the product to prevent its degradation. The presence of hydroxypropyl cellulose will also make consumers feel that the product is sticky and the shampoo cannot be washed cleanly. The present invention adjusts the molecular weight relationship of hydroxypropyl cellulose and matches the mass ratio of synthetic fluorphlogopite to improve the feel of use.

[0037] At the same time, natural keratin has a highly cross-linked disulfide bond network structure, and its chemical properties are very stable. It is insoluble in water and most solvents. The hydrolysis treatment decomposes keratin into small molecular polypeptides or amino acids, which solves the problem of its large molecular weight and difficulty in solubility. However, the acid-base hydrolysis method may cause some amino acids to degrade and their functionality to be impaired, such as cysteine ​​and lysine are easily destroyed. The hydrolysis process is difficult to fully control, resulting in a wide molecular weight distribution, which may affect the consistency and functional effects of the product. For this reason, the present invention uses a bacterial fermentation method to controllably decompose keratin. Through the mutual containment of the bacterial strains and the low amount of components in the culture medium, a metabolic inhibition environment is provided, which can temporarily inhibit the excessive damage of the enzyme to the disulfide bonds.

[0038] In addition, considering the stability of the overall formula, adding surfactants and stabilizers of specific components into the formula makes the formula more stable without affecting the efficacy of the product.

[0039] The present invention is further explained below in conjunction with specific implementation modes.

[0040] Example 1

[0041] This embodiment provides a ginseng extract protein thread composition, which comprises, by mass ratio:

[0042] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0043] The pearl powder is a mixture of pearl powder with a particle size less than 5 μm and pearl powder with a particle size of 5 to 15 μm, and the mixing mass ratio is 4:1.

[0044] The hydroxypropyl cellulose is a mixture of cellulose with a molecular weight of 10,000 to 50,000 Da and cellulose with a molecular weight of 50,000 to 150,000 Da, and the mixing mass ratio is 2:3.

[0045] The preparation method of the hydrolyzed protein is as follows: commercially available keratin and culture medium are mixed at a mass ratio of 1:10, 8% of the bacteria are inoculated after the mixture is evenly mixed, and then aeration fermentation is carried out at 37° C. for 36 hours. After the fermentation is completed, solid impurities in the fermentation liquid are filtered to obtain a filtrate; the hydrolyzed keratin can be obtained.

[0046] Among them, the bacterial strains include Bacillus and lactic acid bacteria, and the inoculation ratio is 3:1; the components of the culture medium include: glucose: 20g / L, yeast extract: 5g / L, ammonium sulfate: 2g / L, sodium dihydrogen phosphate: 2g / L, magnesium sulfate: 0.5g / L, calcium sulfate: 0.5g / L, cystine: 0.05g / L, water: to 1L.

[0047] This embodiment also provides a shampoo, the raw materials for its preparation include:

[0048] 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and water to 100 parts.

[0049] Example 2

[0050] This embodiment provides a ginseng extract protein thread composition, which comprises, by mass ratio:

[0051] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0052] The pearl powder has a particle size of less than 5 μm.

[0053] The molecular weight of the hydroxypropyl cellulose is 10000-50000Da.

[0054] The preparation method of the hydrolyzed protein is as follows: commercially available keratin and culture medium are mixed at a mass ratio of 1:10, 8% of the bacteria are inoculated after the mixture is evenly mixed, and then aeration fermentation is carried out at 37° C. for 36 hours. After the fermentation is completed, solid impurities in the fermentation liquid are filtered to obtain a filtrate; the hydrolyzed keratin can be obtained.

[0055] Among them, the bacterial strains include Bacillus and lactic acid bacteria, and the inoculation ratio is 3:1; the components of the culture medium include: glucose: 20g / L, yeast extract: 5g / L, ammonium sulfate: 2g / L, sodium dihydrogen phosphate: 2g / L, magnesium sulfate: 0.5g / L, calcium sulfate: 0.5g / L, cystine: 0.05g / L, water: to 1L.

[0056] This embodiment also provides a shampoo, the raw materials for its preparation include:

[0057] 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and water to 100 parts.

[0058] Example 3

[0059] This embodiment provides a ginseng extract protein thread composition, which comprises, by mass ratio:

[0060] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0061] The pearl powder is a mixture of pearl powder with a particle size less than 5 μm and pearl powder with a particle size of 5 to 15 μm, and the mixing mass ratio is 4:1.

[0062] The hydroxypropyl cellulose is a mixture of cellulose with a molecular weight of 10,000 to 50,000 Da and cellulose with a molecular weight of 50,000 to 150,000 Da, and the mixing mass ratio is 2:3.

[0063] The hydrolyzed protein is commercially available.

[0064] This embodiment also provides a shampoo, the raw materials for its preparation include:

[0065] 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and water to 100 parts.

[0066] Example 4

[0067] This embodiment provides a ginseng extract protein thread composition, which comprises, by mass ratio:

[0068] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0069] The pearl powder is a mixture of pearl powder with a particle size less than 5 μm and pearl powder with a particle size of 5 to 15 μm, and the mixing mass ratio is 4:1.

[0070] The hydroxypropyl cellulose is a mixture of cellulose with a molecular weight of 10,000 to 50,000 Da and cellulose with a molecular weight of 50,000 to 150,000 Da, and the mixing mass ratio is 2:3.

[0071] The preparation method of the hydrolyzed protein is as follows: commercially available keratin and culture medium are mixed at a mass ratio of 1:10, 8% of the bacteria are inoculated after the mixture is evenly mixed, and then aeration fermentation is carried out at 37° C. for 36 hours. After the fermentation is completed, solid impurities in the fermentation liquid are filtered to obtain a filtrate; the hydrolyzed keratin can be obtained.

[0072] Among them, the bacterial species is Bacillus; the components of the culture medium include: glucose: 20g / L, yeast extract: 5g / L, ammonium sulfate: 2g / L, sodium dihydrogen phosphate: 2g / L, magnesium sulfate: 0.5g / L, calcium sulfate: 0.5g / L, water: to 1L.

[0073] This embodiment also provides a shampoo, the raw materials for its preparation include:

[0074] 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thuja Orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and up to 100 parts of water.

[0075] Example 5

[0076] This embodiment provides a ginseng extract protein thread composition, which comprises, by mass ratio:

[0077] Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:3.

[0078] The pearl powder is a mixture of pearl powder with a particle size less than 5 μm and pearl powder with a particle size of 5 to 15 μm, and the mixing mass ratio is 4:1.

[0079] The hydroxypropyl cellulose is a mixture of cellulose with a molecular weight of 10,000 to 50,000 Da and cellulose with a molecular weight of 50,000 to 150,000 Da, and the mixing mass ratio is 2:3.

[0080] The preparation method of the hydrolyzed protein is as follows: commercially available keratin and culture medium are mixed at a mass ratio of 1:10, 8% of the bacteria are inoculated after the mixture is evenly mixed, and then aeration fermentation is carried out at 37° C. for 36 hours. After the fermentation is completed, solid impurities in the fermentation liquid are filtered to obtain a filtrate; the hydrolyzed keratin can be obtained.

[0081] Among them, the bacterial strains include Bacillus and lactic acid bacteria, and the inoculation ratio is 3:1; the components of the culture medium include: glucose: 20g / L, yeast extract: 5g / L, ammonium sulfate: 2g / L, sodium dihydrogen phosphate: 2g / L, magnesium sulfate: 0.5g / L, calcium sulfate: 0.5g / L, cystine: 0.05g / L, water: to 1L.

[0082] This embodiment also provides a shampoo, the raw materials for its preparation include:

[0083] 6 parts of hair composition, 8 parts of sodium lauryl ether sulfate, 9 parts of sodium lauroyl glutamate, 0.3 parts of Thuja orientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of Polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and up to 100 parts of water.

[0084] Performance Testing

[0085] Test 1: The shampoos prepared in Examples 1 to 5 were placed in thermostats at 48°C, 5°C, and 25°C, respectively. After the samples were restored to room temperature on the 30th day, the color appearance of the samples and whether the solutions had faded, stratified, or precipitated were observed.

[0086] The stability of hot and cold cycles was tested by a 2-day hot and cold cycle. The solution was placed in a -18°C constant temperature box for the first day and in a 48°C constant temperature box for the second day. The appearance of the solution was observed after returning to room temperature. A total of five cycles were monitored.

[0087] Table 1 Test results of test 1

[0088] Example 0℃ 25℃ 40℃ Hot and cold cycle experiment Example 1 No change No change No change No change Example 2 No change No change Slightly delaminated Slightly delaminated Example 3 Slight flocculation No change Slight flocculation Flocculation Example 4 Slight flocculation No change Slight flocculation Flocculation Example 5 Slightly delaminated No change Slightly delaminated Layering

[0089] Test 2: Human trial of anti-hair loss cosmetics

[0090] 1. Materials and Methods

[0091] 1. Trial material: Examples 1 to 5

[0092] 2. Subjects: A total of 35 subjects, including 12 males and 23 females, aged 25 to 60 years old, with an average age of 41.31±10.34 years old, met the voluntary inclusion criteria.

[0093] 3. Trial method: Have the subjects use the test product directly according to the usage characteristics and methods indicated on the cosmetic product label, observe or follow up by phone once a week for the skin reactions of the subjects, and record the results according to the grading standards for adverse skin reactions in human trial tests in the "Technical Specifications for Safety of Cosmetics" (2015 edition). The trial period shall be no less than 4 weeks.

[0094] Table 2 Test results of test 2

[0095]

[0096] Test 3: Cosmetic anti-hair loss efficacy test

[0097] Materials and methods

[0098] 1. Test product: Example 1

[0099] 2. Comparative product: Example 2 to Example 5

[0100] 3. Wash-out products: Same as the control products. Both the test group and the control group use the control products during the wash-out period.

[0101] 4. Instruments and Equipment

[0102] 4.1 Professional digital camera: The pixel is not less than 15 million. The parameters including aperture size, sensitivity (ISO) and focal length should remain consistent throughout the test.

[0103] 4.2 Image shooting bracket: It can fix the position of the subject's head so that the top of the head is perpendicular to the camera lens, and use a professional digital camera to take photos of all the hair with the top of the head as the center.

[0104] 4.3 Dermatoscope: LED light source, wavelength 450-750nm, color temperature 6500-8000K, illumination not less than 540lx, magnification ≥20 times, detection diameter not less than 1.0cm or area not less than 0.8cm 2 .

[0105] 4.4 Comb: The tooth density is moderate (tooth spacing 0.9-1.1mm), the tooth length is 2.0-3.0cm, and the comb length is not less than 10cm (excluding the comb handle). The comb of the same specification and material must be used throughout the test. After each use, it must be disinfected in accordance with the relevant requirements of the "Technical Specifications for Disinfection of Medical Institutions" (WS-T 367-2012).

[0106] 5. Subjects: A total of 45 subjects completed the test, aged 25 to 60 years old, including 12 males and 33 females, with an average age of 40.31±7.65 years old. They met the voluntary inclusion and exclusion criteria.

[0107] 6. Test method: The test shall be carried out in accordance with the specific requirements of the currently valid technical specifications and methods. Subjects who pass the initial screening are required to undergo a 2-week wash-out period, and will be screened again after the wash-out period. Qualified subjects selected for the formal trial are divided into the test group and the control group according to the stratified random method, and the test product and the control product are distributed respectively. Use the product correctly according to the product instructions. During the 12-week trial, subjects are required to keep a usage diary and strictly abide by the restrictions. Visits are conducted before product use (baseline value) and 12 weeks after use. The visits are for hair loss counts, assessment of local hair density, visual assessment of hair density, image capture, and records.

[0108] Table 3 Test results of test 3

[0109]

[0110] Test 4: Comprehensive evaluation experiment on human trials: The candidates for this test are the same as those for test 3, and the evaluation is conducted 30 days after the samples are used.

[0111] Table 4 User experience rating table

[0112]

[0113]

[0114] 5 points means completely agree, 4 points means relatively agree, 3 points means neither agree nor disagree, 2 points means relatively disagree, and 1 point means completely disagree. There are 45 people in total, and the total number of records is in Table 5.

[0115] Table 5 Test results of test 4

[0116] Example Example 1 Example 2 Example 3 Example 4 Example 5 Question 1 223 187 193 200 192 Question 2 220 213 169 202 201 Question 3 218 207 192 210 209 Question 4 220 179 186 199 180 Question 5 219 190 186 203 183

[0117] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit it. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that they can still modify the technical solutions described in the aforementioned embodiments, or replace some or all of the technical features therein with equivalents. However, these modifications or replacements do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention.

Claims

1. A ginsenoside-containing extract protein thread composition, characterized in that: The composition comprises: Agar, pearl powder, synthetic fluorphlogopite, sodium alginate, jojoba seed extract, hydroxypropyl cellulose, sodium hyaluronate, sodium benzoate, phenoxyethanol, keratin, hydrolyzed keratin, oxidized keratin, ginsenosides.

2. The composition according to claim 1, characterized in that The pearl powder has a particle size of <5 μm and a mixture of pearl powder of 5 to 15 μm, and the mixing ratio is 4:

1.

3. The hair composition according to claim 1, characterized in that The molecular weight of the hydroxypropyl cellulose is 10,000 to 50,000 Da and / or 50,000 to 150,000 Da.

4. The composition according to claim 1, characterized in that The hydrolyzed keratin is obtained by fermentation and hydrolysis of bacterial species.

5. The composition according to claim 4, characterized in that The bacterial species are bacillus and lactic acid bacteria.

6. The composition according to claim 1, characterized in that According to the mass ratio, the composition comprises: Agar: pearl powder: synthetic fluorphlogopite: sodium alginate: jojoba (SIMMON DSIA CHINENSIS) seed extract: hydroxypropyl cellulose: sodium hyaluronate: sodium benzoate: phenoxyethanol: keratin: hydrolyzed keratin: oxidized keratin: ginsenoside is 10:5:0.68:1.5:0.8:1:0.5:0.4:0.0132:0.80678:0.0138:0.006:

3.

7. The composition according to any one of claims 1 to 6, used in the field of hair care products.

8. A shampoo, characterized in that: A composition comprising any one of claims 1 to 6.

9. The shampoo according to claim 8, characterized in that The preparation raw materials include: 6 parts of hair composition, 8 parts of cocamidopropyl betaine, 6 parts of potassium cocoyl glycinate, 3 parts of sodium myristoyl glutamate, 0.3 parts of Thujaorientalis leaf extract, 0.08 parts of polyquaternium-22, 0.5 parts of ginseng root extract, 1.5 parts of cocamide MEA, 0.1 parts of soapberry extract, 0.2 parts of polygonum multiflorum extract, 0.2 parts of squalane, 0.1 parts of adenosine, and up to 100 parts of water.

Citation Information

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