Positioning mechanism and cyber knife animal treatment fixing device

By designing a positioning mechanism including atomized anesthesia and multi-point fixing devices, the problem of the inability of the radio wave knife to effectively restrain the head movement of animals and the serious harm caused by traditional anesthesia methods is solved, and stable fixation and precise treatment of animals are achieved.

CN119867989APending Publication Date: 2025-04-25AFFILIATED HUSN HOSPITAL OF FUDAN UNIV
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Patent Information

Application Number
CN202510111236.0
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-23
Publication Date
2025-04-25

AI Technical Summary

Technical Problem

The existing fixed devices for radio wave knife treatment of animals cannot effectively restrain the head movement of animals, resulting in irradiation deviation. In addition, traditional anesthesia methods have difficulty in controlling depth, slow awakening and great harm to animals.

Method used

A positioning mechanism is designed, including main components, anesthesia components and auxiliary components, and the stable fixation of the animal's head and body is achieved through atomizing anesthesia and multi-point fixation devices.

Benefits of technology

It achieves stable fixation of the animal's head and body, reduces damage to the animal, and improves the accuracy and stability of the wave knife treatment.

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Abstract

The invention relates to the technical field of radiotherapy, in particular to a positioning mechanism and a cyber knife animal treatment fixing device.The positioning mechanism and the cyber knife animal treatment fixing device.The positioning mechanism and the cyber knife animal treatment fixing device.The positioning mechanism comprises a main body component which comprises an end connecting block, an anesthesia assembly installed on the outer side of the end connecting block in a matched mode and an auxiliary assembly installed on the outer side of the end connecting block in a matched mode; the anesthesia assembly is used for anesthetizing an animal to be treated, and the two auxiliary assemblies are symmetrically arranged and used for fixing the head of the animal to be treated; through mutual cooperation of all the components, stable fixation of the head and the body of an animal can be achieved, injection anesthesia is replaced with atomization anesthesia, harm to the animal is reduced, after the body of the animal is fixed, through the design that a clamping block covers the top of a buckle, the situation that fixation is unstable due to buckle failure can be reduced, and the fixing effect is improved. And the fixing stability of the device is further enhanced.
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Description

Technical Field

[0001] The invention relates to the technical field of radiotherapy, in particular to a positioning mechanism and a CyberKnife animal treatment fixing device. Background Art

[0002] At present, in order to achieve the braking of experimental animals and ensure accurate radiation exposure during the CyberKnife treatment of animals, the animals are usually placed in a small square box after anesthesia to restrict their body movement and perform positioning and irradiation. This method usually fails to effectively restrict the movement of the animal's head, resulting in irradiation deviation. In addition, injection anesthesia is difficult to control the depth of anesthesia, slow awakening, heavy burden on the liver and kidneys, and traumatic operation in small animal experiments, which is not suitable for long-term experiments of CyberKnife positioning and treatment.

[0003] Existing fixation devices have limited adaptability under dynamic image guidance, especially in experiments that require high-precision target tracking. Traditional fixation solutions cannot meet the CyberKnife system's requirements for real-time position calibration. Summary of the invention

[0004] In view of the above problems in the prior art, the present invention is proposed.

[0005] Therefore, an object of the present invention is to provide a positioning mechanism.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions: a positioning mechanism, comprising:

[0007] A main body component, which includes an end connection block, an anesthesia component adapted to be installed outside the end connection block, and an auxiliary component adapted to be installed outside the end connection block;

[0008] The anesthesia component is used to anesthetize the animal receiving treatment, and the auxiliary components are symmetrically arranged in two groups, and the auxiliary components are used to fix the head of the animal receiving treatment.

[0009] As a preferred solution of the positioning mechanism of the present invention, the anesthesia component includes a catheter adapted to be installed inside the end connecting block, and an incisor fixture adapted to be installed at one end of the catheter.

[0010] As a preferred solution of the positioning mechanism of the present invention, the anesthesia component further comprises a liquid medicine pool adapted to be installed at the other end of the catheter, and a microporous piezoelectric atomizer adapted to be installed inside the liquid medicine pool;

[0011] Wherein, a top cover for sealing is arranged on the top of the medicine liquid pool.

[0012] As a preferred solution of the positioning mechanism of the present invention, the auxiliary component includes a support block fixedly connected to the outside of the end connection block, and a slider slidably connected to the inside of the support block.

[0013] As a preferred solution of the positioning mechanism of the present invention, the auxiliary component further comprises a lifting block slidably connected to the inside of the slider, a screw rod rotatably connected to the inside of the lifting block, and a knob fixedly connected to the outside of the screw rod, and an ear holder threadedly connected to the inside of the lifting block;

[0014] Wherein, the lifting block is threadedly connected to the screw rod.

[0015] The present invention also provides a CyberKnife animal treatment fixation device.

[0016] In order to solve the above technical problems, the present invention also provides the following technical solutions: a CyberKnife animal treatment fixation device, comprising the above positioning mechanism, as well as a supporting mechanism, a clamping mechanism and a covering mechanism;

[0017] The clamping mechanism and the covering mechanism are adapted to be installed outside the supporting mechanism, the supporting mechanism is used to place the animal receiving treatment, and the clamping mechanism and the covering mechanism are used to fix the animal receiving treatment.

[0018] As a preferred solution of the CyberKnife animal treatment fixation device of the present invention, the support mechanism includes a support plate fixedly connected to the outside of the end connection block, and an arc groove opened inside the support plate.

[0019] As a preferred solution of the CyberKnife animal treatment fixation device of the present invention, the clamping mechanism includes a clamping block slidably connected to the outer side of the support plate, and a pull ring fixedly connected to the outer side of the clamping block.

[0020] As a preferred solution of the CyberKnife animal treatment fixation device of the present invention, the covering mechanism includes a cylinder fixedly connected to the outside of the arc-shaped groove, and a buckle fixedly connected to the outside of the arc-shaped groove.

[0021] As a preferred solution of the CyberKnife animal treatment fixation device of the present invention, wherein: the covering mechanism further comprises a rotating shaft rotatably connected to the inside of the cylinder, and a film arranged on the outside of the rotating shaft;

[0022] Among them, one end of the film is fixedly connected to the outside of the rotating shaft, and the other end of the film is fixedly connected to a cylinder, and the rotating shaft and the cylinder are connected through a torsion spring.

[0023] The beneficial effects of the present invention are as follows: through the mutual cooperation of various components, the head and body of the animal can be stably fixed, and atomized anesthesia is used instead of injection anesthesia to reduce harm to the animal. After the animal body is fixed, the design of the clamp covering the top of the buckle can reduce the unstable fixation caused by the failure of the buckle, and further enhance the stability of the fixation of the device. BRIEF DESCRIPTION OF THE DRAWINGS

[0024] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the following briefly introduces the drawings required for describing the embodiments. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without creative work. Among them:

[0025] Figure 1 It is an overall schematic diagram of the present invention.

[0026] Figure 2 It is a schematic diagram of the main components of the present invention.

[0027] Figure 3 It is a schematic diagram of the auxiliary components of the present invention.

[0028] Figure 4 It is a schematic diagram of the support mechanism of the present invention.

[0029] Figure 5 It is a cross-sectional schematic diagram of the covering mechanism of the present invention. DETAILED DESCRIPTION

[0030] In order to make the above-mentioned objects, features and advantages of the present invention more obvious and easy to understand, the specific implementation methods of the present invention are described in detail below in conjunction with the accompanying drawings.

[0031] In the following description, many specific details are set forth to facilitate a full understanding of the present invention, but the present invention may also be implemented in other ways different from those described herein, and those skilled in the art may make similar generalizations without violating the connotation of the present invention. Therefore, the present invention is not limited to the specific embodiments disclosed below.

[0032] Secondly, the term "one embodiment" or "embodiment" as used herein refers to a specific feature, structure, or characteristic that may be included in at least one implementation of the present invention. The term "in one embodiment" that appears in different places in this specification does not necessarily refer to the same embodiment, nor does it refer to a separate or selective embodiment that is mutually exclusive with other embodiments.

[0033] Example 1

[0034] Reference Figure 1 and Figure 2, is the first embodiment of the present invention, which provides a positioning mechanism, including:

[0035] The main body component 100 includes an end connection block 101, an anesthesia component 102 adapted to be installed outside the end connection block 101, and an auxiliary component 103 adapted to be installed outside the end connection block 101;

[0036] The anesthesia component 102 is used to anesthetize the animal receiving treatment, and the auxiliary components 103 are symmetrically arranged in two groups, and the auxiliary components 103 are used to fix the head of the animal receiving treatment.

[0037] Specifically, the anesthesia component 102 includes a catheter 102a adapted to be installed inside the end connection block 101, and an incisor holder 102b adapted to be installed at one end of the catheter 102a.

[0038] Furthermore, the anesthesia component 102 also includes a liquid medicine pool 102c adapted to be installed at the other end of the catheter 102a, and a microporous piezoelectric atomizer 102d adapted to be installed inside the liquid medicine pool 102c;

[0039] A top cover for sealing is provided on the top of the liquid medicine pool 102c.

[0040] When in use, the mouth and nose of the animal are placed inside the incisor holder 102b, and the microporous piezoelectric atomizer 102d atomizes the anesthetic agent inside the drug pool 102c and transmits it to the mouth and nose of the animal through the catheter 102a and the incisor holder 102b, thereby anesthetizing the animal.

[0041] Compared with injection anesthesia, this type of atomized inhalation anesthesia can reduce harm to experimental animals.

[0042] Example 2

[0043] Reference Figure 1 to Figure 3 , which is the second embodiment of the present invention. Different from the previous embodiment, this embodiment provides an auxiliary component 103 including a support block 103a fixedly connected to the outside of the end connection block 101, and a slider 103b slidably connected to the inside of the support block 103a.

[0044] Specifically, the auxiliary component 103 also includes a lifting block 103c slidably connected to the inside of the slider 103b, a screw rod 103d rotatably connected to the inside of the lifting block 103c, and a knob 103e fixedly connected to the outside of the screw rod 103d, and an ear holder 103f threadedly connected to the inside of the lifting block 103c;

[0045] The lifting block 103c is threadedly connected to the screw rod 103d.

[0046] Furthermore, by sliding the slider 103b, the position of the slider 103b inside the supporting block 103a can be adjusted.

[0047] The screw rod 103d can be driven to rotate by rotating the knob 103e, thereby adjusting the height of the lifting block 103c.

[0048] By rotating the ear fixer 103f, the position of the ear fixer 103f can be adjusted under the effect of the threaded connection between the ear fixer 103f and the lifting block 103c.

[0049] Through the above three position adjustments, the ear fixer 103f can be adjusted to align with the animal's cochlea, and the animal's ear can be fixed by the ear fixer 103f. Combined with the fixing effect of the incisor fixer 102b, the animal's head can be effectively fixed.

[0050] In addition, gold marks are provided at the ends of the incisor fixer 102b and the ear fixer 103f to cooperate with the CyberKnife's body surface gold mark tracking system to improve the accuracy of positioning and treatment.

[0051] Example 3

[0052] Reference Figure 1 to Figure 5 , which is the third embodiment of the present invention. Different from the previous embodiment, this embodiment provides a CyberKnife animal treatment fixation device, including a positioning mechanism, a supporting mechanism 200, a clamping mechanism 300 and a covering mechanism 400;

[0053] The clamping mechanism 300 and the covering mechanism 400 are adapted to be installed outside the supporting mechanism 200. The supporting mechanism 200 is used to place the animal to be treated, and the clamping mechanism 300 and the covering mechanism 400 are used to fix the animal to be treated.

[0054] Specifically, the supporting mechanism 200 includes a supporting plate 201 fixedly connected to the outside of the end connecting block 101 , and an arc-shaped groove 202 opened inside the supporting plate 201 .

[0055] Furthermore, the clamping mechanism 300 includes a clamping block 301 slidably connected to the outside of the support plate 201 , and a pull ring 302 fixedly connected to the outside of the clamping block 301 .

[0056] More specifically, the covering mechanism 400 includes a cylinder 401 fixedly connected to the outside of the arc-shaped groove 202 , and a buckle 402 fixedly connected to the outside of the arc-shaped groove 202 .

[0057] Furthermore, the covering mechanism 400 further includes a rotating shaft 403 rotatably connected to the inside of the cylinder 401 , and a film 404 disposed outside the rotating shaft 403 ;

[0058] One end of the film 404 is fixedly connected to the outside of the rotating shaft 403, and the other end of the film 404 is fixedly connected to the cylinder 405. The rotating shaft 403 and the cylinder 401 are connected via a torsion spring.

[0059] The buckle 402 is made of elastic material.

[0060] When in use, the animal is placed inside the arc groove 202. The arc groove 202 conforms to the physiological curve of the animal's spine, and the inner wall is covered with a soft cushion layer of silicone or rubber material to reduce the pressure and potential damage to the animal during fixation.

[0061] By pulling the cylinder 405, the cylinder 405 drives the film 404 to extend out from the inside of the cylinder 401 and causes the rotating shaft 403 to rotate.

[0062] Since the buckle 402 is made of elastic material, the cylinder 405 can be snapped into the buckle 402, so that the film 404 covers the surface of the animal and fixes the animal body. The film 404 is designed to cover the animal-specific bio-friendly material film and has a certain elasticity and ductility.

[0063] After the film 404 is covered, the two clamping blocks 301 are pushed toward each other by the pull ring 302, thereby clamping and fixing the animal body.

[0064] When the two clamping blocks 301 approach each other, the bottom of the clamping block 301 will cover the top of the film 404. Figure 5 As shown, the film 404 can cover the surface of the animal more tightly, thereby improving stability.

[0065] Since the rotating shaft 403 and the cylinder 401 are connected by a torsion spring, after the film 404 extends out of the cylinder 401, the film 404 tends to return to its original position due to the resilience of the torsion spring. Therefore, the buckle 402 may fail, causing the cylinder 405 to detach from the buckle 402, thereby affecting the treatment process.

[0066] Because after the two clamping blocks 301 are close to each other, the bottom of the clamping block 301 will cover the top of the buckle 402, so when the cylinder 405 is separated from the fixation of the buckle 402, it will be blocked by the bottom of the clamping block 301, making it difficult for the cylinder 405 to separate from the fixation of the buckle 402, thereby making the fixation of the entire device more stable.

[0067] In addition, the bottom corners of the clamp block 301 are provided with rounded chamfers to reduce the damage to the film 404 caused by the clamp block 301 .

[0068] After the treatment is completed, the two clamps 301 are separated to the initial position, and the cylinder 405 is taken out from the buckle 402. Under the action of the torsion spring between the rotating shaft 403 and the cylinder 401, the film 404 can be automatically rolled up and reset to the inside of the cylinder 401.

[0069] In summary, through the cooperation of various components, the head and body of the animal can be stably fixed, and atomized anesthesia can be used instead of injected anesthesia to reduce harm to the animal. After fixing the animal's body, the design of the clamp block 301 covering the top of the buckle 402 can reduce the unstable fixation caused by the failure of the buckle 402, thereby further enhancing the stability of the fixation of the device.

Claims

1. A positioning mechanism, characterized in that: include, A main body component (100) comprising an end connection block (101), an anesthesia component (102) adapted to be installed outside the end connection block (101), and an auxiliary component (103) adapted to be installed outside the end connection block (101); The anesthesia component (102) is used to anesthetize the animal receiving treatment, and the auxiliary components (103) are symmetrically arranged in two groups, and the auxiliary components (103) are used to fix the head of the animal receiving treatment.

2. The positioning mechanism according to claim 1, characterized in that: The anesthesia component (102) comprises a catheter (102a) adapted to be installed inside the end connection block (101), and an incisor holder (102b) adapted to be installed at one end of the catheter (102a).

3. The positioning mechanism according to claim 2, characterized in that: The anesthesia component (102) further comprises a liquid medicine pool (102c) adapted to be installed at the other end of the catheter (102a), and a microporous piezoelectric atomizer (102d) adapted to be installed inside the liquid medicine pool (102c); Wherein, a top cover for sealing is arranged on the top of the medicine liquid pool (102c).

4. The positioning mechanism according to claim 3, characterized in that: The auxiliary component (103) comprises a support block (103a) fixedly connected to the outside of the end connection block (101), and a sliding block (103b) slidably connected to the inside of the support block (103a).

5. The positioning mechanism according to claim 4, characterized in that: The auxiliary component (103) further comprises a lifting block (103c) slidably connected to the inside of the slider (103b), a screw rod (103d) rotatably connected to the inside of the lifting block (103c), and a knob (103e) fixedly connected to the outside of the screw rod (103d), and an ear holder (103f) threadedly connected to the inside of the lifting block (103c); Wherein, the lifting block (103c) is threadedly connected to the screw rod (103d).

6. A CyberKnife animal treatment fixation device, characterized in that: A positioning mechanism for implementing any one of claims 1 to 5, as well as a supporting mechanism (200), a clamping mechanism (300) and a covering mechanism (400); The clamping mechanism (300) and the covering mechanism (400) are adapted to be installed outside the supporting mechanism (200); the supporting mechanism (200) is used to place the animal to be treated; and the clamping mechanism (300) and the covering mechanism (400) are used to fix the animal to be treated.

7. The CyberKnife animal treatment fixation device according to claim 6, characterized in that: The supporting mechanism (200) comprises a supporting plate (201) fixedly connected to the outside of the end connecting block (101), and an arc-shaped groove (202) provided inside the supporting plate (201).

8. The CyberKnife animal treatment fixation device according to claim 7, characterized in that: The clamping mechanism (300) comprises a clamping block (301) slidably connected to the outside of the support plate (201), and a pull ring (302) fixedly connected to the outside of the clamping block (301).

9. The CyberKnife animal treatment fixation device according to claim 7 or 8, characterized in that: The covering mechanism (400) comprises a cylinder (401) fixedly connected to the outside of the arc-shaped groove (202), and a buckle (402) fixedly connected to the outside of the arc-shaped groove (202).

10. The CyberKnife animal treatment fixation device according to claim 9, characterized in that: The covering mechanism (400) further comprises a rotating shaft (403) rotatably connected to the inside of the cylinder (401), and a film (404) arranged on the outside of the rotating shaft (403); One end of the film (404) is fixedly connected to the outside of the rotating shaft (403), and the other end of the film (404) is fixedly connected to a cylinder (405). The rotating shaft (403) and the cylinder (401) are connected via a torsion spring.