Structure for grabbing slice sample carrying net and microscope system

By designing a structure for grasping slice sample web including a clamping frame, clamping jaw, movable arm and driving mechanism, the problem of low loading efficiency of manual sample web is solved, and efficient, stable and reliable sample web gripping is achieved, which improves experimental efficiency and reduces costs.

CN119871367APending Publication Date: 2025-04-25BIOISLAND LAB
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Patent Information

Application Number
CN202510046495.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-01-10
Publication Date
2025-04-25

AI Technical Summary

Technical Problem

In the prior art, manual sample picking is low in network loading efficiency, resulting in a decrease in sample quality, low experimental efficiency and improved cost.

Method used

A structure for grabbing sliced ​​sample loading is designed, including a clamping frame, clamping jaws, movable arms and drive mechanisms, and the clamping jaws are driven to close or open to grab the sample loading mesh through the drive mechanism and movable arms.

Benefits of technology

It realizes efficient, stable and reliable sample web-mounted grabbing, improves experimental efficiency, reduces costs, and has stable structure, high repeatability, small wear rate, and is easy to maintain.

✦ Generated by Eureka AI based on patent content.

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Abstract

The invention relates to a structure for grabbing a slice sample carrying net and a microscope system. The structure comprises a clamping frame, a clamping jaw, a movable arm and a driving mechanism, the clamping jaw comprises a static jaw and a movable jaw, the static jaw is arranged on the clamping frame, the rear end of the movable jaw is pivoted with the rear end of the static jaw through a pivoting piece, a static clamping part is arranged at the front end of the static jaw, and a movable clamping part is arranged at the front end of the movable jaw; the front end of the movable arm is fixedly connected with the rear end of the movable claw, and a driving part is arranged at the rear end of the movable arm; the driving mechanism is arranged on the clamping frame and connected with the driving part so as to drive the movable arm to drive the movable claw to rotate. The clamping jaws are driven to be closed or opened through the driving mechanism and the movable arm so as to grab the sample carrying net, the structure is stable and reliable, repeatability is high, the abrasion rate is small, later maintenance is easy, and mechanical operation is achieved through the driving mechanism.
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Description

Technical Field

[0001] The invention relates to the technical field of microscopes, and in particular to a structure for grabbing a slice sample carrier grid and a microscope system. Background Art

[0002] The rapid development of electron microscopy imaging technology has made it possible to conduct high-resolution three-dimensional structural analysis of intact cells, tissues, and even the entire body. These electron microscopy imaging technologies that can conduct large-scale three-dimensional structural research on biological samples are collectively referred to as volume electron microscopy (vEM). In recent years, vEM has developed rapidly in terms of research scale, resolution, throughput, and ease of use, and its application in the entire life science field has exploded. TEM-based vEM imaging technology, serial section transmission electron microscopy (ssTEM), is the earliest but the latest technology to develop among the three major vEM technologies. Unlike the dual-beam technology of focused ion beam / scanning electron microscopy (FIB-SEM) and the automated system of block face scanning electron microscopy (SBF-SEM), ssTEM has significant advantages such as fast high resolution and fast imaging. However, the development of this technology is currently mainly limited by several aspects such as high-throughput sample preparation and loading, continuous data acquisition, and subsequent data processing algorithms.

[0003] At present, the basic method of grabbing sample grids is to manually grab 1 to 6 samples and place them on the sample stage. Since a complete ssTEM experiment requires at least 500 samples, manually changing samples will take a lot of time and manpower. The experimental data collection cycle of years will reduce the sample quality, reduce the experimental efficiency and greatly increase the cost.

[0004] Therefore, there is an urgent need for a structure for grabbing a slice sample carrier grid and a microscope system to solve the above technical problems. Summary of the invention

[0005] The purpose of the present invention is to provide a structure for grabbing a slice sample carrier grid, so as to solve the problem of low efficiency of manual operation in the prior art.

[0006] To achieve the above object, one object of the present invention is to provide a structure for grabbing a slice sample carrier net, comprising:

[0007] Gripping rack;

[0008] A clamping jaw, the clamping jaw comprising a stationary jaw and a movable jaw, the stationary jaw being arranged on the clamping frame, the rear end of the movable jaw being pivotally connected to the rear end of the stationary jaw through a pivoting member, the front end of the stationary jaw being provided with a stationary clamping portion, and the front end of the movable jaw being provided with a movable clamping portion;

[0009] A movable arm, the front end of which is fixedly connected to the rear end of the movable claw, and the rear end of the movable arm is provided with a driving part;

[0010] A driving mechanism is arranged on the clamping frame and connected to the driving part to drive the movable arm to drive the movable claw to rotate.

[0011] Preferably, the structure for grabbing the slice sample grid further comprises an elastic member, one end of which is connected to the clamping frame, and the other end of which is connected to the movable arm;

[0012] The clamping jaw is normally closed under the elastic force of the elastic member, and the driving mechanism drives the movable arm to overcome the elastic force of the elastic member to drive the movable jaw to rotate so that the clamping jaw opens.

[0013] Preferably, the elastic member is a compression spring.

[0014] Preferably, the clamping claw further comprises a fixing arm, and the fixing arm is detachably connected to the clamping frame via a first screw; and an end of the fixing arm is connected to the stationary claw.

[0015] Preferably, the fixed arm has a movable arm space, and the movable arm can be at least partially embedded in the fixed arm.

[0016] Preferably, the pivot member includes a pivot seat and a pivot shaft, the rear end of the stationary claw is fixed to the pivot seat, the pivot shaft is arranged on the pivot seat, and the rear end of the movable claw is rotatably mounted with the pivot seat via the pivot shaft.

[0017] Preferably, the movable claw is connected to the pivot shaft via a ball bearing.

[0018] Preferably, the clamping frame includes a front frame section and a rear frame section, the rear frame section is provided with a mounting groove, the front frame section is provided with a front opening, the front opening is connected to the mounting groove, the driving mechanism is installed in the mounting groove, the fixed arm passes through the front opening and is installed on the front frame section, and the movable arm passes through the front opening and is connected to the driving mechanism.

[0019] Preferably, the static clamping portion is provided with a static clamping positioning portion.

[0020] Preferably, the movable claw comprises a movable claw body and a movable clamping member detachably mounted on the movable claw body, and the movable clamping portion is arranged at the front end of the movable clamping member.

[0021] Preferably, the dynamic clamp is provided with a plurality of dynamic clamp hooks.

[0022] Preferably, the driving mechanism includes a motor and a cam, the motor is fixed to the clamping frame, the motor has a rotating shaft, the cam is arranged on the rotating shaft, the cam has a first protrusion, and the motor is used to drive the rotating shaft to rotate to switch the first protrusion to be in abutment connection with the driving part or not, and when the first protrusion is in abutment connection with the driving part, the clamping jaw opens.

[0023] Preferably, the motor is fixed to the clamping frame by a third screw.

[0024] Preferably, the motor is provided with a control module, and the control module is used to receive an external control signal and execute the external control signal.

[0025] Preferably, the control module is provided with a wireless receiving element.

[0026] Another object of the present invention is a microscope system, comprising a microscope and the structure of the grid for grabbing and sectioning samples as described above.

[0027] Preferably, it further comprises a sample grid, wherein the sample grid is used to carry the sample, and the dynamic clamping part and the static clamping part of the structure for grabbing and slicing the sample grid are used to clamp the sample grid.

[0028] Preferably, the sample grid is provided with an identification area, and the identification area is provided with a QR code and / or a bar code.

[0029] Preferably, the sample grid has a thickness of 80 to 100 microns.

[0030] As can be seen from the above, the technical solution provided by the present invention is a structure for grabbing the slice sample carrier, which drives the clamping claws to close or open to grab the sample carrier through a driving mechanism and a movable arm. The structure is stable and reliable, has high repeatability, low wear rate, and is easy for later maintenance and servicing. The driving mechanism is used to achieve mechanized operation, which is more efficient than the manual operation in the prior art. BRIEF DESCRIPTION OF THE DRAWINGS

[0031] Figure 1 A three-dimensional diagram of a structural embodiment of a grid for grabbing sliced ​​samples according to the present invention;

[0032] Figure 2 It is a front view of a structural embodiment of a grid for grabbing sliced ​​samples according to the present invention;

[0033] Figure 3 The invention is a structural embodiment of a grid for grabbing sliced ​​samples. Figure 2 Sectional view in the AA direction (closed);

[0034] Figure 4 A cross-sectional view (opened) of a structural embodiment of a grid for grabbing sliced ​​samples according to the present invention;

[0035] Figure 5 The present invention is a structural embodiment of a grid for grabbing slice samples Figure 4 Enlarged view of part I;

[0036] Figure 6 A three-dimensional diagram of a clamping frame for grabbing a slice sample carrier net according to a structural embodiment of the present invention;

[0037] Figure 7 A three-dimensional diagram of a driving mechanism of a structural embodiment of the present invention for grabbing a slice sample carrier net;

[0038] Figure 8 A three-dimensional diagram of a clamping claw and a movable arm of a structural embodiment of the present invention for grabbing a slice sample carrier net;

[0039] Fig. 9 A front view of a sample grid of an embodiment of a microscope system of the present invention.

[0040] In the figure:

[0041] 100, clamping frame; 110, front frame section; 111, front opening; 120, rear frame section; 121, mounting slot;

[0042] 200, clamping jaw; 210, stationary jaw; 211, stationary clamping positioning portion; 2101, stationary clamping portion; 220, movable jaw; 221, movable jaw body; 222, movable clamping member; 2221, movable clamping hook; 223, second screw; 2201, movable clamping portion; 230, pivoting member; 231, pivoting seat; 232, pivoting shaft; 233, rolling bearing; 240, fixed arm; 241, first screw;

[0043] 300, movable arm; 310, driving part; 320, spring slot;

[0044] 400, driving mechanism; 410, motor; 411, rotating shaft; 420, cam; 421, first protrusion; 430, third screw;

[0045] 500, elastic parts;

[0046] 600, sample grid; 610, identification area. DETAILED DESCRIPTION

[0047] The technical solution of the present invention is further described below in conjunction with the accompanying drawings and through specific implementation methods. It is understood that the specific embodiments described herein are only used to explain the present invention, rather than to limit the present invention. It is also necessary to explain that, for ease of description, only the parts related to the present invention are shown in the accompanying drawings, rather than all.

[0048] Some directional words are defined in the present invention. Unless otherwise specified, the directional words used, such as "up", "down", "left", "right", "inside" and "outside", are used to facilitate understanding and therefore do not constitute a limitation on the scope of protection of the present invention.

[0049] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may include that the first and second features are in direct contact, or may include that the first and second features are not in direct contact but are in contact through another feature between them. Moreover, a first feature being "above", "above" and "above" a second feature includes that the first feature is directly above and obliquely above the second feature, or simply indicates that the first feature is higher in level than the second feature. A first feature being "below", "below" and "below" a second feature includes that the first feature is directly below and obliquely below the second feature, or simply indicates that the first feature is lower in level than the second feature.

[0050] In the description of the present invention, unless otherwise clearly specified and limited, the terms "connected", "connected", and "fixed" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.

[0051] Reference Figures 1 to 8 As shown, this embodiment provides a preferred implementation of a structure for grabbing a slice sample grid. The structure for grabbing a slice sample grid includes a clamping frame 100, a clamping claw 200, a movable arm 300 and a driving mechanism 400.

[0052] The clamping frame 100 is preferably made of metal material, such as aluminum alloy, titanium alloy or stainless steel. The clamping frame 100 is used to install the clamping jaws 200 and the driving mechanism 400, and is also used to install the structure for grabbing the slice sample grid to the transfer component of the microscope system. The transfer component of the microscope system grabs the sample grid through the structure for grabbing the slice sample grid and transfers the sample grid.

[0053] The clamping jaw 200 includes a stationary jaw 210 and a movable jaw 220. The stationary jaw 210 is arranged on the clamping frame 100, and the rear end of the movable jaw 220 is pivotally connected to the rear end of the stationary jaw 210 through a pivoting member 230. A stationary clamping portion 2101 is arranged at the front end of the stationary jaw 210, and a movable clamping portion 2201 is arranged at the front end of the movable jaw 220. When the movable jaw 220 rotates so that the movable clamping portion 2201 approaches the stationary clamping portion 2101, the clamping jaw 200 is closed to clamp the sample carrier net; when the movable jaw 220 rotates so that the movable clamping portion 2201 is away from the stationary clamping portion 2101, the clamping jaw 200 is opened to release the sample carrier net. The stationary jaw 210 can be installed on the clamping frame 100 by mechanical connection methods such as welding, bonding, integral molding connection or screw connection.

[0054] The front end of the movable arm 300 is fixedly connected to the rear end of the movable claw 220, and the rear end of the movable arm 300 is provided with a driving part 310. The movable arm 300 is used to drive the movable claw 220 to rotate around the pivot 230 under the drive of an external power, thereby closing or opening the movable clamping part 2201 and the static clamping part 2101, and realizing the action of clamping or releasing the sample carrier net.

[0055] The driving mechanism 400 is disposed on the clamping frame 100 and connected to the driving part 310 to drive the movable arm 300 to drive the movable claw 220 to rotate. The driving mechanism 400 is used to provide external power. The movable arm 300 uses the principle of a lever structure, and the pivot 230 is used as a pivot fulcrum. The movable arm 300 drives the movable claw 220 of the clamp 200 to rotate around the pivot 230. The driving mechanism 400 can be a cylinder mechanism or a servo motor mechanism.

[0056] The structure of grabbing the slice sample grid of the present invention drives the clamping jaws 200 to close or open to grab the sample grid through the driving mechanism 400 and the movable arm 300. The structure is stable and reliable, with high repeatability, low wear rate, and easy later maintenance. The driving mechanism 400 is used to realize mechanized operation, which is more efficient than the manual operation in the prior art.

[0057] Further, such as Figure 3 and 4As shown, the structure for grabbing the slice sample carrier net also includes an elastic member 500. One end of the elastic member 500 is connected to the clamping frame 100, and the other end of the elastic member 500 is connected to the movable arm 300. Under the elastic force of the elastic member 500, the clamping jaw 200 is normally closed, and the driving mechanism 400 drives the movable arm 300 to overcome the elastic force of the elastic member 500 and drive the movable claw 220 to rotate so that the clamping jaw 200 is opened. In this embodiment, the elastic member 500 is preferably a compression spring, one end of the elastic member 500 is elastically abutted and connected to the clamping frame 100, and the other end of the elastic member 500 is elastically abutted and connected to the movable arm 300. When there is no other external force acting on the movable arm 300, only under the elastic force of the elastic member 500, the movable clamping portion 2201 of the movable claw 220 is statically maintained in a state close to the static clamping portion 2101, and at this time, the clamping jaw 200 is in a closed state, that is, the clamping jaw 200 is in a normally closed state under the action of the elastic member. As shown in the figure, if the clamping jaws are to be opened, the driving mechanism 400 is used to overcome the elastic force of the elastic member 500, drive the movable arm 300 to rotate, the movable jaw 220 to rotate, and the movable clamping portion 2201 to move away from the static clamping portion 2101, thereby opening the clamping jaw 200. As shown in the figure, the elastic member 500 is supported at a position of the movable arm 300 close to the driving portion 310, and under the action of the elastic potential energy, the movable jaw is in a normally closed state.

[0058] Preferably, Figure 3 , 4 As shown in FIG. 8 , the movable arm 300 is provided with a spring slot 320 , one end of the elastic member 500 is mounted on the clamping frame 100 , and the other end of the elastic member 500 is mounted on the spring slot 320 . The elastic member 500 is limited by the spring slot 320 , which facilitates the installation and removal of the elastic member. Figure 3 and 4 As shown, a spring base is provided on the clamping frame 100 for mounting the elastic member 500 .

[0059] The structure for grabbing the slice sample grid is transferred after clamping the sample grid. When the power of the driving mechanism 400 is used to keep the clamping jaws 200 in a closed clamping state, the clamping jaws 200 are in a rigid clamping state. During the transfer process, vibration is often generated. If the power provided by the driving mechanism 400 is too large, it is easy to damage the sample grid. If the power provided by the driving mechanism 400 is too small, it is easy to cause the sample grid to fall off. Therefore, the present invention further provides an elastic member 500 in the structure for grabbing the slice sample grid. When the clamping jaws 200 are kept in a closed clamping state under the elastic force of the elastic member 500, the elastic force of the elastic member 500 has the advantage of continuous stability, and the clamping force will not be too large or too small, thereby reducing the risk of damage or loosening of the sample grid. At the same time, the influence of mechanical vibration in the process of transferring the sample grid by the structure for grabbing the slice sample grid will at least be partially offset by the elastic potential energy of the elastic member 500, and it has good clamping stability.

[0060] Further, such as Figure 3 , 4 As shown in FIG. 8 , the clamping jaw 200 further includes a fixed arm 240, which is detachably connected to the clamping frame 100 via a first screw 241, and the end of the fixed arm 240 is connected to the stationary jaw 210. Thus, the stationary jaw 210 is fixedly connected to the clamping frame 100 via the fixed arm 240. The clamping jaw 200 is detachably mounted on the clamping frame 100 using the first screw 241. When the clamping jaw 200 is damaged, a different clamping jaw 200 can be replaced, or a clamping jaw 200 of different models can be replaced according to different sample carrier nets. The special first screw 241 is used to lock and fix, so as to avoid vibration generated during the grasping process.

[0061] Further, such as Figure 1 , 3 , 4 and 8, the pivot member 230 includes a pivot seat 231 and a pivot shaft 232. The rear end of the stationary claw 210 is fixed to the pivot seat 231, and the pivot shaft 232 is disposed on the pivot seat 231. The rear end of the movable claw 220 is rotatably mounted on the pivot seat 231 via the pivot shaft 232. Specifically, the pivot seat 231 is a U-shaped structure, and the pivot shaft is mounted on two arms of the pivot seat 231. The stationary claw 210 and the fixed arm 240 are both fixedly connected to the pivot seat 231.

[0062] like Figure 8 As shown, the fixed arm 240 has a movable arm space, and the movable arm 300 can be at least partially embedded in the fixed arm 240. The fixed arm 240 has a movable arm space for accommodating a movable arm, which is used to accommodate part of the movable arm 300. When the movable arm 300 is close to the fixed arm 240, the movable arm 300 can be at least partially accommodated in the movable arm space. The movable arm space of the fixed arm 240 makes the structure compact.

[0063] Further, such as Figure 3 , 4 As shown, the movable claw 220 is connected to the pivot shaft 232 via a ball bearing 233. By using the ball bearing 233 as a pivot rotation fit, the clamping of the clamping claw 200 is more stable and the error is reduced.

[0064] like Figure 1 , 3, 4 and 6, in this embodiment, the clamping frame 100 includes a front frame section 110 and a rear frame section 120, the rear frame section 120 is provided with a mounting slot 121, the front frame section 110 is provided with a front opening 111, the front opening 111 is connected to the mounting slot 121, the driving mechanism 400 is installed in the mounting slot 121, the fixed arm 240 passes through the front opening 111 and is installed on the front frame section 110, and the movable arm 300 passes through the front opening 111 and is connected to the driving mechanism 400. Specifically, the driving mechanism 400 is arranged in the mounting slot 121, and the rear end of the movable arm 300 passes through the front opening 111, so that the driving part 310 is connected to the driving mechanism 400. Both the front frame section 110 and the fixed arm 240 are provided with a first screw hole matched with the first screw 241. After the fixed arm 240 passes through the front opening 111, the first screw 241 is screwed into the outer wall of the front frame section 110 to fix the front frame section 110 and the fixed arm 240.

[0065] Further, such as Figure 1 , 3 , 4 and 6, the diameter of the pivot seat 231 is larger than the diameter of the front opening 111, so as to be clamped on the front end surface of the front opening 111. The pivot seat 231 plays a positioning role, and different sizes of clamping jaws 200 can be set, which is convenient for replacing the clamping jaws 200 according to different sample grid requirements.

[0066] like Figure 1 , 3 As shown in , 4 and 6, the static clamping portion 210 is provided with a static clamping positioning portion 211, which is used to position the clamped sample carrier net so that the sample carrier net is accurately clamped. In this embodiment, the static clamping positioning portion 211 is two static clamping positioning columns extending from the surface of the static clamping portion 2101 and arranged at intervals.

[0067] like Figure 1 , 3 As shown in FIGS. 4 and 6, the movable claw 220 includes a movable claw body 221 and a movable clamping member 222 detachably mounted on the movable claw body 221, and the movable clamping portion 2201 is disposed at the front end of the movable clamping member 222. The movable claw 220 is configured as a movable claw body 221 and a movable clamping member 222, and the movable clamping member 222 is detachably connected to the movable claw body 221 by a second screw 223. The appropriate movable clamping member 222 can be replaced as needed, and the structure for grabbing the slice sample carrier network has a wider applicability.

[0068] like Figure 5 and 8 As shown, the movable clamping member 222 is provided with a plurality of movable clamping hooks 2221. As shown in the figure, the movable clamping member 222 is provided with two movable clamping hooks 2221, and the two movable clamping hooks 2221 are arranged at intervals. The movable clamping hooks 2221 are provided to achieve point contact during clamping, and have better clamping performance.

[0069] Further, such as Figure 1 ,3 , 4 and 7, in this embodiment, the driving mechanism 400 is a servo motor mechanism. The driving mechanism 400 includes a motor 410 and a cam 420. The motor 410 is fixed to the clamping frame 100. The motor 410 has a rotating shaft 411. The cam 420 is arranged on the rotating shaft 410. The cam 420 has a first protrusion 421. The motor 410 is used to drive the rotating shaft 411 to rotate to switch the first protrusion 421 to abut or not abut with the driving part 310. When the first protrusion 421 is abutted and connected with the driving part 310, the clamping jaw 200 is opened; when the first protrusion 421 is not abutted and connected with the driving part 310, the clamping jaw 200 is in a normally closed state. When the structure for grabbing the slice sample network clamps the sample network, the motor 410 works so that the first protrusion 421 of the cam 420 abuts against the driving part 310, and the movable arm 300 rotates with the movable claw 220, thereby opening the clamping claw 200; when the sample network enters between the dynamic clamping part 2201 and the static clamping part 2101, the motor 410 works, the first protrusion 421 of the cam 420 is not abutted and connected with the driving part 310, the elastic potential energy of the elastic member 500 is converted into an upward force, and the clamping claw 200 closes to clamp the sample network, thereby achieving the grabbing of the sample network.

[0070] Exemplarily, in this embodiment, the cam 420 is an eccentric wheel, that is, the cam 420 is an eccentrically mounted disc, so that a first protrusion 421 is formed on a side of the disc away from the rotating shaft 411 .

[0071] like Figure 3 and 4 As shown, the motor 410 is fixed to the clamping frame 100 by a third screw 430 . A third screw hole is provided at the bottom of the mounting groove 121 , and the motor 410 is mounted on the bottom surface of the mounting groove 121 by the third screw 430 .

[0072] The motor 410 is provided with a control module (not shown), which is used to receive external control signals and execute the external control signals. The motor 410 is preferably a stepping motor. Under the control of the control module, the shaft of the motor 410 rotates half a circle each time, so that the first protrusion is in abutment connection with the driving part 310 or not, thereby switching the opening or closing state of the clamping jaw 200.

[0073] Preferably, the control module is provided with a receiving element, and the receiving element can use a wired receiving element or a wireless receiving element. In this embodiment, the control module is provided with a wireless receiving element, and the control signal is received through the wireless receiving element, thereby reducing the complexity of wiring.

[0074] The present invention further provides a microscope system, comprising a microscope and the structure of the grid for grabbing and slicing sample of the above embodiment.

[0075] like Figure 1 , 2As shown in , 3, 4 and 9, the microscope system also includes a sample grid 600, which is used to carry samples. The dynamic clamping part 2201 and the static clamping part 2101 of the structure for grabbing and slicing the sample grid are used to clamp the sample grid 600.

[0076] like Fig. 9 As shown, the sample grid 600 is provided with an identification area 610, and the identification area 610 is provided with a QR code and / or a barcode. The identification area is provided on the sample grid, and according to the identification information of the identification area, the sample can be automatically loaded and the data can be automatically stored, the processing difficulty is moderate, and the production is easy.

[0077] The thickness of the sample grid 600 is 80 to 100 microns. The structure of the sample grid for grabbing and slicing can grab a single sample grid, which is different from the grabbing method of most devices on the market, and has more flexible options in the experimental process.

[0078] Although the present invention has been described in detail above by means of general description, specific implementation methods and tests, it is obvious to those skilled in the art that some modifications or improvements may be made to the present invention. Therefore, these modifications or improvements made without departing from the spirit of the present invention all fall within the scope of protection claimed by the present invention.

Claims

1. A structure for grabbing a slice sample carrier net, characterized in that: include Gripping rack; A clamping jaw, the clamping jaw comprising a stationary jaw and a movable jaw, the stationary jaw being arranged on the clamping frame, the rear end of the movable jaw being pivotally connected to the rear end of the stationary jaw through a pivoting member, the front end of the stationary jaw being provided with a stationary clamping portion, and the front end of the movable jaw being provided with a movable clamping portion; A movable arm, the front end of which is fixedly connected to the rear end of the movable claw, and the rear end of the movable arm is provided with a driving part; and A driving mechanism is arranged on the clamping frame and connected to the driving part to drive the movable arm to drive the movable claw to rotate.

2. The structure of grabbing and slicing sample carrier network according to claim 1, characterized in that: The structure for grabbing the slice sample carrier net also includes an elastic member, one end of which is connected to the clamping frame, and the other end of which is connected to the movable arm; The clamping jaw is normally closed under the elastic force of the elastic member, and the driving mechanism drives the movable arm to overcome the elastic force of the elastic member to drive the movable jaw to rotate so that the clamping jaw opens.

3. The structure of grabbing and slicing sample carrier network according to claim 2, characterized in that: The elastic member is a compression spring.

4. The structure of grabbing and slicing sample carrier network according to claim 2, characterized in that: The clamping claw further comprises a fixing arm, and the fixing arm is detachably connected to the clamping frame via a first screw; and an end of the fixing arm is connected to the stationary claw.

5. The structure for grabbing and slicing sample carrier net according to claim 4, characterized in that: The fixed arm has a movable arm space, and the movable arm can be at least partially embedded in the fixed arm.

6. The structure for grabbing and slicing sample carrier net according to claim 4, characterized in that: The pivot member comprises a pivot seat and a pivot shaft, the rear end of the stationary claw is fixed to the pivot seat, the pivot shaft is arranged on the pivot seat, and the rear end of the movable claw is rotatably mounted with the pivot seat through the pivot shaft.

7. The structure for grabbing and slicing sample carrier net according to claim 6, characterized in that: The movable claw is connected to the pivot shaft through a ball bearing.

8. The structure for grabbing and slicing sample carrier net according to claim 7, characterized in that: The clamping frame includes a front frame section and a rear frame section, the rear frame section is provided with a mounting groove, the front frame section is provided with a front opening, the front opening is communicated with the mounting groove, the driving mechanism is installed in the mounting groove, the fixed arm passes through the front opening and is installed on the front frame section, and the movable arm passes through the front opening and is connected to the driving mechanism.

9. The structure for grabbing and slicing sample carrier net according to claim 2, characterized in that: The static clamping portion is provided with a static clamping positioning portion.

10. The structure for grabbing a slice sample grid according to claim 2, characterized in that: The movable claw comprises a movable claw body and a movable clamping piece detachably mounted on the movable claw body, and the movable clamping portion is arranged at the front end of the movable clamping piece.

11. The structure for grabbing a slice sample grid according to claim 10, characterized in that: The dynamic clamping member is provided with a plurality of dynamic clamping hooks.

12. The structure for grabbing a slice sample grid according to any one of claims 2 to 11, characterized in that: The driving mechanism includes a motor and a cam, wherein the motor is fixed to the clamping frame, the motor has a rotating shaft, the cam is arranged on the rotating shaft, the cam has a first protrusion, and the motor is used to drive the rotating shaft to rotate to switch the first protrusion to be in abutment connection with the driving part or not in abutment connection. When the first protrusion is in abutment connection with the driving part, the clamping jaw opens.

13. The structure for grabbing a slice sample carrier network according to claim 12, characterized in that: The motor is fixed to the clamping frame by a third screw.

14. The structure for grabbing a slice sample carrier network according to claim 13, characterized in that: The motor is provided with a control module, and the control module is used to receive an external control signal and execute the external control signal.

15. The structure for grabbing a slice sample grid according to claim 14, characterized in that: The control module is provided with a wireless receiving element.

16. A microscope system, characterized in that: The invention comprises a microscope and a structure of a grid for grabbing and slicing sample as claimed in any one of claims 1 to 15.

17. The microscope system according to claim 16, characterized in that It also includes a sample grid, which is used to carry samples. The dynamic clamping part and the static clamping part of the structure for grabbing and slicing the sample grid are used to clamp the sample grid.

18. The microscope system according to claim 17, characterized in that The sample grid is provided with an identification area, and the identification area is provided with a QR code and / or a bar code.

19. The microscope system according to claim 17, characterized in that The thickness of the sample grid is 80 to 100 microns.

Citation Information

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