Herpes zoster virus culture device and culture process

Abstract

The invention relates to the technical field of virus culture, in particular to a herpes zoster virus culture device and a herpes zoster virus culture technology.The herpes zoster virus culture device comprises a device shell, a feeding port is formed in the upper portion of the device shell, a discharging port is formed in the lower portion of the device shell, and a homogenizing bin is fixedly installed in the device shell; the upper end of the homogenate bin is communicated with the feed port, a rotatable centrifugal barrel is arranged in the device shell, the centrifugal barrel is located below the homogenate bin, the centrifugal barrel rotates with the homogenate bin as the circle center through a rotating mechanism, a discharging mechanism is arranged below the homogenate bin, and a crushing mechanism is arranged in the homogenate bin. According to the herpes zoster virus culture device and process, under the cooperation of the rotating mechanism, the centrifugal barrel can rotate with the homogenate bin as the circle center, and the centrifugal barrel can rotate, so that when the centrifugal barrel conducts centrifugal treatment, homogenate samples can be added into the centrifugal barrel at any time, and the centrifugal efficiency can be improved.

Description

Technical Field

[0001] The invention relates to the technical field of virus culture, in particular to a herpes zoster virus culture device and a culture process. Background Art

[0002] Herpes zoster virus culture refers to the extraction of the virus from the patient's rash, blister fluid or other relevant samples, and cultivation under appropriate laboratory conditions to observe the growth and reproduction of the virus, thereby confirming herpes zoster.

[0003] The cultivation and separation of herpes zoster virus mainly rely on cell culture technology. When cultivating herpes zoster virus, samples need to be collected and processed. Generally, the larger tissues in the sample are cut into pieces manually with small scissors, and then homogenized. The homogenized sample also needs to be centrifuged. The above method is only suitable for the laboratory to cultivate herpes zoster virus with a small sample. When a large number of herpes zoster viruses need to be cultivated, the efficiency of the above device is relatively low, and it requires manual and multiple equipment to cooperate, which not only increases the cost of cultivation, but also wastes human resources. Summary of the invention

[0004] The object of the present invention is to provide a herpes zoster virus culture device and culture process to solve the problems raised in the above background technology.

[0005] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a herpes zoster virus culture device, comprising a device shell, a feed port is provided at the top of the device shell, a discharge port is provided at the bottom of the device shell, a homogenization bin is fixedly installed inside the device shell, the upper end of the homogenization bin is connected to the feed port, a rotatable centrifuge barrel is arranged inside the device shell, the centrifuge barrel is located below the homogenization bin, the centrifuge barrel rotates with the homogenization bin as the center through a rotating mechanism, a discharge mechanism is provided below the homogenization bin, and a crushing mechanism is provided inside the homogenization bin.

[0006] Preferably, the rotating mechanism includes a support member and a guide groove, the support member is fixedly mounted on the outside of the centrifuge barrel, the guide groove is opened on the inner wall of the device housing, the guide groove and the support member are rotatably connected, and a driving assembly is arranged below the support member.

[0007] Preferably, the driving assembly includes a No. 1 gear ring, a No. 1 gear and a motor, the motor is fixedly mounted below the device housing, the output end of the motor passes through the device housing and extends to the interior of the device housing, the No. 1 gear is fixedly sleeved outside the output end of the motor, the No. 1 gear ring is fixedly mounted below the support, and the No. 1 gear ring and the No. 1 gear are meshed.

[0008] Preferably, a fixing plate is fixedly installed above the centrifugal barrel, a rotating shaft is fixedly installed above the fixing plate, the rotating shaft rotates through the support member, a No. 2 gear is fixedly sleeved outside the rotating shaft, a No. 2 gear ring is fixedly installed inside the device housing, and the No. 2 gear and the No. 2 gear ring are meshed.

[0009] Preferably, the discharge mechanism includes a filter plate, which is rotatably installed at the bottom of the homogenization bin, an adjustment plate is provided between the filter plate and the support, the adjustment plate is connected to the support through a movable assembly, a slider is fixedly installed above the adjustment plate, a slide groove is provided below the filter plate, and the slide groove and the slider are slidably connected.

[0010] Preferably, the moving assembly includes a cross bar, which is fixedly installed inside the support member, and the cross bar is slidably connected to the adjustment plate. The outer movable sleeve of the cross bar is provided with a No. 1 spring, and the No. 1 spring is fixedly connected to the adjustment plate.

[0011] Preferably, the moving component also includes a No. 1 magnet and a No. 2 magnet, the No. 1 magnet is fixedly mounted on one side of the adjustment plate, the No. 2 magnet is fixedly mounted on the inner wall of the device housing, and the No. 1 magnet and the No. 2 magnet attract each other.

[0012] Preferably, the crushing mechanism includes blades and a shaft, the shaft is slidably inserted into the interior of the homogenization bin through a lifting assembly, the shaft is horizontally arranged, the number of the blades is at least two groups, the blades are rotatably connected to the shaft, the two groups of blades are symmetrically arranged, a movable groove is opened inside the blade, a fixed rod slides through the interior of the movable groove, and the fixed rod is fixedly inserted inside the homogenization bin.

[0013] Preferably, the lifting assembly includes a support block, which is fixedly mounted at both ends of the shaft, and a column is slidably penetrated inside the support block, and the column and the homogenization bin are fixedly connected, and the external movable sleeve of the column is provided with a No. 2 spring, and the No. 2 spring is fixedly connected to the support block, and a protrusion is fixedly mounted above the filter plate, and the protrusion and the support block are in contact and cooperate with each other, and a guide shell is slidably provided on the inner wall of the homogenization bin, and bending blocks are fixedly connected at the edges of the inner top surface of the guide shell, respectively, and a guide opening is provided on the inner wall of the homogenization bin near the upper end of the guide shell, and the end of the bending block is slidably inserted into the inner side of the guide opening, and a top guide surface is provided on the upper end surface of the guide shell, and two symmetrical bending plates are fixedly connected to the lower side of the guide shell, and the lower surface of the bending plate is close to the upper edge of the blade, and the upper end surface of the support block is fixedly connected to the contact column.

[0014] The present invention also provides a herpes zoster virus culture process, comprising the following steps:

[0015] Step 1: Add the sample into the homogenization chamber, break the sample into small pieces by the crushing mechanism and homogenize;

[0016] Step 2: During step 1, the rotating mechanism drives the centrifugal bucket to rotate with the homogenization chamber as the center, so that the homogenized sample can pass through the filter plate and fall into the inside of the centrifugal bucket;

[0017] Step 3: The centrifuge barrel can rotate on its own while rotating with the homogenization chamber as the center, centrifugally treating the sample inside the centrifuge barrel, and the treated sample is discharged from the inside of the device shell through the discharge port.

[0018] Compared with the prior art, the present invention has the following beneficial effects:

[0019] 1. By setting up a homogenization chamber, with the cooperation of the blade, the sample inside the homogenization chamber can be sheared and crushed. Under the action of the filter plate, not only can the sample inside the homogenization chamber be evenly crushed, but also the sample inside the homogenization chamber can be homogenized, which is beneficial to improve the efficiency of homogenization.

[0020] 2. By setting a movable adjustment plate, with the cooperation of magnet No. 1 and magnet No. 2, the adjustment plate is moved away from the bottom of the homogenization chamber, and the homogenized sample inside the homogenization chamber can fall into the centrifuge barrel. When the adjustment plate returns to the bottom of the homogenization chamber, the sample is always located inside the homogenization chamber, so that the sample inside the homogenization chamber can be processed, which is convenient for sufficient homogenization of the sample.

[0021] 3. By setting up a centrifugal bucket, with the cooperation of the rotating mechanism, the centrifugal bucket can rotate with the homogenization chamber as the center, and the centrifugal bucket can rotate on its own, so that when the centrifugal bucket is centrifuged, the homogenized sample can be added to the inside of the centrifugal bucket at any time, which is beneficial to improve the efficiency of centrifugation. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a schematic diagram of the overall structure of the present invention;

[0023] Figure 2 It is a structural cross-sectional view of the present invention;

[0024] Figure 3 It is a partial structural cross-sectional view of the present invention;

[0025] Figure 4 A cross-sectional view of the upper end of the housing of the device of the present invention;

[0026] Figure 5 For the present invention Figure 4 A magnified image of point A;

[0027] Figure 6 For the present invention Figure 4 A magnified view of point B;

[0028] Figure 7 This is a schematic diagram of the homogenization chamber of the present invention;

[0029] Figure 8 It is a cross-sectional view of the homogenization chamber of the present invention;

[0030] Fig. 9 For the present invention Figure 8 Enlarged view of point C;

[0031] Fig.10 It is a schematic diagram of the guide shell of the present invention.

[0032] In the accompanying drawings, the components represented by the reference numerals are listed as follows:

[0033] 1. Device housing; 2. Feed inlet; 3. Discharge outlet; 4. Homogenization chamber; 5. Filter plate; 6. Centrifugal barrel; 7. Support member; 8. Guide groove; 9. No. 1 gear ring; 10. No. 1 gear; 11. Motor; 12. Fixed plate; 13. Rotating shaft; 14. No. 2 gear; 15. No. 2 gear ring; 16. Adjustment plate; 17. Slide groove; 18. Sliding block; 19. Cross bar; 20. No. 1 spring; 21. No. 1 magnet; 22. No. 2 magnet; 23. Blade; 24. Shaft member; 25. Support block; 26. Column; 27. No. 2 spring; 28. Movable groove; 29. ​​Fixed rod; 30. Protrusion; 31. Guide shell; 32. Guide port; 33. Bending block; 34. Contact column; 35. Bending plate; 36. Top guide surface. DETAILED DESCRIPTION

[0034] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0035] See also Figure 1-Figure 10 The figure shows a herpes zoster virus culture device, including a device shell 1, a feed port 2 is opened on the top of the device shell 1, a discharge port 3 is opened on the bottom of the device shell 1, a homogenization chamber 4 is fixedly installed inside the device shell 1, the upper end of the homogenization chamber 4 is connected to the feed port 2, a rotatable centrifuge barrel 6 is arranged inside the device shell 1, the centrifuge barrel 6 is located below the homogenization chamber 4, the centrifuge barrel 6 rotates with the homogenization chamber 4 as the center through a rotating mechanism, a discharge mechanism is arranged below the homogenization chamber 4, and a crushing mechanism is arranged inside the homogenization chamber 4.

[0036] Specifically, the rotating mechanism includes a support member 7 and a guide groove 8. The support member 7 is fixedly mounted on the outside of the centrifugal barrel 6. The guide groove 8 is provided on the inner wall of the device housing 1. The guide groove 8 and the support member 7 are rotatably connected. A driving assembly is provided below the support member 7.

[0037] Specifically, the driving assembly includes a No. 1 gear ring 9, a No. 1 gear 10 and a motor 11. The motor 11 is fixedly installed below the device housing 1. The output end of the motor 11 passes through the device housing 1 and extends to the inside of the device housing 1. The No. 1 gear 10 is fixedly sleeved on the outside of the output end of the motor 11. The No. 1 gear ring 9 is fixedly installed below the support 7. The No. 1 gear ring 9 and the No. 1 gear 10 are meshed.

[0038] Furthermore, a fixing plate 12 is fixedly installed above the centrifugal barrel 6, and a rotating shaft 13 is fixedly installed above the fixing plate 12. The rotating shaft 13 rotates and penetrates the support member 7. A second gear 14 is fixedly sleeved outside the rotating shaft 13, and a second gear ring 15 is fixedly installed inside the device housing 1. The second gear 14 and the second gear ring 15 are meshed.

[0039] Specifically, the discharge mechanism includes a filter plate 5, which is rotatably installed at the bottom of the homogenization chamber 4. An adjustment plate 16 is arranged between the filter plate 5 and the support member 7. The adjustment plate 16 is connected to the support member 7 through a moving component. A slider 18 is fixedly installed above the adjustment plate 16. A slide groove 17 is provided below the filter plate 5, and the slide groove 17 and the slider 18 are slidably connected.

[0040] Specifically, the moving assembly includes a cross bar 19, which is fixedly installed inside the support member 7, and the cross bar 19 is slidably connected to the adjustment plate 16. The outer movable sleeve of the cross bar 19 is provided with a No. 1 spring 20, and the No. 1 spring 20 is fixedly connected to the adjustment plate 16.

[0041] Furthermore, the moving component also includes a first magnet 21 and a second magnet 22. The first magnet 21 is fixedly mounted on one side of the adjustment plate 16, and the second magnet 22 is fixedly mounted on the inner wall of the device housing 1. The first magnet 21 and the second magnet 22 attract each other.

[0042] Specifically, the crushing mechanism includes a blade 23 and a shaft 24. The shaft 24 is slidably inserted into the interior of the homogenization bin 4 through a lifting assembly. The shaft 24 is horizontally arranged. The number of blades 23 is at least two groups. The blades 23 and the shaft 24 are rotatably connected. The two groups of blades 23 are symmetrically arranged. A movable groove 28 is opened inside the blade 23. A fixed rod 29 slides through the interior of the movable groove 28. The fixed rod 29 is fixedly inserted into the interior of the homogenization bin 4.

[0043] Furthermore, the lifting assembly includes a support block 25, which is fixedly mounted at both ends of the shaft 24, and a column 26 is slidably penetrated inside the support block 25, and the column 26 is fixedly connected to the homogenizing chamber 4, and a second spring 27 is provided on the outer movable sleeve of the column 26, and the second spring 27 is fixedly connected to the support block 25, and a protrusion 30 is fixedly mounted above the filter plate 5, and the protrusion 30 is in contact with the support block 25, and a guide shell 31 is slidably provided on the inner wall of the homogenizing chamber 4. Bending blocks 33 are fixedly connected to the edges of the inner top surface of the guide shell 31, and a guide opening 32 is provided on the inner wall of the homogenization chamber 4 near the upper end of the guide shell 31. The end of the bending block 33 is slidably inserted into the inner side of the guide opening 32. A top guide surface 36 is provided on the upper end surface of the guide shell 31, and two symmetrical bending plates 35 are fixedly connected to the lower side of the guide shell 31. The lower surface of the bending plate 35 is close to the upper side of the blade 23, and a contact column 34 is fixedly connected to the upper end surface of the support block 25.

[0044] When the support block 25 moves upward, the contact column 34 moves upward and touches the bending block 33, causing the guide shell 31 to shake, helping the sample tissue accumulated on the top guide surface 36 to slide down and prevent accumulation. The guide shell 31 rotates synchronously with the homogenization chamber 4. Since the two sides of the guide shell 31 are inclined surfaces, it has the function of guiding the tissue to move downward, helping the sample tissue to reach the lower end of the blade 23 for shredding. The bending plate 35 plays a blocking role, preventing the sample tissue from accumulating on the upper surface of the blade 23, and can guide the sample tissue to slide down to the lower end of the blade 23, so as to better assist the shredding process.

[0045] Working principle: put the sample into the device housing 1 from the feed port 2. In the initial state, the adjustment plate 16 blocks the bottom of the homogenization chamber 4, and the sample falls into the homogenization chamber 4. When the rotating mechanism drives the support 7 to rotate, it can drive the adjustment plate 16 to rotate. Since the adjustment plate 16 is connected to the filter plate 5 through the slide groove 17 and the slider 18, the adjustment plate 16 can mobilize the filter plate 5 to rotate synchronously.

[0046] During this process, the filter plate 5 drives the protrusion 30 to move. During the movement, the protrusion 30 contacts the support block 25 and pushes the support block 25 to move upward. At this time, under the action of the column 26, the No. 2 spring 27 is compressed, and the support block 25 drives the blade 23 to move synchronously through the shaft 24. Since the fixed rod 29 slides inside the movable groove 28, when the blade 23 moves upward, the fixed rod 29 can drive the lower ends of the two adjacent groups of blades 23 to approach each other, so as to shear and crush the sample. When the protrusion 30 is not in contact with the support block 25, the No. 2 spring 27 drives the blade 23 to move downward through the shaft 24. At this time, the lower ends of the two adjacent groups of blades 23 are far away from each other.

[0047] Furthermore, when the filter plate 5 rotates, it can drive the sample above the filter plate 5 to rotate, so that the sample above the filter plate 5 can fully contact the blade 23, which is beneficial to evenly crush the sample inside the homogenization chamber 4 and improve the efficiency of homogenization.

[0048] When the adjusting plate 16 rotates, it can drive the No. 1 magnet 21 to move synchronously. When the No. 1 magnet 21 rotates to be close to the No. 2 magnet 22, since the No. 1 magnet 21 and the No. 2 magnet 22 are attracted to each other, the No. 1 magnet 21 can drive the adjusting plate 16 to move along the length direction of the cross bar 19 above the support 7. At this time, the No. 1 spring 20 is compressed, and the adjusting plate 16 drives the slider 18 to slide inside the slide groove 17. The adjusting plate 16 is moved away from the bottom of the homogenization chamber 4. The processed samples inside the homogenization chamber 4 can pass through the filter plate 5 and fall into the inside of the centrifuge barrel 6. The larger sample tissues remain in the homogenization chamber 4 for secondary processing, so that the intermittent unloading of the homogenized samples can be realized, and there is no need to manually homogenize the samples, which is beneficial to reduce the workload of the staff.

[0049] Furthermore, the rotating mechanism drives the centrifugal bucket 6 to rotate, so that the sample inside the centrifugal bucket 6 can be centrifugally processed, and the processed sample is discharged from the inside of the device housing 1 through the discharge port 3.

[0050] Specifically, the motor 11 is connected to an external power source, and the motor 11 drives the No. 1 gear 10 to rotate. Since the No. 1 gear 10 is meshed with the No. 1 gear ring 9, the motor 11 can drive the support member 7 to rotate inside the guide groove 8 through the No. 1 gear ring 9, thereby driving the centrifugal barrel 6 to rotate with the homogenization chamber 4 as the center.

[0051] Under the action of the fixed plate 12, the centrifugal bucket 6 can drive the second gear 14 to rotate through the rotating shaft 13. Since the second gear 14 is meshed with the second gear ring 15, the second gear 14 drives the centrifugal bucket 6 to rotate through the rotating shaft 13, so that the centrifugal bucket 6 can also add samples to the inside of the centrifugal bucket 6 during centrifugation, which is beneficial to improving the efficiency of centrifugation.

[0052] Refer to the instruction manual Figure 1-Figure 8 , a herpes zoster virus culture process, comprising the following steps:

[0053] Step 1: Add the sample into the homogenization chamber 4, break the sample into small pieces by the breaking mechanism and homogenize;

[0054] Step 2: During step 1, the rotating mechanism drives the centrifugal bucket 6 to rotate with the homogenizing chamber 4 as the center, so that the homogenized sample can pass through the filter plate 5 and fall into the inside of the centrifugal bucket 6;

[0055] Step 3: The centrifuge barrel 6 can rotate on its own while rotating with the homogenization chamber 4 as the center, and the sample inside the centrifuge barrel 6 is centrifugally processed. The processed sample is discharged from the inside of the device housing 1 through the discharge port 3.

[0056] It should be noted that, in this article, relational terms such as first and second, etc. are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any such actual relationship or order between these entities or operations. Moreover, the terms "include", "comprise" or any other variants thereof are intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements includes not only those elements, but also other elements not explicitly listed, or also includes elements inherent to such process, method, article or device.

[0057] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. A herpes zoster virus culture device, comprising a device housing (1), characterized in that: A feed inlet (2) is provided above the device housing (1), a discharge outlet (3) is provided below the device housing (1), a homogenizing chamber (4) is fixedly installed inside the device housing (1), the upper end of the homogenizing chamber (4) is connected to the feed inlet (2), a rotatable centrifuge barrel (6) is provided inside the device housing (1), the centrifuge barrel (6) is located below the homogenizing chamber (4), the centrifuge barrel (6) is rotated with the homogenizing chamber (4) as the center through a rotating mechanism, a discharge mechanism is provided below the homogenizing chamber (4), and a crushing mechanism is provided inside the homogenizing chamber (4).

2. A herpes zoster virus culture device according to claim 1, characterized in that: The rotating mechanism comprises a support member (7) and a guide groove (8); the support member (7) is fixedly mounted on the outside of the centrifugal barrel (6); the guide groove (8) is formed on the inner wall of the device housing (1); the guide groove (8) and the support member (7) are rotatably connected; and a driving assembly is provided below the support member (7).

3. A herpes zoster virus culture device according to claim 2, characterized in that: The driving assembly comprises a first gear ring (9), a first gear (10) and a motor (11); the motor (11) is fixedly mounted below the device housing (1); an output end of the motor (11) penetrates the device housing (1) and extends into the interior of the device housing (1); the first gear (10) is fixedly sleeved outside the output end of the motor (11); the first gear ring (9) is fixedly mounted below the support member (7); and the first gear ring (9) and the first gear (10) are meshed.

4. A herpes zoster virus culture device according to claim 2, characterized in that: A fixing plate (12) is fixedly mounted above the centrifugal bucket (6), a rotating shaft (13) is fixedly mounted above the fixing plate (12), the rotating shaft (13) rotatably penetrates the support member (7), a second gear (14) is fixedly mounted on the outer sleeve of the rotating shaft (13), a second gear ring (15) is fixedly mounted inside the device housing (1), and the second gear (14) is meshed with the second gear ring (15).

5. A herpes zoster virus culture device according to claim 4, characterized in that: The discharge mechanism comprises a filter plate (5), the filter plate (5) being rotatably mounted at the bottom of the homogenization bin (4), an adjustment plate (16) being arranged between the filter plate (5) and the support member (7), the adjustment plate (16) being connected to the support member (7) via a moving assembly, a slider (18) being fixedly mounted above the adjustment plate (16), a slide groove (17) being provided below the filter plate (5), the slide groove (17) being slidably connected to the slider (18).

6. A herpes zoster virus culture device according to claim 5, characterized in that: The moving assembly comprises a cross bar (19), the cross bar (19) being fixedly mounted inside the support member (7), the cross bar (19) being slidably connected to the adjustment plate (16), the outer movable sleeve of the cross bar (19) being provided with a No. 1 spring (20), and the No. 1 spring (20) being fixedly connected to the adjustment plate (16).

7. A herpes zoster virus culture device according to claim 6, characterized in that: The moving assembly further comprises a first magnet (21) and a second magnet (22), wherein the first magnet (21) is fixedly mounted on one side of the adjustment plate (16), and the second magnet (22) is fixedly mounted on the inner wall of the device housing (1), and the first magnet (21) and the second magnet (22) attract each other.

8. The herpes zoster virus culture device according to claim 5, characterized in that: The crushing mechanism comprises a blade (23) and a shaft (24); the shaft (24) is slidably inserted into the interior of the homogenizing chamber (4) via a lifting assembly; the shaft (24) is arranged horizontally; the number of the blades (23) is at least two groups; the blades (23) and the shaft (24) are rotatably connected; the two groups of blades (23) are symmetrically arranged; a movable groove (28) is provided inside the blade (23); a fixed rod (29) is slidably penetrated inside the movable groove (28); and the fixed rod (29) is fixedly inserted into the interior of the homogenizing chamber (4).

9. A herpes zoster virus culture device according to claim 8, characterized in that: The lifting assembly comprises a support block (25), wherein the support block (25) is fixedly mounted at both ends of the shaft (24), a column (26) is slidably penetrated inside the support block (25), the column (26) is fixedly connected to the homogenizing chamber (4), a second spring (27) is provided on the outer movable sleeve of the column (26), the second spring (27) is fixedly connected to the support block (25), a protrusion (30) is fixedly mounted above the filter plate (5), the protrusion (30) is in contact with the support block (25), and a guide shell (31) is slidably provided on the inner wall of the homogenizing chamber (4) ), bending blocks (33) are fixedly connected at the edges of the inner top surface of the guide shell (31), a guide opening (32) is provided on the inner wall of the homogenizing chamber (4) near the upper end of the guide shell (31), the end of the bending block (33) is slidably inserted into the inner side of the guide opening (32), a top guide surface (36) is provided on the upper end surface of the guide shell (31), two symmetrical bending plates (35) are fixedly connected to the lower side of the guide shell (31), the lower surface of the bending plate (35) is close to the upper side of the blade (23), and a contact column (34) is fixedly connected to the upper end surface of the support block (25).

10. A herpes zoster virus culture process, using the device according to any one of claims 1 to 9, characterized in that: The following steps are involved: Step 1: adding a sample into the homogenization chamber (4), breaking the sample into small pieces by a breaking mechanism and homogenizing; Step 2: During step 1, the rotating mechanism drives the centrifugal bucket (6) to rotate with the homogenization chamber (4) as the center, so that the homogenized sample can pass through the filter plate (5) and fall into the interior of the centrifugal bucket (6); Step 3: The centrifuge barrel (6) can rotate on its own while rotating with the homogenizing chamber (4) as the center, so as to centrifuge the sample inside the centrifuge barrel (6), and the processed sample is discharged from the inside of the device housing (1) through the discharge port (3).

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