A kind of experimental mouse anti-fatigue experiment load device

Abstract

The application provides a weight loading device for anti-fatigue experiments on experimental mice, which comprises a mounting structure and a plurality of counterweights. The mounting structure can be wrapped around the tail of an experimental mouse, and a plurality of mounting slots are arranged on the mounting structure. The counterweights are detachably mounted in the corresponding mounting slots. One counterweight can be mounted in each mounting slot. The weight of each counterweight is constant. The mounting structure is wrapped around the tail of an experimental mouse, and the weight of the experimental mouse is changed by placing different numbers of counterweights in different mounting slots of the mounting structure, so that the operation is convenient and the weight is easy to control.

Description

Technical Field

[0001] This invention relates to the field of experimental apparatus technology, specifically to a load-bearing device for an anti-fatigue experiment on laboratory mice. Background Technology

[0002] The efficacy evaluation of anti-fatigue drugs or foods requires anti-fatigue experiments, among which the weighted swimming test of experimental mice is widely used.

[0003] In the weighted swimming experiment for laboratory mice, a certain proportion of the mouse's body weight in lead sheets or blocks needs to be placed on the tail of the mouse before it is placed in water for swimming tests. In practice, it has been found that cutting out a fixed weight of lead sheets or blocks is time-consuming, typically requiring multiple cuts and weighings to obtain the target weight. Furthermore, fixing the loose lead sheets or blocks to the mouse's tail is inconvenient; lead sheets can be clamped to the tail, while lead blocks require string to secure them. Moreover, as the test progresses over several days, the mouse's weight changes, requiring adjustments to the weight of the lead blocks or sheets on the tail to ensure accurate results, further exacerbating these inconveniences. Summary of the Invention

[0004] In view of the shortcomings of the prior art, the present invention provides a load-bearing device for anti-fatigue experiments on laboratory mice, which can solve or at least alleviate one or more of the above-mentioned problems and other problems existing in the prior art.

[0005] This invention provides a weight-bearing device for fatigue resistance experiments on laboratory mice, comprising: An installation structure, which can be covered over the tail of a laboratory mouse and has multiple installation slots thereon; and Multiple counterweights are provided, and the counterweights are detachably installed in the corresponding mounting slots.

[0006] Preferably, the mounting structure is a flexible fixed sleeve; at least one end of the fixed sleeve is open; the mounting groove is formed on the fixed sleeve; and the counterweight can be snapped into the corresponding mounting groove.

[0007] Preferably, it further includes a tightening mechanism; the mounting structure includes: A connecting ring can be fitted over the tail of a laboratory mouse; and Two strip mounting strips, one end of which is connected to the connecting ring, and the two strip mounting strips are arranged symmetrically with respect to the center line of the connecting ring; The mounting grooves are formed on the strip mounting strips and distributed along their length; the tightening mechanism is used to drive the two strip mounting strips to adhere to the tail of the experimental mouse from both sides.

[0008] Preferably, the strip mounting strip includes a magnetic strip mounting portion; one end of the strip mounting portion is connected to the connecting ring; the mounting groove is formed on the strip mounting portion; a plurality of the mounting grooves are distributed along the length direction of the strip mounting portion; the counterweight can be magnetically attracted by the mounting groove.

[0009] Preferably, there are two or more tightening mechanisms; The tightening mechanism includes: Two arc-shaped tightening plates are respectively located outside the two strip-shaped mounting portions; and Two tightening straps, each with its two ends connected to the two ends of the corresponding arc-shaped tightening plate; The distance between the two arc-shaped tightening plates is adjustable; a tightening channel is formed between the tightening band and the corresponding arc-shaped tightening plate; the strip-shaped mounting part passes through the tightening channel.

[0010] Preferably, the arc-shaped tightening plate has one or more limiting holes; the limiting holes allow the counterweight to pass through.

[0011] Preferably, the tightening mechanism further includes four limiting blocks; every two limiting blocks are located in the tightening channel and are connected to the inner wall of the arc-shaped tightening plate; a limiting groove is formed between two adjacent limiting blocks; the strip-shaped mounting part slides in cooperation with the corresponding limiting groove; the tightening band is used to restrict the strip-shaped mounting part to prevent the strip-shaped mounting part from separating from the limiting groove.

[0012] Preferably, the strip mounting strip further includes: A strip-shaped bonding portion, which is connected to the strip-shaped mounting portion, extends along the length direction of the strip-shaped mounting portion; One side of the strip-shaped adhesive portion abuts against the two limiting blocks, and the side of the strip-shaped adhesive portion facing away from the limiting blocks abuts against the tightening band.

[0013] Preferably, the side of the strip-shaped fitting portion facing away from the limiting block is an arc surface; The tightening band includes: An arc-shaped limiting part, wherein the side of the arc-shaped limiting part facing the limiting block is an arc surface, and the side of the arc-shaped limiting part facing the limiting block slides in engagement with the side of the strip-shaped fitting part opposite to the limiting block; and Two elastic connecting parts are respectively connected to both ends of the arc-shaped limiting part, and the end of the elastic connecting part away from the arc-shaped limiting part is connected to the end of the arc-shaped tightening plate.

[0014] Preferably, the tightening mechanism further includes two tightening components; the two tightening components are located on both sides of the arc-shaped tightening plate; The tightening component includes: The first tightening cylinder has one end connected to the end of the arc-shaped tightening plate, and the other end is internally connected to a coaxial first limiting ring. The second tightening cylinder is arranged parallel to the first tightening cylinder, and one end of it is connected to the other tightening plate, and a coaxial second limiting ring is connected inside that end; A first sliding ring is slidably sleeved outside the first tightening cylinder and connected to the second tightening cylinder; and The second sliding ring is slidably sleeved outside the second tightening cylinder and connected to the first tightening cylinder; When the first tightening cylinder and the second tightening cylinder move away from each other, the first sliding ring and the second sliding ring can abut against each other; docking windows are respectively opened on the side of the first tightening cylinder and the second tightening cylinder that are close to each other; the counterweight can be slidably placed into the end of the first tightening cylinder away from the first limiting ring; the counterweight can be slidably placed into the end of the second tightening cylinder away from the second limiting ring; the counterweight in the first tightening cylinder and the counterweight in the second tightening cylinder can be magnetically attracted to each other; the counterweight can abut against the first limiting ring and the second limiting ring.

[0015] Compared with the prior art, the present invention has the following beneficial effects: In this invention, the load on the experimental mouse is changed by placing different numbers of counterweights into different mounting slots on the mounting structure. The operation is convenient and the load is easy to control. Attached Figure Description

[0016] To more clearly illustrate the specific embodiments of the present invention or the technical solutions in the prior art, the accompanying drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. In all the drawings, similar elements or parts are generally identified by similar reference numerals. In the drawings, the elements or parts are not necessarily drawn to scale.

[0017] Figure 1 This is a perspective view of a load-bearing device for an anti-fatigue experiment on laboratory mice according to one embodiment of the present invention; Figure 2 for Figure 1 Another 3D image; Figure 3 for Figure 2 Another 3D view (without connecting rings); Figure 4 for Figure 1 A three-dimensional view of the tightening mechanism; Figure 5 for Figure 4 Another 3D image.

[0018] Figure label: 10. Mounting structure; 11. Mounting groove; 12. Connecting ring; 13. Strip mounting strip; 131. Strip mounting part; 132. Strip fitting part; 20. Counterweight; 30. Tightening mechanism; 31. Arc-shaped tightening plate; 32. Tightening belt; 321. Arc-shaped limiting part; 322. Elastic connecting part; 33. Tightening channel; 34. Limiting hole; 35. Limiting block; 36. Limiting groove; 37. Tightening assembly; 371. First tightening cylinder; 372. First limiting ring; 373. Second tightening cylinder; 374. Second limiting ring; 375. First sliding ring; 376. Second sliding ring; 377. Docking window. Detailed Implementation

[0019] The embodiments of the technical solution of the present invention will now be described in detail with reference to the accompanying drawings. These embodiments are merely illustrative of the technical solution of the present invention and are therefore intended to limit the scope of protection of the present invention.

[0020] It should be noted that, unless otherwise stated, the technical or scientific terms used in this application should have the ordinary meaning as understood by one of ordinary skill in the art to which this invention pertains.

[0021] In the description of this application, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "upper", "lower", "front", "rear", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", "clockwise", "counterclockwise", "axial", "radial", "circumferential", etc., indicating the orientation or positional relationship are based on the orientation or positional relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and are not intended to indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention.

[0022] Furthermore, the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of technical features indicated. In the description of this invention, "a plurality of" means two or more, unless otherwise explicitly defined.

[0023] In this application, unless otherwise expressly specified and limited, the terms "installation," "connection," "linking," and "fixing," etc., should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral part; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication of two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this invention according to the specific circumstances.

[0024] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can mean that the first feature is in direct contact with the second feature, or that the first feature is in indirect contact with the second feature through an intermediate medium. Furthermore, "above," "on top of," and "over" the second feature can mean that the first feature is directly above or diagonally above the second feature, or simply that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature can mean that the first feature is directly below or diagonally below the second feature, or simply that the first feature is at a lower horizontal level than the second feature.

[0025] See Figures 1 to 5 This embodiment provides a load-bearing device for anti-fatigue experiments on laboratory mice, including an installation structure 10 and multiple counterweights 20.

[0026] The mounting structure 10 can be fitted over the tail of a laboratory mouse, and the mounting structure 10 has multiple mounting slots 11. A counterweight 20 is detachably mounted in the corresponding mounting slot 11. One counterweight 20 can be mounted in each mounting slot 11. The weight of a single counterweight 20 is constant.

[0027] During the swimming experiment of laboratory mice, the lead weights and lead sheets were placed on the tail of the mice. However, it was difficult to fix the lead weights and lead sheets in place, and it was also difficult to control the weight of the lead weights and lead sheets when cutting them.

[0028] In this embodiment, the load on the experimental mouse is changed by covering the tail of the experimental mouse with the mounting structure 10 and placing different numbers of counterweights 20 into different mounting slots 11 on the mounting structure 10. The operation is convenient and the load is easy to control.

[0029] In one embodiment, the mounting structure 10 is a flexible fixing sleeve. At least one end of the fixing sleeve is open. A mounting groove 11 is formed on the fixing sleeve. A counterweight 20 can be snapped into the corresponding mounting groove 11. Specifically, the fixing sleeve can be made of silicone or rubber, etc., and the mounting groove 11 is slightly smaller than the counterweight 20, so that the counterweight 20 can be snapped in place after being inserted into the mounting groove 11. Furthermore, the interior of the mounting groove 11 can be curved, and correspondingly, the counterweight 20 can be spherical. Additionally, the fixing sleeve can be relatively thin overall, with only a portion protruding outwards at the mounting groove 11, thereby facilitating control of the overall weight.

[0030] In this embodiment, by fitting the fixing sleeve from its open end onto the tail of the experimental mouse, and using its elasticity to cover and fix the tail of the experimental mouse, a sufficient number of counterweights 20 are installed into the corresponding mounting slots 11 as needed.

[0031] In one embodiment, the load-bearing device for fatigue resistance experiments on laboratory mice further includes a tightening mechanism 30.

[0032] The mounting structure 10 includes a connecting ring 12 and two strip mounting straps 13.

[0033] The connecting ring 12 can be fitted onto the tail of the laboratory mouse. One end of each of the two strip mounting straps 13 is connected to the connecting ring 12, and the two strip mounting straps 13 are symmetrically arranged relative to the center line of the connecting ring 12. Mounting grooves 11 are formed on the strip mounting straps 13 and distributed along their length. The tightening mechanism 30 is used to drive the two strip mounting straps 13 to adhere to the tail of the laboratory mouse from both sides. The connecting ring 12 may be elastic so that it can be fixed to the tail of the laboratory mouse; in addition, a clamping band may be provided on the outside of the connecting ring 12 to clamp the connecting ring 12 to the tail of the laboratory mouse.

[0034] In practice, it has been found that when the tail of a laboratory mouse is inserted into a relatively soft and flexible fixation tube, the fixation tube must fit snugly against the tail to better cover it and prevent it from falling off. This results in a small inner diameter of the fixation tube itself, making it difficult for the tail of the laboratory mouse to pass through the entire fixation tube easily.

[0035] In this embodiment, the mouse's tail only needs to pass through the connecting ring 12 and be positioned between the two strip mounting straps 13. The distance between the two strip mounting straps 13 is relatively wide, and since there are only two strip mounting straps 13, there is no difficulty in passing the mouse's tail between them. Then, the tightening structure brings the two strip mounting straps 13 closer together, abutting against the mouse's tail from both sides, thus fixing the two strip mounting straps 13 to the mouse's tail. Furthermore, since there are only two strip mounting straps 13, the operation is convenient, time-saving, and labor-saving.

[0036] In addition, by attaching the two strip mounting straps 13 to both sides of the tail of the experimental mouse through the tightening mechanism 30, the resistance caused by the scattered strip mounting straps 13 when the experimental mouse swims can be avoided, which would lead to inaccurate experimental results.

[0037] In one embodiment, the strip mounting strip 13 includes a magnetic strip mounting portion 131. One end of the strip mounting portion 131 is connected to a connecting ring 12. Mounting grooves 11 are formed on the strip mounting portion 131. A plurality of mounting grooves 11 are distributed along the length direction of the strip mounting portion 131. The counterweight 20 can be magnetically attracted by the mounting grooves 11. The strip mounting portion 131 may be made of magnetic rubber. The inner surface of the mounting groove 11 may be spherical, and the counterweight 20 may be spherical or a magnetic bead.

[0038] In this embodiment, the magnetic attraction between the strip mounting part 131 and the counterweight 20 makes it more convenient to control the load on the experimental mice.

[0039] In one embodiment, there are two or more tightening mechanisms 30 (only one is shown in the figure), and the tightening mechanism 30 includes two arc-shaped tightening plates 31 and two tightening straps 32.

[0040] Two curved tightening plates 31 are located outside the two strip-shaped mounting portions 131. The two ends of each tightening strap 32 are connected to the two ends of the corresponding curved tightening plate 31. The distance between the two curved tightening plates 31 is adjustable. A tightening channel 33 is formed between the tightening strap 32 and the corresponding curved tightening plate 31, through which the strip-shaped mounting portion 131 passes. The two tightening straps 32 are positioned between the two curved tightening plates 31. The inner surface of the curved tightening plate 31 is curved and can conform to the outer curved surface of the strip-shaped mounting portion 131.

[0041] In this embodiment, when the mouse tail is not placed between the two strip mounting parts 131, a certain distance is maintained between the two strip mounting parts 131 under the adjustment of the two arc-shaped tightening plates 31, thus facilitating the subsequent passage of the mouse tail between the two strip mounting parts 131. After the distance between the two arc-shaped tightening plates 31 is reduced, the two strip mounting parts 131 are fitted and fixed to the mouse tail. Since there are two or more tightening mechanisms 30, the strip mounting parts 131 are fixed to the mouse tail at multiple points, thereby reducing the probability of the device detaching from the mouse. Furthermore, the arc-shaped tightening plates 31 can move along the length of the strip mounting parts 131, thereby adjusting the fixed position of the device in the laboratory.

[0042] In one embodiment, the two arc-shaped tightening plates 31 are moved to a suitable position along the tail of the laboratory mouse and brought close together to fix the device to the tail of the laboratory mouse. Simultaneously, the mounting block is passed through the limiting hole 34 on the arc-shaped tightening plate 31 and magnetically fixed to the corresponding mounting groove 11. The counterweight 20 can limit the arc-shaped tightening plate 31 to prevent it from moving along the length of the mouse's tail while the laboratory mouse is swimming, thus preventing the device from detaching from the tail. That is, the counterweight 20 can be used both for weight distribution and for limiting the arc-shaped tightening plate 31. Furthermore, the magnetic attraction of the counterweight 20 into the mounting grooves 11 on both sides of the arc-shaped tightening plate 31 can abut against the arc-shaped tightening plate, thereby further limiting the arc-shaped tightening plate 31.

[0043] In one embodiment, the tightening mechanism 30 further includes four limiting blocks 35; every two limiting blocks 35 are located in the tightening channel 33 and are connected to the inner wall of the arc-shaped tightening plate 31; a limiting groove 36 is formed between two adjacent limiting blocks 35; the strip mounting portion 131 slides in cooperation with the corresponding limiting groove 36; the tightening band 32 is used to restrict the strip mounting portion 131 to prevent the strip mounting portion 131 from separating from the limiting groove 36.

[0044] In this embodiment, the strip mounting part 131 gradually shrinks from one end of the connecting ring 12 to the other end in order to maintain a fit with the tail of the experimental mouse. Therefore, the size of the tightening channel 33 is slightly larger than that of the strip mounting part 131. In order to prevent the strip mounting part 131 from sliding laterally in the tightening channel 33, a limiting groove 36 is provided, so that the device can be stably fixed to the tail of the experimental mouse.

[0045] In one embodiment, the strip mounting strip 13 further includes a strip fitting portion 132.

[0046] The strip-shaped bonding portion 132 is connected to the strip-shaped mounting portion 131, and the strip-shaped bonding portion 132 extends along the length direction of the strip-shaped mounting portion 131. One side of the strip-shaped bonding portion 132 abuts against the two limiting blocks 35, and the side of the strip-shaped bonding portion 132 facing away from the limiting blocks 35 abuts against the tightening band 32.

[0047] In this embodiment, the strip-shaped fitting portion 132 increases the contact area with the tail of the experimental mouse, thereby making the fixation of the device to the tail of the experimental mouse more secure. In addition, the strip-shaped fitting portion 132 ensures that the strip-shaped mounting portion 131 is always located in the limiting groove 36, so that the positions of the two strip-shaped mounting portions 131 and the two strip-shaped fitting portions 132 are controllable under the control of the arc-shaped tightening plate 31, which facilitates the subsequent passage of the experimental mouse tail.

[0048] In one embodiment, the side of the strip-shaped fitting portion 132 facing away from the limiting block 35 is an arc surface.

[0049] The tightening band 32 includes an arc-shaped limiting part 321 and two elastic connecting parts 322.

[0050] The side of the arc-shaped limiting part 321 facing the limiting block 35 is arc-shaped, and the side of the arc-shaped limiting part 321 facing the limiting block 35 slides in engagement with the side of the strip-shaped fitting part 132 facing away from the limiting block 35. Two elastic connecting parts 322 are respectively connected to both ends of the arc-shaped limiting part 321, and the end of the elastic connecting part 322 away from the arc-shaped limiting part 321 is connected to the end of the arc-shaped tightening plate 31. Specifically, the arc-shaped limiting part 321 can maintain its arc-shaped structure. The tightening band 32 is roughly "W"-shaped.

[0051] In this embodiment, under the pull of the two elastic connecting parts 322, the arc-shaped limiting part 321 applies external force to the strip-shaped fitting part 132, thereby ensuring that the strip-shaped mounting part 131 is located in the mounting groove 11. The angle formed at the connection between the two elastic connecting parts 322 and the arc-shaped limiting part 321 faces the arc-shaped tightening plate 31, and both angles are less than 180 degrees. This limits the sides of the strip-shaped fitting part 132 when they abut against the elastic connecting parts 322, preventing the strip-shaped fitting part 132 from moving laterally. Furthermore, the inner side of the arc-shaped limiting part 321 is also arc-shaped, allowing it to fit more closely to the tail of the experimental mouse, facilitating fixation.

[0052] In one embodiment, the tightening mechanism 30 further includes two tightening components 37; the two tightening components 37 are located on both sides of the arc-shaped tightening plate 31; The tightening assembly 37 includes a first tightening cylinder 371, a second tightening cylinder 373, a first sliding ring 375, and a second sliding ring 376.

[0053] One end of the first tightening cylinder 371 is connected to the end of the arc-shaped tightening plate 31, and the other end is internally connected to a coaxial first limiting ring 372. The second tightening cylinder 373 is arranged parallel to the first tightening cylinder 371. One end of the second tightening cylinder 373 is connected to another arc-shaped tightening plate 31, and this end is internally connected to a coaxial second limiting ring 374. A first sliding ring 375 is slidably sleeved outside the first tightening cylinder 371 and is connected to the second tightening cylinder 373. A second sliding ring 376 is slidably sleeved outside the second tightening cylinder 373 and is connected to the first tightening cylinder 371.

[0054] When the first tightening cylinder 371 and the second tightening cylinder 373 move away from each other, the first sliding ring 375 and the second sliding ring 376 can abut against each other. A mating window 377 is provided on the side of the first tightening cylinder 371 and the second tightening cylinder 373 that are close to each other. A counterweight 20 can be slidably inserted into the end of the first tightening cylinder 371 away from the first limiting ring 372. A counterweight 20 can be slidably inserted into the end of the second tightening cylinder 373 away from the second limiting ring 374. The counterweight 20 in the first tightening cylinder 371 and the counterweight 20 in the second tightening cylinder 373 can be magnetically attracted to each other. The counterweight 20 can abut against the first limiting ring 372 and the second limiting ring 374. Specifically, the counterweight 20 is magnetic, and the first tightening cylinder 371 and the second tightening cylinder 373 can have a hollow structure, allowing the counterweight 20 to slide axially within the first tightening cylinder 371 and the second tightening cylinder 373. The counterweights 20 inside the first tightening cylinder 371 and the second tightening cylinder 373 are spherical and can pass through the docking window 377 to abut against each other to enhance their magnetic attraction. Furthermore, a removal window is provided on the opposite side of the first tightening cylinder 371 and the second tightening cylinder 373. Part of the counterweight 20 protrudes outward from the removal window, allowing it to be pushed and easily removed from the first tightening cylinder 371 and the second tightening cylinder 373. Because the counterweights 20 in the first tightening cylinder 371 and the second tightening cylinder 373 are docked within the docking window 377, the counterweight 20 in the second tightening cylinder 373 is less likely to detach from the second tightening cylinder 373, thus keeping the first tightening cylinder 371 and the second tightening cylinder 373 relatively stationary.

[0055] In this embodiment, as Figure 5 The counterweight 20 is inserted from the same side end (upper end in the figure) of the first tightening cylinder 371 and the second tightening cylinder 373. When placing the counterweight 20, one counterweight 20 is first placed into the first tightening cylinder 371, and then the other counterweight 20 is placed into the second tightening cylinder 373. Under the action of gravity, the two counterweights 20 stop at the bottom of the first tightening cylinder 371 and the second tightening cylinder 373 and are magnetically attracted to each other. The counterweights 20 can then be placed into the first tightening cylinder 371 and the second tightening cylinder 373 in this order. Under the constraint of the first sliding ring 375 and the second sliding ring 376, the first tightening cylinder 371 and the second tightening cylinder 373 can slide closer or further apart, thereby allowing the arc-shaped tightening plates 31 on both sides to move closer or further apart. Furthermore, the first sliding ring 375 and the second sliding ring 376 also prevent the first tightening cylinder 371 and the second tightening cylinder 373 from detaching from each other. Multiple counterweights 20 inside the first tightening cylinder 371 and the second tightening cylinder 373 are magnetically attracted to each other, which allows the arc-shaped tightening plates 31 on both sides to maintain a constant distance, thereby fixing the device to the tail of the experimental mouse.

[0056] Numerous specific details are set forth in this specification. However, it will be understood that embodiments of the invention may be practiced without these specific details. In some instances, well-known methods, structures, and techniques have not been shown in detail so as not to obscure the understanding of this specification.

[0057] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention, and not to limit them. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some or all of the technical features therein. Such modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of the present invention, and they should all be covered within the scope of the claims and specification of the present invention.

Claims

1. A load-bearing device for fatigue resistance experiments on laboratory mice, characterized in that, include: Mounting structure (10), which can cover the tail of a laboratory mouse and has multiple mounting slots (11) thereon; and Multiple counterweights (20) are detachably installed in the corresponding mounting slots (11); The load-bearing device for the experimental mouse fatigue resistance experiment also includes a tightening mechanism (30); the mounting structure (10) includes: Connecting ring (12) can be fitted onto the outside of the tail of the laboratory mouse; and Two strip mounting strips (13) are provided, one end of which is connected to the connecting ring (12). The two strip mounting strips (13) are arranged symmetrically with respect to the center line of the connecting ring (12). The mounting groove (11) is formed on the strip mounting strip (13) and distributed along its length; the tightening mechanism (30) is used to drive the two strip mounting strips (13) to adhere to the tail of the experimental mouse from both sides; The strip mounting strip (13) includes a magnetic strip mounting portion (131); one end of the strip mounting portion (131) is connected to the connecting ring (12); the mounting groove (11) is formed on the strip mounting portion (131); a plurality of the mounting grooves (11) are distributed along the length direction of the strip mounting portion (131); the counterweight (20) can be magnetically attracted by the mounting groove (11); The tightening mechanism (30) is provided in two or more parts; The tightening mechanism (30) includes: Two arc-shaped tightening plates (31) are respectively located outside the two strip-shaped mounting portions (131); and Two tightening straps (32), each of which has its two ends connected to the two ends of the corresponding arc-shaped tightening plate (31); The distance between the two arc-shaped tightening plates (31) is adjustable; a tightening channel (33) is formed between the tightening band (32) and the corresponding arc-shaped tightening plate (31); the strip mounting part (131) passes through the tightening channel (33).

2. The anti-fatigue device for experimental mice according to claim 1, wherein, The arc-shaped tightening plate (31) has one or more limiting holes (34); the limiting holes (34) allow the counterweight (20) to pass through.

3. The anti-fatigue device for experimental mice according to claim 2, wherein, The tightening mechanism (30) further includes four limiting blocks (35); each pair of limiting blocks (35) is located in the tightening channel (33) and is connected to the inner wall of the arc-shaped tightening plate (31); a limiting groove (36) is formed between two adjacent limiting blocks (35); the strip mounting part (131) slides with the corresponding limiting groove (36); the tightening band (32) is used to restrict the strip mounting part (131) to prevent the strip mounting part (131) from separating from the limiting groove (36).

4. The anti-fatigue device for experimental mice according to claim 3, wherein, The strip mounting band (13) also includes: A strip-shaped bonding portion (132) is connected to the strip-shaped mounting portion (131), and the strip-shaped bonding portion (132) extends along the length direction of the strip-shaped mounting portion (131); One side of the strip-shaped adhesive portion (132) abuts against the two limiting blocks (35), and the side of the strip-shaped adhesive portion (132) facing away from the limiting blocks (35) abuts against the tightening band (32).

5. The anti-fatigue device for experimental mice according to claim 4, wherein the load is 0.5-2.0 g. The side of the strip-shaped fitting part (132) facing away from the limiting block (35) is an arc surface; The tightening band (32) includes: An arc-shaped limiting part (321) is provided, wherein the side of the arc-shaped limiting part (321) facing the limiting block (35) is an arc surface, and the side of the arc-shaped limiting part (321) facing the limiting block (35) slides in cooperation with the side of the strip-shaped fitting part (132) facing away from the limiting block (35); and Two elastic connecting parts (322) are respectively connected to both ends of the arc-shaped limiting part (321), and one end of the elastic connecting part (322) away from the arc-shaped limiting part (321) is connected to the end of the arc-shaped tightening plate (31).

6. The anti-fatigue device for experimental mice according to claim 5, wherein, The tightening mechanism (30) further includes two tightening components (37); the two tightening components (37) are located on both sides of the arc-shaped tightening plate (31); The tightening assembly (37) includes: The first tightening cylinder (371) has one end connected to the end of the arc-shaped tightening plate (31), and the other end is internally connected to a coaxial first limiting ring (372). The second tightening cylinder (373) is arranged in parallel with the first tightening cylinder (371), and one end of it is connected to the other tightening plate, and a coaxial second limiting ring (374) is connected inside that end. The first sliding ring (375) is slidably sleeved outside the first tightening cylinder (371) and connected to the second tightening cylinder (373); and The second sliding ring (376) is slidably sleeved outside the second tightening cylinder (373) and connected to the first tightening cylinder (371); When the first tightening cylinder (371) and the second tightening cylinder (373) move away from each other, the first sliding ring (375) and the second sliding ring (376) can abut against each other; the first tightening cylinder (371) and the second tightening cylinder (373) are respectively provided with docking windows (377) on the side that are close to each other; the counterweight (20) can be slidably placed in the end of the first tightening cylinder (371) away from the first limiting ring (372); the counterweight (20) can be slidably placed in the end of the second tightening cylinder (373) away from the second limiting ring (374); the counterweight (20) in the first tightening cylinder (371) and the counterweight (20) in the second tightening cylinder (373) can be magnetically attracted to each other; the counterweight (20) can abut against the first limiting ring (372) and the second limiting ring (374).

Images