Dry-type cell resuscitator

Abstract

The invention provides a dry-type cell resuscitator. The dry-type cell resuscitator comprises a base, a tray, a pressing plate assembly, a swinging device and a control device, the tray is installed on the base, the pressing plate assembly covers the tray, and a resuscitation cabin is formed between the pressing plate assembly and the tray; the pressing plate assembly comprises a pressure buffering plate, a pressing plate and a pressure buffering connecting device, one end of the pressing plate is rotationally connected with the base, and the pressure buffering plate is connected with the pressing plate through the pressure buffering connecting device; the slow pressing plate and the bearing surface of the tray are oppositely arranged, heating pieces are arranged on the side, back to the slow pressing plate, of the tray and the side, back to the tray, of the slow pressing plate, and the slow pressing plate and the tray are both made of rigid heat conduction materials; the swing device comprises an eccentric driving assembly and a spring assembly, the eccentric driving assembly and the spring assembly are matched to drive the tray to swing, and the heating piece and the eccentric driving assembly are both electrically connected with the control device. The dry-type cell resuscitator disclosed by the invention can realize automatic control, does not need to be operated by excessive personnel, saves manpower, reduces the probability of misoperation, and is short in cell resuscitation time.

Description

Technical Field

[0001] The invention relates to the technical field of cell resuscitation, in particular to a dry cell resuscitation instrument. Background Art

[0002] With the development of life science and technology, cell therapy technology is changing with each passing day. The preparation process of cell products usually involves cell freezing and thawing. When thawing cells, the best operation is to quickly heat up the cell freezing bag just taken out of the liquid nitrogen storage device, so that the "ice" in the bag melts 80-90%, and quickly passes through -5℃~0℃ where the cells are most vulnerable, to avoid ice crystals recrystallizing and causing damage to the cells, and to avoid the "ice" in the bag completely melting and affecting the cell viability. The existing mainstream water bath resuscitation method, the resuscitation completion time and sample survival rate depend entirely on the operator's experience, the cell resuscitation time is long, it is easy to make mistakes, and the resuscitation process cannot be quantified; water bath resuscitation mostly involves manually shaking the cryopreservation tube, which consumes a lot of manpower. Summary of the invention

[0003] The purpose of the present invention is to provide a dry cell recovery instrument, which has the advantages of being able to realize automatic control, not requiring too many people to operate, saving manpower, reducing the probability of misoperation, and shortening the cell recovery time.

[0004] In order to solve the problems in the prior art, the present invention provides a dry cell resuscitation instrument, which includes: a base, a tray, a pressing plate assembly, a swing device and a control device;

[0005] The tray is mounted on the base, and the pressure plate assembly covers the tray to form a resuscitation chamber between the pressure plate assembly and the tray;

[0006] The pressure plate assembly includes a pressure relief plate, a pressure relief plate and a pressure relief connection device, one end of the pressure relief plate is rotatably connected to the base, and the pressure relief plate is connected to the pressure relief plate through the pressure relief connection device and can move up and down relative to the pressure relief plate;

[0007] The pressure relief plate is arranged opposite to the bearing surface of the tray, and a heating sheet is arranged on the side of the tray facing away from the pressure relief plate and the side of the pressure relief plate facing away from the tray, and the pressure relief plate and the tray are both made of rigid heat-conducting material;

[0008] The swing device includes an eccentric drive assembly and a spring assembly. The eccentric drive assembly cooperates with the spring assembly to drive the tray to swing. The heating plate and the eccentric drive assembly are both electrically connected to the control device.

[0009] Optionally, the eccentric drive assembly comprises: an eccentric wheel, an eccentric pad and a DC motor, wherein the DC motor is mounted on the base, the eccentric wheel is connected to the DC motor, and the eccentric pad is fixed to the lower end surface of the tray and is located above the eccentric wheel;

[0010] The spring assembly includes a first spring sleeve, a spring shaft, a compression spring and a second spring sleeve. The first spring sleeve is fixed on the tray, the second spring sleeve is fixed on the base, and the first spring sleeve and the second spring sleeve are arranged opposite to each other. The compression spring sleeve is arranged on the spring shaft, one end of the spring shaft is a fixed end, and the fixed end is fixedly connected to the first spring sleeve. The other end of the spring shaft is a free end, and the free end is inserted into the second spring sleeve.

[0011] Optionally, the swing device further comprises: a first connecting block and a mounting seat;

[0012] The mounting seat is fixed on the base, one side of the first connecting block has a rotating shaft, the rotating shaft is inserted into a through hole provided in the mounting seat, and the other side of the first connecting block is fixedly connected to the tray.

[0013] Optionally, the swing device further comprises: a second connecting block, a bearing seat, a rotating shaft and a deep groove ball bearing;

[0014] The deep groove ball bearing is installed in the bearing seat, one end of the rotating shaft is inserted into the deep groove ball bearing, and the other end is fixedly connected to the tray through the second connecting block.

[0015] Optionally, the pressure-relieving connection device comprises: a pressure-relieving spring, a T-shaped connector, a pin and a linear bearing;

[0016] The T-shaped connector includes a horizontal part and a vertical part, the linear bearing is installed in a first mounting hole opened in the horizontal part, the pressure relief spring is sleeved on the pin shaft, and the shaft end of the pin shaft passes through the linear bearing and is fixedly connected to the pressure plate;

[0017] The pressure plate is a rectangular frame structure, and a groove is arranged on the inner side of the rectangular frame structure to avoid the vertical part of the T-shaped connector, and the vertical part is fixedly connected to the pressure relief plate.

[0018] Optionally, the base comprises: an upper bottom plate, a lower bottom plate and a hinge base;

[0019] The upper floor plate and the lower floor plate are fixedly connected via columns, and the hinge base is fixed on the upper floor plate;

[0020] A crank is installed at one end of the pressure plate rotatably connected to the base. The crank is hinged to the hinge base through a damping hinge. A crank limit block is provided on the hinge base. The crank limit block is used to limit the rotation angle of the crank.

[0021] Optionally, it also includes: an L-shaped baffle and a flip-cover auxiliary device;

[0022] The L-shaped baffle is mounted on the upper bottom plate and is located below the crank;

[0023] The flip cover auxiliary device comprises: a nitrogen spring push plate, a nitrogen spring, a nitrogen spring push block and a slide rail;

[0024] The slide rail is installed on the upper base plate and is located between two symmetrically arranged hinge bases. One end of the nitrogen spring push plate is installed on the slide rail, and the other end of the nitrogen spring push plate is against the nitrogen spring push block. The nitrogen spring push block is fixed on the crank.

[0025] One end of the nitrogen spring is fixedly connected to the upper bottom plate through a nitrogen spring base, and the other end is fixedly connected to the nitrogen spring push plate.

[0026] Optionally, it also includes: a housing, an electromagnet, a micro switch, a suction piece and a contact switch trigger;

[0027] The housing comprises an upper cover plate and an intermediate cover shell, wherein the upper cover plate is mounted on the pressure plate assembly, and the intermediate cover shell surrounds the base and the tray and is connected to the lower bottom plate of the base;

[0028] The electromagnet and the micro switch are both fixed to the upper edge of the intermediate cover shell, the suction piece and the contact switch trigger are both fixed to the pressure plate, and the suction piece corresponds to the position of the electromagnet, and the contact switch trigger corresponds to the position of the micro switch.

[0029] Optionally, it also includes: a control panel, a barcode scanner, an ultraviolet lamp and a cooling fan;

[0030] The control panel and the barcode scanner are respectively arranged in the windows opened in the intermediate cover shell, the control device and the cooling fan are both installed on the lower bottom plate, and the lower bottom plate is provided with an air inlet hole;

[0031] The ultraviolet lamp is installed on the inner wall of the intermediate cover shell and is located above the tray. The control panel, the barcode scanner, the ultraviolet lamp and the cooling fan are all electrically connected to the control device.

[0032] Optionally, it also includes: a vibration motor, a liquid leakage detector and a temperature detection device;

[0033] The vibration motor is fixed to a side of the tray facing away from the pressure relief plate;

[0034] The tray is provided with a drain port, the liquid leakage detector is generally provided on a drain pipe, and the drain pipe is connected to the drain port;

[0035] The temperature detection device includes a first temperature sensor, a second temperature sensor, and a third temperature sensor, wherein the first temperature sensor is arranged on the carrying surface of the tray, the second temperature sensor is arranged on the side of the pressure relief plate facing away from the tray and the side of the tray facing away from the pressure relief plate, and the third temperature sensor is arranged in the heating plate;

[0036] The vibration motor, the liquid leakage detector, the first temperature sensor, the second temperature sensor and the third temperature sensor are all electrically connected to the control device.

[0037] As described above, the dry cell resuscitation instrument of the present invention has the following beneficial effects: the dry cell resuscitation instrument of the present invention has the advantages of being able to realize automatic control by setting a base, a tray, a pressure plate assembly, a swing device and a control device, not requiring too many people to operate, saving manpower, reducing the probability of misoperation, and shortening the cell resuscitation time. BRIEF DESCRIPTION OF THE DRAWINGS

[0038] Figure 1 It is a three-dimensional structural schematic diagram of the dry cell resuscitation instrument of the present invention.

[0039] Figure 2 It is a three-dimensional structural schematic diagram of the dry cell resuscitation instrument after the cover is opened.

[0040] Figure 3 It is a front-view stereoscopic structural schematic diagram of the internal structure of the dry cell resuscitation instrument of the present invention.

[0041] Figure 4 It is a rear three-dimensional structural schematic diagram of the internal structure of the dry cell resuscitation instrument of the present invention.

[0042] Figure 5 It is a schematic diagram of the three-dimensional structure of the swing device in the dry cell resuscitation instrument of the present invention.

[0043] Figure 6 is a rear view of the dry cell resuscitation instrument of the present invention;

[0044] Figure 7 is a cross-sectional view of the dry cell resuscitation instrument of the present invention;

[0045] Figure 8 is an exploded view of the pressure plate assembly of the present invention;

[0046] Fig. 9 is an exploded view of the spring assembly of the present invention;

[0047] Fig.10 It is a three-dimensional structural schematic diagram of the T-shaped connector of the present invention;

[0048] Fig.11 is a schematic diagram of the three-dimensional structure of a mounting base according to an embodiment of the present invention;

[0049] Fig.12 is a schematic diagram of the three-dimensional structure of a first connecting block according to an embodiment of the present invention;

[0050] Fig.13 is a cross-sectional view of a swing device according to another embodiment of the present invention;

[0051] Fig.14 is a three-dimensional structural schematic diagram of a bearing seat according to another embodiment of the present invention;

[0052] Fig.15 It is a schematic diagram of the three-dimensional structure of a second connecting block according to another embodiment of the present invention.

[0053] Component number description: 1. Upper cover, 2. Control panel, 3. Barcode scanner, 4. Intermediate cover, 5. Pressure relief plate, 6. Tray, 7. UV lamp, 8. First temperature sensor, 9. Electromagnet, 10. Micro switch, 11. Pressure relief spring, 12. T-type connector, 13. Pin, 14. Linear bearing, 15. Connecting assembly, 16. Crank, 17. Damping hinge, 18. Hinge base, 19. L-shaped baffle, 20. Upper bottom plate, 21. First connecting block, 22. Mounting seat, 23. Network cable interface, 24. Lower bottom plate, 25. Second connecting block, 26. Bearing seat, 27. Suction piece, 28. Contact switch trigger, 2 9. USB interface, 30. Pressure plate, 31. Heating plate, 32. Second temperature sensor, 33. First spring sleeve, 34. Crank limit block, 35. Nitrogen spring base, 36. Nitrogen spring push plate, 37. Nitrogen spring, 38. Nitrogen spring push block, 39. Cover plate, 40. DC motor, 41. Motor mounting block, 42. Spring shaft, 43. Compression spring, 44. Second spring sleeve, 45. Slide rail, 46. Deep groove ball bearing, 47. Rotating shaft, 48. Eccentric wheel, 49. Eccentric pad, 50. Cooling fan, 51. Vibration motor, 52. Power socket, 12a. First mounting hole, 12b. Second mounting hole. DETAILED DESCRIPTION

[0054] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0055] The preferred embodiments described below are for example only, and those skilled in the art may think of other obvious variations. The basic principles of the present invention defined in the following description may be applied to other embodiments, variations, improvements, equivalents, and other technical solutions that do not deviate from the spirit and scope of the present invention.

[0056] Those skilled in the art should understand that, in the disclosure of the present invention, the orientation or position relationship indicated by the terms "longitudinal", "lateral", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", etc. are based on the orientation or position relationship shown in the drawings, which are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operate in a specific orientation. Therefore, the above terms should not be understood as limiting the present invention.

[0057] With the development of science and technology, the demand for the cryopreservation and resuscitation of existing cells has become increasingly strong. The mainstream water bath resuscitation method is to revive in constant temperature water at 37°C, which is prone to infection of resuscitated cells; and the completion time of resuscitation and the survival rate of samples depend entirely on the operator's experience. The cell resuscitation time is long, it is easy to make mistakes, and the resuscitation process cannot be quantified; water bath resuscitation is mostly done by manually shaking the cryopreservation tube, which consumes a lot of manpower; and the energy consumed by heating water to 37°C is much greater than the energy consumed by heating metal to the same temperature.

[0058] Embodiment 1

[0059] See also Figures 1 to 6 As shown, the present invention provides a dry cell resuscitation instrument, which includes: a base, a tray 6, a pressure plate assembly, a swing device and a control device;

[0060] The tray 6 is mounted on the base, and the pressing plate assembly covers the tray 6 to form a resuscitation chamber between the pressing plate assembly and the tray 6;

[0061] The pressure plate assembly includes a pressure relief plate 5, a pressure relief plate 30 and a pressure relief connection device, one end of the pressure relief plate 30 is rotatably connected to the base, and the pressure relief plate 5 is connected to the pressure relief plate 30 through the pressure relief connection device and can move up and down relative to the pressure relief plate 30;

[0062] The pressure relief plate 5 is arranged opposite to the bearing surface of the tray 6, and a heating plate 31 is arranged on the side of the tray 6 facing away from the pressure relief plate 5 and the side of the pressure relief plate 5 facing away from the tray 6, and the pressure relief plate 5 and the tray 6 are both made of rigid heat-conducting material;

[0063] The swing device includes an eccentric drive assembly and a spring assembly. The eccentric drive assembly cooperates with the spring assembly to drive the tray 6 to swing. The heating plate 31 and the eccentric drive assembly are both electrically connected to the control device.

[0064] Specifically, the side of the tray 6 facing the pressure relief plate 5 is a bearing surface, and the side of the tray 6 facing away from the pressure relief plate 5 is a bottom surface of the tray 6 , on which a heating plate 31 is disposed.

[0065] There is a preset distance between the pressure relief plate 5 and the pressure plate 30 in the pressure plate assembly, and the pressure relief plate 5 can move up and down relative to the pressure plate 30. When the pressure plate assembly is in a natural state, the distance between the pressure relief plate 5 and the pressure plate 30 is L1, and when the pressure plate assembly is in a compressed state, the distance between the pressure relief plate 5 and the pressure plate 30 is L2. When the tray 6 is closed without a frozen bag, the pressure plate assembly is in a natural state, the pressure relief plate 5 and the pressure plate 30 maintain a maximum distance, and the pressure relief plate 5 is close to the tray 6. After the frozen bag is placed on the tray 6, the lid is closed, the pressure relief plate 5 is subjected to force and moves relative to the pressure plate 30, and the distance between the pressure relief plate 5 and the pressure plate 30 is reduced. The maximum distance that the pressure relief plate 5 moves relative to the pressure plate 30, that is, the size of L1-L2 is set according to the height of the largest size of the frozen bag after it is filled with liquid and frozen. The shape and size of the pressure relief plate 5 are set according to the shape and size of the bearing area of ​​the tray 6.

[0066] In this embodiment, the tray 6 includes a rectangular bottom plate and a rectangular frame, wherein the rectangular frame surrounds the rectangular bottom plate and is integrally connected to the rectangular bottom plate. Figure 3 As shown, the rectangular frame of the tray 6 has a rectangular bearing area, the surface of the bearing area is flat and is surrounded by edges (numbers not shown in the figure), the height of the edges is slightly higher than the surface of the bearing area but lower than the height of the rectangular frame.

[0067] Correspondingly, the pressure relief plate 5 is a rectangular flat plate structure. When the pressure plate assembly is covered on the tray 6, the pressure relief plate 5 is close to the load-bearing area of ​​the tray 6, and the edge of the pressure relief plate 5 contacts the surrounding edge of the load-bearing area. At this time, the distance between the pressure relief plate 5 and the tray 6 is less than the height of the rectangular frame of the tray 6.

[0068] In this embodiment, the heating plate 31 heats the tray 6 by means of electrical heating; the swing device allows the liquid in the cryopreservation bag to move continuously during the cell recovery process, so that the temperature in the cryopreservation bag is relatively uniform.

[0069] Specifically, the heating sheet 31 includes a heating film and an insulating layer covering the heating film. The thickness of the heating film is about 1 mm, and the thickness of the insulating layer is about 10 mm. The heating film can be a Peltier, a graphene electric heating film or other flexible heating film, and the heating sheet 31 can evenly heat the heat-conducting material to a set temperature.

[0070] In this embodiment, the tray 6 and the pressure relief plate 5 are made of metal plates (e.g., aluminum plates) with excellent thermal conductivity. The heating film is attached to the metal plates and can directly and evenly transfer heat to the tray 6 and the pressure relief plate 5, thereby increasing the temperature in the resuscitation chamber.

[0071] In this embodiment, the temperature of the dry cytometer is Figure 4 The heating plate 31 is controlled to a preset temperature. The preset temperature is 30°C-42°C with an error of ±0.5°C, which can meet most cell recovery environments.

[0072] The dry cell resuscitation instrument of the present invention can reduce the cell resuscitation time and realize automatic control by setting the base, the tray 6, the pressure plate, the swing device and the control device, without the need for too many people to operate, saving manpower and reducing the probability of human error operation; the data records are complete, and the control program can be optimized according to the corresponding data records.

[0073] Embodiment 2

[0074] Please continue reading Figures 1 to 15 In this embodiment, a dry cell resuscitation instrument is also provided. Compared with the dry cell resuscitation instrument in the first embodiment, the dry cell resuscitation instrument in this embodiment can also include the following specific structure.

[0075] As an example, see Figures 2 to 5 The eccentric drive assembly includes: an eccentric wheel 48, an eccentric pad 49 and a DC motor 40. The DC motor 40 is installed on the base. The eccentric wheel 48 is connected to the DC motor 40. The eccentric pad 49 is fixed to the lower end surface of the tray 6 and is located above the eccentric wheel 48.

[0076] As an example, Fig. 9As shown, the spring assembly includes a first spring sleeve 33, a spring shaft 42, a compression spring 43 and a second spring sleeve 44, the first spring sleeve 33 is fixed on the tray 6, the second spring sleeve 44 is fixed on the base, and the first spring sleeve 33 and the second spring sleeve 44 are arranged opposite to each other, one end of the spring shaft 42 is a fixed end, and the fixed end is fixedly connected to the first spring sleeve 33, the other end of the spring shaft 42 is a free end, and the free end is inserted into the second spring sleeve 44, and the compression spring 43 is sleeved on the spring shaft 42. When the swing device drives the tray 6 to swing, the free end of the spring shaft 42 can move up and down along the second spring sleeve 44, and the compression spring 43 on the spring shaft 42 moves telescopically accordingly, and the moving position of the compression spring 43 is limited by the first spring sleeve 33 and the second spring sleeve 44.

[0077] During this process, the tray 6 drives the first connection block 21 to rotate. Since the first connection block 21 is installed on the mounting seat 22, the tray 6 can only perform a swinging motion with the mounting seat 22 as a fulcrum.

[0078] As an example, see Figure 2 , Figure 3 and Figure 11 to Figure 12 , in this embodiment, the swing device further includes: a first connecting block 21 and a mounting seat 22;

[0079] The mounting seat 22 is fixed on the base. One side of the first connecting block 21 has a rotating shaft, and the rotating shaft is inserted into a through hole formed in the mounting seat 22 . The other side of the first connecting block 21 is fixedly connected to the tray 6 .

[0080] Specifically, the resuscitation cavity is formed between the pressure relief plate 5 and the tray 6, and the pressure relief plate 5 and the tray 6 can increase the heating area of ​​the cryopreservation bag during the resuscitation process. The pressure relief plate 5 and the tray 6 are made of heat-conductive metal materials, and further, the pressure relief plate 5 is an aluminum pressure relief plate, and the tray 6 is an aluminum tray.

[0081] As an example, see Figures 13 to 15 , In another embodiment, the swing device further comprises: a second connecting block 25, a bearing seat 26, a rotating shaft 47 and a deep groove ball bearing 46;

[0082] The deep groove ball bearing 46 is installed in the bearing seat 26 , one end of the rotating shaft 47 is inserted into the deep groove ball bearing 46 , and the other end is fixedly connected to the tray 6 via the second connecting block 25 .

[0083] As an example, Figure 3 , Figure 7 , Figure 8 and Fig.10 As shown, the pressure relief connection device comprises: a pressure relief spring 11, a T-shaped connector 12, a pin 13 and a linear bearing 14;

[0084] The T-shaped connector 12 includes a horizontal portion and a vertical portion, the horizontal portion is provided with two first mounting holes 12a and two second mounting holes 12b, the second mounting holes 12b are arranged corresponding to the bolt holes provided on the pressure relief plate 5, the linear bearing 14 is installed in the first mounting hole 12a, the pressure relief spring 11 is sleeved on the pin 13, the shaft end of the pin 13 passes through the linear bearing 14 and is fixedly connected to the pressure plate 30;

[0085] The pressure plate 30 is a rectangular frame structure, and a groove is provided inside the rectangular frame structure to avoid the vertical portion of the T-shaped connector 12 . The vertical portion is fixedly connected to the pressure relief plate 5 .

[0086] When the pressure relief plate 5 contacts the items on the tray 6, if force is continued to be applied to cover the pressure plate assembly, the pressure plate 30 and the pin shaft 13 fixed to the pressure plate 30 continue to move downward due to the force, and the movement of the pressure relief plate 5 is restricted due to the resistance of the items below. The distance between the pressure relief plate 5 and the pressure plate 30 is reduced, and the pressure relief spring 11 on the pin shaft 13 is compressed.

[0087] When the objects under the pressure relief plate 5 are no longer in contact with the pressure relief plate 5, the pressure relief plate 5 is no longer subjected to force, and the elastic force of the pressure relief spring 11 is released, thereby pushing the pressure relief plate 5 away from the pressure plate 30, and the distance between the two increases.

[0088] During the process of opening and closing the cover, the linear bearing 14 cooperates with the pin shaft 13 to guide the moving direction of the pressure relief plate 5, thereby improving the stability of the up and down movement of the pressure relief plate 5.

[0089] In this embodiment, the pressing plate 30 adopts a rectangular frame structure, which can not only reduce the weight of the pressing plate assembly, but also facilitate the maintenance and replacement of the heating plate 31.

[0090] In this embodiment, the pressure relief plate 5 and the pressure plate 30 are both left-right symmetrical structures with overlapping center lines, the pressure relief connection device is distributed left-right symmetrically, and bolt holes are provided on both sides of the pressure relief plate 5, and the bolt holes are used to connect the T-shaped connector 12.

[0091] As an example, Figure 3 As shown, the base includes: an upper bottom plate 20, a lower bottom plate 24 and a hinge base 18;

[0092] The upper floor plate 20 and the lower floor plate 24 are fixedly connected via columns, and the hinge base 18 is fixed on the upper floor plate 20;

[0093] A crank 16 is installed at one end of the pressure plate 30 that is rotatably connected to the base. One end of the crank 16 is fixedly connected to the edge of the pressure plate 30, and the other end of the crank 16 is hinged to the hinge base 18 of the base through a damping hinge 17. When the pressure plate 30 rotates, the crank 16 rotates accordingly. In order to prevent the pressure plate assembly from opening too much and causing the resuscitation device to tip over, a crank limit block 34 is provided on the hinge base 18. The crank limit block 34 is used to limit the rotation angle of the crank 16. When the pressure plate assembly is opened to a certain angle, the crank 16 will be blocked by the crank limit block 34 behind or below it, and the pressure plate assembly cannot continue to open. At this time, due to the effect of the damping hinge 17, the pressure plate assembly stays in this position.

[0094] In this embodiment, the crank 16 includes a first connecting surface, a curved surface, and a second connecting surface that are sequentially connected and integrally formed. The first connecting surface is used to connect to the pressure plate 30 , and the second connecting surface is used to connect to the damping hinge 17 .

[0095] In this embodiment, the base adopts a double-layer structure design to increase the accommodating space for parts. The upper bottom plate 20 is a flat structure, and the lower bottom plate 24 is a boss structure with a high middle and low sides. The hinge base 18 on the upper bottom plate 20 is used to raise the damping hinge 17 to match the height of the tray 6, so that the pressure plate assembly can be smoothly covered on the tray 6.

[0096] In this embodiment, the vibration motor 51 can be adhered to the bottom of the tray 6 through silicone and double-sided tape, driving the tray 6 to vibrate, and driving the cells and cryopreservation liquid in the cryopreservation bag to vibrate in a small area, which can speed up the temperature transfer and reduce the cell recovery time.

[0097] As an example, Figures 3 to 5 As shown, the dry cell resuscitation instrument further includes: an L-shaped baffle 19 and a flip cover auxiliary device;

[0098] The L-shaped baffle 19 is installed on the upper bottom plate 20 and is located below the crank 16, and is used to cover the components below and behind the crank 16 to improve the visual effect;

[0099] The flip cover auxiliary device includes: a nitrogen spring push plate 36, a nitrogen spring 37, a nitrogen spring push block 38 and a slide rail 45;

[0100] The slide rail 45 is installed on the upper base plate 20 and is located between two symmetrically arranged hinge bases 18. One end of the nitrogen spring push plate 36 is installed on the slide rail 45, and the other end of the nitrogen spring push plate 36 rests on the nitrogen spring push block 38. The nitrogen spring push block 38 is fixed on the crank 16.

[0101] One end of the nitrogen spring 37 is fixedly connected to the upper bottom plate 20 via a nitrogen spring base 35 , and the other end is fixedly connected to the nitrogen spring push plate 36 .

[0102] Specifically, in the present embodiment, the eccentric drive assembly is arranged at the front end of the tray 6, and the spring assembly is arranged at the rear end of the tray 6. The DC motor 40 is mounted on the base plate 20 via the motor mounting block 41, and the eccentric wheel 48 is driven by the DC motor 40 to rotate eccentrically. When the DC motor 40 drives the eccentric wheel 48 to rotate toward the long axis, the eccentric pad 49 is lifted up, so that the front end of the tray 6 is lifted, and the compression spring 43 at the rear end of the tray 6 is compressed. When the DC motor 40 drives the eccentric wheel 48 to rotate toward the short axis, the eccentric pad 49 falls back, and the pressure on the compression spring 43 is reduced and rebounds, thereby lifting the rear end of the tray 6. Such a cycle causes the tray 6 to swing with the mounting seat 22 below it as the central fulcrum.

[0103] Similarly, in another embodiment, the tray 6 performs a rocking motion with the bearing seat 26 below the tray 6 as a central fulcrum.

[0104] When the tray 6 shakes up and down, the cell cryopreservation bag in the resuscitation chamber shakes, and the pressure relief plate 5 moves up and down. When the pressure relief plate 5 is subjected to the force applied by the tray 6, the force is converted into the elastic force of the pressure relief spring 11 through the pressure relief plate 5 pin 13; when the tray 6 does not apply force to the pressure relief plate 5, the elastic force of the pressure relief spring 11 is released, and the pressure relief plate 5 is directly pressed against the cell cryopreservation bag. The pressure relief plate 5 pin 13 is fixed to the pressure relief plate 5 through the linear bearing 14, and the linear bearing 14 is fixed to the C-shaped connector 12 to enable the pressure relief plate 5 to move stably.

[0105] As an example, Figure 2 and Figure 3 As shown, the dry cell resuscitation instrument further includes: a housing, an electromagnet 9, a micro switch 10, a suction piece 27, and a contact switch trigger 28;

[0106] The housing includes an upper cover plate 1 and an intermediate cover shell 4. The upper cover plate 1 is mounted on the pressure plate assembly and is fixedly connected to the pressure plate 30 via a connecting assembly 15. The intermediate cover shell 4 surrounds the base and the tray 6 and is connected to the lower bottom plate 24 of the base.

[0107] The electromagnet 9 and the micro switch 10 are both fixed to the upper edge of the intermediate cover 4, the suction piece 27 and the contact switch trigger 28 are both fixed on the pressure plate 30, and the suction piece 27 corresponds to the position of the electromagnet 9, and the contact switch trigger 28 corresponds to the position of the micro switch 10.

[0108] As an example, Figures 1 to 6 As shown, the dry cell resuscitation instrument further includes: a control panel 2, a barcode scanner 3, an ultraviolet lamp 7 and a cooling fan 50;

[0109] The control panel 2 and the barcode scanner 3 are respectively arranged in the windows opened in the intermediate cover 4, and the control device and the cooling fan 50 are both installed on the lower bottom plate 24, and the lower bottom plate 24 is provided with an air inlet hole;

[0110] The ultraviolet lamp 7 is installed on the inner wall of the intermediate cover 4 and is located above the tray 6. The control panel 2, the barcode scanner 3, the ultraviolet lamp 7, and the cooling fan 50 are all electrically connected to the control device.

[0111] Specifically, after the cell resuscitation is completed, the ultraviolet lamp 7 is started to disinfect the resuscitation cavity formed by the tray 6 and the pressure relief plate 5, thereby reducing the probability of infection to the cells during the resuscitation process and increasing the number of times the dry cell resuscitation instrument is used.

[0112] Specifically, the dry cell recovery instrument can be used Figure 1 The barcode scanner 3 scans the barcode on the cell freezing bag, and according to the scanned barcode record, it is more convenient to track the cell recovery status of each batch.

[0113] As an example, Figure 3 As shown, the barcode scanner 3 can be fixed on the upper base plate 20 via a barcode scanner buckle (not shown); the surface of the control panel 2 can be covered with a screen pressing block (not shown).

[0114] As an example, Figure 5 As shown, the dry cell resuscitation instrument further includes a vibration motor 51, which is fixed to a side of the tray 6 facing away from the pressure relief plate 5 and is electrically connected to the control device.

[0115] As an example, Figures 1 to 4As shown, the dry cell resuscitation instrument also includes: a liquid leakage detector (not shown in the figure) and a temperature detection device;

[0116] The tray 6 is provided with a drain port, and the liquid leakage detector is generally provided on a drain pipe, and the drain pipe is connected to the drain port.

[0117] Specifically, a drain port is provided at one corner of the tray 6, and a liquid leakage detector is used to detect whether there is too much liquid inside the tray, thereby reminding the user that the frozen storage bag is damaged.

[0118] The temperature detection device includes a first temperature sensor 8, a second temperature sensor 32, and a third temperature sensor. The first temperature sensor 8 is arranged on the supporting surface of the tray 6 to sense the temperature of the items on the tray. The second temperature sensor 32 is arranged on the side of the pressure relief plate 5 facing away from the tray 6 and on the side of the tray 6 facing away from the pressure relief plate 5 to sense the temperatures of the pressure relief plate 5 and the tray 6, respectively. The third temperature sensor is arranged in the heating plate 31 to sense the temperature of the heating plate 31.

[0119] Specifically, the dry cell recovery instrument is based on Figure 4 The heating power of the heating plate 31 is controlled by the temperature of the second temperature sensor 32 in Figure 2 The first temperature sensor 8 is used to monitor whether the cell freezing bag is placed on the tray 6 and whether it is placed in the designated area.

[0120] like Figure 4 As shown, in this embodiment, two heating plates 31 are provided on the side of the pressure relief plate 5 facing away from the tray 6, the sensor base plate is located between the two heating plates 31, and the second temperature sensor 32 is fixed to the pressure relief plate 5 and the tray 6 through the sensor base plate.

[0121] Specifically, the dry cell resuscitation instrument provided by the present invention has a door-locking structure. When the cover is closed, the contact switch trigger 28 contacts the micro switch 10, pressing the trigger point of the micro switch 10, and sending an electrical signal to the main control board to energize the electromagnet 9 to generate magnetism to attract the suction piece 27, thereby preventing the cover from being accidentally opened during the resuscitation process.

[0122] A dry cell resuscitation instrument provided by the present invention has an opening structure. When the upper cover 1 is lifted, the crank 16 rotates accordingly, and the nitrogen spring push block 38 fixed on the crank 16 transmits force to the nitrogen spring push plate 36 fixed on the slide rail 45, pushing the nitrogen spring push plate 36 to slide on the slide rail 45, so that the nitrogen spring 37 moves accordingly to be elastically released. The elastic force provided by the nitrogen spring 37 can make opening the cover more labor-saving. The damping hinge 17 is fixed to the crank 16. When the upper cover 1 is opened to a certain angle, the damping hinge 17 is blocked by the crank limit block 34 and cannot continue to open. Because of the action of the damping hinge 17, the upper cover 1 stays in this position.

[0123] Specifically, the dry cell recovery instrument Figure 6 The cooling fan 50 and Figure 3 The air inlet holes on the middle and lower bottom plate 24 form a passage to dissipate heat for the electrical components.

[0124] As an example, Figure 4 As shown, the dry cell recovery instrument may further include:

[0125] The wire cover plate 39 is located outside the crank 16 and is used for routing wires (including wires of the heating plate 31, etc.).

[0126] like Figure 1 and Figure 6 As shown, the intermediate cover shell 4 is also provided with a power socket 52, a network cable interface 23 and a USB interface 29, and the control panel 2, the barcode scanner 3, the ultraviolet lamp 7, the network cable interface 23, the USB interface 29, the heating plate 31, the DC motor 40, the cooling fan 50, the vibration motor 51, the power socket 52, the leakage detector, the first temperature sensor, the second temperature sensor and the third temperature sensor are all electrically connected to the control device.

[0127] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered exemplary and non-limiting in all respects, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations falling within the meaning and scope of the equivalent elements of the claims be included in the invention. Any reference numeral in a claim should not be considered as limiting the claim to which it relates.

[0128] In addition, it should be understood that although the present specification is described according to implementation modes, not every implementation mode contains only one independent technical solution. This description of the specification is only for the sake of clarity. Those skilled in the art should regard the specification as a whole. The technical solutions in each embodiment may also be appropriately combined to form other implementation modes that can be understood by those skilled in the art.

Claims

1. A dry cell resuscitation instrument, characterized in that: include: Base, tray, platen assembly, swing mechanism and control device; The tray is mounted on the base, and the pressing plate assembly covers the tray to form a resuscitation chamber between the pressing plate assembly and the tray; The pressure plate assembly includes a pressure relief plate, a pressure relief plate and a pressure relief connection device, one end of the pressure relief plate is rotatably connected to the base, and the pressure relief plate is connected to the pressure relief plate through the pressure relief connection device and can move up and down relative to the pressure relief plate; The pressure relief plate is arranged opposite to the bearing surface of the tray, and a heating sheet is arranged on the side of the tray facing away from the pressure relief plate and the side of the pressure relief plate facing away from the tray, and the pressure relief plate and the tray are both made of rigid heat-conducting material; The swing device includes an eccentric drive assembly and a spring assembly. The eccentric drive assembly cooperates with the spring assembly to drive the tray to swing. The heating plate and the eccentric drive assembly are both electrically connected to the control device.

2. The dry cell recovery instrument according to claim 1, characterized in that: The eccentric drive assembly comprises: an eccentric wheel, an eccentric pad and a DC motor, wherein the DC motor is mounted on the base, the eccentric wheel is connected to the DC motor, and the eccentric pad is fixed to the lower end surface of the tray and is located above the eccentric wheel; The spring assembly includes a first spring sleeve, a spring shaft, a compression spring and a second spring sleeve. The first spring sleeve is fixed on the tray, the second spring sleeve is fixed on the base, and the first spring sleeve and the second spring sleeve are arranged opposite to each other. The compression spring sleeve is arranged on the spring shaft, one end of the spring shaft is a fixed end, and the fixed end is fixedly connected to the first spring sleeve. The other end of the spring shaft is a free end, and the free end is inserted into the second spring sleeve.

3. The dry cell recovery instrument according to claim 2, characterized in that: The swing device also includes: a first connecting block and a mounting seat; The mounting seat is fixed on the base, one side of the first connecting block has a rotating shaft, the rotating shaft is inserted into a through hole provided in the mounting seat, and the other side of the first connecting block is fixedly connected to the tray.

4. The dry cell recovery instrument according to claim 2, characterized in that: The swing device also includes: a second connecting block, a bearing seat, a rotating shaft and a deep groove ball bearing; The deep groove ball bearing is installed in the bearing seat, one end of the rotating shaft is inserted into the deep groove ball bearing, and the other end is fixedly connected to the tray through the second connecting block.

5. The dry cell recovery instrument according to claim 1, characterized in that: The pressure-relieving connection device comprises: a pressure-relieving spring, a T-shaped connecting piece, a pin and a linear bearing; The T-shaped connector includes a horizontal part and a vertical part, the linear bearing is installed in a first mounting hole opened in the horizontal part, the pressure relief spring is sleeved on the pin shaft, and the shaft end of the pin shaft passes through the linear bearing and is fixedly connected to the pressure plate; The pressure plate is a rectangular frame structure, and a groove is arranged on the inner side of the rectangular frame structure to avoid the vertical part of the T-shaped connector, and the vertical part is fixedly connected to the pressure relief plate.

6. The dry cell recovery instrument according to claim 1, characterized in that: The base comprises: an upper bottom plate, a lower bottom plate and a hinge base; The upper floor plate and the lower floor plate are fixedly connected via columns, and the hinge base is fixed on the upper floor plate; A crank is installed at one end of the pressure plate rotatably connected to the base. The crank is hinged to the hinge base through a damping hinge. A crank limit block is provided on the hinge base. The crank limit block is used to limit the rotation angle of the crank.

7. The dry cell recovery instrument according to claim 6, characterized in that: Also includes: L-shaped baffle and flap assist device; The L-shaped baffle is mounted on the upper bottom plate and is located below the crank; The flip cover auxiliary device comprises: a nitrogen spring push plate, a nitrogen spring, a nitrogen spring push block and a slide rail; The slide rail is installed on the upper base plate and is located between two symmetrically arranged hinge bases. One end of the nitrogen spring push plate is installed on the slide rail, and the other end of the nitrogen spring push plate is against the nitrogen spring push block. The nitrogen spring push block is fixed on the crank. One end of the nitrogen spring is fixedly connected to the upper bottom plate through a nitrogen spring base, and the other end is fixedly connected to the nitrogen spring push plate.

8. The dry cell recovery instrument according to claim 1, characterized in that: Also includes: Housing, electromagnet, micro switch, suction piece and contact switch trigger; The housing comprises an upper cover plate and an intermediate cover shell, wherein the upper cover plate is mounted on the pressure plate assembly, and the intermediate cover shell surrounds the base and the tray and is connected to the lower bottom plate of the base; The electromagnet and the micro switch are both fixed to the upper edge of the intermediate cover shell, the suction piece and the contact switch trigger are both fixed to the pressure plate, and the suction piece corresponds to the position of the electromagnet, and the contact switch trigger corresponds to the position of the micro switch.

9. The dry cell recovery instrument according to claim 8, characterized in that: Also includes: Control panel, barcode scanner, UV lamp and cooling fan; The control panel and the barcode scanner are respectively arranged in the windows opened in the intermediate cover shell, the control device and the cooling fan are both installed on the lower bottom plate, and the lower bottom plate is provided with an air inlet hole; The ultraviolet lamp is installed on the inner wall of the intermediate cover shell and is located above the tray. The control panel, the barcode scanner, the ultraviolet lamp and the cooling fan are all electrically connected to the control device.

10. The dry cell recovery instrument according to claim 1, characterized in that: Also includes: Vibration motor, liquid leakage detector and temperature detection device; The vibration motor is fixed to a side of the tray facing away from the pressure relief plate; The tray is provided with a drain port, the liquid leakage detector is provided on a drain pipe, and the drain pipe is connected to the drain port; The temperature detection device includes a first temperature sensor, a second temperature sensor, and a third temperature sensor, wherein the first temperature sensor is arranged on the carrying surface of the tray, the second temperature sensor is arranged on the side of the pressure relief plate facing away from the tray and the side of the tray facing away from the pressure relief plate, and the third temperature sensor is arranged in the heating plate; The vibration motor, the liquid leakage detector, the first temperature sensor, the second temperature sensor and the third temperature sensor are all electrically connected to the control device.

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