Nitrogen blowing parameter adjusting method and device, detection equipment and storage medium

Abstract

The embodiment of the invention provides a nitrogen blowing parameter adjusting method and device, detection equipment and a storage medium, and the nitrogen blowing parameter adjusting method comprises the following steps: when a detected container contains a solution sample and nitrogen blowing is performed on the detected container by using a current nitrogen blowing parameter, obtaining the liquid level height of the solution sample, determining a target nitrogen blowing parameter based on the liquid level height; and under the condition that the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, the current nitrogen blowing parameter is adjusted to be the target nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is larger than or equal to that of the current nitrogen blowing parameter. The embodiment of the invention can improve the nitrogen blowing efficiency.

Description

Technical Field

[0001] The present application relates to the field of detection technology, and in particular to a nitrogen blowing parameter adjustment method, device, detection equipment and storage medium. Background Art

[0002] Nitrogen blowing is a method of blowing nitrogen into the surface of a heated sample to concentrate the sample. Usually, nitrogen is blown into the surface of a heated sample to quickly evaporate and separate the water in the sample to be processed, thereby achieving oxygen-free concentration of the sample. At the same time, the sample can be kept pure, thereby achieving the effect of rapid separation and purification. It is widely used in industries such as pesticide residue analysis, commodity inspection, food, environment, pharmaceuticals, and biological products, as well as in sample preparation for liquid phase, gas phase, and mass spectrometry analysis.

[0003] The nitrogen blowing efficiency is related to the evaporation efficiency of the sample. Blowing affects the evaporation efficiency, which belongs to the category of fluid mechanics. It is well known that fluid mechanics calculations are very complicated and it is difficult to directly calculate the theoretical value. How to improve the evaporation efficiency to improve the nitrogen blowing efficiency has become an urgent problem to be solved. Summary of the invention

[0004] The embodiments of the present application provide a nitrogen blowing parameter adjustment method, device, detection equipment and storage medium, which can improve evaporation efficiency and thus improve nitrogen blowing efficiency.

[0005] A first aspect of an embodiment of the present application provides a method for adjusting nitrogen blowing parameters, comprising:

[0006] When a solution sample is contained in a container to be tested and nitrogen is blown into the container to be tested using current nitrogen blowing parameters, a liquid level of the solution sample is obtained, and a target nitrogen blowing parameter is determined based on the liquid level;

[0007] When the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, the current nitrogen blowing parameter is adjusted to the target nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

[0008] A second aspect of an embodiment of the present application provides a nitrogen blowing parameter adjustment device, comprising:

[0009] an acquisition unit, for acquiring a liquid level height of the solution sample when a solution sample is contained in a detected container and the detected container is nitrogen-blown using current nitrogen-blowing parameters;

[0010] A determination unit, configured to determine a target nitrogen blowing parameter based on the liquid level;

[0011] The adjustment unit is used to adjust the current nitrogen blowing parameter to the target nitrogen blowing parameter when the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

[0012] A third aspect of an embodiment of the present application provides a detection device, including a processor and a memory, the memory being used to store a computer program, the computer program including program instructions, and the processor being configured to call the program instructions to execute the step instructions in the first aspect of the embodiment of the present application.

[0013] The fourth aspect of an embodiment of the present application provides a computer-readable storage medium, wherein the above-mentioned computer-readable storage medium stores a computer program for electronic data exchange, and the computer program includes program instructions, and when the program instructions are executed by a processor, the processor executes the step instructions in the first aspect of the embodiment of the present application.

[0014] The fifth aspect of the embodiments of the present application provides a computer program product, wherein the above-mentioned computer program product includes a computer program, and the computer program includes program instructions, and when the program instructions are executed by a processor, the processor executes the step instructions in the first aspect of the embodiments of the present application.

[0015] The sixth aspect of an embodiment of the present application provides a nitrogen blowing parameter adjustment system, comprising a nitrogen blowing device, a detection device and a liquid level detection device; the nitrogen blowing device is used to blow nitrogen into the detected container; the liquid level detection device is used to identify the liquid level height of the solution sample in the detected container; the detection device is used to control the nitrogen blowing parameters of the nitrogen blowing device when blowing nitrogen into the detected container according to the liquid level height of the solution sample in the detected container.

[0016] The nitrogen blowing parameter adjustment method of the embodiment of the present application, when the detected container contains a solution sample and the detected container is nitrogen-blown using the current nitrogen blowing parameters, obtains the liquid level of the solution sample; determines the target nitrogen blowing parameters based on the liquid level, and when the target nitrogen blowing parameters are different from the current nitrogen blowing parameters, adjusts the current nitrogen blowing parameters to the target nitrogen blowing parameters, and the evaporation efficiency of the target nitrogen blowing parameters is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameters. In the embodiment of the present application, the liquid level of the solution sample can be obtained, and the nitrogen blowing parameters can be adjusted according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency. BRIEF DESCRIPTION OF THE DRAWINGS

[0017] In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present application. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0018] Figure 1 It is a flow chart of a method for adjusting nitrogen blowing parameters provided in an embodiment of the present application;

[0019] Figure 2 It is a structural schematic diagram of a centrifuge tube provided in an embodiment of the present application;

[0020] Figure 3 It is a schematic diagram of the air outlet angle of a nitrogen blowing air duct and the air flow rotation of a centrifugal tube provided in an embodiment of the present application;

[0021] Figure 4 This is a schematic diagram of the variation range of the air outlet angle of a nitrogen blowing air duct provided in an embodiment of the present application;

[0022] Figure 5 It is a schematic diagram of dividing the liquid level into several height intervals provided in an embodiment of the present application;

[0023] Figure 6 This is a flow chart of setting the wind speed and wind outlet angle according to the current liquid level provided in an embodiment of the present application;

[0024] Figure 7a It is a distribution diagram of sequence numbers and random probabilities corresponding to a height interval provided in an embodiment of the present application;

[0025] Figure 7b This is a distribution diagram of sequence numbers and random probabilities corresponding to another height interval provided in an embodiment of the present application;

[0026] Figure 7c This is a distribution diagram of sequence numbers and random probabilities corresponding to another height interval provided in an embodiment of the present application;

[0027] Figure 7d This is a distribution diagram of sequence numbers and random probabilities corresponding to another height interval provided in an embodiment of the present application;

[0028] Figure 7e This is a distribution diagram of sequence numbers and random probabilities corresponding to another height interval provided in an embodiment of the present application;

[0029] Figure 8 It is a specific flow diagram of a multi-channel fully automatic nitrogen blowing method provided in an embodiment of the present application;

[0030] Fig. 9 It is a structural schematic diagram of a nitrogen blowing parameter adjustment device provided in an embodiment of the present application;

[0031] Fig.10 It is a structural schematic diagram of a detection device provided in an embodiment of the present application. DETAILED DESCRIPTION

[0032] The following will be combined with the drawings in the embodiments of the present application to clearly and completely describe the technical solutions in the embodiments of the present application. Obviously, the described embodiments are only part of the embodiments of the present application, not all of the embodiments. Based on the embodiments in the present application, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of this application.

[0033] The terms "first", "second", etc. in the specification and claims of this application and the above-mentioned drawings are used to distinguish different objects, rather than to describe a specific order. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusions. For example, a process, method, system, product or device that includes a series of steps or units is not limited to the listed steps or units, but optionally includes steps or units that are not listed, or optionally includes other steps or units inherent to these processes, methods, products or devices.

[0034] Reference to "embodiments" in this application means that a particular feature, structure, or characteristic described in conjunction with the embodiments may be included in at least one embodiment of the present application. The appearance of the phrase in various locations in the specification does not necessarily refer to the same embodiment, nor is it an independent or alternative embodiment that is mutually exclusive with other embodiments. It is explicitly and implicitly understood by those skilled in the art that the embodiments described in this application may be combined with other embodiments.

[0035] The detection device involved in the embodiments of the present application is a device with data processing and computing capabilities, and may be a mobile phone, a tablet computer, a notebook computer, an ultra-mobile personal computer (UMPC), a netbook, a digital signal processor, a microcontroller unit (MCU), etc.

[0036] The nitrogen blowing parameter adjustment method of the embodiment of the present application can obtain the liquid level of the solution sample, and can adjust the nitrogen blowing parameters according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency.

[0037] Nitrogen blowing: Usually, nitrogen is blown into the surface of the heated sample to quickly evaporate and separate the water in the sample to be processed, thereby achieving oxygen-free concentration of the sample. At the same time, it can keep the sample pure, thus achieving the effect of rapid separation and purification. It is widely used in pesticide residue analysis, commodity inspection, food, environment, pharmaceuticals, biological products and other industries, as well as in sample preparation for liquid phase, gas phase and mass spectrometry analysis.

[0038] Near dry: An indicator that measures the concentration of a sample, meaning that the solution is close to dry. There is no specific numerical standard for near dry, and it is a vague definition. Different volume standards are set according to different samples and different business needs. For example, a solution volume of less than 100 microliters (ul) is considered to have reached the near dry standard.

[0039] The embodiment of the present application provides a nitrogen blowing parameter adjustment system, which includes a nitrogen blowing device, a detection device and a liquid level detection device;

[0040] Among them, the nitrogen blowing equipment can blow nitrogen into the container to be tested; the liquid level detection device can identify the liquid level height of the solution sample in the container to be tested; the detection equipment can control the nitrogen blowing parameters of the nitrogen blowing equipment when blowing nitrogen into the container to be tested according to the liquid level height of the solution sample in the container to be tested.

[0041] The nitrogen blowing equipment may include a nitrogen blowing air duct and a motor, and the nitrogen blowing parameters may include an air outlet angle and a wind speed. The motor may drive the nitrogen blowing air duct to rotate, thereby adjusting the air outlet angle of the nitrogen blowing air duct to adapt to the adjustment of the air outlet angle at different liquid level heights, thereby improving the evaporation efficiency of the solution sample and further improving the nitrogen blowing efficiency.

[0042] A flow valve may be provided in the nitrogen blow-out duct, and the flow valve may independently control the gas flow in the nitrogen blow-out duct, thereby adjusting the wind speed of the nitrogen blow-out duct.

[0043] The liquid level detection device may include a camera or a liquid level detection sensor. The image of the detected container can be captured by the camera, thereby identifying the liquid level of the solution sample in the detected container in the image. The liquid level of the solution sample in the detected container can also be identified by the liquid level detection sensor. When the liquid level detection device includes a liquid level detection sensor, the liquid level detection device can periodically obtain the liquid level of the solution sample. When the liquid level detection device includes a camera, the liquid level detection device can periodically capture the image of the detected container, and the detection device can obtain the image of the detected container, thereby identifying the liquid level of the solution sample in the detected container.

[0044] In the embodiment of the present application, the liquid level of the solution sample in the detected container can be identified, and the nitrogen blowing parameters can be adjusted according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency.

[0045] The container to be detected can be a transparent container, such as a centrifuge tube (such as a plastic centrifuge tube or a glass centrifuge tube), a test tube, a solvent bottle, a flask, etc.

[0046] The detection device can be connected to the camera for communication (wired communication connection or wireless communication connection), and the image captured by the camera can be transmitted to the detection device for detection. The detection device can detect whether the solution sample in the image meets the near-dry standard.

[0047] The liquid level of the solution sample is the height between the liquid level of the solution sample and the bottom of the container to be inspected. The image of the container to be inspected taken by the camera can be analyzed to identify the liquid level of the solution sample in the image.

[0048] The detection device can also calculate the solution volume of the solution sample in the image based on the liquid level of the solution sample in the image. The solution volume of the solution sample is the volume of the solution sample in the detected container. The image taken by the camera containing the detected container can be analyzed to identify the liquid level of the solution sample in the image, and the solution volume of the solution sample in the image can be calculated based on the liquid level.

[0049] The detection equipment is a device with image processing and image analysis capabilities.

[0050] The focal length of the camera can be set to capture an image containing the entire inspected container. When the camera captures an image containing at least two inspected containers, the focal length of the camera can be set to capture a complete image containing at least two inspected containers.

[0051] See also Figure 1 , Figure 1 It is a flow chart of a method for adjusting nitrogen blowing parameters provided in an embodiment of the present application. Figure 1 The method can be applied to the above nitrogen blowing parameter adjustment system. Figure 1 As shown, the method may include the following steps.

[0052] 101. When a solution sample is contained in a container to be tested and nitrogen is blown into the container to be tested using current nitrogen blowing parameters, a testing device obtains a liquid level height of the solution sample.

[0053] In the embodiment of the present application, nitrogen blowing on the detected container means using the nitrogen blowing air pipe corresponding to the detected container to blow nitrogen on the detected container so that the solution sample in the detected container evaporates quickly. The current nitrogen blowing parameter is the nitrogen blowing parameter of the nitrogen blowing air pipe corresponding to the detected container currently set.

[0054] The detection device can control the air outlet speed (can be referred to as wind speed) and the air outlet angle of the nitrogen blowing air outlet pipe, thereby controlling the nitrogen blowing parameters for nitrogen blowing the container under detection. The nitrogen blowing parameters can include wind speed and air outlet angle.

[0055] The detection device obtains the liquid level of the solution sample and can capture an image of the detected container through a camera, thereby identifying the liquid level of the solution sample in the detected container in the image.

[0056] Optionally, in step 101, the detection device obtains the liquid level of the solution sample, which may include the following steps:

[0057] The detection device acquires an image containing the container to be detected and identifies the liquid level height of the solution sample in the image.

[0058] The detection device can obtain an image of the detected container taken by the camera. The solution sample in the image refers to the solution sample in a certain detected container in the image. The liquid level of the solution sample refers to the height between the liquid level of the solution sample in a certain detected container and the bottom of the detected container.

[0059] An image containing a detected container means that the image contains the detected container. Specifically, the image may contain one detected container or at least two detected containers, each of which may contain a solution sample. For each detected container, the nitrogen blowing parameters may be adjusted in the manner of steps 101 to 103.

[0060] When the image includes at least two containers to be inspected, the type of the solution sample in each container to be inspected may be the same or different, which is not limited in the embodiment of the present application.

[0061] When the container under test contains a solution sample and nitrogen is blown into the container under test using the current nitrogen blowing parameters, the detection device in step 101 obtains the liquid level of the solution sample, step 102 and step 103 are executed.

[0062] Optionally, the detection device obtains the liquid level of the solution sample, which may include the following steps:

[0063] The detection device obtains an image containing the detected container captured according to a set capturing cycle, and identifies the liquid level of the solution sample in the image.

[0064] In the embodiment of the present application, the camera can take pictures according to a set shooting cycle. The focal length of each shooting is equal, and the distance between the camera and the detected container is equal during each shooting.

[0065] The shooting cycle can be set in advance. For example, the shooting cycle can be set to 30 seconds or 1 minute. The setting of the shooting cycle is determined by the time of executing step 102. Generally speaking, the shooting cycle is set to be greater than or equal to the time used to execute step 102. For example, if the shooting cycle is 30 seconds, the camera captures an image every 30 seconds.

[0066] 102. The detection device determines the target nitrogen blowing parameters based on the liquid level.

[0067] In one possible embodiment, for the same solution sample, different target nitrogen blowing parameters can be determined based on different liquid level heights. For example, as the liquid level decreases, the wind outlet angle and wind speed are increased. The wind outlet angle can be the angle between the nitrogen blow outlet pipe and the horizontal plane. The wind outlet angle and wind speed can be dynamically adjusted to ensure that the cyclone energy of the gas coming out of the nitrogen blow outlet pipe is sufficient to reach the liquid level, thereby improving the evaporation efficiency.

[0068] In another possible embodiment, the target nitrogen blowing parameter with the highest evaporation efficiency can be selected according to the evaporation efficiency of the nitrogen blowing parameter determined historically. The nitrogen blowing parameter determined historically can be a randomly generated nitrogen blowing parameter, or can be determined according to the corresponding relationship between the liquid level and the wind outlet angle and the corresponding relationship between the liquid level and the wind speed. Among them, the corresponding relationship between the liquid level and the wind outlet angle can be: as the liquid level decreases, the wind outlet angle increases (the wind outlet angle can be the angle between the nitrogen blowing air outlet pipe and the horizontal plane). The corresponding relationship between the liquid level and the wind speed can be: as the liquid level decreases, the wind speed increases.

[0069] 103. When the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, the detection device adjusts the current nitrogen blowing parameter to the target nitrogen blowing parameter.

[0070] Before adjustment, the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

[0071] When the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, the detection device may adjust the current nitrogen blowing parameter to the target nitrogen blowing parameter, thereby improving the evaporation efficiency.

[0072] In the embodiment of the present application, the liquid level of the solution sample in the image containing the detected container can be identified, and the nitrogen blowing parameters can be adjusted according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency.

[0073] Optional, Figure 1 The method shown may also include the following steps:

[0074] When the target nitrogen blowing parameter is the same as the current nitrogen blowing parameter, the current nitrogen blowing parameter is maintained unchanged.

[0075] When the target nitrogen blowing parameter is the same as the current nitrogen blowing parameter, the evaporation efficiency of the target nitrogen blowing parameter is the same as the evaporation efficiency of the current nitrogen blowing parameter, and there is no need to adjust the current nitrogen blowing parameter.

[0076] Optionally, the detection device identifies the liquid level of the solution sample in the image, which may include the following steps:

[0077] (11) The detection device inputs the image into a deep learning model to obtain a pixel unit value of the liquid surface position of the solution sample;

[0078] (12) The detection device determines the liquid level height corresponding to the pixel unit value of the liquid level position according to the corresponding relationship between the pixel unit value and the height.

[0079] In an embodiment of the present application, after the image is input into the deep learning model, the deep learning model can output the pixel unit value of the liquid level position of the solution sample. The deep learning model can be a trained model. The deep learning model can identify the liquid level position of the solution sample in the container to be detected in the image and output the pixel unit value of the liquid level position.

[0080] The pixel unit value of the liquid surface position may be the difference in pixel coordinates between the liquid surface position of the container to be detected and the bottom position of the container to be detected. Specifically, after the image is input into the deep learning model, the deep learning model can identify the pixel coordinates of the liquid surface position of the solution sample in the container to be detected in the image, identify the pixel coordinates of the bottom position of the container to be detected in the image, and subtract the ordinates of the two pixel coordinates to obtain the pixel unit value of the liquid surface position of the solution sample in the container to be detected.

[0081] The correspondence between the pixel unit value and the height is related to the image resolution and the focal length of the camera. When the image resolution and the focal length of the camera are constant, the pixel unit value is proportional to the height. For example, the height corresponding to a pixel unit value is 0.00085cm. The pixel unit can be represented by Px. If the pixel unit value is 10000Px, the corresponding height is 8.5cm.

[0082] Optionally, the training process of the deep learning model may specifically include the following steps:

[0083] (21) When a solution sample is contained in a container to be inspected and nitrogen is blown into the container to be inspected, the inspection device periodically acquires an image containing the container to be inspected;

[0084] (22) When the liquid surface position of the image is manually marked, the detection device pre-processes the manually marked image to obtain a plurality of sample images corresponding to the image;

[0085] (23) The detection device uses the multiple sample images and the corresponding liquid surface positions as training samples, and uses the training samples to perform model training to obtain the deep learning model.

[0086] In the embodiment of the present application, step (21) can be performed by taking an image of the inspected container by a camera. The specific implementation of step (21) can refer to the above step 101, which will not be described in detail here.

[0087] In step (21), different types of solution samples can be configured in the containers to be tested. Taking the nitrogen blowing parameter adjustment system as an example, 8 different types of solution samples can be configured in 8 containers to be tested.

[0088] Step (22) can obtain multiple images through step (21), and generate multiple sample images corresponding to each image, thereby creating more sample images and improving the generalization ability of the trained deep learning model.

[0089] Step (23) can input the sample image into the model for training. The training of the model can be carried out in a supervised manner, wherein the liquid surface position of the sample image is the label of the sample and the sample image is the input of the model. The model can calculate the training loss and optimize the model according to the training loss (for example, updating the weight parameters of the model), thereby obtaining a trained model, i.e., the above-mentioned deep learning model. The deep learning model can include a convolutional neural network, and the convolutional neural network can include multiple convolutional layers.

[0090] Preprocessing may include but is not limited to at least one of the following: changing the size of the image, filtering the image (for example, Gaussian filtering, median filtering, mean filtering, etc.), grayscale processing the image, equalizing the image, compressing the image, etc.

[0091] Based on the above nitrogen blowing parameter adjustment system, the training process of the deep learning model may specifically include the following steps:

[0092] Step 1: Prepare the solution sample and blow it with nitrogen using a nitrogen blowing device. The camera captures an image every 30 seconds until it is completely blown dry.

[0093] Step 2: Manually mark the image collected in the first step and mark the position of the liquid surface;

[0094] Step 3: Preprocess the labeled images and perform data enhancement;

[0095] Step 4: Extract data features based on convolutional neural network and perform model training.

[0096] Optionally, in step 102, the detection device determines the target nitrogen blowing parameters based on the liquid level, which may specifically include the following steps:

[0097] (31) a detection device obtains the type of the solution sample;

[0098] (32) The detection device determines target nitrogen blowing parameters based on the type of the solution sample and the liquid level height.

[0099] In the embodiments of the present application, since different types of solutions have different properties, if the same set of nitrogen blowing parameters is used for different types of solutions, the effects may be uneven. Different nitrogen blowing parameters can be set for different types of solutions in the same height range, which is conducive to compatibility with different solutions and can take into account efficiency.

[0100] Optionally, step (32) may include the following steps:

[0101] (321) when there are nitrogen blowing parameters corresponding to the type of the solution sample, the detection device determines a target nitrogen blowing parameter corresponding to the liquid level from the nitrogen blowing parameters corresponding to the type of the solution sample;

[0102] (322) When there are no nitrogen blowing parameters corresponding to the type of the solution sample and there are nitrogen blowing parameters corresponding to the first type, the detection device determines the target nitrogen blowing parameters corresponding to the liquid level height from the nitrogen blowing parameters corresponding to the first type; the first type and the type of the solution sample belong to the same large category set, or the similarity between the first type and the type of the solution sample reaches a second threshold.

[0103] In the embodiment of the present application, the existence of nitrogen blowing parameters corresponding to the type of the solution sample means that the nitrogen blowing parameters corresponding to the type of the solution sample have been stored. For example, if a solution sample of the same type as the solution sample has been tested at least once, the nitrogen blowing parameters corresponding to the type of the solution sample can be saved.

[0104] Similarity refers to the similarity of sample characteristics of two types of solution samples. The higher the similarity between the two, the closer their properties are. The similarity between different solution samples can be determined based on at least one characteristic of the solution sample, such as density, viscosity, boiling point, vapor pressure, surface tension, etc. The second threshold can be set in advance.

[0105] The absence of nitrogen blowing parameters corresponding to the type of the solution sample means that the nitrogen blowing parameters corresponding to the type of the solution sample are not stored. For example, a solution sample of the same type as the solution sample has not been tested.

[0106] Types with similar properties can be classified into the same large category set. For example, the first type and the second type have similar properties and both belong to the same large category set. When there is no nitrogen blowing parameter corresponding to the second type and there is a nitrogen blowing parameter corresponding to the first type, when nitrogen blowing is performed on the second type of solution sample, the target nitrogen blowing parameter corresponding to the liquid level height of the second type of solution sample can be determined from the nitrogen blowing parameter corresponding to the first type, thereby improving the nitrogen blowing efficiency.

[0107] Optionally, in step 102, the detection device determines the target nitrogen blowing parameters based on the liquid level, which may specifically include the following steps:

[0108] (41) The detection device determines the height interval corresponding to the liquid level according to the liquid level; wherein the detected container is pre-divided into at least two height intervals;

[0109] (42) The detection device determines the target nitrogen blowing parameters according to the height range corresponding to the liquid level height.

[0110] In the embodiment of the present application, the container to be inspected is pre-divided into at least two height intervals, and each height interval is respectively provided with corresponding nitrogen blowing parameters. The height interval corresponding to the liquid level refers to the height interval into which the liquid level falls.

[0111] Optionally, the nitrogen blowing parameters include an air outlet angle and a wind speed, and step (42) may include the following steps:

[0112] (421) When the height interval corresponding to the liquid level height is a first height interval, the detection device determines a first target nitrogen blowing parameter; wherein the wind speed of the first target nitrogen blowing parameter is the same as the wind speed of the current nitrogen blowing parameter, and the wind outlet angle of the first target nitrogen blowing parameter changes periodically within a set angle range;

[0113] (422) When the height interval corresponding to the liquid level height is the second height interval, the detection device determines a second target nitrogen blowing parameter; wherein the second target nitrogen blowing parameter is a historical nitrogen blowing parameter corresponding to the second height interval, or the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method; and the upper limit value of the first height interval is less than or equal to the lower limit value of the second height interval.

[0114] In the embodiment of the present application, the upper limit of the first height interval is less than or equal to the lower limit of the second height interval, that is, the distance between the first height interval and the nitrogen outlet is greater than the distance between the second height interval and the nitrogen outlet. Exemplarily, when the liquid level is low, the nitrogen outlet is far from the liquid surface, and it is difficult to generate a vortex on the liquid surface by increasing the wind speed. At this time, the wind speed may not be changed or may be adjusted to the maximum wind speed and remain unchanged, and only the blowing angle may be cyclically adjusted to improve the evaporation efficiency of the sample solution by sweeping the wind.

[0115] Optionally, the inner diameter of the container under test in the second height interval is greater than the inner diameter of the container under test in the first height interval. The container under test may have a larger inner diameter in the upper half (second height interval) and a smaller inner diameter in the lower half (first height interval).

[0116] When nitrogen is blown into the container to be tested, the solution sample in the container to be tested forms an annular fluid. The annular fluid has lower flow resistance, higher heat transfer coefficient, and better gas-liquid separation. In order to ensure higher evaporation efficiency, a spiral airflow needs to be formed in the container to be tested. And the airflow intensity needs to reach the intensity that makes the liquid surface rotate, so as to redistribute the gas-liquid interface and be more conducive to evaporation.

[0117] In the first height interval, the liquid level is low, the inner diameter of the container being tested is small, the cyclonic energy of the gas coming out of the nitrogen blowing duct is attenuated, and a spiral airflow cannot be formed. The wind speed of the nitrogen blowing parameter can be controlled to remain unchanged, and the outlet angle of the nitrogen blowing parameter can be controlled to change periodically within the set angle range. The dynamic sweeping strategy is used to improve the evaporation efficiency. In the second height interval, the liquid level is high, the inner diameter of the container being tested is large, and the gas coming out of the nitrogen blowing duct can form a spiral airflow. However, as the liquid level decreases, the energy of the spiral airflow decays. The historical nitrogen blowing parameters corresponding to the second height interval or the randomly generated nitrogen blowing parameters can be used to find nitrogen blowing parameters with higher evaporation efficiency.

[0118] The historical nitrogen blowing parameter corresponding to the second height interval may be a nitrogen blowing parameter with the highest evaporation efficiency in the historical nitrogen blowing parameter set corresponding to the second height interval, or may be a nitrogen blowing parameter randomly selected from the historical nitrogen blowing parameter set.

[0119] Optionally, the set angle range is 30° to 90°.

[0120] Optionally, the inner diameter of the inspected container in the second height interval is greater than the inner diameter of the inspected container in the first height interval.

[0121] Optionally, within the first height interval, the inner diameter of the detected container is positively correlated with the liquid level height.

[0122] In the embodiment of the present application, the inner diameter of the detected container is positively correlated with the liquid level in the first height interval. In the first height interval, as the liquid level increases, the inner diameter of the detected container also increases. In the first height interval, the detected container is similar to a cone or a semicircle.

[0123] Take the container to be inspected as an example, the upper part is cylindrical and the bottom is conical. Figure 2 , Figure 2 Schematic diagram of the structure of a centrifuge tube provided in the embodiment of the present application. Figure 2 As shown, the airflow enters the centrifuge tube in a spiral manner, and after reaching the liquid level, it flows upward out of the centrifuge tube from the center of the cyclone, taking away the evaporated liquid.

[0124] In a possible embodiment, the second height interval is a sub-interval of the height interval corresponding to the cylinder, that is, the second height interval is included in the height interval corresponding to the cylinder. The first height interval is a sub-interval of the height interval corresponding to the cone, that is, the first height interval is included in the height interval corresponding to the cone.

[0125] In another possible embodiment, the second height interval is a height interval corresponding to a cylinder, and the first height interval is a height interval corresponding to a cone.

[0126] In another possible embodiment, the second height interval is a sub-interval of the height interval corresponding to the cylinder, that is, the second height interval is included in the height interval corresponding to the cylinder. The first height interval is the height interval corresponding to the cone.

[0127] In an embodiment of the present application, the historical nitrogen blowing parameter set corresponding to the second height interval includes all nitrogen blowing parameters historically determined for the liquid level within the second height interval, or the historical nitrogen blowing parameter set corresponding to the second height interval includes the top N historical nitrogen blowing parameters with the highest evaporation efficiency historically determined for the liquid level within the second height interval. Wherein, N can be an integer greater than or equal to 0. When N=0, the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method. When N is greater than or equal to 1, the second target nitrogen blowing parameter is the nitrogen blowing parameter with the highest evaporation efficiency in the historical nitrogen blowing parameter set corresponding to the second height interval, or the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method.

[0128] Among them, any two parameters in the historical nitrogen blowing parameter set are different from each other.

[0129] Optionally, when the number of parameters in the historical nitrogen blowing parameter set is less than a first threshold, the historical nitrogen blowing parameter set corresponding to the second height interval includes all nitrogen blowing parameters historically determined for the liquid level within the second height interval;

[0130] When the number of parameters in the historical nitrogen blowing parameter set is greater than or equal to the first threshold, the historical nitrogen blowing parameter set corresponding to the second height interval includes N historical nitrogen blowing parameters ranked top N in evaporation efficiency historically determined at the liquid level within the second height interval, where N is equal to the first threshold.

[0131] In the embodiment of the present application, the first threshold value can be preset. The first threshold value can be set to an integer greater than 2. For example, the first threshold value can be set to 10.

[0132] Among them, after each execution of step 102 when the liquid level height is within the second height interval, if the obtained target nitrogen blowing parameter is a new nitrogen blowing parameter (the liquid level height is within the second height interval, and the set nitrogen blowing parameter has never appeared before), and the number of parameters in the historical nitrogen blowing parameter set corresponding to the second height interval is less than the first threshold, then the new nitrogen blowing parameter is added to the historical nitrogen blowing parameter set corresponding to the second height interval.

[0133] The maximum number of parameters in the historical nitrogen blowing parameter set can be set to a first threshold. After each execution of step 102 in the second height interval of the liquid level, if a new nitrogen blowing parameter is obtained, and the number of parameters in the historical nitrogen blowing parameter set corresponding to the second height interval is equal to the first threshold, the evaporation efficiency of the new nitrogen blowing parameter is calculated; if the evaporation efficiency of the new nitrogen blowing parameter is lower than the evaporation efficiency of all historical nitrogen blowing parameters in the above historical nitrogen blowing parameter set, the historical nitrogen blowing parameter set corresponding to the second height interval is maintained unchanged; if the evaporation efficiency of the new nitrogen blowing parameter is higher than the historical nitrogen blowing parameter with the lowest evaporation efficiency in the above historical nitrogen blowing parameter set, the historical nitrogen blowing parameter with the lowest evaporation efficiency in the above historical nitrogen blowing parameter set is replaced by the new nitrogen blowing parameter to obtain a new historical nitrogen blowing parameter set corresponding to the second height interval, which can ensure that the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set corresponding to the second height interval are a set of N historical nitrogen blowing parameters ranked top N in terms of evaporation efficiency determined historically in the second height interval.

[0134] Evaporation efficiency is the change in solution volume per unit time. For example, an image is taken every one minute. For each image, after executing step 102 and identifying the liquid level of the solution sample in the image, the solution volume of the solution sample in the image can be calculated based on the liquid level. The evaporation efficiency can be calculated by counting the change in solution volume over a period of time. For example, the solution volume of the solution sample in the detected container at time T1 is V1, and the solution volume of the solution sample in the detected container at time T2 is V2, then the evaporation efficiency W = (V1-V2) / (T2-T1). The evaporation efficiency of a certain nitrogen blowing parameter refers to the evaporation efficiency measured under the nitrogen blowing parameter.

[0135] When the second height interval is a sub-interval of the height interval corresponding to the cylinder, the height interval corresponding to the cylinder can be divided into multiple second height intervals, and each second height interval can correspond to a historical nitrogen blowing parameter set. It should be noted that the number of historical nitrogen blowing parameters corresponding to each second height interval is not necessarily the same.

[0136] If a spiral downward airflow is formed in the centrifuge tube, the outlet angle of the nitrogen blow-out duct needs to meet certain conditions. Obviously, it is impossible to form a spiral airflow by blowing vertically downward. The outlet angle of the nitrogen blow-out duct needs to meet certain conditions. The airflow needs to rotate along the direction that is as tangent as possible to the arc side of the centrifuge tube cross section. While rotating, the airflow also needs a vertical downward velocity component. Therefore, the nitrogen blow-out duct needs to be tilted downward at a certain angle. Please refer to Figure 3 , Figure 3 It is a schematic diagram of the air outlet angle of a nitrogen blowing air duct and the air flow rotation of a centrifuge tube provided in an embodiment of the present application.

[0137] The friction of the tube wall and the lowering of the liquid level in the tube will cause the energy of the cyclone to decay when it reaches the liquid level, and the evaporation efficiency will decrease when the wind angle and wind speed remain unchanged. After the liquid level reaches the conical area at the bottom of the centrifuge tube, the drop in the liquid level will be accompanied by a decrease in the cross-sectional radius. The decrease in radius will weaken the cyclone until it is completely destroyed, resulting in a stable gas-liquid interface, which is not conducive to further concentration and evaporation.

[0138] In order to improve the evaporation efficiency, the following two problems need to be solved:

[0139] A. As the liquid level drops, the cyclone energy decays. B. A cyclone cannot form in the conical area of ​​the centrifuge tube.

[0140] Regarding question A, the wind angle and wind speed can be adjusted dynamically to ensure that the cyclone energy is sufficient to reach the liquid level. Regarding question B, when a cyclone cannot be formed, a dynamic wind sweeping strategy can be used to improve evaporation efficiency.

[0141] A flow valve can be set in the nitrogen blow-out duct, and the flow valve can independently control the gas flow in the nitrogen blow-out duct. The nitrogen blow-out duct can be driven by the motor to rotate within a set angle range. The set angle range can be that the angle between the nitrogen blow-out duct and the horizontal plane is in the range of 30 degrees to 90 degrees. Figure 4 , Figure 4 Schematic diagram of the variation range of the outlet angle of a nitrogen blowing air duct provided in an embodiment of the present application. Figure 4 As shown, the angle between the nitrogen blowing duct and the horizontal plane can vary within the range of 30°-90°.

[0142] The outlet angle of the first target nitrogen blowing parameter changes periodically, and the outlet angle of the first target nitrogen blowing parameter changes periodically within the above-mentioned set angle range. For example, an angular velocity (for example, 1° per second) can be set for the motor, so that the angle between the nitrogen blowing air outlet pipe and the horizontal plane direction is cyclically swept within the set angle range. The angular velocity can be set in advance, and the magnitude of the angular velocity can be flexibly set as needed.

[0143] Optionally, in the above step (422), the detection device determines the second target nitrogen blowing parameter, which may specifically include the following steps:

[0144] (4221) the detection device determines a set of historical nitrogen blowing parameters corresponding to the second altitude interval;

[0145] (4222) The detection device selects the second target nitrogen purge parameter as one of or any one of the historical nitrogen purge parameters in the historical nitrogen purge parameter set according to a first probability, and selects the second target nitrogen purge parameter as a nitrogen purge parameter generated by a random method according to a second probability; the sum of the first probability and the second probability is equal to 1.

[0146] The first probability is a value between 0 and 1, the second probability is a value between 0 and 1, and the sum of the first probability and the second probability is equal to 1.

[0147] Optionally, step (4222) may specifically include: when the number of parameters in the historical nitrogen blowdown parameter set is greater than or equal to a first threshold, the detection device selects the second target nitrogen blowdown parameter as the historical nitrogen blowdown parameter with the highest evaporation efficiency in the historical nitrogen blowdown parameter set according to a first probability, and selects the second target nitrogen blowdown parameter as a nitrogen blowdown parameter generated by a random method according to a second probability; the first probability is greater than the second probability.

[0148] Optionally, in the above step (422), the detection device determines the second target nitrogen blowing parameter, and may also include the following steps: when the number of parameters in the historical nitrogen blowing parameter set is less than the first threshold, the detection device determines the second target nitrogen blowing parameter as a nitrogen blowing parameter generated by a random method.

[0149] In the embodiment of the present application, the first threshold value can be set in advance. The first threshold value can be set to an integer greater than 2. For example, the first threshold value can be set to 10. When the number of parameters in the historical nitrogen blowing parameter set is equal to the first threshold value, the historical nitrogen blowing parameter set is a set of historical nitrogen blowing parameters with the top N evaporation efficiencies historically determined in the second height interval of the liquid level, and N is equal to the first threshold value.

[0150] If N is equal to the first threshold, it indicates that the number of historical nitrogen blowing parameters determined is large, and the credibility of the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set is relatively high. According to the first probability, the second target nitrogen blowing parameter can be selected as the nitrogen blowing parameter with the highest evaporation efficiency in the historical nitrogen blowing parameter set, and according to the second probability, the second target nitrogen blowing parameter is selected as the nitrogen blowing parameter generated by a random method. If N is less than the first threshold, it indicates that the number of historical nitrogen blowing parameters determined in history is small, and the credibility of the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set is relatively low. At this time, the second target nitrogen blowing parameter generated by a random method can be used.

[0151] The first probability is a value between 0 and 1, the second probability is a value between 0 and 1, and the sum of the first probability and the second probability is equal to 1.

[0152] The first probability and the second probability can be configured. The first probability and the second probability can be configured as set values ​​(for example, the first probability is configured as 0.8 and the second probability is configured as 0.2), or can be determined according to a set of historical nitrogen blowing parameters. If the N historical nitrogen blowing parameters in the set of historical nitrogen blowing parameters do not change within a first time period (the first time period can be a preset value) before executing step (422), indicating that the evaporation efficiency of the nitrogen blowing parameters generated by the random method is poor, the first probability can be increased based on the set value (the first probability can be adjusted to 1 at the highest) and the second probability can be lowered (the second probability can be adjusted to 0 at the lowest), thereby improving the evaporation efficiency.

[0153] Optionally, the nitrogen blowing parameters generated by the random method include:

[0154] The outlet angle of the nitrogen blowing parameter is randomly generated within the set angle range;

[0155] The wind speed of the nitrogen blowing parameter is generated according to the following formula:

[0156] v=P*v max ;

[0157] Wherein, v is the wind speed of the nitrogen blowing parameter, v max is the upper limit of wind speed of nitrogen blowing parameters, and P is the random probability.

[0158] In the embodiment of the present application, the set angle range may be a pre-set range. For example, the set angle range may be a range of 30 degrees to 90 degrees between the angle between the nitrogen outlet duct and the horizontal plane.

[0159] v max is the upper limit of the wind speed of the nitrogen blowing parameter, v max It is related to the pipeline pressure of the nitrogen blowing air duct. P can be a randomly generated probability value, and the range of P is 0-1.

[0160] Optional,

[0161] Wherein, P is a random probability, R is a random number between 0 and 1, and n is a serial number corresponding to the second height interval; n is negatively correlated with the distance from the second height interval to the nitrogen outlet.

[0162] In the embodiment of the present application, the second height interval is a sub-interval of the height interval corresponding to the cylinder. The height interval corresponding to the cylinder can be divided into a plurality of second height intervals, and the sequence numbers corresponding to each second height interval are also different from each other. The smaller n is, the farther the distance from the second height interval to the nitrogen outlet is. The nitrogen outlet refers to the outlet of the nitrogen outlet duct.

[0163] In the above formula, the smaller n is, the greater the probability that P is a high probability value (for example, the probability that P is greater than 0.8), and the greater the probability of generating a higher wind speed, thereby increasing the evaporation efficiency as much as possible.

[0164] In the embodiment of the present application, the height of the nitrogen blowing duct is fixed, and the nitrogen blowing parameters that can be changed are the wind angle and wind speed. However, during the evaporation process, the height of the nitrogen blowing duct relative to the liquid level continues to increase, resulting in the energy attenuation of the spiral airflow reaching the liquid surface. In order to maintain a high evaporation efficiency, it is necessary to dynamically adjust the wind angle and wind speed as the liquid level changes. The embodiment of the present application designs a set of search methods for nitrogen blowing parameters (including wind angle and wind speed) based on probability distribution, and the steps are as follows:

[0165] (51) First, determine the range of the outlet angle and wind speed of the nitrogen blowing duct. The outlet angle α is as follows: Figure 4 As shown in [30°, 90°] (when α is less than 30 degrees, the downward velocity component is too small and it is not easy to form a spiral), the wind speed is related to the performance of the air source. Different air sources can provide different maximum speeds. The range of wind speed is recorded as [1,v max ](Unit: L / min. A speed less than 1L / min cannot drive the liquid surface to rotate). max It is related to the pipeline pressure of the nitrogen blow-out duct. For example, the pipeline pressure of the nitrogen blow-out duct used in the laboratory allows v max It is 10L / min.

[0166] (52) The height from the bottom of the centrifuge tube to the liquid surface is recorded as h (mm). h is the height of the liquid surface.

[0167] (53) The liquid level is divided into several height intervals at intervals of a set height (e.g., 5 mm), which are denoted as H1, H2, ..., Hn. For example, [0-5] is denoted as H1, [5-10] is denoted as H2, and so on.

[0168] See also Figure 5 , Figure 5Schematic diagram of dividing the liquid level into several height intervals provided in the embodiment of the present application. Figure 5 As shown, the first height interval can be any one of H1 and H2, and the second height interval can be any one of H3-Hn. The sequence number corresponding to the height interval H1 is 1, the sequence number corresponding to the height interval H2 is 2, the sequence number corresponding to the height interval H3 is 3, ... The sequence number corresponding to the height interval Hn is n.

[0169] (54) Record the outlet angle α and wind speed v of Hm, and retain the first ten sets of data from high to low according to the evaporation efficiency to obtain the historical nitrogen blowing parameter set corresponding to Hm; its data format can be a dictionary: Hm:{LV1:(α,v),LV2:(α,v),.....,LV10:(α,v)}. The historical nitrogen blowing parameter set corresponding to Hm includes LV1:(α,v), LV2:(α,v),...,LV10:(α,v).

[0170] Hm is any one of the above-mentioned H1-Hn.

[0171] (55) Take a photo every 30 seconds with a cycle of 30 seconds, determine the liquid level h based on the photographed image (see step 101 above for details), and adapt the wind speed and wind angle based on the current liquid level.

[0172] See also Figure 6 , Figure 6 1 is a flow chart of setting the wind speed and wind angle according to the current liquid level provided by the embodiment of the present application. Figure 6 As shown, the process may include the following steps: determining the liquid level h; matching the height interval Hm corresponding to h; if Hm is one of H1 and H2, keeping the wind speed unchanged and adjusting the α cycle sweep wind; if Hm is not one of H1 and H2, determining whether the number of parameters in the historical nitrogen blowing parameter set corresponding to Hm is ten, and if not ten, generating a set of nitrogen blowing parameters α and v by a random method, and resetting the nitrogen blowing parameters α and v; if ten, selecting the historical nitrogen blowing parameters α and v with the highest evaporation efficiency in the historical nitrogen blowing parameter set corresponding to Hm with an 80% probability, and generating a set of nitrogen blowing parameters α and v by a random method with a 20% probability, and resetting the nitrogen blowing parameters α and v.

[0173] (56) Experimental data show that when the liquid level is between H1 and H2, the spiral airflow is difficult to form or even cannot be formed due to the smaller inner diameter of the centrifuge tube. At this time, the use of a sweeping strategy can make the evaporation efficiency higher, allowing the nitrogen outlet duct to circulate and sweep from 30 degrees to 90 degrees.

[0174] (57) The random method is divided into two parts. The air outlet angle α is directly randomly generated in the range of [30°, 90°]. The wind speed v is correlated with the liquid level. The farther the air outlet is from the liquid level, the greater the required wind speed. The farther the air outlet is from the liquid level, the greater the probability of randomly reaching a high wind speed. Wind speed v = P*v max (where v is the wind speed of the nitrogen blowing parameter, v max is the wind speed upper limit of the nitrogen blowing parameter, P is the random probability), R is a random number between 0 and 1, and n is the serial number corresponding to the height interval to which the liquid level belongs. The smaller the serial number, the farther the liquid level is from the nitrogen outlet, and the greater the probability of generating a higher wind speed.

[0175] For example, the probability distribution of serial numbers 3, 5, 10, 15, and 20 can be found in Figure 7a , Figure 7b , Figure 7c , Figure 7d and Figure 7e The horizontal axis is the probability value, and the vertical axis is the frequency of occurrence. The figure shows the probability distribution diagram generated by random 20,000 times. Figures 7a to 7e It can be seen that the smaller the serial number, the easier it is to randomly obtain a value close to 1, and the larger the serial number, the closer the probability value is to a uniform distribution.

[0176] (58) In the generation of wind speed and angle, the strategy of probability distribution is not completely followed. In order to strike a balance between the actual evaporation efficiency and the exploration of the best parameters, under the initial conditions, there is a first probability (for example, 80% probability) that the nitrogen blowing parameters with the highest historical evaporation efficiency will be adopted, and the second probability (for example, 20% probability) will explore possible better nitrogen blowing parameters. In addition, both the first probability and the second probability are configurable parameters. As the business volume of the system increases, the second probability can be gradually reduced or even set to zero.

[0177] After executing step 101 , the detection device may calculate the solution volume of the solution sample in the image based on the liquid level.

[0178] Optionally, the detection device calculates the solution volume of the solution sample in the image based on the liquid level, which may include the following steps:

[0179] The detection device determines the volume of the solution corresponding to the liquid level height based on the functional relationship between the height and the volume, and the functional relationship between the height and the volume can be obtained by fitting.

[0180] In the embodiment of the present application, the functional relationship between height and volume is obtained by fitting multiple sets of height and volume data. The liquid level height is input into the functional relationship between height and volume to obtain the solution volume corresponding to the liquid level height.

[0181] Optionally, before the detection device determines the volume of the solution corresponding to the liquid level height based on the functional relationship between the height and the volume, the following steps may also be performed:

[0182] (61) acquiring images of the container to be inspected when a plurality of different specified volumes are respectively injected therein, identifying the liquid level in each image, and obtaining a plurality of different liquid level heights;

[0183] (62) A functional relationship between height and volume is obtained by fitting the multiple different specified volumes and the multiple different liquid level heights.

[0184] Among them, step (61) and step (62) are the fitting processes of the functional relationship between height and volume.

[0185] In the embodiment of the present application, the output of the above deep learning model is expressed in pixel units. During the actual nitrogen blowing process, if the solution volume data corresponding to the liquid surface position at this time is needed, the camera can be calibrated to establish a functional relationship between height and volume V = F (pix). Wherein, pix is ​​the pixel unit of the model output, and V is the solution volume.

[0186] Take the centrifuge tube as an example. The camera calibration process is as follows:

[0187] 1. Arrange multiple (e.g. 8) empty centrifuge tubes on the nitrogen blowing equipment at one time;

[0188] 2. Use a pipette to add the specified volume of solution Vi into the centrifuge tube in sequence;

[0189] 3. Take photos with the camera after each addition of liquid;

[0190] 4. Input the photo into the deep learning model to get the pixel unit value Pi;

[0191] 5. Take the Pi data set as the independent variable and the Vi data set as the dependent variable, perform multiple multinomial data fitting, and obtain the functional relationship Vm=F(Pm).

[0192] Among them, multiple multi-item data fitting can be determined according to the shape of the centrifuge tube. For example, if the bottom of the centrifuge tube is conical, the volume is approximately the cone volume formula, 3V=πR 2 *H, wherein the height H and the radius R are in a linear relationship, V is a cubic function of H, and the multiple polynomial data fitting can be a cubic polynomial data fitting. It should be noted that different fitting models can be used for different types of containers.

[0193] See also Figure 8 , Figure 8 Schematic diagram of a multi-channel fully automatic nitrogen blowing method provided in the embodiment of the present application. Figure 8As shown, the method may include the following steps.

[0194] 801, moving the centrifuge tube into the hole of the temperature-controlled metal bath module;

[0195] The nitrogen blowing equipment may include a temperature-controlled metal bath module. The temperature-controlled metal bath module can control the temperature of the container to be tested placed therein, which is conducive to the nitrogen blowing. For example, the temperature of the container to be tested can be controlled to be stable at 40 degrees Celsius (℃). Multiple holes can be set on the temperature-controlled metal bath module, each hole can be placed in a centrifuge tube, and each centrifuge tube corresponds to a detection channel.

[0196] 802, specifying detection channel i, setting the near-dry volume discrimination standard dst_V of the detection channel i, and the corresponding sample name;

[0197] Multiple holes can be set on the temperature-controlled metal bath module. Each hole of the temperature-controlled metal bath module can be placed in a container to be tested. One container to be tested corresponds to one detection channel. The camera can take pictures of at least two containers to be tested at a time, so that it can automatically identify whether the solution samples in multiple containers to be tested meet the near-dry standard at one time, further improving the efficiency of nitrogen blow detection. For example, 8 containers to be tested can be placed in the temperature-controlled metal bath module, and each container to be tested corresponds to a nitrogen blow outlet duct. Two cameras can be used, and each camera can take images containing 4 containers to be tested (for example, camera 1 takes images containing containers 1 to 4 to be tested, and camera 2 takes images containing containers 5 to 8 to be tested).

[0198] 803, setting the camera shooting cycle;

[0199] 804, adaptively determining the camera's photographing parameters, the backlight brightness value, and the camera exposure time according to the color depth of the sample;

[0200] 805, the camera takes pictures according to the shooting cycle;

[0201] 806, identifying the liquid level h; after executing step 806, steps 807 and 808 may be executed;

[0202] 807, calculating the current solution volume Vi based on the liquid level h;

[0203] 808, determining nitrogen blowing parameters α, v according to the liquid level h;

[0204] 809, adjusting the flow valve of the motor and the nitrogen blowing outlet pipe according to the nitrogen blowing parameters α and v; after executing step 809, step 805 may be executed;

[0205] 810, determine whether Vi is less than or equal to dst_V; if so, execute step 811; if not, execute step 805;

[0206] 811, nitrogen blowing of return detection channel i is completed;

[0207] 812, stop nitrogen blowing of detection channel i, and notify to remove the centrifuge tube of detection channel i;

[0208] 813, determine whether all channels have completed nitrogen blowing; if so, execute step 814; if not, execute step 805;

[0209] 814, end.

[0210] Figure 8 The specific implementation of the steps can be found in the above Figures 1 to 6 The embodiments in the description will not be repeated here.

[0211] The embodiment of the present application provides a multi-channel fully automatic nitrogen blowing method, which can achieve a high level of near-dryness discrimination accuracy based on a deep learning method (for example, the near-dryness accuracy can reach 20ul). One camera can monitor four centrifuge tubes at the same time, can monitor four channels at the same time, and can dynamically adapt the wind speed and blowing angle, thereby improving the nitrogen blowing efficiency; it can improve the coverage of automatic nitrogen blowing, can adapt to the backlight intensity and camera exposure parameters, and can cover more types of samples.

[0212] The above mainly introduces the scheme of the embodiment of the present application from the perspective of the execution process on the method side. It is understandable that, in order to realize the above functions, the detection device includes a hardware structure and / or software module corresponding to the execution of each function. Those skilled in the art should easily realize that, in combination with the units and algorithm steps of each example described in the embodiment provided herein, the present application can be implemented in the form of hardware or a combination of hardware and computer software. Whether a function is executed in the form of hardware or computer software driving hardware depends on the specific application and design constraints of the technical solution. Professional and technical personnel can use different methods to implement the described functions for each specific application, but such implementation should not be considered to be beyond the scope of the present application.

[0213] The embodiment of the present application can divide the functional units of the detection device according to the above method example. For example, each functional unit can be divided according to each function, or two or more functions can be integrated into one processing unit. The above integrated unit can be implemented in the form of hardware or in the form of software functional units. It should be noted that the division of units in the embodiment of the present application is schematic and is only a logical function division. There may be other division methods in actual implementation.

[0214] See also Fig. 9 , Fig. 9is a structural schematic diagram of a nitrogen blowing parameter adjustment device provided in an embodiment of the present application, such as Fig. 9 As shown, the nitrogen blowing parameter adjustment device 900 includes:

[0215] An acquisition unit 901 is used to acquire the liquid level height of the solution sample when a solution sample is contained in a detected container and the detected container is nitrogen-blown using current nitrogen-blowing parameters;

[0216] A determination unit 902, configured to determine a target nitrogen blowing parameter based on the liquid level;

[0217] The adjusting unit 903 is used to adjust the current nitrogen blowing parameter to the target nitrogen blowing parameter when the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

[0218] Optionally, the adjusting unit 903 is further configured to maintain the current nitrogen blowing parameter unchanged when the target nitrogen blowing parameter is the same as the current nitrogen blowing parameter.

[0219] Optionally, the determination unit 902 determines the target nitrogen blowing parameters based on the liquid level height, including: determining a height interval corresponding to the liquid level height according to the liquid level height; wherein the detected container is pre-divided into at least two height intervals; and determining the target nitrogen blowing parameters according to the height interval corresponding to the liquid level height.

[0220] Optionally, the nitrogen blowing parameters include an air outlet angle and a wind speed, and the determination unit 902 determines the target nitrogen blowing parameters according to the height interval corresponding to the liquid level, including:

[0221] When the height interval of the liquid level is the first height interval, determining a first target nitrogen blowing parameter; wherein the wind speed of the first target nitrogen blowing parameter is the same as the wind speed of the current nitrogen blowing parameter, and the wind outlet angle of the first target nitrogen blowing parameter changes periodically within a set angle range;

[0222] When the height interval corresponding to the liquid level height is the second height interval, a second target nitrogen blowing parameter is determined; wherein the second target nitrogen blowing parameter is a historical nitrogen blowing parameter corresponding to the second height interval, or the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method; and the upper limit value of the first height interval is less than or equal to the lower limit value of the second height interval.

[0223] Optionally, the setting angle range is 30° to 90°;

[0224] The inner diameter of the inspected container in the second height interval is greater than the inner diameter of the inspected container in the first height interval.

[0225] Optionally, within the first height interval, the inner diameter of the detected container is positively correlated with the liquid level height.

[0226] Optionally, when the number of parameters in the historical nitrogen blowing parameter set is less than a first threshold, the historical nitrogen blowing parameter set corresponding to the second height interval includes all nitrogen blowing parameters historically determined for the liquid level within the second height interval;

[0227] When the number of parameters in the historical nitrogen blowing parameter set is greater than or equal to the first threshold, the historical nitrogen blowing parameter set corresponding to the second height interval includes N historical nitrogen blowing parameter sets ranked top N in terms of evaporation efficiency historically determined at the liquid level within the second height interval, where N is equal to the first threshold.

[0228] Optionally, the determining unit 902 determines the second target nitrogen blowing parameter, including:

[0229] Determine a set of historical nitrogen blowing parameters corresponding to the second height interval;

[0230] According to a first probability, the second target nitrogen blowing parameter is selected as one or any one of the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set, and according to a second probability, the second target nitrogen blowing parameter is selected as a nitrogen blowing parameter generated by a random method; the sum of the first probability and the second probability is equal to 1.

[0231] Optionally, the determining unit 902 selects the second target nitrogen blowing parameter as one or any one of the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set according to the first probability, and selects the second target nitrogen blowing parameter as a nitrogen blowing parameter generated by a random method according to the second probability, including:

[0232] When the number of parameters in the historical nitrogen blowing parameter set is greater than or equal to a first threshold, the second target nitrogen blowing parameter is selected according to a first probability as the historical nitrogen blowing parameter with the highest evaporation efficiency in the historical nitrogen blowing parameter set, and the second target nitrogen blowing parameter is selected according to a second probability as the nitrogen blowing parameter generated by a random method; the first probability is greater than the second probability.

[0233] Optionally, the determining unit 902 is further configured to determine, when the number of parameters in the historical nitrogen blowing parameter set is less than the first threshold, that the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method.

[0234] Optionally, the nitrogen blowing parameters generated by the random method include:

[0235] The outlet angle of the nitrogen blowing parameter is randomly generated within the set angle range;

[0236] The wind speed of the nitrogen blowing parameter is generated according to the following formula:

[0237] v=P*v max ;

[0238] Wherein, v is the wind speed of the nitrogen blowing parameter, v max is the upper limit of wind speed of nitrogen blowing parameters, and P is the random probability.

[0239] Optional,

[0240] Wherein, P is a random probability, R is a random number between 0 and 1, and n is a serial number corresponding to the second height interval; n is negatively correlated with the distance from the second height interval to the nitrogen outlet.

[0241] Optionally, the acquiring unit 901 acquires the liquid level of the solution sample, including: acquiring an image including the detected container captured according to a set capturing cycle, and identifying the liquid level of the solution sample in the image.

[0242] Optionally, the acquisition unit 901 identifies the liquid level height of the solution sample in the image, including: inputting the image into a deep learning model to obtain the pixel unit value of the liquid level position of the solution sample, and determining the liquid level height corresponding to the pixel unit value of the liquid level position according to the corresponding relationship between the pixel unit value and the height.

[0243] Optionally, the nitrogen blowing parameter adjustment device 900 further includes a training unit 904;

[0244] The training unit 904 is used to periodically acquire an image containing the container to be inspected when the container to be inspected contains a solution sample and the container to be inspected is nitrogen-blown; when the liquid level position of the image is manually marked, pre-process the manually marked image to obtain a plurality of sample images corresponding to the image; use the plurality of sample images and the corresponding liquid level positions as training samples, and use the training samples to perform model training to obtain the deep learning model.

[0245] Optionally, the determining unit 902 determines a target nitrogen blowing parameter based on the liquid level, including:

[0246] The type of the solution sample is obtained; and a target nitrogen blowing parameter is determined based on the type of the solution sample and the liquid level.

[0247] Optionally, the determining unit 902 determines the target nitrogen blowing parameter based on the type of the solution sample and the liquid level, including:

[0248] In a case where there are nitrogen blowing parameters corresponding to the type of the solution sample, determining a target nitrogen blowing parameter corresponding to the liquid level height from the nitrogen blowing parameters corresponding to the type of the solution sample;

[0249] When there is no nitrogen blowing parameter corresponding to the type of the solution sample, and there is a nitrogen blowing parameter corresponding to the first type, determine the target nitrogen blowing parameter corresponding to the liquid level height from the nitrogen blowing parameters corresponding to the first type; the first type and the type of the solution sample belong to the same large category set, or the similarity between the first type and the type of the solution sample reaches a second threshold.

[0250] The acquisition unit 901 may be a communication module in the detection device, and the determination unit 902, the adjustment unit 903, and the training unit 904 may be processors in the detection device.

[0251] Fig. 9 The specific implementation of the nitrogen blowing parameter adjustment device 900 shown can be found in Figure 1 and Figure 8 The method embodiment shown will not be described in detail here.

[0252] In the embodiment of the present application, the liquid level of the solution sample in the image containing the detected container can be identified, and the nitrogen blowing parameters can be adjusted according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency.

[0253] See also Fig.10 , Fig.10 is a schematic diagram of the structure of a detection device provided in an embodiment of the present application, such as Fig.10 As shown, the detection device 1000 includes a processor 1001 and a memory 1002, and the processor 1001 and the memory 1002 can be connected to each other via a communication bus 1003. The communication bus 1003 can be a peripheral component interconnect standard (PCI) bus or an extended industry standard architecture (EISA) bus. The communication bus 1003 can be divided into an address bus, a data bus, a control bus, etc. For ease of representation, Fig.10 The memory 1002 is used to store computer programs. The computer programs include program instructions. The processor 1001 is configured to call the program instructions. The program includes instructions for executing Figure 1 and Figure 8 Some or all of the steps in the method shown.

[0254] The memory 1002 may be a read-only memory (ROM) or other types of static storage devices that can store static information and instructions, a random access memory (RAM) or other types of dynamic storage devices that can store information and instructions, or an electrically erasable programmable read-only memory (EEPROM), a compact disc read-only memory (CD-ROM) or other optical disc storage, optical disc storage (including compressed optical disc, laser disc, optical disc, digital versatile disc, Blu-ray disc, etc.), a magnetic disk storage medium or other magnetic storage device, or any other medium that can be used to carry or store the desired program code in the form of instructions or data structures and can be accessed by a computer, but is not limited thereto. The memory may exist independently and be connected to the processor via a bus. The memory may also be integrated with the processor.

[0255] The detection device 1000 may further include a communication module 1004. The communication module 1004 may communicate with the camera.

[0256] In the embodiment of the present application, the liquid level of the solution sample in the image containing the detected container can be identified, and the nitrogen blowing parameters can be adjusted according to the liquid level to improve the evaporation efficiency, thereby improving the nitrogen blowing efficiency.

[0257] An embodiment of the present application also provides a computer-readable storage medium, wherein the computer-readable storage medium stores a computer program for electronic data exchange, and the computer program enables a computer to execute part or all of the steps of any nitrogen blowing parameter adjustment method recorded in the above method embodiments.

[0258] It should be noted that, for the aforementioned method embodiments, for the sake of simplicity, they are all expressed as a series of action combinations, but those skilled in the art should be aware that the present application is not limited by the described order of actions, because according to the present application, certain steps can be performed in other orders or simultaneously. Secondly, those skilled in the art should also be aware that the embodiments described in the specification are all preferred embodiments, and the actions and modules involved are not necessarily required by the present application.

[0259] In the above embodiments, the description of each embodiment has its own emphasis. For parts that are not described in detail in a certain embodiment, reference can be made to the relevant descriptions of other embodiments.

[0260] In the several embodiments provided in the present application, it should be understood that the disclosed device can be implemented in other ways. For example, the device embodiments described above are only schematic, such as the division of the units, which is only a logical function division. There may be other division methods in actual implementation, such as multiple units or components can be combined or integrated into another system, or some features can be ignored or not executed. Another point is that the mutual coupling or direct coupling or communication connection shown or discussed can be through some interfaces, and the indirect coupling or communication connection of the device or unit can be electrical or other forms.

[0261] The units described as separate components may or may not be physically separated, and the components shown as units may or may not be physical units, that is, they may be located in one place or distributed on multiple network units. Some or all of the units may be selected according to actual needs to achieve the purpose of the solution of this embodiment.

[0262] In addition, the functional units in the various embodiments of the application may be integrated into one processing unit, or each unit may exist physically separately, or two or more units may be integrated into one unit. The above-mentioned integrated units may be implemented in the form of hardware or in the form of software program modules.

[0263] If the integrated unit is implemented in the form of a software program module and sold or used as an independent product, it can be stored in a computer-readable memory. Based on this understanding, the technical solution of the present application is essentially or the part that contributes to the prior art or all or part of the technical solution can be embodied in the form of a software product, and the computer software product is stored in a memory, including a number of instructions to enable a computer device (which can be a personal computer, a detection device or a network device, etc.) to perform all or part of the steps of the method described in each embodiment of the present application. The aforementioned memory includes: U disk, read-only memory (ROM), random access memory (RAM), mobile hard disk, disk or optical disk and other media that can store program codes.

[0264] A person of ordinary skill in the art can understand that all or part of the steps in the various methods of the above embodiments can be completed by instructing related hardware through a program, and the program can be stored in a computer-readable memory, which can include: a flash drive, a read-only memory, a random access memory, a magnetic disk or an optical disk, etc.

[0265] The embodiments of the present application are introduced in detail above. Specific examples are used in this article to illustrate the principles and implementation methods of the present application. The description of the above embodiments is only used to help understand the method and core idea of ​​the present application. At the same time, for general technical personnel in this field, according to the idea of ​​the present application, there will be changes in the specific implementation method and application scope. In summary, the content of this specification should not be understood as a limitation on the present application.

Claims

1. A method for adjusting nitrogen blowing parameters, characterized in that: include: When a solution sample is contained in a container to be tested and the container to be tested is nitrogen-blown using current nitrogen-blowing parameters, a liquid level of the solution sample is obtained, and a target nitrogen-blowing parameter is determined based on the liquid level; When the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, the current nitrogen blowing parameter is adjusted to the target nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

2. The method according to claim 1, characterized in that The method further comprises: When the target nitrogen blowing parameter is the same as the current nitrogen blowing parameter, the current nitrogen blowing parameter is maintained unchanged.

3. The method according to claim 1, characterized in that The step of determining a target nitrogen blowing parameter based on the liquid level comprises: Determining a height interval corresponding to the liquid level height according to the liquid level height; wherein the detected container is pre-divided into at least two height intervals; The target nitrogen blowing parameter is determined according to the height interval corresponding to the liquid level height.

4. The method according to claim 3, characterized in that The nitrogen blowing parameters include an outlet angle and a wind speed, and the target nitrogen blowing parameters are determined according to the height interval corresponding to the liquid level, including: When the height interval corresponding to the liquid level height is the first height interval, determining a first target nitrogen blowing parameter; wherein the wind speed of the first target nitrogen blowing parameter is the same as the wind speed of the current nitrogen blowing parameter, and the wind outlet angle of the first target nitrogen blowing parameter changes periodically within a set angle range; When the height interval corresponding to the liquid level height is the second height interval, a second target nitrogen blowing parameter is determined; wherein the second target nitrogen blowing parameter is a historical nitrogen blowing parameter corresponding to the second height interval, or the second target nitrogen blowing parameter is a nitrogen blowing parameter generated by a random method; and the upper limit value of the first height interval is less than or equal to the lower limit value of the second height interval.

5. The method according to claim 4, characterized in that The setting angle range is 30° to 90°; The inner diameter of the inspected container in the second height interval is greater than the inner diameter of the inspected container in the first height interval.

6. The method according to claim 4, characterized in that Determining the second target nitrogen blowing parameter includes: Determine a set of historical nitrogen blowing parameters corresponding to the second height interval; According to a first probability, the second target nitrogen blowing parameter is selected as one or any one of the historical nitrogen blowing parameters in the historical nitrogen blowing parameter set; according to a second probability, the second target nitrogen blowing parameter is selected as a nitrogen blowing parameter generated by a random method; the sum of the first probability and the second probability is equal to 1.

7. The method according to claim 6, characterized in that The step of selecting the second target nitrogen blowing parameter as one or any one of the historical nitrogen blowing parameter sets according to the first probability, and selecting the second target nitrogen blowing parameter as a nitrogen blowing parameter generated by a random method according to the second probability, comprises: When the number of parameters in the historical nitrogen blowing parameter set is greater than or equal to a first threshold, the second target nitrogen blowing parameter is selected as the historical nitrogen blowing parameter with the highest evaporation efficiency in the historical nitrogen blowing parameter set according to a first probability, and the second target nitrogen blowing parameter is selected as the nitrogen blowing parameter generated by a random method according to a second probability; the first probability is greater than the second probability.

8. The method according to claim 7, characterized in that The method further comprises: When the number of parameters in the historical nitrogen blowing parameter set is less than the first threshold, the second target nitrogen blowing parameter is determined to be a nitrogen blowing parameter generated by using the random method.

9. The method according to claim 4, characterized in that The nitrogen blowing parameters generated by the random method include: The outlet angle of the nitrogen blowing parameter is randomly generated within the set angle range; The wind speed of the nitrogen blowing parameter is generated according to the following formula: v=P*v max ; Wherein, v is the wind speed of the nitrogen blowing parameter, v max is the upper limit of wind speed of nitrogen blowing parameters, and P is the random probability.

10. The method according to claim 9, characterized in that Wherein, P is a random probability, R is a random number between 0 and 1, and n is a serial number corresponding to the second height interval; n is negatively correlated with the distance from the second height interval to the nitrogen outlet.

11. The method according to any one of claims 1 to 10, characterized in that: The step of obtaining the liquid level of the solution sample comprises: An image including the detected container captured according to a set capturing cycle is acquired, and a liquid level of the solution sample in the image is identified.

12. The method according to claim 11, characterized in that The step of identifying the liquid level of the solution sample in the image comprises: The image is input into a deep learning model to obtain a pixel unit value of the liquid level position of the solution sample, and the liquid level height corresponding to the pixel unit value of the liquid level position is determined according to a corresponding relationship between the pixel unit value and the height.

13. The method according to claim 12, characterized in that Before inputting the image into the deep learning model, the method further includes: When a solution sample is contained in a container to be inspected and nitrogen is blown to the container to be inspected, periodically acquiring an image containing the container to be inspected; In the case where the liquid surface position of the image is manually marked, preprocessing the manually marked image to obtain a plurality of sample images corresponding to the image; The multiple sample images and the corresponding liquid surface positions are used as training samples, and the training samples are used to perform model training to obtain the deep learning model.

14. The method according to any one of claims 1 to 10, characterized in that: The step of determining a target nitrogen blowing parameter based on the liquid level comprises: obtaining the type of the solution sample; The target nitrogen purge parameters are determined based on the type of the solution sample and the liquid level.

15. The method according to claim 14, characterized in that The step of determining a target nitrogen blowing parameter based on the type of the solution sample and the liquid level height includes: In a case where there are nitrogen blowing parameters corresponding to the type of the solution sample, determining a target nitrogen blowing parameter corresponding to the liquid level height from the nitrogen blowing parameters corresponding to the type of the solution sample; When there is no nitrogen blowing parameter corresponding to the type of the solution sample, and there is a nitrogen blowing parameter corresponding to the first type, determine the target nitrogen blowing parameter corresponding to the liquid level height from the nitrogen blowing parameters corresponding to the first type; the first type and the type of the solution sample belong to the same large category set, or the similarity between the first type and the type of the solution sample reaches a second threshold.

16. A nitrogen blowing parameter adjustment device, characterized in that: include: an acquisition unit, for acquiring a liquid level height of the solution sample when a solution sample is contained in a detected container and the detected container is nitrogen-blown using current nitrogen-blowing parameters; A determination unit, configured to determine a target nitrogen blowing parameter based on the liquid level; The adjustment unit is used to adjust the current nitrogen blowing parameter to the target nitrogen blowing parameter when the target nitrogen blowing parameter is different from the current nitrogen blowing parameter, and the evaporation efficiency of the target nitrogen blowing parameter is greater than or equal to the evaporation efficiency of the current nitrogen blowing parameter.

17. A detection device, characterized in that: The method comprises a processor and a memory, wherein the memory is used to store a computer program, the computer program comprises program instructions, and the processor is configured to call the program instructions to execute the method according to any one of claims 1 to 15.

18. A computer-readable storage medium, characterized in that: The computer-readable storage medium stores a computer program, wherein the computer program includes program instructions, and when the program instructions are executed by a processor, the processor is caused to perform the method according to any one of claims 1 to 15.

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