Decoction for treating lumbar disc herniation and preparation method thereof

Abstract

The invention discloses a decoction for treating lumbar disc herniation and a preparation method thereof, and belongs to the technical field of traditional Chinese medicines. The invention relates to a decoction for treating lumbar disc herniation. The decoction is prepared from the following raw material medicines in parts by mass: 35-45 parts of cornu bubali slices, 8-10 parts of angelica sinensis, 8-10 parts of radix achyranthis bidentatae, 13-15 parts of parasitic loranthus, 12-15 parts of dipsacus root, 8-10 parts of cassia twig, 11-13 parts of rhizoma drynariae, 24-28 parts of astragalus membranaceus, 20-25 parts of black beans, 15-20 parts of notopterygium root, 15-20 parts of rhizoma corydalis, 3-8 parts of zaocys dhumnade and 8-10 parts of pawpaw. The pure traditional Chinese medicine for promoting blood circulation to remove blood stasis, tonifying kidney and strengthening bones and clearing and activating the channels and collaterals is obtained by adopting specific raw material medicine varieties and proportions, pathological products of blood stasis and edema which are caused by lesion and oppress nerves are eliminated, and the lumbar disc herniation is effectively and thoroughly cured.

Description

Technical Field

[0001] The invention relates to the technical field of traditional Chinese medicines, and more particularly to a decoction for treating lumbar disc herniation and a preparation method thereof. Background Art

[0002] Lumbar disc herniation is mainly caused by the degenerative changes of the various parts of the lumbar disc (nucleus pulposus, annulus fibrosus and cartilage plate), especially the nucleus pulposus, to varying degrees. Under the influence of external factors, the annulus fibrosus of the disc ruptures, and the nucleus pulposus tissue protrudes (or falls out) from the ruptured part to the back or inside the spinal canal, causing the adjacent spinal nerve roots to be stimulated or compressed, resulting in a series of clinical symptoms such as low back pain, numbness and pain in one or both lower limbs. The highest incidence of lumbar disc herniation is in L4-5 and L5-S1, accounting for about 95%.

[0003] At present, the main surgical treatments for lumbar disc herniation are lamina, articular process and disc resection or disc protease injection, which have a narrow scope of application and poor prognosis, so most patients use non-surgical treatments to alleviate the condition. In addition to bed rest and exercise, Western medicine generally uses drugs such as chondroitin sulfate, while Chinese medicine generally uses auxiliary treatments such as internal and external Chinese medicines for promoting blood circulation and removing blood stasis, strengthening tendons and bones, and replenishing the middle qi or Shujin Jianyao pills. Due to the long course of lumbar disc herniation and the slow onset of treatment, adverse reactions such as allergies are common when Chinese medicine ingredients are used externally.

[0004] Therefore, how to develop a decoction for treating lumbar disc herniation and a preparation method thereof is a technical problem that needs to be solved urgently by those skilled in the art. Summary of the invention

[0005] In view of this, the present invention provides a decoction for treating lumbar disc herniation and a preparation method thereof.

[0006] In order to achieve the above object, the present invention adopts the following technical solution:

[0007] A decoction for treating lumbar disc herniation, comprising the following raw materials in parts by weight:

[0008] 35-45 parts of buffalo horn slices, 8-10 parts of angelica sinensis, 8-10 parts of achyranthes bidentata, 13-15 parts of parasitic herb, 12-15 parts of chuanxiong, 8-10 parts of cassia twig, 11-13 parts of drynariae, 24-28 parts of astragalus, 20-25 parts of black beans, 15-20 parts of notopterygium, 15-20 parts of corydalis, 3-8 parts of serpentine, and 8-10 parts of papaya.

[0009] Buffalo Horn Tablets: bitter, salty, cold in nature. Enters the Heart and Liver Meridians. Clears away heat, detoxifies, cools blood, and calms convulsions. Treats fever headaches, high fever and coma, rash and rashes, vomiting blood, epistaxis, jaundice caused by blood stasis, convulsions in children and sore throat, and mouth and tongue ulcers.

[0010] Angelica: warm in nature, sweet and pungent in taste, enters the liver, heart and spleen meridians. It nourishes blood and activates blood circulation, regulates menstruation and relieves pain, moistens the intestines and promotes bowel movements. It is used for blood deficiency and sallow complexion, dizziness and palpitations, irregular menstruation, amenorrhea and dysmenorrhea, abdominal pain due to deficiency and cold, constipation due to dry intestines, rheumatic arthralgia, injuries from falls, carbuncles and ulcers.

[0011] Achyranthes bidentata: bitter; sour; neutral in nature. Enters the liver and kidney meridians. Nourishes the liver and kidneys; strengthens tendons and bones; activates blood circulation and dredges the menstruation; draws fire (blood) downward; promotes diuresis and relieves stranguria. Treats soreness of waist and knees; paralysis of lower limbs; blood stasis and amenorrhea; dysmenorrhea; abdominal pain due to blood stasis after childbirth; abdominal masses; retained placenta; hot stranguria; hematuria; traumatic injury; carbuncle and malignant ulcer; sore throat.

[0012] Mulberry parasite: bitter and sweet, neutral, enters the liver and kidney meridians. Nourishes the liver and kidneys, strengthens the tendons and bones, removes rheumatism, dredges the meridians, replenishes blood, and stabilizes the fetus. Treats soreness of the waist and knees, weakness of the tendons and bones, hemiplegia, beriberi, wind-cold-dampness arthralgia, bleeding and metrorrhagia, and postpartum milk retention. Treats chronic cough, tongue-stretching and dizziness.

[0013] Chuanduan: nourishes the liver and kidneys, strengthens the tendons and bones, and regulates blood vessels. Treats back pain, weak feet and knees, miscarriage, metrorrhagia, leukorrhea, spermatorrhea, traumatic injuries, wounds, hemorrhoidal fistula, carbuncle, and swelling.

[0014] Cinnamon twig: pungent, sweet, warm in nature, can induce sweating, relieve exterior symptoms, dispel cold and relieve pain, promote yang and transform qi. It is used for colds, cold blood stagnation, various pain symptoms, phlegm, water retention, and palpitations.

[0015] Drynaria: bitter, warms the kidney and strengthens bones, heals injuries and relieves pain. Used for kidney deficiency and low back pain, tinnitus and deafness, loose teeth, falls, sprains, tendon fractures and injuries; external treatment of alopecia areata and vitiligo.

[0016] Astragalus: sweet in taste, slightly warm in nature; enters the spleen and lung meridians. It replenishes qi and strengthens the exterior, removes toxins and discharges pus, promotes urination, and promotes tissue regeneration. It is used for qi deficiency, fatigue, chronic diarrhea, and rectal prolapse.

[0017] Black beans: sweet in taste, neutral in nature, and enter the spleen and kidney meridians. They can improve the eyesight, nourish blood and dispel wind, promote diuresis, and detoxify. They are suitable for the treatment of yin deficiency, thirst, dizziness, physical weakness and sweating, kidney deficiency and low back pain, edema and oliguria, pain and cramps, numbness of hands and feet, drug and food poisoning, etc.

[0018] Qianghuo: pungent, bitter, warm in nature, enters the bladder and kidney meridians, dispels superficial cold, dispels rheumatism, benefits joints, and relieves pain. It is used to treat exogenous wind-cold, headache without sweating, cold-dampness arthralgia, edema, and sores.

[0019] Yuanhu: It is pungent, bitter and warm in nature and mainly enters the liver and spleen meridians. Its main functions are to promote blood circulation, promote qi circulation and relieve pain. It is used to treat pain caused by qi and blood stasis.

[0020] Black-necked snake: sweet, neutral. Enters the lung, spleen, and liver meridians. Removes rheumatism, dredges the meridians, and stops spasms. Treats rheumatism, numbness of the skin, cramps of tendons and veins, paralysis of limbs, tetanus, leprosy, rubella, scabies, and tinea.

[0021] Papaya: It has the effects of relaxing muscles and tendons, harmonizing the stomach and removing dampness, and treating indigestion. Papaya is warm in nature, pungent and sour in taste, and is mainly used to treat rheumatism, beriberi edema, vomiting and diarrhea, food stagnation, stomach bloating and vomiting, and other diseases.

[0022] Beneficial effects of the present invention: Antelope horn is a precious Chinese medicinal material, but due to its rare source and being a national protected animal, its use is strictly restricted. Buffalo horn and antelope horn have certain similarities in efficacy. From the perspective of traditional Chinese medicine theory, both buffalo horn and antelope horn have the effects of clearing heat and calming the nerves, but the efficacy of buffalo horn is relatively weak, so it is necessary to increase the dosage of buffalo horn. The inventor has determined the optimal dosage range of buffalo horn slices in combination with cost and efficacy considerations.

[0023] The present invention adopts specific raw material drug types and proportions to obtain a pure Chinese medicine that can promote blood circulation and remove blood stasis, nourish the kidney and strengthen bones, and promote blood circulation and activate collaterals, thereby eliminating the pathological products of blood stasis and edema caused by nerve compression by lesions, and effectively and thoroughly cures lumbar disc herniation.

[0024] Furthermore, the decoction for treating lumbar disc herniation comprises the following raw materials in parts by weight:

[0025] 40 parts of buffalo horn slices, 9 parts of angelica sinensis, 9 parts of achyranthes bidentata, 14 parts of parasitic herb, 13 parts of chuanxiong, 9 parts of cassia twig, 12 parts of drynariae, 26 parts of astragalus, 23 parts of black beans, 18 parts of notopterygium, 17 parts of corydalis, 5 parts of serpentines, and 9 parts of papaya.

[0026] The present invention also provides a method for preparing a decoction for treating lumbar disc herniation, comprising the following steps:

[0027] (1) Weighing each raw material according to the decoction for treating lumbar disc herniation;

[0028] (2) Place the corydalis in a pot and fry over low heat until the surface is melted and bubbles appear. Spray rice vinegar on it and continue frying until the outer layer is bright and translucent. Remove from the pot and let cool.

[0029] (3) Put water buffalo horn slices, angelica, Achyranthes bidentata, mistletoe, Chuanduan, cinnamon twig, drynaria, astragalus, black bean, Notopterygium wilfordii, Corydalis yanhusuo, black-spotted snake and papaya into a decoction container and soak in water;

[0030] (4) After soaking, the raw medicinal materials are naturally boiled over high heat, then slowly simmered over low heat, and then the heat is turned off. The raw medicinal materials are cooled and taken orally.

[0031] Beneficial effects of the present invention: The present invention prepares the Rhizoma Corydalis with vinegar, which can enhance its blood circulation and qi activating effect and improve the analgesic effect. After the Rhizoma Corydalis is prepared with vinegar, its alkaloid components are easier to be decocted, so that it can treat various pain syndromes caused by qi stagnation and blood stasis. The preparation method of the decoction for treating lumbar disc herniation of the present invention is simple, easy to operate, and suitable for wide clinical application.

[0032] Furthermore, in step (2), the mass ratio of Corydalis yanhusuo and rice vinegar is 100:(7-10).

[0033] The beneficial effect of adopting the above further technical scheme is that the Rhizoma Corydalis and rice vinegar are prepared in a specific ratio, and the alkaloids therein are combined with acetic acid to form acetates that are easily soluble in water, which are easily dissolved during decocting, thereby improving the clinical efficacy.

[0034] Furthermore, in step (3), the mass ratio of water added to the raw material drug is (8-10):1, and the soaking time is 40-45 minutes.

[0035] The beneficial effect of adopting the above further technical solution is: soaking the raw material medicine in water makes the effective ingredients of the raw material medicine easier to dissolve during decoction.

[0036] Furthermore, in step (4), the time for slow frying over low heat is 20-25 minutes, and the mixture is taken orally after cooling to 37-40°C.

[0037] The beneficial effect of adopting the above further technical solution is: slow decocting over low heat for a specific time to ensure the dissolution of the active ingredients of the raw material medicine. DETAILED DESCRIPTION

[0038] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0039] Example 1

[0040] The preparation method of a decoction for treating lumbar disc herniation comprises the following steps:

[0041] (1) Weigh 40 g of water buffalo horn slices, 9 g of Chinese angelica, 9 g of Achyranthes bidentata, 14 g of Viscum album, 13 g of Rhizoma Chuanxiong, 9 g of Cinnamon twig, 12 g of Drynariae rhizome, 26 g of Astragalus, 23 g of black bean, 18 g of Notopterygium wilfordii, 17 g of Rhizoma Corydalis, 5 g of Snakehead snake, and 9 g of Papaya;

[0042] (2) Put the corydalis in a pot and stir-fry over low heat until the surface melts and bubbles appear, then spray with rice vinegar, the mass ratio of corydalis to rice vinegar being 100:8, continue stir-frying until the outer layer is bright and translucent, then take out and let cool;

[0043] (3) Put water buffalo horn slices, angelica, Achyranthes bidentata, mistletoe, Chuanduan, cinnamon twig, bone-drying herb, astragalus, black bean, Notopterygium wilfordii, Corydalis yanhusuo, snake snake and papaya into a decoction container and soak in water. The mass ratio of water to raw material is 9:1, and the soaking time is 42 min.

[0044] (4) The soaked raw materials are naturally boiled over high heat, and then slowly simmered over low heat for 22 minutes. The heat is turned off, and the raw materials are cooled to 38°C before oral administration.

[0045] Example 2

[0046] The preparation method of a decoction for treating lumbar disc herniation comprises the following steps:

[0047] (1) Weigh 35 g of water buffalo horn slices, 8 g of Chinese angelica, 8 g of Achyranthes bidentata, 13 g of Sarcandra viride, 12 g of Rhizoma Chuanxiong, 8 g of Cinnamomum cassia, 11 g of Drynariae rhizome, 24 g of Astragalus, 20 g of black bean, 15 g of Notopterygium incisum, 15 g of Rhizoma Corydalis, 3 g of Snakehead acanthus, and 8 g of Papaya;

[0048] (2) Put the corydalis in a pot and stir-fry over low heat until the surface melts and bubbles appear, then spray with rice vinegar, the mass ratio of corydalis to rice vinegar being 100:7, continue stir-frying until the outer layer is bright and translucent, then take out and let cool;

[0049] (3) Put water buffalo horn slices, angelica, Achyranthes bidentata, mistletoe, Chuanduan, cinnamon twig, bone-drying herb, astragalus, black bean, Notopterygium wilfordii, Corydalis yanhusuo, snake snake and papaya into a decoction container and soak in water, the mass ratio of water to raw material is 8:1, and the soaking time is 40 min;

[0050] (4) The soaked raw materials are naturally boiled over high heat, and then slowly simmered over low heat for 20 minutes. Turn off the heat, cool to 37°C, and then take orally.

[0051] Example 3

[0052] The preparation method of a decoction for treating lumbar disc herniation comprises the following steps:

[0053] (1) Weigh 45 g of buffalo horn slices, 10 g of angelica sinensis, 10 g of Achyranthes bidentata, 15 g of Viscum album, 15 g of Rhizoma Chuanxiong, 10 g of cinnamon twig, 13 g of Drynaria fortunei, 28 g of Astragalus membranaceus, 25 g of black bean, 20 g of Notopterygium incisum, 20 g of Rhizoma Corydalis, 8 g of Snakehead acanthus sinensis, and 10 g of papaya;

[0054] (2) Put the corydalis in a pot and stir-fry over low heat until the surface melts and bubbles appear, then spray with rice vinegar, the mass ratio of corydalis to rice vinegar being 100:10, continue stir-frying until the outer layer is bright and translucent, then take out and let cool;

[0055] (3) Put water buffalo horn slices, angelica, Achyranthes bidentata, mistletoe, Chuanduan, cinnamon twig, bone-drying herb, astragalus, black bean, Notopterygium wilfordii, Corydalis yanhusuo, snake snake and papaya into a decoction container and soak in water, the mass ratio of water to raw material is 10:1, and the soaking time is 45 min;

[0056] (4) The soaked raw materials are naturally boiled over high heat, and then slowly simmered over low heat for 25 minutes. The heat is turned off, and the raw materials are cooled to 40°C before oral administration.

[0057] 1. Clinical data:

[0058] There were 100 cases in total, aged 18-70 years old, 50 males and 50 females.

[0059] 2. Diagnostic criteria:

[0060] "Standards for Diagnosis and Efficacy of Traditional Chinese Medicine Diseases".

[0061] 3. Directions:

[0062] Take the decoction obtained in Example 1 of the present invention, and take 200 ml orally for adults each time, twice a day.

[0063] 4. Efficacy standards:

[0064] Significant effect: symptoms disappear;

[0065] Effective: symptoms are significantly relieved;

[0066] Ineffective: No significant improvement in symptoms.

[0067] 5. Treatment results:

[0068] After 3 months, among 100 patients who used the medicine of the present invention, 88 were markedly effective, 11 were effective, and 1 was ineffective, with a markedly effective rate of 88% and a total effective rate of 99%.

[0069] Typical Cases

[0070] 1. Wang Moumou, female, 36 years old, a teacher at Xingtai Medical College, visited the hospital in May 2006. The patient used to have hip pain due to frequent fatigue. Recently, she had severe pain in the left waist and legs due to catching a cold, and her movements were limited. After CT diagnosis at the hospital, it was confirmed that she had lumbar disc herniation. The hospital recommended surgical treatment, but the patient refused due to fear and came to our Chinese medicine clinic for treatment. After examination, the leg raising test was positive. She had to squat down to relieve the pain after walking for a period of time before she could walk. She was diagnosed with lumbar spinal stenosis, pale tongue, white fur, and stringy pulse. After using pure Chinese herbal decoctions for lumbar disc herniation that can promote blood circulation and remove blood stasis, strengthen bones and tonify the kidney, and promote blood circulation, combined with acupuncture, electroacupuncture, and cupping, after one and a half months of treatment, the patient's pain was significantly relieved. After another month of treatment, she was completely cured and has not relapsed so far, achieving satisfactory results.

[0071] 2. Ding Moumou, female, 65 years old, a teacher at the Fourth Middle School in Xingtai City, Hebei Province, visited the hospital in June 2014. She reported that she had suffered from lumbar disc herniation and bilateral knee synovitis for several years. After taking decoctions for lumbar disc herniation and bone hyperplasia, acupuncture, cupping, and electrotherapy, the patient did not pay attention to rest and her condition recurred. After four months of pure traditional Chinese medicine treatment, she was cured and has not had a relapse since then.

[0072] 3. Zhang, male, 63 years old, engineer of Xingtai Bluebird Furniture Factory, visited the hospital in May 2010. He suddenly could not get up in the morning and had severe pain in his waist. He went to the hospital and was diagnosed with lumbar disc herniation with occult aconal fissure. The hospital recommended surgery, but the patient refused. After receiving comprehensive treatment with decoctions for lumbar disc herniation mainly to promote blood circulation and remove blood stasis, strengthen bones and tonify kidney, and promote blood circulation, combined with acupuncture, cupping, and electrotherapy, he was advised to rest in bed during the treatment. After half a month of treatment, the patient's pain was significantly relieved. After another month of treatment with a secret recipe of decoctions for lumbar disc herniation, he recovered and has not relapsed so far, recovering like a normal person.

[0073] 4. Wu, female, 45, a police officer from Changji, Xinjiang, visited the hospital in July 2008. She said that she had been working hard in front of a computer for a long time, which compressed the nerves on the left side and made it impossible for her to stand or walk. She went to the hospital for treatment, and the hospital recommended surgery, but the patient refused. After an introduction and a telephone consultation, she was given a decoction for lumbar disc herniation and was advised to stay in bed. After two months of treatment, she recovered and has not had a relapse.

[0074] 5. Jia Moumou, female, 30 years old, employee of Xingtai Insurance Company, visited the hospital in May 2008. The patient walked with a limp, had scoliosis, needed support to walk, and had severe pain in the right leg. After a CT scan at the hospital, it was confirmed that she had lumbar 345 cone herniation and scoliosis. Her condition was relatively serious. She was treated with decoctions to promote blood circulation and remove blood stasis, promote blood circulation, strengthen bones and tonify kidneys, and eliminate the pathological products of congestion and edema. She was cured after more than two months of treatment with decoctions. Later, she relapsed due to fatigue, and continued to take decoctions for lumbar disc herniation. She was cured in a short period of half a month. There were no side effects of the treatment and recovery, and she has resumed normal life ever since.

[0075] 6. Huang, male, 45 years old, security worker at Xinjiang Petrochemical, visited the hospital in June 2009. He had low back pain, especially difficulty getting up early in the morning, which had recurred for more than ten years. After taking pure decoction treatment for lumbar disc herniation for half a month, he got significant relief, his low back pain was reduced, he was able to move well, and his self-confidence was restored.

[0076] 7. Guo Moumou, male, 16 years old, a junior high school student in Xingtai, fell to the ground due to an injury while playing football. He had back pain and could not stand for a long time. The hospital CT confirmed lumbar disc herniation. He was bedridden for a week and had difficulty walking. After a month of treatment with decoctions, he promoted blood circulation, removed blood stasis, dredged the meridians, and relieved edema. Half a year later, he fell down and had back pain again. He continued to take decoctions for lumbar disc herniation and recovered. He now delivers takeout.

[0077] The above description of the disclosed embodiments enables one skilled in the art to implement or use the present invention. Various modifications to these embodiments will be apparent to one skilled in the art, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the present invention. Therefore, the present invention will not be limited to the embodiments shown herein, but rather to the widest scope consistent with the principles and novel features disclosed herein.

Claims

1. A decoction for treating lumbar disc herniation, characterized in that: The raw material drug comprising the following parts by weight is prepared: 35-45 parts of buffalo horn slices, 8-10 parts of angelica sinensis, 8-10 parts of achyranthes bidentata, 13-15 parts of parasitic herb, 12-15 parts of chuanxiong, 8-10 parts of cassia twig, 11-13 parts of drynariae, 24-28 parts of astragalus, 20-25 parts of black beans, 15-20 parts of notopterygium, 15-20 parts of corydalis, 3-8 parts of serpentine, and 8-10 parts of papaya.

2. A decoction for treating lumbar disc herniation according to claim 1, characterized in that: Including the following raw materials by weight: 40 parts of buffalo horn slices, 9 parts of angelica sinensis, 9 parts of achyranthes bidentata, 14 parts of parasitic herb, 13 parts of chuanxiong, 9 parts of cassia twig, 12 parts of drynariae, 26 parts of astragalus, 23 parts of black beans, 18 parts of notopterygium, 17 parts of corydalis, 5 parts of serpentines, and 9 parts of papaya.

3. A method for preparing a decoction for treating lumbar disc herniation, characterized in that: The following steps are involved: (1) Weighing each raw material according to the decoction for treating lumbar disc herniation according to claim 1 or 2; (2) Place the corydalis in a pot and fry over low heat until the surface is melted and bubbles appear. Spray rice vinegar on it and continue frying until the outer layer is bright and translucent. Remove from the pot and let cool. (3) Put water buffalo horn slices, angelica, Achyranthes bidentata, mistletoe, Chuanduan, cinnamon twig, drynaria, astragalus, black bean, Notopterygium wilfordii, Corydalis yanhusuo, black-spotted snake and papaya into a decoction container and soak in water; (4) After soaking, the raw medicinal materials are naturally boiled over high heat, then slowly simmered over low heat, and then the heat is turned off. The raw medicinal materials are cooled and taken orally.

4. The method for preparing a decoction for treating lumbar disc herniation according to claim 3, characterized in that: In step (2), the mass ratio of Corydalis yanhusuo to rice vinegar is 100:(7-10).

5. The method for preparing a decoction for treating lumbar disc herniation according to claim 3, characterized in that: In step (3), the mass ratio of water added to the raw material drug is (8-10):1, and the soaking time is 40-45 minutes.

6. The method for preparing a decoction for treating lumbar disc herniation according to claim 3, characterized in that: In step (4), the time for slow frying over low heat is 20-25 minutes, and the mixture is taken orally after cooling to 37-40°C.