A vaccine preparation device

Abstract

The present invention relates to the technical field of vaccine preparation, and specifically discloses a vaccine preparation device, comprising a stirring tank, a driving mechanism and a stirring mechanism, wherein a spoiler mechanism is installed on the inner side of the stirring tank, a dust collecting mechanism is arranged on the outer side of the stirring mechanism, and a lifting mechanism for driving the dust collecting mechanism to move out liquid raw materials is installed on the driving mechanism; the spoiler mechanism comprises a plurality of adjusting components and a plurality of spoiler components, the spoiler components are rotatably connected to the adjusting components, the spoiler components comprise a plurality of spoiler plates arranged at equal intervals, and the spoiler plates can form shear with the stirring mechanism; in the vaccine preparation device of the present invention, when powder raw materials are added, a sleeve drives an impeller on the stirring mechanism to rotate rapidly, so that negative pressure is generated near the impeller, and at this time, the powder raw materials raised in the stirring tank move closer to the impeller under the action of the negative pressure, so as to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank, thereby reducing the difficulty of cleaning the stirring tank.

Description

Technical Field

[0001] The present invention relates to the technical field of vaccine preparation, and particularly relates to a vaccine preparation device. Background Art

[0002] A vaccine refers to a biological product used for vaccination prepared from various pathogenic microorganisms. Among them, vaccines prepared from bacteria or spirochetes are also called bacterins. Vaccines are divided into live vaccines and inactivated vaccines. Commonly used live vaccines include BCG vaccine, poliomyelitis vaccine, measles vaccine, plague vaccine, etc. Commonly used inactivated vaccines include pertussis vaccine, typhoid vaccine, meningococcal vaccine, cholera vaccine, etc. The production time of different vaccines varies. Some vaccines may take 22 months to complete the preparation of one batch. The development of vaccines is a long and complex process, and the cost is very high. Vaccination is the most economical and effective public health intervention measure for preventing and controlling infectious diseases, and it is also an effective means for families to reduce the occurrence of diseases among members and reduce medical expenses. When preparing vaccines, a mixing device is required to mix different vaccine raw materials to ensure the effectiveness and subsequent activity of the vaccines.

[0003] The Chinese patent application document with the authorization announcement number CN214416228U discloses a mixing and stirring device for veterinary vaccine production. This mixing and stirring device for veterinary vaccine production includes a box body. A first cavity is opened inside the box body. A material cylinder is arranged in the middle of the first cavity. A second cavity is opened inside the material cylinder. A stirring rod is arranged inside the second cavity. Stirring blades are evenly arranged at the bottom rod body of the stirring rod. Connecting blocks are evenly and fixedly installed on the left and right sides of the material cylinder. Rollers are installed inside the connecting blocks. Through the cooperation of bevel gears, the stirring rod, pulleys, ultraviolet sterilization lamp rollers and turntables, the material cylinder can rotate while the stirring rod mixes the vaccine raw materials.

[0004] However, the structural design of the above-mentioned related technology: Although it can clean and sterilize the inside of the mixing tank, during the process of adding powder raw materials to the mixing tank, the powder is likely to diffuse during feeding, resulting in some powder adhering to the inner wall of the pipeline and being unable to contact the liquid raw materials, thereby affecting the preparation quality of the vaccine, increasing the cleaning difficulty of the subsequent mixing tank, and the large amount of powder raw materials is likely to form lumps when encountering liquid raw materials, thus affecting the mixing effect of the vaccine raw materials.

[0005] Therefore, a vaccine preparation device is proposed to facilitate solving the problems raised above. Summary of the Invention

[0006] The present invention provides a vaccine preparation device, aiming to solve the problems in the related technology that the powder raw materials are prone to diffuse and adhere to the inner wall of the tank during the addition process, and are prone to form lumps in the liquid raw materials.

[0007] The vaccine preparation device of the present invention comprises a stirring tank, a driving mechanism and a stirring mechanism, wherein a flow disturbance mechanism is installed on the inner side of the stirring tank, a dust collecting mechanism is provided on the outer side of the stirring mechanism, and a lifting mechanism is installed on the driving mechanism for driving the dust collecting mechanism to remove liquid raw materials;

[0008] The flow-disturbing mechanism comprises a plurality of adjusting components and a plurality of flow-disturbing components, the flow-disturbing components are rotatably connected to the adjusting components, the flow-disturbing components comprise a plurality of flow-disturbing plates arranged at equal intervals, the flow-disturbing plates can form a shearing action with the stirring mechanism to shear the powder raw materials agglomerated in the liquid raw materials;

[0009] The dust collecting mechanism includes a dust collecting component arranged on the outside of the stirring mechanism, a limiting component rotatably connected to the outside of the dust collecting component, and two dust blocking components elastically slidably connected to the limiting component in the transverse direction; the dust collecting component includes a sleeve and an impeller installed on the sleeve, and the impeller can rotate independently on the stirring mechanism; the dust blocking component includes an arc-shaped baffle, which is located on the outside of the impeller.

[0010] When adding powder raw materials, the sleeve is driven upward by the lifting mechanism. At this time, the sleeve drives the impeller to move out the liquid raw materials and closes the two baffles. While the impeller moves out the liquid raw materials, the spoiler approaches the stirring mechanism under the action of the adjusting component, and then the sleeve drives the impeller to rotate rapidly on the stirring mechanism to generate negative pressure near the impeller. At this time, the powder raw materials raised in the stirring tank move closer to the impeller under the action of negative pressure. At the same time, the baffle prevents the adsorbed powder raw materials from being thrown to the inner wall of the stirring tank by the impeller to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank, thereby reducing the difficulty of cleaning the stirring tank. During the rapid rotation of the impeller, the stirring mechanism continues to rotate at the original speed in the liquid raw material and forms shear with the spoiler.

[0011] Preferably, the driving mechanism includes a motor 1 and an acceleration assembly, the motor 1 is connected to the stirring mechanism, the acceleration assembly can drive the impeller to rotate independently, the acceleration assembly includes a motor 2, a connecting shaft and a gear 1, the connecting shaft is installed on the motor 2, and the gear 1 is installed on the connecting shaft.

[0012] Preferably, the stirring mechanism comprises a stirring shaft, an external spline sleeve and a plurality of stirring blades, the external spline sleeve is mounted on the stirring shaft, and the plurality of stirring blades are evenly distributed on the outside of the stirring shaft.

[0013] Preferably, the dust collecting assembly further comprises an inner spline cylinder and gear 2, wherein the inner spline cylinder is mounted on the inner side of the sleeve, the inner spline cylinder is inserted on the outer spline sleeve, and the gear 2 is mounted on the outer side of the sleeve and can mesh with gear 1.

[0014] When the internal spline cylinder is inserted onto the external spline sleeve, the stirring shaft drives the sleeve on the internal spline cylinder to rotate synchronously through the external spline sleeve. At this time, the sleeve can drive the impeller to stir the vaccine raw materials in the stirring tank. When the internal spline cylinder is separated from the external spline sleeve, the second gear meshes with the first gear. At this time, the second motor can drive the impeller to rotate rapidly through the second gear on the first gear to form a negative pressure.

[0015] Preferably, the limiting component includes a lifting frame and two elastic connecting pieces. The lifting frame is rotatably connected to the outside of the sleeve, and the two elastic connecting pieces are respectively distributed on both sides inside the lifting frame.

[0016] Preferably, the elastic connecting piece includes a movable block, a connecting plate and a second wedge block. The movable block is elastically slidably connected to the inner bottom wall of the lifting frame in the transverse direction. The baffle is arranged at the bottom of the movable block. The connecting plate is installed on one side of the movable block, and the second wedge block is installed on the connecting plate.

[0017] The second wedge block can drive the movable block to slide on the inner bottom wall of the lifting frame through the connecting plate, so as to drive the two baffles to approach or move away from each other.

[0018] Preferably, the flow disturbing mechanism further includes a lifting component, and the adjusting component is arranged at the bottom of the lifting component.

[0019] Preferably, the adjusting component includes a support frame, a rotating cylinder, a limiting plate, a spiral groove, a movable rod and a limiting rod. The support frame is installed on the inner wall of the stirring tank. The rotating cylinder is rotatably connected to the inside of the support frame. The limiting plate is installed on the rotating cylinder. The movable rod is elastically slidably connected to the inside of the rotating cylinder in the vertical direction. The limiting rod is installed on the movable rod. The spiral groove is opened on the inner side of the rotating cylinder, and a vertical groove extending vertically downward is opened at the bottom end of the spiral groove. The limiting rod is located in the vertical groove of the rotating cylinder.

[0020] When the movable rod moves upward on the rotating cylinder, the movable rod can drive the limiting rod to move in the spiral groove, so as to drive the limiting plate on the rotating cylinder to rotate in the support frame. When the movable rod resets, it can drive the limiting plate to reset.

[0021] Preferably, the flow disturbing component further includes a rotating rod and a fixing column. The rotating rod is rotatably connected to the support frame. The top end of the rotating rod is located inside the support frame. The fixing column is installed at the edge position of the top end of the rotating rod. The limiting plate is sleeved on the outside of the fixing column. A plurality of the flow disturbing plates are equidistantly installed on the rotating rod.

[0022] When the limiting plate rotates, the limiting plate can drive the flow disturbing plates on the rotating rod to rotate through the fixing column, so as to form a shear between the flow disturbing plates and the stirring blades.

[0023] Preferably, the lifting assembly includes a connecting ring, two connecting rods and two first wedges. The top end of the movable rod is installed at the bottom end of the connecting ring. The two connecting rods are respectively installed on both sides of the top end of the connecting ring. Both of the two connecting rods penetrate through the bottom of the lifting frame and extend into the interior of the lifting frame. The two first wedges are respectively installed at the top ends of the two connecting rods and are adapted to the second wedge.

[0024] Adopting the above technical solution, the beneficial effects of the present invention are as follows:

[0025] 1. When adding the powder raw material, the lifting mechanism drives the sleeve to move upward. At this time, the sleeve drives the impeller to move out of the liquid raw material, and the two baffles are closed. While the impeller moves out of the liquid raw material, the spoiler moves closer to the stirring mechanism under the action of the adjusting assembly. Then the sleeve drives the impeller to rotate rapidly on the stirring mechanism, generating negative pressure near the impeller. At this time, the powder raw material lifted in the mixing tank moves closer to the impeller under the action of the negative pressure. At the same time, the baffle prevents the adsorbed powder raw material from being thrown by the impeller to the inner wall of the mixing tank, so as to avoid a large amount of powder raw material adhering to the inner wall of the mixing tank, thereby reducing the cleaning difficulty of the mixing tank and ensuring the preparation quality of the vaccine.

[0026] 2. During the rapid rotation of the impeller, the stirring mechanism continues to rotate at the original speed in the liquid raw material and forms shear with the spoiler to shear the powder raw material that agglomerates after entering the liquid raw material, thereby improving the mixing effect of the vaccine raw materials. Description of the Drawings

[0027] Figure 1 It is a schematic diagram of the overall structure of a specific embodiment in the present invention.

[0028] Figure 2 It is a schematic diagram of the internal structure of the housing of a specific embodiment in the present invention.

[0029] Figure 3 It is a schematic diagram of the internal top view structure of the housing of a specific embodiment in the present invention.

[0030] Figure 4 It is a schematic diagram of the structure of the drive mechanism of a specific embodiment in the present invention.

[0031] Figure 5 It is a schematic diagram of the structure of the stirring mechanism of a specific embodiment in the present invention.

[0032] Figure 6 It is a schematic diagram of the internal structure of the dust collection mechanism of a specific embodiment in the present invention.

[0033] Figure 7 It is a schematic diagram of the structure of the lifting assembly of a specific embodiment in the present invention.

[0034] Figure 8Schematic diagram of the internal structure of the support frame in the specific embodiment of the present invention.

[0035] Figure 9 Schematic cross-sectional structure diagram of the rotating cylinder in the specific embodiment of the present invention.

[0036] Figure 10 Schematic diagram of the structure of the movable rod in the specific embodiment of the present invention.

[0037] Reference numerals:

[0038] 10, mixing tank; 11, housing; 12, cover; 13, feed pipe; 14, liquid inlet pipe; 15, discharge pipe;

[0039] 20, drive mechanism; 21, mounting frame; 22, motor one; 23, coupling; 24, connecting frame; 25, motor two; 26, connecting shaft; 27, gear one;

[0040] 30, lifting mechanism; 31, mounting plate; 32, motor three; 33, lead screw; 34, threaded plate; 35, sliding plate; 36, slider;

[0041] 40, mixing mechanism; 41, mixing shaft; 42, external spline sleeve; 43, mixing blade;

[0042] 50, turbulence mechanism; 51, adjustment component; 511, support frame; 512, support plate; 513, rotating cylinder; 514, limiting plate; 515, spiral groove; 516, movable rod; 517, spring one; 518, limiting rod; 52, turbulence component; 521, rotating rod; 522, turbulence plate; 523, fixed column; 53, lifting component; 531, connecting ring; 532, connecting rod; 533, wedge one;

[0043] 60, dust collection mechanism; 61, dust collection component; 611, sleeve; 612, chute; 613, internal spline cylinder; 614, gear two; 615, impeller; 62, limiting component; 621, lifting frame; 622, spring two; 623, movable block; 624, connecting plate; 625, wedge two; 63, dust blocking component; 631, baffle; 632, sliding rod. Detailed implementation manners

[0044] The embodiments of the present invention will be described in detail below. The examples of the embodiments are shown in the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain the present invention and should not be construed as limiting the present invention.

[0045] As Figures 1 to 10As shown, the vaccine preparation device of the present invention comprises a stirring tank 10, a driving mechanism 20, a lifting mechanism 30, a stirring mechanism 40, a spoiler mechanism 50 and a dust collecting mechanism 60. The driving mechanism 20 is arranged on the top of the stirring tank 10, and the lifting mechanism 30 is arranged on one side of the driving mechanism 20. The stirring mechanism 40 is rotatably connected to the inside of the stirring tank 10 and connected to the driving mechanism 20, and the spoiler mechanism 50 is installed on the inner side of the stirring tank 10. The dust collecting mechanism 60 is inserted on the outside of the stirring mechanism 40 and is rotatably connected to the lifting mechanism 30, and the driving mechanism 20 can drive the dust collecting mechanism 60 to rotate on the stirring mechanism 40.

[0046] During the process of preparing vaccines, the driving mechanism 20 drives the stirring mechanism 40 and the dust collecting mechanism 60 to rotate inside the stirring tank 10 to stir the liquid raw materials in the stirring tank 10. When powder raw materials need to be added, the lifting mechanism 30 drives the dust collecting mechanism 60 to move upward and separate from the liquid raw materials, and engage with the driving mechanism 20. At this time, the driving mechanism 20 drives the stirring mechanism 40 to continue stirring at the original speed, and the driving mechanism 20 drives the dust collecting mechanism 60 to accelerate the rotation, so that negative pressure is generated near the dust collecting mechanism 60, so as to bring the diffused powder raw materials closer to the dust collecting mechanism 60, so as to avoid a large amount of powder raw materials adhering to the inner wall of the stirring tank 10.

[0047] like Figures 1 to 4 As shown, the mixing tank 10 includes a shell 11, a cover 12, a feed pipe 13, a liquid inlet pipe 14 and a discharge pipe 15. The cover 12 is mounted on the top of the shell 11, and the feed pipe 13 and the liquid inlet pipe 14 are respectively mounted on both sides of the top of the cover 12, and the feed pipe 13 and the liquid inlet pipe 14 are both connected to the shell 11. The driving mechanism 20 is mounted on the top of the cover 12 and is located between the feed pipe 13 and the liquid inlet pipe 14. The discharge pipe 15 is mounted at the middle of the bottom end of the shell 11 to discharge the prepared vaccine out of the shell 11.

[0048] like Figures 1 to 2 and Figure 4 As shown, the driving mechanism 20 includes a mounting frame 21, a motor 22, a coupling 23 and an acceleration assembly. The mounting frame 21 is in a U-shape, and the acceleration assembly is mounted on the top of one side of the mounting frame 21. The bottom of the mounting frame 21 is mounted on the top of the cover body 12 and is located between the feed pipe 13 and the liquid inlet pipe 14, and the motor 22 is mounted on the top of the mounting frame 21. The coupling 23 is located inside the mounting frame 21, and the top end of the coupling 23 is mounted on the drive shaft of the motor 22, and the bottom end of the coupling 23 is mounted on the stirring mechanism 40.

[0049] The acceleration component includes a connecting frame 24, a second motor 25, a connecting shaft 26, and a first gear 27. The connecting frame 24 is mounted on the mounting frame 21, and the second motor 25 is mounted on the top of the connecting frame 24. The top end of the connecting shaft 26 is rotatably connected to the bottom of the connecting frame 24 and fixed to the drive shaft of the second motor 25. The first gear 27 is mounted at the bottom end of the connecting shaft 26, and the first gear 27 can mesh with the dust collection mechanism 60.

[0050] When the dust collection mechanism 60 moves up to the limit position, the dust collection mechanism 60 meshes with the first gear 27. At this time, the second motor 25 drives the dust collection mechanism 60 to rotate at an accelerated speed through the first gear 27 on the connecting shaft 26, so that the dust collection mechanism 60 generates negative pressure to collect the diffused powder raw materials.

[0051] Continue to refer to Figures 1 to 2 and Figure 4 As shown in the figure, the lifting mechanism 30 includes a mounting plate 31, a third motor 32, a lead screw 33, a threaded plate 34, a sliding plate 35, and a slider 36. The mounting plate 31 is mounted on one side of the mounting frame 21, and the third motor 32 is mounted on the top of the mounting plate 31. The top end of the lead screw 33 is rotatably connected to the bottom of the mounting plate 31 and fixed to the drive shaft of the third motor 32, and the bottom end of the lead screw 33 is rotatably connected to the top end of the cover body 12. The threaded plate 34 is threadedly connected to the outside of the lead screw 33, and the threaded plate 34 and the slider 36 are respectively mounted on both sides of the sliding plate 35. The sliding plate 35 is slidably connected to the inside of the mounting frame 21, and grooves for the threaded plate 34 and the slider 36 to slide up and down are respectively formed on both sides of the mounting frame 21. The sliding plate 35 is rotatably connected to the outside of the dust collection mechanism 60.

[0052] When the third motor 32 drives the threaded plate 34 to move up through the lead screw 33, the threaded plate 34 can drive the dust collection mechanism 60 to move up through the sliding plate 35, so that the dust collection mechanism 60 moves out of the liquid raw material, avoiding the liquid raw material being subjected to a large shear force when the dust collection mechanism 60 rotates at an accelerated speed.

[0053] As Figures 2 to 5 shown, the stirring mechanism 40 includes a stirring shaft 41, an external spline sleeve 42, and stirring blades 43. The stirring shaft 41 is located inside the housing 11, and the top end of the stirring shaft 41 penetrates through the cover body 12 and is mounted at the bottom end of the coupling 23. The external spline sleeve 42 is mounted on the outside of the top end of the stirring shaft 41, and the dust collection mechanism 60 is inserted outside the external spline sleeve 42. There are multiple stirring blades 43, and the multiple stirring blades 43 are mounted on the outside of the stirring shaft 41 along the length direction of the stirring shaft 41.

[0054] The first motor 22 can drive the stirring blade 43 to rotate inside the housing 11 through the stirring shaft 41 on the coupling 23. At the same time, the stirring shaft 41 can drive the dust collection mechanism 60 to rotate inside the housing 11 through the external spline sleeve 42 to stir the vaccine raw materials in the housing 11. When the dust collection mechanism 60 meshes with the first gear 27, the external spline sleeve 42 moves out of the dust collection mechanism 60 so that the dust collection mechanism 60 can rotate independently outside the stirring shaft 41.

[0055] As Figures 2 to 3 shown, the dust collection mechanism 60 includes a dust collection component 61, a limit component 62 and a dust blocking component 63. The dust collection component 61 is inserted outside the stirring shaft 41, the limit component 62 is rotatably connected to the outside of the dust collection component 61, there are two dust blocking components 63, and the two dust blocking components 63 are respectively slidably connected to both sides of the bottom of the limit component 62, and the two dust blocking components 63 are respectively located on both sides of the dust collection component 61.

[0056] As Figures 3 to 6 shown, the dust collection component 61 includes a sleeve 611, an internal spline cylinder 613, a second gear 614 and an impeller 615. The sleeve 611 is sleeved on the outer side of the top of the stirring shaft 41. A chute 612 for the up and down sliding of the external spline sleeve 42 is provided at the top of the sleeve 611. The top of the sleeve 611 penetrates through the cover body 12 and extends to the outside of the cover body 12. The sliding plate 35 is rotatably connected to the sleeve 611. The internal spline cylinder 613 is installed on the inner wall of the chute 612. In the initial state, the internal spline cylinder 613 is inserted outside the external spline sleeve 42. The second gear 614 is installed on the outer side of the top of the sleeve 611, and the impeller 615 is installed on the outer side of the bottom of the sleeve 611.

[0057] In the initial state, the internal spline cylinder 613 is inserted on the external spline sleeve 42. The stirring shaft 41 drives the sleeve 611 outside the internal spline cylinder 613 to rotate through the external spline sleeve 42. At this time, the sleeve 611 can drive the impeller 615 to rotate synchronously with the stirring shaft 41 to stir the liquid raw materials. When the sliding plate 35 moves upward, the sliding plate 35 drives the impeller 615 to move upward through the sleeve 611 to move the impeller 615 out of the liquid raw materials. At the same time, the sleeve 611 also drives the internal spline cylinder 613 to disengage from the external spline sleeve 42. When the sleeve 611 moves upward to the limit position, the second gear 614 on the sleeve 611 meshes with the first gear 27. At this time, the second motor 25 drives the impeller 615 to rotate rapidly through the first gear 27 on the second gear 614 so that a negative pressure is generated near the impeller 615, so that the diffused powder raw materials move closer to the middle of the housing 11 to avoid a large amount of powder raw materials adhering to the inner wall of the housing 11.

[0058] As Figure 3 and Figure 6As shown, the limit component 62 includes a lifting frame 621 and an elastic connecting member. The lifting frame 621 is rotatably connected to the outside of the sleeve 611 and is arranged above the impeller 615. There are two installation cavities inside the lifting frame 621. There are two elastic connecting members, and the two elastic connecting members are respectively distributed in the two installation cavities inside the lifting frame 621.

[0059] As Figure 3 and Figure 6 shown, the elastic connecting member includes a second spring 622, a movable block 623, a connecting plate 624, and a second wedge block 625. One end of the second spring 622 is installed on one side of the inner wall of the installation cavity in the lifting frame 621. The movable block 623 is installed at the other end of the second spring 622 and is slidably connected to the inner bottom wall of the installation cavity in the lifting frame 621. The dust-proof component 63 is installed at the bottom of the movable block 623. The connecting plate 624 is installed on one side of the movable block 623, and the second wedge block 625 is installed on one side of the connecting plate 624.

[0060] Continuing to refer to Figure 3 and Figure 6 shown, the dust-proof component 63 includes a baffle 631 and a slide rod 632. The shape of the baffle 631 is arc-shaped. In the initial state, there is a gap between the baffles 631 in the two dust-proof components 63, and the impeller 615 is located between the two baffles 631. The bottom end of the slide rod 632 is installed on the top of the baffle 631. The top end of the slide rod 632 penetrates the bottom of the lifting frame 621 and is installed at the bottom of the movable block 623. A groove for the horizontal sliding of the slide rod 632 is provided at the bottom of the lifting frame 621.

[0061] When the sleeve 611 moves upward, the sleeve 611 drives the lifting frame 621 to move upward synchronously. At this time, the lifting frame 621 drives the baffle 631 on the slide rod 632 to move upward through the movable block 623. During the upward movement of the lifting frame 621, under the limitation of the lifting component 53, the second wedge block 625 can be pushed to move. At this time, the second wedge block 625 can drive the two baffles 631 to close through the movable block 623 on the connecting plate 624, so as to prevent the powder adsorbed by negative pressure from being thrown towards the inner wall of the housing 11.

[0062] As Figures 2 to 3 shown, the flow disturbance mechanism 50 includes an adjustment component 51, a flow disturbance component 52, and a lifting component 53. There are multiple adjustment components 51, and the multiple adjustment components 51 are installed on the inner wall of the housing 11 in a circular array centered on the axis of the housing 11. The number of the flow disturbance components 52 is the same as that of the adjustment components 51 and is rotatably connected to the adjustment components 51. The multiple adjustment components 51 are all arranged at the bottom of the lifting component 53.

[0063] As Figure 3 and Figures 7 to 10As shown, the adjusting assembly 51 includes a support frame 511, a support plate 512, a rotating cylinder 513, a limiting plate 514, a spiral groove 515, a movable rod 516, a first spring 517, and a limiting rod 518. The support frame 511 is installed on one side of the inner wall of the housing 11. Bumps extend from both the top and bottom of the side of the support frame 511 facing the axis of the housing 11. The support plate 512 is installed above the inside of the support frame 511, and the rotating cylinder 513 is rotatably connected to the top of the support plate 512. The limiting plate 514 is installed on the outer side of the top of the rotating cylinder 513, and a strip-shaped groove is provided on the limiting plate 514.

[0064] The movable rod 516 is slidably connected to the inside of the rotating cylinder 513. The top of the movable rod 516 passes through the top of the support frame 511 and is installed on the lifting assembly 53. The top of the first spring 517 is installed at the bottom end of the movable rod 516, and the bottom of the first spring 517 is installed on the top of the support plate 512. The limiting rod 518 is installed at the bottom of one side of the movable rod 516. The spiral groove 515 is provided on the inner side of the rotating cylinder 513, and a vertical groove extending vertically downward is provided at the bottom end of the spiral groove 515. In the initial state, the limiting rod 518 is located in the vertical groove of the rotating cylinder 513.

[0065] As Figure 3 、 Figure 5 and Figures 7 to 8 shown, the flow disturbing assembly 52 includes a rotating rod 521, flow disturbing plates 522, and fixing columns 523. The rotating rod 521 is rotatably connected between the two bumps of the support frame 511, and the top of the rotating rod 521 is located inside the support frame 511. The fixing column 523 is installed at the edge position of the top of the rotating rod 521, and the limiting plate 514 is sleeved on the outside of the fixing column 523. There are multiple flow disturbing plates 522, and the multiple flow disturbing plates 522 are equidistantly installed on the outside of the rotating rod 521 along the length direction of the rotating rod 521. The flow disturbing plates 522 in adjacent two flow disturbing assemblies 52 are staggered, and the flow disturbing plates 522 in multiple flow disturbing assemblies 52 are all staggered with the stirring blades 43. In the initial state, the end of the flow disturbing plate 522 is close to the inner wall of the housing 11.

[0066] Through the flow disturbing plates 522 in the multiple flow disturbing assemblies 52, the disturbance of the liquid raw material can be increased during stirring, so as to further improve the stirring effect.

[0067] As Figure 3 、 Figure 6 and Figure 8As shown in the figure, the lifting assembly 53 includes a connecting ring 531, a connecting rod 532, and a first wedge block 533. The movable rods 516 in the plurality of adjusting assemblies 51 are all installed at the bottom end of the connecting ring 531. The number of the connecting rods 532 and the first wedge blocks 533 is two. The two connecting rods 532 are respectively installed on both sides of the top end of the connecting ring 531. The two connecting rods 532 penetrate through the bottom of the lifting frame 621 and extend into the interior of the lifting frame 621. The two first wedge blocks 533 are respectively installed at the top ends of the two connecting rods 532 and are adapted to the second wedge block 625.

[0068] During the upward movement of the lifting frame 621, the second wedge block 625 moves upward synchronously. At this time, under the action of the first wedge block 533, the second wedge block 625 can be pushed to slide in the lifting frame 621. When the second wedge block 625 moves, the two baffle plates 631 approach and close to each other. As the lifting frame 621 continues to move upward, the lifting frame 621 drives the connecting ring 531 to move upward through the first wedge block 533. During the upward movement of the connecting ring 531, the movable rod 516 drives the limiting rod 518 to move in the spiral groove 515, thereby driving the rotating cylinder 513 to rotate. At this time, the rotating cylinder 513 pushes the rotating rod 521 on the fixed column 523 to rotate through the limiting plate 514, and the rotating rod 521 drives the end of the spoiler 522 to face the axis of the housing 11, so that when the stirring blade 43 rotates, it can form a shear with the spoiler 522 to shear the powdered raw material agglomerated in the liquid raw material, thereby improving the mixing effect of the powdered raw material and the liquid raw material.

[0069] Working principle: When preparing the vaccine, first add the liquid raw material into the housing 11 through the liquid inlet pipe 14. At this time, the first motor 22 drives the stirring blade 43 to rotate inside the housing 11 through the stirring shaft 41. At the same time, the stirring shaft 41 can drive the impeller 615 to rotate inside the housing 11 through the external spline sleeve 42 to stir the liquid raw material in the housing 11.

[0070] When it is necessary to add the powdered raw material, the third motor 32 drives the threaded plate 34 to move upward through the lead screw 33. The threaded plate 34 drives the impeller 615 on the sleeve 611 to move upward through the sliding plate 35 to move the impeller 615 out of the liquid raw material, and at the same time separates the internal spline cylinder 613 from the external spline sleeve 42. During the upward movement of the sleeve 611, the lifting frame 621 moves upward synchronously with the sleeve 611. At this time, the lifting frame 621 drives the baffle plate 631 on the sliding rod 632 to move upward through the movable block 623. During the upward movement of the lifting frame 621, the first wedge block 533 pushes the second wedge block 625 to slide in the lifting frame 621, so that the two baffle plates 631 approach and close to each other. As the sleeve 611 continues to move upward, the lifting frame 621 drives the limiting rod 518 to move in the spiral groove 515 through the movable rod 516 on the connecting ring 531, thereby driving the rotating cylinder 513 to rotate. At this time, the limiting plate 514 pushes the rotating rod 521 on the fixed column 523 to rotate, and the rotating rod 521 drives the end of the spoiler 522 to face the axis of the housing 11.

[0071] When the sleeve 611 moves upward to the limit position, the second gear 614 on the sleeve 611 meshes with the first gear 27. Then, the second motor 25 drives the impeller 615 to rotate rapidly through the first gear 27 on the second gear 614, so as to generate a negative pressure near the impeller 615. At this time, the powder raw material is added into the housing 11 through the feed pipe 13, and the diffused powder raw material can be made to move closer to the middle of the housing 11 by the negative pressure generated near the impeller 615, so as to avoid a large amount of powder raw material adhering to the inner wall of the housing 11. After the powder raw material contacts the liquid raw material, the shearing force formed by the stirring blade 43 and the spoiler 522 can shear the powder raw material agglomerated in the liquid raw material, thereby improving the mixing effect of the powder raw material and the liquid raw material.

[0072] Although the embodiments of the present invention have been shown and described above, it can be understood that the above embodiments are exemplary and should not be construed as limiting the present invention. Those of ordinary skill in the art can make changes, modifications, substitutions, and variations to the above embodiments within the scope of the present invention.

Claims

1. A vaccine preparation device, comprising a stirring tank, a driving mechanism and a stirring mechanism, characterized in that A turbulence mechanism is installed inside the mixing tank, a dust collection mechanism is arranged outside the mixing mechanism, and a lifting mechanism for driving the dust collection mechanism to move out of the liquid raw material is installed on the driving mechanism; The turbulence mechanism includes a plurality of adjusting components and a plurality of turbulence components. The turbulence components are rotatably connected to the adjusting components. The turbulence components include a plurality of turbulence plates arranged at equal intervals. The turbulence plates can form a shear with the mixing mechanism to shear the powdered raw materials agglomerated in the liquid raw material; The dust collection mechanism includes a dust collection component arranged outside the mixing mechanism, a limiting component rotatably connected to the outside of the dust collection component, and two dust blocking components elastically sliding along the transverse direction on the limiting component; The dust collection component includes a sleeve and an impeller installed on the sleeve. The impeller can rotate independently on the mixing mechanism; The dust blocking component includes an arc-shaped baffle plate, and the baffle plate is located outside the impeller; The lifting mechanism includes a mounting plate, a motor three, a lead screw, a threaded plate, a sliding plate and a slider; The adjusting component includes a support frame, a rotating cylinder, a limiting plate, a spiral groove, a movable rod and a limiting rod. The support frame is installed on the inner wall of the mixing tank. The rotating cylinder is rotatably connected inside the support frame. The limiting plate is installed on the rotating cylinder. The movable rod is elastically slidably connected vertically inside the rotating cylinder. The limiting rod is installed on the movable rod. The spiral groove is opened on the inner side of the rotating cylinder. A vertical groove extending vertically downward is opened at the bottom of the spiral groove. The limiting rod is located in the vertical groove of the rotating cylinder.

2. The vaccine preparation device according to claim 1, wherein, The driving mechanism includes a motor one and an accelerating component. The motor one is connected to the mixing mechanism. The accelerating component can drive the impeller to rotate independently. The accelerating component includes a motor two, a connecting shaft and a gear one. The connecting shaft is installed on the motor two. The gear one is installed on the connecting shaft.

3. The vaccine preparation device according to claim 1, characterized in that, The mixing mechanism includes a mixing shaft, an external spline sleeve and a plurality of mixing blades. The external spline sleeve is installed on the mixing shaft. The plurality of mixing blades are evenly distributed outside the mixing shaft.

4. The vaccine preparation device according to claim 3, characterized in that, The dust collection component further includes an internal spline cylinder and a gear two. The internal spline cylinder is installed inside the sleeve. The internal spline cylinder is inserted on the external spline sleeve. The gear two is installed on the outside of the sleeve and can be engaged with the gear one.

5. The vaccine preparation device according to claim 4, characterized in that, The limiting component includes a lifting frame and two elastic connecting pieces. The lifting frame is rotatably connected to the outside of the sleeve. The two elastic connecting pieces are respectively distributed on both sides inside the lifting frame.

6. The vaccine preparation device according to claim 5, characterized in that, The elastic connecting piece includes a movable block, a connecting plate and a wedge block two. The movable block is elastically slidably connected along the transverse direction on the inner bottom wall of the lifting frame. The baffle plate is arranged at the bottom of the movable block. The connecting plate is installed on one side of the movable block. The wedge block two is installed on the connecting plate.

7. The vaccine preparation device according to claim 6, characterized in that, The turbulence mechanism further includes a lifting component, and the adjusting component is arranged at the bottom of the lifting component.

8. The vaccine preparation device according to claim 1, characterized in that, The turbulence component further includes a rotating rod and a fixing column. The rotating rod is rotatably connected to the support frame. The top end of the rotating rod is located inside the support frame. The fixing column is installed at the edge position of the top end of the rotating rod. The limiting plate is sleeved outside the fixing column. The plurality of turbulence plates are installed on the rotating rod at equal intervals.

9. The vaccine preparation device according to claim 7, characterized in that, The lifting assembly includes a connecting ring, two connecting rods, and two first wedges. The top end of the movable rod is installed at the bottom end of the connecting ring. The two connecting rods are respectively installed on both sides of the top end of the connecting ring. Both of the two connecting rods penetrate through the bottom of the lifting frame and extend into the interior of the lifting frame. The two first wedges are respectively installed at the top ends of the two connecting rods and are adapted to the second wedge.

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