Disintegration tester for extracting composition from natural product
By designing adjustment components in the disintegrator to control the axial reciprocating sliding and circumferential rotation of the item placement component, the problems of high equipment maintenance costs and unconvincing experimental data in the prior art are solved, and more accurate drug simulation and equipment life extension are achieved.
Patent Information
- Application Number
- CN202510132452.3
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-02-06
- Publication Date
- 2025-05-06
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
When the existing disintegrator simulates the gastric juice environment, the up and down movement of the drug placement rack leads to large losses of the electric telescopic rod, high maintenance costs, and it is difficult to simulate the real situation of the drug in the stomach and intestines, resulting in unconvincing experimental data.
A disintegrator for natural product extraction synthetic substances was designed, and the adjustment component was used to control the item placement component to slide axially and reciprocate and circumferentially. Synchronous rotation was achieved through the transmission belt, simulating the movement of medicines in the stomach and intestines.
It effectively reduces mechanical wear and extends the service life of the equipment, and at the same time more accurately simulates the movement of drugs in the stomach and intestines, improving the persuasiveness of experimental data.
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Figure CN119936328A_ABST
Abstract
Description
Technical Field
[0001] The invention relates to the technical field of disintegration instruments, in particular to a disintegration instrument used for extracting and synthesizing natural products. Background Art
[0002] Natural product extracts and synthetics refer to compounds with specific biological activities extracted from plants, animals, minerals and other resources in nature, or analogs obtained by chemical or biological synthesis of these natural compounds. These compounds have important application values in many fields such as medicine, food, cosmetics and agriculture. Many natural products and their synthetics are used as drugs, such as antibiotics, anti-tumor drugs and anti-inflammatory drugs.
[0003] The main function of the disintegration instrument is to simulate the gastric fluid environment and test the disintegration time of drug preparations in the simulated gastric fluid. This is crucial to ensure that the active ingredients of the drug can be released in time in the gastrointestinal tract.
[0004] Existing disintegration instruments, such as a drug testing disintegration instrument disclosed in Chinese patent publication number CN220752093U, drive a drug placement rack to move up and down through a lifting mechanism, dissolve the drug in the drug placement rack into the liquid in the beaker, and complete the drug disintegration experiment.
[0005] However, compared with the existing technologies in related fields, firstly, the up and down movement of the medicine rack requires the electric telescopic rod to continuously extend and retract, so the electric telescopic rod will suffer great wear and tear after long-term operation, resulting in high maintenance costs for the equipment; secondly, it is difficult to simulate the actual condition of the drug in the stomach and intestines only through the up and down reciprocating motion of the medicine rack, resulting in the final experimental data being difficult to be convincing. Summary of the invention
[0006] The object of the present invention is to solve at least one of the technical drawbacks.
[0007] The purpose of the present invention is to overcome the shortcomings of the prior art, solve the problems mentioned in the background technology, and provide a disintegration apparatus for extracting synthetic substances from natural products.
[0008] The objective of the present invention is achieved through the following technical scheme: a disintegration instrument for extracting synthetic substances from natural products, comprising a workbench, a heating assembly is arranged in front of the top of the workbench, two beakers are placed inside the heating assembly, both beakers are provided with object placement assemblies for circumferential rotation and axial sliding inside, and the positions of the workbench corresponding to the two object placement assemblies are provided with adjustment assemblies for controlling their circumferential rotation and axial sliding; the adjustment assembly comprises a turntable rotatably arranged on the top of the workbench, a fixed shaft is fixedly arranged at the front end of the turntable near the edge, a connecting rod is hinged on the outer surface of the fixed shaft, a hinge is hinged on the end of the connecting rod away from the fixed shaft, a rotating shaft is rotatably arranged at the end of the hinge away from the connecting rod, the rotating shaft is connected to the object placement assembly through the connecting assembly, a fixing ring is sleeved on the outer surface of the rotating shaft, two adjustment blocks are symmetrically fixedly arranged on the inner wall of the fixing ring, and two adjustment grooves are symmetrically opened on the outer surface of the rotating shaft, and the adjustment grooves are curved grooves.
[0009] Preferably, two electric push rods are symmetrically fixed on the rear side of the workbench, and lifting plates are fixedly installed on the output ends of the two electric push rods.
[0010] Preferably, a connecting shaft is fixedly provided at the rear ends of the two turntables, and a belt groove is provided on the outer surfaces of the two turntables, and the two belt grooves are connected by a transmission belt.
[0011] Preferably, a motor is fixedly mounted on one side of the top of the lifting plate, the output end of the motor is fixedly connected to one of the connecting shafts, a fixing block is fixedly mounted on the other side of the top of the lifting plate, and the other connecting shaft is rotatably matched with the fixing block.
[0012] Preferably, a rotation hole is provided on the fixed block at a position corresponding to the connecting shaft, and the connecting shaft is matched and connected to the rotation hole via a bearing.
[0013] Preferably, L-shaped fixing parts are fixedly provided on the outer surfaces of the two fixing rings, and the L-shaped fixing parts are fixedly installed on the lifting plate.
[0014] Preferably, a connecting column is fixedly provided at the top end of the rotating shaft, a rotating hole is opened at a position of the hinge corresponding to the connecting column, and the connecting column is matched and connected to the rotating hole through a bearing.
[0015] Preferably, the article placement assembly includes a placement piece, a plurality of placement cavities are provided inside the placement piece, a pressure block is slidably provided inside each of the plurality of placement cavities, and a filter is fixedly provided at the bottom of the placement piece.
[0016] Preferably, the connecting assembly includes an articulated frame fixedly arranged at the end of the rotating shaft, and an articulated block is fixedly arranged at the center of the top of the placement member, and the articulated block is hinged to the articulated frame through a pin shaft.
[0017] Preferably, the heating assembly comprises a water tank fixedly mounted on the top of the workbench, a heating element and a support platform are fixedly arranged inside the water tank, a water pipe is fixedly arranged on the side of the water tank, and placement holes are opened at positions of the water tank corresponding to the two beakers.
[0018] Beneficial effects:
[0019] The disintegrator for extracting synthetic substances from natural products can use the unidirectional rotation of the motor as a driving mode by setting an adjustment component, so that the adjustment component controls the article placement component to perform axial reciprocating sliding, thereby avoiding unnecessary mechanical wear and ensuring the service life of the equipment. At the same time, the cooperation between the adjustment block and the adjustment slot is utilized to make the rotating shaft perform circumferential rotation while axially sliding, so that the rotating shaft controls the article placement component to perform circumferential rotation while axially sliding, thereby better simulating the actual condition of the drug in the stomach and intestines, thereby effectively improving the experimental data of the equipment. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the present invention. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative labor.
[0021] Figure 1 This is a schematic diagram of a state where the article placement assembly of the present invention has not entered the beaker;
[0022] Figure 2 This is a schematic diagram of the state of the article placement assembly of the present invention after entering the beaker;
[0023] Figure 3 It is a structural schematic diagram of the heating component of the present invention;
[0024] Figure 4 It is a structural schematic diagram of the belt groove and the transmission belt of the present invention;
[0025] Figure 5 For the present invention Figure 4 A schematic diagram of the structure enlargement at the center A;
[0026] Figure 6 It is a structural schematic diagram of the regulating assembly of the present invention;
[0027] Figure 7 It is a schematic diagram of the split structure of the fixed ring and the rotating shaft of the present invention;
[0028] Figure 8 It is a schematic structural diagram of the connecting column of the present invention.
[0029] In the figure: 1. workbench; 2. heating component; 21. water tank; 22. heating element; 23. support table; 24. water pipe; 3. beaker; 4. object placement component; 41. placement element; 42. placement chamber; 43. pressure block; 44. filter; 5. adjustment component; 51. turntable; 511. connecting shaft; 512. belt groove; 513. transmission belt; 52. fixed shaft; 53. connecting rod; 54. hinge; 55. rotating shaft; 551. connecting column; 56. fixing ring; 561. L-shaped fixing element; 57. adjustment block; 58. adjustment groove; 6. connecting component; 61. articulated frame; 62. articulated block; 63. pin shaft; 7. electric push rod; 71. lifting plate; 8. motor; 9. fixing block. DETAILED DESCRIPTION
[0030] In the description of the present invention, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood by specific circumstances.
[0031] Additional aspects and advantages of the present invention will be further given in the following description in conjunction with the accompanying drawings, and in part will become apparent from the following description, or may be learned through practice of the present invention.
[0032] like Figures 1 to 8As shown, a disintegration instrument for extracting synthetic substances from natural products comprises a workbench 1, a heating assembly 2 is arranged in front of the top of the workbench 1, two beakers 3 are placed inside the heating assembly 2, and object placement assemblies 4 are arranged inside the two beakers 3 for circumferential rotation and axial sliding, and the positions of the workbench 1 corresponding to the two object placement assemblies 4 are arranged for controlling the circumferential rotation and axial sliding thereof; the adjustment assembly 5 comprises a turntable 51 rotatably arranged on the top of the workbench 1, a fixed shaft 52 is fixedly arranged at the front end of the turntable 51 near the edge, a connecting rod 53 is hinged on the outer surface of the fixed shaft 52, a hinge 54 is hinged on the end of the connecting rod 53 away from the fixed shaft 52, a rotating shaft 55 is rotatably arranged at the end of the hinge 54 away from the connecting rod 53, a connecting column 551 is fixedly arranged on the top of the rotating shaft 55, and the hinge A rotating hole is provided at the position corresponding to the connecting column 551 at 54, and the connecting column 551 is connected to the rotating hole through a bearing. The above-mentioned bearing can reduce the friction force of the rotating shaft 55 during rotation, and improve the stability of the rotating shaft 55 during rotation. The rotating shaft 55 is connected to the item placement component 4 through the connecting component 6. The outer surface of the rotating shaft 55 is sleeved with a fixing ring 56, and two adjusting blocks 57 are symmetrically fixed on the inner wall of the fixing ring 56. The outer surface of the rotating shaft 55 has two adjusting grooves 58 symmetrically provided, and the adjusting grooves 58 are curved grooves. The rear ends of the two turntables 51 are fixed with connecting shafts 511, and the outer surfaces of the two turntables 51 are provided with belt grooves 512. The two belt grooves 512 are connected by a transmission belt 513, and the transmission belt 513 can make the other turntable 51 rotate synchronously.
[0033] Two electric push rods 7 are symmetrically fixed on the rear side of the inside of the workbench 1, and a lifting plate 71 is fixedly installed on the output ends of the two electric push rods 7. A motor 8 is fixedly installed on one side of the top of the lifting plate 71, and the output end of the motor 8 is fixedly connected to one of the connecting shafts 511. A fixing block 9 is fixedly installed on the other side of the top of the lifting plate 71. The other connecting shaft 511 is rotatably matched with the fixing block 9. A rotating hole is opened at the position of the fixing block 9 corresponding to the connecting shaft 511, and the connecting shaft 511 is connected to the rotating hole through a bearing. The outer surfaces of the two fixing rings 56 are fixedly provided with L-shaped fixing parts 561, and the L-shaped fixing parts 561 are fixedly installed on the lifting plate 71.
[0034] After the item placement component 4 enters the beaker 3, the motor 8 is started so that the connecting shaft 511 drives the turntable 51 to rotate (at this time, the transmission belt 513 can be used to allow the other turntable 51 to rotate synchronously). When the turntable 51 rotates, the fixed shaft 52 drives the connecting rod 53 to move, so that the hinge 54 drives the rotating shaft 55. The rotating shaft 55 drives the item placement component 4 to slide back and forth axially through the connecting component 6. The cooperation between the adjusting block 57 and the adjusting groove 58 is used to make the rotating shaft 55 rotate circumferentially while sliding axially, so that the rotating shaft 55 controls the item placement component 4 to rotate circumferentially while sliding axially, thereby better simulating the actual condition of the medicine in the stomach and intestines.
[0035] The article placement component 4 includes a placement piece 41, a plurality of placement cavities 42 are provided inside the placement piece 41, a pressure block 43 is slidably provided inside the plurality of placement cavities 42, a filter screen 44 is fixedly provided at the bottom of the placement piece 41, and the connection component 6 includes an articulated frame 61 fixedly provided at the end of the rotating shaft 55, an articulated block 62 is fixedly provided at the center of the top of the placement piece 41, the articulated block 62 is articulated to the articulated frame 61 through a pin shaft 63, the articulated block 62 can be docked with the articulated frame 61, and then the articulated block 62 can be articulated to the articulated frame 61 through the pin shaft 63, thereby improving the convenience of installing or disassembling the article placement component 4.
[0036] The heating assembly 2 includes a water tank 21 fixedly mounted on the top of the workbench 1, a heating element 22 and a support platform 23 are fixedly disposed inside the water tank 21, a water pipe 24 is fixedly disposed on the side of the water tank 21, and placement holes are provided at the positions of the two beakers 3 in the water tank 21.
[0037] The workbench 1, heating assembly 2, beaker 3, object placement assembly 4, electric push rod 7 and motor 8 described in this application are all well-known technologies, so their specific structures and working principles are not described in detail.
[0038] The working process is as follows:
[0039] S1, such as Figures 1 to 3 As shown, when in use, water is first injected into the water tank 21 through the water pipe 24, and the injection of water is stopped when the water level reaches the standard line. Then, a suitable solution is selected according to the type of natural product to be extracted, and the solution is added to the beaker 3. Then, the beaker 3 is placed in the placement hole, and the water in the water tank 21 can be heated by the heating element 22.
[0040] S2, such as Figure 1 , Figure 2 , Figure 5 and Figure 7As shown, when the water is heated, the lifting plate 71 is first controlled to rise by two electric push rods 7, so that the lifting plate 71 drives the motor 8, the fixing block 9 and the adjusting assembly 5 to rise synchronously, and then the natural product to be extracted is placed in the placement cavity 42, and the pressing block 43 is placed from the top of the placement cavity 42. At this time, the articulated block 62 can be docked with the articulated frame 61, and then the articulated block 62 and the articulated frame 61 are hinged by the pin 63;
[0041] S3, such as Figure 1 , Figure 2 and Figure 5 As shown, after the article placement assembly 4 is installed, the lifting plate 71 is controlled to descend by two electric push rods 7, so that the article placement assembly 4 enters the interior of the beaker 3;
[0042] S4, such as Figures 1 to 7 As shown, after the object placement component 4 enters the beaker 3, the motor 8 is started, so that the connecting shaft 511 drives the turntable 51 to rotate (at this time, the transmission belt 513 can be used to make the other turntable 51 rotate synchronously). When the turntable 51 rotates, the fixed shaft 52 drives the connecting rod 53 to move, so that the hinge 54 drives the rotating shaft 55, and the rotating shaft 55 drives the object placement component 4 to slide back and forth axially through the connecting component 6;
[0043] S5, such as Figures 5 to 7 As shown, when the rotating shaft 55 slides back and forth axially, the cooperation between the adjusting block 57 and the adjusting groove 58 makes the rotating shaft 55 rotate circumferentially while sliding axially, so that the rotating shaft 55 controls the article placement component 4 to rotate circumferentially while sliding axially, thereby better simulating the real situation of the medicine in the stomach and intestines;
[0044] S6, such as Figures 1 to 7 As shown, after the equipment is used, the motor 8 is turned off, and then the lifting plate 71 is controlled to rise by two electric push rods 7, so that the lifting plate 71 drives the motor 8, the fixing block 9, the adjustment component 5 and the object placement component 4 to rise synchronously. At this time, the object placement component 4 and the adjustment component 5 can be separated to prepare for the next test work, and the beaker 3 is taken out to observe the disintegration result.
[0045] The above shows and describes the basic principles, main features and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments, and the above embodiments and descriptions are only for explaining the principles of the present invention. Without departing from the spirit and scope of the present invention, the present invention may have various changes and improvements, and these changes and improvements all fall within the scope of the present invention to be protected.
Claims
1. A disintegrator for extracting synthetic products from natural products, characterized in that: The invention comprises a workbench (1), wherein a heating assembly (2) is arranged in front of the top of the workbench (1), two beakers (3) are arranged inside the heating assembly (2), and an article placement assembly (4) is arranged inside the two beakers (3) so as to rotate circumferentially and slide axially, and an adjustment assembly (5) for controlling the circumferential rotation and axial sliding of the two article placement assemblies (4) is arranged at positions of the workbench (1) corresponding to the two article placement assemblies (4); The adjustment component (5) comprises a turntable (51) rotatably arranged on the top of the workbench (1); a fixed shaft (52) is fixedly arranged at a position near the edge of the front end of the turntable (51); a connecting rod (53) is hingedly connected to the outer surface of the fixed shaft (52); an end of the connecting rod (53) away from the fixed shaft (52) is hingedly connected to a hinge (54); an end of the hinge (54) away from the connecting rod (53) is rotatably provided with a rotating shaft (55); the rotating shaft (55) is connected to the article placement component (4) through a connecting component (6); a fixing ring (56) is sleeved on the outer surface of the rotating shaft (55); two adjusting blocks (57) are symmetrically fixedly arranged on the inner wall of the fixing ring (56); and two adjusting grooves (58) are symmetrically opened on the outer surface of the rotating shaft (55); and the adjusting grooves (58) are curved grooves.
2. The disintegration apparatus for extracting and synthesizing natural products according to claim 1, characterized in that: Two electric push rods (7) are symmetrically fixedly arranged on the rear side of the workbench (1), and lifting plates (71) are fixedly installed on the output ends of the two electric push rods (7).
3. The disintegration apparatus for extracting and synthesizing natural products according to claim 2, characterized in that: A connecting shaft (511) is fixedly provided at the rear ends of the two rotating disks (51), and a belt groove (512) is provided on the outer surfaces of the two rotating disks (51), and the two belt grooves (512) are connected by a transmission belt (513).
4. The disintegration apparatus for extracting and synthesizing natural products according to claim 3, characterized in that: A motor (8) is fixedly mounted on one side of the top of the lifting plate (71), and the output end of the motor (8) is fixedly connected to one of the connecting shafts (511). A fixing block (9) is fixedly mounted on the other side of the top of the lifting plate (71), and the other connecting shaft (511) is rotatably matched with the fixing block (9).
5. The disintegration apparatus for extracting and synthesizing natural products according to claim 4, characterized in that: The fixing block (9) is provided with a rotation hole at a position corresponding to the connecting shaft (511), and the connecting shaft (511) is matched and connected to the rotation hole via a bearing.
6. The disintegration apparatus for extracting and synthesizing natural products according to claim 2, characterized in that: The outer surfaces of the two fixing rings (56) are both fixedly provided with L-shaped fixing members (561), and the L-shaped fixing members (561) are both fixedly mounted on the lifting plate (71).
7. The disintegration apparatus for extracting and synthesizing natural products according to claim 1, characterized in that: A connecting column (551) is fixedly provided at the top end of the rotating shaft (55), a rotating hole is opened at a position of the hinge (54) corresponding to the connecting column (551), and the connecting column (551) is matched and connected to the rotating hole via a bearing.
8. The disintegration apparatus for extracting and synthesizing natural products according to claim 1, characterized in that: The article placement assembly (4) comprises a placement piece (41), a plurality of placement cavities (42) are provided inside the placement piece (41), a pressing block (43) is slidably provided inside each of the plurality of placement cavities (42), and a filter screen (44) is fixedly provided at the bottom of the placement piece (41).
9. The disintegration apparatus for extracting and synthesizing natural products according to claim 8, characterized in that: The connecting assembly (6) comprises an articulated frame (61) fixedly arranged at the end of the rotating shaft (55), and an articulated block (62) is fixedly arranged at the center of the top of the placement member (41), and the articulated block (62) is articulated with the articulated frame (61) via a pin shaft (63).
10. The disintegration apparatus for extracting and synthesizing natural products according to claim 1, characterized in that: The heating assembly (2) comprises a water tank (21) fixedly mounted on the top of the workbench (1); a heating element (22) and a support platform (23) are fixedly arranged inside the water tank (21); a water pipe (24) is fixedly arranged on the side of the water tank (21); and placement holes are provided in the water tank (21) at positions corresponding to the two beakers (3).
Citation Information
Patent Citations
Drug detection disintegration tester
CN220752093U