Double-blocking cell cycle operation teaching model
By designing a dual-blocking cell cycle operation teaching model containing installation mechanism and drive mechanism, the problem that the existing model cannot help students understand the principle of dual-blocking cell cycle in complex situations is solved, and vivid simulation of the cell cycle and 3H-TDR dual-blocking effects and students' understanding are achieved.
Patent Information
- Application Number
- CN202510319845.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-18
- Publication Date
- 2025-05-06
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The existing cell demonstration model has simple structure and function, and cannot help students understand the principle of double blocking cell cycle in complex situations.
Design a dual-blocking cell cycle operation teaching model, including installation mechanism and drive mechanism. The installation mechanism consists of a base plate, a housing cover, a transparent top plate, a partition cylinder and a pin. The driving mechanism consists of a motor mounting base and a turntable. The turntable is driven to rotate by driving the motor, simulating different stages of the cell cycle and the double blocking effect of 3H-TDR.
This model can relatively simple and efficiently express the dual blocking effect of cell cycle progression and 3H-TDR, helping students to understand the principles of cell cycle and double blocking more deeply.
Smart Images

Figure CN119942884A_ABST
Abstract
Description
Technical Field
[0001] The invention belongs to the technical field of teaching devices, and in particular relates to a double-blocking cell cycle operation teaching model. Background Art
[0002] When teaching cell cycle-related issues, in order to let students understand the specific cycle changes intuitively and specifically, it is generally necessary to use physical models to simulate the cell cycle state. In the double blocking experiment of 3H-TDR labeling with the cell cycle as the background, since the synchronization of the cell cycle involves the concept of life, scientific exploration, social responsibility and other investigations, the 3D model that can dynamically simulate various situations can effectively help students understand its principles;
[0003] However, the existing cell demonstration models are mostly simple in structure and function, and cannot help students understand the principles in complex situations. Students cannot understand the double blocking principle in a simple and profound way.
[0004] To this end, those skilled in the art have proposed a double-blocking cell cycle operation teaching model to solve the problems raised by the background technology.
[0005] The above information disclosed in this background technology is only used to increase the understanding of the background technology of the present invention and therefore, it may include information that does not constitute the prior art known to a person of ordinary skill in the art. Summary of the invention
[0006] The purpose of the present invention is to provide a double-blocked cell cycle operation teaching model to solve the problems raised in the background technology.
[0007] To achieve the above object, the present invention provides the following technical solutions:
[0008] A double-blocked cell cycle operation teaching model, including:
[0009] An installation mechanism, the installation mechanism comprises a bottom plate and a accommodating outer cover fixedly mounted on the upper surface of the bottom plate, a transparent top plate is arranged on the upper surface of the accommodating outer cover, a cell inlet is provided on the transparent top plate, a separation cylinder is fixedly mounted on the lower surface of the cell inlet, the separation cylinder has a circular cylinder structure, a slot is provided on the upper surface of the transparent top plate, the number of the slots is six, and a first latch, a second latch, a third latch, a fourth latch, a fifth latch and a sixth latch are respectively plugged into the six slots;
[0010] The driving mechanism includes a motor mounting base fixedly mounted on the upper surface of the base plate and a turntable arranged inside the accommodating outer cover, a driving motor is installed inside the motor mounting base, one end of the driving motor includes an output shaft, a connecting hole is opened on the lower surface of the turntable, the connecting hole is plugged into the output shaft, the cross-sectional shape of the turntable is trapezoidal, a plurality of partition tracks are arranged on the upper surface of the turntable, and the partition cylinder is located above the turntable.
[0011] Preferably, a cell outlet is provided on a peripheral side of the containing outer cover, the position of the fifth latch is adapted to the position of the cell outlet for blocking the cell outlet, and the sixth latch is located at one end of the fifth latch.
[0012] Preferably, the first latch and the fourth latch are located on the same central axis.
[0013] Preferably, a discharge groove is provided on the peripheral side of the separation cylinder, the position of the third latch is adapted to the position of the discharge groove for blocking the discharge groove, and the second latch is located at one end of the third latch.
[0014] Preferably, the first latch, the second latch, the third latch, the fourth latch, the fifth latch and the sixth latch all include a handle and a partition fixedly connected to the lower surface of the handle.
[0015] Preferably, a wiring port is provided on the peripheral side of the containing outer cover, and the wiring port is electrically connected to the driving motor.
[0016] Compared with the prior art, the present invention has the following beneficial effects:
[0017] (1) The present invention sets a driving motor to drive the turntable to rotate, and the separation cylinder on the transparent top plate can divide the turntable into two inner and outer circles. In the initial state, the first pin and the second pin are pulled out. At this time, the small ball used to simulate the cell enters the inner circle on the turntable from the cell inlet. The driving motor can drive the turntable to rotate. At this time, the first pin and the second pin are inserted, that is, the state when 3H-TDR is doped is simulated. At this time, the baffle will automatically close, so that the small ball is blocked and rolls into the pipeline due to gravity, indicating that some cells stay in the G1 / S phase. At the same time, the cells in the S phase are blocked by the baffle and stay still, indicating that the cells in the S phase directly terminate the cell process. At this time, the third pin is pulled out, and the fourth pin on the same central axis as the third pin is inserted. At this time, the balls enter the outer circle through the discharge groove. Since the fourth pin and the third pin are on the same central axis, the balls in the inner and outer circles will rotate at the same speed, which can simulate the state when 3H-TDR is washed away. At this time, the whole pipeline rotates along with the cylindrical inclined plane, so that the cells in the G1 / S phase that stay there can run the cycle together. Through this device, the cell cycle and the double blocking effect of 3H-TDR can be relatively simply and effectively represented, which is convenient for students to understand. Finally, after the demonstration is completed, the fifth pin can be pulled out to open the cell outlet to let the balls out.
[0018] (2) The present invention has the advantages of low cost, convenient and fast operation, high model accuracy and high quality by setting up 3D printing teaching equipment. Moreover, the teaching model made by 3D printing technology can break through the limitations of traditional teaching facilities and provide richer and more diverse teaching resources. If the model is damaged, it can even be easily remade, which is very suitable for use as a teaching aid.
[0019] The above summary is for illustrative purposes only and is not intended to be limiting in any way. In addition to the illustrative aspects, embodiments and features described above, further aspects, embodiments and features of the present invention will be readily apparent by reference to the accompanying drawings and the following detailed description. BRIEF DESCRIPTION OF THE DRAWINGS
[0020] Figure 1 It is a schematic diagram of the three-dimensional structure of the present invention;
[0021] Figure 2 is a side view of the present invention;
[0022] Figure 3 It is a schematic diagram of the explosion structure of the present invention;
[0023] Figure 4 It is a schematic diagram of the specific structure of the first latch of the present invention.
[0024] In the figure: 1. bottom plate; 2. containing cover; 3. transparent top plate; 4. cell inlet; 5. first latch; 6. second latch; 7. third latch; 8. fourth latch; 9. fifth latch; 10. sixth latch; 11. wiring port; 12. separation cylinder; 13. discharge slot; 14. turntable; 15. connecting hole; 16. separation track; 17. motor mounting seat; 18. driving motor; 19. output shaft; 20. handle; 21. partition; 22. cell outlet. DETAILED DESCRIPTION
[0025] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.
[0026] Embodiment 1:
[0027] See also Figure 1-Figure 4 As shown, a double-blocked cell cycle operation teaching model includes:
[0028] The mounting mechanism comprises a bottom plate 1 and a housing 2 fixedly mounted on the upper surface of the bottom plate 1, a transparent top plate 3 is arranged on the upper surface of the housing 2, a cell inlet 4 is provided on the transparent top plate 3, a separation cylinder 12 is fixedly mounted on the lower surface of the cell inlet 4, and the separation cylinder 12 has a circular cylinder structure, and slots are provided on the upper surface of the transparent top plate 3, and the number of the slots is six, and the first latch 5, the second latch 6, the third latch 7, the fourth latch 8, the fifth latch 9 and the sixth latch 10 are respectively plugged into the six slots;
[0029] The driving mechanism includes a motor mounting base 17 fixedly mounted on the upper surface of the base plate 1 and a turntable 14 arranged inside the accommodating outer cover 2. A driving motor 18 is installed inside the motor mounting base 17. One end of the driving motor 18 includes an output shaft 19. A connecting hole 15 is opened on the lower surface of the turntable 14. The connecting hole 15 is plugged into the output shaft 19. The cross-sectional shape of the turntable 14 is trapezoidal. A plurality of partition tracks 16 are arranged on the upper surface of the turntable 14. The partition cylinder 12 is located above the turntable 14.
[0030] Specifically, a cell outlet 22 is opened on the side of the containing outer cover 2, the position of the fifth latch 9 is adapted to the position of the cell outlet 22 for blocking the cell outlet 22, and the sixth latch 10 is located at one end of the fifth latch 9.
[0031] Specifically, the first latch pin 5 and the fourth latch pin 8 are located on the same central axis.
[0032] Specifically, a discharge groove 13 is opened on the side surface of the separation cylinder 12 , and the position of the third latch 7 is adapted to the position of the discharge groove 13 for blocking the discharge groove 13 . The second latch 6 is located at one end of the third latch 7 .
[0033] As can be seen from the above, the device is provided with a driving motor 18 for driving the turntable 14 to rotate, and the separation cylinder 12 on the transparent top plate 3 can divide the turntable 14 into two inner and outer circles. In the initial state, the first latch 5 and the second latch 6 are pulled out. At this time, the small ball used to simulate the cell enters the inner circle on the turntable 14 from the cell inlet 4. The driving motor 18 can drive the turntable 14 to rotate. At this time, the first latch 5 and the second latch 6 are inserted, that is, the state when 3H-TDR is doped is simulated. At this time, the baffle will automatically close, so that the small ball is blocked and then rolls into the pipeline due to gravity, indicating that some cells stay in the G1 / S phase. At the same time, the cells in the S phase are blocked by the baffle and stay still, indicating that the cells in the S phase are directly Then terminate the cell process, pull out the third pin 7, and insert the fourth pin 8 on the same central axis as the third pin 7. At this time, the balls enter the outer circle through the discharge groove 13. Since the fourth pin 8 and the third pin 7 are on the same central axis, the balls in the inner and outer circles will rotate at the same speed, which can simulate the state when 3H-TDR is washed away. At this time, the entire pipeline rotates along with the cylindrical inclined plane, so that the cells in the G1 / S phase that are retained can run the cycle together. Through this device, the cell cycle and the double blocking effect of 3H-TDR can be relatively simply and effectively represented, which is convenient for students to understand. Finally, after the demonstration is completed, the fifth pin 9 can be pulled out to open the cell outlet 22 to discharge the balls.
[0034] Embodiment 2:
[0035] See also Figure 1-Figure 4 As shown, the first latch 5 , the second latch 6 , the third latch 7 , the fourth latch 8 , the fifth latch 9 and the sixth latch 10 all include a handle 20 and a partition 21 fixedly connected to the lower surface of the handle 20 .
[0036] Specifically, two sides of the receiving cover are provided with wiring ports 11 , and the wiring ports 11 are electrically connected to the driving motor 18 .
[0037] As can be seen from the above, this device has the advantages of low cost, convenient and fast operation, high model accuracy and high quality by setting up 3D printing teaching equipment. Moreover, the use of 3D printing technology to make teaching models can break through the limitations of traditional teaching facilities and provide richer and more diverse teaching resources. If the model is damaged, it can even be easily remade, which is very suitable for teaching aids.
[0038] The standard parts used in the present invention can all be purchased from the market, and the special-shaped parts can be customized according to the description and the drawings. The specific connection methods of each part adopt conventional means such as mature bolts, rivets, welding, etc. in the prior art. The machinery, parts and equipment all adopt conventional models in the prior art, and the circuit connection adopts the conventional connection method in the prior art, which will not be described in detail here. The contents not described in detail in this specification belong to the prior art known to professional and technical personnel in this field.
[0039] In the description of the present invention, the terms "first" and "second" are used for descriptive purposes only and should not be understood as indicating or implying relative importance or implicitly indicating the number of the indicated technical features. Therefore, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. "Multiple" means two or more, unless otherwise clearly and specifically defined.
[0040] In the present invention, unless otherwise clearly specified and limited, the terms "installed", "connected", "connected", "fixed" and the like should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, it can be the internal connection of two elements or the interaction relationship between two elements. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood according to specific circumstances.
[0041] In the present invention, unless otherwise clearly specified and limited, a first feature being "above" or "below" a second feature may mean that the first and second features are in direct contact, or the first and second features are in indirect contact through an intermediate medium. Moreover, a first feature being "above", "above" or "above" a second feature may mean that the first feature is directly above or obliquely above the second feature, or simply means that the first feature is higher in level than the second feature. A first feature being "below", "below" or "below" a second feature may mean that the first feature is directly below or obliquely below the second feature, or simply means that the first feature is lower in level than the second feature.
[0042] In the description of this specification, the description with reference to the terms "one embodiment", "some embodiments", "example", "specific example" or "some examples" etc. means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present invention. In this specification, the schematic representations of the above terms do not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner. In addition, those skilled in the art may combine and combine the different embodiments or examples described in this specification and the features of the different embodiments or examples, unless they are contradictory.
[0043] In the drawings of the embodiments disclosed in the present invention, only the structures related to the embodiments disclosed in the present invention are involved, and other structures can refer to the general design. In the absence of conflict, the same embodiment and different embodiments of the present invention can be combined with each other.
[0044] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.
Claims
1. A double-blocked cell cycle operation teaching model, characterized in that: include: A mounting mechanism, the mounting mechanism comprising a bottom plate (1) and a containing outer cover (2) fixedly mounted on the upper surface of the bottom plate (1); a transparent top plate (3) is arranged on the upper surface of the containing outer cover (2); a cell inlet (4) is provided on the transparent top plate (3); a separation cylinder (12) is fixedly mounted on the lower surface of the cell inlet (4); the separation cylinder (12) is a circular cylinder structure; a slot is provided on the upper surface of the transparent top plate (3); the number of the slots is six; a first latch (5), a second latch (6), a third latch (7), a fourth latch (8), a fifth latch (9) and a sixth latch (10) are respectively inserted into the six slots; A driving mechanism, the driving mechanism comprising a motor mounting seat (17) fixedly mounted on the upper surface of a base plate (1) and a turntable (14) arranged inside a housing (2); a driving motor (18) is installed inside the motor mounting seat (17); one end of the driving motor (18) comprises an output shaft (19); a connecting hole (15) is provided on the lower surface of the turntable (14); the connecting hole (15) is plugged into the output shaft (19); the cross-sectional shape of the turntable (14) is a trapezoid; a plurality of partition tracks (16) are provided on the upper surface of the turntable (14); and the partition cylinder (12) is located above the turntable (14).
2. A double-blocked cell cycle operation teaching model according to claim 1, characterized in that: A cell outlet (22) is provided on the side surface of the containing outer cover (2), the position of the fifth latch (9) is adapted to the position of the cell outlet (22) for blocking the cell outlet (22), and the sixth latch (10) is located at one end of the fifth latch (9).
3. A double-blocked cell cycle operation teaching model according to claim 1, characterized in that: The first latch pin (5) and the fourth latch pin (8) are located on the same central axis.
4. A double-blocked cell cycle operation teaching model according to claim 1, characterized in that: The side surface of the separation cylinder (12) is provided with a discharge groove (13); the position of the third latch (7) is adapted to the position of the discharge groove (13) for blocking the discharge groove (13); and the second latch (6) is located at one end of the third latch (7).
5. A double-blocked cell cycle operation teaching model according to claim 1, characterized in that: The first latch (5), the second latch (6), the third latch (7), the fourth latch (8), the fifth latch (9) and the sixth latch (10) all comprise a handle (20) and a partition (21) fixedly connected to the lower surface of the handle (20).
6. A double-blocked cell cycle operation teaching model according to claim 1, characterized in that: A wiring port (11) is provided on the peripheral side of the accommodating outer cover (2), and the wiring port (11) is electrically connected to the driving motor (18).