Tissue retraction device and delivery system

Abstract

Medical devices and methods of using medical devices are disclosed. An example tissue retraction device (22) includes a first tissue engaging member (52a) coupled to a resilient member (62) by a coupling assembly. The coupling assembly includes a first coupler body (36a, 136a) having a first end region and a first compression member (49a). Further, the first end region of the first coupler body is configured to extend into a portion of the lumen of the resilient member, and the compression member is designed to compress the resilient member onto the first coupler body such that the resilient member securely engages the coupler body.

Description

[0001] This application is a divisional of a Chinese application filed on April 30, 2019, with application number 201980029081.9 and invention name “Tissue Retraction Device and Delivery System”.

[0002] CROSS-REFERENCE TO RELATED APPLICATIONS

[0003] This application claims the benefit of priority to U.S. Provisional Application No. 62 / 665,441, filed on May 1, 2018, the entire disclosure of which is hereby incorporated by reference. Technical Field

[0004] The present disclosure relates to medical devices, and methods for making medical devices. More particularly, the present disclosure relates to a tissue retraction device and related delivery system. Background Art

[0005] A wide variety of in vivo medical devices have been developed for medical use, e.g., intravascular use. Some of these devices include guidewires, catheters, etc. These devices are manufactured by any of a variety of different manufacturing methods and can be used according to any of the various methods. Each of the known medical devices and methods has certain advantages and disadvantages. There is a continuing need to provide alternative medical devices and alternative methods for making and using medical devices. Summary of the invention

[0006] The present disclosure provides designs, materials, manufacturing methods, and use alternatives for medical devices. An example tissue retraction device includes a first tissue engaging member, which is coupled to a resilient member via a coupling assembly. The coupling assembly includes a first connector body, which has a first end region and a first compression member. In addition, the first end region of the first connector body is configured to extend into a portion of a lumen of the resilient member, and the compression member is designed to compress the resilient member against the first connector body so that the resilient member is securely engaged with the connector body.

[0007] Alternatively or in addition to any of the above embodiments, wherein the first end region of the first coupling body includes a channel extending around a circumference thereof.

[0008] Alternatively or in addition to any of the above embodiments, wherein the first compression member is designed to compress the resilient member into at least a portion of the channel of the first coupling body.

[0009] Alternatively or in addition to any of the above embodiments, wherein the compression member comprises a compression ring.

[0010] Alternatively or in addition to any of the above embodiments, wherein the compression member comprises sutures.

[0011] Alternatively or in addition to any of the above embodiments, wherein the coupling assembly further comprises a connecting member, wherein the connecting member is configured to couple the coupler body to the first tissue engaging member.

[0012] Alternatively or in addition to any of the above embodiments, wherein the connecting member comprises a post member and an attachment member, wherein the first end region of the post member is coupled to the attachment member, and wherein the post member is configured to extend through the aperture of the coupler body.

[0013] Alternatively or in addition to any of the above embodiments, the column member further comprises a second end region opposite the first end region, and wherein the first end region of the column member comprises a first diameter, and wherein the second end region of the column member comprises a second diameter greater than the first diameter.

[0014] Alternatively or in addition to any of the above embodiments, wherein the aperture comprises a first inner diameter, and wherein the second diameter of the post member is greater than the first inner diameter of the aperture.

[0015] Alternatively or in addition to any of the embodiments above, wherein the first tissue engaging member comprises a first tissue engaging portion and a first spring, and wherein the attachment member is designed to engage the first spring.

[0016] Alternatively or in addition to any of the above embodiments, wherein the attachment member is generally C-shaped.

[0017] Alternatively or in addition to any of the above embodiments, wherein the attachment member comprises a first fitting and a second fitting, and wherein the first fitting and the second fitting are designed to mate with each other.

[0018] Alternatively or in addition to any of the above embodiments, wherein the first fitting and the second fitting are designed to couple the first spring to a first end region of the column member.

[0019] Alternatively or in addition to any of the above embodiments, the tissue retraction device further comprises a second tissue engaging member, and wherein the resilient member extends between the first tissue engaging member and the second tissue engaging member.

[0020] Alternatively or in addition to any of the above embodiments, the tissue retraction device further comprises a tubular support member including a lumen extending therein, and wherein at least a portion of the resilient member extends within the lumen of the support member.

[0021] Alternatively or in addition to any of the embodiments above, wherein the support member is located between the first tissue engaging member and the second tissue engaging member.

[0022] Another type of tissue retraction device includes:

[0023] A first tissue clamp and a second tissue clamp, the first tissue clamp is coupled to the elastic member via a first coupling assembly, the second tissue clamp is coupled to the elastic member via a second coupling assembly, and wherein the first coupling assembly and the second coupling assembly each comprise:

[0024] a coupler body having a first end region; and

[0025] Compression member;

[0026] wherein the first end region of each of the coupler bodies is configured to extend into a portion of the lumen of the resilient member;

[0027] Each of the compression members is designed to compress the elastic member onto each of the connector bodies so that the elastic member securely engages each of the connector bodies.

[0028] Alternatively or in addition to any of the above embodiments, wherein the first end region of each of the coupling bodies includes a channel extending around a circumference thereof.

[0029] Alternatively or in addition to any of the above embodiments, wherein each of the compression members is designed to compress the resilient member within at least a portion of the channel of each of the coupling bodies.

[0030] Methods of dissection include:

[0031] A tissue retractor is advanced to the target site, the tissue retractor comprising:

[0032] A first tissue engaging member coupled to the elastic member via a coupling assembly, the coupling assembly comprising:

[0033] a first coupling body having a first end region; and

[0034] a first compression member;

[0035] wherein the first end region of the first coupler body is configured to extend into a portion of the lumen of the resilient member;

[0036] wherein the compression member is designed to compress the resilient member against the first coupling body so that the resilient member securely engages the coupling body;

[0037] manipulating the first tissue engaging member between a first configuration and a second open configuration; and

[0038] A first tissue engaging member is attached to the target site.

[0039] The above summary of some embodiments is not intended to describe each disclosed embodiment or every implementation of the present disclosure. The following figures and detailed description more particularly exemplify these embodiments. BRIEF DESCRIPTION OF THE DRAWINGS

[0041] The present invention may be more fully understood upon consideration of the following detailed description taken in conjunction with the accompanying drawings, in which:

[0042] Figure 1 is a partial side cross-sectional view of an example tissue retraction device positioned within a body cavity;

[0043] Figure 2 A stereogram of a retractor device for example organization;

[0044] Figure 3 for Figure 2 An exploded view of an example tissue retraction device is shown;

[0045] Figure 4 An example tissue engaging member is shown;

[0046] Figure 5 A three-dimensional view of a tissue retraction device for another example;

[0047] Figure 6 for Figure 5 An exploded view of an example tissue retraction device is shown;

[0048] Figures 7 to 9 An example tissue engaging member is shown;

[0049] Figures 10 to 14 Methods for deploying and attaching example tissue retraction devices are shown.

[0050] Although the present disclosure may be modified into various modifications and alternatives, the details thereof have been shown in the drawings by way of example and will be described in detail. However, it should be understood that it is not intended to limit the present disclosure to the specific embodiments described. On the contrary, it is intended to cover all modifications, equivalents and alternative forms that fall within the spirit and scope of the present disclosure. DETAILED DESCRIPTION

[0051] With respect to the following defined terms, these definitions shall apply, unless a different definition is given in the claims or elsewhere in this specification.

[0052] All numerical values ​​are assumed to be modified by the term "about" herein, whether or not explicitly indicated. The term "about" generally refers to a numerical range that one skilled in the art considers to be equivalent to the recited value (i.e., having the same function or result). In many instances, the term "about" may include numerical values ​​rounded to the nearest significant figure.

[0053] The recitation of numerical ranges by endpoints includes all numbers within that range (eg, 1 to 5 includes 1, 1.5, 2, 2.75, 3, 3.80, 4, and 5).

[0054] As used in this specification and the appended claims, the singular forms "a," "an," and "the" include plural referents unless the context clearly dictates otherwise. As used in this specification and the appended claims, the term "or" is generally employed in its sense including "and / or" unless the content clearly dictates otherwise.

[0055] It should be noted that references in the specification to "one embodiment", "some embodiments", "other embodiments", etc. indicate that the described embodiments may include one or more specific features, structures and / or characteristics. However, such statements do not necessarily mean that all embodiments include the specific features, structures and / or characteristics. In addition, when specific features, structures and / or characteristics are described in conjunction with one embodiment, it should be understood that such features, structures and / or characteristics may also be used in conjunction with other embodiments, whether or not explicitly described, unless explicitly indicated to the contrary.

[0056] The following detailed description should be read with reference to the drawings, in which similar elements in different drawings are numbered the same. The drawings, which are not necessarily drawn to scale, illustrate illustrative embodiments and are not intended to limit the scope of the invention.

[0057] A variety of medical procedures (including endovascular procedures, procedures along the digestive and / or bile ducts, chest procedures, etc.) utilize medical devices to access tissue within the body that is intended to be removed (e.g., "target tissue"). For example, in some current medical procedures (e.g., endoscopic submucosal dissection (ESD), peroral endoscopic incision (POEM), cholecystectomy, video-assisted thoracoscopic surgery (VATS)), a doctor may utilize an endoscope or similar medical device to access and remove cancerous lesions. In addition, as part of the procedure, a doctor may utilize an endoscope that is able to access the target tissue site while also allowing a cutting device to be deployed through to remove the target tissue. In addition, in some cases, an endoscope may incorporate features that help the doctor visualize and perform the tissue dissection process. For example, some endoscopes may include lights and / or cameras designed to illuminate the body cavity because the endoscope needs to be navigated and positioned adjacent to the target tissue site. In addition, some endoscopes may also include a lumen (e.g., a working channel) through which a cutting member or other accessory medical device may be deployed and utilized.

[0058] While physicians are becoming increasingly adept at extracting cancerous lesions from within the body (e.g., within the digestive tract, within the abdominal cavity, within the chest cavity, etc.), extraction methods continue to be inefficient and time consuming. For example, in some cases, poor visualization of the tissue dissection process can result in prolonged tissue dissection surgeries. In another example, the actual tissue that the physician is attempting to dissect may itself block the path of the tools that the physician is using during the procedure. Therefore, in some cases, it may be desirable to utilize a medical device that helps improve visualization of the target tissue while also alleviating obstruction from the dissection tools used by the physician. Therefore, in some cases, it may be desirable to utilize a tissue retractor that lifts and retracts an area of ​​tissue to be dissected by the physician. Disclosed herein are medical devices, such as tissue retractors and delivery systems, that are designed to lift and retract target tissue.

[0059] Figure 1 1 is a partial side cross-sectional view of an example tissue retraction delivery system 10 including a distal portion 12 and a proximal portion 14 . Figure 1 The distal portion 12 of the tissue retraction system 10 is shown positioned within an example body cavity 16. In addition, Figure 1 As shown, the proximal portion 14 of the tissue retraction system 10 can extend out of the body cavity 16 to a location outside the body. Figure 1 As shown, the tissue retraction system may include a tissue retraction device 22. In addition, the tissue retraction system 10 may include a delivery catheter 26. The delivery catheter 26 may be constructed of a semi-rigid or compliant material, such as a thermoplastic elastomer, silicone rubber, nylon, polyurethane, polyethylene terephthalate (PET), latex, or the like. The delivery catheter 26 may have a distal end region 28 and a proximal end region 30. In addition, a lumen 32 may extend through the delivery catheter 26 from the proximal end region 30 to the distal end region 28. As shown, the tissue retraction device 22 may be positioned along the distal end region 28 and may be located within the lumen 32 of the delivery catheter 26.

[0060] also, Figure 1 As shown, the delivery catheter 26 (including the tissue retraction device 22) can be extended through the example medical device 18. As discussed above, in Figure 1 In the embodiment, the medical device 18 may be in the form of an endoscope, a laparoscope, a needle, a catheter, a guide tube, etc. The medical device 18 may include a distal portion 23 and a proximal portion 25. In addition, Figure 1 As shown, the distal portion 23 of the medical device 18 may be advanced within a portion of the body cavity 16 to a position adjacent to a target tissue 50, such as a lesion, while the proximal portion 25 of the medical device 18 may be extended away from the body cavity 16 to a position outside the body.

[0061] The medical device 18 may include a lumen 21 extending from a proximal portion 25 to a distal portion 23 of the medical device 18. In some examples, the lumen 21 may be referred to as a "working channel" of the medical device 18. The lumen 21 may be designed to allow a variety of medical devices to pass through. For example, a physician may pass or exchange a variety of medical devices through the working channel 21 during a given medical procedure. For example, Figure 1 As shown, the delivery catheter 26 (including the tissue retraction device 22) can extend through the lumen 21 of the medical device 18. In other words, Figure 1 As shown, a physician can insert the distal end 28 of the delivery catheter 26 into the proximal portion 25 of the medical device 18 (which is outside the body), advance the delivery catheter 26 through the lumen 21, and the distal end 28 of the delivery catheter can thereby ultimately extend away from the distal portion 23 of the medical device 18 to a position adjacent to the target tissue 50.

[0062] The proximal end 30 of the delivery catheter 26 may include a control member 42. The control member 42 may be used as a grip to control translation of the delivery catheter 26. Additionally, the control member 42 may also allow a user to rotate the delivery catheter 26. As will be described in greater detail below, the control member 42 may be used by a physician to advance the distal end 28 of the delivery catheter 26 to a position adjacent to the target tissue 50 prior to deploying the tissue retraction device 22 from the distal end 28 of the delivery catheter 26.

[0063] In some examples, the medical device 18 may include additional features. For example, Figure 1 The illustrated medical device 18 may include accessory features 20 (eg, a light, a camera, etc.) located on a distal portion 23 of the medical device 18. Additionally, other medical devices 18 having additional features may be used in conjunction with the tissue retraction system 10.

[0064] like Figure 1 As shown, in some examples, the tissue retraction system 10 can include a manipulation device 34 ("manipulator") designed to advance (e.g., push, deploy, etc.) the tissue retraction device 22 out of the distal end 28 of the delivery catheter 26. As will be described in more detail below, once the manipulator 34 has advanced the tissue retraction device 22 out of the delivery catheter 26, the manipulator 34 can also be used to position the tissue retraction device 22 within the body cavity 16 and / or manipulate the tissue retraction device 22 within the body cavity 16.

[0065] like Figure 1 As shown, the manipulator 34 can extend within the lumen 32 of the delivery catheter 26. In other words, Figure 1As shown, the distal end 38 of the manipulator 34 can extend from the proximal end 30 of the delivery catheter 26 (which is outside the body) through the lumen 32 of the delivery catheter 26, whereby the distal end 38 of the manipulator 34 can be positioned adjacent the proximal end of the tissue retraction device 22.

[0066] The proximal end 40 of the manipulator 34 may include a handle member 44. The handle member 44 may include one or more finger grips 45 that allow a user to grasp and thereby advance (e.g., translate) the distal end 38 of the manipulator within the lumen 32 of the delivery catheter 26. In other words, by grasping and manipulating the handle 44, the user may be able to translate the manipulator 34 along the longitudinal axis of the delivery catheter 26. Figure 1 The handle designs shown are illustrative. Other handle designs are also contemplated. For example, handle designs including different clamp structures, ergonomic features, etc. that can be used with the tissue retraction system 10 (and its components) are also contemplated.

[0067] The distal end 38 of the manipulator 34 may include a gripping member 39 (e.g., forceps, claws, etc.). When located within the lumen 32 of the delivery catheter 26, the gripping member 39 may be in a closed position (e.g., the claws of the gripping member 39 may be closed and in contact with each other). In addition, the handle member 44 may be designed to control the opening and / or closing of the gripping member 39. In other words, when the gripping member 39 is advanced to a position outside the lumen 32 of the delivery catheter 26, the user may manipulate the handle member 44 to open and / or close the gripping member 39.

[0068] As described above, the manipulator 34 can be used to deploy the tissue retraction device 22 away from the distal end 28 of the delivery catheter 26. In particular, it can be appreciated that when positioned adjacent to the target tissue 50, the user can advance the manipulator 34 in the proximal-to-distal direction within the lumen 32 of the delivery catheter 26 so that the grasping member 39 can contact the proximal end of the tissue retraction device 22 and push the proximal end away from the distal end 28 of the delivery catheter 26.

[0069] In at least some examples contemplated herein, the manipulator 34 and the tissue retraction device 22 may be positioned within the delivery catheter 26 prior to advancing the delivery catheter 26 through the lumen 21 of the medical device 18, such as Figure 1In other words, in some examples, both the manipulator 34 and the tissue retraction device 22 may be "preloaded" into the delivery catheter 26 prior to being inserted and advanced through the working channel 21 of the medical device 18 to a position adjacent to the target tissue 50. However, in other examples, only the tissue retraction device 22 may be preloaded into the delivery catheter 26 and may be advanced within the lumen 21 of the medical device 18 to a position adjacent to the target tissue 50, after which the manipulator 34 may be separately inserted into the lumen 21 of the medical device 18 and may be advanced to a position where the grasping member 39 is adjacent to and / or in contact with the proximal end of the tissue retraction device 22.

[0070] As can be appreciated from the above discussion, the tissue retraction system 10 can be designed so that the delivery catheter 26 and the manipulator 34 can move relative to each other (e.g., translate, rotate, etc.). For example, once the distal end 28 of the delivery catheter 26 is positioned adjacent to the target tissue 50 (where the manipulator 34 is positioned adjacent to the distal end of the tissue retraction device 22), the user can grasp both the control member 42 and the handle member 44. This can allow the user to maintain the distal end 28 of the delivery catheter 26 in a fixed position while advancing the manipulator 34 in the distal direction so that the grasping member 39 moves distally relative to the distal end 28 of the delivery catheter 26. It can be appreciated that this relative movement can push the tissue retraction device 22 out of the distal end 28 of the delivery catheter 26.

[0071] In other examples, it will be appreciated that, instead of the user advancing the manipulator 34 in the distal direction to deploy the tissue retraction device 22, the user may alternatively retract the delivery catheter 26 while maintaining the manipulator 34 in a fixed position. Retraction of the delivery catheter 26 may "expose" the tissue retraction device 22, thereby releasing it from the lumen 32 of the delivery catheter 26.

[0072] Figure 2 An example tissue retraction device 22 is shown. The tissue retraction device 22 may include one or more engagement members 51 (eg, clamps, clasps, fasteners, clamps, etc.). For example, Figure 2 As shown, the tissue retraction device 22 may include a first engagement member 52a and a second engagement member 52b. The first engagement member 52a may include a first end 54a and a second end 56a. The first end 54a may include one or more claws 61a (e.g., an end effector). The claws 61a may be designed so that they move relative to each other. Figure 2 Also shown, the second end 56a of the first engagement member 52a can include a spring 60a. It will be appreciated that the spring 60a can be designed to provide a compressive force that translates through the body of the first engagement member 52a to the jaw member 61a, thereby biasing the jaw member 61a in a closed position (e.g., a position in which the jaw members 61a contact each other).

[0073] In some examples, the ends of the jaw members 61a may not necessarily contact each other when in the closed position. The jaw members 61a may be spaced apart from each other when in the closed position. When contacting tissue, spacing the jaw members 61a in the closed position from each other may allow for the generation of additional compressive force. This additional compressive force may be referred to as "preload". The preload force may range from about 5g of force to about 200g of force, or from about 15g of force to about 40g of force.

[0074] It is understood that the engagement member 51 described in the examples disclosed herein is illustrative. In other words, it is contemplated that the engagement member 51 described herein may include alternative design arrangements, features, geometries, etc. without departing from the scope of the examples contemplated herein. For example, it is contemplated that the spring 60a of the first engagement member 52a may be located between the first end 54a and the second end 56a of the first engagement member 52a. In addition, it is contemplated that the jaws (e.g., end effectors) may have a variety of different shapes and / or geometries without departing from the scope of the examples contemplated herein. Other variations are also contemplated.

[0075] Figure 2 It is also shown that the first engagement member 52a may also include one or more clamping members 58a. For example, Figure 2 61a and the clamping member 58a can be formed of the same material as the jaw member 61a. In other words, the jaw 61a and the clamping member 58a can be formed as a single component. For example, the jaw 61a (e.g., the end effector) and the clamping member can be metal injection molded (MIM), conventionally machined, stamped, additively manufactured, etc. However, this is not intended to be limiting. Instead, it is contemplated that the jaw 61a and the clamping member 58a can be formed as two separate components that are attached (e.g., welded, glued, press-fitted, etc.) together to form a Figure 2 In addition, Figure 2 As shown, in some examples, a portion of the clamping member 58a can be designed to engage, cooperate, interconnect, attach, etc. with the spring 60a. For example, Figure 2 A portion of a spring 60a is shown extending into a channel of the clamping member 58a. The spring 60a may be rigidly attached (eg, welded, attached, etc.) to the clamping member 58a.

[0076] As described above, after the tissue retraction device 22 has been deployed out of the distal end 28 of the delivery catheter 26, the manipulator 34 can be used to position and / or attach the tissue retraction device 22 to the target tissue 50 within the body cavity 16. It can be appreciated that the clamping member 58a can be designed to engage the grasping member 39 (which is located on the distal end 38 of the manipulator 34). In other words, the clamping member 58a can provide an interface that the grasping member 39 can engage, attach, clamp, grasp, capture, etc. with the first engagement member 52a.

[0077] Furthermore, the gripping members 58a may be designed such that they allow the manipulator 34 to effectively acquire, position (and / or reposition) and open / close the jaws 61a of the first engagement member 52a. Figure 2 The clamping member 58a is shown as being located between the first end 54a and / or the second end 56a of the first engaging member 52a, but it is contemplated that the clamping member 58a may be positioned along other portions of the first engaging member 52a. For example, the clamping member 58a may be located on the first end 54a and / or the second end 56a of the first engaging member 52a.

[0078] As discussed above, the tissue retraction device 20 may include more than one tissue engaging member (eg, another engaging member in addition to the first tissue engaging member 52a described above). Figure 2 2, the tissue retraction device 22 may include a second tissue engaging member 52b. The second tissue engaging member 52b may be similar in form and function to the first tissue engaging member 52a. For example, the second tissue engaging member 52b may include a first end 54b and a second end 56b. The first end 54b may include one or more claws 61b. The claws 61b may be designed so that they move relative to each other. Figure 2 It is also shown that the second end 56b of the second tissue engagement member 52b may include a spring 60b. It is understood that the spring 60b may be designed to provide a compressive force that translates through the body of the second engagement member 52b to the claw member 61b, thereby biasing the claw member 61b in a closed position (e.g., a position in which the claw members 61b contact each other). It is understood that the second engagement member 52b described in the examples disclosed herein is schematic. In other words, it is contemplated that the second engagement member 52b described herein may include alternative design arrangements, features, geometric shapes, etc. without departing from the scope of the examples contemplated herein. For example, it is contemplated that the spring 60b of the second engagement member 52b may be located between the first end 54b and the second end 56b of the second engagement member 52b. Other variations are also contemplated.

[0079] Figure 2 It is also shown that the first engagement member 52a may also include one or more clamping members 58b. For example, Figure 2 61a and the clamping member 58a may be formed as two separate parts that are attached (e.g., welded, glued, press-fitted, etc.) together to form a single piece. Figure 2 In addition, Figure 2 As shown, in some examples, a portion of the clamping member 58b can be designed to engage, cooperate, interconnect, attach, etc. with the spring 60b. For example, Figure 2 A portion of a spring 60b is shown extending into a channel of the clamping member 58b. The spring 60b may be rigidly attached (eg, welded, attached, etc.) to the clamping member 58b.

[0080] Figure 2 Also shown, the tissue retraction device 22 may include a tether 62 (e.g., Figure 2 The tether 62 is connected to the first engagement member 52a, the second engagement member 52b, or both the first engagement member 52a and the second engagement member 52b. The tether 62 may be a tubular member having a lumen extending therein. The tether 62 may be referred to as an elastic member, a band, a thick rope, a thin rope, a belt, a strip, a strand, etc. The tether 62 may include a variety of cross-sectional geometries. For example, the tether may be circular, rectangular, triangular, etc. In addition, the tether 52 may be bioabsorbable.

[0081] In at least some examples, the tether 62 can be elastomeric. In some examples, the tether 62 can be composed of an elastomeric material, such as latex, Rubber, EPDM, silicone rubber, chloroprene, polychloroprene (e.g. ), polyolefins, thermoplastic elastomers, polyisoprene, etc.

[0082] The tether member 62 is extendable from a first unextended (e.g., relaxed) position to a second extended position. It will be appreciated that when the tissue retraction device 22 is in the extended position, the tissue retraction device is in tension and therefore includes a retraction force that pulls the first engagement member 52a toward the second engagement member 52b along the longitudinal axis of the tissue retraction device 22.

[0083] As described above, the tissue retractor 22 may be in an unstretched, relaxed state within the distal end 28 of the delivery catheter 26 prior to deployment from the delivery catheter. Additionally, proper alignment of the tissue retractor 22 within the delivery catheter 26 (prior to deployment) must be maintained to ensure that the tissue retractor 22 is effectively disposed within the body cavity 16. For example, it is important to prevent the tissue retractor 22 from folding and / or twisting upon itself (e.g., folding back upon itself) while being advanced and / or manipulated within the distal end 28 of the delivery catheter 26.

[0084] Figure 2 As shown, in some examples, the tissue retraction device 22 may include a support member 64. In some cases, the support member 64 may be a tubular member having a lumen 53 extending therein. For example, Figure 2The illustrated tissue retraction device 22 shows a tether member 62 extending within the lumen 53 of the support member 64. In addition, Figure 2 As shown, the support member 64 can extend between (eg, be located between) the first tissue engaging member 52a and the second tissue engaging member 52b. Figure 2 The support member 64 is shown as a tubular member, but other cross-sectional shapes of the support member 64 are also contemplated. For example, the cross-sectional shape of the support member 64 can be rectangular, triangular, oval, square, etc. In addition, it is contemplated that the tissue retraction device 22 can include more than one support member 64. For example, the tissue retraction device 22 can include 1, 2, 3, 4, or more support members.

[0085] As described above, Figure 2 As shown, the support member 64 can be disposed along the tether member 62. For example, in some examples, the tether member 62 can extend through the lumen 53 of the support member 64. In at least some examples, the support member 64 can allow the tether 62 to be compressed in the lumen 53 of the support member 64. Thus, the diameter of the lumen 53 of the support member 64 can be wide enough to allow the tether 62 to curl upon itself to be "stored" within the lumen of the support member 64. Allowing the tether 62 to be stored within the lumen of the support member 64 can prevent the tether 62 from being entangled with the first engagement member 52a.

[0086] In addition, in at least some examples described herein, support member 64 can include sufficient stiffness and breaking strength to withstand compression during packaging and storage prior to device delivery. Possible materials include polypropylene, PET, thermoplastic elastomer (TPE), polyethylene (PE), or high-density polyethylene (HDPE), such as Celanese GUR HOSTALLOY 731. Figure 2 Also shown, tether 62 can be coupled to tissue engaging member 52a via coupler body 36a and connecting member 46a. As will be described in greater detail below, connecting member 46a can include post member 48a and attachment member 47a. Figure 2 It is also shown that the proximal end of the coupler body 36a can extend within the lumen 53 of the tether member 62. The compression member 49a can be located on top of both the proximal end of the coupler body 36a and the tether 62, whereby the compression member 49a can compress the tether 62 radially on the proximal end of the coupler body 36a with sufficient force to securely attach the tether 62 to the coupler body 36a. In other words, the tether 62 can be attached to the coupler body 36a by "sandwiching" the tether 62 between the coupler body 36a and the compression member 49a. The compression member 49a can include a variety of different structures without departing from the scope of the examples contemplated herein. For example, the compression member 49a can include a compression ring, a suture, a clamp, a rope, a knot, a crimped ultrasonic weld, a ring, etc.

[0087] As will be described in more detail below, the post member 48a can extend through the hole 57a formed in the coupler body 36a, thereby preventing the proximal end of the post member 48a from being pulled through the hole 57a. Figure 3 It will be shown that the post member 48a can include a proximal end designed to allow the post member 48a to rotate while preventing the post member 48a from separating from the coupler body 36a.

[0088] also, Figure 2 As shown, the distal end of the column member 48a can be attached to the attachment member 47a. For example, Figure 2 As shown, the attachment member 47a can include a curved portion (eg, a generally C-shaped portion) that can resemble a partial ring. Figure 2 It is also shown that the attachment member 47a can extend through the annular portion of the spring 60a, thereby coupling the attachment member 47a to the tissue engaging member 52a via the spring 60a. Figure 2 4, the attachment member 47a can be attached to the distal end of the column member 48a, thereby connecting the attachment member 47a to the connector body 36a via the column member 48a. Therefore, it can be understood that the connecting member 46a (which includes the attachment member 47a and the column member 48a) together with the connector body 36a and the compression member 49a can connect the tissue engaging member 52a to the tether member 62.

[0089] It should be noted that the above description can also be applied to coupling the second tissue engaging member 52b to the tether 62. For example, the second tissue engaging member 52b can be coupled to the connector body 36b via the connecting member 46b. Similar to the above description, the connecting member 46b can include an attachment member 47b and a column member 48b. The attachment member 47b can be coupled to the spring 60b. In addition, the attachment member 47b can be attached to the column member 48b. The column member 48b can extend through the hole 57b ( Figure 2 In addition, the tether 62 can be attached to the coupling body 36b via radial compression of the compression ring 49b onto the coupling body 36b.

[0090] Figure 3 2 is an exploded view of one end portion of the tissue retraction device 22 described above. Figure 3 The individual components used to couple the tethering member 62 to the tissue engaging member 52a are shown, as described above. For example, Figure 3 A tissue engaging member 52a is shown including a spring 60a. Figure 3 As shown, the spring 60a may include a coil portion through which the attachment member 47a may extend. Figure 3As further shown, the attachment member 47a may include a curved portion 75a that may resemble a partial ring. Additionally, the attachment member 47a may include an opening 67a that may allow for insertion attachment to the coil portion of the spring 60a for assembly purposes.

[0091] Figure 3 Both the compression member 49a and the connector body 36a are also shown. In some examples, the connector body 36a may include a channel 55a extending circumferentially around the connector body 36a. The channel 55a may be designed to fit the compression member 49a. For example, the width, depth, and / or profile of the channel 55a may fit the width, thickness, and / or profile of the compression member 49a. As described above, the tether 62 may be radially compressed between the connector body 36a and the compression member 49a to securely attach the tether 62 to the connector body 36a.

[0092] also, Figure 3 As shown, the coupling body 36a may include a hole 57a through which the post member 48a may extend. The diameter of the hole 57a is Figure 3 Marked with "X 1” .also, Figure 3 As shown, the column member 48a may include a first end region 59a and a second end region 63a. The second end region 63a of the column member 48a may include a tapered portion. The tapered portion may include a diameter X greater than the diameter of the hole 57a. 1 The diameter "Y 1 ". It will be appreciated that the column member 48a may include a length that allows the column member 48a to extend through the hole 57a, whereby the first end region 59a may be securely attached to the attachment member 47a. For example, the first end region 59a of the column member 48a may be welded to the attachment member 47a. It will also be appreciated that after the column member 48a extends through the connector body 36a and is attached to the attachment member 47a, the connector body 36a may be coupled to the attached combination of the attachment member 47a and the column member 48a.

[0093] Figure 3 It is also shown that the lumen 53 of the tether 62 can be sized so that it can be located on a portion of the coupler body 36a. For example, the tether 62 can be located on top of the proximal portion of the coupler body 36a so that a portion of the tether 62 can be positioned along the channel 55a. As described above, the compression member 49a can be located on top of the tether 62 so that it radially compresses the tether 62 on the coupler body 36a, thereby attaching the tether 62 to the coupler body 36a.

[0094] Figure 4An example tissue engaging member 52a is shown. As discussed above, tissue engaging member 52a can include jaw members 61a, clamping members 58a, and coil spring 60a. Figure 4 Also shown, the spring portion 60a can include one or more rods 68a that engage (e.g., fit) a recessed portion 69a located in the clamping member 58a. It is contemplated that the rods 68a can be attached to the recessed portion 69a using a variety of techniques. For example, the rods 68a can be welded, press-fitted, glued, etc., into the recessed portion 69a.

[0095] also, Figure 4 As shown, the jaws 61a can each include one or more teeth 65. It will be appreciated that the teeth 65 can include a variety of different shapes oriented in a variety of different configurations. Figure 4 Each of the jaws 61a shown may include two teeth 65, wherein the teeth 65 of one jaw 61a may mirror the teeth 65 of the other jaw 61a. In other words, the teeth 65 of the "top" jaw may be aligned with the teeth 65 of the "bottom" jaw. In addition, Figure 4 As shown, the specific arrangement of the teeth results in a hole 66 located in the central region of the teeth. In addition, it is understood that the claw 61a can be designed to exhibit an inclination facing the coil portion 60a of the first engagement member 52a. For example, Figure 4 As shown, the "end face" of each claw 61a defining each of the teeth 65 may be at an angle (at Figure 4 The inner surface of the prism (marked as “θ”) is tilted inwards. Figure 4 As shown, this angle can create a sharp point that can more actively engage tissue. The oblique direction enhances tissue engagement by preventing the captured tissue from escaping.

[0096] Figure 5 Another example tissue retraction device 122 is shown. The tissue retraction device 122 may be similar in form and function to the tissue retraction device 22 described above. For example, the tissue retraction device may include a first tissue engaging member 52a (including a claw 61a, a clamping member 58a, and a spring 60a) and a second tissue engaging member 52b (including a claw 61b, a clamping member 58b, and a spring 60b). In addition, the first tissue engaging member 52a may be coupled to the tether 62 via a connecting member 146a and a connector body 136a. Similarly, the second tissue engaging member 52b may be coupled to the tether 62 via a connecting member 146b and a connector body 136b. As discussed above, the tissue retraction device 122 may include a support member 64 disposed along the tether 62.

[0097] Figure 6 FIG. 1 is an exploded view of one end of the tissue retraction device 122 described above. Figure 3 As described, Figure 6A tether 62 is shown for coupling to Figure 5 Individual components of the tissue engaging member 52a are shown. For example, Figure 6 A tissue engaging member 52a is shown including a clamping member 58a and a spring 60a. Figure 6 A tether 62 is shown including a lumen 53 extending therein. Figure 6 Also shown are the individual components of the connecting member 146a which, in conjunction with the coupler body 136a, couple the tissue engaging member 52a to the tether 62.

[0098] To this end, the connecting member 146a ( Figure 5 148a, a first fitting 167a, and a second fitting 168a. The post member may include a first end 159a and a second end 163a. ​​It is understood that the first fitting 167a and the second fitting 168a may be designed to cooperate with each other. In other words, the first fitting 167a and the second fitting 168a may be two separate parts that "snap" together to form a single part. In addition, it is also understood that the first fitting 167a and the second fitting 168a may include one or more "gaps" or "protrusions" designed to capture both the coil portion of the spring 60a and the protrusion 170a, which is located on the first end 159a of the post member 148a.

[0099] For example, the protrusion 170a may be designed to engage the void 171a, half of the void 171a formed in the first fitting 167a and half of the void 171a formed in the second fitting 168a (note that the half of the void 171a formed in the first fitting 167a is formed in the second fitting 168a). Figure 6 In addition, Figure 6 A first protrusion 172a is shown extending outwardly from the second fitting 168a, which is designed to mate with a second protrusion 173a extending outwardly from the first fitting 167a. As discussed above, the first protrusion 172a and the second protrusion 173a can be designed to interlock with each other through an opening 174a formed in the spring portion 60a, thereby capturing the spring portion 60a between the first fitting 167a and the second fitting 168a.

[0100] also, Figure 6 As shown, the coupling body 36a may include a hole 157a through which the post member 148a may extend. The diameter of the hole 157a is Figure 6 Marked with "X 2 ".also, Figure 6As shown, the column member 148a may include a first end region 159a and a second end region 163a. ​​The second end region 163a of the column member 148a may include an enlarged portion. The enlarged portion may include a diameter X that is larger than the hole 157a. 2 The diameter "Y 2 ”. It can be appreciated that the post member 148a may include a length that allows the post member 148a to extend through the hole 157a, whereby the protrusion 170a of the first end region 159a may be securely attached to the gap 171a formed by the first fitting 167a and the second fitting 168a. It can also be appreciated that after the post member 148a extends through the connector body 136a and is attached to the first fitting 167a and the second fitting 168a, the connector body 136a may be coupled to the attached combination of the first fitting 167a, the second fitting 168a, and the post member 148a.

[0101] Figure 6 It is also shown that the lumen 53 of the tether 62 can be sized so that it can be located on a portion of the coupler body 136a. For example, the tether 62 can be located on top of the proximal portion of the coupler body 136a so that a portion of the tether 62 can be positioned along the channel 155a (extending circumferentially around the coupler body 136a). As described above, a compression member (e.g., a compression ring, suture, ribbon, clamp, etc.) can be located on top of the tether 62 so that it radially compresses the tether 62 on the coupler body 136a, thereby attaching the tether 62 to the coupler body 136a.

[0102] Figures 7 to 9 Different example tissue joining members are shown. Without departing from the scope of the examples contemplated herein, Figures 7 to 9 The tissue engaging members shown may vary in size, shape, geometry, etc. For example, the specific shape and geometry of the end effectors (e.g., jaws, teeth, clamping members, etc.) disclosed herein may be different. However, it is contemplated that any of the features disclosed with respect to the example tissue engaging members may be compatible with any other tissue engaging members disclosed herein.

[0103] Figure 7 Another example tissue engaging member 251 is shown. The tissue engaging member 251 can be similar in form and function to the tissue engaging member 51 described above. For example, the tissue engaging member 251 can include a claw 261, a clamping member 258, and a spring 260. In addition, Figure 7 As shown, each of the claws 261 may include a single flat tooth 265, wherein each tooth 265 faces another. Figure 4As depicted by the illustrated tissue engaging member 52a, each tooth 265 can be angled such that it is angled toward the coil portion 260. The angled orientation enhances tissue engagement by preventing escape of captured tissue.

[0104] Figure 8 Another example tissue engaging member 351 is shown. The tissue engaging member 351 can be similar in form and function to the other tissue engaging members described above. For example, the tissue engaging member 351 can include a claw 361, a clamping member 358, and a spring 360. In addition, Figure 8 Shown, Figure 8 The "top" jaw 361 may include a first tooth 365 and a second tooth 375, wherein the first tooth 365 is wider than the second tooth 375. In addition, the first tooth 365 may be spaced apart from the second tooth 375 to form a gap 366 between the first tooth 365 and the second tooth 375. Similarly, Figure 8 The "bottom" jaw 361 of the embodiment may include a first tooth 365 and a second tooth 375, wherein the first tooth 365 is wider than the second tooth 375. In addition, the first tooth 365 may be spaced apart from the second tooth 375 to form a gap 366 between the first tooth 365 and the second tooth 375. In addition, it is understood that the teeth may be arranged such that the first teeth 365 of the top row are aligned with the gaps 366 of the bottom row, while the first teeth 365 of the bottom row are aligned with the gaps 366 of the top row. In other words, the teeth of the top row are designed to interdigitate with the teeth of the bottom row.

[0105] Furthermore, it will be appreciated that each of the first teeth 365 and each of the second teeth 375 may be angled such that they are angled toward the coil portion 360 (as described above with respect to other tissue engaging members). The angled orientation enhances tissue engagement by preventing escape of captured tissue.

[0106] Fig. 9 Another example tissue engaging member 451 is shown. The tissue engaging member 451 can be similar in form and function to the other tissue engaging members described above. For example, the tissue engaging member 451 can include a claw 461, a clamping member 458, and a spring 460. In addition, Fig. 9 As shown, the jaws 461 can each include one or more teeth 465. It can be appreciated that the teeth 465 can include a variety of different shapes oriented in a variety of different configurations. Fig. 9 Each of the jaws 461 shown may include two teeth 465, wherein the teeth 465 of one jaw 461 may mirror the teeth 465 of the other jaw 461. In other words, the teeth 465 of the "top" jaw may be aligned with the teeth 465 of the "bottom" jaw. Fig. 9 It is shown that the specific arrangement of teeth 465 results in a hole 466 located in a central region of the tooth 465 .

[0107] Furthermore, as described above with respect to other tissue engaging members, each tooth 465 can be canted such that it is angled toward coil portion 460. The canted orientation enhances tissue engagement by preventing escape of captured tissue.

[0108] Figures 10 to 14 A series of steps for deploying and utilizing the tissue retraction system 10 described above are shown. The tissue retraction device 22 can be used to lift and reposition the target tissue that has been removed by the clinician. As will be more apparent from the following illustrations, as the clinician cuts away the target tissue, the tissue retraction device can lift and reposition the target tissue, thereby providing the clinician with an unobstructed view of the ongoing procedure.

[0109] Fig.10 The first step of using the tissue retraction system 10 in a peeling procedure is shown. Fig.10 As shown, the clinician may first advance the manipulator 34 in a proximal to distal direction (relative to the distal end 28 of the delivery catheter 26). This forward movement of the manipulator will force the manipulator's grasping member 39 to push the tissue retraction device 22 forward and out of the distal end 28 of the delivery catheter 26. Fig.10 The tissue retraction device 22 is shown having been advanced out of the distal end 28 of the delivery catheter 26, thereby being positioned adjacent to the target tissue 50 (eg, a cancerous lesion).

[0110] Fig.11 An example second step of using tissue retraction system 10 in a dissection procedure is shown. Fig.11 As shown, the clinician can manipulate the distal end 38 of the manipulator 34 to grasp the first engagement member 52a (for clarity, the grasping member 39 is shown in Fig.11 , a closed configuration. It will be appreciated that the grasping member 39 can be opened to grasp the first engagement member 52a). For example, the clinician can manipulate the handle 44 of the tissue retraction system 10 to open the jaws of the grasping member 39. Once opened, the jaws of the grasping member can engage the clamping member 58a of the first engagement member 52a. After engaging the clamping member 58a, the clinician can close the jaws of the grasping member 39, thereby opening the jaws 61a of the first engagement member 52a. Using the grasping member 39, the clinician can then position the jaws 61a on the surface of the target tissue 50. By releasing the grasper 39 from the clamping member 58b, the jaws 61a of the first engagement member 52a can be closed and the jaws 61a (and, by extension, the first engagement member 52a) are attached to the surface of the target tissue 50.

[0111] Fig.12 An example third step of using tissue retraction system 10 in a dissection procedure is shown. Fig.12As shown, the clinician can manipulate the distal end 38 of the manipulator 34 to grasp the second engagement member 52b (for clarity, the grasper 39 is shown in the Fig.12 ). It will be appreciated that the grasper 39 can be opened to grasp the second engagement member 52b. For example, the clinician can manipulate the handle 44 (described above) of the tissue retraction system 10 to open the jaws of the grasper 39. Once opened, the jaws of the grasper can engage the clamping member 58b of the second engagement member 52b. After engaging the clamping member 58b, the clinician can close the jaws of the grasper 39, thereby opening the jaws 61b of the second engagement member 52b. The clinician can then pull on the second engagement member 52b to cause the tissue retraction device 22 to grow (as described above with respect to Figure 2 and Figure 3 Once the tissue retraction device is extended to the desired length (which can be visually confirmed via the fiducial marker 66, as described above), the clinician can position the jaws 61b of the second engagement member 52b on the surface of the target tissue site 50. By releasing the gripping member 39 from the clamping member 58b, the jaws 61b of the second engagement member 52b can be closed, thereby attaching the jaws 61b (and, by extension, the second engagement member 52b) to the inner surface of the body cavity 16.

[0112] Fig.13 An example fourth step of using tissue retraction system 10 in a dissection procedure is shown. Fig.13 1, after the tissue retraction device 22 has been attached to the target tissue site 50 and attached to the inner surface of the body cavity 16 at a location spaced from the target tissue site (which places the tissue retraction device 22 in tension), the clinician can swap the manipulator 34 of the cutting tool 74. The cutting tool 74 can include a cutting member 76 positioned at the target tissue 50. In addition, the cutting tool 74 can be advanced within the working channel 21 of the medical device 18, as described above.

[0113] Fig.14 An example fifth step of using tissue retraction system 10 in a dissection procedure is shown. Fig.14 The clinician is shown performing tissue dissection by cutting a portion of the target tissue 50 using a cutting tool 74. Fig.14As will be appreciated, as the cutting tool 74 cuts a portion of the target tissue 50, the tissue retraction device 22 retracts (via the pulling of the tether members 62a / 62b), thereby lifting the dissected portion 78 of the target tissue 50 upward and away from the tissue plane being cut by the clinician. By lifting and retracting the dissected portion 78 of the target tissue 50, a clear, unobstructed view of the clinician's procedure is maintained. It is noted that the engagement members 52a / 52b of the tissue retraction system 10 can be repositioned, if desired. In other words, adjustment of tension and / or direction can be imparted to the tissue retraction system 10 as desired.

[0114] It should be noted that the features of any of the tissue retraction systems described with respect to a particular figure and / or embodiment are not limited to that particular example. Rather, it is contemplated that all features or examples disclosed with respect to a single example may be incorporated into any other example disclosed herein.

[0115] Materials that can be used for the various components and various devices of the tissue retraction system 10 disclosed herein may include those commonly associated with medical devices. To the extent that the following discussion refers to the tissue retraction system 10 for purposes of simplicity, it is not intended to limit the devices and methods described herein to only the tissue retraction system 10, as the discussion may be applicable to other similar devices disclosed herein.

[0116] The tissue retraction system 10 and / or other components of the tissue retraction system 10 can be made of metals, metal alloys, polymers (some examples of which are disclosed below), metal-polymer composites, ceramics, combinations thereof, or the like, or other suitable materials. Some examples of suitable polymers can include polytetrafluoroethylene (PTFE), ethylene tetrafluoroethylene (ETFE), fluorinated ethylene propylene (FEP), polyoxymethylene (POM, available from DuPont, for example), polyoxymethylene (POM ... ), polyether block esters, polyurethanes (e.g., Polyurethane 85A), polypropylene (PP), polyvinyl chloride (PVC), polyether esters (e.g., available from DSM Engineering Plastics) ), ether- or ester-based copolymers (e.g., butylene / poly(alkylene ether) phthalate and / or other polyester elastomers such as those available from DuPont ), polyamides (e.g., available from Bayer Or available from Elf Atochem ), elastic polyamides, block polyamide / ether, polyether block amide (PEBA, for example, available under the trade name ), ethylene vinyl acetate copolymer (EVA), siloxane, polyethylene (PE), Marlex high-density polyethylene, Marlex low-density polyethylene, linear low-density polyethylene (e.g., ), polyester, polybutylene terephthalate (PBT), polyethylene terephthalate (PET), polytrimethylene terephthalate, polyethylene naphthalate (PEN), polyetheretherketone (PEEK), polyimide (PI), polyetherimide (PEI), polyphenylene sulfide (PPS), polyphenylene oxide (PPO), poly(p-phenylene terephthalamide) (e.g., ), polysulfone, nylon, nylon-12 (such as, available from EMS American Grilon) ), perfluoro(propyl vinyl ether) (PFA), ethylene vinyl alcohol, polyolefins, polystyrene, epoxy resins, polyvinylidene chloride (PVdC), poly(styrene-b-isobutylene-b-styrene) (e.g., SIBS and / or SIBS 50A), styrene ethylene butylene styrene (SEBS), thermoplastic elastomers (TPE) (such as available from Hexpol TPE) ), polycarbonate, ionomer, biocompatible polymer, other suitable materials, or mixtures, combinations, copolymers, polymer / metal composites, etc. In some embodiments, the sheath may be blended with a liquid crystal polymer (LCP).

[0117] Some examples of suitable metals and metal alloys include stainless steel (such as 304V, 304L and 316LV stainless steel), mild steel, nickel titanium alloys (such as linear elastic and / or superelastic Nitinol), other nickel alloys (such as nickel chromium molybdenum alloys (e.g., UNS: N06625, such as 625; UNS:N06022, such as UNS:N10276, such as other alloys, etc.)), nickel-copper alloys (e.g., UNS: N04400, such as 400, 400, 400, etc.), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035, such as etc.), nickel-molybdenum alloys (e.g., UNS: N10665, such as ALLOY ), other nickel-chromium alloys, other nickel-molybdenum alloys, other nickel-cobalt alloys, other nickel-iron alloys, other nickel-copper alloys, other nickel-tungsten alloys or tungsten alloys, etc., cobalt-chromium alloys, cobalt-chromium-molybdenum alloys (e.g., UNS: R30003, such as etc.), platinum-rich stainless steel, titanium, combinations thereof, etc., or any other suitable material.

[0118] In at least some embodiments, some or all of the tissue retraction system 10 and / or other components of the tissue retraction system 10 may also be doped with, made from, or otherwise include a radiopaque material. A radiopaque material should be understood as a material that is capable of producing a brighter image on a fluoroscopic screen or another imaging technique during a medical procedure. The brighter image helps a user of the tissue retraction system 10 and / or other components of the tissue retraction system 10 determine their position. Some examples of radiopaque materials may include, but are not limited to, gold, platinum, palladium, tantalum, tungsten alloys, polymer materials with radiopaque fillers, and the like. Additionally, other radiopaque marker bands and / or coils may also be incorporated into the design of the tissue retraction system 10 and / or other components of the tissue retraction system 10 to achieve the same results.

[0119] In some embodiments, a degree of magnetic resonance imaging (MRI) compatibility is imparted to the tissue retraction system 10 and / or other components of the tissue retraction system 10. For example, the tissue retraction system 10 and / or other components of the tissue retraction system 10, or portions thereof, may be made of a material that does not substantially distort the image and does not create significant artifacts (e.g., gaps in the image). For example, certain ferromagnetic materials may be unsuitable because they may produce artifacts on an MRI image. The tissue retraction system 10 and / or other components of the tissue retraction system 10, or portions thereof, may also be made of a material that is imageable by an MRI machine. Some materials that exhibit these properties include, for example, tungsten, cobalt-chromium-molybdenum alloys (e.g., UNS: R30003, such as etc.), nickel-cobalt-chromium-molybdenum alloys (e.g., UNS: R30035, such as etc.), Nitinol, etc., and others.

[0120] It should be understood that the present disclosure is in many respects illustrative only. Changes may be made in detail without exceeding the scope of the present disclosure, particularly with respect to the arrangement of shapes, sizes, and steps. To an appropriate degree, this may include the use of any of the features of an example embodiment being used in other embodiments. Of course, the scope of the present disclosure is defined in the language of the appended claims.

Claims

1. A tissue retraction device, comprising: a first tissue engaging member having a first end configured to engage tissue, and a second end; Connecting components; as well as A tether is coupled to the second end of the first tissue engaging member via the coupling assembly.

2. The tissue retraction device according to claim 1, wherein: The coupling assembly includes a coupling body and a connecting member; The tether is coupled to the coupler body; and The connecting member is coupled to the second end of the first tissue engaging member.

3. The tissue retraction device according to claim 2, wherein: The first tissue engaging member includes first and second jaw members biased by a spring; and the connecting member is coupled to the spring.

4. The tissue retraction device according to claim 2, wherein: The coupling body and the connecting member are rotatable relative to each other.

5. The tissue retraction device according to claim 4, wherein: The coupling body is rotatable about a longitudinal axis of the connecting member.

6. The tissue retraction device according to claim 1, wherein: The first end of the first tissue engaging member is movable between a first configuration and a second configuration; and The second end of the first tissue engaging member extends in a longitudinal direction away from the first end of the first tissue engaging member.

7. The tissue retraction device according to claim 6, wherein: The tether is capable of longitudinally rotating relative to the first tissue engaging member.

8. The tissue retraction device according to claim 1, wherein: The tether is capable of longitudinally rotating relative to the first tissue engaging member.

9. The tissue retraction device according to any one of claims 1 to 8, wherein: The tether is elastic.

10. A tissue retraction device comprising: a first tissue engaging member having a first end movable between a first configuration and a second configuration and a second end extending in a direction away from the first end; as well as A resilient member is coupled to the second end of the first tissue engaging member.

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