Artificial prosthesis and application

Abstract

The artificial prosthesis is prepared and formed by adopting an artificial prosthesis material, the surface of the artificial prosthesis is provided with a fluff layer formed by fluff, the surface of the artificial prosthesis is provided with a suture, the suture is arranged in the fluff layer in a penetrating mode, and the suture is bound and connected to the surface of the artificial prosthesis through the fluff layer. The device can be well applied to arrangement of marking lines on the surfaces of prostheses such as patches, valves and blood vessels, and can be used for connection between a ring formed by sutures and a blood vessel prosthesis when the blood vessel prosthesis of a corrugated pipe structure is prepared, so that the blood vessel prosthesis of the corrugated pipe structure is possibly prepared by adopting a biological material.

Description

Technical Field

[0001] The invention belongs to the field of biomedical technology, and in particular relates to an artificial prosthesis and its application. Background Art

[0002] At present, prostheses such as patches, valves, and blood vessels are widely used in clinical treatment. Prosthetic materials are usually made of polymer fabric materials, biomaterials, etc. During the prosthesis molding process, it is usually necessary to avoid damage to the material itself as much as possible while ensuring the prosthesis's form and function, so that the prosthesis has good performance. Summary of the invention

[0003] The object of the present invention is to provide an artificial prosthesis to reduce the damage to the artificial prosthesis material during the preparation and molding of the artificial prosthesis and to facilitate the preparation of the artificial prosthesis.

[0004] The present invention is achieved through the following technical solutions: The artificial prosthesis is formed by using artificial prosthesis materials. The surface of the artificial prosthesis has a villi layer formed by villi. Sutures are arranged on the surface of the artificial prosthesis. The sutures are inserted into the villi layer and bound and connected to the surface of the artificial prosthesis through the villi layer.

[0005] In some embodiments of the present invention, the villi are connected to the artificial prosthesis material at one end and the free ends of the villi are intertwined with each other or the villi are connected to the artificial prosthesis material at both ends, forming a villi layer that can bind the sutures to the artificial prosthesis when the sutures are inserted into the villi layer.

[0006] In some embodiments of the present invention, the artificial prosthesis material is a biological material having a villi layer on the surface.

[0007] In some embodiments of the present invention, the biological material is bovine pericardium material.

[0008] In some embodiments of the present invention, the artificial prosthesis material is a non-biological material, and the villi layer is formed on the surface of the non-biological material.

[0009] On the other hand, the present invention also provides a use of the artificial prosthesis as a patch, a valve, or a vascular prosthesis.

[0010] In some embodiments of the present invention, the suture forms a marking line on the surface of the artificial prosthesis.

[0011] In some embodiments of the present invention, the artificial prosthesis is tubular, and the sutures are wound around the artificial prosthesis to form multiple closed loops on the artificial prosthesis. The loops constrain the artificial prosthesis at corresponding positions, so that the artificial prosthesis has a corrugated tubular structure with troughs at the positions of the loops and peaks between the loops.

[0012] Compared with the prior art, the present invention has the following advantages and beneficial effects: A villi layer is formed on the surface of the prosthetic material by utilizing the villi inherent in the surface of the prosthetic material or the villi prepared on the surface of the prosthetic material. The villi layer is used as the basis for connecting the structures such as sutures provided in the preparation of the artificial prosthesis with the artificial prosthesis. When it is necessary to connect sutures such as marking lines to the artificial prosthesis, the sutures can be stably connected to the artificial prosthesis without penetrating the prosthetic material, thereby avoiding the problem of leakage at the suture penetration position on the artificial prosthesis caused by the need to penetrate the artificial prosthesis material during connection, thereby ensuring the performance of the prepared artificial prosthesis material and facilitating the preparation of the artificial prosthesis.

[0013] The present invention can be well applied to setting marking lines on the surface of prostheses such as patches, valves, and blood vessels, and can be used to connect the ring formed by sutures and the vascular prosthesis when preparing a vascular prosthesis with a bellows structure, making it possible to prepare a vascular prosthesis with a bellows structure using biomaterials. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings in the embodiments will be briefly introduced below. It should be understood that the following drawings only show certain embodiments of the present invention and therefore should not be regarded as limiting the scope. For ordinary technicians in this field, other related drawings can be obtained based on these drawings without creative work.

[0015] Figure 1 It is a schematic diagram of the connection structure between the sutures and the villi layer provided on the surface of the sheet-like artificial prosthesis in an embodiment of the present invention.

[0016] Figure 2 It is a schematic diagram of the connection structure between the sutures and the villi layer provided on the surface of the tubular artificial prosthesis in an embodiment of the present invention.

[0017] Figure 3 It is a structural schematic diagram of the application of the method of connecting sutures by using the villus layer in the preparation of a corrugated tubular vascular prosthesis in an embodiment of the present invention.

[0018] in: 10. Artificial prosthesis, 11. Villus layer; 21. Marking line, 22. Ring. DETAILED DESCRIPTION

[0019] In order to make the purpose, technical solutions and advantages of the embodiments of the present invention clearer, the technical solutions in the embodiments of the present invention will be clearly and completely described below in conjunction with the drawings in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments.

[0020] In the application of preparing artificial prostheses using artificial prosthesis materials, taking the setting of marking lines on the prepared artificial prostheses as an example, in order to be able to stably connect the marking lines to the surface of the artificial prosthesis, it is usually necessary to sew the sutures used to form the marking lines to the artificial prosthesis. The artificial prosthesis obtained by this preparation method has the risk of leakage at the pinholes formed by sewing the sutures, which affects the performance of the artificial prosthesis.

[0021] In some other application scenarios of artificial prosthesis preparation, for example, when using biological materials to prepare a corrugated tube-shaped vascular prosthesis, refer to Figure 3 One molding method used is to wrap sutures around a pre-molded tube body, and form multiple closed rings on the tube body through the sutures. These rings restrain the tube body at corresponding positions to form troughs on the tube body, and at the same time, peaks are formed on the tube body at the positions between the rings, thereby forming a corrugated tube-shaped vascular prosthesis.

[0022] An important prerequisite for forming the corrugated tubular vascular prosthesis by the above-mentioned forming method is that the ring formed by the suture can be stably connected to the tube body, so there is also a need for how to fix the suture to the artificial prosthesis.

[0023] Based on the above-mentioned practical needs and problems existing in the preparation of artificial prostheses, when using biological materials such as bovine pericardium to prepare artificial prostheses, it is found that there is a villus layer formed by villi on the surface of one side of the bovine pericardium material. The structural characteristics of these villi are that some villi are connected to the bovine pericardium at one end and intertwined with each other at the other end, and some villi are connected to the bovine pericardium material at both ends. At this time, there will be a large number of closed pores inside the villus layer on the surface of the bovine pericardium material. By utilizing the closed pores in the villus layer, when the suture is passed into the villus layer, the suture can be stably bound and connected to the surface of the artificial prosthesis.

[0024] Based on the above structural characteristics of biomaterials, the inventors applied them to the preparation of artificial prostheses, which effectively solved the problems of poor connection and leakage at the connection position when sutures are set on the surface of artificial prostheses.

[0025] In some embodiments of the present invention, referring to Figure 1 The artificial prosthesis 10 is formed by using artificial prosthesis materials. The surface of the artificial prosthesis has a villi layer 11 formed by villi. Sutures are arranged on the surface of the artificial prosthesis 10. The sutures are passed through the villi layer 11 and are bound and connected to the surface of the artificial prosthesis through the villi layer.

[0026] In some embodiments, the villi are connected to the artificial prosthesis material at one end and the free ends of the villi are intertwined with each other, or the villi are connected to the artificial prosthesis material at both ends, forming a villi layer that can bind the sutures connected to the artificial prosthesis when the sutures are inserted into the villi layer, so that the formed villi layer has a large number of closed pores inside.

[0027] In some embodiments, the artificial prosthesis material can directly adopt biological materials with a villus layer on the surface, such as human or animal pericardium and other similar thin slices of tissue, such as bovine pericardium material. When such biological materials are used to prepare artificial prostheses, the villus layer on the surface can be used to achieve stable connection of sutures on the surface of the artificial prosthesis.

[0028] Artificial prosthesis materials can also be made of non-biological materials, such as membranes made of polymer materials. The surface of this membrane is usually a smooth surface, and it is difficult to fix sutures on its surface without damaging the membrane material. Based on the technical ideas in the present invention, a villi layer with the above-mentioned structural characteristics can be formed on the surface of the non-biological material, and then the villi layer can be used to connect the sutures, which effectively solves the problems existing in the preparation of artificial prostheses using non-biological materials.

[0029] The artificial prosthesis here can be a patch, a valve, a vascular prosthesis, etc., and is certainly not limited to the prosthetic products listed above.

[0030] On the other hand, some embodiments of the present invention also involve the use of the above-mentioned artificial prosthesis as a patch, a valve, or a vascular prosthesis.

[0031] In the above application, the sutures arranged on the surface of the artificial prosthesis form a marking line 21 on the surface of the artificial prosthesis. Figure 1 Taking setting a marking line on the patch surface as an example, at this time, it is only necessary to pass the suture into the villi layer to form the required marking line 21 on the patch surface, and the marking line can be stably connected to the surface of the patch.

[0032] Taking the application in vascular prosthesis as an example, when using biomaterials to prepare vascular prosthesis with corrugated tube structure, refer to Figure 2 and Figure 3 One of the molding methods adopted is to curl the sheet-like biomaterial and sew it into a tube, then wrap sutures around the tube to form a plurality of closed rings 22 arranged at intervals on the tube, and use the rings to restrain the artificial prosthesis at corresponding positions. At this time, the artificial prosthesis prepared in the inflated state will form troughs at the positions where the rings are located, and the parts between the rings will form peaks, thereby obtaining a vascular prosthesis with a corrugated tubular structure.

[0033] Of course, refer to Figure 3A marking line 21 may also be provided on the surface of the vascular prosthesis along its axial direction. The marking line 21 penetrates the villous layer on the surface of the vascular prosthesis and is connected to the vascular prosthesis.

[0034] Taking the tube body formed by bovine pericardium material as an example, the bovine pericardium material is usually smooth on one side and has villi on the other side. During the forming process, the smooth surface of the bovine pericardium forms the inner wall of the tube body, and the outer wall of the tube body is attached with a villi layer 11 formed by villi. The villi layer 11 is similar to the adhesive surface of Velcro, and a hole is formed inside for the suture to pass through. In this way, when the suture is inserted into the villi layer, the loop formed by the suture can be stably connected to the outer wall of the tube body by utilizing the structural characteristics of the villi layer.

[0035] In the preparation of the above-mentioned vascular prosthesis, the ring is connected to the tube body through the villous layer on the outer wall of the tube body, which not only facilitates the connection of the constraining ring on the outer wall of the tube body, but also the connection of the constraining ring on the tube body will not cause any damage to the bovine pericardial material. It has great practical application value and significance in the preparation and application of artificial prostheses.

[0036] In the description of the present invention, it should be noted that the terms "center", "up", "down", "left", "right", "vertical", "horizontal", "inside", "outside", etc. used to indicate the orientation or position relationship are based on the orientation or position relationship shown in the accompanying drawings, or are the orientation or position relationship commonly placed when the product of the invention is used. They are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0037] In addition, if the terms "horizontal" or "vertical" appear in the description of the present invention, it does not mean that the components are required to be absolutely horizontal or suspended, but can be slightly tilted. For example, "horizontal" only means that its direction is more horizontal than "vertical", and does not mean that the structure must be completely horizontal, but can be slightly tilted.

[0038] In the description of the present invention, it is also necessary to explain that, unless otherwise clearly specified and limited, the terms "set", "install", "connect", and "connect" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in the present invention can be understood in combination with specific circumstances.

[0039] The above description is only a preferred embodiment of the present invention and does not limit the present invention in any form. Any simple modification or equivalent change made to the above embodiment based on the technical essence of the present invention shall fall within the protection scope of the present invention.

Claims

1. An artificial prosthesis, characterized in that: The artificial prosthesis is prepared by artificial prosthesis material. The surface of the artificial prosthesis has a villi layer formed by villi. Sutures are arranged on the surface of the artificial prosthesis. The sutures are inserted into the villi layer and bound and connected to the surface of the artificial prosthesis through the villi layer.

2. The artificial prosthesis according to claim 1, characterized in that: The villi are connected to the artificial prosthesis material at one end and the free ends of the villi are intertwined with each other or the villi are connected to the artificial prosthesis material at both ends, forming a villi layer that can bind and connect the suture to the artificial prosthesis when the suture is inserted into the villi layer.

3. The artificial prosthesis according to claim 1 or 2, characterized in that: The artificial prosthesis material is a biological material with a villi layer on the surface.

4. The artificial prosthesis according to claim 3, characterized in that: The biological material is bovine pericardium material.

5. The artificial prosthesis according to claim 1 or 2, characterized in that: The artificial prosthesis material is a non-biological material, and the fluff layer is formed on the surface of the non-biological material.

6. Use of the artificial prosthesis according to any one of claims 1 to 5 as a patch, valve or vascular prosthesis.

7. The use according to claim 6, characterized in that: The sutures form marking lines on the surface of the artificial prosthesis.

8. The use according to claim 6, characterized in that: The artificial prosthesis is tubular, and the sutures are wound around the artificial prosthesis to form multiple closed loops on the artificial prosthesis. The loops constrain the artificial prosthesis at corresponding positions, so that the artificial prosthesis has a corrugated tubular structure with troughs at the positions of the loops and peaks between the loops.

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