Auxiliary fixing device for PET-CT (positron emission tomography-computed tomography) examination of experimental animals

Abstract

The invention relates to the technical field of animal experiments, and particularly discloses an experimental animal PET-CT examination auxiliary fixing device which comprises a fixing base, the upper surface of the fixing base is fixedly connected with a first supporting column, the upper surface of the first supporting column is fixedly connected with a first limiting plate, and the side surface of the first limiting plate is fixedly connected with two supporting limiting blocks. The experimental animal PET-CT examination auxiliary fixing device is provided with a supporting limiting block and a positioning sliding rail, when the experimental animal PET-CT examination auxiliary fixing device works, by sliding a second supporting column, a transmission rolling wheel at the lower end of the second supporting column is used for supporting, friction force is dropped through rotation of the transmission rolling wheel, and therefore practicability is improved; and a second supporting column is conveniently guided, so that the movement stability of the second supporting column is improved, the distance between a first limiting plate and a second limiting plate is conveniently changed, and the convenience of fixing different rabbits is improved.

Description

Technical Field

[0001] The invention relates to the technical field of animal experiments, in particular to an auxiliary fixing device for PET-CT examination of experimental animals. Background Art

[0002] PET principle: When a radioactive nuclide-containing contrast agent is injected into the human body, the contrast agent will have a specific distribution. The positrons emitted by the radioactive nuclide collide with the negative electrons in the human tissue within a very short distance and "annihilate", releasing a pair of gamma rays with the same energy but in opposite directions. The PET equipment is used to detect and record these gamma rays, and then through computer processing, the distribution and density of the radioactive drug in the human body can be presented, thereby reflecting the state of the disease. CT principle: The human body is scanned by X-rays. According to the different degrees of X-ray absorption by different tissues, images of different grayscales are formed after calculation and processing, depicting the tissue structure of the human body. Fusion principle: PET provides functional and metabolic images of lesions, and CT provides precise anatomical positioning of lesions. The two images are fused together through software to achieve the combination of functional metabolism and anatomical morphology imaging.

[0003] PET-CT is widely used in animal experiments. It can be used to observe the growth, proliferation and metastasis of tumor cells in animals in real time and dynamically. In the process of drug development, PET-CT can be used to evaluate the efficacy of drugs. By observing the changes in the uptake of imaging agents by tumor tissues, it can be determined whether the drugs have inhibited the metabolism of tumor cells, thereby providing an important basis for drug screening and optimization. For neurodegenerative diseases such as Parkinson's disease and Alzheimer's disease, PET-CT can detect metabolic changes in specific areas of the brain. In the study of repair after nerve damage, PET-CT can monitor the metabolism and functional recovery of neural tissue. In animal myocardial ischemia models, PET-CT can accurately display myocardial blood perfusion and the metabolic state of myocardial cells. PET-CT can be used to observe inflammatory reactions and lipid deposition in the arterial wall.

[0004] During PET-CT examinations, in order to ensure the accuracy of imaging, experimental animals must remain completely still. Since it is difficult for rabbits to remain still for a long time in their natural state, a special fixing structure needs to be carefully designed and made. In the existing PET-CT scanning process, due to certain differences in body shape between different rabbits, the existing fixing devices are less effective in adapting to rabbits of different sizes, making it difficult to accurately fix the rabbits, resulting in the rabbits moving due to discomfort after being restrained, which in turn affects the scanning effect. Summary of the invention

[0005] The purpose of the present invention is to provide an auxiliary fixation device for PET-CT examination of experimental animals, so as to solve the problem that the existing fixation device proposed in the above background technology has poor effect in adapting to rabbits of different sizes, is difficult to accurately fix the rabbit, causes the rabbit to move due to discomfort after being restrained, and thus affects the scanning effect.

[0006] To achieve the above-mentioned purpose, the present invention provides the following technical solutions: an experimental animal PET-CT examination auxiliary fixing device, comprising a fixed base, a first support column is fixedly connected to the upper surface of the fixed base, a first limit plate is fixedly connected to the upper surface of the first support column, two support limit blocks are fixedly connected to the side surface of the first limit plate, a second support column is arranged on the upper surface of the fixed base, a positioning slide rail is installed on the side of the second support column, a transmission roller is installed on the lower surface of the second support column, a second limit plate is fixedly connected to the upper surface of the second support column, a lower positioning plate is fixedly connected to the lower surface of the second limit plate, and a transmission roller is installed on the surface of the lower positioning plate. Screw, the upper end of the transmission screw is provided with an extrusion slider, the surface of the second limit plate is connected with two translation sliders, one end of the translation slider is fixedly connected with a linkage block, the outer surface of the support limit block is provided with a locking groove, the surfaces of the first limit plate and the second limit plate are provided with limb openings, the outer surfaces of the first support column and the second support column are fixedly connected with elastic connecting ropes, and an elastic locking belt is connected between the two elastic connecting ropes, a head limiting strap is installed on the upper surface of the first limit plate, and a linkage clamping mechanism is provided on the inner wall of the limb opening, which drives the pressing splint and the linkage piston column to move by rotating the adjusting screw to inflate the fitting airbag.

[0007] Preferably, the support limit block passes through the surface of the second limit plate, and the support limit block and the second limit plate are slidably connected, and the second support column and the positioning slide rail are slidably connected.

[0008] By adopting the above technical scheme, the support limit block passes through the surface of the second limit plate. The second limit plate is an important component that plays a limiting and positioning role in the entire structure. The support limit block can slide smoothly in the through hole of the second limit plate, so that the support limit block slides to a specific position in the second limit plate, thereby providing stable support or accurate limitation for other components. The end of the second support column is designed to be compatible with the positioning slide rail so that it can achieve smooth sliding on the positioning slide rail. During operation, the second support column slides along the direction of the positioning slide rail, and the positioning slide rail guides and positions the second support column.

[0009] Preferably, the lower positioning plate is L-shaped, and the lower positioning plate is threadedly connected to the transmission screw, the transmission screw is rotationally connected to the extrusion slider, and the extrusion slider is slidingly connected to the second limit plate.

[0010] By adopting the above technical solution, when the transmission screw rotates, the rotational motion will be converted into linear motion of the lower positioning plate by virtue of the interaction between the threads. This motion conversion method has high precision and controllability. By controlling the rotation direction and speed of the transmission screw, the position of the lower positioning plate can be accurately adjusted, thereby achieving precise adjustment of the positions of related components in the entire mechanical structure. When the transmission screw rotates to drive the extrusion slider to move, the extrusion slider will slide along the sliding surface of the second limit plate, thereby achieving actions such as extrusion or pushing of other components, playing an important role in the entire mechanical system.

[0011] Preferably, both ends of the extrusion slider are designed to be arc-shaped, the translation slider is slidably connected to the second limit plate, the side surface of the linkage block is designed to be inclined, and a spring is connected between the linkage block and the second limit plate.

[0012] By adopting the above technical scheme, when the extrusion slider interacts with other components, the two ends of the arc can avoid stress concentration on sharp corners, thereby greatly reducing the risk of damage to the slider and extending its service life. The arc design also makes the extrusion slider smoother when in contact with other components. The bottom or side of the translation slider fits perfectly with the sliding surface of the second limit plate, and the gap between the two is precisely calculated and debugged, which not only ensures that the translation slider can slide freely on the second limit plate, but also other components can slide or move along the inclined side surface of the linkage block during mechanical movement, thereby realizing the linkage effect between different components. The inclined side surface can also buffer the impact force between components to a certain extent and reduce damage caused by collision. A spring is connected between the linkage block and the second limit plate. This spring plays an important role. It provides elastic support and reset function for the linkage block.

[0013] Preferably, the limb openings are of cylindrical design, the elastic locking band is of telescopic design, and a Velcro is provided on the outer surface of one end of the elastic locking band, and the head limiting strap is of elastic design.

[0014] With the above technical solution, the limb opening needs to withstand a certain amount of external force and pressure. The cylindrical structure can evenly disperse these forces, making the opening part less likely to deform or be damaged. Velcro is provided on the outer surface of one end of the elastic locking belt. Velcro is a simple and practical connection method, which greatly facilitates the use of the elastic locking belt. The head limiting strap adopts an elastic design, which is to better adapt to the head size and shape of different rabbits. The head size and contour of each rabbit are different. The elastic head limiting strap can automatically adjust its own length and tension to adapt to various head features.

[0015] Preferably, the linkage clamping mechanism includes an adjusting screw, which is installed through the side surfaces of the first limit plate and the second limit plate. A pressing splint is installed on the outer surface of one end of the adjusting screw. A linkage piston column is fixedly connected to the side of the pressing splint, and a fitting airbag is fixedly connected to the inner wall of the limb opening.

[0016] With the above technical solution, in the design system of the entire mechanical device, the linkage clamping mechanism is a vital component, which undertakes the key tasks of precise clamping and stable fixation. One of the core components of the linkage clamping mechanism is the adjusting screw, which is installed through the side surfaces of the first limit plate and the second limit plate in an ingenious and rigorous way. The first limit plate and the second limit plate play an important positioning and supporting role in the entire mechanical structure. Their materials are usually carefully selected and have sufficient strength and rigidity to ensure that they can withstand the various forces generated by the adjusting screw during operation. The installation process of the adjusting screw requires a high degree of precision, and the aperture size and position accuracy of the hole that passes through the first limit plate and the second limit plate have strict requirements. During installation, it is necessary to ensure that the adjusting screw can rotate smoothly in the hole of the limit plate, while avoiding excessive gaps that cause shaking.

[0017] Preferably, the adjusting screw is rotationally connected with the first limit plate and the second limit plate respectively, and the adjusting screw is threadedly connected with the pressing splint, one end of the pressing splint passes through the inner wall of the limb opening, and one end of the pressing splint is arc-shaped.

[0018] With the above technical solution, a pressing splint is installed on the outer surface of one end of the adjusting screw. The pressing splint is the direct actuator of the linkage clamping mechanism to realize the clamping function, and its design and manufacture are also very sophisticated. The surface of the pressing splint is usually specially treated to increase the friction between it and the clamped object to ensure that there is no sliding during the clamping process. The material selection must ensure that it has sufficient hardness to apply pressure and a certain toughness to prevent breakage when excessive force is applied. When the adjusting screw rotates, it will drive the pressing splint to move along the axial direction of the screw, thereby realizing the clamping or loosening operation of the object. This method of controlling the movement of the splint through screw transmission has high precision and controllability, and can accurately adjust the clamping force according to actual needs.

[0019] Preferably, the pressing clamp is slidably connected to the first limit plate and the second limit plate respectively, and the linkage piston column is slidably connected to the first limit plate and the second limit plate respectively.

[0020] With the above technical solution, the side of the pressing splint is fixedly connected with a linkage piston column. The linkage piston column plays an important role in linking the movement of the pressing splint with other components. When the pressing splint moves driven by the adjusting screw, the linkage piston column will be displaced accordingly, thereby driving other components connected thereto to move. The linkage piston column can convert the movement of the pressing splint into the movement of other actuators through the transmission of the ball control, thereby realizing the coordinated work between multiple components.

[0021] Preferably, a communicating air groove is provided between one end of the linkage piston column and the cavity of the fitting airbag, the fitting airbag is arc-shaped, and the fitting airbag and the pressing splint are arranged opposite to each other.

[0022] With the above technical solution, the inner wall of the limb opening is fixedly connected with a fitting airbag. The limb opening is designed to facilitate the placement of the rabbit's limbs into the device. The presence of the fitting airbag greatly improves the rabbit's comfort and the fit of the device. The fitting airbag is generally made of soft and elastic material. When the user places the limbs into the limb opening, the fitting airbag will adaptively deform according to the shape and pressure of the limbs and fit tightly to the surface of the limbs. This fit can not only reduce the gap between the device and the limbs, improve the stability of the device, but also disperse the pressure. The fitting airbag can also play a certain buffering role, reducing the damage to the limbs when the device is subjected to external impact.

[0023] Compared with the prior art, the invention has the following beneficial effects: the auxiliary fixation device for PET-CT examination of experimental animals:

[0024] 1. A support limit block and a positioning slide rail are provided, so that when the device is working, the second support column is slid to support the transmission roller at the lower end of the second support column, and the friction force is reduced by the rotation of the transmission roller, thereby increasing the practicality, and the second support column is conveniently guided by the limitation of the positioning slide rail, thereby increasing the stability of the movement of the second support column, thereby facilitating the change of the distance between the first limit plate and the second limit plate, thereby improving the convenience of fixing different rabbits;

[0025] 2. An extrusion slider and a translation slider are provided, so that when the device is working, the stability of the mutual movement of the first limit plate and the second limit plate is increased by the support limit block. By rotating the transmission screw, it is convenient for the transmission screw to drive the extrusion slider to move up and down, thereby increasing the stability of the movement of the extrusion slider. The extrusion slider pushes the linkage block through the arc design at both ends, so that the linkage block drives the translation slider to slide. The locking groove on the surface of the support limit block is plugged and fixed by the translation slider, thereby increasing the stability of the first limit plate and the second limit plate;

[0026] 3. An adjusting screw and a pressing splint are provided so that when the device is working, after the rabbit's limbs are passed through the limb openings, the adjusting screw is rotated to drive the pressing splint to slide horizontally through the thread, so that the pressing splint moves to clamp and fix the limbs. At the same time, the movement of the pressing splint drives the linkage piston column to slide, and the linkage piston column pushes the air on one side into the fitting airbag, which is convenient for the fitting airbag to expand and deform. The fitting airbag supports and wraps the limbs, thereby increasing the stability of the limb limitation. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] Figure 1 It is a schematic diagram of a three-dimensional structure of a fixed base and a first support column connected to each other in the present invention;

[0028] Figure 2 This is a schematic diagram of a three-dimensional structure of a first support column and a first limiting plate connected to each other in the present invention;

[0029] Figure 3 It is a schematic diagram of the three-dimensional structure of the connection between the first limiting plate and the supporting limiting block of the present invention;

[0030] Figure 4 This is a schematic diagram of the three-dimensional structure of the second support column and the transmission roller connected to the present invention;

[0031] Figure 5 For the present invention Figure 4 The enlarged structural diagram at A in the middle;

[0032] Figure 6 It is a schematic diagram of the three-dimensional structure of the connection between the transmission screw and the extrusion slider of the present invention;

[0033] Figure 7 This is a schematic diagram of the three-dimensional structure of the connection between the support limit block and the locking groove of the present invention;

[0034] Figure 8 This is a schematic diagram of the three-dimensional structure of the connection between the adjusting screw and the pressing clamping plate of the present invention;

[0035] Fig. 9 It is a schematic diagram of the three-dimensional structure of the connection between the pressing clamp and the linkage piston column of the present invention.

[0036] In the figure: 1. fixed base; 2. first support column; 3. first limit plate; 4. support limit block; 5. second support column; 6. positioning slide rail; 7. transmission roller; 8. second limit plate; 9. lower positioning plate; 10. transmission screw; 11. extrusion slider; 12. translation slider; 13. linkage block; 14. locking groove; 15. limb opening; 16. elastic locking belt; 17. elastic connecting rope; 18. head limit strap; 19. adjustment screw; 20. pressing splint; 21. linkage piston column; 22. fitting airbag. DETAILED DESCRIPTION

[0037] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0038] See also Figure 1-9 The present invention provides a technical solution: an experimental animal PET-CT examination auxiliary fixing device, comprising a fixed base 1, a first support column 2, a first limiting plate 3, a supporting limiting block 4, a second support column 5, a positioning slide rail 6, a transmission roller 7, a second limiting plate 8, a lower positioning plate 9, a transmission screw 10, an extrusion slider 11, a translation slider 12, a linkage block 13, a locking groove 14, a limb opening 15, an elastic locking belt 16, an elastic connecting rope 17, a head limiting strap 18, an adjusting screw 19, a pressing splint 20, a linkage piston column 21 and a fitting airbag 22, the fixed base 1, the upper surface of which is fixedly connected to the first support column 2, the upper surface of the first support column 2 is fixedly connected to the first limiting plate 3, the side surface of the first limiting plate 3 is fixedly connected to two supporting limiting blocks 4, and the supporting limiting blocks 4 penetrate the surface of the second limiting plate 8. The support limit block 4 is slidably connected with the second limit plate 8, the second support column 5 is slidably connected with the positioning slide rail 6, the lower positioning plate 9 is L-shaped, and the lower positioning plate 9 is threadedly connected with the transmission screw 10, the transmission screw 10 is rotatably connected with the extrusion slider 11, and the extrusion slider 11 is slidably connected with the second limit plate 8. When using this device, first adjust the distance between the first limit plate 3 and the second limit plate 8 according to the size of the rabbit, and drive the extrusion slider 11 to descend by rotating the transmission screw 10 to release the translation slider 12 and the linkage block 13, so that the translation slider 12 is not plugged into the support limit block 4, and the second support column 5 is supported by the transmission roller 7 through sliding, thereby reducing wear and tear, and guiding the positioning slide rail 6 to increase the stability of the second support column 5.

[0039] A second support column 5 is arranged on the upper surface of the fixed base 1, a positioning slide rail 6 is installed on the side of the second support column 5, a transmission roller 7 is installed on the lower surface of the second support column 5, a second limit plate 8 is fixedly connected to the upper surface of the second support column 5, a lower positioning plate 9 is fixedly connected to the lower surface of the second limit plate 8, a transmission screw 10 is installed through the surface of the lower positioning plate 9, both ends of the extrusion slider 11 are arc-shaped, the translation slider 12 is slidably connected with the second limit plate 8, the side surface of the linkage block 13 is inclined, and a spring is connected between the linkage block 13 and the second limit plate 8, the limb opening 15 is cylindrical, the elastic locking belt 16 is telescopic, and the elastic A Velcro is provided on the outer surface of one end of the locking belt 16, and the head limiting strap 18 is designed to be elastic. After the adjustment is completed, the transmission screw 10 at the lower end of the lower positioning plate 9 is rotated to drive the extrusion slider 11 to rise and fall, so that the extrusion slider 11 squeezes the linkage block 13 to drive the translation slider 12 to slide and get into the locking groove 14, thereby fixing the first limiting plate 3, the supporting limiting block 4 and the second limiting plate 8, and then inserting the limbs of the experimental rabbit into the limb openings 15, and tightening them through the Velcro on the surface of the elastic locking belt 16, so as to lock the limbs of the rabbit, and the head of the rabbit is bound and limited by the head limiting strap 18, which effectively prevents the rabbit from twitching during the experimental inspection process.

[0040] An extrusion slider 11 is provided at the upper end of the transmission screw 10, two translation sliders 12 are connected to the surface of the second limit plate 8, one end of the translation slider 12 is fixedly connected to a linkage block 13, a locking groove 14 is provided on the outer surface of the support limit block 4, and the surfaces of the first limit plate 3 and the second limit plate 8 are both provided with limb openings 15. The linkage clamping mechanism includes an adjusting screw 19, which is installed on the side surfaces of the first limit plate 3 and the second limit plate 8, and a pressing splint 20 is installed on the outer surface of one end of the adjusting screw 19. A linkage piston column 21 is fixedly connected to the side of the pressing splint 20. The limb openings 15 are provided with a locking groove 14, and the surfaces of the first limit plate 3 and the second limit plate 8 are provided with a locking groove 14. The locking groove 14 is provided with a locking groove 14, and the surfaces of the first limit plate 3 and the second limit plate 8 are both provided with a locking groove 14. The locking groove 14 is provided with a locking groove 14, and the locking groove 14 is ... A fitting airbag 22 is fixedly connected to the inner wall, and the adjusting screw 19 is rotatably connected to the first limit plate 3 and the second limit plate 8 respectively. The adjusting screw 19 is threadedly connected to the pressing splint 20, and one end of the pressing splint 20 passes through the inner wall of the limb opening 15, and one end of the pressing splint 20 is arc-shaped. After the rabbit's limbs pass through the limb opening 15, the adjusting screw 19 is rotated so that the adjusting screw 19 drives the pressing splint 20 to slide relative to the inner wall of the limb opening 15 through the thread, so that the arc surface of one end of the pressing splint 20 presses the side of the rabbit's limbs, further improving the stability of the rabbit's limbs.

[0041] The outer surfaces of the first support column 2 and the second support column 5 are fixedly connected with elastic connecting ropes 17, and an elastic locking belt 16 is connected between the two elastic connecting ropes 17. A head limiting strap 18 is installed on the upper surface of the first limit plate 3. A linkage clamping mechanism is arranged on the inner wall of the limb opening 15, which drives the pressing splint 20 and the linkage piston column 21 to move by rotating the adjusting screw 19 to inflate the fitting airbag 22. The pressing splint 20 is respectively slidably connected with the first limit plate 3 and the second limit plate 8, and the linkage piston column 21 is respectively connected with the first limit plate 3 and the second limit plate 8. The limiting plate 8 forms a sliding connection, and a connecting air groove is opened between one end of the linkage piston column 21 and the cavity of the fitting airbag 22. The fitting airbag 22 is of arc-shaped design, and the fitting airbag 22 is arranged opposite to the pressing splint 20. When the pressing splint 20 slides, the pressing splint 20 drives the linkage piston column 21 on the side to move, so that the linkage piston column 21 pushes the air on one side into the cavity of the fitting airbag 22, which is convenient for the fitting airbag 22 to restart and expand and deform. The rabbit's limbs are wrapped and supported by the fitting airbag 22, which increases comfort while preventing slip and stability.

[0042] Working principle: When using the experimental animal PET-CT examination auxiliary fixation device, according to the size of the experimental rabbit, the transmission screw 10 is rotated to drive the squeezing slider 11 to descend, the translation slider 12 and the linkage block 13 are loosened, and the distance between the first limit plate 3 and the second limit plate 8 is adjusted by sliding the second support column 5. After the adjustment is completed, the transmission screw 10 is rotated to drive the squeezing slider 11 to rise and squeeze the linkage block 13, and drive the translation slider 12 to slide and snap into the locking groove 14, and the limbs of the experimental rabbit are inserted into the limb openings 15. The rabbit is bound and limited by the elastic locking belt 16 and the head limiting strap 18. After the rabbit's limbs pass through the limb openings 15, the adjusting screw 19 is rotated to drive the pressing splint 20 to press the sides of the rabbit's limbs through the thread. When the pressing splint 20 slides, the linkage piston column 21 moves, and the air on one side is pushed into the cavity of the fitting airbag 22, thereby inflating and expanding and deforming, wrapping and supporting the rabbit's limbs, thereby increasing the overall practicality.

[0043] Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that various changes, modifications, substitutions and variations may be made to the embodiments without departing from the principles and spirit of the present invention, and that the scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An auxiliary fixing device for PET-CT examination of experimental animals, comprising a fixing base (1), the upper surface of which is fixedly connected to a first supporting column (2), the upper surface of which is fixedly connected to a first limiting plate (3), characterized in that: The side surface of the first limit plate (3) is fixedly connected with two support limit blocks (4); the upper surface of the fixed base (1) is provided with a second support column (5); the side of the second support column (5) is installed with a positioning slide rail (6); the lower surface of the second support column (5) is installed with a transmission roller (7); the upper surface of the second support column (5) is fixedly connected with a second limit plate (8); the lower surface of the second limit plate (8) is fixedly connected with a lower positioning plate (9); a transmission screw (10) is installed through the surface of the lower positioning plate (9); the upper end of the transmission screw (10) is provided with an extrusion slider (11); the surface of the second limit plate (8) is connected with two translation sliders (12); the translation sliders (12 ) is fixedly connected to one end of a linkage block (13), a locking groove (14) is provided on the outer surface of the support limit block (4), limb openings (15) are provided on the surfaces of the first limit plate (3) and the second limit plate (8), elastic connecting ropes (17) are fixedly connected to the outer surfaces of the first support column (2) and the second support column (5), and an elastic locking belt (16) is connected between the two elastic connecting ropes (17), a head limiting strap (18) is installed on the upper surface of the first limit plate (3), and a linkage clamping mechanism is provided on the inner wall of the limb opening (15), which drives the pressing clamp (20) and the linkage piston column (21) to move by rotating the adjusting screw (19) to inflate the fitting airbag (22).

2. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 1, characterized in that: The support limit block (4) passes through the surface of the second limit plate (8), and the support limit block (4) and the second limit plate (8) are slidably connected, and the second support column (5) and the positioning slide rail (6) are slidably connected.

3. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 1, characterized in that: The lower positioning plate (9) is of L-shaped design, and the lower positioning plate (9) is threadedly connected to the transmission screw (10), the transmission screw (10) is rotationally connected to the extrusion slider (11), and the extrusion slider (11) is slidingly connected to the second limit plate (8).

4. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 1, characterized in that: The two ends of the extrusion slider (11) are designed to be arc-shaped, the translation slider (12) is slidably connected to the second limit plate (8), the side surface of the linkage block (13) is designed to be inclined, and a spring is connected between the linkage block (13) and the second limit plate (8).

5. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 1, characterized in that: The limb openings (15) are of cylindrical design, the elastic locking belt (16) is of telescopic design, and a Velcro is provided on the outer surface of one end of the elastic locking belt (16), and the head limiting strap (18) is of elastic design.

6. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 1, characterized in that: The linkage clamping mechanism comprises an adjusting screw (19), which is installed through the side surfaces of the first limit plate (3) and the second limit plate (8); a pressing clamp (20) is installed on the outer surface of one end of the adjusting screw (19); a linkage piston column (21) is fixedly connected to the side of the pressing clamp (20); and a fitting airbag (22) is fixedly connected to the inner wall of the limb opening (15).

7. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 6, characterized in that: The adjusting screw (19) is rotatably connected to the first limit plate (3) and the second limit plate (8) respectively, and the adjusting screw (19) is threadedly connected to the pressing clamp (20), one end of the pressing clamp (20) passes through the inner wall of the limb opening (15), and one end of the pressing clamp (20) is designed to be arc-shaped.

8. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 6, characterized in that: The pressing clamp (20) is slidably connected to the first limit plate (3) and the second limit plate (8), respectively, and the linkage piston column (21) is slidably connected to the first limit plate (3) and the second limit plate (8), respectively.

9. The auxiliary fixation device for PET-CT examination of experimental animals according to claim 6, characterized in that: A communicating air groove is provided between one end of the linkage piston column (21) and the cavity of the fitting airbag (22); the fitting airbag (22) is arc-shaped, and the fitting airbag (22) and the pressing clamp (20) are arranged opposite to each other.

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