Valve repair system

Abstract

The invention discloses a valve repair system which comprises a valve repair device and a delivery device. The valve repair device comprises at least one pair of clamping parts and at least one pair of elastic clamping parts, in a natural state, the pair of clamping parts are far away from each other and are respectively attached to the opposite clamping parts; the delivery device at least comprises a pushing assembly, the pushing assembly comprises a pushing catheter, the valve repair device is detachably connected with the far end of the pushing catheter, the pushing catheter is provided with a plurality of channels penetrating through the near end and the far end of the pushing catheter, and the channels at least comprise two opposite channels opposite to the two clamping parts in the axial direction; the valve repairing system further comprises at least two adjusting lines used for controlling the approaching angle of the pair of clamping parts, each adjusting line is folded into two strands after being movably connected with the clamping parts, and the near ends of the two strands of lines are movably arranged in the channel in a penetrating mode and connected with the near end of the pushing assembly. The two strands of wires of each adjusting wire are not arranged in the opposite channels on the opposite sides in a penetrating mode at the same time.

Description

Technical Field

[0001] The present invention relates to the technical field of interventional medical devices, and in particular to a valve repair system. Background Art

[0002] Mitral valve disease is a common disease among the elderly, including two common types: mitral regurgitation and mitral stenosis, of which mitral regurgitation is the most common. According to statistics, the incidence of mitral regurgitation in people over 75 years old is as high as 10%. Mild mitral regurgitation generally has no effect on normal life, while moderate to severe or severe mitral regurgitation requires interventional treatment. Traditional surgical treatment is open-chest treatment. With the support of an extracorporeal circulation machine, the heart is opened to repair or replace the valve, but high-risk patients cannot tolerate it. The rise of interventional treatment in recent years has brought hope to high-risk patients with mitral regurgitation. Interventional treatment generally involves delivering the device to the lesion site through a catheter to repair or replace the valve. Abbott MitraClip and Edwards PASCAL are typical representatives. MitraClip was promoted clinically earlier. The mechanical working principle of the clip design is a four-bar structure. The clip is sent from the atrium down to the vicinity of the mitral valve through the femoral vein puncture and the atrial septum puncture via a catheter, clamping and fixing the free edges of the anterior and posterior leaflets, and clamping the mitral valve into a double hole with the clip, so that the leaflets are well aligned at the end of contraction and reflux is reduced. Edward PASCAL has a completely different mechanical working principle from MitraClip. Its design is similar to the clip opening and closing mechanism of the diamond folding structure. The leaflet capture clamp force and leaflet fixing force of PASCAL are both the elastic retraction force of the pre-formed metal. It is also through femoral vein puncture, transcatheter atrial septal puncture, and the mitral valve is clamped into a double hole with a clip.

[0003] Both PASCAL and MitraClip use a structure that uses two pull wires to control a pair of elastic clamp arms located inside to facilitate the delivery and clamping of tissues. Figure 1 As shown, the existing scheme adopts a scheme in which a single double-strand wire 30' passes through a pair of side holes 21'. Although this scheme can use the pulling clamp arm to compress the spacer located in the middle to a smaller width to avoid the problem of large transportation resistance or difficult recovery, it has the following defects: first, the two pull wires are together and are easy to entangle, which increases the resistance to wire withdrawal or makes it impossible to withdraw the wire normally; second, the angle formed by the two pull wires at the contact position with the clamp arm pull ring is small. When the wire is withdrawn after the operation, the shear force between the pull wire and the clamp arm pull ring will be large, the damage to the pull wire will be more obvious, and there will be a risk of failure; third, the action of the clamp arm is greatly affected by the friction resistance between the pull wire and the edge of the hole, and the friction will also cause certain damage to the pull wire; these defects lead to greater safety hazards and potential risks in the valve repair system. Summary of the invention

[0004] Based on this, the present invention provides a valve repair system, aiming to improve the safety of the valve repair system.

[0005] To achieve this object, the present invention adopts the following technical solutions:

[0006] The present invention provides a valve repair system, comprising a valve repair device and a delivery device for delivering the valve repair device to a preset position; wherein:

[0007] The valve repair device comprises: at least one pair of clamping parts and at least one pair of elastic clamping parts; the pair of clamping parts can move between an open position and a closed position, and the pair of clamping parts are located between the pair of clamping parts and are opposite to the pair of clamping parts respectively; in a natural state, the pair of clamping parts are away from each other and are respectively in contact with the clamping parts opposite to them;

[0008] The delivery device at least comprises a push assembly, the push assembly comprises a push catheter, the valve repair device is detachably connected to the distal end of the push catheter, the push catheter is provided with a channel running through the proximal end and the distal end thereof, and the channel is provided in plurality in the circumferential direction of the push catheter, wherein the plurality of channels at least comprises two opposite channels which are respectively opposite to the two clamping parts in the axial direction;

[0009] The valve repair system also includes at least two adjustment wires for controlling the angle at which a pair of clamping parts approach each other, each of the adjustment wires being movably connected to a clamping part, and the adjustment wires are folded in half to form two strands after being movably connected to the clamping part, and the proximal ends of the two strands can be movably passed through the channel and connected to the proximal end of the pushing component; wherein the two strands of each adjustment wire are not simultaneously passed through a relative channel on the opposite side.

[0010] In one embodiment, the plurality of channels include at least one middle channel located between two of the opposing channels.

[0011] In one embodiment, the proximal end of one of the two strands of each adjustment wire is passed through the relative channel on the opposite side, and the proximal end of the other strand is passed through one of the middle channels; or, the proximal ends of the two strands of each adjustment wire are respectively passed through the two middle channels.

[0012] In one embodiment, the proximal ends of the two strands of each of the adjustment wires are simultaneously inserted into one of the middle channels.

[0013] In one embodiment, the proximal ends of the two strands of each adjusting wire are simultaneously inserted into the relative channels opposite thereto.

[0014] In one embodiment, the valve repair system further includes a limiter, which is disposed on the proximal side of the valve repair device and / or the distal side of the push catheter, and the adjustment line can movably pass through the limiter in the axial direction, and the limiter is used to form a radial constraint on a part of the adjustment line.

[0015] In one embodiment, the valve repair device also includes a support rod and an elastic spacer arranged between a pair of the clamping parts, the clamping part is connected to the distal end of the support rod and can be opened and closed relative to the support rod, the spacer is sleeved on the support rod, and the proximal end of the support rod extends out of the proximal end of the spacer and is provided with a first connecting part at its proximal end, and a second connecting part is provided at the distal end of the push catheter, the first connecting part and the second connecting part are detachably connected, and the limiting member is provided on the outer wall of the first connecting part and / or the second connecting part.

[0016] In one embodiment, the limiting member includes a limiting ring sleeved on the outer wall of the first connecting part and / or the second connecting part, the limiting ring is provided with a first through hole for the adjustment line to pass through, and / or a first gap for the adjustment line to pass through is provided between the inner wall of the limiting ring and the outer wall of the first connecting part and / or the second connecting part; or,

[0017] The limiting member includes a plurality of limiting seats arranged on the outer wall of the first connecting part and / or the second connecting part, the limiting seat is provided with a second through hole for the adjustment line to pass through, and / or a second gap for the adjustment line to pass through is provided between the inner wall of the limiting seat and the outer wall of the first connecting part and / or the second connecting part.

[0018] In one embodiment, a plurality of the first through holes or the second through holes are provided, and two strands of each adjustment wire pass through different first through holes or the second through holes respectively.

[0019] In one embodiment, at least a partial aperture at the distal end of the first through hole or the second through hole is smaller than the aperture at the proximal end of the first through hole or the second through hole, so that a supporting pulling point is formed on the outer side of the inner wall at the distal end of the first through hole or the second through hole.

[0020] The regulating wire in the valve repair system of the present invention adopts a new threading method, avoiding the potential risks caused by a single double strand threading through a hole. When the limiter is set, the limiter can form a local radial constraint on the regulating wire, which can give the regulating wire a pulling force toward the central axis, and can quickly and effectively compress the spacer to a smaller width, avoiding the problems of large transport resistance and difficult recovery. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1It is a partial schematic diagram of threading of the pull wire in the existing valve repair system;

[0022] Figure 2 It is a partial schematic diagram of the valve repair system of the present invention;

[0023] Figure 3 A schematic diagram of threading an adjustment line of the valve repair system of the present invention;

[0024] FIG. 4( a ) is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0025] FIG4( b ) is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0026] FIG4( c ) is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0027] FIG4( d ) is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0028] Figure 5 This is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0029] Figure 6 This is a schematic diagram of threading another adjustment line of the valve repair system of the present invention;

[0030] Figure 7 It is a schematic diagram of the adjustment line of the valve repair system of the present invention passing through the limiting ring provided on the second connecting part;

[0031] Figure 8 It is a schematic diagram of the adjustment line of the valve repair system of the present invention passing through the limiting ring provided on the first connecting part;

[0032] Fig. 9 It is a schematic diagram of the adjustment line of the valve repair system of the present invention passing through the limit seat;

[0033] Fig.10 It is a schematic diagram of a plurality of second through holes provided on the limiting seat of the valve repair system of the present invention;

[0034] Fig.11 It is a partial cross-sectional schematic diagram of the adjustment wire of the valve repair system of the present invention passing through the exemplary first through hole / second through hole. DETAILED DESCRIPTION

[0035] In order to make the purpose, technical solutions and advantages of the present invention more clearly understood, exemplary embodiments of the present disclosure will be described in more detail below with reference to the accompanying drawings. Although exemplary embodiments of the present disclosure are shown in the accompanying drawings, it should be understood that the present disclosure can be implemented in various forms and should not be limited by the embodiments described herein. On the contrary, these embodiments are provided in order to enable a more thorough understanding of the present disclosure and to fully convey the scope of the present disclosure to those skilled in the art.

[0036] It should be understood that the terms used herein are only for the purpose of describing specific example embodiments and are not intended to be limiting. Unless the context clearly indicates otherwise, the singular forms "one", "an" and "said" as used herein may also be meant to include plural forms. The terms "include", "comprise", "contain", and "have" are inclusive, and therefore specify the existence of stated features, steps, operations, elements and / or parts, but do not exclude the existence or addition of one or more other features, steps, operations, elements, parts, and / or combinations thereof. The method steps, processes, and operations described herein are not interpreted as necessarily requiring them to be performed in the specific order described or illustrated, unless the execution order is clearly indicated. It should also be understood that additional or alternative steps may be used.

[0037] Although the terms first, second, third, etc. can be used in the text to describe multiple elements, components, regions, layers and / or sections, these elements, components, regions, layers and / or sections should not be limited by these terms. These terms can only be used to distinguish an element, component, region, layer or section from another region, layer or section. Unless the context clearly indicates, terms such as "first", "second" and other numerical terms do not imply order or sequence when used in the text. Therefore, the first element, component, region, layer or section discussed below can be referred to as the second element, component, region, layer or section without departing from the teaching of the example embodiments.

[0038] For ease of description, spatial relative terms may be used herein to describe the relationship of one element or feature relative to another element or feature as shown in the figure, such as "inside", "outside", "inner side", "outer side", "below", "below", "above", "above", etc. Such spatial relative terms are intended to include different orientations of the device in use or operation in addition to the orientation depicted in the figure. For example, if the device in the figure is turned over, then the elements described as "below other elements or features" or "below other elements or features" will subsequently be oriented as "above other elements or features" or "above other elements or features". Therefore, the example term "below..." can include both upper and lower orientations. The device can be oriented otherwise (rotated 90 degrees or in other directions) and the spatial relative descriptors used in the text are interpreted accordingly.

[0039] In addition, it should be noted that in the present invention, the end of the medical device implanted in the human or animal body or the conveyor for conveying the medical device that is closer to the operator is defined as the "proximal end", and the end that is farther from the operator is defined as the "distal end", and the "proximal end" and "distal end" of any component of the medical device or conveyor are defined based on this principle. "Axial" refers to the length direction of the medical device when being conveyed, and "radial" refers to the direction of the medical device perpendicular to its "axial direction", and the "axial" and "radial" of any component of the medical device are defined based on this principle.

[0040] Please refer to Figure 2 and Figure 3 As shown, the present invention exemplarily provides a valve repair system 100, which includes a valve repair device 10, a delivery device for delivering the valve repair device 10 to a preset position, and at least two adjustment wires 30 for controlling a pair of elastic clamping parts 12 of the valve repair device 10, the two adjustment wires 30 respectively pulling the two clamping parts 12 to control the angle at which the pair of clamping parts 12 approach each other.

[0041] Specifically, Figure 2 As shown, the valve repair device 10 includes at least one pair of clamping parts 11 and at least one pair of elastic clamping parts 12. The pair of clamping parts 11 and the pair of clamping parts 12 are symmetrically arranged relative to the axis of the valve repair device 10. The pair of clamping parts 11 can move between an open position and a closed position. The pair of clamping parts 12 are located between the pair of clamping parts 11 and are respectively opposite to the pair of clamping parts 11; in a natural state, that is, when no external force is applied, that is, when the adjustment line 30 does not pull the clamping part 12, the pair of clamping parts 12 are separated from each other through a predetermined shape, and are respectively fitted with the clamping parts 11 opposite thereto, and the leaflet tissue is clamped between the clamping parts 12 and the clamping parts 11.

[0042] Combination Figure 2 and Figure 3 As shown, the delivery device at least includes a push assembly 20, and the push assembly 20 includes a push catheter 21. The valve repair device 10 is detachably connected to the distal end of the push catheter 21. The tube wall of the push catheter 21 is provided with a channel 22 that runs through the proximal end and the distal end thereof. There are multiple channels 22, and the multiple channels 22 are spaced apart along the circumferential direction of the tube wall of the push catheter 21, wherein the multiple channels 22 include at least two relative channels 221 that are axially opposite to the two clamping parts 12, respectively. It should be noted that the multiple in the present invention refers to two or more, and the axially opposite in the present invention refers to the relative channels 221 being within the axial projection area of ​​the clamping part 12.

[0043] Each adjusting wire 30 is movably connected to a clamping portion 12. The movably connected wire 30 may be passed through a perforation on the clamping portion 12 or a connecting member (such as a pull ring) on ​​the clamping portion 12. After the adjusting wire 30 is movably connected to the clamping portion 12, it is folded in half to form two strands. Figure 2 or Figure 3 The two strands shown are respectively the first strand 31 and the second strand 32. The proximal ends of the first strand 31 and the second strand 32 can be movably inserted into the channel 22 and connected to the proximal end of the pushing assembly 20. When the adjusting wire 30 is pulled at the proximal end, the clamping portion 12 connected to the pulled adjusting wire 30 moves toward the middle. In this embodiment, the two strands of each adjusting wire 30 (i.e., the first strand 31 and the second strand 32) are not simultaneously inserted into a relative channel 221 on the opposite side. It should be noted that the two strands of each adjusting wire 30 (i.e., the first strand 31 and the second strand 32) described in the present invention are not simultaneously inserted into a relative channel 221 on the opposite side. Figure 1 The scheme shown.

[0044] Furthermore, the plurality of channels 22 at least include a middle channel 222 located between two opposite channels 221 . That is, the plurality of channels 22 include opposite channels 221 and a middle channel 222 located between the two opposite channels 221 .

[0045] When the middle channel 222 is provided, as an embodiment, the proximal end of one of the two strands of each adjustment wire 30 is passed through the opposite channel 221 on the opposite side, and the proximal end of the other strand is passed through one of the middle channels 222. Figure 2 and Figure 3As shown, the proximal end of the first strand 31 of the two strands is inserted into the relative channel 221 on the opposite side, and the proximal end of the second strand 32 is inserted into one of the intermediate channels 222. It should be noted that when there are multiple intermediate channels 222, the other strand of the regulating wire can be selectively passed through one of the intermediate channels 222. This embodiment adopts the scheme of single strand and single hole on the opposite side and the side. On the one hand, when the regulating wire 30 is tightened, the spacer 13 can be compressed to a smaller width by the clamping part 12, and the problems of large conveying resistance and difficult recovery can be avoided during transportation and recovery. On the other hand, the two strands of regulating wire are perforated separately to avoid the entanglement of the two strands of wire. At the same time, the angle formed by the two strands of regulating wire at the contact position with the clamping part is increased, and the shear force is significantly reduced when the wire is withdrawn after the operation, and the regulating wire is not significantly damaged. In addition, the single-line single-hole threading also reduces the occupancy of the cavity and reduces the difficulty of sterilization; and in this scheme, the influence and wear caused by friction resistance are reduced.

[0046] When the intermediate channel 222 is provided, as another embodiment, the proximal ends of the two strands of each adjustment line 30 are respectively passed through the two intermediate channels 222. Figures 4(a) to 4(d) As shown, the proximal end of the first strand 31 of the two strands of wire is inserted into the middle channel 222 on one side, while the proximal end of the second strand 32 is inserted into the middle channel 222 on the opposite side. It should be noted that when there are multiple middle channels 222, each adjustment wire can selectively pass through one of the middle channels 222. In the scheme of this embodiment, the angle formed by the two adjustment wires at the contact position with the clamping part is increased, and the shear force is significantly reduced when the wires are withdrawn after the operation, and the adjustment wires are not significantly damaged; and in this scheme, the influence and wear caused by friction resistance are reduced.

[0047] When the intermediate channel 222 is provided, as another embodiment, the proximal ends of the two strands of each adjustment line 30 are simultaneously passed through one of the intermediate channels 222. Figure 5 As shown, the proximal ends of the first strand 31 and the second strand 32 of the two strands are simultaneously passed through one of the intermediate channels 222. It should be noted that when there are multiple intermediate channels 222, the two adjustment wires can selectively pass through one of the intermediate channels 222. Preferably, in order to ensure the overall stability of the valve repair system 100, the intermediate channels 222 through which the two strands of the two adjustment wires 30 pass are symmetrically arranged. In the solution of this embodiment, when the clamping part is released from capture, the action of the clamping part is less affected by the friction resistance between the adjustment wire and the edge of the hole, and the wear caused is also reduced.

[0048] When the plurality of channels 22 include a relative channel 221 or include a relative channel 221 and a middle channel 222 located between the two relative channels 221, the proximal ends of the two strands of each adjustment line 30 are simultaneously inserted into the relative channel 221 opposite thereto. Figure 6As shown, the proximal ends of the first strand 31 and the second strand 32 of the two strands are simultaneously inserted into the relative channel 221 opposite thereto. When the intermediate channel 222 is provided, the provision of the intermediate channel 222 can reduce the overall weight of the valve repair system 100 on the one hand, which is conducive to ensuring the overall balance and stability, and can also serve as a backup passage on the other hand. In the scheme of this embodiment, when the clamping part is released from the capture, the action of the clamping part is less affected by the friction resistance between the adjustment line and the edge of the hole, and the wear caused is also reduced.

[0049] Reference Figure 7 to Figure 9 In order to facilitate transportation and recovery, based on any of the above embodiments, the valve repair system 100 of the present invention also includes a limiter, which is arranged on the proximal side of the valve repair device 10 and / or the distal side of the push catheter 21. The adjustment line 30 can movably pass through the limiter in the axial direction, and the limiter is used to form a radial constraint on the part of the adjustment line 30. When the adjustment line 30 passing through the limiter is tightened, the limiter can give the adjustment line 30 a restraining pulling force in the direction of the central axis, which can effectively and quickly bring a pair of clamping parts 12 closer to each other. When the valve repair device 10 includes an elastic spacer 13, the setting of the limiter can quickly and effectively compress the spacer 13 to a smaller width, and the problem of large transportation resistance or difficult recovery can be avoided during transportation and recovery. It should be noted that the setting of the limiter can be applied to any of the above embodiments and form a new solution with better effects.

[0050] Continue to refer to Figure 2 and Figure 7 to Figure 9 As shown, the valve repair device 10 also includes a support rod 14 and an elastic spacer 13 arranged between a pair of clamping parts 12, the clamping part 11 is connected to the distal end of the support rod 14 and can be opened and closed relative to the support rod 14, the spacer 13 is sleeved on the support rod 14, and the proximal end of the support rod 14 extends out of the proximal end of the spacer 13 and is provided with a first connecting part 141 at its proximal end, and a second connecting part 211 is provided at the distal end of the push catheter 21, the first connecting part 141 and the second connecting part 211 are detachably connected, and a limiting member is provided on the outer wall of the first connecting part 141 and / or the second connecting part 211.

[0051] As a setting method of the limiter, see Figure 7 As shown, the limiting member includes a limiting ring 41 which is sleeved on the outer wall of the second connecting part 211. In order to allow the adjustment line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a for the adjustment line 30 to pass through, and / or a first gap (not shown) for the adjustment line 30 to pass through is provided between the inner wall of the limiting ring 41 and the outer wall of the second connecting part 211.

[0052] or, see Figure 8As shown, the limiting member includes a limiting ring 41 which is sleeved on the outer wall of the first connecting part 141. In order to allow the adjustment line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a for the adjustment line 30 to pass through, and / or a first gap (not shown) is provided between the inner wall of the limiting ring 41 and the outer wall of the first connecting part 141 for the adjustment line 30 to pass through.

[0053] Alternatively, the limiting member includes a limiting ring 41 on the outer wall of the first connecting part 141 and sleeved on the outer wall of the second connecting part 211. In order to allow the adjustment line 30 to pass through, the limiting ring 41 is provided with a first through hole 40a for the adjustment line 30 to pass through, and / or a first gap (not shown) for the adjustment line 30 to pass through is provided between the inner wall of the limiting ring 41 and the outer walls of the first connecting part 141 and the second connecting part 211.

[0054] It should be understood that in the above-mentioned setting mode of the limiting member including the limiting ring 41, only the first through hole 40a or the first gap can be set for the adjustment line 30 to pass through, or the first through hole 40a and the first gap can be set at the same time for the adjustment line 30 to pass through.

[0055] As another way to set the limiter, see Fig. 9 As shown, the limiting member includes a plurality of limiting seats 42 arranged on the outer wall of the first connecting portion 141 and / or the second connecting portion 211, and the limiting seats 42 are provided with second through holes 40b through which the adjustment line 30 can pass, and / or a second gap (not shown) through which the adjustment line 30 can pass is provided between the inner wall of the limiting seat 42 and the outer wall of the first connecting portion 141 and / or the second connecting portion 211. Fig. 9 The limiting seat 42 is disposed on the first connection portion 141 , but is not limited thereto. The limiting seat 42 may also be disposed on the second connection portion 211 or disposed on both the first connection portion 141 and the second connection portion 211 .

[0056] In order to prevent the two strands of a single adjusting wire from getting tangled, a plurality of first through holes 40a or second through holes 40b are provided, and the plurality of through holes are arranged at intervals in the circumferential direction, and the two strands of each adjusting wire 30 pass through different first through holes 40a or second through holes 40b. Fig.10 As shown, two second through holes 40b are arranged on the limiting seat 42 at intervals in the circumferential direction, and the first strand 31 and the second strand 32 of the single adjustment wire 30 pass through the two second through holes 40b respectively, thereby avoiding entanglement of the two strands of wire.

[0057] Furthermore, at least a partial aperture at the distal end of the first through hole 40a or the second through hole 40b is smaller than the aperture at the proximal end of the first through hole 40a or the second through hole 40b, so that a support and pulling point is formed at the outer side of the inner wall at the distal end of the first through hole 40a or the second through hole 40b. It should be noted that the outer side of the inner wall refers to the inner wall side of the first through hole 40a or the second through hole 40b away from the axis of the valve repair system, rather than the outer side of the first connecting portion 141 and / or the second connecting portion 211. Fig.11 As shown, the aperture of the first through hole 40a or the second through hole 40b increases gradually from far to near, that is, Fig.11 In the S direction shown in FIG. 1 , the first through hole 40a or the second through hole 40b is arranged obliquely relative to the outer side of the inner wall of the valve repair system and relative to the axis of the valve repair system, and the aperture of the first through hole 40a or the second through hole 40b gradually increases, such as Fig.11 As shown in the figure, the aperture of the first through hole 40a or the second through hole 40b gradually increases from W1 at the distal end to W2. This arrangement allows an effective pulling point to be formed at the orifice at the distal end when the adjustment line 30 is pulled, so that the clamping portion can be quickly responded to and contracted, and the spacer 13 can be quickly compressed to a smaller width. At the same time, the aperture at the proximal end is large, which facilitates the sliding of the adjustment line 30.

[0058] Preferably, in order to reduce damage to the adjustment line 30, the opening at the distal end of the first through hole 40a or the second through hole 40b is rounded so that the edge opening at the distal end is flared outward, which prevents damage and facilitates the passage and withdrawal of the adjustment line.

[0059] The regulating wire in the valve repair system of the present invention adopts a new threading method, avoiding the potential risks caused by a single double strand threading through a hole. When the limiter is set, the limiter can form a local radial constraint on the regulating wire, which can give the regulating wire a pulling force toward the central axis, and can quickly and effectively compress the spacer to a smaller width, avoiding the problems of large transport resistance and difficult recovery.

[0060] The technical features of the above-described embodiments may be arbitrarily combined. To make the description concise, not all possible combinations of the technical features in the above-described embodiments are described. However, as long as there is no contradiction in the combination of these technical features, they should be considered to be within the scope of this specification.

[0061] The above-mentioned embodiments only express several implementation methods of the present invention, and the descriptions thereof are relatively specific and detailed, but they cannot be understood as limiting the scope of the invention patent. It should be pointed out that, for ordinary technicians in this field, several variations and improvements can be made without departing from the concept of the present invention, and these all belong to the protection scope of the present invention. Therefore, the protection scope of the patent of the present invention shall be subject to the attached claims.

Claims

1. A valve repair system, characterized in that: It comprises a valve repair device and a delivery device for delivering the valve repair device to a preset position; wherein, The valve repair device comprises: at least one pair of clamping parts and at least one pair of elastic clamping parts; the pair of clamping parts can move between an open position and a closed position, and the pair of clamping parts are located between the pair of clamping parts and are opposite to the pair of clamping parts respectively; in a natural state, the pair of clamping parts are away from each other and are respectively in contact with the clamping parts opposite to them; The delivery device at least comprises a push assembly, the push assembly comprises a push catheter, the valve repair device is detachably connected to the distal end of the push catheter, the push catheter is provided with a channel running through the proximal end and the distal end thereof, and the channel is provided in plurality in the circumferential direction of the push catheter, wherein the plurality of channels at least comprises two opposite channels which are respectively opposite to the two clamping parts in the axial direction; The valve repair system also includes at least two adjustment wires for controlling the angle at which a pair of clamping parts approach each other, each of the adjustment wires being movably connected to a clamping part, and the adjustment wires are folded in half to form two strands after being movably connected to the clamping part, and the proximal ends of the two strands can be movably passed through the channel and connected to the proximal end of the pushing component; wherein the two strands of each adjustment wire are not simultaneously passed through a relative channel on the opposite side.

2. The valve repair system according to claim 1, characterized in that: The plurality of channels also include at least one middle channel located between two of the opposing channels.

3. The valve repair system according to claim 2, characterized in that: The proximal end of one of the two strands of each adjusting wire is inserted into the relative channel on the opposite side, and the proximal end of the other strand is inserted into one of the middle channels.

4. The valve repair system according to claim 2, characterized in that: The proximal ends of the two strands of each adjusting wire are respectively inserted into the two middle channels; Alternatively, the proximal ends of the two strands of each adjusting wire are simultaneously inserted into one of the middle channels.

5. The valve repair system according to claim 1, characterized in that: The proximal ends of the two strands of each adjusting wire are simultaneously inserted into the relative channels opposite thereto.

6. The valve repair system according to any one of claims 1 to 5, characterized in that: The valve repair system also includes a limiter, which is arranged on the proximal side of the valve repair device and / or the distal side of the push catheter. The adjustment line can movably pass through the limiter in the axial direction, and the limiter is used to form a radial constraint on a part of the adjustment line.

7. The valve repair system according to claim 6, characterized in that: The valve repair device also includes a support rod and an elastic spacer arranged between a pair of the clamping parts, the clamping part is connected to the distal end of the support rod and can be opened and closed relative to the support rod, the spacer is sleeved on the support rod, and the proximal end of the support rod extends out of the proximal end of the spacer and is provided with a first connecting part at its proximal end, and a second connecting part is provided at the distal end of the push catheter, the first connecting part and the second connecting part are detachably connected, and the limiting part is provided on the outer wall of the first connecting part and / or the second connecting part.

8. The valve repair system according to claim 7, characterized in that: The limiting member comprises a limiting ring sleeved on the outer wall of the first connecting part and / or the second connecting part, the limiting ring is provided with a first through hole for the adjusting wire to pass through, and / or a first gap for the adjusting wire to pass through is provided between the inner wall of the limiting ring and the outer wall of the first connecting part and / or the second connecting part; or, The limiting member includes a plurality of limiting seats arranged on the outer wall of the first connecting part and / or the second connecting part, the limiting seat is provided with a second through hole for the adjustment line to pass through, and / or a second gap for the adjustment line to pass through is provided between the inner wall of the limiting seat and the outer wall of the first connecting part and / or the second connecting part.

9. The valve repair system according to claim 8, characterized in that: There are a plurality of the first through holes or the second through holes, and the two strands of each adjustment wire pass through different first through holes or the second through holes respectively.

10. The valve repair system according to claim 8, characterized in that: At least a partial aperture at the distal end of the first through hole or the second through hole is smaller than the aperture at the proximal end of the first through hole or the second through hole, so that a supporting pulling point is formed on the outer side of the inner wall at the distal end of the first through hole or the second through hole.

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