Drug delivery device

Abstract

The invention relates to the technical field of medical instruments, in particular to a drug delivery device which comprises a drug delivery head, a sealing plate and a piezoelectric ceramic piece. The dosing head is provided with a medicine containing cavity used for containing medicine liquid and a dosing channel communicated with the medicine containing cavity. The sealing plate is arranged in the dosing channel, a plurality of medicine outlet holes are formed in the sealing plate at intervals, the medicine outlet holes are configured to prevent medicine liquid from flowing out through surface tension when being not vibrated, so that the medicine liquid is prevented from flowing out, the piezoelectric ceramic piece is arranged in the dosing channel, the piezoelectric ceramic piece is connected to the dosing head, and the piezoelectric ceramic piece drives the sealing plate to vibrate. The medicine liquid is impacted by the sealing plate and flows out of the medicine outlet hole, the diameter of the medicine outlet hole is small, the medicine liquid can be atomized when the sealing plate impacts the medicine liquid, the structure of the medicine feeding device is simplified, the machining cost of the medicine feeding device is reduced, and popularization is facilitated.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, in particular to a drug delivery device. Background Art

[0002] As an important part of the human sensory system, the nose undertakes basic physiological functions such as smell and breathing. The structure of the nasal cavity is complex and directly connected to the external environment, making it easy to be damaged or infected. There is a special area in the nasal cavity called the olfactory fissure, which has an incomplete blood-brain barrier structure. Once the nasal cavity is damaged or infected, it may spread to other parts, causing the disease to spread.

[0003] The existence of the olfactory cleft also makes it possible to administer drugs through the nose-brain pathway for disease treatment and vaccine delivery. By utilizing the olfactory cleft, a special area with an incomplete blood-brain barrier structure, the drug can quickly enter the brain and avoid systemic circulation and first-pass effects. Whether it is for drug administration for nasal infection or for drug administration through the nose-brain pathway, drugs are administered through the nostrils using an internal nasal drug delivery device.

[0004] Most of the existing intranasal drug delivery devices need to be provided with an atomizing head and a drug delivery pump for passing the drug into the atomizing pump. The intranasal drug delivery devices have a complex structure and high cost, which is not conducive to promotion. Summary of the invention

[0005] The technical problem to be solved by the present invention is that the existing intranasal drug delivery device has a complex structure and high cost, which is not conducive to promotion.

[0006] In order to solve the above technical problems, the object of the present invention is to provide a drug delivery device, including a drug delivery head, a sealing plate and a piezoelectric ceramic sheet;

[0007] The drug delivery head has a drug-containing cavity and a drug delivery channel, wherein the drug-containing cavity is used to contain drug solution, one end of the drug delivery channel is connected to the drug-containing cavity, and the other end is connected to the outside;

[0008] The sealing plate is arranged in the drug delivery channel, and the sealing plate has a plurality of drug outlet holes, and each of the drug outlet holes is configured to: prevent the drug solution from flowing out by surface tension when not vibrated;

[0009] The piezoelectric ceramic sheet is arranged in the drug delivery channel, the piezoelectric ceramic sheet connects the drug delivery head and the sealing plate, and the piezoelectric ceramic sheet drives the sealing plate to vibrate, so that the drug solution is impacted by the sealing plate and flows out from the drug outlet.

[0010] As a preferred embodiment, the inner wall of the drug administration channel is provided with an annular groove, the piezoelectric ceramic sheet is an annular sheet with a through hole in the middle, the sealing plate and the piezoelectric ceramic sheet are both arranged in the annular groove, and each of the drug outlet holes is arranged opposite to the through hole in the axial direction of the drug administration channel.

[0011] As a preferred embodiment, the annular groove has a first groove wall and a second groove wall that are arranged opposite to each other in the axial direction of the medication channel, and the piezoelectric ceramic sheet is a telescopically deformable piezoelectric ceramic sheet, one end of the telescopically deformable piezoelectric ceramic sheet is connected to the first groove wall, and the other end is connected to the sealing plate; the sealing plate and the second groove wall are arranged opposite to each other in the axial direction of the medication channel.

[0012] As a preferred embodiment, the drug delivery device also includes a first elastic ring, which is arranged in the annular groove and located in the gap between the sealing plate and the second groove wall, one end of the first elastic ring abuts against the sealing plate, and the other end abuts against the second groove wall.

[0013] As a preferred solution, the piezoelectric ceramic sheet is a bending-deformed piezoelectric ceramic sheet, and the bending-deformed piezoelectric ceramic sheet is bonded and fixed to the sealing plate.

[0014] As a preferred embodiment, the annular groove has a first groove wall and a second groove wall that are arranged opposite to each other in the axial direction of the drug delivery channel, and the drug delivery device also includes a second elastic ring and a third elastic ring arranged in the annular groove; in the axial direction of the annular groove, the first groove wall, the second elastic ring, the bending deformed piezoelectric ceramic sheet, the sealing plate, the third elastic ring and the second groove wall are abutted in sequence.

[0015] As a preferred solution, the medicine outlet hole is a circular hole, and the diameter of the medicine outlet hole is greater than or equal to 0.2 microns and less than or equal to 200 microns.

[0016] As a preferred solution, the drug delivery device further comprises a sealing cover, which is detachably connected to the drug delivery head and seals the drug delivery end of the drug delivery channel.

[0017] As a preferred embodiment, the drug delivery device also includes a drug delivery device body, in which a circuit board is provided, the drug delivery device body has a threaded hole, in which a first conductive part electrically connected to the circuit board is provided; the drug delivery head has a threaded joint, and the threaded joint has a second conductive part electrically connected to the piezoelectric ceramic sheet, and the threaded joint is threadedly matched in the threaded hole so that the first conductive part can abut against the second conductive part.

[0018] As a preferred embodiment, the drug delivery device further comprises a sealing ring, the drug delivery head comprises a docking platform protruding outward from the threaded joint, the sealing ring is sleeved on the outside of the threaded joint, and two sides of the sealing ring respectively abut against the docking platform and the outer peripheral edge of the threaded hole.

[0019] Compared with the prior art, the present invention has the following beneficial effects:

[0020] The drug delivery device of the present invention comprises a drug delivery head, a sealing plate and a piezoelectric ceramic sheet; the drug delivery head comprises a drug containing cavity for containing drug liquid and a drug delivery channel connected to the drug containing cavity; the sealing plate is arranged in the drug delivery channel, and a plurality of drug outlet holes are arranged on the sealing plate at intervals, and each drug outlet hole is configured to prevent the drug liquid from flowing out by surface tension when not vibrated, thereby avoiding the drug liquid from flowing out; the piezoelectric ceramic sheet is arranged in the drug delivery channel, and the piezoelectric ceramic sheet is connected to the drug delivery head; the piezoelectric ceramic sheet drives the sealing plate to vibrate, so that the drug liquid is impacted by the sealing plate and flows out from the drug outlet hole; the aperture of the drug outlet hole is small, and the sealing plate impacting the drug liquid can atomize the drug liquid; in the drug delivery device of the present invention, the piezoelectric ceramic sheet directly drives the sealing plate to vibrate; when the drug delivery device is not in use, the sealing plate realizes the sealing of the drug liquid; when the drug delivery device is in use, the sealing plate realizes the effects of drug delivery and atomization, which greatly simplifies the structure of the drug delivery device, reduces the processing cost of the drug delivery device, and is conducive to promotion. BRIEF DESCRIPTION OF THE DRAWINGS

[0021] Figure 1 is an axonometric view of the drug delivery device of the present invention;

[0022] Figure 2 is a cross-sectional view of the drug delivery device of the present invention;

[0023] Figure 3 is a three-dimensional cross-sectional view of the drug delivery device of the present invention;

[0024] Figure 4 for the explosion of the drug delivery device of the present invention;

[0025] Figure 5 This is a schematic diagram of the structure of the drug delivery head;

[0026] Figure 6 A schematic diagram of the structure of the drug delivery head when the piezoelectric ceramic sheet is a bent and deformed piezoelectric ceramic sheet;

[0027] In the figure, 1, drug delivery head, 11, main body, 111, drug holding cavity, 112, drug delivery channel, 113, annular groove, 1131, first groove wall, 1132, second groove wall, 1133, bottom wall, 12, joint part, 121, columnar part, 122, threaded electrode, 1221, second conductive part, 2, sealing plate, 21, drug delivery hole, 3, piezoelectric ceramic sheet, 31, through hole, 41, first elastic ring, 42, second elastic ring, 43, third elastic ring, 5, sealing cover, 6, drug delivery device body, 61, circuit board, 62, battery, 63, booster, 64, first conductive part, 65, threaded hole, 7, sealing ring, 8, drug loading barrel. DETAILED DESCRIPTION

[0028] The specific implementation of the present invention is further described in detail below in conjunction with the accompanying drawings and examples. The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention.

[0029] In the description of the present invention, it should be understood that the orientation or positional relationship indicated by the terms "upper", "lower", "left", "right", "top", "bottom", etc. is based on the orientation or positional relationship shown in the accompanying drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation of the present invention. It should be understood that the terms "first", "second", etc. are used in the present invention to describe various information, but such information should not be limited to these terms, which are only used to distinguish the same type of information from each other. For example, without departing from the scope of the present invention, the "first" information may also be referred to as the "second" information, and similarly, the "second" information may also be referred to as the "first" information.

[0030] like Figures 1 to 6As shown, the drug delivery device of the present invention is characterized in that it includes a drug delivery head 1, a sealing plate 2 and a piezoelectric ceramic piece 3; the drug delivery head 1 has a drug containing cavity 111 and a drug delivery channel 112, the drug containing cavity 111 is used to contain drug liquid, one end of the drug delivery channel 112 is connected to the drug containing cavity 111, and the other end is connected to the outside; the sealing plate 2 is arranged in the drug delivery channel 112, and a plurality of drug outlet holes are arranged on the sealing plate 2 at intervals, and each drug outlet hole is configured to: prevent the drug liquid from flowing out by surface tension when not vibrated; the piezoelectric ceramic piece 3 is arranged in the drug delivery channel 112, the piezoelectric ceramic piece 3 connects the drug delivery head 1 and the sealing plate 2, and the piezoelectric ceramic piece 3 drives the sealing plate 2 to vibrate, so that the drug liquid is impacted by the sealing plate 2 and flows out from the drug outlet hole. The design of the medicine outlet hole utilizes the characteristics of liquid surface tension. In a non-vibrating state, the medicine liquid will not flow out on its own, thus achieving sealing of the medicine liquid. The piezoelectric ceramic piece 3 is connected to the drug delivery head 1 and the sealing plate 2. By vibrating the sealing plate 2, the medicine liquid is stimulated to be impacted and sprayed out from the medicine outlet hole. The sealing plate 2 realizes the effects of drug delivery and atomization, which greatly simplifies the structure of the drug delivery device, reduces the processing cost of the drug delivery device, and at the same time ensures the accuracy of drug delivery, which is conducive to promotion.

[0031] Among them, the inner side wall of the drug administration channel 112 is provided with an annular groove 113, the piezoelectric ceramic sheet 3 is an annular sheet with a through hole 31 in the middle, the sealing plate 2 and the piezoelectric ceramic sheet 3 are both arranged in the annular groove 113, and each drug outlet hole is arranged opposite to the through hole 31 in the axial direction of the drug administration channel 112. The piezoelectric ceramic sheet 3 can be arranged at the end of the sealing plate 2 facing the drug cavity 111, or the piezoelectric ceramic sheet 3 can be arranged at the end of the sealing plate 2 facing away from the drug cavity 111. The annular groove 113 forms an installation space for installing the sealing plate 2 and the piezoelectric ceramic sheet 3, which is convenient for the installation and fixation of the piezoelectric ceramic sheet 3 and the sealing plate 2. The liquid medicine in the drug cavity 111 flows out of the drug administration head 1 through the through hole 31 and the drug outlet hole.

[0032] Among them, the notch of the annular groove 113 faces the center of the drug administration channel 112, and the annular groove 113 has a first groove wall 1131 and a second groove wall 1132 arranged opposite to each other in the axial direction of the drug administration channel 112, and the annular groove 113 also has a bottom wall 1133 opposite to the notch. In some embodiments of the present invention, the piezoelectric ceramic sheet 3 is a telescopic deformable piezoelectric ceramic sheet, the thickness direction of the piezoelectric ceramic sheet 3 is arranged along the axis of the annular groove 113, the polarization direction of the telescopic deformable piezoelectric ceramic sheet is arranged along its own thickness direction, and the direction of the external electric field is the same or opposite to the polarization direction, so as to realize the thickening or thinning of the telescopic deformable piezoelectric ceramic sheet in its own thickness direction and the axial direction of the annular groove 113, thereby driving the sealing plate 2 to reciprocate along the axis of the annular groove 113, one end of the telescopic deformable piezoelectric ceramic sheet is connected to the first groove wall 1131, and the other end is connected to the sealing plate 2, and the sealing plate 2 and the second groove wall 1132 are arranged relatively spaced apart in the axial direction of the drug administration channel 112.

[0033] In some embodiments of the present invention, the drug delivery device further comprises a first elastic ring 41, which is disposed in the annular groove 113 and is located in the gap between the sealing plate 2 and the second groove wall 1132, with one end of the first elastic ring 41 abutting against the sealing plate 2, and the other end abutting against the second groove wall 1132. The first elastic ring 41 not only improves the sealing performance between the sealing plate 2 and the groove wall of the annular groove 113 to prevent the drug solution from flowing out, but also after the first elastic ring 41 is set, it is not necessary to fix the telescopic deformation piezoelectric ceramic sheet on the first groove wall 1131, nor is it necessary to fix the sealing plate 2 on the piezoelectric ceramic sheet 3. One end of the telescopic deformation piezoelectric ceramic sheet abuts on the first groove wall 1131 and the other end abuts on the sealing plate 2. When the telescopic deformation piezoelectric ceramic sheet thickens, the telescopic deformation piezoelectric ceramic sheet pushes the sealing plate 2 so that the sealing plate 2 compresses the first elastic ring 41. When the telescopic deformation piezoelectric ceramic sheet becomes thinner, the elastic force of the first elastic ring 41 drives the sealing plate 2 to always abut on the telescopic deformation piezoelectric ceramic sheet to achieve the reset of the sealing plate 2. The setting of the first elastic ring 41 not only improves the sealing effect of the drug delivery head 1, but also simplifies the assembly process of the drug delivery head 1, improves the processing efficiency of the drug delivery head 1, and reduces the processing cost of the drug delivery head 1.

[0034] In some embodiments of the present invention, the first elastic ring 41 may not be provided, and the sealing plate 2 is bonded to one end of the telescopically deformable piezoelectric ceramic sheet, and the other end of the telescopically deformable piezoelectric ceramic sheet is bonded to the first groove wall 1131 .

[0035] In some embodiments of the present invention, the piezoelectric ceramic sheet 3 is a bending-deformed piezoelectric ceramic sheet, which includes a substrate layer with higher flexibility, a first piezoelectric layer arranged on one side of the substrate layer, and a second piezoelectric layer arranged on the other side of the substrate. When an alternating electric field is applied to the first piezoelectric layer and the second piezoelectric layer, one of the first piezoelectric layer and the second piezoelectric layer is extended and the other is shortened, so that the bending-deformed piezoelectric ceramic sheet can be bent and deformed. The deformation mode of the bending-deformed piezoelectric ceramic sheet is similar to the vibration of the drum surface when the drum surface is struck. The bending-deformed piezoelectric ceramic sheet is fitted and fixed to the sealing plate 2, thereby driving the sealing plate 2 to produce synchronous vibration, wherein the sealing plate 2 is a sheet body with good toughness, such as a spring steel sheet or a stainless steel sheet.

[0036] Furthermore, when the piezoelectric ceramic sheet 3 is set as a bending-deformed piezoelectric ceramic sheet 3, the drug delivery device further includes a second elastic ring 42 and a third elastic ring 43 arranged in the annular groove 113; in the axial direction of the annular groove 113, the first groove wall 1131, the second elastic ring 42, the bending-deformed piezoelectric ceramic sheet, the sealing plate 2, the third elastic ring 43 and the second groove wall 1132 are abutted in sequence. The setting of the second elastic ring 42 and the third elastic ring 43 not only improves the sealing effect of the drug delivery head 1, but also enables the positions of the bending-deformed piezoelectric ceramic sheet and the sealing plate 2 to always remain in the middle of the annular groove 113, so that the overall structure of the drug delivery head 1 is stable and not loose, and avoids the reduction in the texture of the drug delivery device caused by the shaking of the sealing plate 2 and the bending-deformed piezoelectric ceramic sheet in the annular groove 113.

[0037] In order to ensure the sealing effect and the liquid discharge effect, the aperture of the medicine discharge hole should be neither too large nor too small. In this embodiment, the medicine discharge hole is a circular hole, and the diameter of the medicine discharge hole is greater than or equal to 0.2 microns and less than or equal to 200 microns. In other embodiments of the present invention, the medicine discharge hole can be a hole body of other shapes such as a rectangular hole and a polygonal hole. It is sufficient to ensure that the medicine liquid will not flow out by itself when the piezoelectric ceramic sheet 3 is in a non-vibrating state, and the medicine liquid can flow out smoothly when the piezoelectric ceramic sheet 3 is in a vibrating state. The vibration frequency and vibration amplitude of the piezoelectric ceramic sheet 3 can be adjusted by adjusting the number of layers of the piezoelectric ceramic sheet 3 and the voltage applied to the piezoelectric ceramic sheet 3 to ensure the liquid discharge effect.

[0038] In this embodiment, the drug delivery device further includes a sealing cover 5, which is detachably connected to the drug delivery head 1, and the sealing cover 5 seals the drug delivery end of the drug delivery channel 112. The sealing cover 5 may be an elastic plug or a threaded cover, and the sealing cover 5 blocks the drug delivery end of the drug delivery channel 112, so that the drug delivery channel 112 between the drug delivery end and the sealing plate 2 is not connected to the atmospheric pressure, which increases the resistance of the drug delivery hole to the drug solution, further improves the sealing effect of the drug delivery device, and the sealing cover 5 can prevent the sealing plate 2 from being contaminated by impurities in the air, and the sealing cover 5 can be removed before use.

[0039] In this embodiment, the drug delivery device also includes a drug delivery device body 6, in which a circuit board 61 is provided, and the drug delivery device body 6 has a threaded hole 65, in which a first conductive part 64 electrically connected to the circuit board 61 is provided; the drug delivery head 1 has a threaded joint, and the threaded joint has a second conductive part 1221 electrically connected to the piezoelectric ceramic sheet 3, and the threaded joint is threadedly matched in the threaded hole 65 so that the first conductive part 64 can abut against the second conductive part 1221.

[0040] Specifically, the drug delivery head 1 includes a joint portion 12 and a main body portion 11, a drug containing cavity 111 and a drug delivery channel 112 are arranged in the main body portion 11, the drug delivery channel 112 and the drug containing cavity 111 are both circular hole structures, the joint portion 12 includes a columnar portion 121 and a threaded electrode 122, the columnar portion 121 is fixed to the main body portion 11, and the threaded electrode 122 is fixedly sleeved on the outside of the columnar portion 121 to form a threaded joint.

[0041] In this embodiment, in order to facilitate the assembly of the piezoelectric ceramic sheet 3 and the sealing plate 2, the drug delivery head 1 adopts a half-structure, and the drug delivery head 1 is divided into two semi-finished products along the axis of the drug delivery channel 112 and the drug holding cavity 111. During assembly, the two semi-finished products are matched and fixed to form the drug delivery head 1. The two semi-finished products can be positioned by positioning pins, and sealed and fixed by bonding. Among them, the drug holding cavity 111 can be directly processed inside the main body 11, or an installation cavity can be processed inside the main body, and a drug loading barrel 8 is placed in the installation cavity, and the barrel mouth of the drug loading barrel 8 is set toward the sealing plate 2, so as to facilitate the adjustment of the size of the drug loading barrel 8 according to the amount of medicine used. In this embodiment, in order to facilitate the installation of the circuit board 61, the battery 62 and the booster 63, the structure of the drug delivery device body 6 also adopts a half-structure.

[0042] In this embodiment, the drug delivery head 1 and the drug delivery device body 6 are conveniently disassembled by means of the threaded joint and the threaded hole 65. The drug delivery head 1 has a low cost. When administering the drug to the nasal cavity, the drug delivery head 1 needs to be inserted into the nasal cavity. The drug delivery head 1 can be used as a disposable item or for special use by one person only, thus avoiding the risk of cross infection. The drug delivery device body 6 can be reused.

[0043] In this embodiment, a circuit board 61, a battery 62 and a booster 63 are provided in the drug delivery device body 6. The battery 62 is connected to the circuit board 61 through a wire, the circuit board 61 is connected to the booster 63 through a wire, and the booster 63 is connected to the second conductive part 1221 through a wire. After the threaded joint is assembled in the threaded hole 65, the first conductive part 64 and the second conductive part 1221 are in contact and pressed against each other to form a loop. The electrical signal boosted by the booster 63 is transmitted to the piezoelectric ceramic sheet 3, causing the piezoelectric ceramic sheet 3 to generate high-frequency vibration. For ease of manipulation, in this embodiment, a wireless receiving device electrically connected to the circuit board 61 is also provided in the drug delivery device body 6, and drug delivery is controlled by a wireless transmitting device arranged outside the drug delivery device.

[0044] In some embodiments of the present invention, the drug delivery device further includes a sealing ring 7, the drug delivery head 1 has a docking platform protruding to the outside of the threaded joint, the sealing ring 7 is sleeved on the outside of the threaded joint, and the two sides of the sealing ring 7 respectively abut against the docking platform and the outer peripheral edge of the threaded hole 65. Specifically, the portion of the body 11 protruding from the outside of the threaded joint forms the docking platform, and the provision of the sealing ring 7 improves the sealing performance of the drug delivery device body 6 and the drug delivery head 1, and ensures the safety of the electrical connection between the first conductive part 64 and the second conductive part 1221.

[0045] In summary, the drug delivery device of the present invention comprises a drug delivery head 1, a sealing plate 2 and a piezoelectric ceramic piece 3; the drug delivery head 1 has a drug storage cavity 111 for containing a drug solution and a drug delivery channel 112 connected to the drug storage cavity 111; the sealing plate 2 is arranged in the drug delivery channel 112, and a plurality of drug outlet holes are arranged on the sealing plate 2 at intervals, and each drug outlet hole is configured to prevent the drug solution from flowing out by surface tension when not vibrated, thereby avoiding the drug solution from flowing out, and the piezoelectric ceramic piece 3 is arranged in the drug delivery channel 112, the piezoelectric ceramic piece 3 is connected to the drug delivery head 1, and the piezoelectric ceramic piece 3 is arranged in the drug delivery channel 112. The sheet 3 drives the sealing plate 2 to vibrate, so that the medicine liquid is impacted by the sealing plate 2 and flows out from the medicine outlet. The aperture of the medicine outlet is small, and the sealing plate 2 impacts the medicine liquid to atomize the medicine liquid. In the drug delivery device of the present invention, the piezoelectric ceramic sheet 3 directly drives the wind plate to vibrate. When the drug delivery device is not in use, the sealing plate 2 realizes the sealing of the medicine liquid. When the drug delivery device is in use, the sealing plate 2 realizes the effects of drug delivery and atomization, which greatly simplifies the structure of the drug delivery device, reduces the processing cost of the drug delivery device, and is conducive to promotion.

[0046] The above is only a preferred embodiment of the present invention. It should be pointed out that for ordinary technicians in this technical field, several improvements and substitutions can be made without departing from the technical principles of the present invention. These improvements and substitutions should also be regarded as the scope of protection of the present invention.

Claims

1. A drug delivery device, characterized in that: It comprises a drug delivery head (1), a sealing plate (2) and a piezoelectric ceramic sheet (3); The drug delivery head (1) comprises a drug-containing cavity (111) and a drug delivery channel (112), wherein the drug-containing cavity (111) is used to contain drug solution, and one end of the drug delivery channel (112) is connected to the drug-containing cavity (111), and the other end is connected to the outside; The sealing plate (2) is arranged in the drug delivery channel (112), and the sealing plate (2) has a plurality of drug outlet holes, and each of the drug outlet holes is configured to: prevent the drug solution from flowing out by surface tension when not vibrated; The piezoelectric ceramic sheet (3) is arranged in the drug delivery channel (112), and the piezoelectric ceramic sheet (3) connects the drug delivery head (1) and the sealing plate (2). The piezoelectric ceramic sheet (3) drives the sealing plate (2) to vibrate, so that the drug solution is impacted by the sealing plate (2) and flows out from the drug outlet.

2. The drug delivery device according to claim 1, characterized in that: The inner wall of the drug administration channel (112) is provided with an annular groove (113), the piezoelectric ceramic sheet (3) is an annular sheet with a through hole (31) in the middle, the sealing plate (2) and the piezoelectric ceramic sheet (3) are both arranged in the annular groove (113), and each of the drug outlet holes is arranged opposite to the through hole (31) in the axial direction of the drug administration channel (112).

3. The drug delivery device according to claim 2, characterized in that: The annular groove (113) comprises a first groove wall (1131) and a second groove wall (1132) which are arranged opposite to each other in the axial direction of the drug administration channel (112); the piezoelectric ceramic sheet (3) is a telescopically deformable piezoelectric ceramic sheet, one end of which is connected to the first groove wall (1131), and the other end of which is connected to the sealing plate (2); the sealing plate (2) and the second groove wall (1132) are arranged opposite to each other in the axial direction of the drug administration channel (112).

4. The drug delivery device according to claim 3, characterized in that: The drug delivery device further comprises a first elastic ring (41), wherein the first elastic ring (41) is arranged in the annular groove (113), and the first elastic ring (41) is located in the interval between the sealing plate (2) and the second groove wall (1132), and one end of the first elastic ring (41) abuts against the sealing plate (2), and the other end abuts against the second groove wall (1132).

5. The drug delivery device according to claim 2, characterized in that: The piezoelectric ceramic sheet (3) is a bending-deformed piezoelectric ceramic sheet, and the bending-deformed piezoelectric ceramic sheet is fitted and fixed to the sealing plate (2).

6. The drug delivery device according to claim 5, characterized in that: The annular groove (113) comprises a first groove wall (1131) and a second groove wall (1132) which are arranged axially opposite to each other in the drug delivery channel (112), and the drug delivery device further comprises a second elastic ring (42) and a third elastic ring (43) which are arranged in the annular groove (113); in the axial direction of the annular groove (113), the first groove wall (1131), the second elastic ring (42), the bending deformable piezoelectric ceramic sheet, the sealing plate (2), the third elastic ring (43) and the second groove wall (1132) are abutted in sequence.

7. The drug delivery device according to claim 1, characterized in that: The medicine outlet hole is a circular hole, and the diameter of the medicine outlet hole is greater than or equal to 0.2 microns and less than or equal to 200 microns.

8. The drug delivery device according to claim 1, characterized in that: The drug delivery device further comprises a sealing cover (5), wherein the sealing cover (5) is detachably connected to the drug delivery head (1), and the sealing cover (5) seals the drug delivery end of the drug delivery channel (112).

9. The drug delivery device according to claim 1, characterized in that: The drug delivery device further comprises a drug delivery device body (6), wherein a circuit board (61) is provided in the drug delivery device body (6), wherein the drug delivery device body (6) has a threaded hole (65), wherein a first conductive portion (64) electrically connected to the circuit board (61) is provided in the threaded hole (65); the drug delivery head (1) has a threaded joint, wherein the threaded joint has a second conductive portion (1221) electrically connected to the piezoelectric ceramic sheet (3), wherein the threaded joint is threadedly matched and arranged in the threaded hole (65) so that the first conductive portion (64) can abut against the second conductive portion (1221).

10. The drug delivery device according to claim 9, characterized in that: The drug delivery device further comprises a sealing ring (7), the drug delivery head (1) comprises a docking platform protruding toward the outside of the threaded joint, the sealing ring (7) is sleeved on the outside of the threaded joint, and two sides of the sealing ring (7) respectively abut against the docking platform and the outer peripheral edge of the threaded hole (65).

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