Solid material real-time detection and distribution device

By designing real-time detection and diversion devices for solid materials, the problem that traditional batch sampling inspections cannot meet the real-time detection requirements of continuous manufacturing of drugs is solved, and the continuous and real-time detection and diversion of materials are achieved, ensuring product quality stability and reducing pollution risks.

CN119972540APending Publication Date: 2025-05-13SHANGHAI HAN OU PHARMA EQUIP CO LTD
View PDF 0 Cites 0 Cited by

Patent Information

Application Number
CN202510332709.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-03-20
Publication Date
2025-05-13

AI Technical Summary

Technical Problem

Traditional batch sampling methods cannot meet the real-time inspection needs of continuous drug manufacturing, making it difficult to ensure product quality stability.

Method used

A real-time detection and diversion device for solid materials is designed, including a diversion main body, an online detection probe, a probe cleaning component and a waste removal component to realize real-time detection and diversion of materials.

Benefits of technology

It realizes continuous and real-time inspection and diversion of materials, ensures that the product quality meets requirements, has a simple structure, is easy to install and maintain, and is compatible with a variety of online inspection tools, reducing the contact between production personnel and materials, and reducing the risk of pollution.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN119972540A_ABST
    Figure CN119972540A_ABST
Patent Text Reader

Abstract

The invention discloses a solid material real-time detecting and distributing device which comprises a distributing body, a feeding opening, a qualified material outlet, a waste removing material outlet, an online detecting probe, a probe cleaning assembly and a waste removing assembly. The upper end of the flow dividing main body is connected with the feeding hole, the lower end of the flow dividing main body is connected with the qualified material outlet, and the waste removing material outlet is connected to the lower side wall of the flow dividing main body; the on-line detection probe is connected to the inner wall of the shunting main body, and the probe cleaning assembly is connected to the on-line detection probe; the inner wall of the flow dividing main body is connected with the waste removing assembly, the waste removing assembly is located at the waste removing discharging port, and the solid material real-time detecting and flow dividing device is provided for overcoming existing defects and meets the current continuous manufacturing requirement.
Need to check novelty before this filing date? Find Prior Art

Description

Technical Field

[0001] The invention relates to a real-time detection and diversion device for solid materials. Background Art

[0002] At present, the continuous manufacturing technology of pharmaceuticals is developing rapidly. It has many advantages, such as improving efficiency and stability, reducing costs and space, and enhancing flexibility.

[0003] Real-time material detection and diversion technology is a very important part, which determines the stability of the entire continuous production line. The traditional batch sampling method can no longer meet the needs of continuous manufacturing. There is an urgent need for a device that can detect product quality attributes and divert in real time. Therefore, a real-time detection and diversion device for solid materials is proposed to address the above problems. Summary of the invention

[0004] The purpose of the present invention is to overcome the existing defects and provide a real-time detection and diversion device for solid materials to meet the current needs of continuous manufacturing.

[0005] To achieve the above-mentioned object, the present invention provides the following technical solutions: a real-time detection and diversion device for solid materials, comprising a diversion body, a feed inlet, a qualified material outlet, a reject material outlet, an online detection probe, a probe cleaning component and a reject component;

[0006] The upper end of the diversion body is connected to the feed port, and the lower end is connected to the qualified discharge port, and the waste discharge port is connected to the lower side wall of the diversion body; the online detection probe is connected to the inner wall of the diversion body, and the probe cleaning assembly is connected to the online detection probe; the inner wall of the diversion body is connected to the waste rejection assembly, and the waste rejection assembly is located at the waste rejection discharge port.

[0007] Preferably, the probe cleaning assembly includes a first oscillating cylinder, the output end of the first oscillating cylinder is connected to a rotating shaft, the rotating shaft passes through the inner side of the diversion body and is connected to a brush mounting plate, a cleaning brush is connected to the brush mounting plate, and the cleaning brush contacts the online detection probe.

[0008] Preferably, the waste rejection component includes a second swing cylinder, the output end of the second swing cylinder penetrates to the inner side of the diversion body and is connected to a waste rejection valve plate, and the waste rejection valve plate covers the waste rejection outlet.

[0009] Preferably, the output end of the first oscillating cylinder is connected to a spring adjusting seat, the spring adjusting seat is connected to a spring mounting seat, a pre-tightening spring is internally connected to the spring mounting seat, and the pre-tightening spring is sleeved on the rotating shaft.

[0010] Preferably, an observation window is provided on the side wall of the diversion body.

[0011] Preferably, the first swing cylinder is connected to a cylinder mounting bracket.

[0012] Preferably, the online detection probe is electrically connected to a control device, and the control device is electrically connected to the first swing cylinder and the second swing cylinder.

[0013] Preferably, the second swing cylinder is connected to the side wall of the diverter body via a cylinder mounting flange.

[0014] Compared with the prior art, the beneficial effects of the present invention are as follows: the real-time detection and diversion device for solid materials can continuously and in real time detect the key quality attributes of the input materials, and divert them in real time according to the release standards to ensure that the products entering the downstream meet the requirements; the structure is simple and easy to install and maintain; the compatibility is strong and can be compatible with a variety of online detection tools, such as near-infrared spectroscopy technology, Raman spectroscopy technology, microwave online detection technology, etc. Fully automatic operation reduces the number of production personnel and their contact with materials, thereby reducing the risk of contamination. Rapid response and small diversion error; the path between the online detection probe and the rejection valve plate is short, and the diversion valve plate can respond immediately after the material is detected online to obtain information, ensuring the timeliness and accuracy of the real-time release detection of the material. BRIEF DESCRIPTION OF THE DRAWINGS

[0015] The accompanying drawings are used to provide a further understanding of the present invention and constitute a part of the specification. Together with the embodiments of the present invention, they are used to explain the present invention and do not constitute a limitation of the present invention. In the accompanying drawings:

[0016] Figure 1 It is a schematic diagram of the real-time detection and diversion device for solid materials of the present invention;

[0017] Figure 2 It is a side view of the real-time detection and diversion device for solid materials of the present invention;

[0018] Figure 3 It is a front view of the real-time detection and diversion device for solid materials of the present invention;

[0019] Figure 4 is an axonometric view of the probe cleaning assembly of the present invention;

[0020] Figure 5 is a cross-sectional view of the probe cleaning assembly of the present invention;

[0021] Figure 6 A schematic diagram of the motion of the probe cleaning assembly of the present invention;

[0022] Figure 7 It is a motion schematic diagram of the waste rejection component of the present invention.

[0023] In the figure: 1. diversion body; 2. feed inlet; 3. qualified discharge port; 4. reject discharge port; 5. online detection probe; 6. first swing cylinder; 7. rotating shaft; 8. brush mounting plate; 9. cleaning brush; 10. second swing cylinder; 11. reject valve plate; 12. spring adjustment seat; 13. spring mounting seat; 14. preload spring; 15. observation window; 16. cylinder mounting bracket; 17. cylinder mounting flange. DETAILED DESCRIPTION

[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the present invention.

[0025] See also Figure 1-7 A real-time detection and diversion device for solid materials, comprising a diversion body 1, a feed port 2, a qualified discharge port 3, a reject discharge port 4, an online detection probe 5, a probe cleaning component and a reject discharge port; the upper end of the diversion body 1 is connected to the feed port 2, the lower end is connected to the qualified discharge port 3, and the reject discharge port 4 is connected to the lower side wall of the diversion body 1; the online detection probe 5 is connected to the inner wall of the diversion body 1, and the online detection probe 5 is connected to the probe cleaning component; the inner wall of the diversion body 1 is connected to the reject discharge port 4. The real-time detection and diversion device for solid materials is in the form of a single input and double output, and the three interfaces are all clamp-type flat joints for easy disassembly and assembly; the main material channel and the installation surface of the diversion device form an angle of 60° to ensure smooth material transportation.

[0026] See also Figure 4 , 5 6, the probe cleaning assembly includes a first swing cylinder 6, the output end of the first swing cylinder 6 is connected to the rotating shaft 7, the rotating shaft 7 penetrates the inner side of the diversion body 1, and is connected to the brush mounting plate 8, the brush mounting plate 8 is connected to the cleaning brush 9, and the cleaning brush 9 contacts the online detection probe 5. The first swing cylinder 6 is connected to the cylinder mounting bracket 16. The first swing cylinder 6 rotates to drive the cleaning brush 9 to swing, and clean the residual materials of the online detection probe 5.

[0027] Specifically, the output end of the first swing cylinder 6 is connected to a spring adjustment seat 12, and the spring adjustment seat 12 is connected to a spring mounting seat 13. The spring mounting seat 13 is internally connected to a preload spring 14, and the preload spring 14 is sleeved on the rotating shaft 7. The size of the preload force is changed by adjusting the position of the spring adjustment seat 12 to achieve a suitable cleaning effect. The online detection probe 5 is installed on the bottom surface of the main logistics channel, and a probe cleaning assembly is arranged on the upper side. The probe cleaning assembly adopts a preload design. The cleaning brush 9 is connected to the preload spring 14 through the brush mounting plate 8 and the rotating shaft 7. The size of the preload force is changed by adjusting the position of the spring adjustment seat to achieve a suitable cleaning effect. The probe cleaning assembly can regularly clean the material on the probe surface to prevent local materials from staying on the probe surface for a long time due to electrostatic adsorption or other reasons, affecting the detection data.

[0028] Specifically, the online detection probe 5 can use online near-infrared spectroscopy technology and Raman spectroscopy technology to detect key quality attributes of materials in real time, such as content, moisture, mixing uniformity, etc.

[0029] Specifically, the waste rejection assembly includes a second swing cylinder 10, the output end of which penetrates the inner side of the diverter body 1 and is connected to a waste rejection valve plate 11, which covers the waste rejection outlet 4. The second swing cylinder 10 is connected to the side wall of the diverter body 1 through a cylinder mounting flange 17.

[0030] Specifically, under normal circumstances, the waste rejection valve plate 11 is against the inner wall of the diverter body 1. When it is found that the material has problems and needs to be rejected, the second swing cylinder 10 drives the waste rejection valve plate 11 to rotate, so that the waste rejection valve plate 11 flips 90 degrees, blocks the channel of the diverter body 1, and allows the problematic material to be discharged from the waste rejection outlet 4.

[0031] Specifically, a waste rejection valve plate 11 is arranged below the online detection probe 5, and the key quality attribute information of the material detected online is transmitted to the control system to judge in real time whether the material is qualified. If the material is qualified, the diverter valve plate is closed, and the material flows to the qualified discharge port; if the material is unqualified, the diverter valve plate is opened, and the material flows to the waste rejection discharge port.

[0032] Specifically, the online detection probe 5 is electrically connected to the control device, and the control device is electrically connected to the first swing cylinder 6 and the second swing cylinder 10. When the online detection probe 5 detects that the material is unsuitable, it sends a signal to the control device to control the second swing cylinder 10 to move and block the channel of the diversion body 1, so that the problematic material is discharged from the waste discharge port 4. The control device can also control the first swing cylinder 6 to move to clean the online detection probe 5.

[0033] Specifically, an observation window 15 is provided on the side wall of the diverter body 1 to facilitate observation of the material conditions.

[0034] This real-time detection and diversion device for solid materials can continuously and in real time detect the key quality attributes of input materials, and divert them in real time according to the release standards to ensure that the products entering the downstream meet the requirements; it has a simple structure and is easy to install and maintain; it has strong compatibility and can be compatible with a variety of online detection tools, such as near-infrared spectroscopy technology, Raman spectroscopy technology, microwave online detection technology, etc. Fully automatic operation reduces the number of production personnel and their contact with materials, thereby reducing the risk of contamination. Quick response and small diversion error; the path between the online detection probe and the rejection valve plate is short, and the diversion valve plate can respond immediately after the material is detected online to obtain information, ensuring the timeliness and accuracy of the real-time release detection of the material.

[0035] Finally, it should be noted that the above are only preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art can still modify the technical solutions described in the aforementioned embodiments or replace some of the technical features therein by equivalents. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A solid material real-time detection and diversion device, characterized in that: It comprises a flow diversion body (1), a material inlet (2), a qualified material outlet (3), a waste material outlet (4), an online detection probe (5), a probe cleaning component and a waste material outlet; The upper end of the diverter body (1) is connected to the feed port (2), the lower end is connected to the qualified discharge port (3), and the reject discharge port (4) is connected to the lower side wall of the diverter body (1); the online detection probe (5) is connected to the inner wall of the diverter body (1), and the probe cleaning component is connected to the online detection probe (5); the inner wall of the diverter body (1) is connected to the reject component, and the reject component is located at the reject discharge port (4).

2. The solid material real-time detection and diversion device according to claim 1, characterized in that: The probe cleaning assembly comprises a first oscillating cylinder (6), the output end of the first oscillating cylinder (6) is connected to a rotating shaft (7), the rotating shaft (7) penetrates the inner side of the diversion body (1) and is connected to a brush mounting plate (8), a cleaning brush (9) is connected to the brush mounting plate (8), and the cleaning brush (9) contacts the online detection probe (5).

3. The solid material real-time detection and diversion device according to claim 1, characterized in that: The waste rejection assembly comprises a second swing cylinder (10), the output end of the second swing cylinder (10) penetrates the inner side of the diversion body (1) and is connected to a waste rejection valve plate (11), and the waste rejection valve plate (11) covers the waste rejection outlet (4).

4. The solid material real-time detection and diversion device according to claim 2, characterized in that: The output end of the first swing cylinder (6) is connected to a spring adjustment seat (12), the spring adjustment seat (12) is connected to a spring mounting seat (13), the spring mounting seat (13) is internally connected to a preload spring (14), and the preload spring (14) is sleeved on the rotating shaft (7).

5. The solid material real-time detection and diversion device according to claim 1, characterized in that: An observation window (15) is provided on the side wall of the diverter body (1).

6. The solid material real-time detection and diversion device according to claim 2, characterized in that: The first swing cylinder (6) is connected to a cylinder mounting bracket (16).

7. The solid material real-time detection and diversion device according to claim 2, characterized in that: The online detection probe (5) is electrically connected to a control device, and the control device is electrically connected to the first swing cylinder (6) and the second swing cylinder (10).

8. The solid material real-time detection and diversion device according to claim 3, characterized in that: The second swing cylinder (10) is connected to the side wall of the flow diverter body (1) via a cylinder mounting flange (17).