Antibacterial epoxy resin coating and preparation method thereof

Abstract

The invention discloses an antibacterial epoxy resin coating and a preparation method thereof, and relates to the technical field of coatings. According to the invention, the 5-phenylpent-2, 4-dienoic acid is esterified and combined with the side chain of the epoxy resin, so that the hardness and heat resistance of the cured coating are improved; then addition reaction with dimethyl diallyl ammonium chloride, 2-acrylamide phenylboronic acid and the modified antibacterial agent is performed to form a three-dimensional network structure, so that the mechanical strength of the coating is remarkably enhanced, the antibacterial, high-adhesion and anti-stripping effects are achieved, a phenylboronic acid structure is assisted, a protective film is formed on the surface of an object, the object is effectively isolated from the external environment, and the service life of the coating is prolonged. Oxidation and corrosion of the object surface are prevented, and the corrosion-resistant effect is achieved. According to the modified antibacterial agent, S-adenosine-L-homocysteine and silver nitrate are subjected to a coordination reaction, and the antibacterial effect is achieved; then, the silicon dioxide is combined with vinyl trichlorosilane, silane groups are introduced, after curing, the mechanical strength and water resistance of the coating are remarkably enhanced, corrosive liquid is prevented from entering the coating, and the corrosion-resistant effect is indirectly improved.

Description

Technical Field

[0001] The invention relates to the technical field of coatings, in particular to an antibacterial epoxy resin coating and a preparation method thereof. Background Art

[0002] Epoxy resins are widely used in the fields of bonding various metals and non-metallic materials, corrosion-resistant coatings, electrical insulation materials, composite materials, etc. due to their excellent adhesion, corrosion resistance, stability, insulation and mechanical strength. Most commonly used epoxy resins are viscous liquids or solids, insoluble in water, and only soluble in organic solvents. Most organic solvents are volatile, toxic, flammable and explosive, so the application of epoxy resins is subject to certain restrictions. Epoxy resins with water as the dispersion medium are not only environmentally friendly, but also can reduce the cost of epoxy resins. Therefore, the research on water-based epoxy resins has received more and more attention.

[0003] However, my country started research on waterborne epoxy resins relatively late, and the main research and development was on two-component waterborne epoxy resin systems, which need to be used in conjunction with a curing agent. The resulting products have disadvantages such as inconvenient construction, energy consumption for heating and curing, and inconvenient storage. At the same time, the functions of the self-cross-linking waterborne epoxy resin coatings currently developed and published are relatively simple and cannot meet the use requirements under specific conditions. Summary of the invention

[0004] The object of the present invention is to provide an antibacterial epoxy resin coating and a preparation method thereof, so as to solve the problems existing in the prior art.

[0005] In order to solve the above technical problems, the present invention provides the following technical solutions: an antibacterial epoxy resin coating, which mainly includes 44 to 56 parts of water-based self-crosslinking modified epoxy resin, 0.2 to 0.4 parts of defoaming agent, 0.5 to 0.9 parts of leveling agent, 2 to 6 parts of filler, 0.3 to 0.5 parts of NX-8502 curing agent, 58 to 74 parts of deionized water, and 30 to 40 parts of ethanol by weight.

[0006] Furthermore, the water-based self-crosslinking modified epoxy resin is prepared from 5-phenylpenta-2,4-dienoic acid, epoxy resin, dimethyldiallylammonium chloride, 2-acrylamidephenylboric acid, and a modified antibacterial agent.

[0007] Furthermore, the modified antibacterial agent is prepared from S-adenosyl-L-homocysteine, silver nitrate and chloropropyltrichlorosilane.

[0008] Furthermore, a method for preparing an antibacterial epoxy resin coating comprises the following preparation steps:

[0009] (1) Under a nitrogen atmosphere, 15 to 25 parts of epoxy resin are dissolved in 50 to 80 parts of toluene, and after being stirred evenly, 10 to 16 parts of 5-phenylpenta-2,4-dienoic acid are added, the temperature is raised to 80 to 90° C., 2 to 4 parts of a 10 wt% toluene solution of dibutyltin dilaurate are added dropwise, the temperature is continued to be raised to 100 to 110° C., and the mixture is stirred at 80 rpm for 2 to 4 hours, and concentrated at a vacuum degree of -0.08 MPa and 40° C. for 1 to 3 hours to obtain an esterified epoxy resin;

[0010] (2) Under a nitrogen atmosphere, 10 to 20 parts of esterified epoxy resin and 50 to 100 parts of ethylene glycol butyl ether were mixed uniformly, the temperature was raised to 90 to 100° C., 2 to 4 parts of the mixed reaction solution were added dropwise at a rate of 0.5 drops / s, and the mixture was stirred at 100 rpm for 5 to 7 hours. 5 to 15 parts of N, N-dimethylethanolamine were added and the stirring was continued for 20 to 40 minutes. Subsequently, 10 to 30 parts of deionized water were added and the mixture was emulsified at 1000 rpm for 30 to 50 minutes to obtain a water-based self-crosslinking modified epoxy resin;

[0011] (3) 44-56 parts of water-based self-crosslinking modified epoxy resin, 0.2-0.4 parts of defoaming agent, 0.5-0.9 parts of leveling agent, 2-6 parts of filler, 0.3-0.5 parts of NX-8502 curing agent, 58-74 parts of deionized water, and 30-40 parts of ethanol are mixed uniformly to prepare an antibacterial epoxy resin coating.

[0012] Furthermore, the epoxy resin model in step (1) is any one of BFE-170, NPEF-170, and DER-354.

[0013] Furthermore, the preparation step of the mixed reaction liquid in step (2) is: 3 to 4 parts of dimethyldiallylammonium chloride, 4 to 6 parts of 2-acrylamidephenylboric acid, 5 to 7 parts of modified antibacterial agent, and 40 to 60 parts of ethylene glycol butyl ether are mixed uniformly to obtain a mixed reaction liquid.

[0014] Furthermore, the preparation steps of the modified antibacterial agent are as follows: dissolving 2 to 8 parts of silver nitrate and 5 to 15 parts of S-adenosyl-L-homocysteine ​​in 98 to 296 parts of deionized water, adjusting the pH to 6 to 7 with a 0.5 mol / L sodium hydroxide aqueous solution, heating to 70 to 90°C, stirring at 120 rpm for 1 to 2 hours, filtering the filtrate, standing at 20 to 30°C for 36 to 60 hours, filtering the solid, drying it in an oven at 50 to 60°C for 4 to 8 hours, adding 45 to 65 parts of dichloromethane and stirring evenly, cooling to -5 to 5°C, then adding 9 to 18 parts of vinyltrichlorosilane and 10 to 20 parts of triethylamine, reacting for 8 to 16 hours at 100 rpm, filtering the solid, washing it 3 times with dichloromethane, and drying it in an oven at 25 to 35°C for 4 to 8 hours to obtain the modified antibacterial agent.

[0015] Furthermore, the defoaming agent in step (3) is any one of SPE-810, SPE-1000, and VES-100.

[0016] Furthermore, the leveling agent in step (3) is any one of BYK-354, BYK-310, and Tech-100.

[0017] Furthermore, the filler in step (3) is a mixture of one or more of silicon dioxide, kaolin, calcium carbonate, barium sulfate, aluminum hydroxide, and carbon nanotubes.

[0018] Compared with the prior art, the beneficial effects achieved by the present invention are:

[0019] The present invention first utilizes the carboxyl group in 5-phenylpenta-2,4-dienoic acid to esterify and combine with the hydroxyl group in the side chain of the epoxy resin, introduces multiple unsaturated double bonds, provides binding sites for subsequent reactions, and simultaneously introduces phenyl groups, which has a high steric hindrance effect, reduces the distance between the epoxy resin molecular chains, thereby increasing the intermolecular force, thereby increasing the hardness of the coating after curing, and also improving the heat resistance of the coating; then, it reacts with the unsaturated double bonds in dimethyldiallylammonium chloride, 2-acrylamidephenylboronic acid, and the modified antibacterial agent to form a three-dimensional network structure, which significantly enhances the coating. Mechanical strength; the cations contained in dimethyldiallylammonium chloride can destroy bacterial growth and achieve antibacterial effect, and can form a strong connection with the surface of the object, thereby achieving high adhesion and anti-peeling effects. On this basis, the amide group contained in 2-acrylamidephenylboronic acid has good hydrophilicity and is easy for other functional groups to form hydrogen bonds, thereby improving the durability of the coating and assisting the phenylboronic acid structure to form a dense protective film on the surface of the object, effectively isolating the object from the external environment, preventing oxidation and corrosion on the surface of the object, and achieving corrosion resistance.

[0020] Among them, the modified antibacterial agent is made of S-adenosyl-L-homocysteine, silver nitrate and chloropropyltrichlorosilane; the carboxyl group in S-adenosyl-L-homocysteine ​​is used to coordinate with silver nitrate to form a network structure with silver as the central ion, thereby achieving a slow controlled release of silver ions, significantly improving the overall thermal stability and antibacterial properties, and introducing sulfur elements, which can react with enzymes in bacteria, destroy the cell walls of bacteria, and make the bacteria lose their ability to survive, thereby achieving an antibacterial effect; and then introducing silane groups through the combination of amino groups and the chlorine groups of vinyltrichlorosilane, which significantly enhances the mechanical strength and water resistance of the coating after curing, isolates corrosive liquids from entering the coating, and indirectly improves the corrosion resistance. DETAILED DESCRIPTION

[0021] The following will be combined with the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the described embodiments are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative work are within the scope of protection of the present invention.

[0022] In order to more clearly illustrate the method provided by the present invention, the following examples are used to describe in detail the various index testing methods of the antibacterial epoxy resin coatings prepared in the following examples are as follows:

[0023] Impact strength: Take the same mass of the embodiment and the comparative example, apply them on a tinplate of 155 mm × 70 mm × 0.2 mm, cure them at 60 ° C for 8 h, and test their impact strength according to GB / T1732-2020 after cooling.

[0024] Salt spray resistance: Take the same mass of the embodiment and the comparative example, apply them on a tinplate of 155mm×70mm×0.2mm, cure at 60°C for 8h, and test the salt spray resistance according to GB / T1771-2007 after cooling.

[0025] Adhesion: Take the same mass of the embodiment and the comparative example, apply them on a tinplate of 155mm×70mm×0.2mm, cure at 60°C for 8h, adhere with adhesive tape after cooling and then tear it off to observe the peeling of the coating.

[0026] Antibacterial rate: Take the same mass of the embodiment and the comparative example, and test the antibacterial rate of the coating according to GB / T 21866-2008.

[0027] Example 1

[0028] (1) Under a nitrogen atmosphere, 15 parts of BFE-170 epoxy resin were dissolved in 50 parts of toluene, and after being stirred evenly, 10 parts of 5-phenylpenta-2,4-dienoic acid were added, the temperature was raised to 80° C., 2 parts of 10 wt% dibutyltin dilaurate toluene solution were added dropwise, the temperature was continued to be raised to 100° C., and the mixture was stirred at 80 rpm for 2 h, and concentrated at a vacuum degree of -0.08 MPa and 40° C. for 1 h to obtain an esterified epoxy resin;

[0029] (2) Dissolve 2 parts of silver nitrate and 5 parts of S-adenosyl-L-homocysteine ​​in 98 parts of deionized water, adjust the pH to 6 with 0.5 mol / L sodium hydroxide aqueous solution, heat to 70°C, stir at 120 rpm for 1 hour, filter the filtrate, let stand at 20°C for 36 hours, filter the solid, dry in an oven at 50°C for 4 hours, add 45 parts of dichloromethane and stir evenly, cool to -5°C, then add 9 parts of vinyltrichlorosilane and 10 parts of triethylamine, react at 100 rpm for 8 hours, filter the solid, wash with dichloromethane 3 times, and dry in an oven at 25°C for 4 hours to obtain a modified antibacterial agent;

[0030] (3) mixing 3 parts of dimethyldiallylammonium chloride, 4 parts of 2-acrylamidephenylboric acid, 5 parts of modified antibacterial agent, and 40 parts of ethylene glycol butyl ether to obtain a mixed reaction liquid;

[0031] (4) Under a nitrogen atmosphere, 10 parts of esterified epoxy resin and 50 parts of ethylene glycol butyl ether were mixed uniformly, the temperature was raised to 90° C., 2 parts of the mixed reaction solution were added dropwise at a rate of 0.5 drops / s, and the mixture was stirred at 100 rpm for 5 h. 5 parts of N,N-dimethylethanolamine were added and the stirring was continued for 20 min. Subsequently, 10 parts of deionized water were added and the mixture was emulsified at 1000 rpm for 30 min to obtain a water-based self-crosslinking modified epoxy resin;

[0032] (5) 44 parts of water-based self-crosslinking modified epoxy resin, 0.2 parts of SPE-810 defoaming agent, 0.5 parts of BYK-354 leveling agent, 2 parts of kaolin, 0.3 parts of NX-8502 curing agent, 58 parts of deionized water, and 30 parts of ethanol were mixed uniformly to prepare an antibacterial epoxy resin coating.

[0033] Example 2

[0034] (1) Under a nitrogen atmosphere, 20 parts of NPEF-170 epoxy resin were dissolved in 65 parts of toluene, and 13 parts of 5-phenylpenta-2,4-dienoic acid were added after stirring evenly, and the temperature was raised to 85° C., and 3 parts of 10 wt% dibutyltin dilaurate toluene solution were added dropwise, and the temperature was continued to rise to 105° C., and the mixture was stirred at 80 rpm for 3 h, and concentrated at a vacuum degree of -0.08 MPa and 40° C. for 2 h to obtain an esterified epoxy resin;

[0035] (2) Dissolve 5 parts of silver nitrate and 10 parts of S-adenosyl-L-homocysteine ​​in 197 parts of deionized water, adjust the pH to 6.5 with 0.5 mol / L sodium hydroxide aqueous solution, heat to 80°C, stir at 120 rpm for 1.5 hours, filter the filtrate, let stand at 25°C for 48 hours, filter the solid, dry it in an oven at 55°C for 6 hours, add 55 parts of dichloromethane and stir evenly, cool to 0°C, then add 13.5 parts of vinyltrichlorosilane and 15 parts of triethylamine, react at 100 rpm for 12 hours, filter the solid, wash it 3 times with dichloromethane, and dry it in an oven at 30°C for 6 hours to obtain a modified antibacterial agent;

[0036] (3) 3.5 parts of dimethyldiallylammonium chloride, 5 parts of 2-acrylamidephenylboric acid, 6 parts of modified antibacterial agent, and 50 parts of ethylene glycol butyl ether were mixed uniformly to prepare a mixed reaction liquid;

[0037] (4) Under a nitrogen atmosphere, 15 parts of esterified epoxy resin and 75 parts of ethylene glycol butyl ether were mixed uniformly, the temperature was raised to 95° C., 3 parts of the mixed reaction solution were added dropwise at a rate of 0.5 drops / s, and the mixture was stirred at 100 rpm for 6 h. 10 parts of N,N-dimethylethanolamine were added and continued to stir for 30 min. Subsequently, 20 parts of deionized water were added and high-speed emulsified at 1000 rpm for 40 min to obtain a water-based self-crosslinking modified epoxy resin;

[0038] (5) 50 parts of water-based self-crosslinking modified epoxy resin, 0.3 parts of SPE-1000 defoaming agent, 0.7 parts of BYK-310 leveling agent, 4 parts of calcium carbonate, 0.4 parts of NX-8502 curing agent, 66 parts of deionized water, and 35 parts of ethanol were mixed uniformly to prepare an antibacterial epoxy resin coating.

[0039] Example 3

[0040] (1) Under a nitrogen atmosphere, 25 parts of DER-354 epoxy resin were dissolved in 80 parts of toluene, and 16 parts of 5-phenylpenta-2,4-dienoic acid were added after stirring evenly. The temperature was raised to 90° C., and 4 parts of 10 wt% dibutyltin dilaurate toluene solution were added dropwise. The temperature was continued to rise to 110° C., and the mixture was stirred at 80 rpm for 4 h. The mixture was concentrated at a vacuum degree of -0.08 MPa and 40° C. for 3 h to obtain an esterified epoxy resin.

[0041] (2) 8 parts of silver nitrate and 15 parts of S-adenosyl-L-homocysteine ​​were dissolved in 296 parts of deionized water, and the pH was adjusted to 7 with a 0.5 mol / L sodium hydroxide aqueous solution, the temperature was raised to 90°C, and the mixture was stirred at 120 rpm for 2 h. The filtrate was filtered and allowed to stand at 30°C for 60 h. The solid was filtered and dried in an oven at 60°C for 8 h. 65 parts of dichloromethane were added and stirred evenly. The mixture was cooled to 5°C, and then 18 parts of vinyltrichlorosilane and 20 parts of triethylamine were added. The mixture was stirred at 100 rpm for 16 h. The solid was filtered and washed three times with dichloromethane. The mixture was dried in an oven at 35°C for 8 h to obtain a modified antibacterial agent.

[0042] (3) 4 parts of dimethyldiallylammonium chloride, 6 parts of 2-acrylamidephenylboric acid, 7 parts of modified antibacterial agent, and 60 parts of ethylene glycol butyl ether were mixed uniformly to prepare a mixed reaction liquid;

[0043] (4) Under a nitrogen atmosphere, 20 parts of esterified epoxy resin and 100 parts of ethylene glycol butyl ether were mixed uniformly, the temperature was raised to 100° C., 4 parts of the mixed reaction solution were added dropwise at a rate of 0.5 drops / s, and the mixture was stirred at 100 rpm for 7 h. 15 parts of N,N-dimethylethanolamine were added and stirred for 40 min. Subsequently, 30 parts of deionized water were added and high-speed emulsification was performed at 1000 rpm for 50 min to obtain a water-based self-crosslinking modified epoxy resin;

[0044] (5) 56 parts of water-based self-crosslinking modified epoxy resin, 0.4 parts of VES-100 defoaming agent, 0.9 parts of Tech-100 leveling agent, 6 parts of carbon nanotubes, 0.5 parts of NX-8502 curing agent, 74 parts of deionized water, and 40 parts of ethanol were mixed uniformly to prepare an antibacterial epoxy resin coating.

[0045] Comparative Example 1

[0046] The difference between Comparative Example 1 and Example 2 is that there is no step (1), and step (4) is changed to: in a nitrogen atmosphere, 15 parts of NPEF-170 epoxy resin and 75 parts of ethylene glycol butyl ether are mixed uniformly, the temperature is raised to 95° C., 3 parts of the mixed reaction solution are added dropwise at a rate of 0.5 drops / s, and the mixture is stirred at 100 rpm for 6 hours, 10 parts of N, N-dimethylethanolamine are added, and stirring is continued for 30 minutes, and then 20 parts of deionized water are added and high-speed emulsification is carried out at 1000 rpm for 40 minutes to obtain a water-based self-crosslinking modified epoxy resin. The remaining steps are the same as those in Example 2.

[0047] Comparative Example 2

[0048] The difference between Comparative Example 2 and Example 2 is that step (2) is different. Step (2) is changed to: 10 parts of S-adenosyl-L-homocysteine ​​and 55 parts of dichloromethane are stirred evenly, cooled to 0°C, and then 13.5 parts of vinyltrichlorosilane and 15 parts of triethylamine are added, and the mixture is stirred at 100 rpm for 12 hours, and the solid is filtered, washed with dichloromethane 3 times, and dried in an oven at 30°C for 6 hours to obtain a modified antibacterial agent. The remaining steps are the same as those in Example 2.

[0049] Comparative Example 3

[0050] The difference between Comparative Example 3 and Example 2 is that step (2) is different. Step (2) is changed to: 5 parts of silver nitrate are dispersed in 55 parts of dichloromethane, cooled to 0°C, then 13.5 parts of vinyltrichlorosilane and 15 parts of triethylamine are added, and the mixture is stirred at 100 rpm for 12 hours, and the solid is filtered, washed with dichloromethane 3 times, and dried in an oven at 30°C for 6 hours to obtain a modified antibacterial agent. The remaining steps are the same as those in Example 2.

[0051] Comparative Example 4

[0052] The difference between Comparative Example 4 and Example 2 is that step (2) is different. Step (2) is changed to: 5 parts of silver nitrate and 10 parts of S-adenosyl-L-homocysteine ​​are dissolved in 197 parts of deionized water, the pH is adjusted to 6.5 with 0.5 mol / L sodium hydroxide aqueous solution, the temperature is raised to 80°C, stirred at 120 rpm for 1.5 hours, the filtrate is filtered, and the mixture is allowed to stand at 25°C for 48 hours. The solid is filtered and dried in an oven at 55°C for 6 hours to obtain a modified antibacterial agent. The remaining steps are the same as those in Example 2.

[0053] Comparative Example 5

[0054] The difference between Comparative Example 5 and Example 2 is that step (3) is different, and step (3) is changed to: 5 parts of 2-acrylamide phenylboronic acid, 6 parts of modified antibacterial agent, and 50 parts of ethylene glycol butyl ether are mixed uniformly to obtain a mixed reaction liquid. The remaining steps are the same as those of Example 2.

[0055] Comparative Example 6

[0056] The difference between Comparative Example 6 and Example 2 is that step (3) is different, and step (3) is changed to: 3.5 parts of dimethyldiallyl ammonium chloride, 6 parts of modified antibacterial agent, and 50 parts of ethylene glycol butyl ether are mixed uniformly to obtain a mixed reaction liquid. The remaining steps are the same as those of Example 2.

[0057] Effect example

[0058] Table 1 below shows the performance analysis results of the antibacterial epoxy resin coatings of Examples 1 to 3 of the present invention and Comparative Examples 1 to 6.

[0059] Table 1

[0060]

[0061] From the comparison of the experimental data of Examples 1, 2, and 3 with those of Comparative Example 1, it can be found that the carboxyl group in 5-phenylpenta-2,4-dienoic acid is esterified with the hydroxyl group in the side chain of the epoxy resin to introduce multiple unsaturated double bonds, provide binding sites for subsequent reactions, and introduce phenyl groups at the same time, which has a high steric hindrance effect, reduces the distance between the epoxy resin molecular chains, increases the intermolecular force, improves the hardness of the coating after curing, and improves the heat resistance of the coating; from the comparison of the experimental data of Examples 1, 2, and 3 with those of Comparative Example 2, it can be found that the coordination reaction using silver nitrate can achieve the effect of slow controlled release of silver ions and play an antibacterial role; from the comparison of the experimental data of Examples 1, 2, and 3 with those of Comparative Example 3, it can be found that the use of S-adenosyl-L-homocysteine ​​to form a network structure with silver as the central ion can achieve the effect of slow controlled release of silver ions, significantly improve the overall thermal stability and antibacterial properties, and introduce sulfur elements, which can react with enzymes in bacteria to destroy the cell walls of bacteria and make the bacteria lose their The survivability of the coating is improved to achieve the antibacterial effect; from the comparison of the experimental data of Examples 1, 2, and 3 with Comparative Example 4, it can be found that by combining with vinyltrichlorosilane and introducing silane groups, the mechanical strength and water resistance of the coating are significantly enhanced after curing, and the corrosive liquid is isolated from entering the coating, thereby indirectly improving the corrosion resistance effect; from the comparison of the experimental data of Examples 1, 2, and 3 with Comparative Example 5, it can be found that the cations contained in dimethyldiallylammonium chloride can destroy the growth of bacteria to achieve the antibacterial effect, and can form a firm connection with the surface of the object, thereby achieving the effect of high adhesion and anti-stripping; from the comparison of the experimental data of Examples 1, 2, and 3 with Comparative Example 6, it can be found that the amide group contained in 2-acrylamidephenylboronic acid has good hydrophilicity, is easy to form hydrogen bonds with other functional groups, improves the durability of the coating, and assists the phenylboronic acid structure, and can form a dense protective film on the surface of the object, effectively isolating the contact between the object and the external environment, preventing oxidation and corrosion of the surface of the object, and achieving the corrosion resistance effect.

[0062] It will be apparent to those skilled in the art that the invention is not limited to the details of the exemplary embodiments described above and that the invention can be implemented in other specific forms without departing from the spirit or essential features of the invention. Therefore, the embodiments should be considered in all respects as exemplary and non-limiting, and the scope of the invention is defined by the appended claims rather than the foregoing description, and it is intended that all variations within the meaning and scope of the equivalent elements of the claims be included in the invention. Any marking in a claim should not be considered as limiting the claim to which it relates.

Claims

1. An antibacterial epoxy resin coating, characterized in that: The antibacterial epoxy resin coating mainly comprises, by weight, 44 to 56 parts of water-based self-crosslinking modified epoxy resin, 0.2 to 0.4 parts of defoaming agent, 0.5 to 0.9 parts of leveling agent, 2 to 6 parts of filler, 0.3 to 0.5 parts of NX-8502 curing agent, 58 to 74 parts of deionized water, and 30 to 40 parts of ethanol.

2. An antibacterial epoxy resin coating according to claim 1, characterized in that: The water-based self-crosslinking modified epoxy resin is prepared from 5-phenylpenta-2,4-dienoic acid, epoxy resin, dimethyldiallylammonium chloride, 2-acrylamidephenylboric acid and a modified antibacterial agent.

3. An antibacterial epoxy resin coating according to claim 2, characterized in that: The modified antibacterial agent is prepared from S-adenosyl-L-homocysteine, silver nitrate and chloropropyltrichlorosilane.

4. A method for preparing an antibacterial epoxy resin coating, characterized in that: The method comprises the following preparation steps: (1) Under a nitrogen atmosphere, 15 to 25 parts of epoxy resin are dissolved in 50 to 80 parts of toluene, and after being stirred evenly, 10 to 16 parts of 5-phenylpenta-2,4-dienoic acid are added, the temperature is raised to 80 to 90° C., 2 to 4 parts of a 10 wt% toluene solution of dibutyltin dilaurate are added dropwise, the temperature is continued to be raised to 100 to 110° C., and the mixture is stirred at 80 rpm for 2 to 4 hours, and concentrated at a vacuum degree of -0.08 MPa and 40° C. for 1 to 3 hours to obtain an esterified epoxy resin; (2) Under a nitrogen atmosphere, 10 to 20 parts of esterified epoxy resin and 50 to 100 parts of ethylene glycol butyl ether were mixed uniformly, the temperature was raised to 90 to 100° C., 2 to 4 parts of the mixed reaction solution were added dropwise at a rate of 0.5 drops / s, and the mixture was stirred at 100 rpm for 5 to 7 hours. 5 to 15 parts of N, N-dimethylethanolamine were added and the stirring was continued for 20 to 40 minutes. Subsequently, 10 to 30 parts of deionized water were added and the mixture was emulsified at 1000 rpm for 30 to 50 minutes to obtain a water-based self-crosslinking modified epoxy resin; (3) 44-56 parts of water-based self-crosslinking modified epoxy resin, 0.2-0.4 parts of defoaming agent, 0.5-0.9 parts of leveling agent, 2-6 parts of filler, 0.3-0.5 parts of NX-8502 curing agent, 58-74 parts of deionized water, and 30-40 parts of ethanol are mixed uniformly to prepare an antibacterial epoxy resin coating.

5. The method for preparing an antibacterial epoxy resin coating according to claim 4, characterized in that: The epoxy resin model in step (1) is any one of BFE-170, NPEF-170, and DER-354.

6. The method for preparing an antibacterial epoxy resin coating according to claim 4, characterized in that: The preparation step of the mixed reaction liquid in step (2) is as follows: 3 to 4 parts of dimethyldiallylammonium chloride, 4 to 6 parts of 2-acrylamidephenylboric acid, 5 to 7 parts of modified antibacterial agent, and 40 to 60 parts of ethylene glycol butyl ether are mixed uniformly to obtain a mixed reaction liquid.

7. The method for preparing an antibacterial epoxy resin coating according to claim 6, characterized in that: The preparation steps of the modified antibacterial agent are as follows: dissolving 2 to 8 parts of silver nitrate and 5 to 15 parts of S-adenosyl-L-homocysteine ​​in 98 to 296 parts of deionized water, adjusting the pH to 6 to 7 with a 0.5 mol / L sodium hydroxide aqueous solution, heating to 70 to 90° C., stirring at 120 rpm for 1 to 2 hours, filtering the filtrate, standing at 20 to 30° C. for 36 to 60 hours, filtering the solid, drying it in an oven at 50 to 60° C. for 4 to 8 hours, adding 45 to 65 parts of dichloromethane and stirring evenly, cooling to -5 to 5° C., then adding 9 to 18 parts of vinyltrichlorosilane and 10 to 20 parts of triethylamine, reacting for 8 to 16 hours with stirring at 100 rpm, filtering the solid, washing it with dichloromethane for 3 times, and drying it in an oven at 25 to 35° C. for 4 to 8 hours to obtain the modified antibacterial agent.

8. The method for preparing an antibacterial epoxy resin coating according to claim 4, characterized in that: The defoaming agent in step (3) is any one of SPE-810, SPE-1000 and VES-100.

9. The method for preparing an antibacterial epoxy resin coating according to claim 4, characterized in that: The leveling agent in step (3) is any one of BYK-354, BYK-310, and Tech-100.

10. The method for preparing an antibacterial epoxy resin coating according to claim 4, characterized in that: The filler in step (3) is a mixture of one or more of silicon dioxide, kaolin, calcium carbonate, barium sulfate, aluminum hydroxide, and carbon nanotubes.

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