Antibody detection equipment

Abstract

The invention discloses antibody detection equipment, and relates to the technical field of antibody detection, the antibody detection equipment comprises a box body, a feeding cavity, a detection cavity and a discharging cavity are sequentially formed in the box body, the box body is provided with carrying frames in the detection cavity, the feeding cavity and the discharging cavity, the carrying frames are provided with trays, the trays are provided with sample boxes, suction head boxes, reagent boxes and detection carrying plates, and the suction head boxes, the reagent boxes and the detection carrying plates are arranged in the box body. A vibration assembly, a moving mechanism and a carrying mechanism are arranged in the box body, two pipettors are arranged at the moving end of the moving mechanism, the carrying mechanism is used for driving the tray in the feeding cavity to move into the detection cavity, and the carrying mechanism is used for driving the tray in the detection cavity to move into the discharging cavity. According to the antibody detection equipment, the carrying mechanism is utilized, after detection is finished, the carrying mechanism transfers the tray in the detection cavity to the carrying frame of the discharging cavity and transfers the tray in the feeding cavity to the carrying frame of the detection cavity, the replacement time of a sample box, a suction head box, a kit and a detection carrying plate is shortened, and therefore the detection efficiency of the antibody detection equipment is improved.

Description

Technical Field

[0001] The present application relates to the technical field of antibody detection, and in particular to an antibody detection device. Background Art

[0002] Antibody detection equipment is a device used to detect specific antibodies in organisms. By collecting samples such as blood and serum, antibody detection equipment can use immunological principles to quickly and accurately identify and quantify antibody levels. This equipment is widely used in disease diagnosis, epidemic monitoring, immune effect evaluation and other fields.

[0003] At present, the antibody detection equipment includes a detection box, a carrier, a pipetting arm, a pipette, an oscillation module and a waste tank. After the box door is opened, the sample box, the tip box and the reagent box are placed on the carrier, and the pipetting arm drives the pipette to move. The pipette will move into the tip box and drive the tips in the tip box to move. The tips move and absorb the samples and reagents in the sample box and the reagent box respectively. The pipetting arm then drives the pipette to move above the oscillation module, and the pipette squeezes the samples and reagents in the tip into the detection carrier on the oscillation module. The oscillation module drives the detection carrier to vibrate and displays the final test results.

[0004] After the test is completed, the staff opens the box door and needs to take out the sample box, tip box, reagent box and test carrier in turn, and then put the replaced sample box, tip box, reagent box and test carrier back into the box before conducting the test again, which will reduce the detection efficiency. Summary of the invention

[0005] In order to improve the detection efficiency of an antibody detection device, the present application provides an antibody detection device.

[0006] The antibody detection device provided in this application adopts the following technical solution: An antibody detection device comprises a box body, a detection cavity is formed in the middle of the box body, a feed cavity and a discharge cavity are respectively formed on both sides of the box body located in the detection cavity, the box body is located in the detection cavity, and carriers are arranged in the feed cavity and the discharge cavity, a tray is placed on the carrier, and a sample box, a tip box, a reagent kit and a detection carrier are placed on the tray, a vibration component is arranged in the detection cavity, a moving mechanism is arranged in the detection cavity, two pipettes are arranged at the moving end of the moving mechanism, a conveying mechanism is arranged in the box body, the conveying mechanism is used to drive the tray in the feed cavity to move into the detection cavity, and the conveying mechanism is used to drive the tray in the detection cavity to move into the discharge cavity.

[0007] By adopting the above technical solution, the moving mechanism drives the pipette to move, and the pipette is loaded with a pipette tip to absorb samples and reagents, and the samples and reagents are transferred to the detection carrier. The vibration component drives the detection carrier to vibrate and presents the test results. During the antibody detection process, the sample box, pipette tip box, reagent kit and detection carrier that need to be replaced are placed on the tray of the carrier in the feed chamber. When the test is completed, the transport mechanism transfers the tray in the detection chamber to the carrier of the discharge chamber, and transfers the tray in the feed chamber to the carrier of the detection chamber, reducing the replacement time of the sample box, pipette tip box, reagent kit and detection carrier, thereby improving the detection efficiency of the antibody detection equipment.

[0008] Preferably, the transport mechanism includes an X-axis moving component, a Y-axis moving component, a Z-axis moving component and a bracket, the Z-axis moving component is arranged in the detection cavity of the box, the X-axis moving component is arranged at the lifting end of the Z-axis moving component, the Y-axis moving component is arranged at the translation end of the X-axis moving component, the bracket is arranged at the translation end of the Y-axis moving component, and the bracket moves to lift the tray.

[0009] By adopting the above technical solution, the X-axis moving assembly and the Y-axis moving assembly drive the bracket to move under the pallet, and the Z-axis moving assembly drives the bracket to move upward so that the bracket lifts the pallet. After the bracket drives the pallet to move to the designated location, the Z-axis moving assembly drives the pallet to move downward and places the pallet on the carrier, thereby completing the transportation and movement of the pallet.

[0010] Preferably, a storage opening is provided in the bracket, the detection carrier is arranged in the storage opening of the bracket, a hook is provided on the detection carrier for sliding along its own thickness direction, the top of the hook is detachably inserted in the top wall of the bracket, a plurality of first limiting holes are provided on the bottom wall of the detection carrier, a vibration plate is provided on the top of the vibration assembly, a plurality of first limiting rods are provided on the top wall of the vibration plate, and the plurality of first limiting rods are inserted in the plurality of first limiting holes.

[0011] By adopting the above technical solution, the detection carrier is driven to move by the hook during the movement of the pallet. When the pallet is placed on the carrier in the detection chamber, the pallet drives the detection carrier to move to the vibration plate of the vibration assembly. The first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier, so that the detection carrier is placed on the vibration plate more stably. After the detection carrier is placed on the vibration plate, the pallet continues to move downward and is placed on the carrier. At this time, the top of the hook will detach from the pallet, so that the detection carrier is not connected to the pallet, which makes it easier for the vibration assembly to drive the detection carrier to vibrate stably.

[0012] Preferably, the first limit rod is rotatably arranged on the vibration plate, and an elastic reset member for driving the first limit rod to rotate and reset is arranged at the rotation connection between the first limit rod and the vibration plate, a locking block is arranged on the outer wall of the first limit rod, and the detection carrier plate is located on the inner wall of the first limit hole and is obliquely provided with a rotation groove, and the detection carrier plate is located on one side of the top of the rotation groove and is provided with a locking groove connected to the rotation groove, and the locking block is slidably arranged in the rotation groove, and when the locking block slides to the top of the rotation groove, the elastic reset member drives the locking block to move into the locking groove through the first limit rod and locks the detection carrier plate.

[0013] By adopting the above technical solution, when the first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier plate, the locking block on the first limit rod enters the rotation groove and slides. Since the rotation groove is inclined, the locking block will drive the first limit rod to rotate during the sliding process in the rotation groove. When the detection carrier plate is placed on the vibration plate, the locking block moves to the top of the rotation groove, and the elastic reset part drives the first limit rod to rotate and reset. The first limit rod drives the locking block to rotate into the locking groove, so that the locking block can lock the detection carrier plate on the vibration plate, thereby making the vibration plate drive the detection carrier plate to vibrate more stably.

[0014] Preferably, a guide ring is fixedly provided at the bottom of the outer side wall of the hook, a slide groove is opened in the detection carrier, the guide ring is slidably arranged in the slide groove along the thickness direction of the detection carrier, a pull ring is slidably installed on the detection carrier in the slide groove, the pull ring is sleeved on the hook and located above the guide ring, a pull rod is slidably installed in the detection carrier along its own thickness direction, the top end of the pull ring is fixedly connected to the pull ring, and a chamfer is formed on the side of the bottom end of the pull rod close to the locking block, when the tray moves upward, the top end of the hook is inserted into the tray, the tray drives the guide ring to rise through the hook, the guide ring drives the pull rod to rise through the pull ring, the pull rod enters the lock groove and pushes the lock block to slide out of the lock groove through the chamfer.

[0015] By adopting the above technical solution, when the detection carrier is placed on the vibration plate, the hook drives the guide ring to move downward under the action of gravity, the pull ring and the pull rod move downward under the action of gravity, and the bottom end of the pull rod slides out of the lock slot, so that the lock block can enter the lock slot. When the transport mechanism drives the pallet to move, the pallet moves upward, the top end of the hook is inserted into the pallet, the pallet drives the guide ring to rise through the hook, the guide ring drives the pull rod to rise through the pull ring, the pull rod enters the lock slot and pushes the lock block to slide out of the lock slot through the chamfer, so that the detection carrier can be unlocked, so that the pallet can drive the detection carrier to move through the hook.

[0016] Preferably, an elastic member is provided inside the detection carrier plate, a push plate is fixedly provided on the top end of the pull rod, the top end of the elastic member abuts against the inner wall of the detection carrier plate, and the bottom end abuts against the top wall of the push plate.

[0017] By adopting the above technical solution, when the detection carrier is placed on the vibration plate, the elastic member pushes the push plate to move, and the push plate drives the pull rod and the pull ring to move downward, so that the bottom end of the pull ring quickly moves out of the lock groove, thereby facilitating the locking block to enter the lock groove and lock the detection carrier.

[0018] Preferably, a plurality of second limiting rods are fixedly provided on the top wall of the bracket, a plurality of second limiting holes are opened on the bottom wall of the tray, and the plurality of second limiting rods are inserted into the plurality of second limiting holes.

[0019] By adopting the above technical solution, when the bracket lifts the pallet, the multiple second limiting rods on the bracket are inserted into the multiple second limiting holes on the bottom wall of the pallet, thereby limiting the pallet on the bracket, so that when the bracket drives the pallet to move, the pallet is not easily offset.

[0020] Preferably, a plurality of third limiting rods are fixedly provided on the top wall of the carrier, a plurality of third limiting holes are opened on the bottom wall of the tray, and the plurality of third limiting rods are inserted into the plurality of third limiting holes.

[0021] By adopting the above technical solution, when the pallet is placed on the carrier, the multiple third limiting rods on the carrier are inserted into the multiple third limiting holes on the bottom wall of the pallet, thereby limiting the pallet on the carrier, so that the pallet is not easily offset during the detection process of the detection equipment.

[0022] In summary, the present application includes at least one of the following beneficial technical effects: 1. The transport mechanism is used. After the test is completed, the transport mechanism transfers the tray in the test chamber to the carrier of the discharge chamber, and transfers the tray in the feed chamber to the carrier of the test chamber, which reduces the replacement time of the sample box, the tip box, the reagent box and the test carrier, thereby improving the detection efficiency of the antibody detection equipment; 2. With the help of the first limiting rod and the hook, when the tray is placed on the carrier in the detection chamber, the tray drives the detection carrier to move to the vibration plate of the vibration assembly, and the first limiting rod on the vibration plate is inserted into the first limiting hole of the detection carrier, so that the detection carrier is placed on the vibration plate more stably. After the detection carrier is placed on the vibration plate, the tray continues to move downward and is placed on the carrier. At this time, the top of the hook will be separated from the tray, so that the detection carrier is not connected to the tray, so that the vibration assembly can drive the detection carrier to vibrate stably; 3. Through the locking block, when the first limit rod on the vibration plate is inserted into the first limit hole of the detection carrier plate, the locking block on the first limit rod enters the rotation groove and slides. Since the rotation groove is inclined, the locking block will drive the first limit rod to rotate during the sliding process in the rotation groove. When the detection carrier plate is placed on the vibration plate, the locking block moves to the top of the rotation groove, and the elastic reset part drives the first limit rod to rotate and reset. The first limit rod drives the locking block to rotate into the locking groove, so that the locking block can lock the detection carrier plate on the vibration plate, thereby making the vibration plate drive the detection carrier plate to vibrate more stably. BRIEF DESCRIPTION OF THE DRAWINGS

[0023] Figure 1 This is a schematic diagram of the overall structure of the antibody detection device of this application; Figure 2 This is a cross-sectional view of the overall structure of the antibody detection device of this application; Figure 3 This is an exploded cross-sectional view of part of the structure of the antibody detection equipment of this application, in order to highlight the display tray; Figure 4 This is an exploded cross-sectional view of part of the structure of the antibody detection device of this application, in order to highlight the detection carrier; Figure 5 For this application Figure 2 The enlarged schematic diagram at A in the middle; Figure 6 This is a partial structural cross-sectional view of the antibody detection device of the present application, in order to highlight the transport mechanism; Figure 7 For this application Figure 3 The enlarged schematic diagram of point B in the middle; Figure 8 This is an exploded view of part of the structure of the antibody detection equipment in this application, in order to highlight the hook; Fig. 9 This is a partial structural cross-sectional view of the antibody detection device of the present application, in order to highlight the rotating tank; Fig.10 This is a partial structural diagram of the antibody detection device of the present application, in order to highlight the pull rod; Fig.11 This is a partial structural diagram of the antibody detection device of the present application, which is used to highlight the positional relationship between the retractor and the locking block.

[0024] Figure numerals: 1, box; 2, detection chamber; 3, feeding chamber; 4, discharging chamber; 5, carrier; 6, tray; 7, transport mechanism; 71, X-axis moving assembly; 72, Y-axis moving assembly; 73, Z-axis moving assembly; 74, bracket; 8, sample box; 9, tip box; 10, reagent box; 11, detection carrier; 12, vibration assembly; 13, pipette; 14, storage port; 15, hook; 16, first limiting hole; 17, vibration plate; 18, first limiting rod; 19, elastic reset member; 20, locking block; 21 , rotating groove; 22, locking groove; 23, guide ring; 25, pull ring; 26, pull rod; 28, elastic member; 29, push plate; 30, second limiting rod; 31, second limiting hole; 32, third limiting rod; 33, third limiting hole; 34, first door body; 35, second door body; 36, third door body; 37, fourth door body; 38, fifth door body; 39, purification air supply mechanism; 40, air outlet; 41, waste box; 42, pull hook; 43, moving mechanism; 44, lifting assembly; 45, chamfer; 46, guide block. DETAILED DESCRIPTION

[0025] The following is combined with Figure 1-Figure 11 This application is described in further detail.

[0026] The embodiment of the present application discloses an antibody detection device.

[0027] Reference Figure 1 and Figure 2 An antibody detection device includes a box body 1, a detection chamber 2 is formed in the middle of the box body 1, a feed chamber 3 and a discharge chamber 4 connected to the detection chamber 2 are formed on both sides of the box body 1 in the horizontal direction, and a first door body 34, a second door body 35 and a third door body 36 are rotatably installed at the detection chamber 2, the feed chamber 3 and the discharge chamber 4 of the box body 1.

[0028] Reference Figure 2 , Figure 3 and Figure 4 The box body 1 is located in the feeding chamber 3, the detection chamber 2 and the discharging chamber 4, and the carrier 5 is fixedly installed. The tray 6 is detachably placed on the carrier 5. Four third limiting rods 32 are fixedly installed on the top wall of the carrier 5, and four third limiting holes 33 are opened on the bottom wall of the tray 6. The four third limiting rods 32 are respectively inserted into the four third limiting holes 33, so that the tray 6 is stably placed on the carrier 5.

[0029] The tray 6 is provided with a test carrier 11, a plurality of reagent kits 10, a sample box 8 and a tip box 9. The box body 1 is located in the carrier 5 of the test chamber 2 and a vibration assembly 12 is installed therein. The vibration assembly 12 is located directly below the test carrier 11. A vibration plate 17 is fixedly installed on the top of the vibration assembly 12, and four first limit rods 18 are fixedly installed on the vibration plate 17. Four first limit holes 16 are provided on the bottom wall of the test carrier 11, and the four first limit rods 18 are respectively inserted into the four first limit holes 16, so that the test carrier 11 is stably placed on the vibration plate 17. In the present application, the vibration assembly 12 can be selected as an oscillator.

[0030] Reference Figure 2 and Figure 5 The box 1 is located in the detection chamber 2 and is equipped with a moving mechanism 43. Two lifting assemblies 44 are installed at the moving end of the moving mechanism 43. The lifting ends of the two lifting assemblies 44 are fixedly equipped with a pipette 13. In the present application, the moving mechanism 43 can be selected as a three-axis slide, and the moving mechanism 43 can drive the pipette 13 to move freely in the XYZ axis direction. The lifting assembly 44 can be selected as a linear module, and the lifting assembly 44 can drive the pipette 13 to move up and down.

[0031] Reference Figure 2 , Figure 3 and Figure 5 When performing antibody detection on the sample, the moving mechanism 43 first drives the pipette 13 to move above the tip box 9, and the lifting assembly 44 then drives the pipette 13 to move downward, so that the tips in the tip box 9 are installed at the bottom of the two pipettes 13, and then the lifting assembly 44 drives the pipette 13 to rise and reset. The moving mechanism 43 then drives the pipette 13 to move above the sample box 8, and one lifting assembly 44 drives the pipette 13 to move upward and downward, and the pipette 13 absorbs the sample liquid in the sample box 8 into one tip. The moving mechanism 43 then drives the pipette 13 to move above the test box, and another lifting assembly 44 drives another pipette 13 to move upward and downward, and the other pipette 13 absorbs the reagent in the reagent box 10 into another tip.

[0032] The moving mechanism 43 finally drives the pipette 13 to move above the detection carrier 11, and the pipette 13 squeezes the sample liquid and reagent into the detection carrier 11. The vibration component 12 then drives the detection carrier 11 to vibrate through the vibration plate 17, so that the antibody detection result can be displayed. The box body 1 is located in the detection cavity 2 and a waste box 41 is placed. The top opening of the waste box 41 is set. After the pipette 13 squeezes out the sample liquid and reagent, the moving mechanism 43 drives the pipette 13 to move above the waste box 41, and the pipette 13 pushes the two tips to fall into the waste box 41, and the above steps can be repeated to perform antibody detection again.

[0033] Reference Figure 2 and Figure 6A transport mechanism 7 is installed in the box 1, and the transport mechanism 7 includes an X-axis moving assembly 71, a Y-axis moving assembly 72, a Z-axis moving assembly 73 and a bracket 74. The Z-axis moving assembly 73 is installed in the bottom wall of the box 1 located in the detection chamber 2, the X-axis moving assembly 71 is installed at the lifting end of the Z-axis moving assembly 73 and is slidably installed in the bottom wall of the box 1, the Y-axis moving assembly 72 is installed at the translation end of the X-axis moving assembly 71, and the bracket 74 is fixedly installed at the translation end of the Y-axis moving assembly 72. In this application, both the X-axis moving assembly 71 and the Y-axis moving assembly 72 can be selected as linear modules, and the Z-axis moving assembly 73 can be selected as two hydraulic cylinders.

[0034] The X-axis moving assembly 71 and the Y-axis moving assembly 72 can drive the bracket 74 to move freely on the horizontal plane, and the Z-axis moving assembly 73 can drive the bracket 74 to move up and down, so that the two ends of the bracket 74 can simultaneously hold up the tray 6 in the feeding chamber 3 and the detection chamber 2, and transport the tray 6 to the carrier 5 of the detection chamber 2 and the discharge chamber 4. When the detection is completed, the transport mechanism 7 transfers the tray 6 in the detection chamber 2 to the carrier 5 of the discharge chamber 4, and at the same time transfers the tray 6 in the feeding chamber 3 to the carrier 5 of the detection chamber 2, which reduces the replacement time of the sample box 8, the tip box 9, the reagent box 10 and the detection carrier 11, thereby improving the detection efficiency of the antibody detection device.

[0035] Reference Figure 4 and Figure 6 Eight second limiting rods 30 are fixedly mounted on both ends of the top wall of the bracket 74 in the length direction, and four second limiting holes 31 are opened on the bottom wall of the tray 6. When the bracket 74 holds up the tray 6, the four second limiting rods 30 are inserted into the four second limiting holes 31 on the bottom wall of the tray 6, so that the tray 6 can be limited, so that the bracket 74 drives the tray 6 to move more stably.

[0036] Reference Figure 1 and Figure 2 A fourth door 37 is installed in the box body 1 between the detection chamber 2 and the feed chamber 3, and a fifth door 38 is installed in the box body 1 between the detection chamber 2 and the discharge chamber 4. A purification air supply mechanism 39 is installed on the top of the box body 1 above the detection chamber 2. In this application, the purification air supply mechanism 39 can be selected as a FFU laminar air supply unit. Multiple air outlet holes 40 are spaced apart on the side walls of the box body 1 that are located at the feed chamber 3 and the discharge chamber 4 and are far away from each other.

[0037] During the antibody detection process, the fourth door 37 is closed, the fifth door 38 is opened, the bracket 74 is located in the detection chamber 2 and the discharge chamber 4, and the purification air supply mechanism 39 sends the purified air into the detection chamber 2, and the air in the detection chamber 2 is discharged from the air outlet 40 at the bottom of the discharge chamber 4. At this time, the second door 35 can be opened, and the next group of sample boxes 8, pipette tip boxes 9, reagent kits 10 and detection carriers 11 to be tested are placed on the tray 6, and the tray 6 is placed on the carrier 5 of the feed chamber 3.

[0038] Then, the second door 35 is closed, the fourth door 37 is opened, the bracket 74 is moved into the feed chamber 3 and the detection chamber 2, and the fifth door 38 is closed. The third door 36 is opened, and the tray 6 on the carrier 5 in the discharge chamber 4 is taken out. During the antibody detection process, the tray 6 in the feed chamber 3 and the discharge chamber 4 can be replaced, which further improves the efficiency of the antibody detection. At the same time, during the replacement of the tray 6, the purification air supply mechanism 39 sends the purified air into the detection chamber 2, and through the alternating opening and closing of the fourth door 37 and the fifth door 38, the detection chamber 2 is always blocked from the outside air, so that the detection environment is not easily polluted.

[0039] Reference Figure 8 , Fig. 9 and Fig.10 A rectangular storage opening 14 is provided in the tray 6, and the detection carrier 11 is located in the storage opening 14 of the tray 6. Four hooks 15 are slidably installed on the detection carrier 11 along its thickness direction, and the tops of the four hooks 15 are detachably inserted into the top wall of the tray 6. Two guide blocks 46 are symmetrically fixedly installed on the outer wall of the hook 15. The guide blocks 46 are slidably installed in the detection carrier 11 so that the hook 15 will not rotate when it is lifted or lowered. A guide ring 23 is fixedly installed on the side wall of the hook 15 located in the detection carrier 11. A slide groove is provided in the detection carrier 11. The guide ring 23 is slidably installed in the slide groove along the thickness direction of the detection carrier 11 so that the hook 15 will not slip out of the detection carrier 11.

[0040] Reference Figure 3 , Figure 8 , Fig. 9 and Fig.10, during the movement, the tray 6 can drive the detection carrier 11 to move through the four hooks 15. When the bracket 74 drives the tray 6 to be placed on the carrier 5 in the detection chamber 2, the tray 6 drives the detection carrier 11 to move downward. The detection carrier 11 first moves to contact the vibration plate 17 and stops moving. Then the tray 6 continues to move downward and drives the hook 15 to move downward. The hook 15 drives the guide ring 23 to move downward in the slide slot. When the guide ring 23 moves to the bottom of the slide slot, the hook 15 cannot continue to move downward. Finally, the tray 6 continues to move downward to contact the carrier 5 and stops moving. The top of the hook 15 will be separated from the tray 6, so that the detection carrier 11 is not connected to the tray 6, so that the vibration component 12 drives the detection carrier 11 to vibrate, and the vibration of the detection carrier 11 will not be transmitted to the tray 6, so that the detection carrier 11 can vibrate stably.

[0041] Reference Figure 7 The first limit rod 18 is rotatably mounted on the vibration plate 17, and an elastic reset member 19 is installed at the rotation connection between the first limit rod 18 and the vibration plate 17. In the present application, the elastic reset member 19 can be a torsion spring. Two locking blocks 20 are symmetrically fixedly mounted on the outer wall of the first limit rod 18 along its own diameter direction.

[0042] Reference Figure 7 and Fig. 9 The detection carrier 11 is located on the inner wall of the first limiting hole 16 and has two rotation grooves 21 symmetrically formed along the diameter direction of the first limiting hole 16, and the lower half of the rotation groove 21 is inclined. The detection carrier 11 is located at the top of the rotation groove 21 and has a locking groove 22, which is located on the side of the top of the rotation groove 21 away from the inclined direction, and the locking groove 22 is connected to the rotation groove 21, and the two locking blocks 20 are slidably installed in the two rotation grooves 21 and the locking groove 22.

[0043] When the detection carrier 11 is placed on the vibration plate 17, the first limit rod 18 enters the first limit hole 16, and the two locking blocks 20 enter the two rotation grooves 21. During the descent of the detection carrier 11, the locking block 20 slides in the rotation groove 21, and the rotation groove 21 drives the first limit rod 18 to rotate through the locking block 20, and the first limit rod 18 drives the elastic reset member 19 to deform. After the detection carrier 11 is placed on the vibration plate 17, the locking block 20 slides to the top of the rotation groove 21, and the elastic reset member 19 drives the first limit rod 18 to rotate and reset, and the first limit rod 18 drives the two locking blocks 20 to rotate and enter the two locking grooves 22, thereby locking the detection carrier 11 on the vibration plate 17, so that the detection carrier 11 is more stable when vibrating.

[0044] Reference Fig. 9 , Fig.10 and Fig.11, a pull ring 25 is slidably mounted on the hook 15, and the pull ring 25 is slidably mounted in the slide groove of the detection carrier 11, and the pull ring 25 is located above the guide ring 23. Pull rods 26 are slidably mounted on both sides of the pull ring 25 in the detection carrier 11 in the diameter direction, and the pull rods 26 slide in the detection carrier 11 along the thickness direction of the detection carrier 11. A push plate 29 is fixedly mounted on the top of the pull rod 26, and the push plate 29 is fixedly connected to the pull ring 25. An elastic member 28 is installed in the detection carrier 11, and the top end of the elastic member 28 abuts against the inner wall of the detection carrier 11, and the bottom end of the elastic member 28 abuts against the top wall of the push plate 29. In the present application, the elastic member 28 can be selected as a spring.

[0045] Reference Fig.10 and Fig.11 A hook 42 is formed at the bottom of the pull rod 26 , and the hook 42 is located below the locking groove 22 . The pull rod 26 can slide into and out of the locking groove 22 in a vertical direction, and a chamfer 45 is formed on one side of the hook 42 close to the locking block 20 .

[0046] When the detection carrier 11 is suspended in the tray 6 by the hook 15, the push plate 29 moves upward and presses the elastic member 28, and the push plate 29 drives the hook 42 to move into the lock slot 22 through the pull rod 26. When the detection carrier 11 is placed on the vibration plate 17, the elastic member 28 pushes the push plate 29 to move downward, the push plate 29 drives the pull rod 26 and the pull ring 25 to move downward, and the pull ring 25 drives the hook 42 to move downward, so that the hook 42 quickly moves out of the lock slot 22, so that the locking block 20 can enter the lock slot 22 and lock the detection carrier 11.

[0047] When the transport mechanism 7 drives the pallet 6 to move, the pallet 6 moves upward, and the top end of the hook 15 is first inserted into the pallet 6. The pallet 6 drives the guide ring 23 to rise through the hook 15. The guide ring 23 drives the pull rod 26 to rise through the pull ring 25. The pull rod 26 then drives the hook 42 to move upward into the lock slot 22. The hook 42 pushes the lock block 20 to slide out of the lock slot 22 through the chamfer 45, thereby unlocking the detection carrier 11, so that the pallet 6 can drive the detection carrier 11 to move upward through the hook 15.

[0048] The implementation principle of an antibody detection device in an embodiment of the present application is as follows: when performing antibody detection on a sample, the moving mechanism 43 first drives the pipette 13 to move above the tip box 9, and the lifting assembly 44 then drives the pipette 13 to move downward, so that the tips in the tip box 9 are installed at the bottom of the two pipettes 13, and then the lifting assembly 44 drives the pipette 13 to rise and reset. The moving mechanism 43 then drives the pipette 13 to move above the sample box 8, and one lifting assembly 44 drives the pipette 13 to move upward and downward, and the pipette 13 absorbs the sample liquid in the sample box 8 into one tip. The moving mechanism 43 then drives the pipette 13 to move above the test box, and another lifting assembly 44 drives another pipette 13 to move upward and downward, and the other pipette 13 absorbs the reagent in the reagent box 10 into another tip. The moving mechanism 43 finally drives the pipette 13 to move above the detection carrier 11, and the pipette 13 squeezes the sample liquid and reagent into the detection carrier 11. The vibration component 12 then drives the detection carrier 11 to vibrate through the vibration plate 17, so that the antibody detection result can be displayed. After the detection is completed, the transport mechanism 7 transfers the tray 6 in the detection chamber 2 to the carrier 5 of the discharge chamber 4, and at the same time transfers the tray 6 in the feed chamber 3 to the carrier 5 of the detection chamber 2, reducing the replacement time of the sample box 8, the pipette tip box 9, the reagent box 10 and the detection carrier 11, thereby improving the detection efficiency of the antibody detection equipment.

[0049] The above are only optional embodiments of the present disclosure and are not intended to limit the present disclosure. For those skilled in the art, the present disclosure may have various modifications and variations. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present disclosure shall be included in the protection scope of the present disclosure.

Claims

1. An antibody detection device, characterized in that: The invention comprises a box (1), wherein a detection chamber (2) is formed in the middle of the box (1), and a feed chamber (3) and a discharge chamber (4) are respectively formed on both sides of the detection chamber (2) of the box (1), and a carrier (5) is arranged in the detection chamber (2), the feed chamber (3) and the discharge chamber (4) of the box (1), and a tray (6) is placed on the carrier (5), and a sample box (8), a pipette tip box (9), a reagent box (10) and a detection carrier plate (11) are placed on the tray (6), and the box (1) is provided with a plurality of test chambers (11) and a plurality of test chambers (12). ) is provided with a vibration component (12) located in the detection chamber (2), the box body (1) is provided with a moving mechanism (43) located in the detection chamber (2), the moving end of the moving mechanism (43) is provided with two pipettes (13), the box body (1) is provided with a conveying mechanism (7), the conveying mechanism (7) is used to drive the tray (6) in the feeding chamber (3) to move into the detection chamber (2), and the conveying mechanism (7) is used to drive the tray (6) in the detection chamber (2) to move into the discharging chamber (4).

2. An antibody detection device according to claim 1, characterized in that: The transport mechanism (7) comprises an X-axis moving assembly (71), a Y-axis moving assembly (72), a Z-axis moving assembly (73) and a bracket (74); the Z-axis moving assembly (73) is arranged in the detection chamber (2) of the box body (1); the X-axis moving assembly (71) is arranged at the lifting end of the Z-axis moving assembly (73); the Y-axis moving assembly (72) is arranged at the translation end of the X-axis moving assembly (71); the bracket (74) is arranged at the translation end of the Y-axis moving assembly (72); and the bracket (74) moves to lift the tray (6).

3. An antibody detection device according to claim 2, characterized in that: The bracket (74) is provided with a storage opening (14), the detection carrier plate (11) is arranged in the storage opening (14) of the bracket (74), a hook (15) is slidably arranged on the detection carrier plate (11) along its thickness direction, the top of the hook (15) is detachably plugged into the top wall of the bracket (74), a plurality of first limiting holes (16) are provided on the bottom wall of the detection carrier plate (11), a vibration plate (17) is arranged on the top of the vibration component (12), a plurality of first limiting rods (18) are arranged on the top wall of the vibration plate (17), and the plurality of first limiting rods (18) are plugged into the plurality of first limiting holes (16).

4. An antibody detection device according to claim 3, characterized in that: The first limiting rod (18) is rotatably arranged on the vibration plate (17); an elastic reset member (19) for driving the first limiting rod (18) to rotate and reset is arranged at the rotation connection between the first limiting rod (18) and the vibration plate (17); a locking block (20) is arranged on the outer side wall of the first limiting rod (18); a rotation groove (21) is obliquely opened on the inner side wall of the detection carrier (11) located at the first limiting hole (16); a locking groove (22) connected to the rotation groove (21) is opened on one side of the detection carrier (11) located at the top of the rotation groove (21); the locking block (20) is slidably arranged in the rotation groove (21); when the locking block (20) slides to the top of the rotation groove (21), the elastic reset member (19) drives the locking block (20) to move into the locking groove (22) through the first limiting rod (18) and locks the detection carrier (11).

5. An antibody detection device according to claim 4, characterized in that: A guide ring (23) is fixedly arranged at the bottom of the outer wall of the hook (15); a slide groove is provided in the detection carrier (11); the guide ring (23) is slidably arranged in the slide groove along the thickness direction of the detection carrier (11); a pull ring (25) is slidably installed in the slide groove of the detection carrier (11); the pull ring (25) is sleeved on the hook (15) and located above the guide ring (23); a pull rod (26) is slidably installed in the detection carrier (11) along its own thickness direction; the pull ring (25) ) is fixedly connected to the pull ring (25), and a chamfer (45) is formed on the bottom end of the pull rod (26) near the locking block (20). When the tray (6) moves upward, the top end of the hook (15) is inserted into the tray (6), and the tray (6) drives the guide ring (23) to rise through the hook (15), and the guide ring (23) drives the pull rod (26) to rise through the pull ring (25), and the bottom end of the pull rod (26) enters the locking groove (22) and pushes the locking block (20) to slide out of the locking groove (22) through the chamfer (45).

6. An antibody detection device according to claim 5, characterized in that: An elastic member (28) is arranged inside the detection carrier plate (11), and a push plate (29) is fixedly arranged at the top end of the pull rod (26). The top end of the elastic member (28) abuts against the inner wall of the detection carrier plate (11), and the bottom end abuts against the top wall of the push plate (29).

7. An antibody detection device according to claim 2, characterized in that: A plurality of second limiting rods (30) are fixedly arranged on the top wall of the bracket (74), a plurality of second limiting holes (31) are opened on the bottom wall of the tray (6), and the plurality of second limiting rods (30) are inserted into the plurality of second limiting holes (31).

8. An antibody detection device according to claim 1, characterized in that: A plurality of third limiting rods (32) are fixedly arranged on the top wall of the carrier (5), a plurality of third limiting holes (33) are opened on the bottom wall of the tray (6), and the plurality of third limiting rods (32) are inserted into the plurality of third limiting holes (33).

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