Method, device and system for determining extracted electrode voltage

Abstract

The invention relates to an extraction electrode voltage determining method, device and system, a continuous blood glucose monitoring device comprises an extraction electrode, the extraction electrode is attached to the skin surface of a user, and the method comprises the steps that first loading voltage of the extraction electrode is obtained; under the condition that the extraction electrode is loaded with the first loading voltage, the current value of first current flowing through the skin surface of the user is determined; and when the current value of the first current is within a preset current value range, determining the first loading voltage as the loading voltage for an extraction electrode to extract the tissue fluid of the corresponding user.

Description

Technical Field

[0001] The present disclosure relates to blood glucose monitoring technology, and more particularly, to a method, device, and system for determining the voltage of an extraction electrode. Background Art

[0002] Traditional continuous glucose monitoring devices usually measure blood glucose invasively. This not only causes discomfort to patients but also poses an infection risk. Therefore, non-invasive continuous glucose monitoring (CGM) devices are being used by more and more users.

[0003] Currently, non-invasive CGM devices use counter-ion electroosmotic extraction technology for interstitial fluid extraction. This technology generates a corresponding current to form an electric field by applying a certain voltage to the extraction electrode, thereby extracting the interstitial fluid containing glucose. However, there are significant differences in skin impedance and conductivity among different user individuals, resulting in different magnitudes of current being generated on the skin surfaces of different users with the same voltage, affecting interstitial fluid extraction and ultimately the accuracy and stability of the CGM device in detecting blood glucose concentration. Summary of the Invention

[0004] An object of the present invention is to provide a new technical solution for a method of determining the voltage of an extraction electrode.

[0005] According to a first aspect of the present invention, there is provided a method for determining the voltage of an extraction electrode, which is applied to a continuous blood glucose monitoring device. The continuous blood glucose monitoring device includes an extraction electrode attached to the surface of a user's skin. The method includes:

[0006] Obtaining a first loading voltage of the extraction electrode;

[0007] Determining the current value of a first current flowing through the surface of the user's skin when the first loading voltage is applied to the extraction electrode;

[0008] When the current value of the first current is within a preset current value range, determining the first loading voltage as the loading voltage for the extraction electrode to extract the corresponding user's interstitial fluid.

[0009] Optionally, the method further includes:

[0010] When the current value of the first current is not within the preset current value range, adjusting the first loading voltage of the extraction electrode to obtain a second loading voltage of the extraction electrode;

[0011] Determining the current value of a second current flowing through the surface of the user's skin when the second loading voltage is applied to the extraction electrode;

[0012] When the current value of the second current is not within the preset current value range, continue to adjust the second loading voltage of the extraction electrode until the current value of the current flowing through the user's skin surface is within the preset current value range.

[0013] Optionally, the continuous blood glucose monitoring device locally stores the first loading voltages corresponding to different physiological characteristic information. Among them, obtaining the first loading voltage of the extraction electrode includes:

[0014] Obtain the physiological characteristic information input by the user;

[0015] Determine the first loading voltage of the extraction electrode according to the physiological characteristic information input by the user and the first loading voltages corresponding to different physiological characteristic information.

[0016] Optionally, the cloud server stores the first loading voltages corresponding to different physiological characteristic information. Among them, obtaining the first loading voltage of the extraction electrode includes:

[0017] Send a request for obtaining the first loading voltage of the extraction electrode to the terminal device, so that the terminal device sends the request to the cloud server, where the request for obtaining includes the physiological characteristic information input by the user;

[0018] Receive the first loading voltage of the extraction electrode returned by the cloud server, where the first loading voltage of the extraction electrode is determined by the cloud server according to the physiological characteristic information input by the user and the first loading voltages corresponding to different physiological characteristic information.

[0019] Optionally, the continuous blood glucose monitoring device further includes a sampling resistor, and the first current can flow through the sampling resistor. Among them, determining the current value of the first current flowing through the user's skin surface includes:

[0020] Obtain the voltage value across the sampling resistor and the resistance value of the sampling resistor;

[0021] Determine the current value of the first current flowing through the user's skin surface according to the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0022] Optionally, the method further includes:

[0023] Obtain the identity identification information of the user;

[0024] Establish a corresponding relationship between the identity identification information of the user and the loading voltage for the extraction electrode to extract the corresponding user tissue fluid, and store the corresponding relationship.

[0025] Optionally, the method further includes:

[0026] Send the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the terminal device, so that the terminal device sends the obtained user identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the cloud server, and further enables the cloud server to establish a correspondence between the user identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode, and store the correspondence.

[0027] Optionally, the method further includes:

[0028] Determine whether the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time;

[0029] Only when it is determined that the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time, perform obtaining the first loading voltage of the extraction electrode;

[0030] When it is determined that the user is not using the continuous blood glucose monitoring device to monitor blood glucose for the first time, obtain the loading voltage for extracting the tissue fluid by the extraction electrode corresponding to the user;

[0031] Use the loading voltage for extracting the tissue fluid by the extraction electrode corresponding to the user to perform tissue fluid extraction.

[0032] According to a second aspect of the present invention, there is provided a continuous blood glucose monitoring device, including a control unit and an extraction electrode, wherein the extraction electrode is attached to the surface of the user's skin, and wherein,

[0033] The control unit is configured to: obtain the first loading voltage of the extraction electrode; when the extraction electrode is loaded with the first loading voltage, determine the current value of the first current flowing through the surface of the user's skin; when the current value of the first current is within a preset current value range, determine the first loading voltage as the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode.

[0034] According to a third aspect of the present invention, there is provided a continuous blood glucose monitoring system, including: the continuous blood glucose monitoring device as described in the second aspect, a terminal device and a cloud server, wherein,

[0035] The continuous blood glucose monitoring device establishes a communication connection with the terminal device, the terminal device establishes a communication connection with the cloud server, and the terminal device is installed with an APP corresponding to continuous blood glucose monitoring, and wherein,

[0036] The continuous blood glucose monitoring device performs data interaction with the cloud server through the terminal device.

[0037] The method for determining the extraction electrode voltage provided by the present invention can obtain the loading voltage for extracting interstitial fluid by the extraction electrode corresponding to different users, solve the problem of inconsistent interstitial fluid extraction caused by differences in skin impedance and conductivity among different user individuals, and further improve the accuracy and stability of blood glucose concentration detection by a continuous blood glucose monitoring device.

[0038] Through the following detailed description of the exemplary embodiments of this specification with reference to the accompanying drawings, the features and advantages of the embodiments of this specification will become clear. BRIEF DESCRIPTION OF THE DRAWINGS

[0039] The drawings incorporated in and constituting a part of this specification illustrate the embodiments of this specification and, together with the description thereof, are used to explain the principles of the embodiments of this specification.

[0040] Figure 1 is a schematic diagram of a continuous blood glucose monitoring system according to an embodiment of the present invention.

[0041] Figure 2 is a schematic flowchart of a method for determining the extraction electrode voltage according to an embodiment of the present invention.

[0042] Figure 3 is a schematic structural diagram of a continuous blood glucose monitoring device according to an embodiment of the present invention. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0043] Now, various exemplary embodiments of this specification will be described in detail with reference to the accompanying drawings.

[0044] The following description of at least one exemplary embodiment is merely illustrative in nature and in no way serves as a limitation on the embodiments of this specification and their application or use.

[0045] It should be noted that: like reference numerals and letters denote like items in the following drawings, and thus, once an item is defined in one drawing, it does not need to be further discussed in subsequent drawings.

[0046] In an embodiment of the present invention, a method for determining the extraction electrode voltage is provided. This method is applied to a continuous blood glucose monitoring device. The continuous blood glucose monitoring device includes a control unit, an extraction electrode, and an electrochemical sensor. The extraction electrode is attached to the surface of the user's skin. The control unit is used to control the extraction electrode to apply a preset voltage to extract the user's interstitial fluid. Glucose in the interstitial fluid extracted by the extraction electrode can undergo an electrochemical reaction with the reaction enzyme in the electrochemical sensor. The control unit is used to determine the user's blood glucose based on the current generated by the electrochemical reaction.

[0047] According to Figure 1As shown, the continuous blood glucose monitoring device establishes a communication connection with the terminal device, and this communication connection is a wireless connection. For example, it can be a Bluetooth connection or a Wifi connection. The terminal device is installed with an APP (Application) corresponding to continuous blood glucose monitoring. The continuous blood glucose monitoring device performs data interaction with the cloud server through this APP. For example, the continuous blood glucose monitoring device sends the blood glucose value it monitors to the cloud server through this APP, and the cloud server sends the pre-stored device parameters to the corresponding continuous blood glucose monitoring device through this APP.

[0048] According to Figure 2 As shown, the method for determining the extraction electrode voltage in this embodiment includes the following steps S210 to S230.

[0049] Step S210: Obtain the first loading voltage of the extraction electrode.

[0050] In some embodiments, the continuous blood glucose monitoring device locally stores the first loading voltage corresponding to different physiological characteristic information. Step S210 specifically includes: obtaining the physiological characteristic information input by the user; determining the first loading voltage of the extraction electrode according to the physiological characteristic information input by the user and the first loading voltage corresponding to different physiological characteristic information.

[0051] The physiological characteristic information input by the user is an input operation directly performed by the user on the continuous blood glucose monitoring device. Or, the physiological characteristic information input by the user is an input operation performed by the user on the terminal device. According to Figure 1 As shown, the continuous blood glucose monitoring device obtains the physiological characteristic information input by the user through the established communication connection with the terminal device. The physiological characteristic information of the user includes gender and age.

[0052] In this embodiment, the first loading voltage of the extraction electrode is not a randomly obtained voltage, but a voltage obtained based on the physiological characteristic information of the user, so that the obtained first loading voltage of the extraction electrode is closer to the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode, which can reduce the number of operation steps for subsequently determining the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode and improve the efficiency of determining the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode.

[0053] In some embodiments, the cloud server stores the first loading voltage corresponding to different physiological characteristic information. Step S210 specifically includes: sending a request for obtaining the first loading voltage of the extraction electrode to the terminal device, so that the terminal device sends the obtaining request to the cloud server, where the obtaining request includes the physiological characteristic information input by the user; receiving the first loading voltage of the extraction electrode returned by the cloud server, where the first loading voltage of the extraction electrode is determined by the cloud server according to the physiological characteristic information input by the user and the first loading voltage corresponding to different physiological characteristic information.

[0054] The physiological characteristic information input by the user is the information input by the user on the continuous blood glucose monitoring device. As shown in Figure 1 , the continuous blood glucose monitoring device sends a request for obtaining the physiological characteristic information input by the user to the terminal device, so that the terminal device then sends the obtaining request to the cloud server. After receiving the obtaining request, the cloud server determines the first loading voltage of the extraction electrode according to the physiological characteristic information input by the user and the first loading voltage corresponding to different physiological characteristic information, and then sends the first loading voltage of the extraction electrode to the terminal device. The terminal device sends the first loading voltage of the extraction electrode to the continuous blood glucose monitoring device.

[0055] The physiological characteristic information input by the user is the information input by the user on the terminal device. As shown in Figure 1 , the continuous blood glucose monitoring device sends a request for obtaining the first loading voltage of the extraction electrode to the terminal device. After obtaining the obtaining request, the terminal device supplements the physiological characteristic information input by the user into the obtaining request, and sends the obtaining request including the physiological characteristic information input by the user to the cloud server. After receiving the obtaining request, the cloud server determines the first loading voltage of the extraction electrode according to the physiological characteristic information input by the user and the first loading voltage corresponding to different physiological characteristic information, and then sends the first loading voltage of the extraction electrode to the terminal device. The terminal device sends the first loading voltage of the extraction electrode to the continuous blood glucose monitoring device.

[0056] In this embodiment, the first loading voltage of the extraction electrode is not a randomly obtained voltage, but a voltage obtained based on the physiological characteristic information of the user, so that the obtained first loading voltage of the extraction electrode is closer to the loading voltage for extracting the corresponding user tissue fluid by the extraction electrode, which can reduce the number of operation steps for subsequently determining the loading voltage for extracting the corresponding user tissue fluid by the extraction electrode, and improve the efficiency of determining the loading voltage for extracting the corresponding user tissue fluid by the extraction electrode.

[0057] Step S220, in the case where the extraction electrode is loaded with the first loading voltage, determine the current value of the first current flowing through the user's skin surface.

[0058] In some embodiments, the continuous blood glucose monitoring device further includes a sampling resistor, and the first current can flow through the sampling resistor. Step S220 specifically includes: obtaining the voltage value across the sampling resistor and the resistance value of the sampling resistor; determining the current value of the first current flowing through the user's skin surface according to the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0059] The sampling resistor is a high-precision sampling resistor. The control unit of the continuous blood glucose monitoring device pre-stores the resistance value of the sampling resistor. After the control unit obtains the voltage value across the sampling resistor through the Analog-to-Digital Converter (ADC) unit, it determines the current value of the first current flowing through the user's skin surface based on the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0060] Step S230, when the current value of the first current is within the preset current value range, determine the first loading voltage as the loading voltage for the extraction electrode to extract the corresponding user tissue fluid.

[0061] When the current value of the first current is not within the preset current value range, adjust the first loading voltage of the extraction electrode to obtain the second loading voltage of the extraction electrode; when the extraction electrode is loaded with the second loading voltage, determine the current value of the second current flowing through the user's skin surface; when the current value of the second current is not within the preset current value range, continue to adjust the second loading voltage of the extraction electrode until the current value of the current flowing through the user's skin surface is within the preset current value range.

[0062] The preset current value range is a pre-stored numerical range, which can be set according to the tissue fluid extraction requirements.

[0063] When the current value of the first current is not within the preset current value range and the current value of the first current is less than the lower limit value of the preset current value range, increase the first loading voltage of the extraction electrode to obtain the second loading voltage of the extraction electrode. When the current value of the first current is not within the preset current value range and the current value of the first current is greater than the upper limit value of the preset current value range, decrease the first loading voltage of the extraction electrode to obtain the second loading voltage of the extraction electrode.

[0064] The method for determining the extraction electrode voltage provided by the present invention can obtain the loading voltage for the extraction electrode to extract tissue fluid corresponding to different users, solve the problem of inconsistent tissue fluid extraction caused by differences in skin impedance and conductivity of different user individuals, and further improve the accuracy and stability of blood glucose concentration detection by the continuous blood glucose monitoring device.

[0065] In some embodiments, the method further includes: obtaining the identity identification information of the user; establishing a corresponding relationship between the identity identification information of the user and the loading voltage for the extraction electrode to extract the corresponding user tissue fluid, and storing the corresponding relationship.

[0066] The identity identification information of the user is the information input by the user on the continuous blood glucose monitoring device. Storing the corresponding relationship between the identity identification information of the user and the loading voltage for the extraction electrode to extract the corresponding user tissue fluid on the continuous blood glucose monitoring device can directly obtain the loading voltage for the extraction electrode to extract tissue fluid corresponding to the user's identity identification information.

[0067] The user's identity identification information is the information input by the user on the terminal device. The terminal device sends the user's identity identification information to the continuous blood glucose monitoring device, so that the continuous blood glucose monitoring device establishes a corresponding relationship between the user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode, and stores the corresponding relationship. This can directly obtain the loading voltage for extracting tissue fluid by the corresponding extraction electrode according to the user's identity identification information.

[0068] In some embodiments, the method further includes: sending the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the terminal device, so that the terminal device sends the obtained user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the cloud server, and further enabling the cloud server to establish a corresponding relationship between the user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode, and store the corresponding relationship.

[0069] The user's identity identification information is the information input by the user on the continuous blood glucose monitoring device. The continuous blood glucose monitoring device sends the user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the terminal device together, so that the terminal device sends the obtained user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the cloud server.

[0070] The user's identity identification information is the information input by the user on the terminal device. After receiving the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode sent by the continuous blood glucose monitoring device, the terminal device sends the obtained user's identity identification information and the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode to the cloud server.

[0071] In some embodiments, the method further includes: determining whether the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time; in the case of determining that the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time, only then execute obtaining the first loading voltage of the extraction electrode; in the case of determining that the user is not using the continuous blood glucose monitoring device to monitor blood glucose for the first time, obtain the loading voltage for extracting the user's corresponding tissue fluid by the extraction electrode; use the loading voltage for extracting the user's corresponding tissue fluid by the extraction electrode to perform tissue fluid extraction.

[0072] In the case of determining that the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time, it can be determined that the continuous blood glucose monitoring device or the cloud server does not store the loading voltage for extracting the user's corresponding tissue fluid by the extraction electrode, so it is necessary to execute the above steps S210 - S230.

[0073] When it is determined that the user is not using the continuous glucose monitoring device to monitor blood glucose for the first time, it can be determined that the continuous glucose monitoring device or the cloud server does not store the loading voltage for extracting the user's tissue fluid by the extraction electrode. In this way, the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode can be directly obtained from the loading voltages for extracting the tissue fluids of each user by the extraction electrode stored in the continuous glucose monitoring device or the cloud server.

[0074] In this embodiment, by determining whether the user is using the continuous glucose monitoring device for the first time and performing different operations accordingly to obtain the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode, the user experience can be improved and the device performance can be optimized.

[0075] An embodiment of the present invention provides a continuous glucose monitoring device. According to Figure 3 As shown, the continuous glucose monitoring device includes a control unit and an extraction electrode. The extraction electrode is attached to the user's skin surface. The control unit is configured to: obtain the first loading voltage of the extraction electrode; determine the current value of the first current flowing through the user's skin surface when the extraction electrode is loaded with the first loading voltage; and when the current value of the first current is within the preset current value range, determine the first loading voltage as the loading voltage for extracting the corresponding user's tissue fluid by the extraction electrode.

[0076] The control unit is an MCU (Microcontroller Unit).

[0077] According to Figure 3 As shown, the continuous glucose monitoring device further includes a DC / DC conversion unit. The DC / DC conversion unit is connected to the control unit through an IIC interface.

[0078] According to Figure 3 As shown, the continuous glucose monitoring device further includes a sampling resistor, and the first current can flow through the sampling resistor. The control unit is further configured to obtain the voltage value across the sampling resistor and the resistance value of the sampling resistor; and determine the current value of the first current flowing through the user's skin surface according to the voltage value across the sampling resistor and the resistance value of the sampling resistor.

[0079] An embodiment of the present invention provides a continuous glucose monitoring system. According to Figure 1 As shown, the system includes a continuous glucose monitoring device, a terminal device, and a cloud server. The continuous glucose monitoring device establishes a communication connection with the terminal device, the terminal device establishes a communication connection with the cloud server, and the terminal device is installed with an APP corresponding to continuous glucose monitoring.

[0080] The continuous blood glucose monitoring device interacts with the cloud server through this APP. For example, the continuous blood glucose monitoring device sends the blood glucose values it monitors to the cloud server through this APP, and the cloud server sends the pre-stored device parameters to the corresponding continuous blood glucose monitoring device through this APP. By storing and processing data on the cloud server, the integration and intelligent management of data are achieved, facilitating the analysis and optimization of a large amount of device and user data, and further improving the intelligent level of the monitoring system.

[0081] Each embodiment in this specification is described in a progressive manner. For the same or similar parts among the embodiments, reference can be made to each other, and the key point of each embodiment is to illustrate the differences from other embodiments.

[0082] The specific embodiments of this specification have been described above. Other embodiments are within the scope of the appended claims. In some cases, the actions or steps recited in the claims may be executed in a different order than in the embodiments and still achieve the desired results. Additionally, the processes depicted in the figures do not necessarily require the specific order or sequential order shown to achieve the desired results. In certain embodiments, multitasking and parallel processing are also possible or may be advantageous.

[0083] The embodiments of this specification may be systems, methods, and / or computer program products. The computer program product may include a computer-readable storage medium having thereon computer instructions for causing a processor to implement various aspects of the embodiments of this specification.

[0084] A computer-readable storage medium may be a tangible device that can hold and store computer instructions used by a computer instruction execution device. A computer-readable storage medium may be, for example, but not limited to, an electrical storage device, a magnetic storage device, an optical storage device, an electromagnetic storage device, a semiconductor storage device, or any suitable combination of the above. More specific examples (non-exhaustive list) of the computer-readable storage medium include: a portable computer disk, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), a static random access memory (SRAM), a portable compact disc read-only memory (CD-ROM), a digital versatile disc (DVD), a memory stick, a floppy disk, a mechanically encoded device, such as a punched card or raised structures in grooves storing computer instructions, and any suitable combination of the above. The computer-readable storage medium used herein is not construed as an instantaneous signal itself, such as radio waves or other freely propagating electromagnetic waves, electromagnetic waves propagating through a waveguide or other transmission medium (e.g., optical pulses through an optical fiber cable), or electrical signals transmitted through wires.

[0085] The computer instructions described herein can be downloaded from a computer-readable storage medium to various computing / processing devices, or downloaded to an external computer or external storage device via a network, such as the Internet, a local area network, a wide area network, and / or a wireless network. The network can include copper transmission cables, optical fiber transmission, wireless transmission, routers, firewalls, switches, gateway computers, and / or edge servers. A network adapter or network interface in each computing / processing device receives the computer instructions from the network and forwards the computer instructions for storage in a computer-readable storage medium in each computing / processing device.

[0086] The flowcharts and block diagrams in the figures illustrate the architecture, functionality, and operation of possible implementations of systems, methods, and computer program products according to various embodiments of the present specification. In this regard, each block in the flowchart or block diagram may represent a module, a segment of a program, or a portion of computer instructions, which contains one or more executable computer instructions for implementing a specified logical function. In some alternative implementations, the functions noted in the blocks may occur in a different order than noted in the figures. For example, two consecutive blocks may actually be executed substantially in parallel, or they may sometimes be executed in the reverse order, depending on the functions involved. It should also be noted that each block in the block diagrams and / or flowcharts, and combinations of blocks in the block diagrams and / or flowcharts, can be implemented by a dedicated hardware-based system that performs the specified functions or actions, or can be implemented by a combination of dedicated hardware and computer instructions. It is well known to those skilled in the art that implementation by hardware, implementation by software, and implementation by a combination of software and hardware are equivalent.

[0087] The embodiments of the present specification have been described above. The above description is exemplary and not exhaustive, and is not limited to the disclosed embodiments. Many modifications and variations are obvious to those of ordinary skill in the art without departing from the scope of the described embodiments. The choice of terms used herein is intended to best explain the principles of the embodiments, the practical application, or the improvement of the technology in the market, or to enable other ordinary skilled persons in the art to understand the embodiments disclosed herein.

Claims

1. A method for determining an extraction electrode voltage, characterized in that: Applied to a continuous blood glucose monitoring device, the continuous blood glucose monitoring device includes an extraction electrode, the extraction electrode is attached to the user's skin surface, and the method includes: obtaining a first loading voltage of an extraction electrode; When the extraction electrode is loaded with the first loading voltage, determining a current value of a first current flowing through the surface of the user's skin; When the current value of the first current is within a preset current value range, the first loading voltage is determined as a loading voltage for the extraction electrode to extract the corresponding user tissue fluid.

2. The method according to claim 1, characterized in that The method further comprises: When the current value of the first current is not within the preset current value range, adjusting the first loading voltage of the extraction electrode to obtain a second loading voltage of the extraction electrode; When the extraction electrode is loaded with the second loading voltage, determining a current value of a second current flowing through the surface of the user's skin; When the current value of the second current is not within the preset current value range, the second loading voltage of the extraction electrode continues to be adjusted until the current value of the current flowing through the surface of the user's skin is within the preset current value range.

3. The method according to claim 1, characterized in that The continuous blood glucose monitoring device locally stores first loading voltages corresponding to different physiological characteristic information, wherein: The step of obtaining a first loading voltage of the extraction electrode comprises: Obtaining physiological characteristic information input by the user; The first loading voltage of the extraction electrode is determined according to the physiological characteristic information input by the user and the first loading voltage corresponding to the different physiological characteristic information.

4. The method according to claim 1, characterized in that: The cloud server stores the first loading voltage corresponding to different physiological characteristic information, wherein: The step of obtaining a first loading voltage of the extraction electrode comprises: Sending a request for obtaining the first loading voltage of the extraction electrode to the terminal device, so that the terminal device sends the request to the cloud server, wherein the request includes the physiological characteristic information input by the user; Receive the first loading voltage of the extraction electrode returned by the cloud server, wherein the first loading voltage of the extraction electrode is determined by the cloud server according to the physiological characteristic information input by the user and the first loading voltage corresponding to the different physiological characteristic information.

5. The method according to claim 1, characterized in that The continuous blood glucose monitoring device further includes a sampling resistor, through which the first current can flow, wherein determining the current value of the first current flowing through the skin surface of the user includes: Obtaining a voltage value across the sampling resistor and a resistance value of the sampling resistor; The current value of the first current flowing through the surface of the user's skin is determined according to the voltage value across the sampling resistor and the resistance value of the sampling resistor.

6. The method according to claim 1, characterized in that The method further comprises: Obtaining the user's identity information; A corresponding relationship is established between the user's identity information and the loading voltage of the extraction electrode for extracting the corresponding user's tissue fluid, and the corresponding relationship is stored.

7. The method according to claim 1, characterized in that The method further comprises: The loading voltage of the extraction electrode for extracting the corresponding user tissue fluid is sent to the terminal device, so that the terminal device sends the obtained user identity information and the loading voltage of the extraction electrode for extracting the corresponding user tissue fluid to the cloud server, and then the cloud server establishes a corresponding relationship between the user identity information and the loading voltage of the extraction electrode for extracting the corresponding user tissue fluid, and stores the corresponding relationship.

8. The method according to any one of claims 1 to 7, characterized in that: The method further comprises: Determining whether the user is using the continuous blood glucose monitoring device to monitor blood glucose for the first time; The step of obtaining the first loading voltage of the extraction electrode is performed only when it is determined that the user uses the continuous blood glucose monitoring device to monitor blood glucose for the first time; When it is determined that the user is not using the continuous blood glucose monitoring device to monitor blood glucose for the first time, obtaining a loading voltage of an extraction electrode corresponding to the user for extracting tissue fluid; The tissue fluid is extracted by applying a voltage to the extraction electrode corresponding to the user.

9. A continuous blood glucose monitoring device, characterized in that: It includes a control unit and an extraction electrode, wherein the extraction electrode is attached to the surface of the user's skin, wherein: The control unit is used to: obtain a first loading voltage of an extraction electrode; determine a current value of a first current flowing through the surface of the user's skin when the extraction electrode is loaded with the first loading voltage; and determine the first loading voltage as the loading voltage for the extraction electrode to extract the corresponding user tissue fluid when the current value of the first current is within a preset current value range.

10. A continuous blood glucose monitoring system, characterized in that: include: The continuous blood glucose monitoring device, terminal device and cloud server according to claim 9, wherein: The continuous blood glucose monitoring device establishes a communication connection with the terminal device, the terminal device establishes a communication connection with the cloud server, and the terminal device is installed with an APP corresponding to continuous blood glucose monitoring, wherein: The continuous blood glucose monitoring device exchanges data with the cloud server through the terminal device.

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