Cryoablation needle based on radio frequency rewarming

Abstract

The invention relates to the technical field of medical instruments, in particular to a cryoablation needle based on radio frequency rewarming, the medical instrument comprises a needle body, a capillary catheter, a first air inlet pipe, a second air inlet pipe, a needle tube, an insulating tube, a vacuum tube and a radio frequency welding wire, and after the needle body on the needle tube is led into tissue by an operator, the needle body is heated to be cooled; the tissue is frozen after air is injected through the first air inlet pipe and the second air inlet pipe to be cooled, then the tissue is rapidly heated under the action of the radio frequency welding line on the needle tube and is inactivated after multiple times of circulation, treatment is completed, meanwhile, internal redundant tissue fluid is automatically and rapidly guided out through the capillary catheter, secondary infection is avoided, and the device is simple in structure and convenient to operate. The problem of treatment of diseased tissues is effectively solved, and the device has good practicability and economical efficiency and is beneficial to popularization and use of equipment.

Description

Technical Field

[0001] The present invention relates to the technical field of medical devices, and more specifically, to a cryoablation needle based on radio frequency rewarming. Background Art

[0002] The cryoablation technology has experienced four generations of development. From the initial cryosurgery to the current combined hot and cold ablation, the technology has been continuously improved and the treatment effect has been continuously enhanced.

[0003] Currently, the existing cryo needles on the market control the principle and carry out the structural design through the mode of argon refrigeration and helium rewarming. Its helium rewarming mode has a slow heating rate, and the temperature of helium rewarming is generally about 40°C. After the tissue is frozen by argon and then rewarmed by helium, local massive bleeding is likely to occur at the surgical site. At the same time, during the freezing and rewarming processes, the diseased tissue will produce partial exudate, which may cause secondary infection. The storage volume of helium is large, the transportation is extremely inconvenient, and the cost is high. Summary of the Invention

[0004] In order to solve the above problems existing in the prior art, the purpose of the present invention is to provide a cryoablation needle based on radio frequency rewarming with rapid rewarming, avoiding local bleeding problems, small size, and cleaning tissue exudate.

[0005] The technical solution adopted by the present invention is as follows: A cryoablation needle based on radio frequency rewarming includes a needle tube and a needle body blocking one end of the needle tube. An intake pipe one and an intake pipe two are arranged in the inner cavity of the needle tube. An insulating tube is arranged on the outer periphery of the middle part of the needle tube. The intake pipe one and the intake pipe two are provided with a vacuum tube in the inner cavity of the needle tube. The two ends of the vacuum tube are sealed and the inside is hollow. The middle part of the vacuum tube is externally connected to a cryo-outlet protective sleeve away from the working end. The intake pipe one and the intake pipe two penetrate through the cryo-outlet protective sleeve. A radio frequency component is arranged at the end of the needle tube away from the needle body, and the radio frequency component is connected to the needle tube.

[0006] In one embodiment, the end of the needle tube away from the needle body is connected to the middle part of the vacuum tube through the welding point of the needle tube and the vacuum tube.

[0007] In one embodiment, the end part of the intake pipe one between the needle tube and the vacuum tube is bent in a spiral shape. The air outlet port of the intake pipe one is close to the needle body. The intake pipe two spirally wraps around the intake pipe one between the spiral bending part of the intake pipe one and the vacuum tube.

[0008] In one embodiment, the RF component includes an RF connector, and an RF wire on the RF connector is connected to the RF welding wire. The RF wire is used to connect to an RF generating device. A freezing connector is provided at one end of the first intake pipe and the second intake pipe away from the needle body for connecting to a gas supply device.

[0009] In one embodiment, the gas in the inner cavity of the needle tube through the first intake pipe and the second intake pipe is argon.

[0010] In one embodiment, a temperature sensor is provided on the needle body, and the wire of the temperature sensor passes through the inner cavity of the needle tube and extends out.

[0011] In one embodiment, a plurality of capillary liquid guide tubes are further provided on the needle body. The capillary liquid guide tubes penetrate through the needle body. After passing through the inner cavity of the needle tube, the capillary liquid guide tubes continue to pass through the vacuum tube and the gap between the needle tubes, and then are independently led out into a liquid collection device.

[0012] In one embodiment, a handle is provided at one end of the needle tube away from the needle body, and an isolation tube on the handle isolates the direct injection of argon gas to the operator.

[0013] In one embodiment, the RF generating device drives the RF wire to drive the needle tube connected to the RF welding wire to heat up to 60 - 100 °C within 10 - 30 s.

[0014] In one embodiment, the capillary liquid guide tube is made of a metal material.

[0015] The beneficial effects of the present invention are as follows: The present invention is a cryoablation needle based on RF rewarming that has rapid rewarming, avoids local bleeding problems, is small in size, and can clean tissue exudate. The specific implementation manners are as follows:

[0016] After the operator inserts the needle body on the syringe into the lesion area, the control system first drives the high-pressure gas in the freezing joint to flow into the first intake pipe and the second intake pipe, and then continues to flow into the cavity of the syringe lumen of the syringe. Referring to the working principle of throttling expansion, the special high-pressure gas rapidly cools down after passing through the narrow pipe. At the same time, the first intake pipe and the second intake pipe are arranged in a spiral shape, which can accommodate a longer pipeline, causing the air in the pipe to drop sharply, resulting in rapid cooling of the syringe and the needle body. A spiral throttling effect is formed locally in the syringe lumen, enabling the gas to be evenly distributed and flow at the tip of the needle, reducing energy loss. At the same time, the spiral flow channel can change the flow pattern of the fluid in the heat exchange pipe, enhance the turbulence intensity of the fluid, and effectively promote the mixing of the fluid. After a certain period of time, the best cryotherapy effect can be achieved, that is, rapid freezing treatment of the lesion can be realized. After that, the control system closes the gas inlet and instead turns on the radiofrequency joint to convert it into radiofrequency energy output, driving the temperature of the area of the needle body on the syringe to rapidly rewarm to 60 - 100 °C within 10 - 30 seconds, rapidly heating the lesion area, causing the local tumor lesion tissue cells to rupture and thus be eliminated, achieving the treatment effect. After repeating many times, the lesion area is scorched and crusted by high temperature or protein coagulates, effectively solving the problem of local bleeding caused by insufficient helium heating, and at the same time reducing the equipment operation area.

[0017] Since the tissue inevitably causes the intracellular tissue fluid or blood to flow out during cooling and rewarming, and the traditional ablation needle cannot handle it after the outflow, it is prone to contamination after a long time. By setting a capillary liquid guide tube in the needle body, the diameter of the capillary liquid guide tube is extremely small. During the radiofrequency heating of the syringe, the tissue fluid warms up and expands and flows into the capillary liquid guide tube, and then gradually precipitates. Subsequently, the liquid vaporizes or is gradually discharged from the lesion area under the siphon action of the front-end liquid and collected by the collection device, so as to keep the operation area clean after rewarming. After the needle tip detaches from the lesion area, the skin tissue can also quickly close and seal, avoiding secondary infection.

[0018] The device has a simple structure. It uses the spiral structure of the first intake pipe and the second intake pipe to achieve high-quality cooling of the needle body and then cooperates with the radiofrequency system to rapidly rewarm, effectively avoiding the problem of local bleeding in the operation area. At the same time, it uses the effect of high temperature on the tissue waste liquid to make it automatically precipitate quickly through the set capillary liquid guide tube, avoiding the probability of secondary infection, and has good practicability and economy, which is beneficial to the promotion and use of the device. Description of the Drawings

[0019] The following further elaborates on the present invention in detail with reference to the drawings and specific implementation methods.

[0020] Figure 1 It is a partial cross-sectional structure schematic diagram of the present invention;

[0021] Figure 2 It is the second partial cross-sectional structure schematic diagram of the present invention;

[0022] Figure 3 is the third partial sectional structure schematic diagram of the present invention;

[0023] Figure 4 is the sectional structure schematic diagram of the needle body of the present invention;

[0024] Figure 5 is the schematic diagram of the implementation effect of the present invention;

[0025] Figure 6 is the external structure schematic diagram of the present invention.

[0026] Description of the drawings: 1. Needle body; 101. Radio frequency welding point; 102. Ring welding point; 104. Inner cavity of the needle tube; 105. Capillary liquid guide tube; 2. Temperature sensor; 3. First intake pipe; 4. Second intake pipe; 5. Needle tube; 6. Insulating tube; 7. Vacuum tube; 8. Radio frequency welding wire; 9. Handle; 10. Freezing air outlet protection sleeve; 11. Radio frequency wire; 12. Isolation tube; 13. Freezing joint; 14. Radio frequency joint; 16. Freezing area. Detailed implementation manners

[0027] In order to make the objectives, technical solutions and advantages of the present invention clearer and more understandable, the present invention will be further described in detail below in conjunction with the drawings and embodiments. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention, that is, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Usually, the components of the embodiments of the present invention described and shown in the drawings here can be arranged and designed in various different configurations.

[0028] Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed present invention, but only represents the selected embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative efforts fall within the scope of protection of the present invention.

[0029] The following will be combined with Figure 1-6 to illustrate the detailed implementation manners of the present invention. A cryoablation needle based on radio frequency rewarming, referring to Figure 1As shown in the figure, it includes a syringe needle 5 and a needle body 1 that plugs one end of the syringe needle 5. The tip of the needle body 1 is sharp, which is convenient for breaking through tissues. An intake pipe 1 3 and an intake pipe 2 4 are arranged in the inner cavity 104 of the syringe needle 5. An insulating pipe 6 is arranged on the outer peripheral side of the middle part of the syringe needle 5 to prevent touching the syringe needle 5 during operation. The intake pipe 1 3 and the intake pipe 2 4 are provided with a vacuum pipe 7 in the inner cavity 104 of the syringe needle 5. Both ends of the vacuum pipe 7 are sealed and the inside is hollow. Through vacuum heat insulation processing technology, during its use, heat conduction isolation of non-working parts is achieved, ensuring safety and effectiveness during use, reducing the manufacturing and use costs of the cryoablation needle, making it more convenient for the popularization and use of cryoablation, and at the same time, it is easier to ensure the quality of the processed cryoablation needle; the middle part of the vacuum pipe 7 away from the working end is externally connected to a cryo-outlet protective sleeve 10. The intake pipe 1 3 and the intake pipe 2 4 penetrate through the cryo-outlet protective sleeve 10. Advantageously, one end of the syringe needle 5 away from the needle body 1 is connected to the middle part of the vacuum pipe 7 through an annular welding point 102, so that gas can be directly discharged from the cryo-outlet protective sleeve 10. A radio frequency component is arranged at one end of the syringe needle 5 away from the needle body 1, and the radio frequency component is connected to the syringe needle 5.

[0030] Advantageously, referring to Figure 2 As shown in the figure, the end part of the intake pipe 1 3 between the syringe needle 5 and the vacuum pipe 7 is in a spiral bend. The air outlet port of the intake pipe 1 3 is close to the needle body 1. The intake pipe 2 4 spirally wraps around the intake pipe 1 3 between the spiral bend part of the intake pipe 1 3 and the vacuum pipe 7. Further, the gas in the inner cavity 104 of the syringe needle 5 through the intake pipe 1 3 and the intake pipe 2 4 is argon, which is a common gas used in this industry, so it will not be elaborated here. Using the Joule-Thomson valve refrigeration principle, the length of the intake pipe 1 3 and the intake pipe 2 4 is increased by winding directly between the vacuum pipe 7 and the needle body 1. When high-pressure gas passes through, the temperature drops, enabling the needle body 1 and the syringe needle 5 to quickly cool down. At the same time, the spiral flow channel can change the flow pattern of the fluid in the syringe needle 5, enhance the turbulence intensity of the fluid, effectively promote the mixing of the fluid, and accommodate a longer pipeline in a limited space, saving space. Further, referring to Figure 5 , 6 As shown in the figure, a handle 9 is arranged at one end of the syringe needle 5 away from the needle body 1. The isolation pipe 12 on the handle 9 isolates the direct injection of argon gas to the operator.

[0031] Advantageously, referring to Figure 3 As shown in the figure, the radio frequency component includes a radio frequency connector 14. The radio frequency wire 11 on the radio frequency connector 14 is connected to the radio frequency welding wire 8. At the same time, the radio frequency welding wire 8 is connected to the syringe needle 5 through a radio frequency welding point 101. The radio frequency wire 11 is used to connect to a radio frequency generating device. The radio frequency generating device is prior art, so it will not be elaborated here. The intake pipe 1 3 and the intake pipe 2 4 are provided with a cryo-connector 13 at one end away from the needle body 1 for connecting to a gas supply device. The above devices can be independently controlled by a control system to achieve precise control, which is prior art, so it will not be elaborated here.

[0032] Beneficial, referring to Figure 2 As shown, a temperature sensor 2 is provided on the needle body 1. The wire of the temperature sensor 2 passes through the inner cavity 104 of the needle tube and is led out, and then connected to the monitoring device, so as to facilitate real-time observation of the temperature change in the implementation area.

[0033] Beneficial, referring to Figure 4 As shown, a number of capillary liquid guide tubes 105 are also provided on the needle body 1. The number of attached drawings is one, and it can be changed according to the actual use situation. Further, the capillary liquid guide tube 105 is made of a metal material. The capillary liquid guide tube 105 penetrates the needle body 1. After passing through the inner cavity 104 of the needle tube, the capillary liquid guide tube 105 continues to pass through the gap between the vacuum tube 7 and the needle tube 5, and then is independently led out into the liquid collection device.

[0034] In implementation, after the tissue fluid warms up and expands and flows into the capillary liquid guide tube 105, it gradually precipitates. Subsequently, the liquid vaporizes or is gradually discharged from the lesion site by the siphon action of the front-end liquid and is collected by the collection device, so as to keep the local area clean during the operation after rewarming.

[0035] Beneficial, referring to Figure 5 、 6 As shown, the radio frequency generating device drives the radio frequency wire 11 to drive the needle tube 5 connected to the radio frequency welding wire 8 to heat up to 60-100°C within 10-30 s, which can better assist the tissue in the freezing area 16 to heat up and form scabs, avoiding secondary infection.

[0036] The working principle of the present invention:

[0037] After the operator inserts the needle body 1 on the syringe 5 into the lesion area, the control system first drives the high-pressure gas in the freezing joint 13 to flow into the first intake pipe 3 and the second intake pipe 4, and then continues to flow into the cavity 104 of the syringe lumen of the syringe 5. Referring to the working principle of throttling expansion, the special high-pressure gas rapidly cools down after passing through the narrow pipe. At the same time, the first intake pipe 3 and the second intake pipe 4 are arranged in a spiral shape, which can accommodate a longer pipeline, causing the air in the pipe to drop sharply, resulting in rapid cooling of the syringe 5 and the needle body 1. A spiral throttling effect is formed locally in the syringe lumen 104, enabling the gas to be evenly distributed and flow at the tip of the needle, reducing energy loss. At the same time, the spiral flow channel can change the flow pattern of the fluid in the heat exchange pipe, enhance the turbulence intensity of the fluid, and effectively promote the mixing of the fluid. After a certain period of time, the best cryotherapy effect can be achieved, that is, rapid freezing treatment of the lesion can be realized. After that, the control system closes the gas supply and instead turns on the radiofrequency joint 14 to convert it into radiofrequency energy output, driving the temperature of the area of the needle body 1 on the syringe 5 to rapidly rewarm to 60 - 100 °C within 10 - 30 seconds, rapidly raising the temperature of the lesion, causing the local tumor lesion tissue cells to rupture and be eliminated, achieving the treatment effect. After repeating multiple times, the lesion is scorched and crusted by high temperature or protein coagulates, effectively solving the problem of local bleeding caused by insufficient helium gas warming, and at the same time reducing the equipment operation area.

[0038] Since the outflow of intracellular tissue fluid or blood is inevitable when the tissue cools down and rewarms, and the traditional ablation needle cannot handle it after the outflow, it is easy to produce contamination after a long time. By setting a capillary liquid guide tube 105 in the needle body 1, the diameter of the capillary liquid guide tube 105 is extremely small. During the radiofrequency warming of the syringe 5, after the tissue fluid warms up and expands and flows into the capillary liquid guide tube 105, it gradually precipitates, and the subsequent liquid vaporizes or is gradually discharged from the lesion by the siphon action of the front-end liquid and collected by the collection device, so as to keep the operation area clean after rewarming. After the needle head detaches from the lesion, the skin tissue can also quickly close and seal, avoiding secondary infection.

[0039] In the description of the present invention, it should be noted that unless otherwise clearly specified and limited, terms such as "installation", "connection", and "connection" should be understood in a broad sense. For example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be directly connected or indirectly connected through an intermediate medium, and it can be the communication inside two components. For those of ordinary skill in the art, the specific meanings of the above terms in the present invention can be understood according to specific situations.

[0040] The above content is only an example and explanation of the structure of the present invention. Those skilled in the technical field of the present invention can make various modifications or supplements to the described specific embodiments or use similar methods for substitution. As long as it does not deviate from the structure of the invention or exceed the scope defined by this claim book, it shall fall within the protection scope of the present invention.

Claims

1. A cryoablation needle based on radiofrequency rewarming, characterized in that: The invention comprises a needle tube (5) and a needle body (1) for sealing one end of the needle tube (5); an air inlet pipe (3) and an air inlet pipe (4) are arranged in the needle tube inner cavity (104) of the needle tube (5); an insulating tube (6) is arranged on the outer side of the middle part of the needle tube (5); the air inlet pipe (3) and the air inlet pipe (4) are arranged in the needle tube inner cavity (104); the vacuum tube (7) is sealed at both ends and is hollow inside; the middle part of the vacuum tube (7) is connected to a refrigerated air outlet sheath tube (10) away from the working end; the air inlet pipe (3) and the air inlet pipe (4) penetrate the refrigerated air outlet sheath tube (10); a radio frequency component is arranged at one end of the needle tube (5) away from the needle body (1); and the radio frequency component is connected to the needle tube (5).

2. The cryoablation needle based on radiofrequency rewarming according to claim 1, characterized in that: One end of the needle tube (5) away from the needle body (1) is connected to the middle part of the vacuum tube (7) via a welding point between the needle tube (5) and the vacuum tube (7).

3. The cryoablation needle based on radiofrequency rewarming according to claim 1, characterized in that: The end portion of the air inlet pipe 1 (3) between the needle tube (5) and the vacuum tube (7) is spirally bent, the air outlet port of the air inlet pipe 1 (3) is close to the needle body (1), and the air inlet pipe 2 (4) is spirally wrapped around the air inlet pipe 1 (3) between the spirally bent portion of the air inlet pipe 1 (3) and the vacuum tube (7).

4. The cryoablation needle based on radiofrequency rewarming according to claim 1, characterized in that: The radio frequency component comprises a radio frequency connector (14), the radio frequency line (11) on the radio frequency connector (14) is connected to the radio frequency welding line (8), the radio frequency line (11) is used to connect to a radio frequency generating device, and the ends of the air inlet pipe 1 (3) and the air inlet pipe 2 (4) away from the needle body (1) are provided with a freezing connector (13) for connecting to a gas supply device.

5. The cryoablation needle based on radiofrequency rewarming according to claim 4, characterized in that: The gas in the needle tube inner cavity (104) passing through the first air inlet pipe (3) and the second air inlet pipe (4) is argon gas.

6. The cryoablation needle based on radiofrequency rewarming according to claim 1, characterized in that: The needle body (1) is provided with a temperature sensor (2), and a lead wire of the temperature sensor (2) passes through the inner cavity (104) of the needle tube and is led out.

7. The cryoablation needle based on radiofrequency rewarming according to claim 1, characterized in that: The needle body (1) is also provided with a plurality of capillary liquid guide tubes (105), which penetrate the needle body (1). After passing through the inner cavity (104) of the needle tube, the capillary liquid guide tubes (105) continue to pass through the gap between the vacuum tube (7) and the needle tube (5), and then are independently led out to the liquid collection device.

8. The cryoablation needle based on radiofrequency rewarming according to claim 5, characterized in that: A handle (9) is provided at one end of the needle tube (5) away from the needle body (1), and an isolation tube (12) on the handle (9) isolates the argon gas from being directly sprayed toward the operator.

9. The cryoablation needle based on radiofrequency rewarming according to claim 4, characterized in that: The radio frequency generating device drives the radio frequency line (11) to drive the needle tube (5) connected to the radio frequency welding line (8) to heat up to 60-100° C. within 10-30 seconds.

10. The cryoablation needle based on radiofrequency rewarming according to claim 7, characterized in that: The capillary liquid guide tube (105) is made of metal material.

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