Sequencer use guiding method and device

Abstract

The invention discloses a sequencer use guiding method and device. The method comprises: displaying main page information of a sequencer on a main screen (S100); a target state information set is collected and detected in real time, auxiliary information corresponding to the target state information set is determined under the condition that it is detected that the target state information set meets auxiliary screen triggering conditions, and the target state information set comprises component state information and / or page state information corresponding to main screen display content. The auxiliary information comprises at least one of sequencer state prompt information and operation guidance information (S110); and controlling the secondary screen to display the auxiliary information (S120).

Description

Technical Field

[0001] This application relates to the field of measurement and control technology, for example, it relates to a method and device for guiding the use of a sequencer, a sequencer, a medium and a product. Background Art

[0002] With the rapid development of gene sequencing technology, the functions of sequencers have become increasingly complex. There are obvious differences in the operation interfaces and processes of different products, which increases the learning cost of users. At the same time, the operation of sequencers is highly specialized. Users need to gradually understand a series of operations such as consumable loading, operation process, and chamber door closing through cumbersome instructions, and the instructions often cannot cover diverse scenarios in actual use. In addition, the operation interface is information-intensive and the feedback form is single, so users are prone to missing key steps or making mistakes.

[0003] In summary, there is a problem of high usage difficulty in existing sequencers. Summary of the Invention

[0004] This application provides a method and device for guiding the use of a sequencer, a sequencer, a medium and a product, which reduces the difficulty for users to use a sequencer for gene sequencing.

[0005] An embodiment of this application provides a method for guiding the use of a sequencer. The sequencer includes a main screen and a secondary screen, and the method includes: displaying main page information of the sequencer on the main screen; collecting and detecting a set of target status information in real time, and when it is detected that the set of target status information meets the secondary screen trigger condition, determining auxiliary information corresponding to the set of target status information. The set of target status information includes at least one of component status information and page status information corresponding to the content displayed on the main screen. The auxiliary information is different from the main page information displayed on the main screen; controlling the secondary screen to display the auxiliary information; the auxiliary information includes at least one of the following displayed on the secondary screen: sequencer status prompt information, operation guide information; the sequencer status prompt information is configured to present the working status of a specified component of the sequencer; the operation guide information includes at least one of guiding text, icons and videos for the user to operate the sequencer.

[0006] An embodiment of the present application provides a guiding device for a sequencer. The sequencer includes a main screen and a secondary screen. The device includes a main screen module, an auxiliary information module, and a display module. The main screen module is coupled to the main screen to control the main screen to display the main page information of the sequencer. The auxiliary information module has an input / output (I / O) acquisition unit for real-time acquisition and detection of a set of target status information. When the I / O acquisition unit detects that the set of target status information meets the secondary screen trigger condition, the auxiliary information module determines the auxiliary information corresponding to the set of target status information. The set of target status information includes at least one of component status information and page status information corresponding to the content displayed on the main screen. The auxiliary information is different from the main page information displayed on the main screen. The display module is coupled to the secondary screen to control the secondary screen to display the auxiliary information.

[0007] An embodiment of the present application provides a nucleic acid sequencing device, including: a stage configured to carry a sample to be detected; a fluid system configured to provide various reagents for a detection reaction to the sample to be detected, and the sample to be detected undergoes the detection reaction with the various reagents to generate a detectable signal; a detection system configured to detect the detectable signal; and a user guidance system including a main screen and a secondary screen; and a processor operably coupled to the user guidance system. The processor, based on the operation of at least one of the stage, the fluid system, and the detection system, calls a main module to control the operation of the nucleic acid sequencing device. During the operation of the main module, a first module is called to control the main screen to display main page information, and a second module is called to control the secondary screen to display auxiliary information different from the main page information. The first module and the second module are independent of each other.

[0008] An embodiment of the present application provides a display method for a nucleic acid sequencing device. The nucleic acid sequencing device includes: a stage configured to carry a sample to be detected; a fluid system configured to provide various reagents for a detection reaction to the sample to be detected, and the sample to be detected undergoes the detection reaction with the various reagents to generate a detectable signal; a detection system configured to detect the detectable signal; a user guidance system including a main screen, a secondary screen, and a processor. The display method is configured to be executed by the processor and includes: displaying main page information of the nucleic acid sequencing device on the main screen; collecting and detecting a set of target status information, and when it is detected that the set of target status information meets the secondary screen trigger condition, determining auxiliary information different from the main page information corresponding to the set of target status information. The auxiliary information includes at least one of a sequencer status prompt information and an operation guidance information; the sequencer status prompt information is configured to present the working status of a specified component of the sequencer; the operation guidance information includes at least one of guidance text, icons, and videos for the user to operate the sequencer; controlling the secondary screen to display the auxiliary information.

[0009] An embodiment of the present application provides a sequencer, including: a main screen configured to display main screen display content; a secondary screen configured to output auxiliary information; a plurality of components, and some or all of the plurality of components can be used in cooperation to complete the sequencing operations of multiple sequencing nodes in the sequencing process; at least two component status information determination units configured to determine the component status information of the corresponding components; a page status information determination unit configured to determine the page status information corresponding to the main screen display content; a processor configured to execute the sequencer usage guidance method described in any embodiment.

[0010] An embodiment of the present application provides an electronic device, which includes: at least one processor; and a memory communicatively connected to the at least one processor; wherein, the memory stores a computer program executed by the at least one processor, and the computer program is executed by the at least one processor so that the at least one processor can execute the sequencer usage guidance method described in any embodiment of the present application or the display method of the nucleic acid sequencing device described in any embodiment of the present application.

[0011] An embodiment of the present application provides a computer-readable storage medium storing computer instructions for causing a processor to execute the sequencer usage guidance method described in any embodiment of the present application or the display method of the nucleic acid sequencing device described in any embodiment of the present application when executed.

[0012] An embodiment of the present application provides a computer program product, which includes a computer program that, when executed by a processor, implements the sequencing instrument usage guiding method described in any embodiment or the display method of the nucleic acid sequencing device described in any embodiment. Description of the Drawings

[0013] Figure 1 is a flowchart of the sequencing instrument usage method provided by an embodiment of the present application;

[0014] Figure 2 is another flowchart of the sequencing instrument usage method provided by an embodiment of the present application;

[0015] Figure 3 is another flowchart of the sequencing instrument usage method provided by an embodiment of the present application;

[0016] Figure 4A is a schematic diagram of a sequencing instrument with the main screen lifted and the A-side door open provided by an embodiment of the present application;

[0017] Figure 4B is a display schematic diagram of the main screen and the secondary screen provided by an embodiment of the present application;

[0018] Figure 4C is a display schematic diagram of the secondary screen provided by an embodiment of the present application;

[0019] Figure 4D is another display schematic diagram of the secondary screen provided by an embodiment of the present application;

[0020] Figure 4E is another display schematic diagram of the secondary screen provided by an embodiment of the present application;

[0021] Figure 5 is an auxiliary information schematic diagram provided by an embodiment of the present application;

[0022] Figure 6 is another auxiliary information schematic diagram provided by an embodiment of the present application;

[0023] Figure 7 is another flowchart of the sequencing instrument usage method provided by an embodiment of the present application;

[0024] Figure 8 is another auxiliary information schematic diagram provided by an embodiment of the present application;

[0025] Figure 9 is another auxiliary information schematic diagram provided by an embodiment of the present application;

[0026] Figure 10 is a flowchart for determining auxiliary information provided by an embodiment of the present application;

[0027] Figure 11A is a schematic structural diagram of a sequencing instrument usage guiding device provided according to an embodiment of the present application;

[0028] Figure 11B is another schematic structural diagram of a sequencing instrument usage guiding device provided according to an embodiment of the present application;

[0029] Figure 12 is a schematic structural diagram of a nucleic acid sequencing device provided according to an embodiment of the present application;

[0030] Figure 13A is a control block diagram of a sequencing instrument provided according to an embodiment of the present application;

[0031] Figure 13B is another control block diagram of a sequencing instrument provided according to an embodiment of the present application;

[0032] Figure 13C is a schematic diagram of the connection relationship of multiple I / O interfaces provided according to an embodiment of the present application;

[0033] Figure 14 is another schematic structural diagram of a sequencing instrument provided according to an embodiment of the present application;

[0034] Figure 15 is a schematic structural diagram of an electronic device for implementing the sequencing instrument guiding method of the embodiment of the present application. Detailed implementation manners

[0035] Next, the technical solutions in the embodiments of the present application will be described in conjunction with the accompanying drawings in the embodiments of the present application. Obviously, the described embodiments are only a part of the embodiments of the present application, rather than all the embodiments. Based on the embodiments in the present application, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present application.

[0036] It should be noted that the terms "first", "second", etc. in the specification and claims of the present application and the above accompanying drawings are used to distinguish similar objects, and do not necessarily need to describe a specific order or sequence. It should be understood that such used data can be interchanged under appropriate circumstances so that the embodiments of the present application described herein can be implemented in an order other than those illustrated or described herein. In addition, the terms "including" and "having" and any variations thereof are intended to cover non-exclusive inclusion. For example, a process, method, system, product or device including a series of steps or units does not necessarily need to be limited to those clearly listed steps or units, but may include other steps or units not clearly listed or inherent to these processes, methods, products or devices.

[0037] Figure 1The flowchart of the usage guidance method for a sequencer provided by an embodiment of the present application. This embodiment is applicable to a sequencer including a main screen and a secondary screen; for example, it is applicable to the situation where auxiliary information associated with the current state of the sequencer is displayed on the secondary screen to guide the user to correctly use the sequencer. This method can be executed by a sequencer usage guidance device, which can be implemented in the form of hardware and / or software, and the sequencer usage guidance device can be configured in the processor of the sequencer.

[0038] Combined with Figure 4A and Figure 12 As shown, the sequencer includes: a stage 70, a fluid system 71, and a detection system 72. The stage 70 has a chip platform 69, and a sequencing chip carrying a sample to be detected is installed on and supported by the chip platform 69. The fluid system 71 provides various reagents to the sample to be detected on the sequencing chip, and the sample to be detected reacts with the various reagents to generate a detectable signal. This detectable signal is detected by the detection system 72, and the detection system 72 can be, for example, a Time Delay Integration (TDI) camera, and this detectable signal is, for example, a fluorescence signal. The sequencer usage guidance device includes a user guidance system having a main screen 61 and a secondary screen 62, and a processor 60. The above-mentioned sequencer usage guidance device can be integrated in the processor 60.

[0039] Combined with Figure 1 As shown, the usage guidance method for a sequencer provided by an embodiment of the present application includes:

[0040] S100. Display the main page information of the sequencer on the main screen 61; S110. Real-time collect and detect the target status information set, and when it is detected that the target status information set meets the secondary screen trigger condition, determine the auxiliary information corresponding to the target status information set. The target status information set includes component status information and / or page status information corresponding to the content displayed on the main screen. The auxiliary information is different from the main page information and includes sequencer status prompt information and / or operation guidance information; and, S120. Control the secondary screen 62 to display the auxiliary information. The sequencer status prompt information is configured to present the working status of a specified component of the sequencer; the operation guidance information includes guidance text, icons, and / or videos for the user to operate the sequencer. The operation guidance information is, for example, prompt information associated with the current sequencing node and / or prompt information corresponding to the next sequencing step.

[0041] The main page information includes, for example, overall progress information, which can be understood as the overall progress of the sequencer performing nucleic acid detection on the current sample to be detected, including the completion status of multiple links and overall time plans and other information. As Figure 4A , Figure 4BAs shown, the chip platform 69 includes two chip positions A and B. The main page information is displayed on the main screen 61, showing the sequencing progress of the sequencing chips on the two chip positions A and B respectively. The auxiliary information is displayed on the secondary screen 62 below the main screen 61, such as the operation guide information composed of text and icons shown Figure 4B as shown.

[0042] The page status information is a software variable status information, which is associated with the content displayed on the main screen. Different main screen display contents correspond to different page status information.

[0043] The sequencer includes hardware components and software components. The hardware components correspond to the hardware structure (such as the above-mentioned stage 70, fluid system 71, and detection system 72), and the software components correspond to software modules or software units (such as software with functions such as base recognition and bioinformatics analysis). The component status information is used to reflect the current status of the components, such as the movement-in-place status, whether the target information is missing, etc.

[0044] Exemplarily, 01 is used to represent that the main screen 61 rises to the first target position, 10 is used to represent that the chamber doors 65 / 66 are opened, 00 is used to represent that the base information of the sample chip is successfully read, and 11 is used to represent that the base information of the sample chip is read failed. Here, 01 and 10 are the component status information for the main screen 61 and the chamber doors 65 / 66 respectively, and 00 and 11 are both the component status information for the sample chip.

[0045] About the target state information set. In one embodiment, the current target state information set is determined based on a predetermined logic and component state information and / or page state information associated with the current interactive operation, and the interactive operation is a software interactive operation or a hardware interactive operation. The software interactive operation is an interactive operation based on the content displayed on the main screen, and the hardware interactive operation is an interactive operation performed through the hardware structure, such as a sequencing start button, opening a door, consumables placement behavior, closing a door, and descending a screen. The association with the current interactive operation can be understood as the component state information and / or page state information associated with the most recent interactive operation. Exemplarily, the user performs a software interactive operation for the main screen to rise based on the content displayed on the main screen, then the component state information directly associated with the software interactive operation includes component state information for reflecting whether the main screen has moved into place, and page state information directly associated with the software operation. The page state information corresponds to the main screen display content generated by the interactive operation. Since the main screen rises into place, the warehouse door can be automatically triggered to open, so the warehouse door state information for reflecting the movement of the warehouse door into place is indirectly associated with the software interactive operation. Therefore, the first target state information set corresponding to the software interactive operation includes the main screen state information and page state information directly generated by the software interactive operation; after the first target state information, the second target state information set corresponding to the software interactive operation includes the main screen state information, page state information and warehouse door state information indirectly generated between the software interactive operations. This embodiment realizes the inference of the task that the user is about to perform at this time based on the current interactive operation and the predetermined logic, and calls out the auxiliary information for the task in real time, which can accurately provide the auxiliary information required by the user. Optionally, when the collected target state set includes multiple target state information that meet the secondary screen triggering conditions and are generated at the same time, the corresponding auxiliary information is determined to be displayed on the secondary screen 62 according to the preset target state information priority. The auxiliary information corresponding to the target state information with the highest priority can be selectively displayed, or the corresponding multiple auxiliary information can be sequentially displayed on the secondary screen 62 in the order of the priority.

[0046] As a highly precise device, a sequencer includes multiple components, and the component status information of each of the multiple components is obtainable. For a sequencer in the working state, the component status information of each component can be obtained on demand or in real time. Additionally, whether the content displayed on the main screen changes, or even whether a target change occurs, can be reflected by the page status information. Therefore, by means of a set of target status information including the page status information and / or the component status information, it is possible to determine the current operation node where the sequencer is located or the current interaction content on the main screen, thereby controlling the secondary screen to display auxiliary information corresponding to the operation node or the interaction content. This not only separates the display screens for the auxiliary information and the non-auxiliary information, but also enables the user to accurately lock in on the auxiliary information and quickly and accurately execute the operation content of the next step based on the auxiliary information, greatly reducing the difficulty of using the sequencer.

[0047] The auxiliary information is an animation clip or a target image, and the target image includes icons and / or text information. For example, the auxiliary information may be explanatory information for key content in the content displayed on the main screen, or a reminder message corresponding to the content displayed on the main screen, or a prompt message for the next operation step, etc. Taking the content displayed on the main screen as the sample loading prompt message as an example, the auxiliary information includes an image of the sample placement position and / or an example image of incorrect placement posture.

[0048] If the auxiliary information is a video, in theory, it can be configured as video data in any format; if the auxiliary information is an image, in theory, it can be configured as image data in any format. In one embodiment, the auxiliary information is in the MP4 format or the GIF format. If the auxiliary information is in the MP4 format, the secondary screen program calls an MP4 player to play the auxiliary information and controls the secondary screen to display the playing process of the auxiliary information; if the auxiliary information is in the GIF format, the secondary screen program calls a GIF player to play the auxiliary information and controls the secondary screen to display the playing process of the auxiliary information.

[0049] The main screen 61 is configured to display the content displayed on the main screen (i.e., the main page information). In some scenarios, the content displayed on the main screen includes, but is not limited to, at least one of controls, text information, and schematic diagrams.

[0050] The main screen 61 and the secondary screen 62 can be controlled by one program or by two programs respectively. In this embodiment, the latter is selected. In view of this, based on the secondary screen program corresponding to the secondary screen 62, the secondary screen is controlled to output the current auxiliary information so that the user can accurately learn the prompt information for the current sequencing node, the content of the next sequencing step, or other customized content according to the auxiliary information. As Figure 4C shown, the auxiliary information displayed on the secondary screen can be a sequencer status prompt message triggered by a change in the status of the sequencer components (such as a hardware status reminder taking the fluid system as an example, a software status reminder taking the storage space status as an example, etc.). As Figure 4DThe auxiliary information displayed on the secondary screen can be operation guidance information that prompts key nodes of the sequencer (such as key operation parameter reminders, key operation process reminders, etc.). For example, Figure 4D As shown, the auxiliary information can also be customized icon information.

[0051] The above-mentioned main page information is displayed on the main screen based on the main screen program corresponding to the main screen 61. Optionally, the processor controls the main screen and the secondary screen to simultaneously display the main screen display content and the auxiliary information through the main screen program and the secondary screen program respectively, realizing the separate control of the display content of the main screen 61 and the secondary screen 62, and reducing the difficulty of controlling the main screen and the secondary screen.

[0052] When the processor 60 detects a change in the main screen display content, it updates the page status information corresponding to the main screen display content in the cache. Optionally, the processor executes the following steps through the main screen program: when detecting the parameter information indicating a change in the main screen display content, it updates the page status information corresponding to the main screen display content in the cache; correspondingly, through the secondary screen program corresponding to the secondary screen, when detecting a change in the page status information corresponding to the main screen display content in the cache, it determines the auxiliary information identifier corresponding to the updated page status information, reads the auxiliary information corresponding to the auxiliary information identifier from a predetermined storage location, and then controls the secondary screen to display the auxiliary information.

[0053] The application program of the sequencer is installed in the program installation directory. During the operation of the application program, it calls the main screen program to complete the control of the main screen and calls the secondary screen program to complete the control of the secondary screen. The predetermined storage location can be optionally located in the program installation area, and the program arrangement area is located in the system disk. The sequencer also includes a data disk, which is configured to store sequencing data.

[0054] In the technical solution of the sequencer usage guidance method provided by the embodiments of the present application, since the auxiliary information includes sequencer status prompt information and / or operation guidance information, by the way of displaying the auxiliary information associated with the target status information set on the secondary screen and displaying the main page information on the main screen, it not only separates the main page information and the display screen where the auxiliary information is located, but also enables the user to accurately lock the auxiliary information and quickly and accurately execute the operation content of the next step according to the auxiliary information. Therefore, the usage difficulty of the sequencer is greatly reduced, and the usage experience of the sequencer is improved.

[0055] Figure 2 It is another flowchart of the sequencer usage guidance method provided by the embodiments of the present application. In this embodiment, the determination step of the auxiliary information is refined on the basis of the foregoing embodiment. For example, Figure 2As shown, the method includes: S2101, in response to a trigger operation on a target control in the main screen 61, determining the main screen display content and updating the page state information corresponding to the main screen display content according to the main screen display content; S2102, when it is detected that the page state information corresponding to the main screen display content is updated, determining the auxiliary information corresponding to the updated page state information; and S220, controlling the secondary screen 62 to display the auxiliary information.

[0056] A control is an element in the user interface that is configured to receive user input, display information, and perform functions. They are the basic components for constructing the user interface and realize the functions and operations of the software through interaction with users. A trigger operation is an operation used to trigger a control, such as a click, touch, etc. As Figure 4B shown, the user clicks on a specified button in the upper right corner of the main page to trigger the secondary screen to display the corresponding auxiliary information.

[0057] When the processor 60 detects a trigger operation on a target control in the main screen, it can determine the main screen display content, and the main screen display content is different from the auxiliary information. After the main screen display content is determined, the processor 60 updates the page state information corresponding to the main screen display content in the cache according to the main screen display content. After the updated page state information is determined, the auxiliary information associated with the updated page state information is determined, and the secondary screen 62 is controlled to display the auxiliary information. This embodiment can infer the task that the user is about to perform at this time based on the click event on the main screen display content, and display the auxiliary information on the secondary screen independent of the main screen to guide the user on how to operate, and can accurately provide the user with the required auxiliary information, such as key icon animation clips, without the user having to repeatedly look back at the device usage video content to find the required clips, nor interrupt the current sequencing operation process; moreover, this embodiment can provide real-time and panoramic guidance and feedback for both the onboarding and offboarding interaction operations.

[0058] Combined Figure 13B As shown, in one embodiment, S2101 is executed based on the main screen program 602 corresponding to the main screen, and S2102 and S220 are executed based on the secondary screen program 603 corresponding to the secondary screen 62. The main screen program 602 is only used to process information related to the main screen control and does not process information related to the secondary screen 603 control. Therefore, the main screen program 602 is used to execute the following steps: obtaining a trigger operation on a control in the main screen 61, determining the main screen display content, and updating the page state information corresponding to the main screen display content in the cache according to the main screen display content to ensure that the page state information can be determined at a relatively fast speed. The secondary screen program 603 corresponding to the secondary screen 62 is used to execute the following steps: real-time detection of the buffer area (i.e., Figure 13BDetermine whether the page status information corresponding to the main screen display content in the status register 605 shown in the figure has changed. When the page status information corresponding to the main screen display content changes, determine that the page status information meets the secondary screen trigger condition, determine the auxiliary information based on the page status information after the change, and control the secondary screen 62 to display the auxiliary information. Through the cooperation of the main screen program 602 and the secondary screen program 603, this embodiment realizes the control of the secondary screen auxiliary information based on the main screen display content.

[0059] In the technical solution provided by the embodiment of the present application, during the main screen interaction process, by controlling the secondary screen 62 to display the auxiliary information corresponding to the main screen display content (i.e., the main page information), the control of the secondary screen auxiliary information based on the main screen display content is realized, reducing the difficulty of using the sequencer, improving the starting speed of the user independently using the sequencer for sequencing operations, and the use experience of the sequencer.

[0060] Figure 3 Another flowchart of the sequencer usage guidance method provided by the embodiment of the present application. In this embodiment, the step of determining the auxiliary information is refined based on the foregoing embodiment. As Figure 3 shown, the method includes: S310. Display the main page information of the sequencer on the main screen 61; S3101. In response to the trigger operation on the target control in the main screen 61, determine the main screen display content, the trigger object, and the action identifier; S3102. Control the trigger object to execute the action corresponding to the action identifier, and update the page status information corresponding to the main screen display content according to the main screen display content; S3103. Determine the auxiliary information corresponding to the updated page status information; and S320. Control the secondary screen 62 to display the auxiliary information.

[0061] The trigger object can be a component or a combination of multiple components. The action identifier is the identifier of the action to be executed by the trigger object. For example, if the trigger object is the main screen, the action identifier is 01 corresponding to the rise of the main screen; if the trigger object is the chamber door, the action identifier is 0001 corresponding to the opening of the chamber door.

[0062] In one embodiment, the same actions of different trigger objects are configured with different action identifiers. For example, for the chamber door labeled 1, the action identifier corresponding to the action of opening the chamber door is 0001; for the chamber door labeled 2, the action identifier corresponding to the action of opening the chamber door is 0010. By assigning different action identifiers to the same actions of different trigger objects, the flexibility and accuracy of using the action identifier can be improved.

[0063] Regarding the update of the page status information. Combining Figure 13BAs shown, in one embodiment, based on the main screen program 602 corresponding to the main screen 61, in response to a trigger operation on a target control in the main screen, the main screen display content (i.e., the main page information), the trigger object, and the action identifier are determined, the trigger object is controlled to perform an action corresponding to the action identifier, and the page state information corresponding to the main screen display content in the cache (i.e., the state buffer 605) is updated according to the main screen display content. In this embodiment, according to actual requirements, the main screen program 602 can control the trigger object to perform the action corresponding to the action identifier and update the page state information corresponding to the main screen display content in the cache simultaneously or sequentially.

[0064] Exemplarily, the user clicks "self-check" on the main screen. After the self-check is successful, a screen including "next step" is output. The user clicks the "next step" on the main screen 61. The main screen display content corresponding to this trigger operation is the consumable loading screen. The trigger object is the main screen 61, and the action identifier is 01 corresponding to the rising of the main screen 61. At this time, the processor controls the main screen to rise based on the main screen program 602, updates the page state information corresponding to the consumable loading screen in the cache according to the consumable loading screen, and controls the trigger object to perform the action corresponding to the action identifier; the processor determines the current auxiliary information based on the updated page state information in the cache based on the secondary screen program 603, and controls the secondary screen to display the auxiliary information. Since after the main screen 61 of the sequencer is lifted in place, the A-side chamber doors (the upper chamber door 65 and the lower chamber door 66 provided on the A side) are automatically unlocked and popped open, see Figure 4A . Therefore, the auxiliary information includes a schematic diagram of the main screen rising (see Figure 5 shown) and a chamber door opening prompt message (see Figure 6 shown). The chamber door opening reminder message includes a schematic diagram of the chamber door opening. The page state information can be selected as the software variable state information for the main screen picture. The secondary screen 62 in Figure 4A is provided below the main screen 61. In this exemplary embodiment, the trigger object performing the action corresponding to the action identifier and controlling the secondary screen to display the auxiliary information can be set to be synchronized or sequential to improve the guiding effect of the auxiliary information.

[0065] The technical solution provided by the embodiment of the present application determines the main screen display content corresponding to the trigger operation of the target control, controls the trigger object to perform the action corresponding to the action identifier, updates the page state information corresponding to the main screen display content according to the main screen display content, and controls the secondary screen 62 to display the auxiliary information corresponding to the updated page state information, realizing the association of the main screen display content, the action execution of the trigger object, and the auxiliary information, facilitating the user to comprehensively understand the current working process of the sequencer and reducing the operation difficulty of the sequencer.

[0066] Figure 7Another flowchart of the guiding method for using a sequencer provided by an embodiment of this application. In this embodiment, the step of determining auxiliary information is refined on the basis of the foregoing embodiment. As Figure 7 shown, the method includes: S400. Display the main page information of the sequencer on the main screen 61; S4101. Collect and detect the target status information set in real time. If the target status information set corresponds to a secondary screen trigger condition and the target status information set meets the secondary screen trigger condition, determine the auxiliary information corresponding to the target status information set. The target status information set includes component status information and / or page status information corresponding to the content displayed on the main screen; the auxiliary information includes at least one of sequencer status prompt information and operation guidance information, such as prompt information associated with the current sequencing node and / or prompt information corresponding to the next sequencing step.

[0067] In this embodiment, the detection module can obtain the parameter information collected by each parameter collection device in real time and synchronize the corresponding status information in the cache according to multiple parameter information. The processor 60 detects multiple status information in the cache in real time through the corresponding program to determine whether the target status information set meets the secondary screen trigger condition. For example, the secondary screen program detects multiple status information in the cache in real time to determine whether the target status information set meets the secondary screen trigger condition.

[0068] The cache in this embodiment mainly includes two types of status information, namely physical status information and virtual status information. The physical status information includes, but is not limited to, temperature status information, humidity status information, in-place status information for structures such as drawers, reagent trays, sample tubes, and chamber doors, and negative pressure status information, etc.; the virtual status information includes, but is not limited to, base recognition status information for indicating the status of the algorithm software; bioinformatics analysis status information for indicating the enabling and connection status of the bioinformatics analysis system; first variable status information for indicating the lifting status of the main screen; second variable status information for indicating the alarm status; page status information for indicating changes in the content displayed on the main screen. The temperature status information is determined based on the temperature data collected by the temperature sensor, the humidity status information is determined based on the humidity data collected by the humidity sensor, the in-place status information is determined based on the in-place signal collected by the in-place sensor, and the negative pressure status information is determined based on the negative pressure gauge.

[0069] Pre-configure at least one set of target status information, and each piece of target status information corresponds to an auxiliary information. Optionally, each piece of target status information is pre-set with a priority. When at least two pieces of target status information corresponding to different auxiliary information are detected simultaneously, control the secondary screen to display the corresponding auxiliary information based on this priority. For example, selectively display the auxiliary information corresponding to the target status information with a higher priority, or display different auxiliary information in sequence according to the priority order. During the use of the sequencer, the processor 60 determines at least one set of target status information to be confirmed according to a predetermined logic. For multiple pieces of target status information in the at least one set of target status information, real-time detect whether all the multiple pieces of target status information in the current set of target status information meet the corresponding secondary screen trigger conditions; if all the multiple pieces of target status information in the current set of target status information meet the corresponding secondary screen trigger conditions, then determine that the current set of target status information meets the secondary screen trigger conditions, and thus read the corresponding auxiliary information and control the secondary screen to display this auxiliary information.

[0070] Exemplarily, the set of target status information includes platform status information, which corresponds to only one secondary screen trigger condition. When the detection module detects that the reagent chamber door is opened, it generates the corresponding reagent chamber status information and synchronizes this reagent chamber status information to the cache (i.e., the status buffer 605 shown in Figure 13B ). Based on the secondary screen program 603 corresponding to the secondary screen 61, the processor 60 uses the set of target status information including the platform status information as the current set of target status information according to the predetermined on-board logic. If the reagent chamber status information read from the cache indicates that the reagent chamber is pulled out, determine the corresponding auxiliary information for this set of target status information. For example, as shown in Figure 8 the schematic diagram of kit placement and text prompt information, where the text prompt information includes "Place the sample and reagent, tear off the seal film of sequencing reagent slot 1, and pay attention to the notch direction. Remove the tube cap of the sample tube and place it in the corresponding hole according to the digital order direction. Remove the tube cap of the cryopreservation tube and place it in the corresponding hole according to the label color".

[0071] In one embodiment, the set of target status information includes action status information corresponding to the triggering object; when the action status information indicates that the triggering object moves in place, determine that the set of target status information meets the secondary screen trigger conditions.

[0072] Exemplarily, after detecting that the main screen 61 has been lifted to completion, the device control module generates main screen in-place information and updates the main screen action status information corresponding to the main screen in-place information in the cache. The secondary screen program determines the current set of target status information based on a predetermined logic, detects the main screen action status information in the set of target status information in the cache (status register 605), and determines that the set of target status information meets the secondary screen trigger condition and determines the auxiliary information corresponding to the set of target status information when the main screen action status information indicates that the main screen has moved into place.

[0073] As Figure 7 shown, the step of determining the auxiliary information in this embodiment further includes: S4102. If the set of target status information corresponds to at least two secondary screen trigger conditions and the set of target status information meets one of the at least two secondary screen trigger conditions, determine the auxiliary information corresponding to the set of target status information and the secondary screen trigger condition that the set of target status information currently meets; and S420. Control the secondary screen to display the auxiliary information.

[0074] At least two pieces of auxiliary information are pre-set for a specified set of target status information, and different pieces of auxiliary information correspond to different predetermined secondary screen trigger conditions. When the processor detects that the set of target status information meets any predetermined secondary screen trigger condition, it determines the set of target status information and the auxiliary information corresponding to the predetermined secondary screen trigger condition that the set of target status information currently meets, and controls the secondary screen to display the auxiliary information. In this embodiment, as the states of multiple components in the sequencer change and / or the pose of the chip sample changes, the auxiliary information displayed on the secondary screen also changes accordingly, so that the user can timely understand the current state or current sequencing progress of the sequencer through the auxiliary information displayed on the secondary screen.

[0075] Exemplarily, the set of target status information includes chip status information and encoding status information. When the chip status information indicates that the chip is placed in place and the encoding status information indicates that the encoding information of the chip sample is successfully obtained, it corresponds to the first secondary screen trigger condition; when the chip status information indicates that the chip is successfully placed and the encoding status information indicates that the encoding information of the chip sample is obtained unsuccessfully, it corresponds to the second secondary screen trigger condition; when the chip status information indicates that the chip is placed incorrectly and the encoding status information indicates that the encoding information of the chip sample is successfully obtained, it corresponds to the third secondary screen trigger condition; when the chip status information indicates that the chip is misplaced and the encoding status information indicates that the encoding information of the chip sample is obtained unsuccessfully, it corresponds to the fourth secondary screen trigger condition. When the detection module collects the chip in-place signal through the in-place sensor and scans the encoding information of the chip sample through the radio frequency identification structure, it synchronizes the corresponding chip status information in the cache according to the chip in-place signal and updates the encoding status information in the cache according to the encoding information. The processor determines the set of target status information based on the secondary screen program corresponding to the secondary screen and based on the pre-determined consumable loading logic. The set of target status information includes chip status information and encoding status information, and reads the chip status information and encoding status information from the cache. If the chip status information indicates that the chip is in place and the encoding status information indicates that the encoding of the chip sample is successfully obtained, it is determined that the set of target status information meets the first secondary screen trigger condition, and thus the auxiliary information corresponding to the set of target status information and the first secondary screen trigger condition is determined; if the chip status information indicates that the chip is in place and the encoding status information indicates that the encoding of the chip sample is obtained unsuccessfully, it is determined that the set of target status information meets the second secondary screen trigger condition, and thus the auxiliary information corresponding to the set of target status information and the second secondary screen trigger condition is determined; if the chip status information indicates that the chip is placed incorrectly and the encoding status information indicates that the encoding of the chip sample is successfully obtained, it is determined that the set of target status information meets the third secondary screen trigger condition, and thus the auxiliary information corresponding to the set of target status information and the third secondary screen trigger condition is determined; if the chip status information indicates that the chip is placed incorrectly and the encoding status information indicates that the encoding of the chip sample is obtained unsuccessfully, it is determined that the set of target status information meets the fourth secondary screen trigger condition, and thus the auxiliary information corresponding to the set of target status information and the fourth secondary screen trigger condition is determined. In this embodiment, the auxiliary information corresponding to different secondary screen trigger conditions is different. Taking the auxiliary information corresponding to the first secondary screen trigger condition as an example, it can be configured as the descending prompt information of the lifting screen where the main screen is located (see Figure 9 ) and the closing animation of the lifting screen.

[0076] In one embodiment, the set of target status information includes page status information and component status information. Combining Figure 10 and Figure 13BAs shown, the processor 60 generates page status information based on the touch screen click event and the mouse click event in the main screen 61 in response to the main screen program 602; the processor 60 controls the detection module (the input / output (I / O) interface set 642) to obtain component status information based on the touch screen click event and the mouse click event; the processor 60 calls the secondary screen program 603, determines the current target status information set based on a predetermined logic, reads multiple target status information in the target status information set from the cache to update the target status information set, and determines the auxiliary information corresponding to the updated target status information set, and controls the secondary screen 62 to display the auxiliary information.

[0077] In the technical solution provided by the embodiment of the present application, since multiple target status information in the target status information set can all reflect the status of the corresponding component, and the auxiliary information corresponds to the target status information set and the secondary screen trigger condition currently corresponding to the target status information set, the auxiliary information is adjusted in real time based on the component status information.

[0078] Figure 11A It is a schematic structural diagram of a sequencing instrument usage guiding device provided by an embodiment of the present application. As shown in FIG. 11, the device includes a main screen module 51, an auxiliary information module 52, and a display module 53.

[0079] The main screen module 51 is coupled to the main screen 61 to control the main screen 61 to display the main page information of the sequencing instrument.

[0080] The auxiliary information module 52 has an I / O acquisition unit (for example, Figure 13B the I / O interface set 642 shown) that collects and detects the target status information set in real time. When the I / O acquisition unit detects that the target status information set meets the secondary screen trigger condition, the auxiliary information module 52 determines the auxiliary information corresponding to the target status information set. The target status information set includes component status information and / or page status information corresponding to the main screen display content. The auxiliary information includes prompt information associated with the current sequencing node and / or prompt information corresponding to the next sequencing step; the display module 53 is coupled to the secondary screen 62 to control the secondary screen 62 to display the auxiliary information.

[0081] In one embodiment, the auxiliary information module 52 includes: a status information unit configured to determine the main screen display content in response to a trigger operation on a target control in the main screen, and update the page status information corresponding to the main screen display content according to the main screen display content; an auxiliary information module configured to determine the auxiliary information corresponding to the updated page status information when it detects that the page status information corresponding to the main screen display content is updated.

[0082] In one embodiment, the status information unit is configured to: in response to a triggering operation on a target control in the main screen 61, determine the main screen display content, the triggering object, and the action identifier; control the triggering object to execute an action corresponding to the action identifier, and update the page status information corresponding to the main screen display content according to the main screen display content.

[0083] In one embodiment, the status information unit is configured to: based on the main screen program corresponding to the main screen, in response to a triggering operation on a target control in the main screen, determine the main screen display content, update the page status information corresponding to the main screen display content according to the main screen display content, and control the main screen to display the main screen display content;

[0084] The auxiliary information module 52 is configured to: based on the secondary screen program corresponding to the secondary screen, determine the auxiliary information corresponding to the updated page status information when it detects that the page status information corresponding to the main screen display content is updated.

[0085] In one embodiment, the auxiliary information module 52 is configured to perform the following steps: if the target status information set corresponds to a secondary screen trigger condition and the target status information set meets the secondary screen trigger condition, determine the auxiliary information corresponding to the target status information set; if the target status information set corresponds to at least two secondary screen trigger conditions and the target status information set meets one of the at least two secondary screen trigger conditions, determine the auxiliary information corresponding to the target status information set and the secondary screen trigger condition that the target status information set currently meets.

[0086] In one embodiment, the target status information set includes the action status information corresponding to the triggering object; when the action status information indicates that the triggering object has moved in place, it is determined that the target status information set meets the secondary screen trigger condition.

[0087] In one embodiment, the auxiliary information is an animation segment or a target image, and the target image includes an icon and / or text information.

[0088] In one embodiment, as Figure 11B shown, the device further includes a set determination module 50, and the set determination module 50 is configured to: based on a predetermined logic and the component status information and / or page status information associated with the current interaction operation, determine the current target status information set, where the interaction operation is a software interaction operation or a hardware interaction operation.

[0089] The technical solution of the sequencing instrument use guiding device provided by the embodiments of the present application, due to at least one of the auxiliary information, the sequencing instrument status prompt information and the operation guiding information, therefore, by the way of displaying the auxiliary information associated with the set of sequencing instrument target status information on the secondary screen, and displaying the main page information of the sequencing instrument on the main screen, it not only separates the display screens where the auxiliary information and the main page information are located, but also enables the user to accurately lock the auxiliary information and quickly and accurately execute the operation content of the next step according to the auxiliary information. Therefore, the difficulty of using the sequencing instrument is greatly reduced, and the use experience of the sequencing instrument is improved.

[0090] The sequencing instrument use guiding device provided by the embodiments of the present application can execute the sequencing instrument use guiding method provided by any embodiment of the present application, and has function modules corresponding to the execution of the method.

[0091] Figure 12 It is a schematic structural diagram of a nucleic acid sequencing device provided by an embodiment of the present application. This embodiment and the foregoing embodiments belong to the same inventive concept. For the content not described in detail in this embodiment, please refer to the foregoing embodiments.

[0092] As Figure 12 、 Figure 13A - Figure 13C As shown, the nucleic acid sequencing device provided by the embodiments of the present application includes: a stage 70 configured to carry a sample to be detected; a fluid system 71 configured to provide various reagents for a detection reaction to the sample to be detected, and the sample to be detected reacts with the various reagents to generate a detectable signal; a detection system 72 configured to detect the detectable signal; a user guidance system including a main screen 61 and a secondary screen 62; and a processor 60 operably coupled to the user guidance system. The processor 60, based on the operation conditions of at least one of the stage 70, the fluid system 71, and the detection system 72, calls a main module (i.e., the main program 601) to control the operation of the nucleic acid sequencing device. During the operation of the main module, a first module (i.e., the main screen program 602) is called to control the main screen 61 to display main page information, and a second module (i.e., the secondary screen program 603) is called to control the secondary screen 62 to display auxiliary information. The first module (i.e., the main screen program 602) and the second module (i.e., the secondary screen program 603) are independent of each other.

[0093] The nucleic acid sequencing device provided by the embodiments of the present application includes a main screen 61 and a secondary screen 62. By displaying the main page information on the main screen 61 and displaying the auxiliary information on the secondary screen 62, it realizes the separation of the display screens used for the main page information and the auxiliary information, enabling the user to intuitively clarify the current device status or the next operation step prompt information of the nucleic acid sequencing device through the auxiliary information displayed on the secondary screen 62, which helps to reduce the difficulty of using the nucleic acid sequencing device for gene sequencing and improve the use experience of the nucleic acid sequencing device.

[0094] The stage 70 includes, for example, Figure 4A the chip platform 69 in [[ID=]], which is configured to carry the sample to be detected, for example, configured to carry the chip carrying the sample to be detected.

[0095] Figure 14 Inside the lower bin door 66 on side A and the lower bin door 68 on side B in [[ID=]], a fluid system 71 is provided, which is configured to provide various reagents for the detection reaction to the sample to be detected. Combining Figure 12 , in the embodiment of the present application, the stage 70 correspondingly supports two independent sequencing chips, and each single sequencing chip corresponds to an independent fluid system 71 respectively. The fluid system 71 is independently installed in the lower bin door 66 on side A and the lower bin door 68 on side B below both sides of the main screen 61 as described above.

[0096] The detection system 72 is configured to detect the detectable signal generated when the sample to be detected reacts with the above-mentioned various reagents, for example, including an image sensor for collecting fluorescence signals.

[0097] As Figure 13B shown, the processor 60 can be understood as a controller. The processor controls the operation of the nucleic acid sequencing device based on the preset logic of the main module (main program 601). During the operation of the main module, it will call the first module (main screen program 602) and / or the second module (secondary screen program 603) as needed. Among them, the first module is configured to control the main screen 61 to display the main page information of the nucleic acid sequencing device, and the second module can be configured to control the secondary screen 62 to display auxiliary information. The first module and the second module are independent, and they will not call each other during their operation.

[0098] The module can be understood as a software program. The main module is the main program of the nucleic acid sequencing device, the first module is the main screen program corresponding to the main screen, and the second module is the secondary screen program corresponding to the secondary screen.

[0099] When the second module (secondary screen program 603) runs, it can execute the following steps.

[0100] Step a1: When it is detected that the set of target status information meets the secondary screen trigger condition, determine the auxiliary information corresponding to the set of target status information. The set of target status information includes component status information and / or page status information corresponding to the display content of the main screen. The auxiliary information includes at least one of the sequencer status prompt information and the operation guidance information. The sequencer status prompt information is, for example, the working status information of the specified components (software and / or hardware) of the sequencer; the operation guidance information can be the guiding text, icon, and / or video provided for the user to operate the sequencer, for example, the prompt information corresponding to the next sequencing step.

[0101] Step a2, control the secondary screen 62 to display the auxiliary information.

[0102] The page state information is a software variable state information, which is associated with the main screen display content. Different main screen display contents correspond to different page state information.

[0103] The nucleic acid sequencing device includes hardware components and software components. The hardware components correspond to the hardware structure, and the software components correspond to software modules or software units. The component state information is used to reflect the current state of the component, such as the state of moving into place, whether the target information is missing, etc. The stage 70, the fluid system 71 and the detection system 72 are all hardware components.

[0104] For a nucleic acid sequencing device in a working state, the component state information of multiple components can be obtained on demand or in real time. In addition, whether the main screen display content changes, or even whether a target change occurs, can be reflected by the page state information. Therefore, through the target state information set including the page state information and / or the component state information, it is possible to judge the current operation node where the nucleic acid sequencing device is located or the current interaction content of the main screen, so as to control the secondary screen to display the auxiliary information corresponding to the operation node or the interaction content. This not only separates the display screens of the auxiliary information and the non-auxiliary information, but also enables the user to quickly and accurately lock the auxiliary information and perform the operation content of the next step quickly and accurately according to the auxiliary information, greatly reducing the difficulty of using the nucleic acid sequencing device.

[0105] Such as Figure 13B 、 Figure 13C As shown, in one embodiment, the nucleic acid sequencing device of the embodiment of the present application further includes an I / O interface set 642, and the I / O interface set 642 includes a first I / O interface 6422 coupled to the main screen. When the page state information corresponding to the main screen display content generated by the first I / O interface 6422 changes, the second module (i.e., the secondary screen program 603) controls the secondary screen 62 to display the auxiliary information corresponding to the updated page state information according to the page state information.

[0106] Such as Figure 13C As shown, the first I / O interface 6422 is configured to collect instructions for controlling the main screen 61, generate page state information corresponding to the main screen display content, and store the page state information in a cache (state buffer 605). When the second module (secondary screen program 603) detects from the cache that the page state information corresponding to the main screen display content generated by the first I / O interface 6422 changes, it updates the auxiliary information according to the page state information and controls the secondary screen 62 to display the updated auxiliary information. This embodiment updates the auxiliary information based on the page state information, ensuring the association between the auxiliary information and the main screen display content and improving the correctness of the auxiliary information.

[0107] Determination of page status information. In one embodiment, the main screen 61 has a target control for receiving a trigger operation. The first module (main screen program 602) determines the corresponding main screen display content in response to the trigger operation on the target control in the main screen, and updates the page status information corresponding to the main screen display content according to the main screen display content.

[0108] When the first module (main screen program 602) detects a trigger operation on the target control in the main screen 61 at the first I / O interface 6422, it determines the corresponding main screen display content of the trigger operation and controls the main screen to display the main screen display content; the first I / O interface 6422 updates the page status information corresponding to the display content of the main screen 61 in the status buffer 605 according to the change of the main screen display content. In this embodiment, the update of the page status information is completed by the first module (main screen program 602). Combined with the foregoing embodiment, that is, the combination of the first module (main screen program 602) and the second module (secondary screen program 603), the auxiliary information is updated in a timely manner based on the change of the main screen display content.

[0109] In one embodiment, the first module (main screen program 602) determines the main screen display content, the trigger object and the action identifier in response to the trigger operation on the target control in the main screen 61, and updates the page status information corresponding to the main screen display content according to the main screen display content; the main module (main program 601) controls the trigger object to execute the action corresponding to the action identifier.

[0110] On the basis of the foregoing embodiment, while the first module (main screen program 602) updates the page status information corresponding to the main screen display content according to the main screen display content, it sends the above trigger object and action identifier to the main module through the first I / O interface 6422; the main module (main program 601) controls the above trigger object to execute the action corresponding to the above action identifier. The combined use of the first module (main screen program 602) and the main module (main program 601) realizes the parallel or sequential progress of the movement of the hardware components and the update of the page status information.

[0111] In one embodiment, the device further includes a sensor 643 configured to detect the status information of any one of the system components of the stage 70, the fluid system 71, and the detection system 72 (see Figure 13C), and a second I / O interface 6423 associated with the sensor 643 to obtain the component status information collected by the sensor 643; when any of the component status information obtained by the second I / O interface 6423 changes, the second module (sub-screen program 603) controls the sub-screen 62 to display auxiliary information corresponding to the changed component status information. Exemplarily, the sensor 643 may be, for example, an infrared sensor installed on a nucleic acid sequencing device, and the infrared sensor interacts with the user's actions in real time to trigger the sub-screen to display auxiliary information corresponding to the user interaction, such as dynamic icons and other information.

[0112] The second I / O interface 6423 obtains the component status information collected by multiple sensors 643 in real time, and updates the corresponding status information in the cache according to the component status information corresponding to the multiple sensors 643. When the second module (sub-screen program 603) detects a change in the status information corresponding to multiple sensors in the status buffer 605, it determines the auxiliary information corresponding to the changed status information and controls the sub-screen 62 to display the auxiliary information. This embodiment realizes determining auxiliary information based on the component status information collected by the sensor.

[0113] In one embodiment, the I / O interface set 642 (see Figure 13B ) further includes a main I / O interface 6421 configured to obtain the main page information (see Figure 13C ); the second module (i.e., the sub-screen program 603) obtains the main page information determined by the main I / O interface 6421, and when the main page information changes, controls the sub-screen 62 to display the auxiliary information corresponding to the changed main page information. As Figure 13B and Figure 10 shown, a logic circuit 604 is further provided in the processor 60 to identify and process the above target status information set collected at the I / O interface set 642.

[0114] When the main module (main program 601) detects that the main page meets the corresponding predetermined conditions at the I / O interface set 642, it controls the main I / O interface to generate main page information and stores the main page information in the status buffer 605. When the status information corresponding to the main page information in the status buffer 605 changes, the second module (sub-screen program 603) determines the auxiliary information corresponding to the changed status information and controls the sub-screen 62 to display the auxiliary information.

[0115] In one embodiment, the target control corresponds to the main I / O interface 6421. In this way, once the target control is triggered, the main I / O interface 6421 can immediately detect the trigger operation; the first module (main program 601) responds to the trigger operation of the target control through the main I / O interface 6421, improving the response speed of the first module (main screen program 602) to the trigger operation of the target control.

[0116] In this embodiment, the main screen 61 and the secondary screen 62 are separately arranged. Through the mutually separated main screen 61 and secondary screen 62, the separation of the main page information and the auxiliary information is realized, and the separation of the main page information and the auxiliary information helps to improve the speed at which the user locks the auxiliary information and improve the guiding effect of the auxiliary information.

[0117] In one embodiment, if the target state information set corresponds to a secondary screen trigger condition and the target state information set meets the secondary screen trigger condition, the auxiliary information corresponding to the target state information set is determined; if the target state information set corresponds to at least two secondary screen trigger conditions and the target state information set meets one of the at least two secondary screen trigger conditions, the auxiliary information corresponding to the target state information set and the secondary screen trigger condition that the target state information set currently meets is determined.

[0118] For the display method of the nucleic acid sequencing device provided in the embodiments of the present application, please refer to Figure 1 . This embodiment and the foregoing embodiments belong to the same inventive concept. For the content not detailed in this embodiment, please refer to the foregoing embodiments.

[0119] As Figure 12 shown, the nucleic acid sequencing device in this embodiment has a structure similar to that of the sequencer in the above embodiment, including: a stage 70 configured to carry a sample to be detected; a fluid system 71 configured to provide various reagents for the detection reaction to the sample to be detected, and the sample to be detected reacts with the various reagents to generate a detectable signal; a detection system 72 configured to detect the detectable signal; a user guidance system including a main screen 61, a secondary screen 62, and a processor 60.

[0120] The display method of the nucleic acid sequencing device provided by the embodiment of the present application is configured to be executed by the processor 60, and includes: S110, displaying the main page information of the nucleic acid sequencing device on the main screen 61; S120, collecting and detecting a set of target status information, and determining auxiliary information corresponding to the set of target status information when it is detected that the set of target status information meets the sub-screen trigger condition; and S130, controlling the sub-screen 62 to display the auxiliary information. The auxiliary information includes at least one of sequencer status prompt information and operation guidance information. The sequencer status prompt information is, for example, the working status information of a specified component (software and / or hardware) of the sequencer; the operation guidance information may be guiding text, icons, and / or videos provided for the user to operate the sequencer, such as prompt information corresponding to the next sequencing step.

[0121] In the technical solution provided by the embodiment of the present application, since the auxiliary information includes at least one of sequencer status prompt information and operation guidance information, the display screen used to separate the main page information and the auxiliary information is realized by displaying the main page information on the main screen 61 and displaying the auxiliary information associated with the set of target status information of the nucleic acid sequencing device on the sub-screen 62. The user can intuitively clarify the current device status or operation step prompt information of the nucleic acid sequencing device through the auxiliary information displayed on the sub-screen 62, which helps to reduce the difficulty of using the nucleic acid sequencing device for gene sequencing and improve the use experience of the nucleic acid sequencing device.

[0122] Similarly, as Figure 13B and Figure 13C shown, in one embodiment, the processor 60 of the nucleic acid sequencing device includes an I / O interface set 642, a logic circuit 604 coupled to the I / O interface set 642, and a program module associated with the main screen 61 and the sub-screen 62. The program module includes a main program 601, a status buffer 605, a main screen program 602, and a sub-screen program 603. The main screen program 602 is associated with the main screen 61, and the sub-screen program 603 is associated with the sub-screen 62. The I / O interface set 642 includes a first I / O interface 6422 coupled to the main screen 61. The auxiliary information corresponding to the set of target status information is determined through the following steps: when the page status information corresponding to the main screen display content generated by the first I / O interface 6422 changes, the sub-screen program 603 controls the sub-screen 62 to display the auxiliary information corresponding to the updated page status information according to the page status information.

[0123] In one embodiment, the main screen 61 has a target control for receiving a trigger operation. The display method of the nucleic acid sequencing device of the present application determines the page state information through the following steps: in response to the trigger operation on the target control in the main screen 61, determine the corresponding main screen display content, and the first module (main screen program 602) updates the page state information corresponding to the main screen display content according to the main screen display content.

[0124] In one embodiment, the nucleic acid sequencing device further includes a sensor 643 configured to detect the state information of any one of the system components of the stage 70, the fluid system 71, and the detection system 72. Correspondingly, the I / O interface set 642 further includes a second I / O interface 6243 associated with the sensor 643 to obtain the component state information collected by the sensor 643. The display method of the nucleic acid sequencing device in this embodiment determines the auxiliary information through the following steps: when any of the component state information obtained by the second I / O interface changes, the second module (sub-screen program 603) controls the sub-screen 62 to display the auxiliary information corresponding to the changed component state information.

[0125] In one embodiment, the I / O interface set 642 further includes a main I / O interface 6421 configured to obtain the main page information. The auxiliary information is determined through the following steps: when the main page information determined by the main I / O interface 6421 changes, the second module (sub-screen program 603) controls the sub-screen 62 to display the auxiliary information corresponding to the changed main page information.

[0126] In one embodiment, if the set of target state information collected by the I / O interface set 642 corresponds to a sub-screen trigger condition and the set of target state information meets the sub-screen trigger condition, then determine the auxiliary information corresponding to the set of target state information; if the set of target state information corresponds to at least two sub-screen trigger conditions and the set of target state information meets one of the at least two sub-screen trigger conditions, then determine the auxiliary information corresponding to the set of target state information and the sub-screen trigger condition that the set of target state information currently meets.

[0127] Figure 13A It is a schematic structural diagram of the sequencer provided in the embodiment of the present application. This embodiment and the foregoing embodiments belong to the same inventive concept. For the content not detailed in this embodiment, please refer to the foregoing embodiments. As Figure 13AAs shown in the figure, the sequencer includes a main screen 61, a secondary screen 62, multiple components, at least two component status information determination units 631, a page status information determination unit 632, and a processor 60. The main screen 61 is configured to display the main screen display content; the secondary screen 62 is configured to output auxiliary information; the multiple components, some or all of the multiple sequencing-related components can be used in combination to complete the sequencing operations of multiple sequencing nodes in the sequencing process; at least two component status information determination units 631, the component status information determination unit is configured to determine the component status information of the corresponding component; the page status information determination unit 632 is configured to determine the page status information corresponding to the main screen display content; the processor 60 is configured to execute the sequencer usage guidance method described in any embodiment.

[0128] In the technical solution of the sequencer provided by the embodiment of the present application, since the auxiliary information includes at least one of the sequencer status prompt information and the operation guidance information, therefore, by the method of displaying the auxiliary information associated with the sequencer target status information set on the secondary screen 62, not only the separation of the auxiliary information and the non-auxiliary information on the display screen is completed, but also the user can accurately lock the auxiliary information and quickly and accurately execute the operation content of the next step according to the auxiliary information. Therefore, the usage difficulty of the sequencer is greatly reduced, and the usage experience of the sequencer is improved.

[0129] The component status information determination units for different components may be the same or different. However, the component status information determination unit can be set as one of a sensor, a radio frequency identification mechanism, or an I / O interface configured to detect the component moving in place.

[0130] The page status information determination unit can be configured as a software unit and can be called by the main screen program in the foregoing embodiment.

[0131] The sequencer in this embodiment includes a main screen 61, a secondary screen 62, and other structures. In this embodiment, the setting position of the secondary screen in the sequencer is not limited, nor is the implementation manner of the main screen and other structures limited.

[0132] Exemplarily, as Figure 14 and Figure 4A shown, the sequencer includes a front panel, which includes a main screen 61, a secondary screen 62 arranged below the main screen 61, an A-side upper chamber door 65 arranged on one side of the main screen, an A-side lower chamber door 66 arranged below the A-side upper chamber door 65, a B-side upper chamber door 67 arranged on the other side of the main screen, a B-side lower chamber door 68 arranged below the B-side upper chamber door 67, and a chip platform 69 arranged behind the main screen 61. Figure 4AAfter the main screen 61 is lifted, the chip platform 69 can be seen. Among them, the upper bin door 65 on side A and the upper bin door 67 on side B are respectively arranged on the left and right sides of the main screen 61, and the lower bin door 66 on side A and the lower bin door 68 on side B are respectively arranged on the lower left and right sides of the secondary screen 62. It can be understood that the sequencer also includes other structures such as a scanning mechanism (detection system 72) arranged inside the sequencer, which will not be elaborated in this embodiment. The sequencer includes an electronic device, and the processor 60 is arranged in the electronic device.

[0133] Figure 15 FIG. shows a schematic structural diagram of an electronic device 10 that can be used to implement the embodiments of the present application. The electronic device is intended to represent various forms of digital computers, such as laptop computers, desktop computers, workstations, personal digital assistants, servers, blade servers, mainframe computers, and other suitable computers. The components shown herein, their connections and relationships, and their functions are merely examples and are not intended to limit the implementation of the present application described and / or claimed herein.

[0134] As Figure 15 shown, the electronic device 10 includes at least one processor 11 (i.e., Figure 13B the processor 60 shown), and a memory communicatively connected to at least one processor 11, such as a read-only memory (ROM) 12, a random access memory (RAM) 13, etc. Among them, the memory stores a computer program executable by at least one processor. The processor 11 can perform various appropriate actions and processes according to the computer program stored in the read-only memory (ROM) 12 or the computer program loaded from the storage unit 18 into the random access memory (RAM) 13. In the RAM 13, various programs and data required for the operation of the electronic device 10 can also be stored. The processor 11, the ROM 12, and the RAM 13 are connected to each other through a bus 14. The input / output (I / O) interface 15 (i.e., the above-mentioned I / O interface set 642) is also connected to the bus 14.

[0135] Multiple components in the electronic device 10 are connected to the I / O interface 15, including: an input unit 16, such as a keyboard, a mouse, etc.; an output unit 17, such as various types of displays, speakers, etc. (including the main screen 61 and the secondary screen 62 in the above embodiments); a storage unit 18, such as a disk, an optical disc, etc.; and a communication unit 19, such as a network card, a modem, a wireless communication transceiver, etc. The communication unit 19 allows the electronic device 10 to exchange information / data with other devices through a computer network such as the Internet and / or various telecommunication networks.

[0136] The processor 11 can be various general-purpose and / or special-purpose processing components with processing and computing capabilities. Some examples of the processor 11 include, but are not limited to, a Central Processing Unit (CPU), a Graphics Processing Unit (GPU), various dedicated Artificial Intelligence (AI) computing chips, various processors running machine learning model algorithms, a Digital Signal Processor (DSP), and any suitable processor, controller, microcontroller, etc. The processor 11 executes the multiple methods and processes described above, such as the sequencing instrument using the guiding method or the display method of the nucleic acid sequencing device.

[0137] In some embodiments, the sequencing instrument using the guiding method or the display method of the nucleic acid sequencing device can be implemented as a computer program, which is tangibly included in a computer-readable storage medium, such as the storage unit 18. In some embodiments, part or all of the computer program can be loaded and / or installed onto the electronic device 10 via the ROM 12 and / or the communication unit 19. When the computer program is loaded into the RAM 13 and executed by the processor 11, one or more steps of the sequencing instrument using the guiding method or the display method of the nucleic acid sequencing device described above can be executed. Alternatively, in other embodiments, the processor 11 can be configured to execute the sequencing instrument using the guiding method or the display method of the nucleic acid sequencing device by any other suitable means (e.g., by means of firmware).

[0138] Various embodiments of the systems and techniques described above in this specification can be implemented in digital electronic circuitry, integrated circuit systems, field-programmable gate arrays (FPGAs), application specific integrated circuits (ASICs), application specific standard parts (ASSPs), system on chip (SOC) systems, complex programmable logic devices (CPLDs), computer hardware, firmware, software, and / or combinations thereof. These various embodiments can include: being implemented in one or more computer programs that are executable and / or interpretable on a programmable system including at least one programmable processor, which may be a special-purpose or general-purpose programmable processor that receives data and instructions from, and transmits data and instructions to, a storage system, at least one input device, and at least one output device.

[0139] The computer programs for implementing the methods of this application can be written in any combination of one or more programming languages. These computer programs can be provided to a processor of a general purpose computer, special purpose computer, or other programmable data processing apparatus, such that the computer programs, when executed by the processor, cause the functions / operations specified in the flowchart and / or block diagram to be implemented. The computer programs can be executed entirely on the machine, partly on the machine, as a stand-alone software package partly on the machine and partly on a remote machine or entirely on the remote machine or server.

[0140] In the context of this application, a computer-readable storage medium can be a tangible medium that can contain or store a computer program for use by or in connection with an instruction execution system, apparatus, or device. The computer-readable storage medium can include, but is not limited to, electronic, magnetic, optical, electromagnetic, infrared, or semiconductor systems, apparatus, or devices, or any suitable combination of the foregoing. Alternatively, the computer-readable storage medium can be a machine-readable signal medium. Examples of machine-readable storage media would include electrical connections based on one or more wires, a portable computer diskette, a hard disk, a random access memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM) or Flash memory, an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing.

[0141] To provide for interaction with a user, the systems and techniques described herein can be implemented on an electronic device having: a display device (e.g., a cathode ray tube (CRT) or a liquid crystal display (LCD) monitor) configured to display information to the user; and a keyboard and a pointing device (e.g., a mouse or a trackball) by which the user can provide input to the electronic device. Other kinds of devices can also be configured to provide for interaction with a user; for example, feedback provided to the user can be any form of sensory feedback (e.g., visual feedback, auditory feedback, or tactile feedback); and input from the user can be received in any form (including acoustic, speech, or tactile input).

[0142] The systems and techniques described herein can be implemented in a computing system including backend components (e.g., as a data server), or a computing system including middleware components (e.g., an application server), or a computing system including frontend components (e.g., a user computer having a graphical user interface or a web browser through which a user can interact with an implementation of the systems and techniques described herein), or a computing system including any combination of such backend components, middleware components, or frontend components. The components of the system can be interconnected to each other by digital data communication in any form or medium (e.g., a communication network). Examples of communication networks include: Local Area Network (LAN), Wide Area Network (WAN), blockchain network, and the Internet.

[0143] A computing system can include a client and a server. The client and the server are generally remote from each other and typically interact through a communication network. The client - server relationship is created by computer programs running on respective computers and having a client - server relationship with each other. The server can be a cloud server, also known as a cloud computing server or cloud host, which is a host product in the cloud computing service system, solving the defects of difficult management and weak business scalability existing in traditional physical hosts and Virtual Private Server (VPS) services.

[0144] An embodiment of the present application also provides a computer program product, including a computer program which, when executed by a processor, implements the sequencing instrument usage guiding method or the display method of a nucleic acid sequencing device provided in any embodiment of the present application.

[0145] In the process of implementing the computer program product, computer program code for performing the operations of the present application can be written in one or more programming languages or combinations thereof. The programming languages include object - oriented programming languages such as Java, Smalltalk, C++, and also include conventional procedural programming languages such as the "C" language or similar programming languages. The program code can be executed entirely on the user's computer, partially on the user's computer, executed as an independent software package, partially on the user's computer and partially on a remote computer, or entirely on a remote computer or server. In the case of a remote computer, the remote computer can be connected to the user's computer through any type of network - including a Local Area Network (LAN) or a Wide Area Network (WAN)—or can be connected to an external computer (e.g., by using an Internet service provider to connect through the Internet).

[0146] It should be understood that various forms of processes as shown above can be used, with steps reordered, added or deleted. For example, multiple steps recited in this application can be executed in parallel, sequentially or in different orders, as long as the desired results of the technical solution of this application can be achieved, and no limitation is made herein.

Claims

1. A method for guiding the use of a sequencer, wherein the sequencer comprises a main screen and a secondary screen, comprising: Displaying the main page information of the sequencer on the main screen; Collect and detect a target state information set in real time, and when it is detected that the target state information set meets the secondary screen triggering condition, determine auxiliary information corresponding to the target state information set, wherein the target state information set includes at least one of component state information and page state information corresponding to the main screen display content, and the auxiliary information is different from the main page information displayed on the main screen; Controlling the secondary screen to display the auxiliary information; The auxiliary information includes at least one of the following displayed on the secondary screen: sequencer status prompt information and operation guide information; The sequencer status prompt information is configured to present the working status of designated components of the sequencer; the operation guidance information includes at least one of text, icons and videos providing guidance for the user to operate the sequencer.

2. The method according to claim 1, wherein: The determining of auxiliary information corresponding to the target state information set when it is detected that the target state information set meets the secondary screen triggering condition includes: In response to a triggering operation on a target control in the main screen, determining the main screen display content, and updating page status information corresponding to the main screen display content according to the main screen display content; When it is detected that the page status information corresponding to the main screen display content is updated, the auxiliary information corresponding to the updated page status information is determined.

3. The method according to claim 2, wherein: The determining the main screen display content in response to the triggering operation on the target control in the main screen, and updating the page status information corresponding to the main screen display content according to the main screen display content, includes: In response to a trigger operation on a target control in the main screen, determining main screen display content, a trigger object, and an action identifier; The trigger object is controlled to execute an action corresponding to the action identifier, and page status information corresponding to the main screen display content is updated according to the main screen display content.

4. The method according to claim 2, wherein: The determining the main screen display content in response to the triggering operation on the target control in the main screen, and updating the page status information corresponding to the main screen display content according to the main screen display content, includes: Based on a main screen program corresponding to the main screen, in response to a trigger operation on a target control in the main screen, determining main screen display content, updating page status information corresponding to the main screen display content according to the main screen display content, and controlling the main screen to display the main screen display content; The step of determining the auxiliary information corresponding to the updated page status information when detecting that the page status information corresponding to the main screen display content is updated includes: Based on the secondary screen program corresponding to the secondary screen, when it is detected that the page status information corresponding to the main screen display content is updated, the auxiliary information corresponding to the updated page status information is determined.

5. The method according to claim 1, wherein: The determining, when detecting that the target state information set meets the secondary screen triggering condition, the auxiliary information corresponding to the target state information set includes: In response to the target state information set corresponding to a secondary screen trigger condition, and the target state information set meets the secondary screen trigger condition, determining the auxiliary information corresponding to the target state information set; In response to the target state information set corresponding to at least two secondary screen trigger conditions, and the target state information set meets one of the at least two secondary screen trigger conditions, the auxiliary information corresponding to the target state information set and the secondary screen trigger condition currently met by the target state information set is determined.

6. The method according to claim 5, wherein: The target state information set includes action state information corresponding to the trigger object; When the action state information indicates that the trigger object has moved into position, it is determined that the target state information set meets the first secondary screen triggering condition.

7. The method according to claim 1, wherein: The auxiliary information is a cartoon clip or a target image, and the target image includes at least one of an icon and text information.

8. The method according to claim 1, wherein before determining the auxiliary information corresponding to the target state information set when it is detected that the target state information set meets the secondary screen triggering condition, the method further comprises: A current target state information set is determined based on a predetermined logic and at least one of component state information and page state information associated with a current interactive operation, wherein the interactive operation is a software interactive operation or a hardware interactive operation.

9. A sequencer use guide device, the sequencer comprising a main screen and a secondary screen, the device comprising a main screen module, an auxiliary information module and a display module; The main screen module is coupled to the main screen to control the main screen to display the main page information of the sequencer; The auxiliary information module has an input / output I / O acquisition unit for real-time acquisition and detection of a target state information set; when the I / O acquisition unit detects that the target state information set meets the secondary screen triggering condition, the auxiliary information module determines the auxiliary information corresponding to the target state information set, the target state information set includes at least one of component state information and page state information corresponding to the main screen display content, and the auxiliary information is different from the main page information displayed on the main screen; The display module is coupled to the secondary screen to control the secondary screen to display the auxiliary information.

10. The sequencer use guide device as claimed in claim 9, wherein: The auxiliary information includes at least one of the following displayed on the secondary screen: sequencer status prompt information and operation guide information; the sequencer status prompt information is configured to present the working status of specified components of the sequencer; the operation guide information includes at least one of text, icons and videos providing guidance for users to operate the sequencer.

11. The sequencer use guide device as claimed in claim 10, wherein: The sequencer status prompt information includes at least one of the following: equipment monitoring information that reflects the specified performance parameters and operating indicators of the sequencer in real time; update and maintenance information that prompts the software update status, maintenance requirements and maintenance progress of the sequencer.

12. A nucleic acid sequencing device, comprising: A carrier, the carrier being configured to carry a sample to be detected; A fluid system, wherein the fluid system is configured to provide a plurality of reagents for a detection reaction to the sample to be detected, and the sample to be detected reacts with the plurality of reagents to generate a detectable signal; a detection system configured to detect the detectable signal; as well as User guidance system, including main screen and secondary screen; as well as A processor is operably coupled to the user guidance system, and the processor calls a main module to control the operation of the nucleic acid sequencing device based on the operation status of at least one of the carrier, the fluid system, and the detection system. During the operation of the main module, the first module is called to control the main screen to display the main page information, and the second module is called to control the sub-screen to display auxiliary information different from the main page information. The first module and the second module are independent of each other.

13. The nucleic acid sequencing device according to claim 12, wherein: When the second module is called by the processor, the following steps are performed: In the case where it is detected that the target state information set meets the secondary screen triggering condition, auxiliary information corresponding to the target state information set is determined, the target state information set includes at least one of component state information and page state information corresponding to the main screen display content, and the auxiliary information includes at least one of sequencer state prompt information and operation guide information; the sequencer state prompt information is configured to present the working state of a specified component of the sequencer; the operation guide information includes at least one of a text, an icon and a video providing guidance for a user to operate the sequencer; Control the secondary screen to display the auxiliary information.

14. The nucleic acid sequencing device according to claim 13, further comprising an input / output I / O interface set, wherein the I / O interface set comprises a first I / O interface coupled to the main screen; When the page status information corresponding to the main screen display content generated by the first I / O interface changes, the second module controls the secondary screen to display the auxiliary information corresponding to the updated page status information according to the page status information.

15. The nucleic acid sequencing device according to claim 14, wherein: The main screen has a target control for receiving a trigger operation, the first module determines the corresponding main screen display content in response to the trigger operation on the target control in the main screen, and updates the page status information corresponding to the main screen display content according to the main screen display content.

16. The nucleic acid sequencing apparatus according to claim 14, further comprising a sensor configured to detect status information of any system component in the carrier, the fluid system, and the detection system, and a second I / O interface associated with the sensor to obtain component status information collected by the sensor; When any of the component status information acquired by the second I / O interface changes, the second module controls the secondary screen to display the auxiliary information corresponding to the changed component status information.

17. The nucleic acid sequencing device according to claim 15, wherein: The I / O interface set also includes a main I / O interface configured to obtain the main page information; The second module obtains the main page information determined by the main I / O interface, and controls the secondary screen to display the auxiliary information corresponding to the changed main page information when the main page information changes.

18. The nucleic acid sequencing device according to claim 17, wherein: The target control corresponds to the main I / O interface.

19. The nucleic acid sequencing device according to claim 12, wherein: The main screen and the sub-screen are arranged separately from each other.

20. The nucleic acid sequencing device according to claim 15, wherein: The first module determines the main screen display content, the trigger object and the action identifier in response to the trigger operation on the target control in the main screen, and updates the page status information corresponding to the main screen display content according to the main screen display content; The main module controls the trigger object to execute an action corresponding to the action identifier.

21. The nucleic acid sequencing device according to claim 13, wherein: In response to the target state information set corresponding to a secondary screen trigger condition, and the target state information set meets the secondary screen trigger condition, determining the auxiliary information corresponding to the target state information set; In response to the target state information set corresponding to at least two secondary screen trigger conditions, and the target state information set meets one of the at least two secondary screen trigger conditions, the auxiliary information corresponding to the target state information set and the secondary screen trigger condition currently met by the target state information set is determined.

22. A display method for a nucleic acid sequencing device, comprising: A carrier, the carrier being configured to carry a sample to be detected; A fluid system, wherein the fluid system is configured to provide a plurality of reagents for a detection reaction to the sample to be detected, wherein the sample to be detected undergoes the detection reaction with the plurality of reagents and generates a detectable signal; and a detection system, wherein the detection system is configured to detect the detectable signal; A user guidance system, the user guidance system comprising a main screen and a secondary screen, and a processor, the display method being configured to be executed by the processor, comprising: Displaying the main page information of the nucleic acid sequencing device on the main screen; Collecting and detecting a target state information set, and when detecting that the target state information set meets the secondary screen triggering condition, determining auxiliary information corresponding to the target state information set and different from the main page information, the auxiliary information including at least one of sequencer state prompt information and operation guide information; the sequencer state prompt information is configured to present the working state of a specified component of the sequencer; the operation guide information includes at least one of a guide text, an icon, and a video for providing a user with instructions for operating the sequencer; Control the secondary screen to display the auxiliary information.

23. The display method of a nucleic acid sequencing device according to claim 22, wherein: The device also includes an input / output I / O interface set, the I / O interface set including a first I / O interface coupled to the main screen; The determining, when detecting that the target state information set meets the secondary screen triggering condition, the auxiliary information corresponding to the target state information set includes: Based on the second module, when the page status information corresponding to the main screen display content generated by the first I / O interface changes, the secondary screen is controlled to display the auxiliary information corresponding to the updated page status information according to the page status information.

24. The display method of a nucleic acid sequencing device according to claim 23, wherein: The main screen has a target control that receives a trigger operation; The determining the page status information includes: Based on the first module, corresponding main screen display content is determined in response to the trigger operation on the target control in the main screen, and the page status information corresponding to the main screen display content is updated according to the main screen display content.

25. The display method of a nucleic acid sequencing device according to claim 22, wherein: The device also includes a sensor configured to detect status information of any system component in the carrier, the fluid system, and the detection system, and a second I / O interface configured to obtain component status information collected by the sensor; The determining, when detecting that the target state information set meets the secondary screen triggering condition, the auxiliary information corresponding to the target state information set includes: Based on the second module, when any of the component status information acquired by the second I / O interface changes, the secondary screen is controlled to display the auxiliary information corresponding to the changed component status information.

26. The display method of a nucleic acid sequencing device according to claim 23, wherein: The I / O interface set also includes a main I / O interface configured to obtain the main page information; when it is detected that the target state information set meets the secondary screen trigger condition, determining the auxiliary information corresponding to the target state information set includes: Based on the second module, when the main page information determined by the main I / O interface changes, the secondary screen is controlled to display the auxiliary information corresponding to the changed main page information.

27. The display method of a nucleic acid sequencing device according to claim 22, wherein: The determining, when detecting that the target state information set meets the secondary screen triggering condition, the auxiliary information corresponding to the target state information set includes: In response to the target state information set corresponding to a secondary screen trigger condition, and the target state information set meets the secondary screen trigger condition, determining the auxiliary information corresponding to the target state information set; In response to the target state information set corresponding to at least two secondary screen trigger conditions, and the target state information set meets one of the at least two secondary screen trigger conditions, the auxiliary information corresponding to the target state information set and the secondary screen trigger condition currently met by the target state information set is determined.

28. A sequencer comprising: A main screen, configured to display main screen display content; A secondary screen is configured to output auxiliary information; A plurality of components, some or all of which can be used together to complete sequencing operations of a plurality of sequencing nodes in a sequencing process; at least two component state information determining units, the component state information determining units being configured to determine component state information of corresponding components; a page status information determining unit, configured to determine page status information corresponding to the main screen display content; A processor is configured to execute the sequencer usage guidance method described in any one of claims 1 to 8 or the display method of the nucleic acid sequencing device described in any one of claims 22 to 27.

29. A computer-readable storage medium storing computer instructions, wherein the computer instructions are used to enable a processor to implement the sequencer usage guidance method described in any one of claims 1 to 8 or the nucleic acid sequencing device display method described in any one of claims 22 to 27 when executed.

30. A computer program product, comprising a computer program, wherein when the computer program is executed by a processor, the computer program implements the sequencer usage guidance method according to any one of claims 1 to 8 or the display method of the nucleic acid sequencing device according to any one of claims 22 to 27.

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