A disintegration time endpoint automatic sensing system, method and device
By combining photoelectric sensors and motion state sensors, the problems of high cost and large measurement errors in existing disintegration endpoint detection devices are solved, and automatic timing and accurate measurement of the drug disintegration time endpoint are achieved, reducing manufacturing costs and improving reliability.
Patent Information
- Application Number
- CN202510281870.9
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- Filing Date
- 2025-03-11
- Publication Date
- 2025-09-12
- Estimated Expiration
- 2045-03-11
AI Technical Summary
Existing automatic disintegration endpoint detection devices have problems such as high R&D costs, large measurement errors and poor applicability, especially the complex design of the induction screen and inaccurate measurement.
The design combines a photoelectric sensor with a motion state sensor, uses a conical mesh cover and a photoelectric sensor to detect the end point of drug disintegration, automatically times the time through the change of the light signal from the photoelectric sensor, and combines the motion state sensor to ensure measurement accuracy.
The automatic timing of the drug disintegration time endpoint is realized, which reduces manufacturing costs, improves measurement reliability and accuracy, and reduces manual intervention.
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Figure CN120084959B_ABST
Abstract
Description
Technical Field
[0001] The present invention relates to the technical field of automatic disintegration time limit sensing, and in particular to a system, method and device for automatic sensing of a disintegration time limit endpoint. Background Art
[0002] Disintegration refers to the complete disintegration, dissolution, or fragmentation of a solid dosage form within the inspection time limit. Except for insoluble coating materials or broken capsule shells, the solid dosage form should pass through a sieve. Disintegration time is determined using a lift-type disintegrator. Standard tablets should completely disintegrate within 15 minutes, hard capsules within 30 minutes, and soft capsules within one hour. Confirmation of disintegration time is typically done visually, which is subject to subjective error and consumes labor time.
[0003] In the prior art, there are automatic detection devices for the disintegration endpoint, such as the Chinese utility model patent with announcement number CN215493284U, which discloses a device for accurately determining the disintegration time endpoint of a preparation. The principle is to determine whether the drug has dissolved based on the pressure between the drug and the screen during the upward movement. Its main technical feature is the induction screen. This technical solution has the following problems in practice: on the one hand, the induction screen suitable for the disintegration instrument is not a standard induction device, and no specific manufacturer is investing in its production. Therefore, during the research and development process, the induction device needs to be designed from scratch, which is costly. On the other hand, during the upward movement, the solution above the screen will exert a certain amount of pressure on the screen. Since the drug to be disintegrated is itself light in weight, it will lead to large measurement errors. Summary of the Invention
[0004] To overcome the above-mentioned deficiencies of the prior art, the present invention provides an automatic sensing device for disintegration endpoint, which can automatically time the disintegration endpoint of the drug to be tested, saving manpower. Compared with the existing technical solutions for automatic detection devices for disintegration endpoint, the present invention has the advantages of low manufacturing cost, simple control principle and good reliability.
[0005] In order to achieve the above object, the present invention is implemented through the following technical solutions:
[0006] An automatic disintegration endpoint sensing device, comprising:
[0007] The disintegration instrument body includes a hanging basket and a lifting drive device that drives the hanging basket to move up and down;
[0008] The pipe body is installed on the hanging basket, and a conical mesh cover is provided at the bottom of the pipe body, and the diameter of the upper end of the conical mesh cover is larger than the diameter of the lower end;
[0009] The photoelectric sensor includes a transmitter and a receiver. The transmitter is installed below the conical mesh cover with its transmitting port facing the bottom opening of the conical mesh cover. When the drug sinks to the bottom of the conical mesh cover before complete disintegration, it can block the light signal emitted by the transmitter. The receiver is installed above the conical mesh cover with its receiving port facing the transmitting port of the transmitter.
[0010] The motion state sensor is used to detect whether the motion state of the hanging basket is in the preset ascending stroke.
[0011] Optionally, in the present application, an automatic sensing device for the end point of disintegration time limit, a lifting drive device includes a rotating transmission member and a linear moving component, the rotating transmission member is connected to the linear moving component, the linear moving component is connected to the hanging basket, and an induction magnet is provided on the rotating transmission member; the motion state sensor includes a Hall sensor, and the Hall sensor is arranged on one side of the induction magnet. When the rotating transmission member drives the induction magnet to rotate to the position corresponding to the Hall sensor, the linear moving component drives the hanging basket to be in a preset ascending stroke.
[0012] Optionally, in the present application, a disintegration time endpoint automatic sensing device, the motion state sensor includes an acceleration sensor, and when the acceleration sensor receives a signal of upward accelerated motion, it determines that the hanging basket is in a preset ascending stroke.
[0013] Furthermore, an automatic sensing device for the end point of disintegration time limit in the present application also includes a transmitter mounting bracket, which is installed at the lower end of the tube body and is connected to the tube body. The transmitter mounting bracket includes a base, and a mounting countersunk hole is provided at the bottom of the base. The transmitter transmitting end is arranged in the mounting countersunk hole, and a light-transmitting through hole is passed through the top of the mounting countersunk hole, and the light-transmitting through hole corresponds to the transmitting port of the transmitter.
[0014] Furthermore, in the present application, an automatic sensing device for disintegration time limit endpoint is provided, wherein the hanging basket includes an upper limit plate and a lower limit plate, wherein the upper limit plate is provided at the upper end of a group of tubes, and a group of tubes is passed through the lower limit plate, and the upper limit plate and the lower limit plate are provided with limit holes adapted to the tubes;
[0015] It also includes a connecting rod, which passes through the upper limit plate and the lower limit plate. A group of positioning nuts are sleeved on the outer wall of the connecting rod. The positioning nuts realize the axial positioning of the upper limit plate and the lower limit plate relative to the connecting rod. The upper end of the connecting rod is connected to the lifting drive device.
[0016] Furthermore, in the automatic sensing device for the end point of disintegration time in the present application, the connecting rod is a hollow tube with openings at both ends, and the lower end of the connecting rod extends to correspond to the emitter.
[0017] An automatic disintegration endpoint sensing system, comprising:
[0018] The lifting drive module is used to control the lifting drive device to drive the hanging basket to move up and down;
[0019] The motion state sensing module is used to detect that the hanging basket is in a preset ascending stroke to activate the photoelectric sensor;
[0020] Disintegration completion confirmation module, after the photoelectric sensor is activated, it detects whether the drug has completed disintegration;
[0021] Timing module, used to measure the time from the start to the completion of disintegration.
[0022] A method for automatically sensing the end point of disintegration time, based on an automatic sensing device for the end point of disintegration time, comprises the following steps:
[0023] The medicine is loaded into the tube of the hanging basket and placed between the conical mesh cover and the receiver;
[0024] The tube body is immersed in the solution and the lifting driving device drives the hanging basket to move up and down reciprocatingly;
[0025] The photoelectric sensor is activated when the hanging basket is detected to be in the preset upward stroke;
[0026] When the receiver receives the light signal sent by the transmitter, it is determined that the drug has completed disintegration.
[0027] It can be seen from the above technical solution that the present invention has the following beneficial effects:
[0028] The present application provides a disintegration time limit end point automatic sensing device, the principle of which is: the medicine placed in the tube body sinks to the bottom of the tube body, and due to the setting of the conical screen cover, the medicine will automatically occupy the center position of the conical screen cover due to gravity, and at this time it just blocks the launch port of the transmitter. When the disintegration experiment is carried out, when the hanging basket moves upward, the medicine will fit with the conical screen cover, and at this time it can be ensured that the undisintegrated medicine blocks the launch port of the transmitter, so that the receiver cannot detect the light signal emitted by the transmitter; when the medicine completes disintegration, at this time, there is no obstruction between the transmitter and the receiver, and the receiver can receive the light signal, thereby starting to stop timing, outputting timing data, and obtaining the disintegration time limit end point time. Therefore, the disintegration time limit end point automatic sensing device described in the present invention can realize automatic timing of the disintegration time limit end point of the drug to be tested, save manpower, and has the advantages of low manufacturing cost, simple control principle, and good reliability compared with the existing technical solutions for automatic detection devices for disintegration end points. BRIEF DESCRIPTION OF THE DRAWINGS
[0029] Figure 1 This is a schematic diagram of the three-dimensional structure of an automatic sensing device for disintegration time endpoint in one embodiment of the present application;
[0030] Figure 2 is a structural schematic diagram of the lifting drive device;
[0031] Figure 3 This is a schematic diagram of the installation of a Hall sensor and a sensing magnetic block in an automatic sensing device for disintegration time endpoint in one embodiment of the present application;
[0032] Figure 4 is a schematic diagram of the three-dimensional structure of the hanging basket;
[0033] Figure 5 An exploded view of the components of the hanging basket;
[0034] Figure 6 is a cross-sectional view of the hanging basket;
[0035] Figure 7 for Figure 6 A partial enlarged view of area A in the middle circle.
[0036] In the picture:
[0037] 1- Disintegration Apparatus Body; 11- Water Bath; 12- Lifting Drive; 121- Rotating Transmission; 122- Linear Motion Assembly; 123- Inductive Magnetic Block; 124- Lifting Rod; 125- Extension Plate; 126- Hanging Rod; 13- Hall Effect Sensor;
[0038] 2-basket; 21-tube body; 22-conical screen cover; 221-conical bottom; 222-annular sleeve; 23-upper limit plate; 24-lower limit plate; 25-connecting rod; 251-positioning nut; 252-wire trough; 253-limiting cap; 254-mounting plate; 255-wire through hole; 26-support plate;
[0039] 3-beaker;
[0040] 4-photoelectric sensor; 41-transmitter; 42-receiver; 421-floating head; 422-missing part;
[0041] 5-emitter mounting frame; 51-base; 511-mounting countersunk hole; 512-light-transmitting through hole; 513-conical fitting surface; 5134-limiting platform; 52-ring; 53-connecting plate. DETAILED DESCRIPTION
[0042] Example
[0043] Combine Figures 1 to 5The disintegration time limit endpoint automatic sensing device shown in the figure includes a disintegration instrument body 1, the disintegration instrument body 1 includes a water bath 11 and a lifting drive device 12, and also includes a beaker 3 and a hanging basket 2, the beaker 3 is arranged in the water bath 11, the hanging basket 2 is arranged in the beaker 3, and the lifting drive device 12 can drive the hanging basket 2 to reciprocate up and down in the beaker 3; a group of tubes 21 are provided in the hanging basket 2, and a conical screen cover 22 is provided at the bottom of the tube 21. The upper and lower ends of the conical screen cover 22 are open, and the upper end diameter of the conical screen cover 22 is larger than the lower end diameter; it also includes a photoelectric sensor 4, the photoelectric sensor 4 includes a transmitter 41 and a receiver 42, the transmitter 41 is arranged below the conical screen cover 22, the transmitting port of the transmitter 41 corresponds to the center position of the conical screen cover 22, the receiver 42 is arranged above the conical screen cover 22, and the receiving port of the receiver 42 corresponds to the transmitting port of the transmitter 41, and the transmitter 41 and the receiver 42 are electrically connected to the disintegration instrument control system;
[0044] The motion state sensor is used to detect whether the motion state of the hanging basket 2 is in a preset ascending stroke.
[0045] In this embodiment, the lifting drive device 12 includes a rotating transmission member 121 and a linear moving component 122. The rotating transmission member 121 is connected to the linear moving component 122 in transmission mode. The linear moving component 122 is connected to the hanging basket 2. The rotating transmission member 121 is provided with an induction magnetic block 123. Correspondingly, the motion state sensor includes a Hall sensor 13. The Hall sensor 13 is arranged on one side of the induction magnetic block 123. The Hall sensor 13 is electrically connected to the disintegration instrument control system. When the rotating transmission member 121 drives the induction magnetic block 123 to rotate to the position corresponding to the Hall sensor 13, the linear moving component 122 is in an upward movement stroke.
[0046] Specifically, the conical screen cover 22 is in the shape of a trumpet-shaped cover cylinder. In this embodiment, the number of the tube bodies 21 is 6, which are evenly spaced in the circumferential direction.
[0047] A method for using the automatic disintegration endpoint sensing device of this embodiment includes the following steps:
[0048] S1: Preparation: put the solution into the water bath 11 and the beaker 3, immerse the hanging basket 2 in the beaker 3, and connect the lifting drive device 12 to the hanging basket 2;
[0049] S2: To begin, the pill to be tested is placed in the tube body 21, the disintegration instrument is started, and the lifting drive device 12 drives the hanging basket 2 to move up and down in the beaker 3. The counting module of the disintegration instrument control system simultaneously performs timing. In order to prevent the drug from moving up and down for too long, a limit cover (not shown) that can be sunk into the solution in the immersion chamber can be provided to cover the drug. The limit cover is provided with a through hole that is positioned opposite to the emitter 41. The size of the through hole is the same as the mesh size of the conical screen cover 22.
[0050] S3: Emitting a light signal. When the hanging basket 2 moves upward, the induction magnetic block 123 rotates to a position corresponding to the Hall sensor 13. At this time, the Hall sensor 13 outputs a signal to the controller, and the controller controls the emitter 41 to emit a light signal.
[0051] S4: End point timing. After the pill has completely disintegrated and there is no obstruction between receiver 42 and transmitter 41, receiver 42 receives the light signal from transmitter 41, and the corresponding counter stops timing and outputs the timing data. The output destination for the timing data includes, but is not limited to, a display screen, a computer, or a printer.
[0052] In this embodiment, the rotating transmission member 121 rotates one circle, the linear moving component 122 completes one lifting, the induction magnetic block 123 is set on the rotating transmission member 121, and the Hall sensor 13 is fixed at a preset position. Since the rotation stroke position of the rotating transmission member 121 and the moving position (including direction parameters) of the linear moving component 122 can correspond one to one, the Hall sensor 13 can be used to detect whether the rotating transmission member 121 rotates to the preset position to determine whether the hanging basket 2 is in an upward moving state. The rotating transmission member 121 can be a cam or a crank, and the cam follower mechanism or the crank slider mechanism is used to achieve the above functions. In this embodiment, the rotating transmission member 121 is an eccentric wheel, and the lower end of the linear moving component 122 is in contact with the upper end of the eccentric wheel.
[0053] In other embodiments, the motion state sensor includes an acceleration sensor (not shown) installed on the hanging basket 2. When the acceleration sensor receives a signal of upward acceleration, it determines that the hanging basket 2 is in a preset ascending stroke.
[0054] The present embodiment of an automatic disintegration time limit end point sensing device has the following principle: the pill placed in the tube body 21 sinks to the bottom of the tube body 21. Due to the provision of the conical screen cover 22, the pill automatically settles to the center of the conical screen cover 22 due to gravity, thus blocking the launch port of the transmitter 41. During the disintegration experiment, when the hanging basket 2 moves upward, the pill will fit with the conical screen cover 22, ensuring that the undisintegrated pill blocks the launch port of the transmitter 41, thereby preventing the receiver 42 from detecting the light signal emitted by the transmitter 41. When the pill has completed disintegration, there is no obstruction between the transmitter 41 and the receiver 42, and the receiver 42 can receive the light signal, thereby starting to stop timing, outputting timing data, and obtaining the disintegration time limit end point time. It should be noted that the up and down movement frequency of the hanging basket 2 specified in the Pharmacopoeia is 30 to 32 times per minute. Therefore, the theoretical error of the disintegration time limit timing of the present embodiment of an automatic disintegration time limit sensing device is 1 second. Therefore, the automatic disintegration endpoint sensing device of this embodiment can automatically time the disintegration endpoint of the drug being tested, saving manpower. Compared with existing technical solutions for automatic detection of the disintegration endpoint, it has the advantages of low manufacturing cost, simple control principle, and good reliability. Among them, the photoelectric sensor 4 is preferably an underwater infrared photoelectric sensor.
[0055] Combine Figures 5 to 7 As shown, in this embodiment, a transmitter mounting frame 5 is also included. The transmitter mounting frame 5 is installed at the lower end of the tube body 21. The transmitter mounting frame 5 is connected to the tube body 21. The transmitter mounting frame 5 includes a base 51. A mounting countersunk hole 511 is provided at the bottom of the base 51. The transmitting end of the transmitter 41 is arranged in the mounting countersunk hole 511. A light-transmitting perforation 512 is provided at the top of the mounting countersunk hole 511. The light-transmitting perforation 512 corresponds to the transmitting port of the transmitter 41. The aperture of the light-transmitting perforation 512 is smaller than the sieve hole of the conical screen cover 22. The aperture size of the sieve hole of the disintegration instrument is the size specified in the "Pharmacopoeia", such as 2mm. When the particles after the disintegration of the pill are smaller than the sieve hole of the conical screen cover 22, the disintegration is considered to be complete. Therefore, the light-transmitting perforation 512 is smaller than the sieve hole of the conical screen cover 22, which can ensure that the pills that have not completed disintegration can cover the light-transmitting perforation 512. Light-transmitting through-hole 512 is vertically arranged throughout. Providing light-transmitting through-hole 512 and mounting counterbore 511 prevents diffuse reflection of the light signal emitted by transmitter 41, which could cause receiver 42 to receive the light signal prematurely and cause errors. In this embodiment, mounting counterbore 511 is threadedly connected to transmitter 41, and light-transmitting through-hole 512 corresponds to the axial core of tube body 21.
[0056] Combine Figure 7As shown, in this embodiment, a conical fitting surface 513 is provided at the upper end of the base 51, and the lower end of the conical bottom surface of the conical screen cover 22 is fitted with the conical fitting surface 513. A stopper 5134 is provided in the center of the conical fitting surface 513, and the end edge of the opening at the lower end of the conical screen cover 22 is fitted with the stopper 5134. In this embodiment, the emitter mounting frame 5 also includes a collar 52, which is arranged above the base 51. A group of connecting plates 53 are circumferentially provided at the lower end of the collar 52. The bottom of the connecting plate 53 is connected to the base 51, and the collar 52 is sleeved on the outer wall of the tube body 21. The collar 52 and the base 51 are connected by the connecting plate 53. The emitter mounting frame 5 is hollowed out as a whole, which can ensure the circulation of the solution.
[0057] Combine Figure 5 As shown, in this embodiment, the conical screen cover 22 includes an integrally connected conical bottom 221 and an annular sleeve 222. The conical bottom 221 is disposed below the annular sleeve 222, which is sleeved on the outer wall of the tube body 21. The conical surface on the inner side of the conical bottom 221 fits against the bottom of the tube body 21, thereby limiting the position of the conical screen cover 22 relative to the tube body 21. When the conical bottom 221 is separated from the bottom edge of the tube body 21, the annular sleeve 222 can prevent a gap from forming between the conical screen cover 22 and the tube body 21, so that the pills inside the tube body 21 can leak out through the gap. In this embodiment, a limiting groove is provided on the inner wall of the ring 52, and the top of the annular sleeve 222 is arranged in the limiting groove on the inner wall of the ring 52. Therefore, in this embodiment, the conical screen cover 22 is embedded as a whole between the ring 52 and the conical fitting surface 513 of the launcher mounting frame 5. The overall fixing effect is firm, and when the hanging basket 2 reciprocates up and down, the conical screen cover 22 can be effectively prevented from falling off relative to the launcher mounting frame 5.
[0058] Combine Figure 4 and Figure 6 As shown, in this embodiment, the hanging basket 2 includes an upper limit plate 23 and a lower limit plate 24. The upper limit plate 23 is set at the upper end of a group of tube bodies 21, and a group of tube bodies 21 are passed through the lower limit plate 24. The upper limit plate 23 and the lower limit plate 24 are provided with limit holes adapted to the tube bodies 21; it also includes a connecting rod 25, which passes through the upper limit plate 23 and the lower limit plate 24. The outer wall of the connecting rod 25 is provided with a group of positioning nuts 251. The positioning nuts 251 realize the axial positioning of the upper limit plate 23 and the lower limit plate 24 relative to the connecting rod 25. The upper end of the connecting rod 25 is connected to the lifting drive device 12. The connecting rod 25 is driven by the lifting drive device 12, thereby realizing the up and down movement of the hanging basket 2 as a whole. It should be noted that the upper end of the limit hole corresponding to the tube body 21 on the upper limit plate 23 is provided with a radially inwardly extending eaves to realize the limiting of the upper end of the tube body 21.
[0059] Combine Figure 6 and Figure 7As shown, in this embodiment, the connecting rod 25 is a hollow tube with two open ends. The lower end of the connecting rod 25 extends to correspond to the launcher 41. The connecting rod 25, which is a hollow tube, is used to pass a group of wires from the launcher 41 through it to prevent the wires from swinging, entanglement, and interference when the hanging basket 2 moves up and down. In this embodiment, a group of wire grooves 252 are circumferentially provided at the lower end of the connecting rod 25. Each group of wire grooves 252 corresponds to a group of launchers 41. A limit cap 253 is connected to the bottom of the connecting rod 25. The wire grooves 252 are used to lead out the wires, and the limit cap 253 can limit the lower end of the wires.
[0060] Combine Figure 4 As shown, in this embodiment, the hanging basket 2 also includes a support plate 26, which is connected to the lower limit plate 24 via a set of bolts. The upper end of the support plate 26 is in contact with the bottom surface of the base 51. The support plate 26 is fixed to the bottom of the launcher mounting frame 5 using bolts and nuts. This overall structure improves the secure connection between the launcher mounting frame 5 and the conical screen cover 22 relative to the tube body 21. In this embodiment, the top of the collar 52 is in contact with the upper limit plate 23. The entire structure is also removable, making it easy to clean and maintain.
[0061] Combine Figure 5 and Figure 6 As shown, in this embodiment, a floating head 421 is sheathed around the outside of the receiver 42. The outer edge of the floating head 421 is shaped to conform to the inner edge of the tube body 21. The receiving opening of the receiver 42 extends below the floating head 421. The outer edge of the floating head 421 is provided with a set of vertically extending notches 422. It should be noted that when the tube body 21 is immersed in the beaker 3, the top of the tube body 21 is always above the water surface of the beaker 3. The receiver 42 is mounted on the floating head 421. During use, when the hanging basket 2 is immersed in the solution in the beaker 3, the floating head 421 is placed entirely into the tube body 21. The floating head 421 floats above the solution in the tube body 21. At this time, the receiving opening of the receiver 42 is always immersed below the liquid surface in the tube body 21. This ensures that the only medium between the transmitter 41 and the receiver 42 during the vertical movement of the hanging basket 2 is the solution inside the tube body 21. This prevents the receiver 42 from leaving the water surface, causing light emitted from the transmitter 41 to refract, thereby preventing the receiver 42 from receiving the signal in a timely manner. Therefore, the accuracy of the timing of the end point of the disintegration time limit can be guaranteed. It should be noted that if the receiver 42 is directly sunk to the bottom of the tube body 21, the movable space of the pills placed in the tube body 21 will be squeezed, thereby affecting the disintegration test results. Among them, the shape of the outer edge of the floating head 421 is adapted to the inner edge of the tube body 21, which can ensure the positioning of the receiving port of the receiver 42. In this embodiment, the positions of the receiving port and the transmitting port of the receiver 42 and the transmitter 41 correspond to the axis core of the tube body 21. The notch 422 is provided to prevent the floating head 421 from causing airtight blockage of the tube body 21.
[0062] Combine Figure 1and Figure 2 As shown, in this embodiment, a mounting plate 254 is provided on the top of the connecting rod 25. The mounting plate 254 is provided with a wire through-hole 255 for passing the wire extending from the receiver 42. The linear motion assembly 122 includes a lifting rod 124, a rotating transmission member 121 extending from the upper end of the disintegration apparatus body 1, and an extension plate 125 on the rotating transmission member 121. A pair of suspension rods 126 are fixed to the linear motion assembly 122, and a pair of induction magnets 123 are connected to the mounting plate 254.
[0063] The technical principles of the present invention have been described above in conjunction with specific embodiments. These descriptions are intended solely to illustrate the principles of the present invention and are not to be construed in any way as limiting the scope of protection of the present invention. Based on the explanations herein, those skilled in the art will be able to conceive of other specific embodiments of the present invention without inventive effort, and such embodiments will fall within the scope of protection of the present invention.
Claims
1. An automatic sensing device for disintegration endpoint, characterized by: include: The disintegration instrument body includes a hanging basket and a lifting drive device that drives the hanging basket to move up and down; The pipe body is installed on the hanging basket, and a conical mesh cover is provided at the bottom of the pipe body, and the diameter of the upper end of the conical mesh cover is larger than the diameter of the lower end; The photoelectric sensor includes a transmitter and a receiver. The transmitter is installed below the conical mesh cover with its transmitting port facing the bottom opening of the conical mesh cover. When the drug sinks to the bottom of the conical mesh cover before complete disintegration, it can block the light signal emitted by the transmitter. The receiver is installed above the conical mesh cover with its receiving port facing the transmitting port of the transmitter. The motion state sensor is used to detect whether the motion state of the hanging basket is in the preset ascending stroke; The lifting drive device includes a rotating transmission member and a linear moving assembly, the rotating transmission member is in transmission connection with the linear moving assembly, the linear moving assembly is connected to the hanging basket, and the rotating transmission member is provided with an induction magnetic block; The motion state sensor includes a Hall sensor, which is arranged on one side of the induction magnetic block. When the rotating transmission member drives the induction magnetic block to rotate to a position corresponding to the Hall sensor, the linear motion component drives the hanging basket to a preset ascending stroke. The motion state sensor includes an acceleration sensor installed on the hanging basket, and when the acceleration sensor receives a signal of upward acceleration, it determines that the hanging basket is in a preset ascending stroke; It also includes a transmitter mounting bracket, which is mounted on the lower end of the tube body and connected to the tube body. The transmitter mounting bracket includes a base, a mounting countersunk hole is provided at the bottom of the base, and the transmitter end is arranged in the mounting countersunk hole. A light-transmitting through-hole is provided at the top of the mounting countersunk hole, and the light-transmitting through-hole corresponds to the transmitter emission port. The hanging basket includes an upper limit plate and a lower limit plate, wherein the upper limit plate is arranged at the upper end of a group of tube bodies, and a group of tube bodies are passed through the lower limit plate, and the upper limit plate and the lower limit plate are provided with limit holes adapted to the tube bodies; It also includes a connecting rod, which passes through the upper limit plate and the lower limit plate. The outer wall of the connecting rod is sleeved with a group of positioning nuts, which realize the axial positioning of the upper limit plate and the lower limit plate relative to the connecting rod. The upper end of the connecting rod is connected to the lifting drive device.
2. The automatic disintegration endpoint sensing device according to claim 1, characterized in that: The connecting rod is a hollow tube with two ends open, and the lower end of the connecting rod extends to correspond to the launcher.
3. An automatic sensing system for disintegration endpoint, characterized in that: The automatic sensing device for disintegration endpoint according to claim 1 comprises: The lifting drive module is used to control the lifting drive device to drive the hanging basket to move up and down; The motion state sensing module is used to detect that the hanging basket is in a preset ascending stroke to activate the photoelectric sensor; Disintegration completion confirmation module, after the photoelectric sensor is activated, it detects whether the drug has completed disintegration; Timing module, used to measure the time from the start to the completion of disintegration.
4. A method for automatically sensing the end point of disintegration time, characterized in that: The automatic sensing device for disintegration endpoint according to claim 1 comprises the following steps: The medicine is loaded into the tube of the hanging basket and placed between the conical mesh cover and the receiver; The tube body is immersed in the solution and the lifting driving device drives the hanging basket to move up and down reciprocatingly; The photoelectric sensor is activated when the hanging basket is detected to be in the preset upward stroke; When the receiver receives the light signal sent by the transmitter, it is determined that the drug has completed disintegration.
Citation Information
Patent Citations
Device for accurately judging end point of disintegration time limit of preparation
CN215493284U
Disintegration time limit inductive sensor capable of preventing refraction interference
CN120084960A