Portable blood glucose detection device and system

Abstract

The invention discloses a portable blood glucose detection device and system, relates to the technical field of blood glucose detection, and aims to solve the technical problems that existing dialysis patient blood glucose detection equipment is low in precision, inconvenient to integrate, easy to pollute in the detection process and poor in precision, the portable blood glucose detection device comprises a shell movably arranged on a dialysis tube and a three-way assembly fixedly arranged on one side in the shell, the bottom end of the shell is provided with an insertion opening matched with the three-way assembly and a plug of a dialysis tube in an inserted connection mode, the center of the top end of the shell is provided with a cavity, a supply assembly used for winding blood glucose test paper rolls is arranged in the cavity, and the side, away from the three-way assembly, of the top end of the shell is provided with a mounting groove. By means of the mode of taking blood in cooperation with a dialysis tube, pain caused by fingertip blood taking is avoided, the problems that a traditional detection mode is complex in operation and prone to infection, and pain is brought to a patient are solved, and the requirements of clinical medical treatment for high precision, intelligence and convenience of blood glucose detection are met.

Description

Technical Field

[0001] The present invention relates to the technical field of blood sugar detection, and more specifically, to a portable blood sugar detection device and system. Background Art

[0002] In the medical field, blood sugar testing is crucial for the diagnosis and treatment of diseases. The traditional fingertip blood test method has significant disadvantages and causes pain to patients, especially when the test is done frequently. The operation is cumbersome, and patients need to prepare a variety of tools by themselves. The operation process has strict requirements on hygiene conditions, and infection may occur if not handled with care.

[0003] Dialysis patients have special physical conditions and frequent blood sugar fluctuations, so they need to monitor their blood sugar closely. Existing photoelectric blood sugar detection devices have poor accuracy and are difficult to meet clinical needs. Although implantable blood sugar detection devices can monitor continuously, they require needle insertion, which not only brings extra pain to patients, but also poses a risk of infection.

[0004] More importantly, the existing blood glucose detection device cannot be easily integrated with the dialysis equipment. At present, the blood glucose detection during the dialysis process is often done by drawing blood from the heparin cap with a needle and then dripping it onto the test paper for measurement. This method is not only cumbersome to operate, but also the blood is easily exposed to the indoor air during the blood drawing process, increasing the risk of contamination. At the same time, it is difficult to ensure that the blood is evenly distributed on the test paper, which seriously affects the accuracy of blood glucose detection, resulting in a significant reduction in the accuracy and reliability of the test results. It cannot meet the urgent needs of clinical medicine for high-precision, intelligent and convenient blood glucose detection. In view of this, we propose a portable blood glucose detection device and system. Summary of the invention

[0005] The purpose of the present invention is to provide a portable blood glucose detection device and system to solve the technical problems of low accuracy, inconvenient integration, easy contamination and poor accuracy of existing blood glucose detection equipment for dialysis patients.

[0006] In order to solve the above technical problems, the present invention provides the following technical solutions: a portable blood sugar detection device, comprising a housing movably placed on a dialysis tube and a three-way assembly fixedly arranged on one side of the housing; The bottom end of the shell is provided with a socket for matching the three-way assembly with the plug of the dialysis tube, and the top center of the shell is provided with a chamber, in which a supply assembly for rolling up the blood glucose test strip is provided; A mounting groove is provided on a side of the top of the housing away from the three-way component, and a control and analysis assembly is fixedly arranged in the mounting groove, a socket for plugging and matching with the control and analysis assembly is centrally arranged on one side of the mounting groove, and an analysis terminal is arranged on one side of the socket, extending into the chamber and matching with the reading area on the test paper; The three-way assembly comprises a three-way tube fixedly arranged in the housing, wherein the three-way tube is provided with a capillary sampling assembly having one end extending into the plug and the other end cooperating with the blood glucose test paper roll; The capillary sampling component includes an electromagnetic valve electrically connected to the control and analysis assembly and an on-off display panel connected to the electromagnetic valve. An outer protective tube A and an outer protective tube B are respectively installed at both ends of the electromagnetic valve. A group of capillary main tubes and a capillary group are respectively fixedly arranged in the outer protective tube A and the outer protective tube B. A group of the capillary main tubes are distributed in the outer protective tube A in a circular shape and at equal intervals. The outer protective tube A and one end of the group of capillary main tubes away from the electromagnetic valve are both provided with matching arc surfaces matching the blood collection area on the test paper. The blood is collected through the capillary structure in a closed channel in cooperation with the dialysis tube, thereby avoiding the pain caused by fingertip blood collection. The integrated detection component does not require the patient to prepare blood collection needles, test strips and other tools by himself, thereby simplifying the operation process. At the same time, the method of directly collecting blood samples from the dialysis tube reduces the contact between blood and the outside air, reduces the risk of infection, solves the problems of cumbersome operation, easy infection and pain for patients in traditional detection methods, and meets the requirements of clinical medicine for high-precision, intelligent and convenient blood glucose detection.

[0007] Preferably, the capillary tube group includes a plurality of primary capillary end tubes, a plurality of secondary capillary end tubes, a plurality of tertiary capillary end tubes, a plurality of quaternary capillary end tubes and a capillary core tube placed in an outer protective tube B, and a plurality of capillary branches are connected in a circular array on the outer edge surface of the capillary core tube, and the plurality of primary capillary end tubes, a plurality of secondary capillary end tubes, a plurality of tertiary capillary end tubes, and a plurality of quaternary capillary end tubes all extend from the outer wall of the outer protective tube B, and the capillary core tube and the plurality of capillary branches all extend from the bottom end of the outer protective tube B.

[0008] Preferably, one end of the three-way tube is provided with a through hole for fixing the outer protective tube A, and the other end of the three-way tube is connected to a heparin cap extending out of the shell, the third end of the three-way tube is connected to a socket for the outer protective tube B to pass through, and one end of the socket extending into the socket is connected to a plug.

[0009] Preferably, the supply assembly includes a synchronous winding mechanism placed between two sides of the chamber and two guide rollers rotatably arranged between two sides of the top of the chamber. The synchronous winding mechanism and the two guide rollers form a winding channel for winding the blood glucose test strip roll.

[0010] Preferably, the synchronous winding mechanism comprises a servo motor fixedly arranged at one side of the bottom of the chamber and two winding rollers symmetrically arranged between two sides of the top of the chamber for collecting the blood glucose test strip rolls to be used and used, one end of each of the two winding rollers is fixedly mounted with a synchronous pulley, and a synchronous belt is commonly mounted on the two synchronous pulleys; One end of the servo motor and one end corresponding to the winding roller are both fixedly mounted with a driving pulley, and a driving belt is commonly mounted on the two driving pulleys.

[0011] Preferably, the winding roller includes a roller body and two end rollers arranged at both ends of the roller body, a card slot for inserting one end of the blood glucose test strip roll is centrally opened on the outer edge surface of the roller body, one of the two end rollers is fixed in the synchronous pulley, and the two end rollers are constructed with buckles for the roller body to be snapped and connected on the side facing the roller body, a limit key is opened in the center of one side of the end roller, and limit grooves corresponding to the limit key are opened at both ends of the roller body.

[0012] Preferably, an operation panel is fixedly installed at one end of the shell away from the three-way component, and the operation panel is electrically connected to the control and analysis assembly, a fixed socket for matching the dialysis tube is fixedly installed at the bottom end of the shell, a protective cover is hingedly fitted at the top end of the shell, and a protective cover is buckled in the chamber, and an opening is opened at the top end of the shell for fixing the on-off display panel.

[0013] A blood glucose detection system, comprising a portable blood glucose detection device and a blood glucose analysis system used in conjunction with the device, wherein the blood glucose analysis system is built into a control and analysis assembly, and the blood glucose analysis system comprises a test strip switching control module, a data acquisition module, a data analysis module, a result output module, a data communication module, and a model optimization module; The test strip switching control module is used to control the running state of the supply assembly in real time, so that the reading area and sampling area of ​​the test strip on the blood glucose test strip roll are located at the analysis end and the matching arc surface respectively, and the rotation angle of the servo motor is controlled by the formula To achieve, is the rotation angle of the servo motor, The number of grids required to switch the test strip, is the length of each test paper grid, is the radius of the winding roller; The data acquisition module is used to control the opening and closing time of the electromagnetic valve and the amount of blood sample collected, so that the capillary sampling component collects blood samples in the plug and evenly distributes them in the blood sampling area on the test paper. The opening and closing time of the electromagnetic valve is controlled by the formula To achieve, is the target blood sample collection volume, is the capillary cross-sectional area, is the blood flow rate in the capillaries, is the opening and closing time of the solenoid valve; The data analysis module is used to obtain the electrical signal fed back by the test strip through the analysis terminal, and analyze and process it through the blood glucose concentration analysis model to obtain the final blood glucose concentration value; The result output module is used to summarize the final blood glucose concentration values ​​obtained by analysis, generate a blood glucose concentration fluctuation curve, and display the final blood glucose concentration values ​​in real time through the operation panel; The data communication module is used to transmit the blood glucose concentration fluctuation curve and the real-time blood glucose concentration value to the nurse station, and transmit the patient-related characteristics to the data analysis module; The model optimization module is used to update the blood glucose concentration analysis model in combination with the electrical signals obtained in the past.

[0014] Preferably, the final blood glucose concentration value obtained by the analysis and processing using the blood glucose concentration analysis model is performed in the following manner: Through the multi-layer perceptron architecture, the input layer is set to the electrical signal fed back by the blood glucose test strip. and patient-related features, represented as feature vectors ; The hidden layer calculation follows , where It is The output of the neurons in the hidden layer is is the ReLU activation function, and are the weight matrices from the input layer to the hidden layer and from the feature vector to the hidden layer, is the hidden layer bias; The output layer passes Obtaining predicted values ​​of blood glucose concentration based on large models , where is the weight from the hidden layer to the output layer, is the output layer bias; Based on the linear regression model formula Get blood sugar concentration , where and is the fitting coefficient of experimental data; The predicted blood glucose concentration Blood glucose concentration Through the weighted fusion formula Get the final blood glucose concentration value , where is the weight coefficient.

[0015] Preferably, the updating of the blood glucose concentration analysis model in combination with the electrical signals acquired in the past is performed in the following manner: Use the gradient descent optimization algorithm for the linear regression model to update the fitting coefficients of the linear regression model and ; The stochastic gradient descent algorithm is used for the multi-layer perceptron architecture, and the parameter update formula is: , where represents all the parameters of the model, represents the number of iterations, is the learning rate, It is in the parameter The loss function under Among them, the loss function is the mean square error loss function , where It is the actual blood sugar concentration of the patient obtained through medical testing. is the blood glucose concentration value obtained by the model based on the input data.

[0016] Compared with the prior art, the present invention has the following beneficial effects: 1. The present invention avoids the pain caused by fingertip blood collection by cooperating with the dialysis tube to collect blood through the capillary structure in a closed channel. Its integrated detection component does not require patients to prepare blood collection needles, test strips and other tools by themselves, which simplifies the operation process. At the same time, the method of directly collecting blood samples from the dialysis tube reduces the contact between blood and the outside air, reduces the risk of infection, and solves the problems of traditional detection methods that are cumbersome to operate, easy to infect, and bring pain to patients, and meets the requirements of clinical medicine for high-precision, intelligent and convenient blood sugar detection.

[0017] 2. The capillary sampling assembly and capillary tube group designed in the present invention can efficiently collect blood samples using the siphon principle, and through its unique matching arc surface and the unique distribution method of the capillary main tube, ensure that the blood is evenly distributed in the blood collection area on the test paper, effectively overcoming the problem of uneven blood distribution in existing detection methods, providing reliable guarantee for subsequent accurate blood glucose detection, further improving the detection accuracy, ensuring the accuracy and stability of the test results, and meeting the requirements of clinical medicine for high-precision detection.

[0018] 3. The present invention also integrates a test strip switching control module, a data acquisition module, a data analysis module, a result output module, a data communication module and a model optimization module through the blood glucose analysis system. Through the collaborative work of each module, it can not only display the blood glucose test results in real time, generate a blood glucose concentration fluctuation curve and transmit it to the nurse station to achieve intelligent management, but also update the blood glucose concentration analysis model in combination with past data through the model optimization module, continuously improve the accuracy and reliability of the test, further meet the clinical medical needs for intelligent and continuous optimization of blood glucose testing, and adapt to the personalized testing requirements of different patients. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] Figure 1This is a schematic diagram of the use state of the present invention when it is assembled on a dialysis tube; Figure 2 It is a schematic diagram of the local structure of the present invention and the dialysis tube when they are in a separated state; Figure 3 It is a partial structural cross-sectional view of the three-way assembly and the dialysis tube in the present invention in an assembled state; Figure 4 It is a schematic diagram of the structure of the capillary sampling component in the present invention; Figure 5 It is a schematic diagram of the local structure of the capillary group in the present invention; Figure 6 It is a schematic diagram of the internal structure of the present invention; Figure 7 It is a schematic diagram of the internal structure of the present invention in a cross-sectional state; Figure 8 It is a structural schematic diagram of the blood sugar test strip roll placed on the synchronous winding mechanism in the present invention, and the analysis end and the capillary sampling component are in a matching state; Fig. 9 It is a structural schematic diagram of the synchronous winding mechanism in the present invention; Fig.10 It is a schematic diagram of the partial structure of the winding roller in the present invention.

[0020] Description of the numbers in the figure: 1. Shell; 101. Socket; 102. Chamber; 2. Three-way assembly; 201. Three-way pipe; 202. Socket; 203. Heparin cap; 3. Dialysis tube; 301. Plug; 4. Supply assembly; 401. Guide roller; 5. Blood glucose test strips; 6. Control and analysis assembly; 601. Plug socket; 602. Analysis terminal; 7. Capillary sampling assembly; 701. Solenoid valve; 702. On / off display panel; 703. Outer protective tube A; 704. Outer protective tube B; 705. Capillary main tube; 706. Matching arc surface; 8. Capillary tube group; 801. primary capillary end tube; 802. secondary capillary end tube; 803. tertiary capillary end tube; 804. quaternary capillary end tube; 805. capillary core tube; 806. capillary branch tube; 9. Synchronous winding mechanism; 901. servo motor; 902. synchronous pulley; 903. synchronous belt; 904. driving pulley; 905. driving belt; 10. Winding roller; 1001. Roller body; 1002. End roller; 1003. Slot; 1004. Buckle; 1005. Limit key; 1006. Limit slot; 11. Operation panel; 12. Fixed card holder; 13. Protective cover; 14. Protective cover. DETAILED DESCRIPTION

[0021] Embodiment 1: Figures 1 to 10 As shown, the present invention relates to a portable blood sugar detection device, comprising a housing 1 movably placed on a dialysis tube 3 and a three-way assembly 2 fixedly arranged on one side of the housing 1; The bottom end of the housing 1 is provided with a socket 101 for plugging and mating with the three-way assembly 2 and the plug 301 of the dialysis tube 3, and the top center of the housing 1 is provided with a chamber 102, in which a supply assembly 4 for rolling up the blood glucose test strip roll 5 is provided; A mounting groove is provided on one side of the top of the housing 1 away from the three-way assembly 2, and a control and analysis assembly 6 is fixedly arranged in the mounting groove, a socket 601 for plugging and matching with the control and analysis assembly 6 is centrally arranged on one side of the mounting groove, and an analysis terminal 602 extending into the chamber 102 and matching with the reading area on the test paper is arranged on one side of the socket 601; The three-way assembly 2 includes a three-way tube 201 fixedly arranged in the housing 1, and a capillary sampling assembly 7 is arranged in the three-way tube 201, one end of which extends into the plug 301 and the other end of which cooperates with the blood glucose test paper roll 5; The capillary sampling component 7 includes a solenoid valve 701 electrically connected to the control and analysis assembly 6 and an on-off display panel 702 connected to the solenoid valve 701. An outer protective tube A703 and an outer protective tube B704 are respectively installed at both ends of the solenoid valve 701. A group of capillary main tubes 705 and a capillary tube group 8 are respectively fixedly arranged in the outer protective tube A703 and the outer protective tube B704. A group of capillary main tubes 705 are distributed in the outer protective tube A703 in a circular shape and at equal intervals. The outer protective tube A703 and a group of capillary main tubes 705 are provided with a matching arc surface 706 that matches the blood collection area on the test paper at one end away from the solenoid valve 701.

[0022] In an embodiment of the present invention, the capillary tube group 8 includes a plurality of primary capillary end tubes 801, a plurality of secondary capillary end tubes 802, a plurality of tertiary capillary end tubes 803, a plurality of quaternary capillary end tubes 804 and a capillary core tube 805 placed in the outer protective tube B704, and a plurality of capillary branches 806 are connected in a ring array on the outer edge surface of the capillary core tube 805, and the plurality of primary capillary end tubes 801, the plurality of secondary capillary end tubes 802, the plurality of tertiary capillary end tubes 803, and the plurality of quaternary capillary end tubes 804 are all extended from the outer wall of the outer protective tube B704, and the capillary core tube 805 and the plurality of capillary branches 806 are all extended from the bottom end of the outer protective tube B704, and the primary capillary end tube 801, the secondary capillary end tube 802, the tertiary capillary end tube 803, the quaternary capillary end tube 804, the capillary core tube 805 and the capillary branch tube 806 all have the same radius. Through the capillary sampling component (7) and the capillary tube group (8), the blood sample can be efficiently collected by using the siphon principle. The unique matching arc surface (706) and the unique distribution method of the capillary main tube (705) ensure that the blood is evenly distributed in the blood collection area on the test paper, effectively overcoming the problem of uneven blood distribution in the existing detection method, providing a reliable guarantee for subsequent accurate blood glucose detection, further improving the detection accuracy, ensuring the accuracy and stability of the detection results, and meeting the requirements of clinical medicine for high-precision detection.

[0023] In an embodiment of the present invention, a through hole is provided at one end of the three-way tube 201 for fixing the outer protective tube A703, and the other end of the three-way tube 201 is connected to a heparin cap 203 extending out of the shell 1, and the third end of the three-way tube 201 is connected to a socket 202 for the outer protective tube B704 to pass through, and one end of the socket 202 extending into the socket 101 is connected to the plug 301.

[0024] In an embodiment of the present invention, the supply assembly 4 includes a synchronous winding mechanism 9 placed between two sides of the chamber 102 and two guide rollers 401 rotatably arranged between two sides of the top of the chamber 102. The synchronous winding mechanism 9 and the two guide rollers 401 form a winding channel for winding the blood glucose test strip roll 5.

[0025] In the embodiment of the present invention, the synchronous winding mechanism 9 includes a servo motor 901 fixedly arranged at one side of the bottom of the chamber 102 and two winding rollers 10 symmetrically arranged between the two sides of the top of the chamber 102 for collecting the standby and used blood glucose test strip rolls 5, one end of each of the two winding rollers 10 is fixedly mounted with a synchronous pulley 902, and a synchronous belt 903 is installed on the two synchronous pulleys 902; A driving pulley 904 is fixedly mounted on one end of the servo motor 901 and one end of the corresponding winding roller 10 , and a driving belt 905 is commonly mounted on the two driving pulleys 904 .

[0026] In an embodiment of the present invention, the winding roller 10 includes a roller body 1001 and two end rollers 1002 arranged at both ends of the roller body 1001, a card slot 1003 for inserting one end of the blood glucose test strip roll 5 is centrally opened on the outer edge surface of the roller body 1001, one of the two end rollers 1002 is fixed in the synchronous pulley 902, and the two end rollers 1002 are constructed with a buckle 1004 for the roller body 1001 to be snapped and connected on the side facing the roller body 1001, a limit key 1005 is opened in the center of one side of the end roller 1002, and both ends of the roller body 1001 are opened with a limit groove 1006 matching the corresponding limit key 1005.

[0027] In an embodiment of the present invention, an operation panel 11 is fixedly installed at one end of the shell 1 away from the three-way component 2, and the operation panel 11 is electrically connected to the control and analysis assembly 6, a fixed holder 12 for matching the dialysis tube 3 is fixedly installed at the bottom end of the shell 1, a protective cover 13 is hingedly fitted at the top end of the shell 1, and a protective cover 14 is buckled in the chamber 102, an opening is opened at the top end of the shell 1 for fixing the on-off display panel 702, and a lithium battery and a charging module are arranged in the control and analysis assembly 6 to achieve power-off use and easy carrying.

[0028] The present invention avoids the pain caused by fingertip blood collection by cooperating with the dialysis tube 3 to collect blood through the capillary structure in a closed channel. Its integrated detection component does not require patients to prepare blood collection needles, test strips and other tools by themselves, which simplifies the operation process. At the same time, the method of directly collecting blood samples from the dialysis tube 3 reduces the contact between blood and the outside air, reduces the risk of infection, and solves the problems of traditional detection methods that are cumbersome to operate, easy to infect, and cause pain to patients, and meets the requirements of clinical medicine for high-precision, intelligent and convenient blood sugar detection.

[0029] Embodiment 2: A portable blood glucose detection system, comprising a portable blood glucose detection device and a blood glucose analysis system used in conjunction with the device, the blood glucose analysis system being built into the control and analysis assembly 6, the blood glucose analysis system comprising a test strip switching control module, a data acquisition module, a data analysis module, a result output module, a data communication module and a model optimization module; The test strip switching control module is used to control the operation state of the supply assembly 4 in real time, so that the reading area and the sampling area of ​​the test strip on the blood glucose test strip roll 5 are respectively located at the analysis end 602 and the matching arc surface 706; The real-time control of the running state of the supply assembly 4 is achieved by controlling the rotation angle of the servo motor 901, according to the formula: , where is the rotation angle of the servo motor 901, The number of grids required to switch the test strip, is the length of each test paper grid, is the radius of the winding roller 10; The data acquisition module is used to control the opening and closing time of the electromagnetic valve 701 and the amount of blood sample collected, so that the capillary sampling component 7 collects blood samples in the plug 301 and evenly distributes the blood samples in the blood sampling area on the test paper; Among them, the opening and closing time of the solenoid valve 701 is controlled according to the formula To achieve, is the target blood sample collection volume, is the capillary cross-sectional area, is the blood flow rate in the capillaries, is the opening and closing time of the solenoid valve 701; Among them, by opening the solenoid valve 701, the blood in the dialysis tube 3, driven by the blood pressure and the pressure difference in the dialysis tube 3, flows into the three-way pipe 201 and the socket 202 through the dialysis tube 3, and is distributed on the surface of the outer protective tube B704. Through the cooperation of the capillary group 8 set in the outer protective tube B704, the blood is drained to the matching arc surface 706 between the outer protective tube A703 and a group of capillary main tubes 705 through a group of capillary main tubes 705 and the capillary group 8 in the outer protective tube B704 based on the capillary siphon principle, and the solenoid valve 701 is closed synchronously, and then the matching arc surface 706 is matched with the sampling area on the blood glucose test strip roll 5, combined with the absorption characteristics of the blood glucose test strip roll 5 for blood, the blood in a group of capillary main tubes 705 is absorbed, so that the blood evenly covers the surface of the sampling area, and the blood sample is collected; The data analysis module is used to obtain the electrical signal fed back by the test strip through the analysis terminal 602, and analyze and process it through the blood glucose concentration analysis model to obtain the final blood glucose concentration value; Among them, the final blood glucose concentration value is obtained by analyzing and processing through the blood glucose concentration analysis model in the following way: a multi-layer perceptron architecture is used, and the input layer is set as the electrical signal fed back by the blood glucose test strip. and patient-related features, represented as feature vectors ; The hidden layer calculation follows: ; In the formula, It is The output of the neurons in the hidden layer is is the ReLU activation function, and are the weight matrices from the input layer to the hidden layer and from the feature vector to the hidden layer, is the hidden layer bias; The output layer passes Obtaining predicted values ​​of blood glucose concentration based on large models , where is the weight from the hidden layer to the output layer, is the output layer bias; Based on the linear regression model formula Get blood sugar concentration , where and is the fitting coefficient of experimental data; The predicted blood glucose concentration Blood glucose concentration Through the weighted fusion formula Get the final blood glucose concentration value , where is the weight coefficient; As another embodiment of the present invention, the patient-related characteristics include basic information of the patient, past medical history, recent diet record, and medication record; When the blood reacts with the chemical substances on the blood glucose test strip 5, an electrical signal is generated, and the electrical signal is collected and transmitted to the control and analysis assembly 6 through the analysis terminal 602. In the control and analysis assembly 6, the blood glucose concentration value is obtained after analysis and processing by a preset blood glucose concentration analysis model; The result output module is used to summarize the final blood glucose concentration values ​​obtained by analysis, generate a blood glucose concentration fluctuation curve, and display the final blood glucose concentration values ​​in real time through the operation panel 11; The data communication module is used to transmit the blood glucose concentration fluctuation curve and real-time blood glucose concentration value to the nurse station, and transmit patient-related characteristics to the data analysis module; The model optimization module is used to update the blood glucose concentration analysis model in combination with the electrical signals obtained in the past.

[0030] Among them, the blood glucose concentration analysis model is updated in combination with the electrical signals obtained in the past, and the following method is used: Use the gradient descent optimization algorithm for the linear regression model to update the fitting coefficients of the linear regression model and ; The stochastic gradient descent algorithm is used for the multi-layer perceptron architecture, and the parameter update formula is: ; In the formula, represents all parameter weights and biases of the model, represents the number of iterations, is the learning rate, It is in the parameter The loss function under As another embodiment of the present invention, the loss function is a mean square error loss function: ; In the formula, It is the actual blood sugar concentration of the patient obtained through medical testing. is the blood glucose concentration value obtained by the model based on the input data.

[0031] The blood glucose analysis system integrates the test strip switching control module, data acquisition module, data analysis module, result output module, data communication module and model optimization module. Through the collaborative work of each module, it can not only display the blood glucose test results in real time, generate the blood glucose concentration fluctuation curve and transmit it to the nurse station to realize intelligent management, but also update the blood glucose concentration analysis model in combination with past data through the model optimization module, continuously improve the accuracy and reliability of the test, further meet the clinical medical needs for intelligent and continuous optimization of blood glucose testing, and adapt to the personalized testing requirements of different patients.

[0032] Working principle: This embodiment provides a portable blood sugar detection device and system. When in use, the prepared blood sugar test strip roll 5 is installed on the surface of the roller body 1001, and one end of the blood sugar test strip roll 5 is pulled to make it cross the two guide rollers 401 from above and one end is inserted into the end roller 1002 on the other roller body 1001 and pre-wound, so as to adjust the initial position of the test strip on the blood sugar test strip roll 5 so that the reading area and the sampling area are respectively placed at the analysis end 602 and the matching arc surface 706, and then the protective cover 14 and the protective cover 13 are closed in turn to complete the arrangement of the device; The arrangement can be completed by placing the device on the dialysis tube 3 that has been placed in the patient's body, by making the fixing base 12 snap on the surface of the dialysis tube 3, and by making the plug 301 inserted into the socket 101 and plugged with the socket 202; The device is turned on through the operation panel 11 to start working. First, the solenoid valve 701 is controlled to open through the data acquisition module, so that a group of capillary main tubes 705 in the outer protective tube A703 are connected to the capillary tube group 8 in the outer protective tube B704. The blood sample is collected in the plug 301 through a plurality of primary capillary end tubes 801, a plurality of secondary capillary end tubes 802, a plurality of tertiary capillary end tubes 803, a plurality of quaternary capillary end tubes 804, a capillary core tube 805 and a plurality of capillary branch tubes 806. Based on the siphon principle, the blood sample enters the group of capillary main tubes 705 through the opened solenoid valve 701, and the blood sample is evenly distributed in the blood collection area on the blood glucose test paper roll 5 by combining the matching arc surface 706 opened on the outer protective tube A703 and the group of capillary main tubes 705, so as to realize the collection of the blood sample; After the blood sample is collected, the data analysis module obtains the electrical signal through the reading area on the blood glucose test strip 5 through the analysis terminal 602, and analyzes and processes it through the blood glucose concentration analysis model to obtain the final blood glucose concentration value, and then summarizes the final blood glucose concentration value through the result output module to generate a blood glucose concentration fluctuation curve, and displays the final blood glucose concentration value in real time through the operation panel 11; After completing a single blood glucose test, the rotation angle of the servo motor 901 is controlled by the test strip switching control module, and the two driving pulleys 904 provided with a driving belt 905 are driven to rotate by the servo motor 901, so that the two winding rollers 10 are driven to rotate synchronously through the two synchronous pulleys 902 provided with a synchronous belt 903, so as to realize the movement of the blood glucose test strip roll 5 set thereon, thereby adjusting the test strip on the blood glucose test strip roll 5 so that its reading area and sampling area are respectively placed at the analysis end 602 and the matching arc surface 706, so as to facilitate re-testing.

[0033] The embodiments of the present invention disclose preferred embodiments, but are not limited thereto. A person skilled in the art can easily understand the spirit of the present invention based on the above embodiments and make different extensions and changes. However, as long as they do not deviate from the spirit of the present invention, they are all within the protection scope of the present invention.

Claims

1. A portable blood sugar detection device, characterized in that: It comprises a housing (1) movably placed on a dialysis tube (3) and a three-way assembly (2) fixedly arranged on one side of the housing (1); The bottom end of the housing (1) is provided with a socket (101) for mating with the three-way assembly (2) and the plug (301) of the dialysis tube (3), and the top center of the housing (1) is provided with a chamber (102), and a supply assembly (4) for rolling up a blood glucose test strip roll (5) is provided in the chamber (102); A mounting groove is provided on a side of the top of the housing (1) away from the three-way assembly (2), and a control and analysis assembly (6) is fixedly arranged in the mounting groove; a socket (601) for plugging and cooperating with the control and analysis assembly (6) is centrally arranged on one side of the mounting groove, and an analysis terminal (602) is arranged on one side of the socket (601) to extend into the chamber (102) and to cooperate with a reading area on a test paper; The three-way assembly (2) comprises a three-way tube (201) fixedly arranged in the housing (1), wherein the three-way tube (201) is provided with a capillary sampling assembly (7) having one end extending into the plug (301) and the other end cooperating with the blood glucose test paper roll (5); The capillary sampling assembly (7) comprises a solenoid valve (701) electrically connected to the control and analysis assembly (6) and an on / off display panel (702) connected to the solenoid valve (701); an outer protective tube A (703) and an outer protective tube B (704) are respectively installed at two ends of the solenoid valve (701); a group of capillary main tubes (705) and a capillary tube group (8) are respectively fixedly arranged in the outer protective tube A (703) and the outer protective tube B (704); a group of capillary main tubes (705) are distributed in the outer protective tube A (703) in an annular shape and at equal intervals; and a matching arc surface (706) matching a blood sampling area on a test paper is provided on both ends of the outer protective tube A (703) and the group of capillary main tubes (705) away from the solenoid valve (701).

2. A portable blood sugar detection device according to claim 1, characterized in that: The capillary tube group (8) comprises a plurality of primary capillary end tubes (801), a plurality of secondary capillary end tubes (802), a plurality of tertiary capillary end tubes (803), a plurality of quaternary capillary end tubes (804) and a capillary core tube (805) arranged in an outer protective tube B (704); a plurality of capillary branch tubes (806) are connected in a ring array on the outer edge surface of the capillary core tube (805); the plurality of primary capillary end tubes (801), the plurality of secondary capillary end tubes (802), the plurality of tertiary capillary end tubes (803) and the plurality of quaternary capillary end tubes (804) all extend from the outer wall of the outer protective tube B (704); and the capillary core tube (805) and the plurality of capillary branch tubes (806) all extend from the bottom end of the outer protective tube B (704).

3. A portable blood sugar detection device according to claim 1, characterized in that: One end of the three-way tube (201) is provided with a through hole for fixing the outer protective tube A (703), and the other end of the three-way tube (201) is connected to a heparin cap (203) extending out of the shell (1), and the third end of the three-way tube (201) is connected to a socket (202) for the outer protective tube B (704) to pass through, and one end of the socket (202) extending into the socket (101) is connected to a plug (301).

4. A portable blood sugar detection device according to claim 1, characterized in that: The supply assembly (4) comprises a synchronous rewinding mechanism (9) disposed between two sides of the chamber (102) and two guide rollers (401) rotatably disposed between two sides of the top of the chamber (102); the synchronous rewinding mechanism (9) and the two guide rollers (401) form a rewinding channel for rewinding the blood glucose test strip roll (5).

5. A portable blood sugar detection device according to claim 4, characterized in that: The synchronous rewinding mechanism (9) comprises a servo motor (901) fixedly arranged on one side of the bottom of the chamber (102) and two rewinding rollers (10) symmetrically arranged between two sides of the top of the chamber (102) for collecting the blood glucose test strip rolls (5) to be used and after use, wherein a synchronous belt pulley (902) is fixedly mounted on one end of each of the two rewinding rollers (10), and a synchronous belt (903) is mounted on both of the two synchronous belt pulleys (902); A driving pulley (904) is fixedly mounted on one end of the servo motor (901) and one end corresponding to the winding roller (10), and a driving belt (905) is mounted on both driving pulleys (904).

6. A portable blood sugar detection device according to claim 5, characterized in that: The winding roller (10) comprises a roller body (1001) and two end rollers (1002) arranged at both ends of the roller body (1001); a slot (1003) for inserting one end of a blood glucose test strip roll (5) is centrally provided on the outer edge surface of the roller body (1001); one of the two end rollers (1002) is fixedly arranged in the synchronous pulley (902); and a buckle (1004) for snapping and connecting the roller body (1001) is constructed on one side of the two end rollers (1002) facing the roller body (1001); a limit key (1005) is provided at the center of one side of the end roller (1002); and limit grooves (1006) corresponding to the limit key (1005) are provided at both ends of the roller body (1001).

7. A portable blood sugar detection device according to claim 1, characterized in that: An operation panel (11) is fixedly mounted on one end of the shell (1) away from the three-way assembly (2), and the operation panel (11) is electrically connected to the control and analysis assembly (6). A fixed holder (12) for matching the dialysis tube (3) is fixedly mounted on the bottom end of the shell (1). A protective cover (13) is hingedly mounted on the top end of the shell (1), and a protective cover (14) is buckled in the chamber (102). An opening is provided at the top end of the shell (1) for fixing the on / off display panel (702).

8. A blood glucose detection system, comprising the portable blood glucose detection device according to any one of claims 1 to 7 and a blood glucose analysis system used in conjunction with the device, wherein the blood glucose analysis system is built into a control and analysis assembly (6), characterized in that: The blood sugar analysis system comprises: The test strip switching control module is used to control the operating state of the supply component (4) in real time, so that the reading area and the sampling area of ​​the test strip on the blood glucose test strip roll (5) are respectively located at the analysis end (602) and the matching arc surface (706), and the rotation angle of the servo motor (901) is controlled by the formula To achieve, is the rotation angle of the servo motor (901), The number of grids required to switch the test strip, is the length of each test paper grid, is the radius of the winding roller (10); The data acquisition module is used to control the opening and closing time of the electromagnetic valve (701) and the amount of blood sample collected, so that the capillary sampling component (7) collects the blood sample in the plug (301) and distributes it evenly on the blood collection area on the test paper. The opening and closing time of the electromagnetic valve (701) is controlled by the formula To achieve, is the target blood sample collection volume, is the capillary cross-sectional area, is the blood flow rate in the capillaries, is the opening and closing time of the solenoid valve (701); A data analysis module, used to obtain the electrical signal fed back by the test strip through the analysis terminal (602), and to analyze and process it through a blood glucose concentration analysis model to obtain a final blood glucose concentration value; A result output module is used to summarize the final blood glucose concentration values ​​obtained by the analysis, generate a blood glucose concentration fluctuation curve, and display the final blood glucose concentration values ​​in real time through an operation panel (11); A data communication module is used to transmit the blood glucose concentration fluctuation curve and real-time blood glucose concentration value to the nurse station and transmit patient-related characteristics to the data analysis module; The model optimization module is used to update the blood glucose concentration analysis model in combination with the electrical signals obtained in the past.

9. A blood sugar detection system according to claim 8, characterized in that: The final blood glucose concentration value obtained by the analysis and processing using the blood glucose concentration analysis model is performed in the following manner: Through the multi-layer perceptron architecture, the input layer is set to the electrical signal fed back by the blood glucose test strip. and patient-related features, represented as feature vectors ; The hidden layer calculation follows , where It is The output of the neurons in the hidden layer is is the ReLU activation function, and are the weight matrices from the input layer to the hidden layer and from the feature vector to the hidden layer, is the hidden layer bias; The output layer passes Obtaining predicted values ​​of blood glucose concentration based on large models , where is the weight from the hidden layer to the output layer, is the output layer bias; Based on the linear regression model formula Get blood sugar concentration , where and is the fitting coefficient of experimental data; The predicted blood glucose concentration Blood glucose concentration Through the weighted fusion formula Get the final blood glucose concentration value , where is the weight coefficient.

10. A blood sugar detection system according to claim 9, characterized in that: The updating of the blood glucose concentration analysis model in combination with the electrical signals obtained in the past is performed in the following manner: Use the gradient descent optimization algorithm for the linear regression model to update the fitting coefficients of the linear regression model and ; The stochastic gradient descent algorithm is used for the multi-layer perceptron architecture, and the parameter update formula is: , where represents all the parameters of the model, represents the number of iterations, is the learning rate, It is in the parameter The loss function under Among them, the loss function is the mean square error loss function , where It is the actual blood sugar concentration of the patient obtained through medical testing. is the blood glucose concentration value obtained by the model based on the input data.

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