Compound herbal multifunctional health-preserving fragrant moxibustion

Abstract

The invention relates to the technical field of traditional Chinese medicine health preserving, and discloses a compound herbal multifunctional health preserving fragrant moxibustion, which comprises 48 traditional Chinese medicines such as agilawood, cistanche, cynomorium songaricum and the like, and is prepared by adopting superfine grinding, gradient mixing and low-temperature rolling processes. The fragrant moxibustion can simultaneously achieve the four effects of warming the kidney and strengthening yang, regulating qi and blood, clearing away heat and toxic materials and strengthening the spleen and stomach through acupuncture point moxibustion therapy, and is effective for male dysfunction, chronic fatigue syndrome, gastrointestinal dysfunction and the like.

Description

Technical Field

[0001] The present invention discloses a compound herbal multi-functional health-care moxibustion stick, which relates to the technical field of traditional Chinese medicine health care. Background Art

[0002] Moxibustion, as a traditional Chinese medicine therapy, has a history of thousands of years. By generating warm stimulation to acupoints through burning moxa floss, it can achieve the effects of warming meridians and dispelling cold, and supporting yang and consolidating collapse. However, traditional moxibustion has the following limitations: (1) single component, only using moxa floss as the moxibustion material, lacking targeted drug compatibility; (2) limited efficacy, mainly used for deficiency-cold syndromes, with limited efficacy for complex chronic diseases; (3) insufficient safety, moxibustion smoke contains harmful substances such as tar, and long-term use may cause respiratory problems; (4) inconvenient to use, requiring professional operation and difficult to popularize for family health care.

[0003] In recent years, some Chinese medicine formula moxibustion sticks have emerged on the market, and their efficacy has been improved by adding other medicinal materials. However, the existing products generally have the following problems: (1) unreasonable compatibility, not following the principle of monarch, minister, assistant, and envoy in traditional Chinese medicine, and the medicinal effects are dispersed; (2) simple process, large particle size of the crushed medicinal materials, and insufficient release of active ingredients; (3) unclear indications, lacking scientific verification data; (4) some products add toxic medicinal materials, posing safety hazards.

[0004] Chinese Patent CN102423411A discloses a golden moxibustion stick for treating kidney deficiency, which is composed of 5 traditional Chinese medicines such as polygonatum officinale, cistanche salsa, morinda officinalis, cuscutae chinensis, and moxa floss, but does not contain ingredients for tonifying qi and nourishing blood, and has poor efficacy for patients with both yin and yang deficiency. Chinese Patent CN110680903B discloses an agarwood moxibustion stick and its preparation method. Although it adds multiple medicinal materials, the specific compatibility ratio and synergistic action mechanism are not described. Therefore, it is of great practical significance to develop a new type of health-care moxibustion stick with scientific ingredient compatibility, advanced technology, and clear indications. Summary of the Invention

[0005] The technical problem to be solved by the present invention is to overcome the problems in the prior art and provide a compound herbal multi-functional health-care moxibustion stick, so as to solve the above problems.

[0006] To achieve the above object, the present invention provides the following technical solution: A compound herbal multi-functional health-care moxibustion stick is made from the following raw materials in parts by weight: 45 - 55 parts of Aquilaria sinensis, 45 - 55 parts of Cistanche deserticola, 18 - 22 parts of Cynomorium songaricum, 45 - 55 parts of Astragalus membranaceus, 8 - 12 parts of Lycium barbarum, 8 - 12 parts of Chinese date, 8 - 12 parts of Epimedium brevicornu, 18 - 22 parts of Puerariae flos, 18 - 22 parts of Leonurus japonicus, 45 - 55 parts of Glycyrrhiza uralensis, 28 - 32 parts of Mentha haplocalyx, 18 - 22 parts of Poria cocos, 28 - 32 parts of Pueraria lobata, 38 - 42 parts of Rosa roxburghii, 48 - 52 parts of Actinidia chinensis, 23 - 27 parts of Citrus reticulata Blanco, 13 - 17 parts of Panax ginseng, 23 - 27 parts of Ganoderma lucidum spore powder, 18 - 22 parts of Gastrodia elata, 18 - 22 parts of Taraxacum mongolicum Hand.-Mazz., 58 - 62 parts of Eriobotrya japonica, 38 - 42 parts of Eriobotrya japonica flower, 28 - 32 parts of Eucommia ulmoides leaves, 18 - 22 parts of Eugenia caryophyllata, 58 - 62 parts of Cassia obtusifolia, 28 - 32 parts of Lonicera japonica, 28 - 32 parts of Houttuynia cordata Thunb., 18 - 22 parts of Morus alba L., 18 - 22 parts of Zingiber officinale Rosc., 33 - 37 parts of Imperata cylindrica Beauv., 28 - 32 parts of Nelumbo nucifera Gaertn., 48 - 52 parts of honey, 18 - 22 parts of Codonopsis pilosula, 28 - 32 parts of Ostrea gigas, 38 - 42 parts of Foeniculum vulgare Mill., 8 - 12 parts of Zanthoxylum bungeanum Maxim., 18 - 22 parts of Pogostemon cablin, 18 - 22 parts of Sophora japonica L., 13 - 17 parts of Piper nigrum L., 28 - 32 parts of Angelica sinensis, 16 - 20 parts of Atractylodes macrocephala Koidz., 18 - 22 parts of Spatholobus suberectus Dunn, 13 - 17 parts of Endothelium corneum gigeriae galli, 3 - 7 parts of American ginseng, 8 - 12 parts of Tsaoko fruit, 13 - 17 parts of Cinnamomum cassia Presl, 8 - 12 parts of Laurus nobilis L., 8 - 12 parts of Cornus officinalis Sieb. et Zucc., 13 - 17 parts of Salvia miltiorrhiza Bunge, 3 - 7 parts of Fritillaria cirrhosa D. Don, 18 - 22 parts of Dendrobium nobile Lindl., 2 - 3 parts of Strychnos nux-vomica L., 8 - 12 parts of Perilla frutescens (L.) Britt., 8 - 12 parts of Momordica grosvenori Swingle, 3 - 7 parts of Sesamum indicum L., 8 - 12 parts of Nelumbo nucifera Gaertn, 8 - 12 parts of Euryale ferox Salisb., and the balance is Glycyrrhiza uralensis.

[0007] Preferably, the Strychnos nux-vomica is strictly processed before use to reduce toxicity, and the content of Strychnos nux-vomica in the raw materials is 2.2 - 2.8 parts.

[0008] Preferably, the raw materials contain 1 - 3 parts of Crocus sativus.

[0009] Preferably, the raw materials are ultrafinely pulverized to 800 - 1200 mesh, and the ultrafine pulverization time is 15 - 30 minutes.

[0010] Preferably, the preparation process includes: classifying and pre-treating the medicinal materials according to their effects, mixing them by gradient mixing method, and making rolls at low temperature after adding honey; the rotation speed of gradient mixing is 20 - 40 rpm, and the temperature of making rolls at low temperature is ≤ 45 °C.

[0011] Preferably, the diameter of the moxa stick is 1.8 - 2.2 cm and the length is 15 - 18 cm.

[0012] Preferably, the combustion temperature of the moxa stick is controlled at 180 - 220 °C.

[0013] Preferably, when the aromatic moxibustion is stored, it is vacuum-packed in an aluminum foil bag and needs to be placed in a cool, dry and ventilated environment, with the temperature controlled at 10-25°C and the relative humidity controlled at 40%-60%.

[0014] Preferably, the aromatic moxibustion is applicable to acupoints such as Shenque, Guanyuan, Mingmen, etc.

[0015] Preferably, the aromatic moxibustion can be used to prepare drugs for treating male sexual dysfunction; The aromatic moxibustion can be used to prepare health products for conditioning chronic fatigue syndrome.

[0016] Compared with the prior art, the beneficial effects of the present invention are as follows: Scientific compatibility: Adopting the principle of monarch, minister, assistant and envoy in the prescription, the main drugs (such as agarwood and cistanche) warm the kidney and strengthen yang, the ministerial drugs (such as astragalus and ginseng) supplement qi and nourish blood, the adjuvant drugs (such as dandelion and honeysuckle) clear heat and detoxify, and the envoy drugs (such as licorice and honey) harmonize all the drugs to form a multi-target synergistic effect.

[0017] Process innovation: Adopting ultrafine comminution technology to improve the utilization rate of medicinal materials, using gradient mixing method to ensure the uniformity of components, and low-temperature rolling process to retain the activity of heat-sensitive components.

[0018] Safe and controllable: Determining the safe dosage of nux vomica through orthogonal experiments and cooperating with licorice to detoxify, so that LD50>5000mg / kg.

[0019] Multi-functional conditioning: This aromatic moxibustion has curative effects on male sexual dysfunction, chronic fatigue syndrome and gastrointestinal dysfunction.

[0020] Safe and environmentally friendly: Using natural herbal formula, the tar content in the combustion products is reduced compared with traditional moxa sticks, and the CO emissions are reduced. Detailed implementation manners

[0021] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the protection scope of the present invention.

[0022] The compound herbal multi-functional health-preserving aromatic moxibustion includes the following technical solutions: Embodiment 1: Basic formula Raw material composition: 50 parts of Aquilaria sinensis, 50 parts of Cistanche deserticola, 20 parts of Cynomorium songaricum, 50 parts of Astragalus membranaceus, 10 parts of Lycium barbarum, 10 parts of Ziziphus jujuba, 10 parts of Epimedium brevicornu, 20 parts of Puerariae flos, 20 parts of Leonurus japonicus, 50 parts of Glycyrrhiza uralensis, 30 parts of Mentha haplocalyx, 20 parts of Poria cocos, 30 parts of Pueraria lobata, 40 parts of Rosa roxburghii, 50 parts of Actinidia chinensis, 25 parts of Citrus reticulata Blanco, 15 parts of Panax ginseng, 25 parts of Ganoderma lucidum spore powder, 20 parts of Gastrodia elata, 20 parts of Taraxacum mongolicum, 60 parts of Eriobotrya japonica, 40 parts of Eriobotrya japonica flower, 30 parts of Eucommia ulmoides leaf, 20 parts of Syzygium aromaticum, 60 parts of Cassia obtusifolia, 30 parts of Lonicera japonica, 30 parts of Houttuynia cordata, 20 parts of Morus alba leaf, 20 parts of Zingiber officinale, 35 parts of Imperata cylindrica, 30 parts of Nelumbo nucifera leaf, 50 parts of honey, 20 parts of Codonopsis pilosula, 30 parts of Ostrea gigas, 40 parts of Foeniculum vulgare, 10 parts of Zanthoxylum bungeanum, 20 parts of Pogostemon cablin, 20 parts of Sophora japonica, 15 parts of Piper nigrum, 30 parts of Angelica sinensis, 18 parts of Atractylodes macrocephala, 20 parts of Spatholobus suberectus, 15 parts of Endothelium corneum gigeriae galli, 5 parts of Panax quinquefolius, 10 parts of Tsaoko fruit, 15 parts of Cinnamomum cassia, 10 parts of Laurus nobilis, 10 parts of Evodia rutaecarpa, 15 parts of Salvia miltiorrhiza, 5 parts of Fritillaria cirrhosa, 20 parts of Dendrobium officinale, 2.5 parts of Strychnos nux-vomica, 10 parts of Perilla frutescens, 10 parts of Momordica grosvenori, 5 parts of Sesamum indicum, 10 parts of Nelumbo nucifera Gaertn, 10 parts of Euryale ferox Salisb, and the balance of Glycyrrhiza uralensis.

[0023] The preparation process includes the following steps: First step, raw material pretreatment Impurity removal: Place all traditional Chinese medicine raw materials on a clean screening table, and remove light impurities such as dust and leaf fragments by winnowing; use screening equipment to select a sieve with an appropriate aperture according to the size of the medicinal materials to remove impurities such as larger sand and non-medicinal parts.

[0024] Cleaning: For some medicinal materials with soil or stains on the surface, such as Poria cocos and Atractylodes macrocephala, wash them by flowing water. Control the water flow rate and time during cleaning to avoid the loss of active ingredients. For example, the cleaning time of Poria cocos is controlled within 3 - 5 minutes, and the water flow rate should be just enough to wash away the surface soil. After cleaning, place the medicinal materials in a well-ventilated place to dry naturally or use a low-temperature drying equipment (temperature controlled at 40 - 50 °C) for preliminary drying to reduce the moisture content of the medicinal materials to 10% - 15%.

[0025] Processing: Strychnos nux-vomica: Process it separately. First, soak Strychnos nux-vomica in clean water for 24 hours, changing the water 2 - 3 times during this period to remove some toxic components. Then take out the soaked Strychnos nux-vomica, place it in a pot, add an appropriate amount of sand, and heat and stir-fry over medium heat until the surface of Strychnos nux-vomica bulges, turns brownish-brown, and the inside turns dark brown and has small bubbles, then take it out, sieve off the sand, and let it cool. After cooling, crush the Strychnos nux-vomica to 1000 meshes, and then soak it in glycyrrhiza water (prepared by boiling glycyrrhiza and water in a ratio of 1:3) for 24 hours and then dry it.

[0026] Other medicinal materials: They shall be processed according to their characteristics. For example, dry ginger is stir-fried. Place dry ginger in a hot pan, heat it with medium fire, keep turning it over continuously, stir-fry until the surface is black and the inside is brownish, then take it out and let it cool. Honeysuckle is processed by steaming. Place honeysuckle in a steamer, steam it with high fire for 5 - 10 minutes, then take it out and dry it in the sun to enhance its effect of clearing heat and detoxifying.

[0027] Step 2: Crushing treatment Except for nux vomica, the other medicinal materials are divided into an aphrodisiac group (agarwood, cistanche, cynomorium songaricum, etc.), a qi - tonifying group (astragalus membranaceus, ginseng, codonopsis pilosula, etc.), a heat - clearing group (dandelion, honeysuckle, houttuynia cordata, etc.) according to their effects. Put each group of medicinal materials into an ultrafine pulverizer and crush them to 800 meshes. During the crushing process, control the crushing time and temperature to avoid the loss of active ingredients due to excessive temperature. The crushing time for each time is controlled within 15 - 20 minutes, and at the same time, use air cooling or water cooling to control the temperature of the crushing chamber below 30°C.

[0028] Step 3: Mixing process Adopt the gradient mixing method. First, add the pre - treated nux vomica powder to the aphrodisiac group medicinal material powder, put it into a three - dimensional motion mixer, and mix it at a speed of 20 - 30 revolutions per minute for 30 minutes to make the nux vomica powder evenly dispersed in the aphrodisiac group medicinal material powder.

[0029] Then add the qi - tonifying group medicinal material powder to the above - mixed powder and continue to mix it in the three - dimensional motion mixer at the same speed for 30 minutes.

[0030] Then add the heat - clearing group and other groups of medicinal material powders in turn. After each addition, conduct a 30 - minute mixing operation to ensure that all kinds of medicinal material powders are fully and evenly mixed.

[0031] Step 4: Making and forming into rolls Heat the honey to 60°C for pre - heating, then slowly add it to the mixed medicinal material powder, and at the same time stir it with a stirrer. The stirring speed is controlled at 30 - 40 revolutions per minute, and the stirring time is 20 - 30 minutes to make the humidity reach about 55%.

[0032] Use a roll - making machine to make the medicine powder with adjusted humidity into incense moxibustion with a diameter of 2.0 cm and a length of 16 cm. During the roll - making process, control the pressure and speed of the roll - making machine to ensure the compactness and appearance quality of the incense moxibustion. The roll - making pressure is controlled at 0.5 - 1 MPa, the speed is controlled at 5 - 8 pieces per minute, and the roll - making compactness: density is 1.2 - 1.5 g / cm³.

[0033] Step 5: Drying and packaging Put the made incense moxibustion into a low - temperature drying oven, set the temperature to 40°C, and dry it for 48 hours to reduce the water content of the incense moxibustion to 8% - 10%.

[0034] The quality of the moxa cones after drying is inspected. After passing the inspection, they are sealed and packaged using moisture-proof and insect-proof aluminum foil bags to ensure the quality stability of the moxa cones during storage and transportation.

[0035] The moxa cones produced by this process burn evenly, have a pleasant aroma, and release active ingredients stably.

[0036] Example 2: Enhanced formula Based on Example 1, add 2 parts of saffron and adjust the content of strychnine seeds to 2.8 parts.

[0037] Preparation process: The basic preparation process is the same as that of Example 1. However, during the raw material pretreatment stage, saffron needs to be treated separately. Saffron is precious and its active ingredients are volatile. It is screened at a low temperature (0 - 5°C) to remove impurities, and then pulverized to 1000 mesh using low-temperature pulverization technology (temperature controlled below 10°C). During the mixing stage, finally add the saffron powder to the already mixed other medicinal material powders and then conduct a 30-minute mixing operation to ensure the even distribution of saffron. It is effective for severe impotence patients.

[0038] Example 3: Special formula for children Adjust the raw material composition: Remove irritating medicinal materials such as strychnine seeds and black pepper, and add 20 parts of pseudostellaria root and 30 parts of Chinese yam.

[0039] The preparation process includes the following steps: First step, raw material pretreatment Pretreatment of pseudostellaria root and Chinese yam: After cleaning pseudostellaria root and Chinese yam, cut them into thin slices with a thickness controlled at 2 - 3 mm, and then use low-temperature drying (40 - 45°C) to reduce the water content to about 10%. The dried pseudostellaria root and Chinese yam are pulverized to 1000 mesh using air flow pulverization technology.

[0040] The pretreatment of other medicinal materials is the same as that of Example 1. However, during the cleaning process, further strictly control the cleaning time and water flow rate to avoid excessive loss of active ingredients.

[0041] Second step, pulverization and mixing The pulverization process is the same as that of Example 1. However, during mixing, since the ingredients in the special formula for children are relatively mild, the mixing time can be appropriately extended to 40 minutes to ensure the full and even mixing of various medicinal material powders.

[0042] Third step, rolling and drying The rolling process is the same as that of Example 1. However, during the rolling process, adjust the pressure of the rolling machine to be slightly lower than that of the moxa cones with the adult formula to ensure that the texture of the special moxa cones for children is softer. The drying process is the same as that of Example 1. After safety testing, children have no adverse reactions when using it, and it is effective for anorexia.

[0043] Example 4: Process Optimization The air jet milling technology (1200 mesh) is adopted, and 0.5% lecithin is added as a dispersant during the mixing process.

[0044] The preparation process includes the following steps: The first step, air jet milling All pretreated medicinal materials are separately put into an air jet mill for milling. The air jet mill uses high-speed air flow to make the material particles collide and rub against each other for milling. During the milling process, the air flow speed and pressure are controlled to mill the medicinal materials to 1200 mesh. For example, the air flow speed is controlled at 300 - 400 m / s, and the pressure is controlled at 0.6 - 0.8 MPa. At the same time, the milled particles are screened through a grading device to ensure meeting the required particle size requirements.

[0045] The second step, mixing and adding a dispersant During the gradient mixing process, when all the medicinal material powders are added to a three-dimensional motion mixer, 0.5% of lecithin based on the total powder weight is added as a dispersant. Lecithin has good emulsifying and dispersing effects, which can make various medicinal material powders mix more evenly. After adding lecithin, continue to mix at a speed of 20 - 30 revolutions per minute for 40 minutes to ensure that the dispersant fully plays its role.

[0046] The third step, subsequent processes The processes of rolling and drying are the same as those in Example 1. Compared with the traditional process, the release rate of active ingredients is increased by 40%, and the combustion stability is enhanced.

[0047] Example 5: Menopause Conditioning Formula Add 15 parts of Bupleurum chinense and 20 parts of Glossy Privet Fruit, and remove Strychnos nux-vomica.

[0048] Example 6: Special Formula for Diabetes Add 10 parts of Coptis chinensis and 30 parts of Rehmannia glutinosa, and reduce the honey dosage to 30 parts.

[0049] Supplementary Toxicological Data: Long-term toxicity test: Rats were continuously given 3 times the clinical dosage for 3 months without toxic reactions.

[0050] Skin irritation test: The skin irritation index of rabbits is 0.5 (no irritation).

[0051] Storage Stability Data: Accelerated test: The content of active ingredients ≥ 90% under the conditions of 40℃ / 75%RH for 6 months.

[0052] Room temperature retention observation: The degradation rate of active ingredients < 5% in 24 months.

[0053] The above are only the preferred embodiments of the present invention, and do not limit the patent scope of the present invention. Any equivalent structure or equivalent process transformation made by using the content of the specification of the present invention, or directly or indirectly applied in other related technical fields, shall be similarly included in the patent protection scope of the present invention.

Claims

1. Compound herbal multifunctional health-preserving incense moxibustion, characterized in that: The invention is made of the following raw materials in parts by weight: 45-55 parts of agarwood, 45-55 parts of Cistanche deserticola, 18-22 parts of Cynomorium songaricum, 45-55 parts of Astragalus, 8-12 parts of Lycium barbarum, 8-12 parts of red dates, 8-12 parts of Epimedium, 18-22 parts of Pueraria lobata, 18-22 parts of Leonurus japonicus, 45-55 parts of Licorice, 28-32 parts of Mint, 18-22 parts of Poria, 28-32 parts of Pueraria lobata, 38-42 parts of Rosa roxburghii, 4 parts of Kiwi fruit 8-52 parts, tangerine peel 23-27 parts, ginseng 13-17 parts, ganoderma lucidum spore powder 23-27 parts, gastrodia elata 18-22 parts, dandelion 18-22 parts, loquat leaf 58-62 parts, loquat flower 38-42 parts, eucommia leaf 28-32 parts, clove 18-22 parts, cassia seed 58-62 parts, honeysuckle 28-32 parts, houttuynia cordata 28-32 parts, mulberry leaf 18-22 18-22 parts of dried ginger, 33-37 parts of Imperata root, 28-32 parts of lotus leaf, 48-52 parts of honey, 18-22 parts of Codonopsis pilosula, 28-32 parts of oyster, 38-42 parts of fennel, 8-12 parts of Zanthoxylum bungeanum, 18-22 parts of Patchouli, 18-22 parts of Sophora japonica, 13-17 parts of black pepper, 28-32 parts of Angelica sinensis, 16-20 parts of Atractylodes macrocephala, 18-22 parts of Millettia reticulata, 13-17 parts of chicken's gizzard lining, 3-7 parts of American ginseng, 8-12 parts of amomum villosum, 13-17 parts of cinnamon bark, 8-12 parts of bay leaf, 8-12 parts of cornus officinalis, 13-17 parts of salvia miltiorrhiza, 3-7 parts of Fritillaria cirrhosa, 18-22 parts of dendrobium, 2-3 parts of strychnos nux vomica, 8-12 parts of perilla, 8-12 parts of momordica grosvenori, 3-7 parts of black sesame, 8-12 parts of lotus seeds, 8-12 parts of Euryale ferox, and the remainder is liquorice.

2. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The strychnine is strictly processed before use to reduce toxicity, and the content of strychnine in the raw material is 2.2-2.8 parts.

3. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The raw materials contain 1-3 parts of saffron.

4. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The raw materials are ultrafinely ground to 800-1200 meshes, and the ultrafine grinding time is 15-30 minutes.

5. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The preparation process includes: pre-treating the medicinal materials according to their efficacy, mixing them by gradient mixing method, adding honey and then rolling them at low temperature; the gradient mixing speed is 20-40rpm, and the low temperature rolling temperature is ≤45°C.

6. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The diameter of the moxibustion stick is 1.8-2.2 cm and the length is 15-18 cm.

7. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The moxibustion combustion temperature is controlled at 180-220°C.

8. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The incense moxibustion is suitable for acupoints such as Shenque, Guanyuan, Mingmen, etc.

9. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The incense moxibustion can be used to prepare medicines for treating male dysfunction.

10. The compound herbal multifunctional health-preserving incense moxibustion according to claim 1, characterized in that: The incense moxibustion can be used to prepare health products for regulating chronic fatigue syndrome.