Diagnosis and treatment integrated endoscopic catheter

By setting up the accommodating space for the imaging assembly and ablation assembly on the catheter probe and using the ablation laser beam designed with the inclined surface, the problems of difficulty in compressing the overall size of the catheter, loss of energy of the ablation laser and instability of the system are solved, miniaturizing the catheter and safety and reliability of the system are achieved.

CN120167862APending Publication Date: 2025-06-20SHENZHEN INST OF ADVANCED TECH CHINESE ACAD OF SCI

Patent Information

Application Number
CN202510596262.7
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2025-05-09
Publication Date
2025-06-20

AI Technical Summary

Technical Problem

The existing interventional multimodal imaging and ablation integrated catheter technology has problems such as difficulty in compressing the overall size of the catheter, energy loss and system instability due to the need to be reflected by a reflective prism, and large space occupied by liquid lenses and their electronic control equipment.

Method used

A diagnosis and treatment integrated endoscope catheter is designed. By setting a first accommodation space and a second accommodation space on the catheter probe, the imaging component and the ablation component are placed respectively. The laser beam of the imaging component is emitted to one side of the second accommodation space, and the laser exit end surface of the ablation component is an inclined surface, and the lesion area of ​​the imaging area is directly laser ablated, simplifying the optical path structure and avoiding energy loss.

Benefits of technology

The catheter is miniaturized, the ablation laser optical path structure is simplified, the energy loss and risk of breakdown caused by reflective prisms is avoided, the stability and safety of the system are improved, and the catheter can enter human blood vessels with a diameter of 3-4 mm or even 1 mm for imaging and treatment.

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Abstract

The invention relates to a diagnosis and treatment integrated endoscopic catheter, and belongs to the technical field of medical instruments. The endoscopic catheter comprises a catheter probe, an imaging assembly and an ablation assembly. A first accommodating space and a second accommodating space are formed in the catheter probe, the first accommodating space is formed in the middle of the catheter probe in the axial direction, and the second accommodating space is formed in the catheter wall of the catheter probe in the axial direction; the imaging assembly is placed in the first accommodating space, laser beams emitted by the imaging assembly are emitted to one side of the second accommodating space, and an imaging area is formed after the laser beams are absorbed by the imaging tissue; the ablation assembly is placed in the second containing space, the laser emitting end face of the ablation assembly is an inclined face, the emitted ablation laser beams are emitted out along the inclination angle of the inclined face, laser ablation is directly conducted on the focus area of the imaging area, and the diagnosis and treatment integrated endoscopic catheter achieves integrated miniaturization integration of the imaging function and the ablation function.
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Description

Technical Field

[0001] This application relates to the technical field of medical devices, and particularly to a diagnostic and therapeutic integrated endoscope catheter. Background Art

[0002] An endoscope is a commonly used medical device, widely used in clinical diagnosis and treatment. With the development of medical technology, endoscopes have evolved from single-observation tools to multifunctional devices integrating diagnosis and treatment. Especially in the field of diagnosis and treatment of intravascular diseases, the progress of endoscope catheter technology enables doctors to accurately locate and treat diseased tissues under minimally invasive conditions.

[0003] Currently, significant progress has been made in the technology of intravascular multimodal imaging and ablation integrated catheters. For example, the patent publication number CN116077175B discloses an intravascular four-modal imaging and ablation integrated catheter, which integrates the optical, acoustic, and electrical paths of photoacoustic / ultrasound / elastic / temperature four-modal imaging and photothermal ablation, and can provide accurate structural component information, temperature distribution information, and tissue hardness difference information of lesion tissues. Another example is that the patent publication number CN116172695B discloses an interventional intravascular multimodal imaging and ablation integrated catheter, which integrates photoacoustic / ultrasound / OCT / temperature four-modal imaging and photothermal ablation functions, and realizes the lateral light output of imaging laser and treatment laser and the focusing depth adjustment of treatment laser.

[0004] In terms of catheter structure design, for example, the interventional intravascular three-modal imaging, ablation, and auxiliary temperature measurement integrated catheter disclosed in the patent publication number CN116138875B integrates photoacoustic, ultrasound, and temperature three-modal imaging components, a laser ablation component, and a multi-wavelength and thermocouple auxiliary temperature detection component inside the metal shell. The patent publication number CN111035449B proposes an ultrasonic laser catheter, in which an ultrasonic probe device and a laser optical fiber are arranged in the tube wall of the tube body, so that the laser changes from the longitudinal axis direction of the tube body to the radial direction of the cross section and then shoots towards the lumen, realizing ablation of target tissues under the monitoring of the ultrasonic probe device.

[0005] In addition, another example is that CN109497950B introduces a photoacoustic coaxial endoscope device, including a photoacoustic catheter, an irradiation light providing component, an ultrasonic component, and a lens group for reflecting or refracting the irradiation light and then focusing it on the central axis of the ultrasonic component, realizing photoacoustic coaxiality and a large photoacoustic coincidence area imaging effect.

[0006] However, the existing interventional intravascular multimodal imaging and ablation integrated catheter technology still has some technical problems:

[0007] First of all, it is difficult to compress the overall size of the catheter, which causes a large technical bottleneck for realizing a miniaturized catheter and is difficult to enter human blood vessels with a diameter of 3 - 4 mm or even within 1 mm.

[0008] Secondly, in the prior art, the ablation laser usually irradiates the diseased tissue after being reflected by a reflection prism, which not only causes laser energy loss, but also complicates the optical path adjustment. Moreover, there is a risk that the high-energy ablation laser may break through the reflection prism, affecting the stability and safety of the system.

[0009] Furthermore, in some designs, the liquid lens and its electronic control equipment used take up a large space, which is not conducive to the miniaturization of the catheter.

[0010] Therefore, there is an urgent need to develop an integrated diagnostic and therapeutic endoscope catheter with a compact structure, a simplified optical path, and high safety and reliability. Summary of the Invention

[0011] The technical problem to be solved by the present invention is to provide an integrated diagnostic and therapeutic endoscope catheter for the existing technical defects of the integrated catheter technology for interventional intravascular multimodal imaging and ablation, such as the difficulty in compressing the overall size of the catheter, the energy loss caused by the ablation laser being reflected by the reflection prism, the high-energy laser may break through the reflection prism and affect the stability and safety of the system, and the large space occupied by the liquid lens and its electronic control equipment, etc., to achieve the miniaturization of the catheter, simplify the optical path structure of the ablation laser, and improve the stability and safety of the system.

[0012] The technical solution adopted by the present invention to solve its technical problems is: to provide an integrated diagnostic and therapeutic endoscope catheter, including: a catheter probe, on which a first accommodation space and a second accommodation space are opened, the first accommodation space is arranged at the middle position of the catheter probe along its axial direction, and the second accommodation space is arranged on the tube wall of the catheter probe along its axial direction; an imaging component, placed in the first accommodation space, the laser beam emitted by the imaging component is emitted to one side of the second accommodation space, and forms an imaging area after being absorbed by the imaging tissue; an ablation component, placed in the second accommodation space, the laser emission end face of the ablation component is an inclined surface, and the emitted ablation laser beam is emitted along the inclination angle of the inclined surface, and directly performs laser ablation on the lesion area of the imaging area.

[0013] As a preferred embodiment, the ablation component includes a high-threshold optical fiber and an optical fiber collimator, and the laser emission end face of the optical fiber collimator is an inclined surface, so that the light spots of the emitted ablation laser beam are consistent and no focusing is required.

[0014] As a preferred embodiment, the inclination angle of the inclined surface is the total reflection angle of the high-threshold optical fiber.

[0015] As a preferred embodiment, the imaging assembly includes a double-clad fiber, a self-focusing lens, and a mirror. The laser beam transmitted through the double-clad fiber is sequentially focused by the self-focusing lens and reflected by the mirror, and then exits to one side of the second accommodation space.

[0016] As a preferred embodiment, the first accommodation space includes an accommodation hole for placing the double-clad fiber and the self-focusing lens, and an accommodation groove for placing the mirror.

[0017] As a preferred embodiment, the front end of the catheter probe is provided with a mounting platform for mounting and placing the ultrasonic transducer. The accommodation groove is opened on the mounting platform and abuts against the accommodation hole.

[0018] As a preferred embodiment, the ultrasonic transducer is connected with an ultrasonic wire.

[0019] As a preferred embodiment, it further includes a spring coil connected to the catheter probe.

[0020] As a preferred embodiment, the rear end of the endoscope catheter is connected with an optoelectronic slip ring for realizing the rotational transmission of optical signals and electrical signals. The spring coil is located between the optoelectronic slip ring and the catheter probe.

[0021] As a preferred embodiment, the inclination angle of the inclined surface is C, then:

[0022] sinC = 1 / n;

[0023] where n is the refractive index of the high-threshold fiber material.

[0024] The beneficial effects of the present application are as follows:

[0025] The embodiment of the present application provides a diagnosis and treatment integrated endoscope catheter that is safer and easier to achieve miniaturized integration. By providing a first accommodation space and a second accommodation space for placing the imaging assembly and the ablation assembly on the catheter probe, the imaging optical path and the ablation optical path are separated, which not only ensures the resolution of the small-core laser imaging but also ensures the high-power transmission of the large-core laser. Moreover, the laser exit end face of the ablation assembly is set as an inclined surface with a total reflection angle, so that the ablation laser can directly irradiate the imaging area without the need to use a reflecting prism to change the propagation direction, simplifying the ablation laser optical path structure and avoiding the risk of energy loss and breakdown caused by the reflecting prism; and the liquid lens and its electronic control equipment are omitted, effectively reducing the radial size of the diagnosis and treatment integrated catheter, enabling it to enter the human blood vessels with a diameter of 3-4 mm or even within 1 mm for imaging and treatment, and thus realizing the miniaturized integration of the catheter.

[0026] It should be understood that the content described in the Summary of the Invention section is not intended to limit the key or important features of the embodiments of the present application, nor is it used to limit the scope of the present application. Other features of the present application will become easily understandable through the following description. BRIEF DESCRIPTION OF THE DRAWINGS

[0027] In conjunction with the accompanying drawings and with reference to the following detailed description, the above and other features, advantages, and aspects of the embodiments of the present application will become more apparent. In the drawings, the same or similar reference numerals denote the same or similar elements, where:

[0028] Figure 1 is a schematic perspective view of the integrated diagnosis and treatment endoscope catheter according to an embodiment of the present application;

[0029] Figure 2 is a schematic cross-sectional view of the integrated diagnosis and treatment endoscope catheter according to an embodiment of the present application;

[0030] Figure 3 is a schematic perspective view of the catheter probe according to an embodiment of the present application;

[0031] Figure 4 is a schematic diagram of the irradiation area of the laser and the sound field range of the ultrasound when the integrated diagnosis and treatment endoscope catheter according to an embodiment of the present application is working;

[0032] Figure 5 is a schematic diagram of the rear-end connection structure of the integrated diagnosis and treatment endoscope catheter according to an embodiment of the present application.

[0033] Reference Numerals:

[0034] 1. Catheter probe; 10. First accommodation space; 11. Second accommodation space; 101. Accommodation hole; 102. Accommodation groove; 12. Mounting platform; 121. Ultrasonic wire threading groove;

[0035] 2. Imaging assembly; 21. Double-clad optical fiber; 22. Self-focusing lens; 23. Reflecting mirror;

[0036] 3. Ablation assembly; 30. Inclined surface; 31. High-threshold optical fiber; 32. Fiber collimator;

[0037] 4. Ultrasonic transducer; 41. Ultrasonic wire;

[0038] 5. Spring coil;

[0039] 6. Optoelectronic slip ring. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0040] To make the objectives, technical solutions, and advantages of the embodiments of the present disclosure clearer, the technical solutions in the embodiments of the present disclosure will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present disclosure. Apparently, the described embodiments are some, but not all, of the embodiments of the present disclosure. All other embodiments obtained by those of ordinary skill in the art based on the embodiments in the present disclosure without creative efforts shall fall within the scope of protection of the present disclosure.

[0041] In addition, the technical solutions between the various embodiments of the present application can be combined with each other, but it must be based on the ability of those of ordinary skill in the art to implement. When the combination of technical solutions results in contradictions or cannot be implemented, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection required by the present application.

[0042] Please refer to Figures 1-4 As shown, this embodiment provides a diagnosis and treatment integrated endoscope catheter, which includes a catheter probe 1, an imaging component 2, and an ablation component 3; in combination with Figure 3 As shown, a first accommodation space 10 and a second accommodation space 11 are provided on the catheter probe 1. The first accommodation space 10 is provided at the middle position of the catheter probe 1 along its axial direction, and the second accommodation space 11 is provided on the tube wall of the catheter probe 1 along its axial direction. As Figure 1 shown, the imaging component 2 is placed in the first accommodation space 10, and the laser beam emitted by the imaging component 2 is emitted to the side of the second accommodation space 11 and forms an imaging area after being absorbed by the imaging tissue; the ablation component 3 is placed in the second accommodation space 11, and the laser emission end face of the ablation component 3 is an inclined surface 30, and the emitted ablation laser beam is emitted along the inclination angle of the inclined surface to directly perform laser ablation on the lesion area of the imaging area.

[0043] It should be noted that the catheter probe 1 is made of a medical-grade polymer material, has good biocompatibility and flexibility, and its outer diameter can be 0.5 to 5.0 millimeters, and it can adapt to the bending structures of various lumens in the human body. The front end of the catheter probe is blunt, which is convenient for inserting into human tissues and reduces damage to tissues. The first accommodation space 10 and the second accommodation space 11 are formed by precision machining on the catheter probe 1. The first accommodation space 10 is located at the middle position of the catheter probe 1 and is used to accommodate the double-clad optical fiber 21 and the self-focusing lens 22. The part of the first accommodation space adapted to the diameters of the double-clad optical fiber 21 and the self-focusing lens 22 is in a cylindrical structure; the second accommodation space 11 is located on the tube wall of the catheter probe 1 and is in an open groove structure.

[0044] Among them, as Figure 1 、 Figure 2As shown, the imaging component 2 includes a double-clad fiber 21, a self-focusing lens 22, and a mirror 23. The double-clad fiber 21 is used to transmit the imaging laser beam. Its core diameter can be preferably 9 microns, the inner cladding diameter is 125 microns, and the outer cladding diameter is 250 microns. The self-focusing lens 22 is used to focus the laser beam transmitted by the double-clad fiber 21. Its diameter is 0.5 mm and the focal length is 2 mm. The mirror is used to reflect the laser beam focused by the self-focusing lens towards one side of the second accommodation space. The reflective film of the mirror can be a metal film such as a silver film or an aluminum film, or other dielectric films, with a reflectivity greater than 98%, and the reflection angle is preferably between 32° and 41°.

[0045] The laser beam transmitted through the double-clad fiber 21 is sequentially focused by the self-focusing lens 22 and reflected by the mirror 23, and then exits towards one side of the second accommodation space 11. The emitted laser beam is scattered and absorbed by the tissue after irradiating the tissue. The scattered light is collected by the double-clad fiber and transmitted back to the detection system, and an optical tomographic image of the tissue is formed through the interference principle. The wavelength of the emitted laser beam can be 400 - 2000 nm, and further preferably 780 nm, 1064 nm, 1310 nm, 1720 nm, etc., and is specifically selected according to the actual tissue composition. The laser beam is absorbed by the tissue after irradiating the tissue, forming an imaging area that can clearly show the microscopic structure of the tissue.

[0046] Combined Figure 4 As shown, when the catheter of the embodiment of the present invention works, a simple description of the irradiation area of the laser and the sound field range of the ultrasound is as follows:

[0047] When used for optical coherence tomography (OCT) imaging, a single-mode fiber of the double-clad fiber 21 is used to transmit the laser light source. After passing through the self-focusing lens 22 and the mirror 23, it irradiates on the sample to complete the excitation process. The light reflected back from the sample passes through the mirror 23 and the self-focusing lens 22, and is transmitted back into the single-mode fiber of the double-clad fiber 21 to complete the detection process.

[0048] When used for photoacoustic imaging, a single-mode or multi-mode fiber of the double-clad fiber 21 is used to transmit the laser light source. After passing through the self-focusing lens 22 and the mirror 23, it irradiates on the sample to complete the excitation process. The generated photoacoustic signal (i.e., ultrasonic wave) is detected by the ultrasonic transducer 4.

[0049] When used for optical imaging such as fluorescence and near-infrared spectrum (NIRS), a multimode fiber of the double-clad fiber 21 is used to transmit a laser light source. After passing through a self-focusing lens 22 and a mirror 23, it irradiates the sample to complete the excitation process. The light reflected by the sample passes through the mirror 23 and the self-focusing lens 22 and is transmitted back into the single-mode fiber of the double-clad fiber 21 to complete the detection process.

[0050] After the imaging of multiple modalities is completed and the lesion area is detected, a high-power laser can be emitted by the high-threshold fiber 31. After passing through the fiber collimator 32, a collimated ablation light beam is formed. An inclined surface with a total reflection angle is cut at the exit end face of the fiber collimator 32, and the collimated light beam is emitted from the side to ablate the lesion area. Since the emitted collimated ablation light beam is collimated light, the irradiation spot at each position is basically the same, and no focusing is required.

[0051] As a preferred real-time method, as Figure 4 shown, the collimated ablation light beam emitted from the exit end face with the inclined surface 30 and the imaging laser light beam reflected by the mirror 23 are in the same plane; to further ensure the working coordination of the collimated ablation light beam and the imaging laser light beam and ensure the ablation effect on the lesion area, it is preferably to set the inclined surface 30 and the reflecting surface of the mirror 23 as parallel planes, so as to fully ensure that the collimated ablation light beam and the imaging laser light beam cross the lesion spot synergistically and achieve a more precise ablation effect.

[0052] Combined with Figure 3 shown, the first accommodation space 10 includes an accommodation hole 101 for placing the double-clad fiber 21 and the self-focusing lens 22, and an accommodation groove 102 for placing the mirror 23. The accommodation hole is cylindrical and parallel to the axial direction of the catheter probe; the accommodation groove 102 is a rectangular groove and abuts against the accommodation hole to form an L-shaped spatial structure.

[0053] The double-clad fiber 21 and the self-focusing lens 22 are fixed in the accommodation hole 101, and the mirror 23 is fixed in the accommodation groove 102. The fixing method can use medical epoxy resin glue, which has good biocompatibility and stability. The sizes of the accommodation hole 101 and the accommodation groove 102 are precisely matched with the sizes of the components of the imaging assembly 2 to ensure the stable installation of the imaging assembly and the accurate alignment of the optical path.

[0054] Combined with Figure 2 、 Figure 3As shown in the figure, an installation platform 12 for installing and placing the ultrasonic transducer 4 is provided at the front end of the catheter probe 1. A receiving groove 102 is formed on the installation platform 12 and abuts against the receiving hole. The ultrasonic transducer 4 is installed on the installation platform 12. The ultrasonic transducer 4 is made of piezoelectric ceramic material and can provide structural information of deep tissues, complementing optical imaging. The ultrasonic transducer is connected with an ultrasonic wire, and the ultrasonic wire is formed by stranding multiple copper wires and is used for transmitting ultrasonic signals. Moreover, the receiving groove 102 is formed on the installation platform 12 and abuts against the receiving hole 101 to form a continuous optical path channel. This design enables the optical path of the imaging component and the acoustic path of the ultrasonic transducer to work together to achieve photoacoustic dual-modal imaging and provide more comprehensive tissue information.

[0055] Among them, one end of the ultrasonic wire 41 is connected to the electrode of the ultrasonic transducer 4, and the other end is connected to the electrical signal interface of the optoelectronic slip ring 6 through the ultrasonic wire groove 121 formed inside the catheter probe.

[0056] The ultrasonic wire is used for transmitting the excitation signal and echo signal of the ultrasonic transducer. After the echo signal is amplified by the preamplifier, it is transmitted to the external ultrasonic image processing system through the ultrasonic wire to form an ultrasonic image of the tissue.

[0057] As Figure 2 shown in the figure, the ablation component 3 includes a high-threshold optical fiber 31 and an optical fiber collimator 32. The high-threshold optical fiber 31 is used for transmitting high-power laser, and its core diameter is 125 - 400 microns. The laser output end face of the optical fiber collimator is an inclined surface, making the spots of the output ablation laser beam consistent without the need for focusing.

[0058] It should be noted that the optical fiber collimator 32 and its inclined surface 30 are made by cutting a self-focusing optical fiber. To ensure the collimation or basic collimation of the output spot, according to the specific application scenario and the requirements of the optical system, simulation analysis is carried out with the help of optical design software (such as Zemax, Code V, etc.) to determine the precise length required for cutting the self-focusing optical fiber. One end of the self-focusing optical fiber is fusion-connected to the high-threshold optical fiber, and the other end is cut and polished to form the inclined surface at the output end face. The specific optical fiber cutting method can adopt the existing optical fiber cutting method and will not be elaborated here. The inclined angle of the output end face is the total reflection angle of the high-threshold optical fiber. The total reflection angle of the high-threshold optical fiber depends on the refractive index of the optical fiber material. When light travels from a high refractive index medium to a low refractive index medium, total reflection occurs when the incident angle is greater than the critical angle.

[0059] If the inclination angle of the inclined plane is C, then: sinC = 1 / n; where n is the refractive index of the high-threshold optical fiber material. In this embodiment, the refractive index of the high-threshold optical fiber material used is 1.45, and the refractive index of air is 1. Therefore, the inclination angle C = 43.6 degrees. This design enables the ablation laser beam to be emitted at the optimal angle, directly acting on the lesion area in the imaging area, achieving precise ablation treatment, while avoiding energy loss and improving the ablation efficiency.

[0060] The wavelength of the ablation laser is 400 - 2000 nanometers, and 790 nanometers, 1064 nanometers, 1470 nanometers, etc. can be further preferably selected. After passing through the fiber collimator 32, the ablation laser beam is sufficient to effectively ablate the lesion tissue with minimal thermal damage to the surrounding normal tissue.

[0061] As Figure 5 shown, the integrated diagnosis and treatment endoscope catheter further includes a spring coil 5 connected to the catheter probe 1. The spring coil 5 is wound by a medical stainless steel wire, has good flexibility and torsional performance, can adapt to various curved channels in the human body, improves the controllability of the catheter, and at the same time maintains sufficient thrust transmission ability to ensure that the catheter can reach the target position smoothly.

[0062] The rear end of the endoscope catheter is connected with an optoelectronic slip ring 6 for realizing the rotational transmission of optical signals and electrical signals. The spring coil 5 is located between the optoelectronic slip ring 6 and the catheter probe 1.

[0063] It should be noted that the optoelectronic slip ring 6 consists of a fixed part and a rotating part. The fixed part is connected to the external device, and the rotating part is connected to the spring coil 5. Inside the optoelectronic slip ring 6, there are an optical fiber rotary joint and an electrical signal slip ring. The optical fiber rotary joint adopts the GRIN lens collimation coupling method, with an insertion loss of less than 0.5 dB and a return loss of more than 50 dB; the electrical signal slip ring adopts a precious metal contact ring with a contact resistance of less than 0.1 ohm, and can maintain stable signal transmission during the 360-degree rotation process. The shell of the optoelectronic slip ring is made of medical-grade aluminum alloy material and is connected to the external laser source, ultrasonic system and control system through a special interface to realize the full-function control and signal transmission of the integrated diagnosis and treatment endoscope catheter.

[0064] During use, the integrated diagnosis and treatment endoscope catheter is inserted into the part of the human body to be examined. The catheter probe is driven to rotate and move axially by an external control system. The laser beam of the imaging component scans the tissue surface to form an optical tomography image of the tissue. At the same time, the ultrasonic transducer emits ultrasonic waves and receives echo signals to form an ultrasonic image of the tissue. The doctor analyzes the optical image and the ultrasonic image to determine the location and scope of the lesion area. After the lesion is determined, the ablation component is activated. The ablation laser beam is transmitted to the fiber collimator through a high-threshold optical fiber and emitted through the inclined surface, directly acting on the lesion area for precise ablation treatment. During the treatment process, the imaging component can monitor the ablation effect in real time to ensure the safety and effectiveness of the treatment.

[0065] The above description is only the preferred embodiment of the present application and an explanation of the applied technical principles. Those skilled in the art should understand that the scope of the application involved in the present application is not limited to the technical solution formed by the specific combination of the above technical features, and should also cover other technical solutions formed by any combination of the above technical features or their equivalent features without departing from the aforementioned application concept. For example, the technical solution formed by mutually replacing the above features with the technical features (but not limited to) having similar functions applied in the present application.

Claims

1. An integrated diagnosis and treatment endoscopic catheter, characterized in that: include: A catheter probe, wherein a first accommodating space and a second accommodating space are provided on the catheter probe, wherein the first accommodating space is provided at a middle position of the catheter probe along its axial direction, and the second accommodating space is provided on a tube wall of the catheter probe along its axial direction; An imaging component is placed in the first accommodation space, and a laser beam emitted by the imaging component is emitted toward one side of the second accommodation space, and is absorbed by the imaging tissue to form an imaging area; The ablation component is placed in the second accommodating space. The laser emitting end face of the ablation component is an inclined surface. The emitted ablation laser beam is emitted along the inclined angle of the inclined surface to directly perform laser ablation on the lesion area of ​​the imaging area.

2. The diagnosis and treatment integrated endoscopic catheter according to claim 1, characterized in that: The ablation component includes a high-threshold optical fiber and an optical fiber collimator. The laser emission end face of the optical fiber collimator is an inclined face, so that the light spot of the emitted ablation laser beam is consistent and does not need to be focused.

3. The diagnosis and treatment integrated endoscopic catheter according to claim 2, characterized in that: The inclination angle of the inclined surface is the total reflection angle of the high threshold optical fiber.

4. The diagnosis and treatment integrated endoscopic catheter according to claim 1, characterized in that: The imaging component includes a double-clad optical fiber, a self-focusing lens, and a reflector. The laser beam transmitted through the double-clad optical fiber is sequentially focused by the self-focusing lens and reflected by the reflector before being emitted to one side of the second accommodating space.

5. The diagnosis and treatment integrated endoscopic catheter according to claim 4, characterized in that: The first accommodating space includes an accommodating hole for accommodating the double-clad optical fiber and the self-focusing lens, and an accommodating groove for accommodating the reflecting mirror.

6. The diagnosis and treatment integrated endoscopic catheter according to claim 5, characterized in that: The front end of the catheter probe is provided with a mounting platform for mounting and placing the ultrasonic transducer, and the accommodating groove is arranged on the mounting platform and abuts against the accommodating hole.

7. The diagnosis and treatment integrated endoscopic catheter according to claim 6, characterized in that: The ultrasonic transducer is connected with an ultrasonic wire.

8. The diagnosis and treatment integrated endoscopic catheter according to claim 1, characterized in that: Also included is a spring coil connected to the catheter probe.

9. The diagnosis and treatment integrated endoscopic catheter according to claim 8, characterized in that: The rear end of the endoscopic catheter is connected with a photoelectric slip ring for realizing rotational transmission of optical signals and electrical signals, and the spring coil is located between the photoelectric slip ring and the catheter probe.

10. The diagnosis and treatment integrated endoscopic catheter according to claim 1, characterized in that: The inclination angle of the inclined surface is C, then: sinC = 1 / n; Where n is the refractive index of the high threshold optical fiber material.

Citation Information

Patent Citations

  • A photoacoustic coaxial endoscope, endoscope system and control method

    CN109497950B

  • An ultrasonic laser conduit

    CN111035449B

  • An intravascular quadruple-modality imaging and ablation integrated catheter

    CN116077175B

  • Intravascular trimodal imaging, ablation and auxiliary temperature measurement integrated catheter

    CN116138875B

  • An interventional intravascular multimodal imaging and ablation integrated catheter

    CN116172695B

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