Biological facial cleanser based on natural bioactive components and preparation method thereof

Abstract

The invention discloses a biological facial cleanser based on natural bioactive ingredients and a preparation method thereof.The facial cleanser comprises a composite biological surfactant, a natural active ingredient group, multivitamins, a green auxiliary additive and the balance water, and the facial cleanser has multiple combinations of the effects of moisturizing, oil controlling, whitening, soothing, repairing, inflammation resisting and the like; the requirements of different skin types can be met, and the skin is mild and non-irritant. The preparation method disclosed by the invention is simple and easy for industrial production, and has a wide application prospect.

Description

Technical Field

[0001] The present invention relates to the field of daily chemical products, specifically to the field of cosmetics, and particularly to a biological facial cleanser based on natural bioactive ingredients and a preparation method thereof. Background Art

[0002] Traditional facial cleansing products mostly use chemically synthesized surfactants. Although they have strong cleaning power, they may cause irritation to the skin and are prone to damaging the skin's barrier function after long-term use. In recent years, with the improvement of people's living standards and the increasing awareness of health and environmental protection, consumers' demand for natural, safe and environmentally friendly cosmetics has increased. Biosurfactants and plant extracts have gradually become a research hotspot in the field of cosmetics due to their mild, non-irritating and environmentally friendly characteristics. Therefore, it is of great significance and market prospect to develop a biological facial cleanser mainly composed of natural ingredients, with good cleaning effect, safety, mildness and multiple skin care effects. Summary of the Invention

[0003] To solve the above technical problems, the present invention uses natural biological ingredients, which are mild and non-irritating, and at the same time have multiple skin care effect characteristics. Utilizing the synergistic effect of biosurfactants and functional plant extracts, through nanoemulsion technology and low-temperature processing technology, and at the same time adopting an antibacterial peptide natural preservation system, integrating multiple effects into one.

[0004] The object of the present invention is to provide a biological facial cleanser based on natural bioactive ingredients and a preparation method thereof, which uses a combination of biosurfactants and natural plant extracts to achieve cleaning and skin care effects. The technical solution adopted is: a biological facial cleanser based on natural bioactive ingredients, comprising 5-20% of a composite biosurfactant, 5-25% of a natural active ingredient group, 0.2-3% of a composite vitamin, 0.5-5% of a green auxiliary additive, and the balance being water (deionized water or purified water).

[0005] Further, the composite biosurfactant is composed of two or more combinations of sapindus saponin, sophorolipid, surfactin, tea saponin, betaine, rhamnolipid.

[0006] The natural active ingredient group is composed of three or more functional groups selected from an oil control group, a moisturizing group, a whitening group, a soothing group, a repair group, and an anti-inflammatory group. The natural active ingredients are extracts, fermentation products or derivatives obtained by natural extraction and / or biological fermentation, such as: Oil control group: salicylic acid (naturally extracted), green tea extract, coix seed extract, biota orientalis extract, lavender extract, turmeric extract, prunella vulgaris extract, rosemary extract, etc.; Moisturizing group: hyaluronic acid, ceramide NP, glycerin, shea butter, aloe extract, soy lecithin, gynostemma pentaphyllum extract, lily extract, crithmum maritimum extract, etc.; Whitening group: niacinamide, arbutin, glycyrrhizic acid, ginkgo biloba extract, euphrasia extract, iris lactea pall. var. chinensis extract, rosa multiflora extract, ampelopsis grossedentata extract, epilobium angustifolium extract, etc.; Soothe group: asiaticoside, chamomile extract, saxifraga stolonifera extract, calendula extract, oat extract, cucumber extract, sophora flavescens extract, etc.; Repair group: witch hazel extract, ginseng extract, notoginseng extract, wheat germ peptide, silybum marianum extract, etc.; Anti-inflammatory group: tea polyphenols, licorice extract, ganoderma lucidum extract, carambola extract, gardenia jasminoides ellis extract, grape seed extract, cinnamic acid glucoside, portulaca oleracea extract, etc.

[0007] The compound vitamin is a combination of two or more of vitamin B (such as panthenol), vitamin C (such as ascorbyl glucoside), and vitamin E (such as tocopherol).

[0008] The green auxiliary additives include one or more of the following combinations: Thickeners: xanthan gum, lecithin, soluble starch and its derivatives, trehalose, gelatin, pectin, and natural thickeners such as polysaccharide derivatives; Chelating agents: chitosan, GLDA (tetrasodium glutamate diacetate), and green chelating agents such as octanohydroxamic acid; Preservatives: antimicrobial peptides (such as cecropin, lysozyme, nisin, etc.); PH regulators: citric acid, lactic acid.

[0009] The preparation process of the biotype facial cleanser is as follows:

[0010] S1: Pretreatment Dissolve and mix the natural active ingredients in an aqueous phase at ≤45°C to obtain a natural active ingredient solution; Dissolve and mix the vitamins in an aqueous phase at ≤45°C to obtain a vitamin solution.

[0011] S2: Prepare the functional solution Add a thickener to the aqueous phase at 30°C - 45°C and disperse it by ultrasound (30 kHz, 60 min); Add a chelating agent, the natural active ingredient solution obtained in step S1, and the vitamin solution in sequence, and homogenize at high speed (12000 rpm, 15 min) to obtain a functional solution.

[0012] S3: Prepare the nanoemulsion Dissolve the biosurfactant mixture in an aqueous phase at 35 °C to 45 °C, further emulsify it using a shear emulsifier (10,000 rpm, 30 min), and then further prepare it into a nanoemulsion (particle size D90 ≤ 120 nm) using a high-pressure homogenizer (150 - 200 MPa, 3 times).

[0013] S4: Functional integration Mix the nanoemulsion obtained in step S3 and the functional solution obtained in step S2 evenly, stir at 180 rpm for 15 min, and ensure that the temperature ≤ 45 °C throughout the process.

[0014] S5: pH adjustment and anti-corrosion Add citric acid or lactic acid to pH 6.0 ± 0.4, then inject the aqueous solution of antimicrobial peptide, and stir at 180 rpm for 20 min to obtain the bio-based facial cleanser.

[0015] S6: Sterilization and canning After aseptic treatment, fill it into cans, seal it, and store it in the dark. Beneficial effects

[0016] (1) The present invention uses biosurfactants, which have the characteristics of being natural, mild, and environmentally friendly, can effectively clean the skin, and will not cause irritation to the skin.

[0017] (2) The present invention adds a variety of plant extracts, which have multiple functions such as moisturizing, oil control, repair, whitening, anti-inflammatory, and soothing, and can meet the needs of different skin types.

[0018] (3) The present invention uses antimicrobial peptides as preservatives, which have a broad-spectrum antibacterial effect, are non-irritating to the skin, and can effectively extend the shelf life of the product.

[0019] (4) The preparation method of the present invention is simple, easy to industrialize, and has broad application prospects. Description of the drawings

[0020] Figure 1 It is a flow chart of the preparation method of the present invention. Specific embodiments

[0021] In order to make the purpose and advantages of the present invention clearer, the present invention will be further described below in conjunction with examples and experimental examples. It should be understood that the specific embodiments described herein are only used to explain the present invention and are not used to limit the present invention.

[0022] The following refers to the attached Figure 1 to describe the preferred embodiments of the present invention. Attached Figure 1It is a simplified process flow chart, which only illustrates the basic process of the present invention in a schematic manner. Therefore, it only shows the processes related to the present invention. Those skilled in the art should understand that these embodiments are only used to explain the technical principles of the present invention and do not limit the protection scope of the present invention.

[0023] Example 1:

[0024] Formulation composition: Biosurfactants: sophorolipid (6%), sapindus saponin (5%), surfactin (0.2%); Natural active ingredients: Oil control: salicylic acid (1.0%), coix seed extract (2.0%); Moisturizing: ceramide NP (0.3%), gynostemma pentaphyllum extract (1.5%); Anti-inflammatory: grape seed extract (1.0%), cinnamic acid glucoside (0.8%), licorice extract (1.5%); Soothe: asiaticoside (1.5%), chamomile extract (1.5%), calendula extract (1.0%) Vitamins: vitamin C (0.2%), vitamin E (0.3%); Thickeners: xanthan gum (0.7%), trehalose (2.0%); Chelating agent: octanoyl hydroxamic acid (0.05%); pH regulator: citric acid (0.5%); Preservative: antimicrobial peptide (nisin, 0.15%).

[0025] Preparation process:

[0026] S1. Pretreatment: Dissolve the natural active ingredients in the aqueous phase at 35°C to obtain a natural active ingredient solution; Dissolve vitamin C and vitamin E in the aqueous phase at 35°C to obtain a vitamin solution.

[0027] S2: Prepare a functional solution Add thickeners (xanthan gum, trehalose) to the aqueous phase at 35°C and disperse ultrasonically (30 kHz, 60 min); Add octanoyl hydroxamic acid, the natural active ingredient solution obtained in step S1, and the vitamin solution in sequence, and homogenize at high speed (12000 rpm, 15 min) to obtain a functional solution.

[0028] S3: Prepare a nanoemulsion Dissolve sapindus saponin, sophorolipid, and betaine in an aqueous phase at 42°C, further emulsify using a shear emulsifier (10,000 rpm, 30 min), and then further prepare a nanoemulsion (particle size D90 ≤ 120 nm) using a high-pressure homogenizer (180 MPa, 3 times).

[0029] S4: Functional integration Cool the nanoemulsion obtained in step S3 to ≤ 35°C, add the functional solution obtained in step S2, mix evenly, and stir at 180 rpm for 15 min.

[0030] S5: pH adjustment and preservation Add citric acid to pH 5.8 ± 0.2, then inject the antimicrobial peptide aqueous solution, and stir at 180 rpm for 20 min.

[0031] S6: Sterilization and canning Filter through a 0.22 μm filter membrane and then fill into cans, seal, and store in the dark.

[0032] Example 2:

[0033] Formulation composition: Biosurfactants: sapindus saponin (6%), sophorolipid (5%), betaine (3%); Natural active ingredients: Oil control: coix seed extract (1.5%), Platycladus orientalis leaf extract (1.5%); Moisturizing: hyaluronic acid (1%), soy lecithin (2.0%), lily extract (1.5%); Anti-inflammatory: green tea polyphenols, licorice extract (1.5%); Whitening: niacinamide (1%), ginkgo biloba extract (1%), arbutin (0.6%); Vitamins: vitamin B5 (0.5%), vitamin E (0.3%); Thickener: xanthan gum (1.5%); pH regulator: citric acid (0.5%); Preservative: antimicrobial peptide (0.2%).

[0034] Preparation process: The preparation method is the same as that of Example 1.

[0035] Example 3:

[0036] Formulation composition: Biosurfactants: sapindus saponin (6%), sophorolipid (5%), betaine (3%); Natural active ingredients: Oil control: salicylic acid (1.0%), green tea extract (1.0%), lavender extract (1.0%); Moisturizing: Hyaluronic acid (1%), Soybean lecithin (2.0%), Aloe vera extract (1.5%); Anti-inflammatory: Grape seed extract (1.0%), Cinnamic acid glucoside (0.8%); Repair: Witch hazel extract (1.5%), Milk thistle extract; Vitamins: Vitamin B5 (0.2%), Vitamin E (0.3%); Thickening agents: Xanthan gum (0.9%), Sodium carboxymethyl starch (1.5%); Chelating agent: Octanoyl hydroxamic acid (0.05%); pH regulator: Citric acid (0.45%); Preservative: Antimicrobial peptide (0.25%).

[0037] Preparation process: The preparation method is the same as that in Example 1.

[0038] Experiment

[0039] (1) Antiseptic effect test Experiment purpose: To verify the antibacterial effect of the antimicrobial peptide preservative and compare it with the traditional preservative (paraben).

[0040] Bacteria species: Staphylococcus aureus, Escherichia coli, Candida albicans.

[0041] Test method: The facial cleanser of this patent (containing 0.1% nisin) and the control sample containing 0.2% paraben were respectively inoculated with 10 6 CFU / mL bacteria and cultured at 37°C for 7 days. The colony count (CFU / mL) was measured every 24 hours.

[0042] Results: See Table 1 Comparison of antibacterial effects Bacterial species This patent sample (antimicrobial peptide) Control sample (paraben) Staphylococcus aureus <10 CFU / mL <10 CFU / mL Escherichia coli <10 CFU / mL 1.2×10³ CFU / mL Candida albicans <10 CFU / mL Not detected

[0043] (2) Environmental friendliness analysis Experiment purpose: To verify the biodegradability of biosurfactants.

[0044] Method: Test standard: OECD 301B (aerobic biodegradation rate).

[0045] Samples: Sapindus saponins, sophorolipids, SLS.

[0046] Results: See Table 2 Comparison of biodegradation rates Ingredient 7-day biodegradation rate (%) Sapindus saponins 92.3% Sophorolipid 89.1% SLS 65.4%

[0047] (3) User feedback Samples: 50 volunteers (aged 18 - 50 years, covering dry, neutral, oily and sensitive skin types).

[0048] Evaluation period: Continuously use the product for 28 days and fill out a questionnaire (Likert scale of 5 points).

[0049] Key questions: ① Do you feel that the skin cleansing power is sufficient? ② Do you experience tightness, irritation, or allergies? ③ What is your satisfaction with "oil control", "moisturizing", "whitening", and "soothing"?

[0050] Results: See Table 3 User Feedback Form Item Very satisfied (%) Satisfied (%) Neutral (%) Dissatisfied (%) Detergency 82% 16% 2% 0% Skin irritation 90% 8% 2% 0% Sebum control effect 76% 20% 4% 0% Moisturizing effect 80% 18% 2% 0% Whitening effect 68% 26% 6% 0% Soothe sensitive effect 86% 12% 2% 0%

[0051] Experiment summary (1) The antibacterial effect of the antimicrobial peptide against Gram-negative bacteria (such as Escherichia coli) is better than that of traditional preservatives, supporting the innovation of the "green preservative" of the present invention; (2) The high degradation rate of the biosurfactant meets the green chemistry standards, supporting the environmental protection statement of the present invention; (3) Through the user feedback results, it conforms to the mild and multi-functional technical characteristics of the present invention.

[0052] So far, the technical solution of the present invention has been described in conjunction with the preferred embodiments shown in the drawings. However, it is easy for those skilled in the art to understand that the protection scope of the present invention is obviously not limited to these specific embodiments. Without departing from the principle of the present invention, those skilled in the art can make equivalent changes or substitutions to the relevant technical features, and the technical solutions after these changes or substitutions will all fall within the protection scope of the present invention.

Claims

1. A biological facial cleanser based on natural bioactive ingredients, characterized in that: The invention comprises 5-20% of a composite biosurfactant, 5-25% of a natural active ingredient group, 0.2-3% of a composite vitamin, 0.5-5% of a green auxiliary additive, and the balance is water.

2. The biological cleanser according to claim 1, characterized in that: The composite biosurfactant is a combination of two or more of soapberry saponin, sophorolipid, surfactin, tea saponin, betaine and rhamnolipid.

3. The biological cleanser according to claim 1, characterized in that: The natural active ingredient group is composed of three or more functional groups of an oil control group, a moisturizing group, a whitening group, a soothing group, a repairing group, and an anti-inflammatory group.

4. The biological cleanser according to claim 1, characterized in that: The complex vitamin is a combination of two or more of vitamin B, vitamin C and vitamin E.

5. The biological facial cleanser according to claim 1, characterized in that: The green auxiliary additives include one or more combinations of thickeners, chelating agents, preservatives, and pH regulators.

6. The green auxiliary additive according to claim 5, characterized in that: The thickener is a natural thickener, such as xanthan gum, lecithin, soluble starch and its derivatives, trehalose, gelatin, pectin and polysaccharide derivatives.

7. The green auxiliary additive according to claim 5, characterized in that: The chelating agent is a green chelating agent, such as chitosan, GLDA (tetrasodium glutamate diacetate), and caprylhydroxamic acid.

8. The green auxiliary additive according to claim 5, characterized in that: The preservative is an antimicrobial peptide.

9. The green auxiliary additive according to claim 5, characterized in that: The pH adjuster is citric acid or lactic acid.

10. The method for preparing the biological cleanser according to claim 1, characterized in that: The following steps are involved: S1: Preprocessing Dissolving and mixing the natural active ingredients in an aqueous phase at ≤45°C to obtain a natural active ingredient solution; Dissolving and mixing the vitamins in an aqueous phase at ≤45°C to obtain a vitamin solution; S2: Preparation of functional solution Add thickener to the water phase at 30℃~45℃ and disperse by ultrasonic (30kHz, 60min); Add nanocellulose, chelating agent, natural active ingredient solution obtained in step S1, and vitamin solution in sequence, and homogenize at high speed (12000 rpm, 15 min) to obtain a functional solution; S3: Preparation of Nanoemulsion Dissolve the biosurfactant in a water phase at 35°C to 45°C, mix and compound, further emulsify with a shear emulsifier (10,000 rpm, 30 min), and further prepare into a nanoemulsion (particle size D90 ≤ 120 nm) with a high-pressure homogenizer (150 to 200 MPa, 3 times); S4: Functional Integration The nanoemulsion obtained in step S3 and the functional solution obtained in step S2 were mixed evenly, and stirred at 180 rpm for 15 min, and the temperature was ensured to be ≤45°C throughout the process; S5: pH adjustment and preservation Add citric acid or lactic acid to pH 6.0±0.4, then inject the antimicrobial peptide aqueous solution, stir at 180 rpm for 20 min, and obtain a biological cleanser; S6: Sterilization and canning After aseptic processing, fill it, seal it and store it away from light.

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