Tumor photodynamic therapy device with double laser wavelengths

Abstract

The invention relates to the technical field of photodynamic therapy, and provides a tumor photodynamic therapy device with double laser wavelengths, which comprises a protective shell, a multi-stage cooling assembly is arranged in the protective shell, the multi-stage cooling assembly comprises a driving motor and a heat conduction pipe, the driving motor is welded and fixed in the protective shell, and the heat conduction pipe is arranged in the protective shell. The output end of the driving motor is connected with an output shaft, a first gear is welded and fixed to the output shaft, a fixed net plate is welded and fixed in the protective shell, a dehumidifying net plate is fixed in the protective shell through bolts, a laser therapeutic instrument is fixedly installed in the protective shell, and an optical fiber is connected to the laser therapeutic instrument. The optical fiber is provided with a multifunctional protection assembly. By means of the technical scheme, the problems that in the prior art, a tumor photodynamic therapy device is single in light source, efficient cooling and heat dissipation cannot be conducted, and a used phototherapy head cannot be conveniently protected are solved.

Description

Technical Field

[0001] The present invention relates to the technical field of photodynamic therapy, and specifically, to a tumor photodynamic therapy device with dual laser wavelengths. Background Art

[0002] Photodynamic therapy for tumors is a relatively new tumor treatment method, and its principle is mainly based on the interaction between photosensitizers, light, and oxygen. Tumor cells are destroyed by generating cytotoxic substances, as follows:

[0003] Photosensitizer Enrichment

[0004] Tumor cells are metabolically active, have strong proliferation ability, special cell membrane transport proteins and receptors, and high tumor vascular permeability. Based on this, photosensitizers with specific chemical structures and optical properties can be selectively taken up and retained in tumor tissues, accumulate in organelles such as mitochondria and endoplasmic reticulum in tumor cells, and have less distribution in normal tissues.

[0005] Light Excitation Reaction

[0006] Irradiate the tumor site with light of a specific wavelength that matches the absorption spectrum of the photosensitizer, such as light with wavelengths of 630 nm, 690 nm, etc. emitted by semiconductor lasers. After the photosensitizer absorbs photons, it transitions from the ground state to the excited state, and then undergoes energy transfer with surrounding oxygen molecules to generate singlet oxygen with strong oxidation activity.

[0007] Tumor Destruction

[0008] Singlet oxygen triggers an oxidative stress response in tumor cells, oxidizes cell membrane lipids, attacks proteins and nucleic acids, causing the leakage of intracellular substances, protein denaturation, nucleic acid strand breakage, etc., resulting in apoptosis or necrosis of tumor cells. At the same time, singlet oxygen damages tumor vascular endothelial cells, causing the blood vessel lumen to narrow and block, cutting off the tumor blood supply. In addition, the death of tumor cells releases tumor-associated antigens, activates the body's immune system, triggers a specific anti-tumor immune response, regulates the expression of immune factors and cytokines, and inhibits tumor growth and metastasis.

[0009] In the actual use process of existing clinically applied photodynamic therapy devices, due to the single laser source, it is not possible to perform convenient light source conversion with the change of photosensitizers, and the laser itself will continuously generate a large amount of heat during the actual working process. The conventional heat dissipation mechanism has low heat dissipation efficiency and poor heat dissipation effect, and cannot perform efficient cooling and heat dissipation treatment on the photodynamic therapy device during long-term operation; and existing clinically applied photodynamic therapy devices need to be equipped with auxiliary brackets to complete the erection of the light therapy head to ensure the stability of subsequent laser irradiation treatment work, and cannot provide convenient protection for the used light therapy head, with poor practicability. Therefore, it is necessary to provide a tumor photodynamic therapy device with dual laser wavelengths to meet the needs of users. Summary of the Invention

[0010] The present invention provides a tumor photodynamic therapy device with dual laser wavelengths, which solves the problems in the related art that the tumor photodynamic therapy device cannot efficiently cool and dissipate heat, cannot conveniently and stably position and fix the optical therapy head, and cannot conveniently protect the used optical therapy head.

[0011] The technical solution of the present invention is as follows:

[0012] A tumor photodynamic therapy device with dual laser wavelengths, including a protective housing. A multi-stage cooling component is installed inside the protective housing. The multi-stage cooling component includes a driving motor and a heat conduction pipe. The driving motor is welded and fixed inside the protective housing. The output end of the driving motor is connected to an output shaft. A first gear is welded and fixed on the output shaft. A second gear is meshed with the first gear. A third gear is meshed with the second gear. A screw rod is welded and fixed on the third gear. An insulating box is welded and fixed inside the protective housing. A conveying cylinder is welded and fixed inside the insulating box. One end of the heat conduction pipe is connected to the conveying cylinder, and the other end of the heat conduction pipe is connected to the side end of the top of the insulating box. A first filter plate and a second filter plate are welded and fixed on the protective housing. A fixing net plate is welded and fixed inside the protective housing. A moisture removal net plate is bolted and fixed inside the protective housing. A laser therapy instrument is installed and fixed inside the protective housing. An optical fiber is connected to the laser therapy instrument. An optical therapy head is connected to the optical fiber. A multi-functional protection component is installed on the optical fiber.

[0013] As a preferred solution of the present invention, wherein: the second gears are symmetrically distributed on both sides of the first gear, the second gears correspond to the third gears one by one, the insulating boxes are symmetrically distributed on both sides inside the protective housing, the insulating boxes respectively correspond to the screw rod, the conveying cylinder and the heat conduction pipe one by one, the screw rod is rotatably connected inside the conveying cylinder, and the length of the screw rod is greater than the length of the conveying cylinder.

[0014] As a preferred solution of the present invention, wherein: a refrigerating sheet is installed on the side end of the insulating box, a fixing pipe is connected to the top of the insulating box, a through groove is formed through the heat conduction pipe, a hydraulic rod is installed and fixed on the top of the protective housing, the bottom end of the hydraulic rod is fixedly connected to a connecting rod, and a sliding rod is welded and fixed on the bottom end surface of the connecting rod. The sliding rod penetrates and is slidably connected inside the heat conduction pipe.

[0015] As a preferred solution of the present invention, wherein: the hydraulic rod is fixed at the middle part of the connecting rod, the sliding rods are symmetrically distributed on both sides of the bottom of the connecting rod, the bottom end of the sliding rod is fixedly connected to a sealing block, the length and width of the sealing block are respectively greater than the length and width of the through groove, and the sealing block is in fit with the inner wall of the heat conduction pipe.

[0016] As a preferred solution of the present invention, wherein: a fixing plate is welded and fixed on the heat conduction tube, a first guide groove is penetrated in the fixing plate, a driven shaft is welded and fixed on the second gear, an exhaust fan, a fixing rod and a scraper rod are welded and fixed on the driven shaft, a rotating ring is welded and fixed on the fixing rod, a second guide groove is penetrated on the rotating ring, a first sponge rod is fixedly connected to the rotating ring, and a second sponge rod is fixedly connected to the fixing rod.

[0017] As a preferred solution of the present invention, wherein: the bottom end surface of the fixed plate is arc-shaped, the bottom end surface of the fixed plate is in contact with the outer wall of the rotating ring, the second guide groove and the first sponge rod are evenly distributed on the rotating ring, the first sponge rod is arc-shaped, the fixed rod is evenly distributed on the driven shaft, and the second sponge rod is symmetrically distributed on both sides of the fixed rod.

[0018] As a preferred solution of the present invention, wherein: the multifunctional protective component includes a flexible tube and a support plate, the flexible tube and the support plate are both fixedly connected to the optical fiber, the support plate is fixedly connected with a sealing frame and a connecting plate, the connecting plate is rotatably connected with a first protective frame, the first protective frame is provided with a card slot, the first protective frame is sleeved with a second protective frame, the first protective frames are symmetrically distributed on both sides of the support plate, the first protective frame corresponds one-to-one to the second protective frame, and the card slots are equidistantly distributed on the first protective frame.

[0019] As a preferred solution of the present invention, wherein: a reset spring is welded and fixed on the second protective frame, a clamping rod is welded and fixed on the reset spring, the clamping rod passes through and is slidably connected to the second protective frame, the end of the clamping rod is clamped and connected in a clamping groove, a sealing plate is fixedly connected to the second protective frame, and the sealing plate and the sealing frame are both made of rubber material.

[0020] As a preferred solution of the present invention, wherein: the second protective frame is rotatably connected with a first threaded rod and a rotating cylinder, the first threaded rod is threadedly connected with a connecting frame, the rotating cylinder is slidably connected to the connecting frame, a telescopic sleeve rod is limitedly slidably connected in the rotating cylinder, a second threaded rod is welded and fixed on the telescopic sleeve rod, the second threaded rod is rotatably connected in the connecting frame, a push plate is threadedly connected to the second threaded rod, a plug rod is fixedly connected to the push plate, a rubber piston is fixedly connected to the plug rod, the rubber piston is slidably connected in the plug tube, a rubber suction cup is connected to the plug tube, and the plug tube is fixedly connected in the connecting frame.

[0021] As a preferred solution of the present invention, wherein: the first threaded rod is symmetrically distributed on both sides of the connecting frame, the rotating cylinder is connected to the center of the connecting frame, the plug rod is equidistantly distributed on the push plate, and the plug rod corresponds one-to-one with the plug tube through a rubber piston.

[0022] The working principle and beneficial effects of the present invention are as follows:

[0023] 1. In the present invention, a multi-stage cooling component is provided. The first gear can drive the second gears and the third gears on both sides, and then can drive the screw rod to rotate stably in the conveying cylinder, thereby driving the refrigerated purified water in the heat insulation box to continuously circulate in the heat conduction pipe. Using the heat exchange principle, it can quickly cool the surrounding air, and the cooled air is conveyed to the laser treatment instrument through the exhaust fan to achieve primary efficient cooling; when the laser treatment instrument works for a long time, the through groove can be opened by the drive of the hydraulic rod. At this time, the cooled purified water can be automatically and intermittently conveyed into each first sponge rod and second sponge rod. Using the evaporation heat absorption of water, it can further improve the cooling effect of the surrounding air and achieve secondary efficient cooling of the laser treatment instrument. It can perform primary or secondary cooling treatment according to the working state of the laser treatment instrument, which is energy-saving and environmentally friendly.

[0024] 2. In the present invention, a first filter plate and a second filter plate are provided. Under the action of the first filter plate, the outside air can be filtered at the air inlet, and under the combined action of the first filter plate and the second filter plate, the air circulation inside the device can be realized, ensuring the stability of the overall cooling work of the device. Moreover, during the operation of the exhaust fan, the scraping rod can be automatically rotated by the driven shaft, and then the dust and impurities filtered on the first filter plate can be automatically scraped and cleaned, ensuring the stability of the long-term working state of the first filter plate and preventing the first filter plate from being blocked and affecting the ventilation work.

[0025] 3. In the present invention, a multi-functional protection component is provided. By fitting the second protection frames on both sides and fixing them by rubber suction cups, a convenient and stable sealing protection treatment can be carried out on the working light therapy head, avoiding the light therapy head from being polluted or damaged by accidental touch from the outside, increasing the use safety and stability of the treatment device; and when the light therapy head starts to work, the second protection frames on both sides can be rotated and separated, and also in cooperation with the rubber suction cups, the light therapy head can be conveniently and stably adsorbed and fixed at a suitable irradiation position, ensuring the convenience and stability of the subsequent laser irradiation treatment work; and according to the characteristics of the photosensitizer, the two light therapy heads can be conveniently selected and used, and by using the cooperation of the card slot and the card rod, the working position of the rubber suction cup can be conveniently adjusted according to the actual situation, and by the cooperation drive of the first threaded rod and the connecting frame, the working height of the light therapy head can be conveniently adjusted according to the actual situation, increasing the use diversity and practicality of the treatment device. BRIEF DESCRIPTION OF THE DRAWINGS

[0026] The present invention will be further described in detail below in conjunction with the drawings and specific embodiments.

[0027] Figure 1It is a schematic diagram of the overall structure of the present invention;

[0028] Figure 2 It is a schematic diagram of the connection structure between the protective shell and the second filter plate of the present invention;

[0029] Figure 3 It is a schematic diagram of the connection structure between the protective shell and the moisture removal net plate of the present invention;

[0030] Figure 4 It is a schematic diagram of the connection structure between the first gear and the second gear of the present invention;

[0031] Figure 5 It is a schematic diagram of the connection structure between the screw rod and the heat insulation box of the present invention;

[0032] Figure 6 It is a schematic diagram of the connection structure between the heat insulation box and the conveying cylinder of the present invention;

[0033] Figure 7 It is a schematic diagram of the connection structure between the fixed rod and the rotating ring of the present invention;

[0034] Figure 8 It is the present invention Figure 7 The enlarged structure schematic diagram at position A in;

[0035] Figure 9 It is a schematic diagram of the top view and cross-section of the conveying cylinder of the present invention;

[0036] Figure 10 It is a schematic diagram of the connection structure between the support plate and the sealing frame of the present invention;

[0037] Figure 11 It is a schematic diagram of the connection structure between the first protective frame and the second protective frame of the present invention;

[0038] Figure 12 It is a schematic diagram of the connection structure between the second protective frame and the rotating cylinder of the present invention;

[0039] Figure 13 It is the present invention Figure 12 The enlarged structure schematic diagram at position B in;

[0040] Figure 14 It is a schematic diagram of the connection structure between the rotating cylinder and the telescopic sleeve rod of the present invention;

[0041] Figure 15 It is a schematic diagram of the connection structure between the first threaded rod and the connection frame of the present invention.

[0042] In the figure: 1, protective housing; 2, multi-stage cooling component; 201, drive motor; 202, output shaft; 203, first gear; 204, second gear; 205, third gear; 206, screw rod; 207, heat insulation box; 208, conveying cylinder; 209, heat conduction pipe; 210, refrigeration sheet; 211, fixed pipe; 212, through groove; 213, hydraulic rod; 214, connecting rod; 215, sliding rod; 216, sealing block; 217, fixing plate; 218, first diversion groove; 219, driven shaft; 220, exhaust fan; 221, fixed rod; 222, rotating ring; 223, second diversion groove; 224, first sponge rod; 225, second sponge rod; 226, scraping rod; 3, first filter plate; 4, fixed mesh plate; 5, dehumidifying mesh plate; 6, laser therapeutic apparatus; 7, optical fiber; 8, light therapy head; 9, multi-functional protection component; 901, flexible cylinder; 902, support plate; 903, sealing frame; 904, connecting plate; 905, first protection frame; 906, card slot; 907, second protection frame; 908, return spring; 909, clamping rod; 910, sealing plate; 911, first threaded rod; 912, connecting frame; 913, rotating cylinder; 914, telescopic sleeve rod; 915, second threaded rod; 916, pushing plate; 917, plug rod; 918, rubber piston; 919, plug pipe; 920, rubber suction cup; 10, second filter plate. Detailed implementation mode

[0043] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without making creative efforts fall within the scope of protection of the present invention.

[0044] Embodiment 1

[0045] As Figures 1 to 15As shown in the figure, this embodiment proposes a tumor photodynamic therapy device with dual laser wavelengths, including a protective housing 1. Inside the protective housing 1, a multi-stage cooling component 2 is installed. The multi-stage cooling component 2 includes a driving motor 201 and a heat conduction tube 209. The driving motor 201 is welded and fixed inside the protective housing 1. The output end of the driving motor 201 is connected to an output shaft 202. A first gear 203 is welded and fixed on the output shaft 202. A second gear 204 is meshed with the first gear 203. A third gear 205 is meshed with the second gear 204. A screw rod 206 is welded and fixed on the third gear 205. An insulation box 207 is welded and fixed inside the protective housing 1. A conveying cylinder 208 is welded and fixed inside the insulation box 207. One end of the heat conduction tube 209 is connected to the conveying cylinder 208, and the other end of the heat conduction tube 209 is connected to the top side end of the insulation box 207. A first filter plate 3 and a second filter plate 10 are welded and fixed on the protective housing 1. A fixed mesh plate 4 is welded and fixed inside the protective housing 1. A moisture removal mesh plate 5 is bolted and fixed inside the protective housing 1. A laser therapy instrument 6 is installed and fixed inside the protective housing 1. Two optical fibers 7 are connected to the laser therapy instrument 6. Two optical fiber heads 8 are connected to the two optical fibers 7 respectively. The laser wavelengths emitted by the two optical fiber heads 8 are 635nm and 660nm respectively. Since different photosensitizers have different activation efficiencies at different wavelengths, the optical fiber heads 8 with different laser wavelengths can be selected for use, and then the treatment effect can be optimized according to the characteristics of the selected photosensitizer. A multi-functional protection component 9 is installed on the optical fiber 7. Through the multi-stage cooling component 2, the primary high-efficiency cooling and secondary high-efficiency cooling of the laser therapy instrument 6 can be conveniently realized. The primary or secondary cooling treatment can be carried out according to the working state of the laser therapy instrument 6, which is energy-saving and environment-friendly. And under the action of the multi-functional protection component 9, not only can the optical fiber head 8 after work be conveniently and stably sealed and protected, but also the optical fiber head 8 can be conveniently and stably adsorbed and fixed at a suitable irradiation position, ensuring the convenience and stability of the subsequent laser irradiation treatment work, and increasing the use diversity and practicability of the treatment device.

[0046] Embodiment 2

[0047] As Figures 1 to 15 shown, based on the same concept as the above Embodiment 1, this embodiment also proposes a tumor photodynamic therapy device with dual laser wavelengths.

[0048] In this embodiment, the second gears 204 are symmetrically distributed on both sides of the first gear 203. The second gears 204 and the third gears 205 are in one-to-one correspondence. The heat insulation boxes 207 are symmetrically distributed on both sides inside the protective housing 1. The heat insulation boxes 207 are in one-to-one correspondence with the screw rods 206, the conveying cylinders 208, and the heat conduction tubes 209 respectively. The screw rods 206 are rotatably connected inside the conveying cylinders 208. The length of the screw rods 206 is greater than the length of the conveying cylinders 208. The side ends of the heat insulation boxes 207 are provided with refrigeration chips 210. By means of the first gear 203, the second gears 204 and the third gears 205 on both sides can be driven, and thus the screw rods 206 can be driven to rotate stably inside the conveying cylinders 208, so that the purified water cooled in the heat insulation boxes 207 can be driven to continuously circulate inside the heat conduction tubes 209. By using the heat exchange principle, the surrounding air can be quickly cooled, and thus the subsequent cooling efficiency and cooling effect can be effectively improved.

[0049] In this embodiment, a fixed pipe 211 is connected to the top of the heat insulation box 207. An electromagnetic valve is installed on the fixed pipe 211. A through groove 212 is formed through the heat conduction tube 209. A hydraulic rod 213 is fixedly installed on the top of the protective housing 1. The bottom end of the hydraulic rod 213 is fixedly connected to a connecting rod 214. A sliding rod 215 is welded and fixed on the bottom end surface of the connecting rod 214. The sliding rod 215 is slidably connected through the heat conduction tube 209. The hydraulic rod 213 is fixed in the middle of the connecting rod 214. The sliding rods 215 are symmetrically distributed on both sides of the bottom of the connecting rod 214. The bottom end of the sliding rod 215 is fixedly connected to a sealing block 216. The length and width of the sealing block 216 are respectively greater than the length and width of the through groove 212. The sealing block 216 is in fit with the inner wall of the heat conduction tube 209. The sealing block 216 is made of rubber material. By driving the hydraulic rod 213, the through groove 212 can be conveniently opened, so that the automatically conveying work of the cooled purified water can be carried out.

[0050] In this embodiment, a fixed plate 217 is welded and fixed on the heat conduction pipe 209, and a first guide groove 218 is opened in the fixed plate 217. A driven shaft 219 is welded and fixed on the second gear 204. An exhaust fan 220, a fixed rod 221 and a scraper rod 226 are welded and fixed on the driven shaft 219. A rotating ring 222 is welded and fixed on the fixed rod 221. A second guide groove 223 is opened on the rotating ring 222. A first sponge rod 224 is fixedly connected to the rotating ring 222, and a second sponge rod 225 is fixedly connected to the fixed rod 221. The output shaft 202 is rotatably connected to the fixed mesh plate 4, and the driven shaft 219 is rotatably connected to the first filter plate 3 and the fixed mesh plate 4. The spiral rod 206 is rotatably connected in the temperature isolation box 207 through a sealed bearing. The bottom end surface of the fixed plate 217 is in an arc shape, and the bottom end surface of the fixed plate 217 is connected to the rotating The outer wall of the moving ring 222 is fitted together, the second guide groove 223 and the first sponge rod 224 are evenly distributed on the rotating ring 222, the first sponge rod 224 is arc-shaped, the fixed rod 221 is evenly distributed on the driven shaft 219, the second sponge rod 225 is symmetrically distributed on both sides of the fixed rod 221, the second sponge rod 225 is fitted with the first sponge rod 224, the first guide groove 218 is connected with the through groove 212, the scraper rod 226 is fitted with the first filter plate 3, and the rotating ring 222 is fitted with the heat pipe 209. Under the continuous rotation of the rotating ring 222, the cooled clean water can be automatically and intermittently transported to each first sponge rod 224 and the second sponge rod 225. By absorbing heat through evaporation of water, the cooling effect of the surrounding air can be further improved, and the secondary high-efficiency cooling of the laser therapy device 6 can be achieved, further improving the cooling effect and cooling efficiency.

[0051] In this embodiment, the multifunctional protection component 9 includes a flexible cylinder 901 and a support plate 902. Both the flexible cylinder 901 and the support plate 902 are fixedly connected to the optical fiber 7. The support plate 902 is fixedly connected to the flexible cylinder 901. A sealing frame 903 and an adapter plate 904 are fixedly connected to the support plate 902. A first protection frame 905 is rotatably connected to the adapter plate 904. A card slot 906 is formed in the first protection frame 905. A second protection frame 907 is sleeved on the first protection frame 905. The first protection frames 905 are symmetrically distributed on both sides of the support plate 902. The first protection frames 905 and the second protection frames 907 are in one-to-one correspondence. The card slots 906 are equidistantly distributed on the first protection frame 905. A return spring 908 is welded and fixed to the second protection frame 907. A clamping rod 909 is welded and fixed to the return spring 908. The clamping rod 909 is slidably connected through the second protection frame 907. The end of the clamping rod 909 is snap-fitted into the card slot 906. A sealing plate 910 is fixedly connected to the second protection frame 907. Both the sealing plate 910 and the sealing frame 903 are made of rubber material. The sealing frame 903 is fitted to the second protection frame 907. By using the cooperation of the card slot 906 and the clamping rod 909, the working position of the rubber suction cup 920 can be conveniently adjusted according to the actual situation, increasing the practicability of the treatment device.

[0052] In this embodiment, a first threaded rod 911 and a rotating cylinder 913 are rotatably connected to the second protection frame 907. A connecting frame 912 is threadedly connected to the first threaded rod 911. The rotating cylinder 913 is slidably connected through the connecting frame 912. A telescopic sleeve rod 914 is slidably connected in a limited manner in the rotating cylinder 913. A second threaded rod 915 is welded and fixed to the telescopic sleeve rod 914. The second threaded rod 915 is rotatably connected in the connecting frame 912. A push plate 916 is threadedly connected to the second threaded rod 915. A plug rod 917 is fixedly connected to the push plate 916. A rubber piston 918 is fixedly connected to the plug rod 917. The rubber piston 918 is slidably connected in a plug tube 919. A rubber suction cup 920 is connected to the plug tube 919. The plug tube 919 is fixedly connected to the connecting frame 912. The first threaded rods 911 are symmetrically distributed on both sides of the connecting frame 912. The rotating cylinder 913 is connected to the central part of the connecting frame 912. The plug rods 917 are equidistantly distributed on the push plate 916. The plug rods 917 and the plug tubes 919 are in one-to-one correspondence through the rubber pistons 918. By fitting the second protection frames 907 on both sides together and adsorbing and fixing them through the rubber suction cup 920, a convenient and stable sealing and protection treatment can be carried out on the working light therapy head 8, avoiding the light therapy head 8 from being contaminated by the outside or damaged by accidental touch, increasing the use safety and stability of the treatment device; and when the light therapy head 8 starts to work, by rotating and separating the second protection frames 907 on both sides and also cooperating with the rubber suction cup 920, the light therapy head 8 can be conveniently and stably adsorbed and fixed at a suitable irradiation position, ensuring the convenience and stability of the subsequent laser irradiation treatment work.

[0053] It should be noted that the present invention is a tumor photodynamic therapy device with dual laser wavelengths. First, after the patient is injected with the photosensitizer and the laser treatment instrument 6 starts to work, the staff can rotate the rotating cylinder 913 on the second protective frames 907 on both sides in the forward direction. Under the rotation of the rotating cylinder 913, the telescopic sleeve rod 914 can drive the second threaded rod 915 to rotate stably, and can drive the push plate 916 connected by threads to move towards the plug tube 919, and then can drive the rubber pistons 918 on the respective plug rods 917 to move into the corresponding plug tube 919. At this time, the air in the plug tube 919 is pushed into the rubber suction cup 920, and the negative pressure inside the rubber suction cup 920 disappears. At this time, the rubber suction cups 920 at the connection frames 912 on both sides are separated from each other. Subsequently, the staff can rotate the first protective frames 905 and the second protective frames 907 on both sides to rotate and separate them;

[0054] After the first protective frame 905 and the second protective frame 907 are rotated by 90°, each plug tube 919 and the corresponding rubber suction cup 920 are parallel to the light therapy head 8. At this time, the staff can align the light therapy head 8 with the position where the patient needs laser irradiation treatment, and at the same time attach the rubber suction cup 920 around it. At this time, just rotate the rotating cylinder 913 in the reverse direction. The telescopic sleeve rod 914 drives the second threaded rod 915 to rotate, and the push plate 916 connected by threads can drive the rubber piston 918 on the plug rod 917 to move away from the rubber suction cup 920. Combined with the plug tube 919, the air inside the rubber suction cup 920 can be sucked. At this time, a negative pressure is formed inside the rubber suction cup 920, and the light therapy head 8 on the optical fiber 7 can be conveniently and stably adsorbed and fixed at the position where the patient needs laser irradiation treatment by cooperating with the flexible cylinder 901 and the support plate 902. Cooperating with the laser treatment instrument 6, laser irradiation can be carried out. When the photosensitizer absorbs the laser energy of a specific wavelength, it will change from the ground state to the excited state, and then react with the surrounding oxygen molecules to generate singlet oxygen and other reactive oxygen species. These reactive oxygen species have strong oxidation ability and can damage the membranes, proteins and DNA of tumor cells, thereby causing the death of tumor cells and achieving the purpose of treating tumors;

[0055] Before the rubber suction cup 920 and the light therapy head 8 start working, the staff can pull the latch 909 on the second protective frame 907 outwards to make it move out of the card slot 906. Then, the second protective frame 907 can be pulled to move on the first protective frame 905. After moving to the appropriate position, the latch 909 on the second protective frame 907 can be released. At this time, under the elastic action of the return spring 908, the latch 909 can be driven to engage in the adjacent card slot 906, completing the position adjustment and snap fixation of the second protective frame 907 on the first protective frame 905. By adjusting the second protective frame 907, the working position of the rubber suction cup 920 can be conveniently adjusted according to the actual situation. And the staff can rotate the first threaded rods 911 on both sides of the connecting frame 912 at the same time. Under the rotation of the first threaded rods 911, the connecting frame 912 connected by threads can be driven to move, and thus the support height of the light therapy head 8 can be conveniently adjusted according to the actual situation, increasing the diversity and practicality of the use of the treatment device.

[0056] After the light therapy head 8 finishes working, the above operations can be repeated. First, drive each rubber piston 918 to make the negative pressure inside the rubber suction cup 920 disappear and complete the separation. Then, the second protective frame 907 and the connecting frame 912 can be moved back to their original positions, and the two sides of the second protective frame 907 can be pushed to rotate and fit. At this time, drive each rubber piston 918 again. At this time, the rubber suction cups 920 at the two sides of the second protective frame 907 are attached to each other and adsorbed to complete the closing work of the two sides of the second protective frame 907. At this time, the second protective frame 907 combined with the first protective frame 905, the sealing frame 903 and the sealing plate 910 can conveniently complete the sealing protection work of the light therapy head 8.

[0057] During the working process of the laser therapy instrument 6, under the driving action of the driving motor 201, the output shaft 202 can drive the first gear 203 to rotate. Under the meshing driving action, the second gear 204 can be driven to rotate, and the second gear 204 drives the third gear 205 to rotate. During the rotation of the second gear 204, the exhaust fan 220 can be stably driven to rotate through the driven shaft 219. At this time, the outside air enters the device through the first filter plate 3 and is discharged through the second filter plate 10 to complete the air circulation. And during the air flow process, the third gear 205 can drive the screw rod 206 to stably rotate in the conveying cylinder 208, and then the purified water in the heat insulation box 207 can be conveyed into the heat conduction tube 209 and then conveyed back into the heat insulation box 207 through the heat conduction tube 209 to complete the circulation. Moreover, during the circulation process, continuous cooling treatment can be carried out through the refrigeration sheet 210. Therefore, during the circulation of the cooled purified water in the heat conduction tube 209, using the heat exchange principle, the surrounding air can be quickly cooled, and the cooled air can be conveyed to the laser therapy instrument 6 through the exhaust fan 220 to achieve primary high-efficiency cooling.

[0058] When the laser therapeutic apparatus 6 works for a long time, the hydraulic rod 213 can be driven. At this time, the hydraulic rod 213 can drive the sliding rod 215 to move upward through the connecting rod 214, and then can drive the sealing block 216 to move upward. At this time, the sealing block 216 disengages from the inner bottom end surface of the heat conduction tube 209 and fits with the inner top end surface of the heat conduction tube 209, which can close the chute of the sliding rod 215 and open the through groove 212. At this time, during the rotation of the exhaust fan 220, the rotating ring 222 on the fixed rod 221 can be stably driven to rotate through the driven shaft 219. When the second diversion groove 223 on the rotating ring 222 moves to align with the first diversion groove 218 on the fixed plate 217, the cooled purified water can be automatically transported into the first sponge rod 224 and the second sponge rod 225 through the through groove 212, the first diversion groove 218 and the second diversion groove 223. By using the evaporation heat absorption of water, the cooling effect of the surrounding air can be further improved, realizing the secondary high-efficiency cooling of the laser therapeutic apparatus 6. And under the action of the moisture removal mesh plate 5, the moisture in the air is prevented from entering the device and affecting the normal operation of the device;

[0059] And under the action of the first filter plate 3, the outside air can be filtered at the air inlet. Moreover, during the operation of the exhaust fan 220, the scraping rod 226 can be driven to rotate automatically through the driven shaft 219, and then the dust and impurities filtered on the first filter plate 3 can be automatically scraped and cleaned, ensuring the stability of the first filter plate 3 during long-term operation and preventing the first filter plate 3 from being blocked and affecting the ventilation work.

[0060] The above are only the preferred embodiments of the present invention and are not intended to limit the present invention. Any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention shall be included in the protection scope of the present invention.

Claims

1. A tumor photodynamic therapy device with dual laser wavelengths, characterized in that: The invention comprises a protective shell (1), wherein a multi-stage cooling component (2) is installed in the protective shell (1), wherein the multi-stage cooling component (2) comprises a driving motor (201) and a heat conducting pipe (209), wherein the driving motor (201) is welded and fixed in the protective shell (1), wherein an output end of the driving motor (201) is connected to an output shaft (202), wherein a first gear (203) is welded and fixed to the output shaft (202), wherein a second gear (204) is meshedly connected to the first gear (203), wherein a third gear (205) is meshedly connected to the second gear (204), wherein a spiral rod (206) is welded and fixed to the third gear (205), and wherein a temperature isolation box (207) is welded and fixed in the protective shell (1). A conveying cylinder (208) is welded and fixed inside the thermal insulation box (207), one end of the heat-conducting pipe (209) is connected to the conveying cylinder (208), and the other end of the heat-conducting pipe (209) is connected to the top side of the thermal insulation box (207). A first filter plate (3) and a second filter plate (10) are welded and fixed on the protective shell (1). A fixed mesh plate (4) is welded and fixed inside the protective shell (1). A dehumidification mesh plate (5) is bolted inside the protective shell (1). A laser therapy device (6) is installed and fixed inside the protective shell (1). An optical fiber (7) is connected to the laser therapy device (6), a phototherapy head (8) is connected to the optical fiber (7), and a multifunctional protective component (9) is installed on the optical fiber (7).

2. The tumor photodynamic therapy device with dual laser wavelengths according to claim 1, characterized in that: The second gear (204) is symmetrically distributed on both sides of the first gear (203), and the second gear (204) corresponds to the third gear (205) one by one. The thermal insulation box (207) is symmetrically distributed on both sides inside the protective shell (1), and the thermal insulation box (207) corresponds to the screw rod (206), the conveying cylinder (208) and the heat conducting pipe (209) one by one respectively. The screw rod (206) is rotatably connected in the conveying cylinder (208), and the length of the screw rod (206) is greater than the length of the conveying cylinder (208).

3. The tumor photodynamic therapy device with dual laser wavelengths according to claim 2, characterized in that: A refrigeration plate (210) is installed on the side end of the thermal insulation box (207), a fixed tube (211) is connected to the top of the thermal insulation box (207), a through groove (212) is opened through the heat conduction tube (209), a hydraulic rod (213) is fixedly installed on the top of the protective shell (1), a connecting rod (214) is fixedly connected to the bottom end of the hydraulic rod (213), a sliding rod (215) is welded and fixed on the bottom end surface of the connecting rod (214), and the sliding rod (215) passes through and is slidably connected in the heat conduction tube (209).

4. The tumor photodynamic therapy device with dual laser wavelengths according to claim 3 is characterized in that: The hydraulic rod (213) is fixed at the middle part of the connecting rod (214), and the sliding rod (215) is symmetrically distributed on both sides of the bottom of the connecting rod (214). The bottom end of the sliding rod (215) is fixedly connected with a sealing block (216), and the length and width of the sealing block (216) are respectively greater than the length and width of the through groove (212), and the sealing block (216) is in contact with the inner wall of the heat conduction pipe (209).

5. The tumor photodynamic therapy device with dual laser wavelengths according to claim 4, characterized in that: A fixing plate (217) is welded and fixed on the heat conduction pipe (209), a first guide groove (218) is penetrated in the fixing plate (217), a driven shaft (219) is welded and fixed on the second gear (204), an exhaust fan (220), a fixing rod (221) and a scraper rod (226) are welded and fixed on the driven shaft (219), a rotating ring (222) is welded and fixed on the fixing rod (221), a second guide groove (223) is penetrated in the rotating ring (222), a first sponge rod (224) is fixedly connected to the rotating ring (222), and a second sponge rod (225) is fixedly connected to the fixing rod (221).

6. The tumor photodynamic therapy device with dual laser wavelengths according to claim 5, characterized in that: The bottom end surface of the fixed plate (217) is in an arc shape, and the bottom end surface of the fixed plate (217) is in contact with the outer wall of the rotating ring (222); the second guide groove (223) and the first sponge rod (224) are evenly distributed on the rotating ring (222); the first sponge rod (224) is in an arc shape; the fixed rod (221) is evenly distributed on the driven shaft (219); and the second sponge rod (225) is symmetrically distributed on both sides of the fixed rod (221).

7. The tumor photodynamic therapy device with dual laser wavelengths according to claim 1, characterized in that: The multifunctional protective assembly (9) comprises a flexible tube (901) and a support plate (902), wherein the flexible tube (901) and the support plate (902) are both fixedly connected to the optical fiber (7), the support plate (902) is fixedly connected to a sealing frame (903) and a connecting plate (904), the connecting plate (904) is rotatably connected to a first protective frame (905), a card slot (906) is provided on the first protective frame (905), a second protective frame (907) is sleeved on the first protective frame (905), the first protective frame (905) is symmetrically distributed on both sides of the support plate (902), the first protective frame (905) corresponds to the second protective frame (907) one by one, and the card slots (906) are equidistantly distributed on the first protective frame (905).

8. The tumor photodynamic therapy device with dual laser wavelengths according to claim 7, characterized in that: A reset spring (908) is welded and fixed on the second protective frame (907), and a clamping rod (909) is welded and fixed on the reset spring (908). The clamping rod (909) is slidably connected to the second protective frame (907), and the end of the clamping rod (909) is snap-connected in the clamping groove (906). A sealing plate (910) is fixedly connected to the second protective frame (907), and the sealing plate (910) and the sealing frame (903) are both made of rubber material.

9. The tumor photodynamic therapy device with dual laser wavelengths according to claim 8, characterized in that: The second protection frame (907) is rotatably connected to a first threaded rod (911) and a rotating cylinder (913); the first threaded rod (911) is threadedly connected to a connecting frame (912); the rotating cylinder (913) is slidably connected to the connecting frame (912); a telescopic sleeve rod (914) is limitedly slidably connected inside the rotating cylinder (913); a second threaded rod (915) is welded and fixed to the telescopic sleeve rod (914); the second threaded rod (915) The second threaded rod (915) is rotatably connected in a connection frame (912); a push plate (916) is threadedly connected to the push plate (916); a plug rod (917) is fixedly connected to the plug rod (917); a rubber piston (918) is fixedly connected to the plug rod (917); the rubber piston (918) is slidably connected in a plug tube (919); a rubber suction cup (920) is connected to the plug tube (919); and the plug tube (919) is fixedly connected in the connection frame (912).

10. The tumor photodynamic therapy device with dual laser wavelengths according to claim 9, characterized in that: The first threaded rod (911) is symmetrically distributed on both sides of the connecting frame (912), the rotating cylinder (913) is connected to the central part of the connecting frame (912), the plug rod (917) is equidistantly distributed on the push plate (916), and the plug rod (917) corresponds one-to-one with the plug tube (919) through the rubber piston (918).

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