Continuous high-selectivity enrichment equipment and method for new psychoactive pollutants in offshore surface seawater

Abstract

The invention relates to continuous high-selectivity enrichment equipment and method for new psychoactive pollutants in offshore surface seawater, and the equipment comprises a collection device for collecting seawater, an enrichment device for adsorbing the psychoactive pollutants in the seawater and discharging wastewater, and a floating body device for bearing the equipment, the sampling device comprises a liquid inlet pipe communicated with the enriching device, a filtering device used for filtering offshore surface seawater, and a timing liquid pump device used for controlling the flow speed and time of the seawater flowing into the enriching device in the collecting device. The invention solves the technical problem of high sample preservation and transportation cost in the process of detecting and analyzing the new psychoactive pollutants in the prior art. According to the invention, in-situ enrichment of new psychoactive pollutants in seawater is realized, and the sample amount and the sample transportation cost are greatly reduced.

Description

Technical Field

[0001] The present invention belongs to the technical field of marine environmental monitoring. Specifically, it relates to a device for extracting and enriching new psychoactive substances in seawater and a method for enriching new psychoactive substances based on the enrichment device. Background Art

[0002] Psychoactive substances refer to substances that affect psychological processes such as thinking, emotion, will, and behavior after being used by the human body, including central nervous system depressants, central nervous system stimulants, hallucinogens, opioid substances, and cannabis, etc. The main characteristics of these drugs include: psychoactive substances usually have different pharmacological effects from traditional drugs by fine-tuning the molecular structure; since they have not been clearly listed in regulations, these substances are often used by abusers to evade legal supervision; due to the limited research on these drugs, their long-term harmfulness and toxicity have not been fully understood.

[0003] Currently, due to limitations of factors such as devices and electricity, traditional sample pretreatment techniques mostly adopt the steps of on-site sampling → encapsulation → transportation → laboratory determination. Since processes such as encapsulation, transportation, and storage are required before sample processing, the workload is large, the real-time performance is poor, and continuous data cannot be provided; moreover, during the sampling, storage, and transportation processes, "contamination" and "transformation" of the samples may occur, resulting in inaccurate detection results. At the same time, since the sample processing time is relatively long and mostly needs to be completed in the laboratory, detection data cannot be obtained quickly.

[0004] In addition, since the concentration of psychoactive substances in the surface seawater of the coastal sea is relatively low, generally at the ng / L level and is greatly affected by the complex matrix of seawater. Therefore, before instrument detection, seawater samples need to be enriched and purified. Different types of molecularly imprinted materials can be selected in the pretreatment stage for detecting different psychoactive substances. For example, for the detection of amphetamines, molecularly imprinted materials with 3,4-methylenedioxyphenethylamine as the template can be used; for the detection of codeine, molecularly imprinted materials with methacrylic acid - ethylene glycol dimethacrylate as the template can be used, and so on. Therefore, there is an urgent need to find a method for continuously and highly selectively enriching psychoactive substances in the surface seawater of the coastal sea to solve the above problems. Summary of the Invention

[0005] In order to solve the problems of long processing time, inability to complete on-site, potential pollution and property change during water sample transportation in the existing seawater pollutant extraction methods, the present invention proposes a device and method for continuously and highly selectively enriching new psychoactive pollutants in the surface seawater of the coastal sea, which can rapidly, efficiently, and easily enrich organic pollutants in seawater, effectively reducing the transportation and storage costs, and improving the throughput and effectiveness of sample processing.

[0006] A continuous enrichment device for psychoactive new pollutants in offshore surface seawater, comprising: a collection device for collecting seawater, an enrichment device for adsorbing psychoactive pollutants in seawater and discharging wastewater, and a floating device for carrying the device;

[0007] The collection device is an in-situ active sampling device, including a liquid inlet pipe connected to the enrichment device, a filtering device for filtering offshore surface seawater, and a timing liquid pump device for controlling the flow rate and time of seawater flowing into the enrichment device.

[0008] Further, the timing liquid pump device is connected to the filtering device, the enrichment device is communicated with the filtering device, and all devices are located on the floating material.

[0009] Further, the filtering device includes a filter net device and a filter device. The filter net device is used for filtering larger objects, and the filter device is used for filtering fine objects; the filter device includes a filtering component containing a filter membrane.

[0010] Further, a filter net device is provided at the water inlet of the liquid inlet pipe, and the other end is communicated with the enrichment device; the filter device is located between the timing liquid pump device and the enrichment device.

[0011] Further, the enrichment device includes an enrichment container containing a molecularly imprinted membrane. The liquid inlet pipe is communicated with the enrichment container, and an outlet pipe communicated with the enrichment container. The liquid inlet pipe is communicated with the enrichment container, and the outlet pipe of the enrichment container is communicated with the seawater.

[0012] Further, the molecularly imprinted membrane in the enrichment container of the enrichment device is prepared with a molecularly imprinted material as the adsorption material and a filter membrane as the membrane substrate. Suitable filter membranes and molecularly imprinted materials can be selected according to the physical and chemical properties of the target substance. Filter membranes with different substrates can be selected for different target substances, including polysulfone, polytetrafluoroethylene, polyvinylidene fluoride, mixed cellulose, and nylon filter membranes, with a pore size range of 0.45μm - 1μm. Different types of molecularly imprinted materials can be selected for detecting different psychoactive substances. For example, for the detection of amphetamines, a molecularly imprinted material with 3,4-methylenedioxyphenethylamine as the template can be used; for the detection of codeine, a molecularly imprinted material with methacrylic acid - ethylene glycol dimethacrylate as the template can be used, etc. Preferably, the molecularly imprinted membrane can be activated before use.

[0013] Further, the filter device includes a filtering component containing a filter membrane. Filter membranes such as polyvinylidene fluoride, polyethersulfone, ceramic membrane, polytetrafluoroethylene, and polypropylene can be selected, with a pore size range of 0.1μm - 10μm.

[0014] Further, a flowmeter assembly for monitoring the flow rate is also provided between the collection device and the enrichment device.

[0015] Further, all of the devices are located on the floating device.

[0016] Further, the timing liquid pump device includes a liquid pump and a timer. The liquid pump provides power for the collection device. The timer is connected to the liquid pump, and the liquid pump is connected to the filtering device.

[0017] Further, the device is also provided with an anchor for fixing the device, and the device is fixed to the sea surface through the anchor.

[0018] Based on the above enrichment device for new psychoactive substances in seawater, the present invention also proposes a method for enriching new psychoactive substances designed by using the enrichment device, including the following steps:

[0019] Adopt the continuous enrichment device for psychoactive substances in the offshore surface seawater as described above, and place the continuous enrichment device for psychoactive substances in the offshore surface seawater at a position around the offshore surface sampling point; extend the water inlet of the collection device into the position of the offshore surface seawater sampling point to perform the operation of collecting seawater; use the timer to measure the sampling time, and stop collecting when the time reaches the preset time; turn on the liquid pump to make the water sample enter the enrichment device at a uniform flow rate from the metering device, and the enrichment device adsorbs the psychoactive substances in the water sample; the enriched wastewater is discharged from the liquid outlet pipe of the enrichment container; after the water sample is enriched, remove the enrichment device, remove the molecularly imprinted membrane, and send it to the laboratory for detection.

[0020] Further, when the enrichment device is removed, remove the molecularly imprinted membrane and place it in the sample box for storage.

[0021] Compared with the prior art, the advantages and positive effects of the present invention are as follows: The present invention specifically designs an enrichment device for new psychoactive substances in seawater. Different molecularly imprinted materials and filter membranes can be selected according to the types and properties of the target substances. The molecularly imprinted materials are uniformly compounded on the filter membranes to adsorb the target substances in seawater, which is particularly suitable for the enrichment of various new psychoactive substances in large-volume water samples. The present invention solves the technical problem of high sample storage and transportation costs in the detection and analysis of new psychoactive pollutants in the prior art. The present invention realizes the in-situ enrichment of new psychoactive pollutants in seawater, greatly reducing the sample volume and the transportation cost of the samples. Compared with the traditional manual sample pretreatment method, this device can achieve better accuracy and reproducibility, significantly improving the pretreatment efficiency. At the same time, it greatly reduces the chance for experimental personnel to contact the target pollutants and organic solvents, thereby making the pretreatment process safer. Moreover, it avoids potential pollution and changes during the water sample transportation process, effectively reducing the transportation and storage costs and improving the accuracy of the analysis results. The enrichment device of the present invention has the characteristics of high efficiency, high stability, easy to carry, and easy to operate, saving both time and cost, and can provide a reliable monitoring and prevention means for environmental protection and early warning of sudden disasters. BRIEF DESCRIPTION OF THE DRAWINGS

[0022] Figure 1 It is a structural diagram of a continuous sampling and enrichment device.

[0023] Figure 2 It is a schematic diagram of a continuous sampling and enrichment device system.

[0024] In the figure: 1, anchor; 2, floating device; 3, filter net; 4, liquid pump; 5, timer; 6, lithium battery; 7, filter; 8, flowmeter; 9, enrichment container. DETAILED DESCRIPTION OF THE EMBODIMENTS

[0025] Next, the technical solutions in the embodiments of the present invention will be clearly and completely described in conjunction with the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts shall fall within the protection scope of the present invention.

[0026] Such as Figure 1-2As shown in the figure, the present invention provides a continuous sampling and enrichment device for psychoactive substances in offshore surface seawater, including a sampling device for collecting seawater, an enrichment device 9 for adsorbing compounds in seawater and discharging wastewater, an anchor 1 for fixing the device, and a floating device 2 for carrying the device. The floating device 2 is connected to the anchor 1; the sampling device includes a liquid inlet pipe connected to the enrichment device 9, a filtering device for filtering offshore surface seawater, and a timing liquid pump device for measuring seawater; the filtering device includes a filter screen 3 and a filter 7; the timing liquid pump device includes a timer 5 and a liquid pump 4. One end of the timer 5 is connected to the liquid pump 4, the other end of the timer 5 is connected to a lithium battery 6, the liquid pump 4 is connected to the liquid inlet pipe for collecting seawater, the water inlet of the liquid inlet pipe is provided with a filter screen 3, and the other end is connected to the enrichment device 9; the filter 7 is located between the timing liquid pump device and the enrichment device 9 and is connected to the liquid pump 4; a flowmeter 8 for observing the flow rate is also provided between the sampling device and the enrichment device 9. One end of the flowmeter 8 is connected to the filter 7, and the other end of the flowmeter 8 is connected to the enrichment device 9; the filter 7 includes a filtering component containing a filter membrane; the enrichment device 9 includes an enrichment container containing a molecularly imprinted membrane. The liquid inlet pipe is connected to the enrichment container, and the liquid outlet pipe of the enrichment container is connected to the seawater.

[0027] The present invention provides a continuous sampling and enrichment method for psychoactive substances in offshore surface seawater. The above-mentioned continuous sampling and enrichment device for psychoactive substances in seawater is adopted, and the continuous sampling and enrichment device for psychoactive substances in seawater is placed at a position around the seawater sampling point; the seawater is collected by extending the water inlet of the sampling device to the position of the seawater sampling point; the sampling time is measured by using the timer, and when the time reaches the preset time, the collection is stopped; the liquid pump is turned on to make the water sample enter the enrichment device 9 at a uniform flow rate from the metering device. The enrichment device 9 adsorbs the psychoactive substances in the water sample; the enriched wastewater is discharged from the enrichment device 9; after the water sample is enriched, the enrichment device is removed, the molecularly imprinted membrane is removed, and sent to the laboratory for detection; when the enrichment device 9 is removed, the molecularly imprinted membrane is removed and placed in a sample box for storage. After the water sample is enriched, the enrichment device 9 is removed, the molecularly imprinted membrane is removed, and sent to the laboratory for detection; when the enrichment device 9 is removed, the molecularly imprinted membrane is removed and placed in a sample box for storage.

[0028] The present invention connects a seawater sampling device, a liquid pump and an enrichment device to simultaneously achieve quantitative water sampling and in-situ enrichment of psychoactive substances at the sampling site. This not only greatly reduces the sample volume and facilitates the calculation of the concentration of psychoactive substances, but also avoids secondary contamination of the sample during transportation and repeated measurement. The water inlet of the seawater sampling device is equipped with a filter screen and a filter, which can filter out larger particulate matters and prevent blockage of subsequent pipelines and enrichment devices. The aperture range of the filter screen 3 is 0.5 mm - 1 mm. The filter 7 can be selected from filter membranes such as polyvinylidene fluoride, polyethersulfone, ceramic membrane, polytetrafluoroethylene and polypropylene, and the filter membrane with an aperture range of 0.1 μm - 10 μm is mainly used to separate suspended solids in seawater from seawater, and different types of filter membranes can be selected according to the chemical properties of the target substances. The molecularly imprinted membrane of the enrichment device can be selected according to the chemical properties of different target substances.

[0029] The present invention enriches psychoactive substances in seawater through an enrichment device set at an offshore seawater sampling point. It only needs to transport the molecularly imprinted membrane enriched with psychoactive substances, thus solving the technical problem of high sample storage and transportation costs in the detection and analysis process of psychoactive substances in the prior art. The present invention realizes in-situ enrichment of psychoactive substances in offshore seawater, greatly reducing the sample volume and the transportation cost of the sample. Moreover, the enrichment device can be paired with commercially available filter membranes, and the molecularly imprinted material can be selected according to the sample characteristics, with high flexibility, and can be applied to on-line sampling and enrichment of various psychoactive substances.

[0030] The parts not involved in the present invention are the same as or can be implemented by the prior art. The above description is only a preferred embodiment of the present invention, and does not impose any form of limitation on the present invention. Although the present invention has been disclosed above with a preferred embodiment, it is not intended to limit the present invention. Any person skilled in the art, without departing from the technical solution of the present invention, can make some changes or modifications to equivalent embodiments by using the above-disclosed technical content. However, as long as it does not depart from the technical solution of the present invention, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention still fall within the scope of the technical solution of the present invention.

Claims

1. A continuous sampling and enrichment device for psychoactive substances in offshore surface seawater, characterized in that: include: a collection device for collecting seawater, an enrichment device for absorbing psychoactive pollutants in seawater and discharging wastewater, and a floating device for carrying equipment; The collection device comprises a liquid inlet pipe connected to the enrichment device, a filtering device for filtering offshore surface seawater, and a timing liquid pump device for controlling the flow rate and time of the seawater in the collection device.

2. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 1 is characterized in that: The enrichment device comprises an enrichment container containing a molecular imprinting membrane, a liquid inlet pipe is connected to the enrichment container, and a liquid outlet pipe of the enrichment container is connected to seawater.

3. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 1 is characterized in that: The filtering device comprises a filtering screen device and a filter device.

4. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 3 is characterized in that: The filter device includes a filter assembly including a filter membrane.

5. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 2 is characterized in that: A flow meter assembly is also provided between the collection device and the enrichment device.

6. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 2 is characterized in that: The molecular imprinting membrane in the enrichment container of the enrichment device is prepared with molecular imprinting material as adsorption material and filter membrane as membrane substrate. The filter membrane and molecular imprinting material can be selected according to the target object.

7. The continuous sampling and enrichment device for psychoactive substances in offshore surface seawater according to claim 3 is characterized in that: The water inlet of the liquid inlet pipe is provided with a filter device, and the other end is connected with the enrichment device; the filter device is located between the timing liquid pump device and the enrichment device.

8. The equipment for continuous sampling and enrichment of psychoactive substances in seawater according to claim 1, characterized in that: The timing liquid pump device comprises a liquid pump and a timer, the liquid pump provides power for the collection device, the timer is connected to the liquid pump, and the liquid pump is connected to the filtering device.

9. A method for continuous sampling and enrichment of psychoactive substances in offshore surface seawater, characterized in that: The steps include: The continuous sampling and enrichment device for psychoactive substances in seawater as claimed in any one of claims 1 to 8 is used, and the continuous sampling and enrichment device for psychoactive substances in seawater is placed at a position around a seawater sampling point; the water inlet of the collection device is extended into the position of the seawater sampling point to collect seawater; The sampling time is measured by a timer, and when the time reaches a preset time, the sampling is stopped; the liquid pump is turned on to allow the water sample to flow from the metering device into the enrichment device at a uniform flow rate, and the enrichment device adsorbs the psychoactive substances in the water sample; The enriched wastewater is discharged from the enrichment device.

10. The method for continuous sampling and enrichment of psychoactive substances in offshore surface seawater according to claim 9, characterized in that: After the water sample is enriched, the enrichment device is removed, the molecular imprinting membrane is removed, and the samples are sent to the laboratory for testing. When the enrichment device is removed, the molecular imprinting membrane is removed and stored in a sample box.

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