Pressure detection method and device, computer equipment and storage medium

Abstract

The invention relates to the field of pressure detection, in particular to a pressure detection method and device, computer equipment and a storage medium. The method comprises the following steps: when the cell preparation equipment is not provided with pipeline consumables, acquiring an initial pressure value acquired by a pressure acquisition device; when the cell preparation equipment is provided with the pipeline consumables and the cell preparation equipment is in a non-starting state, acquiring an empty pipe pressure value in the pipeline consumables collected by a pressure collection device; after it is determined that the airtightness of the pipeline consumables meets the airtightness requirement according to the initial pressure value and the blank pipe pressure value, if the cell preparation equipment enters a working state, the working pressure value in the pipeline consumables is collected regularly through a pressure collection device; and determining a pressure detection result of the cell preparation equipment according to the working pressure value. The invention also discloses a method. Through dual-pressure detection on the pipeline consumables, good dual-airtightness of the pipeline consumables is ensured, so that waste of materials and labor cost is avoided.

Description

Technical Field

[0001] The present invention relates to the field of pressure detection, and particularly to a pressure detection method, device, computer device and storage medium. Background Art

[0002] With the rise of the cell therapy industry, the demand for cell preparation equipment is increasing. Due to the requirement of a sterile environment for cell preparation, there are high requirements for the airtightness of the disposable pipeline consumables of the cell preparation equipment and the airtightness during the cell preparation process.

[0003] In the existing cell preparation equipment, when loading the disposable pipeline consumables into the cell preparation equipment, they are often directly used without detecting the airtightness of the pipeline consumables and the airtightness during the working process of the cell preparation equipment, which makes it easy for the cell preparation work to fail due to poor airtightness of the pipeline consumables or during the working process of the cell preparation equipment, resulting in waste of materials and labor costs.

[0004] Therefore, there is an urgent need for a pressure detection method to detect the airtightness of the disposable pipeline consumables of the cell preparation equipment and the airtightness during the working process of the cell preparation equipment, so as to ensure that the airtightness of the pipeline consumables of the cell preparation equipment and the airtightness during the working process of the cell preparation equipment meet the requirements. Summary of the Invention

[0005] Based on this, it is necessary to provide a pressure detection method, device, computer device and storage medium for the above technical problems, so as to solve the problem in the prior art that the cell preparation work is easily failed due to poor airtightness of the pipeline consumables or during the working process of the cell preparation equipment, resulting in waste of materials and labor costs.

[0006] A pressure detection method includes:

[0007] When the pipeline consumables are not installed in the cell preparation equipment, obtaining an initial pressure value collected by a pressure acquisition device;

[0008] When the pipeline consumables are installed in the cell preparation equipment and the cell preparation equipment is in an unstarted state, obtaining an empty pipe pressure value in the pipeline consumables collected by the pressure acquisition device;

[0009] After determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty pipe pressure value, if the cell preparation equipment enters the working state, regularly collecting a working pressure value in the pipeline consumables by the pressure acquisition device;

[0010] Determining a pressure detection result of the cell preparation equipment according to the working pressure value.

[0011] A pressure detection device includes:

[0012] An initial pressure value module, configured to obtain an initial pressure value collected by a pressure acquisition device when no pipeline consumables are installed in the cell preparation device;

[0013] An empty tube pressure value module, configured to obtain an empty tube pressure value in the pipeline consumables collected by the pressure acquisition device when the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state;

[0014] A working pressure value module, configured to, after determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty tube pressure value, if the cell preparation device enters a working state, regularly collect a working pressure value in the pipeline consumables through the pressure acquisition device;

[0015] A detection result module, configured to determine a pressure detection result of the cell preparation device according to the working pressure value.

[0016] A cell preparation device, characterized by comprising a controller, a pressure detection device, pipeline consumables, and a centrifuge container having an air-permeable membrane, wherein the pipeline consumables are communicated with the centrifuge container; the pipeline consumables are detachably clamped and installed on the pressure detection device; the controller is connected to the pressure detection device, and the controller is configured to execute the above-mentioned pressure detection method.

[0017] One or more readable storage media storing computer-readable instructions, which, when executed by one or more processors, cause the one or more processors to execute the pressure detection method as described above.

[0018] The above-mentioned pressure detection method, device, computer device, and storage medium obtain an initial pressure value collected by a pressure acquisition device when no pipeline consumables are installed in the cell preparation device; obtain an empty tube pressure value in the pipeline consumables collected by the pressure acquisition device when the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state; after determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty tube pressure value, if the cell preparation device enters a working state, regularly collect a working pressure value in the pipeline consumables through the pressure acquisition device; determine a pressure detection result of the cell preparation device according to the working pressure value. In the present invention, by using the initial pressure value and the empty tube pressure value, it is possible to judge whether the airtightness of the pipeline consumables meets the airtightness requirements, accurately detect the airtightness of the pipeline consumables, and ensure good airtightness of the pipeline consumables. Furthermore, based on the pipeline consumables with good airtightness, a working pressure value when the cell preparation device is in a working state is obtained. Through double pressure detection of the pipeline consumables, it is ensured that the double airtightness of the pipeline consumables is good, thereby avoiding waste of material and labor costs. Brief Description of the Drawings

[0019] To more clearly illustrate the technical solutions of the embodiments of the present invention, the following will briefly introduce the drawings required for the description of the embodiments of the present invention. Obviously, the drawings in the following description are only some embodiments of the present invention. For those of ordinary skill in the art, without creative efforts, other drawings can be obtained based on these drawings.

[0020] Figure 1 It is a schematic diagram of an application environment of a pressure detection method in an embodiment of the present invention;

[0021] Figure 2 It is a schematic flowchart of a pressure detection method in an embodiment of the present invention;

[0022] Figure 3 It is a schematic structural diagram of a pressure detection device in an embodiment of the present invention;

[0023] Figure 4 It is a schematic diagram of a computer device in an embodiment of the present invention. Detailed Embodiments

[0024] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the drawings in the embodiments of the present invention. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention. All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts fall within the scope of protection of the present invention.

[0025] The pressure detection method provided in this embodiment can be applied to an application environment such as Figure 1 where the client communicates with the server. Among them, the client includes, but is not limited to, various personal computers, laptop computers, smart phones, tablet computers, and portable wearable devices. The server can be implemented by an independent server or a server cluster composed of multiple servers.

[0026] In one embodiment, as Figure 2 shown, a pressure detection method is provided. Taking the method applied to the Figure 1 server in as an example for description, it includes the following steps:

[0027] S10. When the pipeline consumables are not installed in the cell preparation device, obtain the initial pressure value collected by the pressure acquisition device.

[0028] It can be understood that the cell preparation device refers to a device for culturing and making cells. The pipeline consumables refer to the pipelines used to connect various preparation equipment in the cell preparation device. The initial pressure value refers to the pressure value when the pressure acquisition device is at atmospheric pressure.

[0029] Preferably, the cell preparation device includes a controller, a pressure detection device, pipeline consumables, and a centrifuge container with an air-permeable membrane. Among them, the pipeline consumables are connected to the centrifuge container, the pipeline consumables are detachably clamped and installed on the pressure detection device, and the controller is connected to the pressure detection device. Understandably, when there is an abnormal high pressure of the fluid in the pipeline consumables at the inlet end of the centrifuge, since the fluid releases pressure through the air-permeable membrane of the centrifuge, therefore, the fluid flowing out from the outlet end of the centrifuge will not have an abnormal high pressure. That is to say, due to the existence of the air-permeable membrane of the centrifuge, the pressure values at the outlet end and the inlet end of the centrifuge are independent of each other. Therefore, pressure detection devices need to be provided at both ends of the centrifuge.

[0030] Preferably, the pressure detection device includes a first pressure device arranged at the outlet end of the centrifuge container and a second pressure device arranged at the inlet end of the centrifuge container. The pipeline consumables include a first pipeline connecting the outlet end of the centrifuge container and clamped on the first pressure device, and a second pipeline connecting the inlet end of the centrifuge container and clamped on the second pressure device. Among them, the first pressure device is used to measure the pressure value at the outlet end of the centrifuge container. The second pressure device is used to measure the pressure value at the inlet end of the centrifuge container. Both the first pipeline and the second pipeline are used for guiding the flow. By providing pressure detection devices at both the outlet end and the inlet end of the centrifuge container, the position of the pipeline consumables with abnormal pressure can be quickly and accurately located.

[0031] S20. When the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state, obtain the empty pipe pressure value in the pipeline consumables collected by the pressure acquisition device.

[0032] Understandably, the empty pipe pressure value refers to the pressure value when the pipeline consumables are in an empty pipe state. Specifically, after obtaining the initial pressure value collected by the pressure acquisition device, all the pipeline consumables in the cell preparation device are installed. When all the pipeline consumables are installed and the cell preparation device is not started, the pressure value when the pipeline consumables are in an empty pipe state is collected by the pressure acquisition device.

[0033] Preferably, the empty pipe pressure value includes the first empty pipe pressure value of the first pipeline collected by the first pressure device and the second empty pipe pressure value of the second pipeline collected by the second pressure device. Among them, the first empty pipe pressure value is the pressure value when the first pipeline collected by the first pressure device is in an empty pipe state. Similarly, the second empty pipe pressure value is the pressure value when the second pipeline collected by the second pressure device is in an empty pipe state.

[0034] S30. After determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty pipe pressure value, if the cell preparation device enters the working state, the working pressure value in the pipeline consumables is periodically collected by the pressure acquisition device.

[0035] Understandably, the airtightness requirement refers to an index used to judge whether the airtightness of the pipeline consumables is good. The working state refers to the state in which the cell preparation device is preparing and culturing cells. The working pressure value refers to the pressure value in the pipeline consumables collected by the pressure acquisition device when the cell preparation device enters the working state.

[0036] Preferably, the working pressure value includes the first working pressure value in the pipeline consumables collected by the first pressure device after the cell preparation device enters the working state, and the second working pressure value in the pipeline consumables collected by the second pressure device after the cell preparation device enters the working state.

[0037] Preferably, if it is determined that the airtightness of the pipeline consumables does not meet the airtightness requirements according to the initial pressure value and the empty pipe pressure value, it indicates that there is a pressure difference between the internal pressure of the pipeline consumables and the atmospheric pressure. Therefore, it can be determined that there is a defect in the airtightness of the pipeline consumables. The installed pipeline consumables can be disassembled and reinstalled, and then steps S10 - S30 can be continued to ensure good airtightness of the pipeline consumables after installation.

[0038] Optionally, in step S30, that is, the working pressure value in the pipeline consumables is periodically collected by the pressure acquisition device, includes:

[0039] S301. Periodically collect the instantaneous pressure value of the pipeline consumables by the pressure acquisition device;

[0040] S302. Perform an averaging process on all the instantaneous pressure values collected within a preset duration to obtain the average pressure value of the pipeline consumables within the preset duration, and record the average pressure value as the working pressure value.

[0041] Understandably, timing refers to the preset pressure value acquisition time. The instantaneous pressure value refers to the pressure value of the pipeline consumables at a certain moment when the cell preparation device is in the working state. The preset duration refers to the preset acquisition duration. For example, if the pipeline consumables are pressure - detected four times per second (about 1 instantaneous pressure value is collected every 0.25 seconds), 4 instantaneous pressure values can be measured. Among them, the preset duration is 1 second, and the average pressure value is the average of the 4 instantaneous pressure values. Determining the working pressure value of the pipeline consumables through multiple instantaneous pressure values can improve the accuracy and stability of the pressure value measurement.

[0042] S40. Determine the pressure detection result of the cell preparation device according to the working pressure value.

[0043] Understandably, the pressure detection result is used to indicate whether there is an abnormality in the pressure values of each pipeline consumable when the cell preparation device is in the working state.

[0044] Optionally, in step S40, that is, determining the pressure detection result of the cell preparation device according to the working pressure value includes:

[0045] S401. Determine whether the working pressure value exceeds the preset pressure value range;

[0046] S402. If the working pressure value exceeds the preset pressure value range, confirm that the pressure detection result is abnormal working pressure, generate an abnormal prompt message, and control the cell preparation device to switch from the working state to the shutdown state.

[0047] Understandably, the preset pressure value range refers to the pre-set pressure value range. When the working pressure value does not exceed the preset pressure value range, it indicates that the pipeline consumable corresponding to this working pressure value is in a normal working pressure state. When the working pressure value exceeds the preset pressure value range, it indicates that the pipeline consumable corresponding to this working pressure value is in an abnormal working pressure state, and an abnormal prompt message is generated in a timely manner. Among them, the abnormal prompt message refers to the prompt message corresponding to this working pressure value, which is used to prompt the staff that the pipeline consumable corresponding to this working pressure value is in an abnormal working pressure state. For example, when the working pressure value exceeds the preset pressure value range, it indicates that the pipeline consumable is in an abnormal high working pressure state at this time, and the generated abnormal prompt message can be: There is a high pressure risk, suspected pipeline blockage, please pay attention to inspection. When the working pressure value is lower than the preset pressure value range, it indicates that the pipeline consumable is in an abnormal low working pressure state at this time, and the generated abnormal prompt message can be: There is a low pressure risk, suspected pipeline leakage, please pay attention to inspection. The shutdown state refers to the state where the cell preparation device is stopped from working. By measuring the working pressure value in real time, making judgments and feedback on the pressure conditions of the pipeline consumables in a timely manner, and controlling the cell preparation device to switch states, losses caused by abnormal working pressure of the pipeline consumables can be avoided.

[0048] In steps S10 - S40, when the pipeline consumables are not installed in the cell preparation device, the initial pressure value collected by the pressure acquisition device is obtained; when the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state, the empty tube pressure value in the pipeline consumables collected by the pressure acquisition device is obtained; after determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty tube pressure value, if the cell preparation device enters the working state, the working pressure value in the pipeline consumables is periodically collected by the pressure acquisition device; the pressure detection result of the cell preparation device is determined according to the working pressure value. In this embodiment, by using the initial pressure value and the empty tube pressure value to judge whether the airtightness of the pipeline consumables meets the airtightness requirements, the airtightness of the pipeline consumables can be accurately detected to ensure good airtightness of the pipeline consumables. Furthermore, based on the pipeline consumables with good airtightness, the working pressure value when the cell preparation device is in the working state is obtained. Through the dual pressure detection of the pipeline consumables, the double airtightness of the pipeline consumables is ensured, thus avoiding the waste of material and labor costs.

[0049] Optionally, before step S401, that is, before judging whether the working pressure value exceeds the preset pressure value range, it further includes:

[0050] S4011. Based on the initial pressure value and the empty tube pressure value, determine the lower limit value of the pressure of the preset pressure value range;

[0051] S4012. Based on the empty tube pressure value, determine the upper limit value of the pressure of the preset pressure value range.

[0052] It can be understood that the lower limit value of the pressure of the preset pressure value range is determined by the initial pressure value and the empty tube pressure value obtained by the pressure acquisition device. In this embodiment, since the initial pressure value obtained by the pressure acquisition device takes into account the error between the pressure value of the pressure acquisition device itself and the atmospheric pressure value, the determined lower limit value of the pressure is more accurate.

[0053] Optionally, the lower limit value of the pressure of the preset pressure value range is: P min = A(P1 - P2)+P2; or the lower limit value of the pressure of the preset pressure value range is: P min = -P0 + P2. Wherein: A is the pressure coefficient; P0 is the first pressure value greater than the preset pressure difference; P1 is the initial pressure value; P2 is the empty tube pressure value. The preset pressure difference is the pressure difference set in advance. For example, the preset pressure difference is 50 kPa and P0 is 80 kPa.

[0054] Optionally, the upper limit value of the pressure of the preset pressure value range is: P max= P2 + P3. Wherein, P3 is a second pressure value greater than P0. For example, P0 is 80 kPa and P3 is 120 kPa.

[0055] Optionally, after step S20, that is, after obtaining the empty tube pressure value in the pipeline consumable collected by the pressure acquisition device, the following steps are further included:

[0056] S201. Obtain the pressure difference between the empty tube pressure value and the initial pressure value;

[0057] S202. Determine whether the pressure difference is less than or equal to the preset pressure difference;

[0058] S203. If the pressure difference is less than or equal to the preset pressure difference, it is determined that the airtightness of the pipeline consumable meets the airtightness requirement.

[0059] It can be understood that the preset pressure difference refers to the pre-set pressure difference. For example, if the preset pressure difference is 50 kPa, when the pressure difference between the empty tube pressure value and the initial pressure value is less than or equal to 50 kPa, it is determined that the airtightness of the pipeline consumable meets the airtightness requirement. Otherwise, it is determined that the airtightness of the pipeline consumable does not meet the airtightness requirement. In this embodiment, by comparing the pressure difference between the empty tube pressure value and the initial pressure value with the preset pressure difference, it is judged whether the airtightness of the pipeline consumable meets the airtightness requirement to ensure good airtightness of the pipeline consumable after installation.

[0060] It should be understood that the magnitudes of the sequence numbers of the steps in the above embodiments do not mean the order of execution. The order of execution of each process should be determined by its function and internal logic, and should not constitute any limitation to the implementation process of the embodiments of the present invention.

[0061] In one embodiment, a pressure detection device is provided, which corresponds one-to-one with the pressure detection method in the above embodiment. As Figure 3 shown, the pressure detection device includes an initial pressure value module 10, an empty tube pressure value module 20, a working pressure value module 30, and a detection result module 40. The detailed description of each functional module is as follows:

[0062] The initial pressure value module 10 is used to obtain the initial pressure value collected by the pressure acquisition device when the pipeline consumable is not installed in the cell preparation device;

[0063] The empty tube pressure value module 20 is used to obtain the empty tube pressure value in the pipeline consumable collected by the pressure acquisition device when the pipeline consumable is installed in the cell preparation device and the cell preparation device is in an unstarted state;

[0064] The working pressure value module 30 is configured to, after determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty pipe pressure value, if the cell preparation device enters the working state, regularly collect the working pressure value in the pipeline consumables through the pressure acquisition device;

[0065] The detection result module 40 is configured to determine the pressure detection result of the cell preparation device according to the working pressure value.

[0066] Optionally, the detection result module 40 includes:

[0067] The first judgment unit is configured to judge whether the working pressure value exceeds the preset pressure value range;

[0068] The pressure abnormality unit is configured to, if the working pressure value exceeds the preset pressure value range, confirm that the pressure detection result is a working pressure abnormality, generate an abnormality prompt message, and control the cell preparation device to switch from the working state to the shutdown state.

[0069] Optionally, the pressure detection device further includes:

[0070] The pressure lower limit value unit is configured to determine the lower limit value of the preset pressure value range based on the initial pressure value and the empty pipe pressure value;

[0071] The pressure upper limit value unit is configured to determine the upper limit value of the preset pressure value range based on the empty pipe pressure value.

[0072] Optionally, the lower limit value of the preset pressure value range is: Pmin = A(P1 - P2) + P2; or the lower limit value of the preset pressure value range is: Pmin = -P0 + P2; where: A is the pressure coefficient; P0 is the first pressure value greater than the preset pressure difference; P1 is the initial pressure value; P2 is the empty pipe pressure value.

[0073] Optionally, the upper limit value of the preset pressure value range is: Pmax = P2 + P3; where P3 is the second pressure value greater than P0.

[0074] Optionally, in the pressure detection device, it further includes:

[0075] The pressure difference unit is configured to obtain the pressure difference between the empty pipe pressure value and the initial pressure value;

[0076] The second judgment unit is configured to judge whether the pressure difference is less than or equal to the preset pressure difference;

[0077] The airtightness determination unit is configured to, if the pressure difference is less than or equal to the preset pressure difference, determine that the airtightness of the pipeline consumables meets the airtightness requirements.

[0078] Optionally, the working pressure value module 30 includes:

[0079] An instantaneous pressure value unit for periodically collecting the instantaneous pressure value of the pipeline consumables through the pressure acquisition device;

[0080] A working pressure value unit for averaging all the collected instantaneous pressure values within a preset duration to obtain the average pressure value of the pipeline consumables within the preset duration, and recording the average pressure value as the working pressure value.

[0081] Optionally, the cell preparation device includes a centrifuge container with an air-permeable membrane; the pressure detection device includes a first pressure device arranged at the outlet end of the centrifuge container and a second pressure device arranged at the inlet end of the centrifuge container; the pipeline consumables include a first pipeline connecting the outlet end of the centrifuge container and clamped on the first pressure device, and a second pipeline connecting the inlet end of the centrifuge container and clamped on the second pressure device;

[0082] The empty pipe pressure value includes a first empty pipe pressure value of the first pipeline collected by the first pressure device and a second empty pipe pressure value of the second pipeline collected by the second pressure device;

[0083] The working pressure value includes a first working pressure value in the pipeline consumables collected by the first pressure device after the cell preparation device enters the working state and a second working pressure value in the pipeline consumables collected by the second pressure device after the cell preparation device enters the working state.

[0084] For the specific limitation of the pressure detection device, reference can be made to the limitation of the pressure detection method in the above text, which will not be elaborated here. Each module in the above pressure detection device can be implemented in whole or in part by software, hardware and their combination. The above modules can be embedded in the processor in the computer device in the form of hardware or be independent of it, or be stored in the memory in the computer device in the form of software, so that the processor can call and execute the operations corresponding to the above modules.

[0085] In one embodiment, a computer device is provided. The computer device can be a server, and its internal structure diagram can be as Figure 4As shown. The computer device includes a processor, a memory, a network interface, and a database connected by a system bus. Among them, the processor of the computer device is used to provide computing and control capabilities. The memory of the computer device includes a readable storage medium and an internal memory. The readable storage medium stores an operating system, computer-readable instructions, and a database. The internal memory provides an environment for the operation of the operating system and computer-readable instructions in the readable storage medium. The database of the computer device is used to store the data involved in the pressure detection method. The network interface of the computer device is used to communicate with an external terminal through a network connection. The computer-readable instructions, when executed by the processor, implement a pressure detection method. The readable storage medium provided in this embodiment includes a non-volatile readable storage medium and a volatile readable storage medium.

[0086] In one embodiment, a cell preparation device is provided. The cell preparation device includes a controller, a pressure detection device, tubing consumables, and a centrifuge container with an air-permeable membrane. Among them, the tubing consumables communicate with the centrifuge container; the tubing consumables are detachably clamped and installed on the pressure detection device; the controller is connected to the pressure detection device, and the controller is used to execute any one of the above pressure detection methods.

[0087] In one embodiment, one or more computer-readable storage media storing computer-readable instructions are provided. The readable storage media provided in this embodiment include non-volatile readable storage media and volatile readable storage media. Computer-readable instructions are stored on the readable storage media. When the computer-readable instructions are executed by one or more processors, the following steps are implemented:

[0088] When the tubing consumables are not installed in the cell preparation device, obtain the initial pressure value collected by the pressure acquisition device;

[0089] When the tubing consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state, obtain the empty tube pressure value in the tubing consumables collected by the pressure acquisition device;

[0090] After determining that the airtightness of the tubing consumables meets the airtightness requirements according to the initial pressure value and the empty tube pressure value, if the cell preparation device enters the working state, regularly collect the working pressure value in the tubing consumables through the pressure acquisition device;

[0091] Determine the pressure detection result of the cell preparation device according to the working pressure value.

[0092] Those of ordinary skill in the art can understand that all or part of the processes in the methods of the above embodiments can be completed by instructing relevant hardware through computer-readable instructions. The computer-readable instructions can be stored in a non-volatile readable storage medium or a volatile readable storage medium. When the computer-readable instructions are executed, they can include the processes of the embodiments of the above methods. Among them, any reference to a memory, storage, database, or other medium used in the various embodiments provided in this application can include non-volatile and / or volatile memories. Non-volatile memory can include read-only memory (ROM), programmable ROM (PROM), electrically programmable ROM (EPROM), electrically erasable programmable ROM (EEPROM), or flash memory. Volatile memory can include random access memory (RAM) or an external cache memory. By way of illustration and not limitation, RAM is available in various forms, such as static RAM (SRAM), dynamic RAM (DRAM), synchronous DRAM (SDRAM), double data rate SDRAM (DDR SDRAM), enhanced SDRAM (ESDRAM), synchronous link DRAM (SLDRAM), Rambus direct RAM (RDRAM), direct memory bus dynamic RAM (DRDRAM), and Rambus dynamic RAM (RDRAM), etc.

[0093] Those skilled in the art can clearly understand that for the convenience and brevity of description, only the above-mentioned division of each functional unit and module is used as an example. In actual applications, the above functions can be allocated to different functional units and modules according to needs, that is, the internal structure of the device can be divided into different functional units or modules to complete all or part of the functions described above.

[0094] The above embodiments are only used to illustrate the technical solutions of the present invention, rather than to limit them; although the present invention has been described in detail with reference to the foregoing embodiments, those of ordinary skill in the art should understand that they can still modify the technical solutions recorded in the foregoing embodiments, or perform equivalent replacements on some of the technical features; and these modifications or replacements do not make the essence of the corresponding technical solutions deviate from the spirit and scope of the technical solutions of the embodiments of the present invention, and should all be included in the protection scope of the present invention.

Claims

1. A pressure detection method, characterized in that, Including: When the pipeline consumables are not installed in the cell preparation device, obtaining the initial pressure value collected by the pressure acquisition device; When the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state, obtaining the empty pipe pressure value in the pipeline consumables collected by the pressure acquisition device; After determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the empty pipe pressure value, if the cell preparation device enters the working state, the working pressure value in the pipeline consumables is periodically collected by the pressure acquisition device; Determining the pressure detection result of the cell preparation device according to the working pressure value.

2. The pressure detection method according to claim 1, wherein The determining the pressure detection result of the cell preparation device according to the working pressure value includes: Judging whether the working pressure value exceeds a preset pressure value range; If the working pressure value exceeds the preset pressure value range, confirming that the pressure detection result is abnormal working pressure, generating an abnormal prompt message, and controlling the cell preparation device to switch from the working state to the shutdown state.

3. The pressure detection method according to claim 2, characterized in that Before judging whether the working pressure value exceeds the preset pressure value range, it further includes: Based on the initial pressure value and the empty pipe pressure value, determining the lower pressure limit value of the preset pressure value range; Based on the empty pipe pressure value, determining the upper pressure limit value of the preset pressure value range.

4. The pressure detection method according to claim 3, characterized in that, The lower limit value of the pressure within the preset pressure value range is: P min = A(P1 - P2)+P2; or The lower limit value of the pressure within the preset pressure value range is: P min = -P0 + P2; where: A is the pressure coefficient; P0 is the first pressure value greater than the preset pressure difference; P1 is the initial pressure value; P2 is the pressure value of the empty tube.

5. The pressure detection method according to claim 4, wherein The upper limit value of the pressure within the preset pressure value range is: P max = P2 + P3; Wherein, P3 is a second pressure value greater than P0.

6. The pressure detection method according to claim 4, wherein, After obtaining the empty pipe pressure value in the pipeline consumables collected by the pressure acquisition device, it further includes: Obtaining the pressure difference between the empty pipe pressure value and the initial pressure value; Judging whether the pressure difference is less than or equal to the preset pressure difference; If the pressure difference is less than or equal to the preset pressure difference, it is determined that the airtightness of the pipeline consumables meets the airtightness requirements.

7. The pressure detection method according to claim 1, wherein, The cell preparation device includes a centrifuge container with an air-permeable membrane; the pressure detection device includes a first pressure device arranged at the outlet end of the centrifuge container and a second pressure device arranged at the inlet end of the centrifuge container; the pipeline consumables include a first pipeline connecting the outlet end of the centrifuge container and clamped on the first pressure device, and a second pipeline connecting the inlet end of the centrifuge container and clamped on the second pressure device; The empty pipe pressure value includes a first empty pipe pressure value of the first pipeline collected by the first pressure device and a second empty pipe pressure value of the second pipeline collected by the second pressure device; The working pressure value includes a first working pressure value in the pipeline consumables collected by the first pressure device after the cell preparation device enters the working state and a second working pressure value in the pipeline consumables collected by the second pressure device after the cell preparation device enters the working state.

8. A pressure detection device, characterized in that, Including: An initial pressure value module, configured to obtain the initial pressure value collected by the pressure acquisition device when the pipeline consumables are not installed in the cell preparation device; An empty pipe pressure value module, configured to obtain the empty pipe pressure value in the pipeline consumables collected by the pressure acquisition device when the pipeline consumables are installed in the cell preparation device and the cell preparation device is in an unstarted state; A working pressure value module, configured to, after determining that the airtightness of the pipeline consumables meets the airtightness requirements according to the initial pressure value and the air pressure value in the empty tube, if the cell preparation device enters the working state, regularly collect the working pressure value in the pipeline consumables through the pressure acquisition device; A detection result module, configured to determine the pressure detection result of the cell preparation device according to the working pressure value.

9. A cell preparation device, characterized in that, It includes a controller, a pressure detection device, pipeline consumables, and a centrifuge container with an air-permeable membrane, and the pipeline consumables are connected to the centrifuge container; the pipeline consumables are detachably clamped and installed on the pressure detection device; the controller is connected to the pressure detection device, and the controller is configured to execute the pressure detection method according to any one of claims 1 to 7.

10. One or more readable storage media storing computer-readable instructions, characterized in that, When the computer-readable instructions are executed by one or more processors, the one or more processors are caused to execute the pressure detection method according to any one of claims 1 to 7.

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