Transdermal absorption composition and preparation method thereof

Abstract

The invention provides a transdermal absorption composition which is prepared from 60 to 100 parts of deionized water, 0.5 to 8 parts of a component A, 0.1 to 5 parts of a component B, 0.5 to 8 parts of 1, 3-propylene glycol, 0.02 to 0.5 part of p-hydroxyacetophenone, 0.1 to 1 part of xanthan gum, 0.01 to 0.2 part of EDTA (Ethylene Diamine Tetraacetic Acid) disodium, 0.001 to 0.5 part of a polygonum multiflorum extract, 0 to 0.8 part of essence, 0 to 3.2 parts of PEG-40 hydrogenated castor oil and 0 to 10 parts of ethanol, the component A is prepared from hydroxyethyl urea, water, acetyl triethyl citrate and propylene glycol; the component B is prepared from water, 1, 3-propylene glycol, a cacumen biotae extract, PEG-40 hydrogenated castor oil and EDTA (Ethylene Diamine Tetraacetic Acid) disodium; by integrating various components and cooperating with one another, the transdermal absorption rate of the product is improved, and the hair growing quality and efficiency of the product are remarkably improved.

Description

Technical Field

[0001] The present invention belongs to the technical field of preparation of absorption compositions, and particularly relates to a transdermal absorption composition and a preparation method thereof. Background Art

[0002] As a part of the body structure, hair has a direct protective effect on the scalp. External forces acting on the scalp can play a buffering role, reducing injuries and protecting the head. Due to the existence of hair, foreign objects cannot directly contact the scalp, avoiding contact with dust and bacteria. In traditional Chinese medicine, it is believed that hair is the surplus of blood, the kidney stores essence, and its luster is manifested in the hair. The growth of hair depends on the nourishment of essence and blood. Dense and shiny hair represents health and can give people a good image.

[0003] In reality, various hair diseases, such as hair loss, sparse hair, dandruff, etc., can cause adverse psychological effects such as inferiority and anxiety in people. In severe cases, it even affects social activities. Therefore, it is very important to pay attention to hair care in daily life.

[0004] Patent CN118845976A provides a traditional Chinese medicine hair growth liquid with the functions of preventing hair loss and promoting hair growth. The extraction liquid is obtained by repeatedly decocting traditional Chinese medicine additives, and the extraction liquid is concentrated. The obtained concentrated liquid is then mixed with the remaining raw materials, and the hair growth liquid is obtained after filtration; the hair growth liquid provided by the present invention is rich in natural plant essences and traditional Chinese medicine plant components, deeply nourishes the hair, promotes the metabolism of the hair scalp cutin membrane, improves the hair growth environment, strengthens the absorption of root nutrition, consolidates the growth of hair roots, and reduces the occurrence of hair loss and hair breakage; the preparation process flow of the hair growth liquid is simple, easy to operate, has low production costs, and high production efficiency.

[0005] There are a variety of existing hair growth hair conditioners and hair care liquids on the market, with different effects. For example, there are those for removing dandruff, preventing hair from becoming dry, and for nutritional care, etc. However, some products have certain side effects on hair and skin, which are not conducive to people's physical health, and the transdermal penetration effect is not good, affecting the care effect. Summary of the Invention

[0006] The purpose of the present invention is to provide a transdermal absorption composition and a preparation method thereof. By integrating multiple components and cooperating with each other synergistically, the transdermal absorption effect of the product is improved, and the quality and efficiency of hair growth of the product are significantly improved.

[0007] To achieve the above purpose, the present invention provides the following technical solutions: A transdermal absorption composition, comprising 60 - 100 parts of deionized water, 0.5 - 8 parts of component A, 0.1 - 5 parts of component B, 0.5 - 8 parts of 1,3 - propanediol, 0.02 - 0.5 parts of p - hydroxyacetophenone, 0.1 - 1 part of xanthan gum, 0.01 - 0.2 parts of disodium EDTA, 0.001 - 0.5 parts of Polygonum multiflorum Thunb. extract, 0 - 0.8 parts of essence, 0 - 3.2 parts of PEG - 40 hydrogenated castor oil, and 0 - 10 parts of ethanol. Component A consists of hydroxyethyl urea, water, triethyl acetyl citrate, and propylene glycol; component B consists of water, 1,3 - propanediol, Platycladus orientalis (L.) Franco extract, PEG - 40 hydrogenated castor oil, and disodium EDTA.

[0008] Furthermore, the mass ratio of hydroxyethyl urea, water, triethyl acetyl citrate, and propylene glycol in component A is 3 - 5:35 - 45:5 - 10:15 - 25; the mass ratio of water, 1,3 - propanediol, Platycladus orientalis (L.) Franco extract, PEG - 40 hydrogenated castor oil, and disodium EDTA in component B is 40 - 50:5 - 10:4 - 8 parts:10 - 20:5 - 8.

[0009] Furthermore, it further comprises 0.1 - 5 parts of component C and 0.1 - 5 parts of component D; component C consists of water, Chrysanthemum indicum L. extract, Lonicera japonica Thunb. extract, Rheum palmatum L. root extract, Matricaria recutita L. extract, Sophora flavescens Aiton root extract, phenoxyethanol, and ethylhexylglycerin; component D consists of glycerol, water, 1,2 - pentanediol, Salvia miltiorrhiza Bunge root extract, Eugenia caryophyllata Thunb. bud extract, Angelica sinensis (Oliv.) Diels root extract, Glycyrrhiza glabra L. root extract, Centella asiatica (L.) Urban extract, disodium EDTA, and xanthan gum.

[0010] Furthermore, the mass ratio of water, Chrysanthemum indicum L. extract, Lonicera japonica Thunb. extract, Rheum palmatum L. root extract, Matricaria recutita L. extract, Sophora flavescens Aiton root extract, phenoxyethanol, and ethylhexylglycerin in component C is 40 - 50:3 - 6:2 - 5:4 - 7:2 - 5:1 - 3:10 - 20:5 - 10; the mass ratio of glycerol, water, 1,2 - pentanediol, Salvia miltiorrhiza Bunge root extract, Eugenia caryophyllata Thunb. bud extract, Angelica sinensis (Oliv.) Diels root extract, Glycyrrhiza glabra L. root extract, Centella asiatica (L.) Urban extract, disodium EDTA, and xanthan gum in component D is 10 - 20:50 - 70:5 - 10:1 - 3:2 - 4:1 - 3:2 - 4:3 - 5:3 - 6:5 - 10.

[0011] Furthermore, it further comprises 0.1 - 0.5 parts of component E and 0.01 - 5 parts of component F; component E consists of 1,3 - propanediol, 1,2 - hexanediol, and octanoyl hydroxamic acid; component F consists of water, glycerol, trehalose, Dendrobium nobile Lindl. stem extract, Aloe barbadensis Miller leaf extract, Sophora flavescens Aiton root extract, 1,2 - pentanediol, 1,2 - hexanediol, Lycium barbarum L. fruit extract, and Echinacea purpurea (L.) Moench extract.

[0012] Furthermore, the mass ratio of 1,3-propanediol, 1,2-hexanediol and octanoyl hydroxamic acid in the E component is 10-20:15-20:5-10; the mass ratio of water, glycerol, trehalose, Dendrobium nobile stem extract, Aloe barbadensis leaf extract, Sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, Lycium barbarum fruit extract, and Echinacea purpurea extract in the F component is 50-60:8-10:5-10:1-3:2-4:1-3:5-10:3-5:1-3:2-4.

[0013] Furthermore, it also includes 0.01-5 parts of G component and 0.01-5 parts of H component; the G component is composed of water, butanediol, Angelica sinensis root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Glycyrrhiza glabra root extract and xanthan gum; the H component is composed of hydrolyzed ginsenosides and butanediol.

[0014] Furthermore, the mass ratio of water, butanediol, Angelica sinensis root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Glycyrrhiza glabra root extract and xanthan gum in the G component is 30-50:5-10:1-3:2-5:1-3:1-4:2-4:5-10; the mass ratio of hydrolyzed ginsenosides and butanediol in the H component is 5-10:10-20.

[0015] Furthermore, it also includes 0.01-2 parts of I component, 0.001-1 part of J component and 0.01-2 parts of K component; the I component is composed of bisabolol and Zingiber officinale root extract; the J component is composed of water, 1,3-propanediol and Crocus sativus flower extract; the K component is composed of Smilax glabra extract, Phragmites communis extract, citric acid and sodium citrate.

[0016] Furthermore, the mass ratio of bisabolol and Zingiber officinale root extract in the I component is 5-10:1-3; the mass ratio of water, 1,3-propanediol and Crocus sativus flower extract in the J component is 50-60:5-10:1-3; the mass ratio of Smilax glabra extract, Phragmites communis extract, citric acid and sodium citrate in the K component is 5-10:4-8:10-20:7-10.

[0017] Furthermore, each component is configured and mixed according to the ratio, and ultrasonic treatment is carried out at a temperature of 40-60°C and 600-700W for 1-2h to obtain the transdermal absorption composition.

[0018] Compared with the prior art, the advantages and beneficial effects of the present invention are: The present invention adds components such as polygonum multiflorum extract, platycladus orientalis leaf extract, hydrogenated castor oil, chamomilla recutita extract, lonicera japonica flower extract, rheum palmatum root extract, chamomilla recutita extract, sophora flavescens root extract, phenoxyethanol and ethylhexylglycerin, salvia miltiorrhiza root extract, syzygium aromaticum bud extract, angelica sinensis root extract, glycyrrhiza glabra root extract, centella asiatica extract, disodium edta and xanthan gum. By utilizing the synergistic effect of various extracts and components, the composition has moderate lipophilicity and hydrophilicity, can dissolve in skin lipids and disperse in the water phase, and at the same time, by temporarily changing the structure of the stratum corneum, its permeability is increased; enabling the overall components to be better absorbed through the skin and promoting transdermal nourishment and protection. Detailed implementation mode

[0019] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative efforts belong to the protection scope of the present invention.

[0020] Example 1 This example provides a preparation method of a transdermal absorption composition, including the following steps: S1: Each component is prepared according to the ratio respectively. Hydroxyethyl urea, water, triethyl acetylcitrate and propylene glycol are stirred and mixed evenly according to a mass ratio of 3:35:5:15 to obtain component A; Water, 1,3-propanediol, platycladus orientalis leaf extract, PEG-40 hydrogenated castor oil and disodium edta are stirred and mixed evenly according to a mass ratio of 40:5:4:10:5 to obtain component B; Water, chamomilla recutita extract, lonicera japonica flower extract, rheum palmatum root extract, chamomilla recutita extract, sophora flavescens root extract, phenoxyethanol and ethylhexylglycerin are mixed evenly according to a mass ratio of 40:3:2:4:2:1:10:5 to obtain component C; Glycerol, water, 1,2-pentanediol, salvia miltiorrhiza root extract, syzygium aromaticum bud extract, angelica sinensis root extract, glycyrrhiza glabra root extract, centella asiatica extract, disodium edta and xanthan gum are mixed evenly according to a weight ratio of 20:70:10:3:4:3:4:5:6:10 to obtain component D; 1,3-propanediol, 1,2-hexanediol and octanoyl hydroxamic acid are stirred evenly according to a mass ratio of 20:20:10 to obtain component E; Mix water, glycerol, trehalose, Dendrobium nobile Lindl. stem extract, Aloe barbadensis Miller leaf extract, Sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, Lycium barbarum fruit extract, and Echinacea purpurea extract evenly according to the mass ratio of 50:8:5:1:2:1:5:3:1:2 to obtain component F; Mix water, butanediol, Angelica sinensis root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Glycyrrhiza glabra root extract, and xanthan gum evenly according to the mass ratio of 30:5:1:2:1:1:2:5 to obtain component G; Mix hydrolyzed ginsenosides and butanediol evenly according to the mass ratio of 5:10 to obtain component H; Mix bisabolol and Zingiber officinale root extract evenly according to the mass ratio of 5:1 to obtain component I; mix water, 1,3-propanediol, and Crocus sativus flower extract evenly according to the mass ratio of 50:5:1 to obtain component J; mix Polyporus umbellatus extract, Phragmites communis extract, citric acid, and sodium citrate evenly according to the mass ratio of 5:4:10:7 to obtain component K; S2: Add 60 g of deionized water, 0.5 g of component A, 0.1 g of component B, 0.1 g of component C, 0.1 g of component D, 0.1 g of component E, 0.01 g of component F, 0.01 g of component G, 0.01 g of component H, 0.01 g of component I, 0.001 g of component J, 0.01 g of component K, 0.5 g of 1,3-propanediol, 0.02 g of p-hydroxyacetophenone, 0.1 g of xanthan gum, 0.01 g of disodium EDTA, and 0.001 g of Polygonum multiflorum Thunb. extract into a reaction kettle, and treat at a temperature of 40°C at a rate of 600 r / min for 2 h to obtain the transdermal absorption composition.

[0021] Example 2 This example provides a preparation method of a transdermal absorption composition, including the following steps: S1: Prepare each component according to the ratio respectively. Mix hydroxyethyl urea, water, triethyl acetyl citrate, and propylene glycol evenly according to the mass ratio of 5:45:10:25 to obtain component A; Mix water, 1,3-propanediol, Platycladus orientalis leaf extract, PEG-40 hydrogenated castor oil, and disodium EDTA evenly according to the mass ratio of 50:10:8:20:8 to obtain component B; Mix water, Chrysanthemum indicum extract, Lonicera japonica flower extract, Rheum palmatum root extract, Matricaria recutita extract, Sophora flavescens root extract, phenoxyethanol, and ethylhexylglycerin evenly according to the mass ratio of 50:6:5:7:5:3:20:10 to obtain component C; Mix glycerol, water, 1,2-pentanediol, Salvia miltiorrhiza root extract, clove bud extract, Angelica sinensis root extract, Glycyrrhiza glabra root extract, Centella asiatica extract, disodium EDTA, and xanthan gum evenly according to the weight ratio of 20:70:10:3:4:3:4:5:6:10 to obtain Component D; Stir 1,3-propanediol, 1,2-hexanediol, and octanoyl hydroxamic acid evenly according to the mass ratio of 20:20:10 to obtain Component E; Stir water, glycerol, trehalose, Dendrobium nobile stem extract, Aloe barbadensis leaf extract, Sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, Lycium barbarum fruit extract, and Echinacea purpurea extract evenly according to the mass ratio of 60:10:10:3:4:3:10:5:3:4 to obtain Component F; Stir water, butanediol, Angelica sinensis root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Glycyrrhiza glabra root extract, and xanthan gum evenly according to the mass ratio of 50:10:3:5:3:4:4:10 to obtain Component G; Stir hydrolyzed ginsenosides and butanediol evenly according to the mass ratio of 10:20 to obtain Component H; Stir bisabolol and ginger root extract evenly according to the mass ratio of 10:3 to obtain Component I; stir water, 1,3-propanediol, and saffron flower extract evenly according to the mass ratio of 60:10:3 to obtain Component J; stir Poria cocos extract, Phragmites communis extract, citric acid, and sodium citrate evenly according to the mass ratio of 10:8:20:10 to obtain Component K; S2: Take 100 g of deionized water, 8 g of Component A, 5 g of Component B, 5 g of Component C, 5 g of Component D, 0.5 g of Component E, 5 g of Component F, 5 g of Component G, 5 g of Component H, 2 g of Component I, 1 g of Component J, 2 g of Component K, 8 g of 1,3-propanediol, 0.5 g of p-hydroxyacetophenone, 1 g of xanthan gum, 0.2 g of disodium EDTA, 0.5 g of Polygonum multiflorum extract, 0.8 g of essence, 3.2 g of PEG-40 hydrogenated castor oil, and 10 g of ethanol and add them to a reaction kettle. Treat at a temperature of 60 °C at a rate of 800 r / min for 4 h to obtain the transdermal absorption composition.

[0022] Example 3 This example provides a preparation method of a transdermal absorption composition, including the following steps: S1: Prepare each component according to the ratio respectively. Stir and mix hydroxyethyl urea, water, triethyl acetyl citrate, and propylene glycol evenly according to the mass ratio of 4:40:7:22 to obtain Component A; Stir and mix water, 1,3-propanediol, Platycladus orientalis leaf extract, PEG-40 hydrogenated castor oil, and disodium EDTA evenly according to the mass ratio of 45:7:6:15:6 to obtain Component B; Mix water, wild chrysanthemum extract, honeysuckle flower extract, rhubarb root extract, chamomile extract, sophora flavescens root extract, phenoxyethanol and ethylhexylglycerin evenly according to the mass ratio of 45:5:3:6:3:2:15:8 to obtain Component C; Mix glycerin, water, 1,2-pentanediol, salvia root extract, clove bud extract, angelica root extract, licorice root extract, centella asiatica extract, disodium EDTA and xanthan gum evenly according to the weight ratio of 15:65:7:2:3:2:3:4:5:7 to obtain Component D; Stir 1,3-propanediol, 1,2-hexanediol and octanoyl hydroxamic acid evenly according to the mass ratio of 15:17:8 to obtain Component E; Mix water, glycerin, trehalose, dendrobium officinale stem extract, aloe barbadensis leaf extract, sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, wolfberry fruit extract and echinacea purpurea extract evenly according to the mass ratio of 55:9:7:2:3:2:7:4:2:3 to obtain Component F; Mix water, butanediol, angelica root extract, notoginseng root extract, astragalus membranaceus root extract, ligustrum lucidum fruit extract, licorice root extract and xanthan gum evenly according to the mass ratio of 40:7:2:4:2:3:3:8 to obtain Component G; Stir hydrolyzed ginsenosides and butanediol evenly according to the mass ratio of 7:16 to obtain Component H; Stir bisabolol and ginger root extract evenly according to the mass ratio of 8:2 to obtain Component I; Stir water, 1,3-propanediol and saffron flower extract evenly according to the mass ratio of 55:8:2 to obtain Component J; Stir polyporus umbellatus extract, phragmites australis extract, citric acid and sodium citrate evenly according to the mass ratio of 8:6:15:8 to obtain Component K; S2: Take 80 g of deionized water, 5.5 g of Component A, 3 g of Component B, 3.5 g of Component C, 2.5 g of Component D, 0.3 g of Component E, 3 g of Component F, 2.5 g of Component G, 3.5 g of Component H, 1 g of Component I, 0.2 g of Component J, 1.5 g of Component K, 4.5 g of 1,3-propanediol, 0.3 g of p-hydroxyacetophenone, 0.5 g of xanthan gum, 0.15 g of disodium EDTA, 0.3 g of polygonum multiflorum extract, 0.4 g of essence, 2.3 g of PEG-40 hydrogenated castor oil and 7 g of ethanol and add them to a reaction kettle, and process them at a temperature of 55°C at a rate of 750 r / min for 3.5 h to obtain the transdermal absorption composition.

[0023] Comparative Example 1 Purchase a commercially available hair conditioner.

[0024] Performance test: Refer to the standard of "Test method for in vitro skin absorption of chemicals" GB / T 27818-2011. In this test, piglet skin was selected as the test model, and the piglet skin-Franz cell diffusion cell system was selected as the test system. The transdermal differences of the transdermal absorption compositions prepared in each example and comparative example were tested, and the test results are shown in the table.

[0025]

[0026] From the above performance test results, it can be seen that the transdermal absorption compositions prepared in Examples 1-3 have excellent performance; especially Example 3. The commercially available comparative example is significantly worse than the examples in the corresponding performance tests because it does not adopt the necessary technical solutions. The above experimental results further prove the importance of the technical solutions defined in the present invention for its technical effects.

[0027] The above is the preferred embodiment of the present invention. It should be noted that for those of ordinary skill in the art, without departing from the principle of the present invention, several improvements and refinements can be made, and these improvements and refinements should also be regarded as the protection scope of the present invention.

Claims

1. A transdermal absorption composition, characterized in that: The invention comprises 60-100 parts of deionized water, 0.5-8 parts of component A, 0.1-5 parts of component B, 0.5-8 parts of 1,3-propylene glycol, 0.02-0.5 parts of p-hydroxyacetophenone, 0.1-1 parts of xanthan gum, 0.01-0.2 parts of disodium EDTA, 0.001-0.5 parts of Polygonum multiflorum extract, 0-0.8 parts of essence, 0-3.2 parts of PEG-40 hydrogenated castor oil and 0-10 parts of ethanol, wherein the component A consists of hydroxyethyl urea, water, acetyl triethyl citrate and propylene glycol; and the component B consists of water, 1,3-propylene glycol, Platycladus orientalis leaf extract, PEG-40 hydrogenated castor oil and disodium EDTA.

2. A transdermal absorption composition according to claim 1, characterized in that: The mass ratio of hydroxyethyl urea, water, triethyl acetyl citrate and propylene glycol in component A is 3-5:35-45:5-10:15-25; the mass ratio of water, 1,3-propylene glycol, Platycladus orientalis leaf extract, PEG-40 hydrogenated castor oil and disodium EDTA in component B is 40-50:5-10:4-8:10-20:5-8.

3. A transdermal absorption composition according to claim 1, characterized in that: It also includes 0.1-5 parts of component C and 0.1-5 parts of component D; the component C is composed of water, wild chrysanthemum extract, honeysuckle extract, palm leaf rhubarb root extract, golden chamomile extract, sophora flavescens root extract, phenoxyethanol and ethylhexylglycerin; the component D is composed of glycerin, water, 1,2-pentanediol, salvia miltiorrhiza root extract, clove bud extract, angelica root extract, licorice root extract, Centella asiatica extract, disodium EDTA and xanthan gum.

4. A transdermal absorption composition according to claim 3, characterized in that: The mass ratio of water, wild chrysanthemum extract, honeysuckle extract, rheum palmatum root extract, golden chamomile extract, sophora flavescens root extract, phenoxyethanol and ethylhexylglycerin in the C component is 40-50: 3-6: 2-5: 4-7: 2-5: 1-3: 10-20: 5-10; the mass ratio of glycerin, water, 1,2-pentanediol, salvia miltiorrhiza root extract, clove bud extract, angelica root extract, licorice root extract, Centella asiatica extract, disodium EDTA and xanthan gum is 10-20: 50-70: 5-10: 1-3: 2-4: 1-3: 2-4: 3-5: 3-6: 5-10.

5. A transdermal absorption composition according to claim 1, characterized in that: It also includes 0.1-0.5 parts of component E and 0.01-5 parts of component F; the component E is composed of 1,3-propylene glycol, 1,2-hexanediol and caprylhydroxamic acid; the component F is composed of water, glycerin, trehalose, Dendrobium nobile stem extract, Aloe vera leaf extract, Sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, Lycium barbarum fruit extract, and Echinacea purpurea extract.

6. A transdermal absorption composition according to claim 1, characterized in that: The mass ratio of 1,3-propylene glycol, 1,2-hexanediol and caprylhydroxamic acid in the E component is 10-20:15-20:5-10; the mass ratio of water, glycerin, trehalose, Dendrobium nobile stem extract, Aloe vera leaf extract, Sophora flavescens root extract, 1,2-pentanediol, 1,2-hexanediol, Lycium barbarum fruit extract and Echinacea purpurea extract in the F component is 50-60:8-10:5-10:1-3:2-4:1-3:5-10:3-5:1-3:2-4.

7. A transdermal absorption composition according to claim 1, characterized in that: It also includes 0.01-5 parts of component G and 0.01-5 parts of component H; the component G is composed of water, butylene glycol, angelica root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Licorice root extract and xanthan gum; the component H is composed of hydrolyzed ginsenosides and butylene glycol.

8. A transdermal absorption composition according to claim 1, characterized in that: The mass ratio of water, butylene glycol, angelica root extract, Panax notoginseng root extract, Astragalus membranaceus root extract, Ligustrum lucidum fruit extract, Licorice root extract and xanthan gum in the G component is 30-50: 5-10: 1-3: 2-5: 1-3: 1-4: 2-4: 5-10; the mass ratio of hydrolyzed ginsenosides and butylene glycol in the H component is 5-10: 10-20.

9. A transdermal absorption composition according to claim 1, characterized in that: It also includes 0.01-2 parts of component I, 0.001-1 parts of component J and 0.01-2 parts of component K; the component I consists of bisabolol and ginger root extract; the component J consists of water, 1,3-propylene glycol and saffron flower extract; the component K consists of water tuckahoe extract, reed extract, citric acid and sodium citrate.

10. A transdermal absorption composition according to claim 1, characterized in that: The mass ratio of bisabolol to ginger root extract in component I is 5-10:1-3; the mass ratio of water, 1,3-propylene glycol and saffron flower extract in component J is 50-60:5-10:1-3; the mass ratio of water Poria cocos extract, reed extract, citric acid and sodium citrate in component K is 5-10:4-8:10-20:7-10.

11. A method for preparing a transdermal absorption composition, characterized in that: The components are prepared according to the ratio and then mixed, and ultrasonically treated at a temperature of 40-60° C. and 600-700W for 1-2 hours to obtain the transdermal absorption composition.

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