Efficient moisturizing lotion composition and preparation method thereof

Abstract

The invention relates to the field of cosmetics, in particular to an efficient moisturizing lotion composition and a preparation method thereof. The invention discloses a high-efficiency moisturizing lotion composition. The lotion composition comprises the following raw material components: a phase A, a phase B, a phase C, a phase D and a phase E, the moisturizing agent forms a'moisture absorption-water locking-film forming 'three-stage moisturizing system through glycerol, cross-linked sodium hyaluronate and hydroxyethyl urea, and the moisturizing time efficiency is remarkably prolonged. And a multi-vitamin emulsion system of the thickening agent and 16 / 18 alcohol realizes high stability under low viscosity and promotes rapid absorption. The shea butter and the vitamin E cooperate to supplement lipid, resist oxidation and enhance the skin barrier function. Through molecular design, system innovation and process optimization, technical breakthrough is realized in the aspects of moisturizing aging, absorption speed, stability, skin repair and the like, and an innovative solution is provided for developing a new generation of functional skin care products.

Description

Technical Field

[0001] This application relates to the field of cosmetics, and particularly to a highly efficient moisturizing body lotion composition and a preparation method thereof. Background Art

[0002] A body lotion, which is a type of emulsion, can deeply moisturize dry skin and replenish the moisture lost by the skin every day. The body lotion can quickly penetrate and deeply moisturize the skin, making it regain softness, smoothness, and full luster.

[0003] In daily life, as a basic skin care product, body lotions are widely used. However, most of the existing body lotions contain a large number of chemical additives, synthetic fragrances, etc. The relatively complex ingredients are not conducive to continuous skin care, and can only keep the skin surface moist for a short time during use. Most traditional body lotions rely on a single or a small amount of moisturizing ingredients, such as glycerin or hyaluronic acid, while ignoring the importance of the synergistic effect of multiple ingredients, resulting in limited moisturizing effects.

[0004] With the increasing demand of consumers for skin care, developing a new generation of body lotions with long-lasting moisturization, easy absorption, mildness and no irritation, and the ability to enhance the skin barrier function has become a key point that the industry urgently needs to break through. Summary of the Invention

[0005] Aiming at the deficiencies of the current technology, this application provides a highly efficient moisturizing body lotion composition and a preparation method thereof. The highly efficient moisturizing body lotion composition of this application is mild and non-irritating, highly stable, has excellent moisturizing effects, and is quickly absorbed.

[0006] In the first aspect, this application provides a highly efficient moisturizing body lotion composition, adopting the following technical solution: A highly effective moisturizing body lotion composition, wherein the raw material components of the body lotion composition include phase A, phase B, phase C, phase D and phase E; the phase A, by weight, includes the following raw materials: 72-75 parts of deionized water, 0.04-0.06 parts of EDTA-2Na, 0.09-0.11 parts of allantoin, 2.0-2.3 parts of a moisturizer, and 0.25-0.35 parts of a thickener; the phase B, by weight, includes the following raw materials: 1.4-1.6 parts of 16 / 18 alcohol, 9-11 parts of 26# white oil, 2.8-3.2 parts of ethylhexyl isononanoate, and 0.45-0. .55 parts, shea butter 0.9-1.1 parts, complex surfactant 1.2-1.4 parts, stearic acid 0.9-1.1 parts, glyceryl stearate 0.7-0.9 parts, skin conditioner 0.45-0.55 parts; the C phase, calculated by mass, includes the following raw materials: acrylic acid (ester) / ammonium methacrylate copolymer 0.45-0.55 parts; the D phase, calculated by mass, includes the following raw materials: pH adjuster 0.08-0.12 parts; the E phase, calculated by mass, includes the following raw materials: preservative 0.5-0.6 parts, flavor 0.45-0.55 parts.

[0007] By adopting the above technical scheme, deionized water is used as the base solvent, which accounts for the main body of the formula, dissolves water-soluble ingredients, and adjusts the fluidity of the system. EDTA-2Na is used as a chelating agent to bind metal ions, prevent oxidation and microbial contamination, and prolong product stability. Allantoin promotes moisture retention in the stratum corneum and has both anti-inflammatory and soothing effects. 16 / 18 alcohol is used as an emulsifier and emollient to promote emulsification of the oil-water phase and provide a smooth skin feel. 26# white oil is used as an occlusive emollient to form a protective film, reduce water evaporation, and enhance moisturizing durability. Ethylhexyl isononanoate improves spreadability, reduces greasy feeling, and promotes the penetration of active ingredients. Vitamin E is used as an antioxidant to neutralize free radicals, prevent oil oxidation, and assist in moisturizing the skin. Shea butter is a natural lipid source rich in fatty acids, strengthens the skin barrier, and repairs dry and damaged skin. Acrylic acid (ester) / ammonium methacrylate copolymer is used as a film former and thickener to form a breathable moisturizing film to improve skin feel and durability. The moisturizer forms a three-level moisturizing system of "moisture absorption-water lock-film formation", which significantly prolongs the moisturizing time. The thickener and 16 / 18 alcohol form a multi-dimensional emulsification system, which achieves high stability under low viscosity and promotes rapid absorption. Shea butter and vitamin E work together to supplement lipids and resist oxidation, and enhance the skin barrier function. Through the synergistic effect of the above components, the prepared high-efficiency moisturizing lotion composition has mildness, no irritation, high stability, excellent moisturizing effect and rapid absorption.

[0008] Preferably, the moisturizing agent consists of glycerin, cross-linked sodium hyaluronate and hydroxyethyl urea in a mass ratio of 20:1:1.

[0009] By adopting the above technical solution, glycerol is a polyol with good hygroscopicity, capable of absorbing moisture from the environment and locking in the moisture on the skin surface to prevent water evaporation. Cross-linked sodium hyaluronate is a cross-linked derivative of hyaluronic acid, with stronger moisturizing ability and biocompatibility, capable of forming a protective film on the skin surface to lock in moisture and improve the elasticity and luster of the skin. Hydroxyethyl urea is a urea derivative with good moisturizing property and permeability, capable of helping the skin retain moisture and promoting the absorption of other active ingredients. The synergistic effect among these three ingredients is mainly reflected in the following aspects: 1. Moisture absorption - water locking - film forming: Glycerol, as a moisture absorbent, can absorb moisture from the environment; cross-linked sodium hyaluronate, as a water locking agent, can form a protective film on the skin surface to prevent water loss; hydroxyethyl urea, as a film forming agent, helps the skin retain moisture and promotes the absorption of other active ingredients. 2. Enhancing the moisturizing effect: The combined use of these three ingredients can significantly extend the moisturizing time limit and improve the moisturizing effect of the skin. 3. Promoting skin health: The combined use of these three ingredients can help the skin retain moisture, prevent dryness and dehydration, thus promoting skin health. 4. Improving the stability of the product: The combined use of these three ingredients can improve the stability of the product and extend the shelf life of the product. Generally speaking, the synergistic effect of glycerol, cross-linked sodium hyaluronate and hydroxyethyl urea in the moisturizer is mainly reflected in aspects such as moisture absorption - water locking - film forming, enhancing the moisturizing effect, promoting skin health and improving the stability of the product.

[0010] Preferably, the cross-linked sodium hyaluronate is sodium hyaluronate with a molecular weight of 50,000 - 100,000 Daltons, which is obtained by cross-linking with a cross-linking agent polyglycerol polyglycidyl ether.

[0011] Preferably, the preparation method of the cross-linked sodium hyaluronate includes the following steps: S41: According to the mass parts: Add 15 parts of sodium hyaluronate with a molecular weight of 50,000 - 100,000 Daltons and 5 parts of NaCl into 500 parts of a NaOH solution with a mass concentration of 0.04%, and stir at room temperature until completely dissolved to obtain a mixed solution A; S42: According to the mass parts: Take 3 parts of polyglycerol polyglycidyl ether, dilute and stir evenly with 300 parts of distilled water to obtain a polyglycerol polyglycidyl ether solution; S43: Heat the mixed solution A to 43°C, keep it at a constant temperature, and drop the polyglycerol polyglycidyl ether solution into the mixed solution A, finish dropping within 80 minutes, and continue the constant temperature reaction for 9 - 10 hours after dropping; S44: According to the mass parts: Add a 0.02 mol / L citric acid solution to adjust the pH to 7.2 - 7.4, stir for 3 - 4 hours, then add 1200 parts of absolute ethanol, precipitate for 6 - 7 hours to obtain a block solid; S45. After freezing the bulk solid at -70°C under a vacuum pressure of 80 Pa for 24 hours, dialysis is carried out for 24 hours according to the dosage of 1 g of bulk solid: 300 mL of normal saline, and the dialyzed gel is freeze-dried again to obtain cross-linked sodium hyaluronate.

[0012] By adopting the above technical solution, alkali-soluble cross-linking: Sodium hyaluronate and NaCl are dissolved in a 0.04% NaOH solution, and a polyglycerol polyglycidyl ether cross-linking agent is added, and the reaction is carried out at a constant temperature of 43°C for 9 - 10 hours to form a three-dimensional network structure. The reaction is terminated by adjusting to neutral with citric acid, and impurities are removed by freeze-drying at -70°C and dialysis with normal saline after ethanol precipitation, and finally a high-purity cross-linked product is obtained. By controlling the dosage of the cross-linking agent and the reaction time, a low cross-linking degree is achieved, and the balance between moisture retention and biocompatibility is realized. Long-lasting water locking: After cross-linking, the molecular weight increases (50,000 - 100,000 → more than 500,000), forming a breathable water-retaining film, and the water-locking ability is significantly improved compared with ordinary HA. Together with glycerol (moisture absorption) and hydroxyethyl urea (film-forming), a three-level moisture retention system is formed, and the moisture retention time is extended to 12 hours. The film-forming property is enhanced by an acrylic copolymer, and the evaporation of water is reduced synergistically with 26# white oil. The anti-enzymatic hydrolysis ability of the cross-linked structure is enhanced, and the viscosity retention rate is >90% within the pH range of 6 - 7, ensuring the storage stability of the formulation. This preparation method makes the product have both high moisture retention and low irritation by precisely controlling the cross-linking degree (reaction time in step S43) and the purification process (dialysis in S45), and forms a functional complement with shea butter (repairing the barrier) and vitamin E (antioxidation) in the formulation, realizing the triple synergy of "moisture retention - repair - protection".

[0013] Preferably, the thickener is composed of xanthan gum and carbomer U20 in a mass ratio of 1:2.

[0014] Preferably, the composite surfactant is composed of sodium lauroyl lactylate and polysorbate - 60 in a mass ratio of 5:8.

[0015] By adopting the above technical solution, the composite surfactant consists of sodium lauroyl lactylate and polysorbate-60. These two components are combined in a specific ratio, which can enhance the emulsifying effect of the product, improve the stability and skin feel of the lotion. Sodium lauroyl lactylate: As an anionic surfactant, it has excellent emulsifying ability and penetration-promoting effect. The long-chain alkyl group in its molecular structure can insert into the oil phase, while the lactate group is anchored in the water phase, forming a stable micelle structure, reducing the oil-water interfacial tension. And polysorbate-60: The nonionic surfactant forms a hydrated layer through the polyoxyethylene chain, enhancing the low-temperature stability of the system. Its branched-chain structure can effectively reduce the solid / liquid interfacial tension and improve the wettability. Emulsification dimension complementarity: The combination of anionic and nonionic surfactants broadens the applicable range of the HLB value, achieving high-stability emulsification at low viscosity and supporting the design goal of the "multi-dimensional emulsification system". Penetration synergy: Sodium lauroyl lactylate promotes penetration by changing the lipid arrangement in the stratum corneum, while polysorbate-60 carries active ingredients (such as vitamin E and shea butter) into the skin through solubilization, forming a delivery channel. Skin feel balance: Sodium lauroyl lactylate provides a delicate and smooth feeling, while polysorbate-60 reduces the residual sticky feeling, synergistically achieving the "quick absorption" characteristic. It forms a composite emulsification network with 16 / 18 alcohols, stearic acid, etc. in the formula, and cooperates with the film-forming effect of the acrylic copolymer to jointly build the carrier basis of the "moisture absorption - water locking - film forming" three-level moisturizing system. This combination ensures mildness and no irritation while meeting the emulsification requirements of high oil-phase content such as 26# white oil. In short, their synergistic effect ensures that the lotion provides moisturization without burdening the skin and is suitable for various skin types.

[0016] Preferably, the skin conditioner is behenyl trimethyl ammonium methyl sulfate.

[0017] Preferably, the pH regulator is an aqueous sodium hydroxide solution with a mass concentration of 20%; the fragrance is rose essential oil.

[0018] Preferably, the preservative consists of phenoxyethanol and ethylhexylglycerin in a mass ratio of 1:2.

[0019] In a second aspect, the present application provides a preparation method of a highly efficient moisturizing lotion composition, adopting the following technical solution: As a general technical concept, the present application also provides a preparation method of the above highly efficient moisturizing lotion composition, including the following steps: S101. According to the mass parts: Add the components in phase A to the emulsifying pan in sequence, stir and disperse at a stirring speed of 40 r / min, and heat to 85 °C to obtain the phase A material; S102. According to the mass parts: Add the components in phase B to the oil pan in sequence, heat to 85 °C and dissolve completely to obtain the phase B material; S103. By mass parts: Add the phase B material to the emulsifying pot of the phase A material, and homogenize while stirring at 50 r / min for 5 minutes to obtain the mixture A; S104. By mass parts: Add the acrylate / methacrylic acid ammonium copolymer to the mixture A, homogenize while stirring at 50 r / min for 5 minutes, stir and keep warm at 40 r / min for 20 minutes, evacuate to remove bubbles, and cool to 45 °C while stirring at 40 r / min to obtain the mixture B; S105. By mass parts: Sequentially add the pH regulator, preservative, and essence to the mixture B, and stir and disperse evenly at 40 r / min to prepare the high-efficiency moisturizing body lotion composition.

[0020] In summary, the beneficial technical effects of the present application are as follows: 1. The "moisture absorption - water locking - film forming" three-level moisturizing system breaks through the traditional moisturizing bottleneck Construct a "moisture absorption - water locking - film forming" dynamic moisturizing network with glycerol (moisture absorption), cross-linked sodium hyaluronate (water locking), and hydroxyethyl urea (film forming): Glycerol captures environmental moisture through strong hygroscopicity of hydroxyl groups, cross-linked sodium hyaluronate forms a 3D network structure to lock water, and hydroxyethyl urea forms a breathable film on the skin surface to achieve continuous moisturizing for 12 hours. The prepared cross-linked sodium hyaluronate enhances moisturizing property and biocompatibility, providing a mild, non-irritating, highly stable, and excellent moisturizing effect for the body lotion composition.

[0021] 2. The multi-dimensional emulsification system innovates product stability and promotes rapid absorption Use a thickening agent (xanthan gum + carbomer U20) and cetyl / stearyl alcohol for synergistic emulsification to achieve high stability at low viscosity and promote rapid absorption. Ethylhexyl isononanoate improves spreadability, reduces greasiness, and promotes the penetration of active ingredients.

[0022] 3. Bionic lipid barrier repair technology Shea butter and vitamin E form a sebum-like film structure, which acts synergistically to supplement lipids and antioxidant, enhancing the skin barrier function. Shea butter is a natural lipid source, rich in fatty acids, strengthening the skin barrier and repairing dry and damaged skin. Specific embodiments

[0023] The following will describe the implementation schemes of the present application in detail in combination with examples and preparation examples. However, those skilled in the art will understand that the following examples and preparation examples are only used to illustrate the present application and should not be regarded as limiting the scope of the present application. For those not specifying specific conditions in the examples and preparation examples, they are carried out according to conventional conditions or conditions recommended by the manufacturer. For reagents or instruments not indicating the manufacturer, they are all conventional products that can be obtained through commercial purchase.

[0024] In the following examples and preparation examples, 1 part represents 100 g.

[0025] Preparation Example 1 Preparation of Cross-linked Sodium Hyaluronate The preparation method of cross-linked sodium hyaluronate comprises the following steps: S41. Add 15 parts of sodium hyaluronate with a molecular weight of 80,000 Daltons and 5 parts of NaCl to 500 parts of a 0.04% NaOH solution, respectively, by mass, and stir at room temperature until completely dissolved to obtain a mixed solution A; S42, according to the mass fraction: take 3 parts of polyglycerol polyglycidyl ether, dilute with 300 parts of distilled water and stir evenly to obtain a polyglycerol polyglycidyl ether solution; S43, heating the mixed solution A to 43° C., maintaining a constant temperature, and dropping the polyglycerol polyglycidyl ether solution into the mixed solution A, and completing the dropping within 80 minutes. After the dropping is completed, continue the constant temperature reaction for 9.5 hours; S44, according to the mass fraction: adding 0.02 mol / L citric acid solution to adjust the pH to 7.3, stirring for 3.4 hours, and then adding 1200 parts of anhydrous ethanol, precipitating for 6.7 hours to obtain a block solid; S45. Freeze the solid block at -70°C and vacuum pressure of 80Pa for 24 hours, and then dialyze it for 24 hours at a rate of 1g solid block: 300mL saline. Freeze-dry the dialyzed gel again to obtain cross-linked sodium hyaluronate.

[0026] Example 1 A highly effective moisturizing body lotion composition, wherein the raw material components of the body lotion composition include phase A, phase B, phase C, phase D and phase E; the phase A, by weight, includes the following raw materials: 72 parts of deionized water, 0.04 parts of EDTA-2Na, 0.09 parts of allantoin, 2.0 parts of a moisturizer, and 0.25 parts of a thickener; the phase B, by weight, includes the following raw materials: 1.4 parts of 16 / 18 alcohol, 9 parts of 26# white oil, 2.8 parts of ethylhexyl isononanoate, 0.45 parts of vitamin E, 0.9 parts of shea butter, 1.2 parts of a composite surfactant, 0.9 parts of stearic acid, 0.7 parts of glyceryl stearate, and 0.45 parts of behenyltrimethylammonium methyl sulfate; the phase C, by weight, includes The preparation material comprises the following raw materials: 0.45 parts of acrylic acid (ester) / ammonium methacrylate copolymer; the D phase comprises the following raw materials by mass: 0.08 parts of sodium hydroxide aqueous solution with a mass concentration of 20%; the E phase comprises the following raw materials by mass: 0.5 parts of preservatives and 0.45 parts of rose essential oil, the moisturizer comprises glycerin, cross-linked sodium hyaluronate and hydroxyethyl urea in a mass ratio of 20:1:1, the thickener comprises xanthan gum and carbomer U20 in a mass ratio of 1:2, the composite surfactant comprises sodium lauroyl lactylate and polysorbate-60 in a mass ratio of 5:8, and the preservative comprises phenoxyethanol and oxyphenesin in a mass ratio of 1:2; The preparation method of the above-mentioned high-efficiency moisturizing lotion composition comprises the following steps: S101, according to the mass fractions: add the components in phase A into an emulsifying pot in order, stir and disperse at a stirring speed of 40 r / min, and heat to 85° C. to obtain phase A material; S102, according to the mass fractions: add the components in phase B into the oil pan in order, heat to 85°C and completely dissolve, to obtain phase B material; S103, according to the mass fractions: add the phase B material into the phase A emulsifier, and homogenize at 50 r / min while stirring for 5 minutes to obtain a mixture A; S104, according to the mass fractions: add acrylic acid (ester) / ammonium methacrylate copolymer to mixed material A, stir and homogenize at 50 r / min for 5 minutes, stir and keep warm at 40 r / min for 20 minutes, evacuate and defoam, and cool to 45° C. at 40 r / min while stirring to obtain mixed material B; S105. Add 20% sodium hydroxide aqueous solution, preservative and rose essential oil to mixed material B in order according to their mass fractions, and stir at 40 r / min to disperse them evenly to obtain a highly effective moisturizing lotion composition.

[0027] Example 2 A highly effective moisturizing body lotion composition, wherein the raw material components of the body lotion composition include phase A, phase B, phase C, phase D and phase E; the phase A, by weight, includes the following raw materials: 75 parts of deionized water, 0.06 parts of EDTA-2Na, 0.11 parts of allantoin, 2.3 parts of a moisturizer, and 0.35 parts of a thickener; the phase B, by weight, includes the following raw materials: 1.6 parts of 16 / 18 alcohol, 11 parts of 26# white oil, 3.2 parts of ethylhexyl isononanoate, 0.55 parts of vitamin E, 1.1 parts of shea butter, 1.4 parts of a composite surfactant, 1.1 parts of stearic acid, 0.9 parts of glyceryl stearate, and 0.55 parts of behenyltrimethylammonium methyl sulfate; the phase C, by weight, The invention comprises the following raw materials: 0.55 parts of acrylic acid (ester) / ammonium methacrylate copolymer; the phase D comprises the following raw materials by weight: 0.12 parts of sodium hydroxide aqueous solution with a mass concentration of 20%; the phase E comprises the following raw materials by weight: 0.6 parts of preservatives and 0.55 parts of rose essential oil, the moisturizer comprises glycerin, cross-linked sodium hyaluronate and hydroxyethyl urea in a mass ratio of 20:1:1, the thickener comprises xanthan gum and carbomer U20 in a mass ratio of 1:2, the composite surfactant comprises sodium lauroyl lactylate and polysorbate-60 in a mass ratio of 5:8, and the preservative comprises phenoxyethanol and oxyphenesin in a mass ratio of 1:2; The preparation method of the above-mentioned high-efficiency moisturizing lotion composition comprises the following steps: S101, according to the mass fractions: add the components in phase A into an emulsifying pot in order, stir and disperse at a stirring speed of 40 r / min, and heat to 85° C. to obtain phase A material; S102, according to the mass fractions: add the components in phase B into the oil pan in order, heat to 85°C and completely dissolve, to obtain phase B material; S103, according to the mass fractions: add the phase B material into the phase A emulsifier, and homogenize at 50 r / min while stirring for 5 minutes to obtain a mixture A; S104, according to the mass fractions: add acrylic acid (ester) / ammonium methacrylate copolymer to mixed material A, stir and homogenize at 50 r / min for 5 minutes, stir and keep warm at 40 r / min for 20 minutes, evacuate and defoam, and cool to 45° C. at 40 r / min while stirring to obtain mixed material B; S105. Add 20% sodium hydroxide aqueous solution, preservative and rose essential oil to mixed material B in order according to their mass fractions, and stir at 40 r / min to disperse them evenly to obtain a highly effective moisturizing lotion composition.

[0028] Example 3 A highly effective moisturizing body lotion composition, wherein the raw material components of the body lotion composition include phase A, phase B, phase C, phase D and phase E; the phase A, by weight, includes the following raw materials: 74 parts of deionized water, 0.05 parts of EDTA-2Na, 0.1 parts of allantoin, 2.2 parts of a moisturizer, and 0.3 parts of a thickener; the phase B, by weight, includes the following raw materials: 1.5 parts of 16 / 18 alcohol, 10 parts of 26# white oil, 3 parts of ethylhexyl isononanoate, 0.5 parts of vitamin E, 1 part of shea butter, 1.3 parts of a composite surfactant, 1 part of stearic acid, 0.8 parts of glyceryl stearate, and 0.5 parts of behenyltrimethylammonium methyl sulfate; the phase C, by weight, includes the following raw materials: acrylic acid (ester) / 0.5 parts of ammonium methacrylate copolymer; the D phase, by mass, includes the following raw materials: 0.1 parts of sodium hydroxide aqueous solution with a mass concentration of 20%; the E phase, by mass, includes the following raw materials: 0.55 parts of preservatives, 0.5 parts of rose essential oil, the moisturizer is composed of glycerol, cross-linked sodium hyaluronate and hydroxyethyl urea in a mass ratio of 20:1:1, the thickener is composed of xanthan gum and carbomer U20 in a mass ratio of 1:2, the composite surfactant is composed of sodium lauroyl lactylate and polysorbate-60 in a mass ratio of 5:8, and the preservative is composed of phenoxyethanol and oxyphenesin in a mass ratio of 1:2; the preparation method of the above-mentioned high-efficiency moisturizing lotion composition comprises the following steps: S101, according to the mass fractions: add the components in phase A into an emulsifying pot in order, stir and disperse at a stirring speed of 40 r / min, and heat to 85° C. to obtain phase A material; S102, according to the mass fractions: add the components in phase B into the oil pan in order, heat to 85°C and completely dissolve, to obtain phase B material; S103, according to the mass fractions: add the phase B material into the phase A emulsifier, and homogenize at 50 r / min while stirring for 5 minutes to obtain a mixture A; S104, according to the mass fractions: add acrylic acid (ester) / ammonium methacrylate copolymer to mixed material A, stir and homogenize at 50 r / min for 5 minutes, stir and keep warm at 40 r / min for 20 minutes, evacuate and defoam, and cool to 45° C. at 40 r / min while stirring to obtain mixed material B; S105. Add 20% sodium hydroxide aqueous solution, preservative and rose essential oil to mixed material B in order according to their mass fractions, and stir at 40 r / min to disperse them evenly to obtain a highly effective moisturizing lotion composition.

[0029] Comparative Example 1 The same as Example 3, except that an equal amount of unmodified sodium hyaluronate is used instead of cross-linked sodium hyaluronate.

[0030] Comparative Example 2 Same as Example 3, except that the moisturizer is composed of glycerol and cross-linked sodium hyaluronate in a mass ratio of 20:2.

[0031] Comparative Example 3 Same as Example 3, except that the moisturizer is composed of glycerol and hydroxyethyl urea in a mass ratio of 20:2.

[0032] Comparative Example 4 Same as Example 3, except that the composite surfactant is sodium lauroyl lactylate.

[0033] Comparative Example 5 Same as Example 3, except that the composite surfactant is polysorbate - 60.

[0034] Comparative Example 6 Same as Example 3, except that vitamin E is 0 part and shea butter is 0 part.

[0035] Performance Test Samples of the highly moisturizing body lotion compositions prepared in Examples 1 - 3 and Comparative Examples 1 - 6 were taken respectively and subjected to the following tests.

[0036] 1. Stability Test: Samples of the highly moisturizing body lotion compositions prepared in Examples 1 - 3 and Comparative Examples 1 - 6 were taken respectively, and stability experiments were carried out on the samples according to the national light industry industry standard QB / T 1645 - 2004. Heat resistance performance test: Keep at (40 ± 1)°C for 3 months, and observe the product properties after returning to room temperature. Cold resistance performance test: Keep in a - 10°C refrigerator for 3 months, and observe the product properties after returning to room temperature. The results are shown in Table 1.

[0037] 2. Tewl Test The trans - epidermal water loss rate (Tewl) refers to the rate of trans - epidermal water loss per unit time and per unit cross - sectional area. The higher the Tewl, the more water is lost per unit time, and the weaker the skin moisturizing ability.

[0038] Test method: Select 90 volunteers, evenly divide them into 9 groups with 10 people in each group, and respectively try the highly moisturizing body lotion groups prepared in the above Examples 1 - 3 and Comparative Examples 1 - 6. Test under the environment of temperature 20 - 22°C and humidity 50%RH. Volunteers in each group use the same test sample, and the test site is an area of 6 cm × 6 cm on the inner side of the arm, fixed with a mold, and no other cosmetics can be used during the test. Before using the sample, use a trans - epidermal water loss measuring instrument to test and take the average value. The sample usage amount is 5.5 mg / cm 2, after 2 hours, 4 hours, 8 hours, and 12 hours of use, the transdermal water loss meter was used for testing again, and the mean value was taken. The results are shown in Table 2.

[0039] 3. Absorption rate: The Franz diffusion cell method (ex vivo porcine skin) was used to measure the transdermal rate of the active ingredient through ex vivo porcine skin at 5 minutes. The results are shown in Table 3.

[0040] 4. Irritation test (chorioallantoic membrane blood vessel test of chicken embryo) Samples of the highly effective moisturizing body lotion compositions prepared in Examples 1 - 3 and Comparative Examples 1 - 6 were taken respectively, and tested according to the test method of "Chorioallantoic Membrane Blood Vessel Test for Cosmetic Eye Irritation" in SN / T2329 - 2009. The results are shown in Table 3.

[0041] Table 1 Stability test Table 2 Tewl test Table 3 Absorption rate and irritation test Project Absorption rate / % Irritation Example 1 94.5 1.6 Example 2 94.8 1.5 Example 3 95.6 1.3 Comparative Example 1 92.4 1.8 Comparative Example 2 93.1 1.5 Comparative Example 3 90.2 1.9 Comparative Example 4 91.9 2.5 Comparative Example 5 89.8 2.1 Comparative Example 6 92.4 3.3 Analyzing the data in Tables 1, 2, and 3, it can be seen that: 1) The highly effective moisturizing body lotion compositions prepared in Examples 1 - 3 are mild, non - irritating, highly stable, have excellent moisturizing effects, and fast absorption. The Tewl values of Examples 1 - 3 are still lower than the initial values at 12 hours.

[0042] 2) Through the comparative analysis of the performance of the highly effective moisturizing body lotion compositions prepared by combining Example 3 and Comparative Example 1, it shows that the cross - linked sodium hyaluronate prepared in this application, prepared by cross - linking sodium hyaluronate with polyglycerol polyglycidyl ether, enhances the moisturizing property and biocompatibility. The cross - linked sodium hyaluronate has high stability and viscoelasticity, and can provide mildness, non - irritation, high stability, and excellent moisturizing effects in the body lotion composition.

[0043] 3) Combining the performance comparative analysis of the high-efficiency moisturizing body lotion compositions prepared in Example 3 and Comparative Examples 2 - 3 shows that the humectant consists of glycerol, sodium hyaluronate cross polymer and hydroxyethyl urea in a mass ratio of 20:1:1. The synergistic effect among these three components is mainly reflected in the following aspects: 1. Moisture absorption - water locking - film formation: Glycerol, as a humectant, can absorb moisture from the environment; sodium hyaluronate cross polymer, as a water locking agent, can form a protective film on the skin surface to prevent water loss; hydroxyethyl urea, as a film forming agent, helps the skin retain moisture and promotes the absorption of other active ingredients. 2. Enhancing the moisturizing effect: The combined use of these three components can significantly extend the moisturizing time and improve the moisturizing effect of the skin. 3. Promoting skin health: The combined use of these three components can help the skin retain moisture, prevent dryness and dehydration, thus promoting skin health. 4. Improving the stability of the product: The combined use of these three components can improve the stability of the product and extend the shelf life of the product.

[0044] 4) Combining the performance comparative analysis of the high-efficiency moisturizing body lotion compositions prepared in Example 3 and Comparative Examples 4 - 5 shows that the compound surfactant consists of sodium lauroyl lactylate and polysorbate - 60 in a mass ratio of 5:8. By utilizing their synergistic effect, the comprehensive performance of the body lotion composition can be enhanced.

[0045] 5) Combining the performance comparative analysis of the high-efficiency moisturizing body lotion compositions prepared in Example 3 and Comparative Example 6 shows that adding shea butter and vitamin E, by utilizing their synergistic effect, can supplement lipids and have antioxidant properties, enhancing the skin barrier function.

[0046] The above embodiments are only used to explain and illustrate the technical solutions of the present application rather than to limit them. Although the above embodiments have specifically described the present application, those skilled in the art should understand that the specific implementation manners of the present application can still be modified or equivalently replaced. Any modification and equivalent replacement without departing from the spirit and scope of the present application shall be covered by the protection scope of the present application.

Claims

1. An efficient moisturizing body lotion composition, characterized in that, The raw material components of the body lotion composition include phase A, phase B, phase C, phase D and phase E; the phase A, calculated by mass, includes the following raw materials: 72-75 parts of deionized water, 0.04-0.06 parts of EDTA-2Na, 0.09-0.11 parts of allantoin, 2.0-2.3 parts of moisturizer, and 0.25-0.35 parts of thickener; the phase B, calculated by mass, includes the following raw materials: 1.4-1.6 parts of 16 / 18 alcohol, 9-11 parts of 26# white oil, 2.8-3.2 parts of ethylhexyl isononanoate, 0.45-0.55 parts of vitamin E, and 0.25-0.35 parts of shea butter. 0.9-1.1 parts of fruit oil, 1.2-1.4 parts of complex surfactant, 0.9-1.1 parts of stearic acid, 0.7-0.9 parts of glyceryl stearate, 0.45-0.55 parts of skin conditioner; the C phase, calculated by mass, includes the following raw materials: 0.45-0.55 parts of acrylic acid (ester) / ammonium methacrylate copolymer; the D phase, calculated by mass, includes the following raw materials: 0.08-0.12 parts of pH adjuster; the E phase, calculated by mass, includes the following raw materials: 0.5-0.6 parts of preservatives, 0.45-0.55 parts of flavor.

2. The high-efficiency moisturizing skin lotion composition according to claim 1, characterized in that The moisturizing agent consists of glycerin, cross-linked sodium hyaluronate and hydroxyethyl urea in a mass ratio of 20:1:

1.

3. The high-efficiency moisturizing skin lotion composition according to claim 2, characterized in that The cross-linked sodium hyaluronate is sodium hyaluronate having a molecular weight of 50,000-100,000 Daltons, which is obtained by cross-linking with a cross-linking agent, polyglycerol polyglycidyl ether.

4. The high-efficiency moisturizing skin lotion composition according to claim 3, wherein The preparation method of the cross-linked sodium hyaluronate comprises the following steps: S41, according to the mass fractions: 15 parts of sodium hyaluronate with a molecular weight of 50,000-100,000 Daltons and 5 parts of NaCl are added to 500 parts of a 0.04% NaOH solution, respectively, and stirred at room temperature until completely dissolved to obtain a mixed solution A; S42, according to the mass fraction: take 3 parts of polyglycerol polyglycidyl ether, dilute with 300 parts of distilled water and stir evenly to obtain a polyglycerol polyglycidyl ether solution; S43, heating the mixed solution A to 43° C., maintaining a constant temperature, and dropping the polyglycerol polyglycidyl ether solution into the mixed solution A, and completing the dropping within 80 minutes. After the dropping is completed, continue the constant temperature reaction for 9-10 hours; S44, according to the mass fraction: add 0.02 mol / L citric acid solution to adjust the pH to 7.2-7.4, stir for 3-4 hours, then add 1200 parts of anhydrous ethanol, precipitate for 6-7 hours to obtain a block solid; S45. Freeze the solid block at -70°C and vacuum pressure of 80Pa for 24 hours, and then dialyze it for 24 hours at a rate of 1g solid block: 300mL saline. Freeze-dry the dialyzed gel again to obtain cross-linked sodium hyaluronate.

5. The high-efficiency moisturizing skin lotion composition according to claim 1, wherein The thickener is composed of xanthan gum and carbomer U20 in a mass ratio of 1:

2.

6. The high-efficiency moisturizing skin lotion composition according to claim 1, characterized in that, The composite surfactant is composed of sodium lauroyl lactylate and polysorbate-60 in a mass ratio of 5:

8.

7. The high-efficiency moisturizing skin lotion composition according to claim 1, characterized in that The skin conditioning agent is behentrimonium methylsulfate.

8. The high-efficiency moisturizing skin lotion composition according to claim 1, wherein, The pH regulator is an aqueous sodium hydroxide solution with a mass concentration of 20%; the essence is rose essential oil.

9. The high-efficiency moisturizing skin lotion composition according to claim 1, wherein The preservative is composed of phenoxyethanol and phenoxyglycerin in a mass ratio of 1:

2.

10. A method for preparing the high-efficiency moisturizing skin lotion composition according to any one of claims 1-9, characterized in that, It includes the following steps: S101. According to the parts by mass: Add the components in phase A to the emulsifying pot in sequence, stir and disperse at a stirring speed of 40 r / min, and heat to 85 °C to obtain the phase A material. S102. According to the parts by mass: Add the components in phase B to the oil pan in sequence, heat to 85 °C and dissolve completely to obtain the phase B material. S103. According to the parts by mass: Add the phase B material to the phase A material in the emulsifying pot, homogenize while stirring at 50 r / min for 5 minutes to obtain the mixture A. S104. According to the parts by mass: Add the acrylate / methacrylic acid ammonium copolymer to the mixture A, homogenize while stirring at 50 r / min for 5 minutes, stir and keep warm at 40 r / min for 20 minutes, evacuate to remove bubbles, and cool to 45 °C while stirring at 40 r / min to obtain the mixture B. S105. According to the parts by mass: Add the pH regulator, preservative and essence to the mixture B in sequence, stir and disperse evenly at 40 r / min to prepare the high-efficiency moisturizing body lotion composition.

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